Guide to the Human Genome
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Search of human proteins with 222831590

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222831590 glutaminyl-tRNA synthase
(glutamine-hydrolyzing)-like 1 [Homo sapiens]
         (528 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222831590 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-li...  1050   0.0  
gi|195972892 fatty acid amide hydrolase 2 [Homo sapiens]               89   1e-17
gi|166795287 fatty acid amide hydrolase [Homo sapiens]                 80   5e-15
gi|87298840 alkylated DNA repair protein alkB homolog [Homo sapi...    34   0.29 
gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]             32   1.4  
gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]             32   1.4  
gi|239752133 PREDICTED: hypothetical protein [Homo sapiens]            32   1.9  
gi|239746658 PREDICTED: hypothetical protein [Homo sapiens]            32   1.9  
gi|4505379 nuclear factor erythroid 2-like 1 [Homo sapiens]            30   4.2  
gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo ...    30   7.1  
gi|226442729 kelch-like 15 [Homo sapiens]                              29   9.3  

>gi|222831590 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like
           1 [Homo sapiens]
          Length = 528

 Score = 1050 bits (2716), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYK 60
           MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYK
Sbjct: 1   MLGRSLREVSAALKQGQITPTELCQKCLSLIKKTKFLNAYITVSEEVALKQAEESEKRYK 60

Query: 61  NGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTN 120
           NGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTN
Sbjct: 61  NGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKTN 120

Query: 121 LDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVS 180
           LDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVS
Sbjct: 121 LDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVS 180

Query: 181 AFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDA 240
           AFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDA
Sbjct: 181 AFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDVPGILTRCVDDA 240

Query: 241 AIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSK 300
           AIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSK
Sbjct: 241 AIVLGALAGPDPRDSTTVHEPINKPFMLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSK 300

Query: 301 AADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVSTEAM 360
           AADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVSTEAM
Sbjct: 301 AADLFESEGAKVIEVSLPHTSYSIVCYHVLCTSEVASNMARFDGLQYGHRCDIDVSTEAM 360

Query: 361 YAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLT 420
           YAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLT
Sbjct: 361 YAATRREGFNDVVRGRILSGNFFLLKENYENYFVKAQKVRRLIANDFVNAFNSGVDVLLT 420

Query: 421 PTTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGR 480
           PTTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGR
Sbjct: 421 PTTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGR 480

Query: 481 AFCDQQLLTVAKWFEKQVQFPVIQLQELMDDCSAVLENEKLASVSLKQ 528
           AFCDQQLLTVAKWFEKQVQFPVIQLQELMDDCSAVLENEKLASVSLKQ
Sbjct: 481 AFCDQQLLTVAKWFEKQVQFPVIQLQELMDDCSAVLENEKLASVSLKQ 528


>gi|195972892 fatty acid amide hydrolase 2 [Homo sapiens]
          Length = 532

 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 71/255 (27%), Positives = 116/255 (45%), Gaps = 32/255 (12%)

Query: 8   EVSAALKQGQITPTELCQKCLSLIKKTK-FLNAYITVSEEVALKQAEESEKRYKNGQ--- 63
           +++  ++Q ++   ++ Q  ++ IK     +N  +    E A+K+A   +++    Q   
Sbjct: 55  QLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDE 114

Query: 64  ----SLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGALLMGKT 119
               +     G+P+ VK+ F   G+  +      +  I   +ATVV  L   GA+ +G T
Sbjct: 115 ATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGIT 174

Query: 120 NLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAV 179
           N  E  M   S++ ++G   NP  Y  Q+                  I GGSSGG    +
Sbjct: 175 NCSELCMWYESSNKIYGRSNNP--YDLQH------------------IVGGSSGGEGCTL 214

Query: 180 SAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPL-VNSMDV---PGILTR 235
           +A      +GSD GGS R PA   G+ G KPS G+V   G  PL V + ++    G + R
Sbjct: 215 AAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCR 274

Query: 236 CVDDAAIVLGALAGP 250
             +D A +L  +AGP
Sbjct: 275 YAEDLAPMLKVMAGP 289



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 18/49 (36%), Positives = 28/49 (57%)

Query: 448 FTQAVNMAGLPAVSIPVALSNQGLPIGLQFIGRAFCDQQLLTVAKWFEK 496
           +T   +  GLP    P+ L+ +GLP+G+Q +   F D   L VA++ EK
Sbjct: 473 YTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEK 521


>gi|166795287 fatty acid amide hydrolase [Homo sapiens]
          Length = 579

 Score = 80.1 bits (196), Expect = 5e-15
 Identities = 57/202 (28%), Positives = 91/202 (45%), Gaps = 24/202 (11%)

Query: 54  ESEKRYKNGQSLGDLDGIPIAVKDNFSTSGIETTCASNMLKGYIPPYNATVVQKLLDQGA 113
           + E +       G L G+P+++K+ F+  G ++T   ++ +G     ++ VV  L  QGA
Sbjct: 120 DCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGA 179

Query: 114 LLMGKTNLDEFAMGSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSG 173
           +    TN+ +       ++ +FG   NPW  SK                      GGSSG
Sbjct: 180 VPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKS--------------------PGGSSG 219

Query: 174 GSAAAVSAFTCYAALGSDTGGSTRNPAAHCGLVGFKPSYGLVSRHGLIPLVNSMDV---- 229
           G  A + +      LG+D GGS R P++ CG+ G KP+   +S+ GL   V   +     
Sbjct: 220 GEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLS 279

Query: 230 PGILTRCVDDAAIVLGALAGPD 251
            G + R V+  A+ L AL   D
Sbjct: 280 VGPMARDVESLALCLRALLCED 301


>gi|87298840 alkylated DNA repair protein alkB homolog [Homo
           sapiens]
          Length = 389

 Score = 34.3 bits (77), Expect = 0.29
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 4/82 (4%)

Query: 142 WSYSKQ---YREKRKQNPHSENEDSDWLITGGSSGGSAAAVSAFTCYAALGSDTGGSTRN 198
           W  SK+   Y+E  K+ P S  E   W+  G      +   SA   Y    SD G  +  
Sbjct: 144 WEQSKEFLRYKEATKRRPRSLLEKLRWVTVGYHYNWDSKKYSA-DHYTPFPSDLGFLSEQ 202

Query: 199 PAAHCGLVGFKPSYGLVSRHGL 220
            AA CG   F+   G+++ + L
Sbjct: 203 VAAACGFEDFRAEAGILNYYRL 224


>gi|38569428 ankyrin repeat domain protein 5 [Homo sapiens]
          Length = 776

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 20/72 (27%)

Query: 53  EESEKRYKNGQSL---GDL--------DGIPIAVKDNFSTSGIETTCASNMLKGYIPPYN 101
           ++SEK + N   +   GDL         GIP+ +KDN+  + + T CAS          N
Sbjct: 487 DDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASG---------N 537

Query: 102 ATVVQKLLDQGA 113
             VV+ LL++GA
Sbjct: 538 IDVVKFLLEKGA 549


>gi|38569426 ankyrin repeat domain protein 5 [Homo sapiens]
          Length = 776

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 24/72 (33%), Positives = 36/72 (50%), Gaps = 20/72 (27%)

Query: 53  EESEKRYKNGQSL---GDL--------DGIPIAVKDNFSTSGIETTCASNMLKGYIPPYN 101
           ++SEK + N   +   GDL         GIP+ +KDN+  + + T CAS          N
Sbjct: 487 DDSEKVFSNINIITKAGDLASLKKAFESGIPVDMKDNYYKTPLMTACASG---------N 537

Query: 102 ATVVQKLLDQGA 113
             VV+ LL++GA
Sbjct: 538 IDVVKFLLEKGA 549


>gi|239752133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 224

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 9/77 (11%)

Query: 127 GSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVSAFTCYA 186
           G+G   G   P + P  Y+      R+  P S      W  TG S+   AAAV A  C A
Sbjct: 56  GAGPGAGSAPPGETPAPYT------RRSGPRSRTWRRTWCWTGDSAAVGAAAVLA--CSA 107

Query: 187 ALG-SDTGGSTRNPAAH 202
            L  +D  G+   P AH
Sbjct: 108 RLSPADGFGAEEGPLAH 124


>gi|239746658 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 411

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 9/77 (11%)

Query: 127 GSGSTDGVFGPVKNPWSYSKQYREKRKQNPHSENEDSDWLITGGSSGGSAAAVSAFTCYA 186
           G+G   G   P + P  Y+      R+  P S      W  TG S+   AAAV A  C A
Sbjct: 243 GAGPGAGSAPPGETPAPYT------RRSGPRSRTWRRTWCWTGDSAAVGAAAVLA--CSA 294

Query: 187 ALG-SDTGGSTRNPAAH 202
            L  +D  G+   P AH
Sbjct: 295 RLSPADGFGAEEGPLAH 311


>gi|4505379 nuclear factor erythroid 2-like 1 [Homo sapiens]
          Length = 772

 Score = 30.4 bits (67), Expect = 4.2
 Identities = 40/167 (23%), Positives = 70/167 (41%), Gaps = 27/167 (16%)

Query: 71  IPIAVKDNFSTSGIETTCASNMLKGYIPPY-----NATVVQKLLDQGALLMGKTNLDEFA 125
           +P+A  +  STS   T  ++N+   + PP      N T   +L D    L+ +  LDE +
Sbjct: 394 LPLAPSN--STSLNSTFGSTNLTGLFFPPQLNGTANDTAGPELPDPLGGLLDEAMLDEIS 451

Query: 126 MGSGSTDGVFGPVKNPWSYSKQYREK------------RKQNPHSENEDSDWLITGGSSG 173
           +   + +  F PV+     + Q  E+               +  S +E S    +  SS 
Sbjct: 452 LMDLAIEEGFNPVQ-----ASQLEEEFDSDSGLSLDSSHSPSSLSSSEGSSSSSSSSSSS 506

Query: 174 GSAAAVSAFTCYA---ALGSDTGGSTRNPAAHCGLVGFKPSYGLVSR 217
            S+A+ SA + ++   A+G  +   T +     G VG++P Y    R
Sbjct: 507 SSSASSSASSSFSEEGAVGYSSDSETLDLEEAEGAVGYQPEYSKFCR 553


>gi|115529486 ATPase, Cu++ transporting, alpha polypeptide [Homo
           sapiens]
          Length = 1500

 Score = 29.6 bits (65), Expect = 7.1
 Identities = 20/80 (25%), Positives = 39/80 (48%), Gaps = 8/80 (10%)

Query: 267 MLPSLADVSKLCIGIPKEYLVPELSSEVQSLWSKAADLFESEGAKVIEVSLPHTSYSIVC 326
           ++PS+ + +++      + LVPELS +  +L  K+    +   A+  EV L      + C
Sbjct: 129 IIPSIVNANQI------KELVPELSLDTGTLEKKSGACEDHSMAQAGEVVLKMKVEGMTC 182

Query: 327 YHVLCTSEVASNMARFDGLQ 346
           +   CTS +   + +  G+Q
Sbjct: 183 HS--CTSTIEGKIGKLQGVQ 200


>gi|226442729 kelch-like 15 [Homo sapiens]
          Length = 604

 Score = 29.3 bits (64), Expect = 9.3
 Identities = 26/107 (24%), Positives = 47/107 (43%), Gaps = 11/107 (10%)

Query: 418 LLTPTTLSEAVPYLEFIKEDNRTRSAQDDIFTQAVNMAGLPAVSIPVALSNQGLPIGLQF 477
           L+TPT++ E V   EF +   + R   D       N+   P + +  +      P    F
Sbjct: 226 LMTPTSVFEKVKTSEFYRYSRQLRYEVDQALNYFQNVHQQPLLDMKSSRIRSAKPQTTVF 285

Query: 478 ---IGRAFCDQQLLTVAK---WFEKQVQFPVIQLQELMDDCSAVLEN 518
              IG +  + ++L + K   W+E  ++ P + L+    DC A++ N
Sbjct: 286 RGMIGHSMVNSKILLLKKPRVWWE--LEGPQVPLR---PDCLAIVNN 327


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,198,829
Number of Sequences: 37866
Number of extensions: 843667
Number of successful extensions: 2217
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2210
Number of HSP's gapped (non-prelim): 12
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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