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Search of human proteins with 22165431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22165431 annexin A11 [Homo sapiens]
(505 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557317 annexin A11 [Homo sapiens] 1046 0.0
gi|22165433 annexin A11 [Homo sapiens] 1046 0.0
gi|22165431 annexin A11 [Homo sapiens] 1046 0.0
gi|4502111 annexin VII isoform 1 [Homo sapiens] 432 e-121
gi|4809279 annexin VII isoform 2 [Homo sapiens] 421 e-118
gi|4502105 annexin IV [Homo sapiens] 372 e-103
gi|71773415 annexin VI isoform 2 [Homo sapiens] 359 4e-99
gi|71773329 annexin VI isoform 1 [Homo sapiens] 359 4e-99
gi|4502107 annexin 5 [Homo sapiens] 337 1e-92
gi|4826643 annexin A3 [Homo sapiens] 332 6e-91
gi|91807122 annexin A8L2 [Homo sapiens] 322 4e-88
gi|91823262 annexin A8 [Homo sapiens] 320 2e-87
gi|149588958 annexin A8-like 1 [Homo sapiens] 318 7e-87
gi|4757756 annexin A2 isoform 2 [Homo sapiens] 295 9e-80
gi|50845386 annexin A2 isoform 2 [Homo sapiens] 295 9e-80
gi|50845388 annexin A2 isoform 1 [Homo sapiens] 295 9e-80
gi|209862831 annexin A2 isoform 2 [Homo sapiens] 295 9e-80
gi|4502101 annexin I [Homo sapiens] 294 1e-79
gi|51896029 annexin A13 isoform b [Homo sapiens] 291 9e-79
gi|51895795 annexin A13 isoform a [Homo sapiens] 290 2e-78
gi|48762937 annexin A10 [Homo sapiens] 262 5e-70
gi|145864465 annexin A9 [Homo sapiens] 213 3e-55
gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo ... 115 9e-26
gi|160707881 formin 2 [Homo sapiens] 96 1e-19
gi|11386183 WAS protein family, member 2 [Homo sapiens] 87 3e-17
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 82 9e-16
gi|150417989 cyclin K isoform 1 [Homo sapiens] 80 6e-15
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 78 2e-14
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 74 3e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 73 5e-13
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 1046 bits (2706), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
Sbjct: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
Sbjct: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
Query: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
Sbjct: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
Query: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
Sbjct: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
Query: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
Sbjct: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
Query: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
Sbjct: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
Sbjct: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
Sbjct: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LYHDISGDTSGDYRKILLKICGGND
Sbjct: 481 LYHDISGDTSGDYRKILLKICGGND 505
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 1046 bits (2706), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
Sbjct: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
Sbjct: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
Query: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
Sbjct: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
Query: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
Sbjct: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
Query: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
Sbjct: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
Query: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
Sbjct: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
Sbjct: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
Sbjct: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LYHDISGDTSGDYRKILLKICGGND
Sbjct: 481 LYHDISGDTSGDYRKILLKICGGND 505
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 1046 bits (2706), Expect = 0.0
Identities = 505/505 (100%), Positives = 505/505 (100%)
Query: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN
Sbjct: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY
Sbjct: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSY 120
Query: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT
Sbjct: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
Query: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL
Sbjct: 181 PAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILL 240
Query: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA
Sbjct: 241 SFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILA 300
Query: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD
Sbjct: 301 SRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRD 360
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE
Sbjct: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS
Sbjct: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LYHDISGDTSGDYRKILLKICGGND
Sbjct: 481 LYHDISGDTSGDYRKILLKICGGND 505
>gi|4502111 annexin VII isoform 1 [Homo sapiens]
Length = 466
Score = 432 bits (1110), Expect = e-121
Identities = 248/512 (48%), Positives = 314/512 (61%), Gaps = 57/512 (11%)
Query: 1 MSYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
MSYPGYPP YPP P PP G ++ +GQ+ Y SG
Sbjct: 1 MSYPGYPP-----------------TGYPPFPGYPPAGQESSFPPSGQY--PYPSG---- 37
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPS- 119
+P G YP VP G+ P + P P G YP PGG P + P
Sbjct: 38 -------------FPPMGGGAYPQVPSSGY--PGAGGYPAP--GGYPAPGGYPGAPQPGG 80
Query: 120 YPPYPGAPVPGQPMP-PPGQQPPGAYPGQPPVTYPGQPP-VPLPGQQQPVPSYPG----- 172
P YPG P PGQ PPG YP P +Y G P VPLPG +PG
Sbjct: 81 APSYPGVP-PGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPG------GFPGGQMPS 133
Query: 173 -YPGSGTVTPAVPPTQFG-SRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSR 230
YPG P+ P T ++GTI A FD +RDAE+LRKAMKGFGTDEQAI+D + +R
Sbjct: 134 QYPGGQPTYPSQPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANR 193
Query: 231 SNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGT 290
SN QRQ+I +FKT+YGKDLIKDLKSELSGN E+ ILAL P +D + +++A++G GT
Sbjct: 194 SNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGT 253
Query: 291 DEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDEST 350
E LIEIL +R+N+ IRE+ R Y++EF + LE+ IRSDTSGHF+RLL+S+ QGNRDE+
Sbjct: 254 QERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQ 313
Query: 351 NVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSI 410
+++ +AQ DAQ LY AGE RLGTDES FN +L +RS L A Y RM RD+ S+
Sbjct: 314 SINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSV 373
Query: 411 CREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIR 470
RE SG +E G+ +++C N PAFFAERL AM+GAGT D TL+RI+V+RSE DL+ I+
Sbjct: 374 SREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIK 433
Query: 471 SEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
+ +MY K+L I+GDTSGDYR++LL I G
Sbjct: 434 QMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVG 465
Score = 86.3 bits (212), Expect = 6e-17
Identities = 56/165 (33%), Positives = 93/165 (56%), Gaps = 9/165 (5%)
Query: 341 LSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQR 400
++QG + N D A RDA+ L A + GTDE V+ +RS + ++
Sbjct: 152 VTQGTIRPAANFD---AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKT 207
Query: 401 MTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMV 459
G+D+ K + E+SG++EE +LA+ P ++ A L KAM+GAGT++R LI I+
Sbjct: 208 SYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILC 263
Query: 460 SRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504
+R+ ++ +I Y+ +G+ L DI DTSG + ++L+ +C GN
Sbjct: 264 TRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGN 308
>gi|4809279 annexin VII isoform 2 [Homo sapiens]
Length = 488
Score = 421 bits (1082), Expect = e-118
Identities = 248/526 (47%), Positives = 307/526 (58%), Gaps = 63/526 (11%)
Query: 1 MSYPGYPP----PPGGYPPAAP--------------GGGPWGGAAYPPPPSMPPIGLDNV 42
MSYPGYPP P GYPPA G P GG AYP PS G
Sbjct: 1 MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSS---GYPGA 57
Query: 43 ATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAG----YPPVPPG-GFGQPPSAQ 97
Y GG P YPGAP G YP VPPG GFG PP
Sbjct: 58 GGYPAP-----------------GGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGG- 99
Query: 98 QPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPP 157
+ YP P P+ P PG PG Q P YPG GQP
Sbjct: 100 ---AGFSGYPQPPSQSYGGGPAQVPLPGG--------FPGGQMPSQYPG-------GQPT 141
Query: 158 VPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFG-SRGTITDAPGFDPLRDAEVLRKAMKGF 216
P SYP + + P T ++GTI A FD +RDAE+LRKAMKGF
Sbjct: 142 YPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGF 201
Query: 217 GTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLF 276
GTDEQAI+D + +RSN QRQ+I +FKT+YGKDLIKDLKSELSGN E+ ILAL P +
Sbjct: 202 GTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYY 261
Query: 277 DIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQR 336
D + +++A++G GT E LIEIL +R+N+ IRE+ R Y++EF + LE+ IRSDTSGHF+R
Sbjct: 262 DAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFER 321
Query: 337 LLISLSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFN 396
LL+S+ QGNRDE+ +++ +AQ DAQ LY AGE RLGTDES FN +L +RS L A
Sbjct: 322 LLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATME 381
Query: 397 EYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIR 456
Y RM RD+ S+ RE SG +E G+ +++C N PAFFAERL AM+GAGT D TL+R
Sbjct: 382 AYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVR 441
Query: 457 IMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICG 502
I+V+RSE DL+ I+ + +MY K+L I+GDTSGDYR++LL I G
Sbjct: 442 IVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVG 487
Score = 86.3 bits (212), Expect = 6e-17
Identities = 56/165 (33%), Positives = 93/165 (56%), Gaps = 9/165 (5%)
Query: 341 LSQGNRDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQR 400
++QG + N D A RDA+ L A + GTDE V+ +RS + ++
Sbjct: 174 VTQGTIRPAANFD---AIRDAEILRKAMKG-FGTDEQAIVDVVANRSNDQRQKIKAAFKT 229
Query: 401 MTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMV 459
G+D+ K + E+SG++EE +LA+ P ++ A L KAM+GAGT++R LI I+
Sbjct: 230 SYGKDLIKDLKSELSGNMEELILALFM----PPTYYDAWSLRKAMQGAGTQERVLIEILC 285
Query: 460 SRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504
+R+ ++ +I Y+ +G+ L DI DTSG + ++L+ +C GN
Sbjct: 286 TRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGN 330
>gi|4502105 annexin IV [Homo sapiens]
Length = 321
Score = 372 bits (955), Expect = e-103
Identities = 181/314 (57%), Positives = 243/314 (77%)
Query: 192 GTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLI 251
GT+ A GF+ + DA+ LRKAMKG GTDE AII L R+ QRQ+I ++K+ G+DLI
Sbjct: 8 GTVKAASGFNAMEDAQTLRKAMKGLGTDEDAIISVLAYRNTAQRQEIRTAYKSTIGRDLI 67
Query: 252 KDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELN 311
DLKSELSGNFE+ I+ +M VL+D+ E++ A+KG GTDE CLIEILASR+ E IR ++
Sbjct: 68 DDLKSELSGNFEQVIVGMMTPTVLYDVQELRRAMKGAGTDEGCLIEILASRTPEEIRRIS 127
Query: 312 RAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGENR 371
+ Y+ ++ ++LE+ IRSDTS FQR+L+SLS G RDE +D +L ++DAQ+LY AGE +
Sbjct: 128 QTYQQQYGRSLEDDIRSDTSFMFQRVLVSLSAGGRDEGNYLDDALVRQDAQDLYEAGEKK 187
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKN 431
GTDE KF VLCSR+R HL+ VF+EY+R++ +DIE+SI E SG E+ +LA+VKC++N
Sbjct: 188 WGTDEVKFLTVLCSRNRNHLLHVFDEYKRISQKDIEQSIKSETSGSFEDALLAIVKCMRN 247
Query: 432 TPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSG 491
A+FAE+L K+M+G GT D TLIR+MVSR+E D+LDIR+ +KR+YGKSLY I GDTSG
Sbjct: 248 KSAYFAEKLYKSMKGLGTDDNTLIRVMVSRAEIDMLDIRAHFKRLYGKSLYSFIKGDTSG 307
Query: 492 DYRKILLKICGGND 505
DYRK+LL +CGG+D
Sbjct: 308 DYRKVLLVLCGGDD 321
>gi|71773415 annexin VI isoform 2 [Homo sapiens]
Length = 667
Score = 359 bits (921), Expect = 4e-99
Identities = 182/315 (57%), Positives = 236/315 (74%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
RG+I D PGFDP +DAE L AMKGFG+D++AI+D + SRSN+QRQ++ S+K+ YGKDL
Sbjct: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
I DLK EL+G FE+ I+ LM+ P D EIK+AI G+GTDE CLIEILASR+NE + +L
Sbjct: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
AYK +++ LE I DTSGHFQ++L+ L QG R+E V L Q+D Q+LY AGE
Sbjct: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
Query: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
+ GTDE++F +L +RS+ HL VF+EY + TG+ IE SI E+SGD E+ MLAVVKC++
Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
Query: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
+TP +FAERL KAM+G GT+D TLIRIMVSRSE D+LDIR ++ Y KSLY I DTS
Sbjct: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
Query: 491 GDYRKILLKICGGND 505
G+Y+K LLK+ GG+D
Sbjct: 311 GEYKKTLLKLSGGDD 325
Score = 319 bits (817), Expect = 4e-87
Identities = 162/315 (51%), Positives = 225/315 (71%), Gaps = 1/315 (0%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
+GT+ A F+P DA+ LRKAMKG GTDE IID + RSN QRQQI +FK+ +G+DL
Sbjct: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
+ DLKSE+SG+ + IL LM P +D ++K+A++G GTDE LIEILA+R+N IR +
Sbjct: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
N AYK ++ K+LE+A+ SDTSGHF+R+LISL+ G+R+E ++ A+ DAQE+
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG-GENLDQAREDAQEIADTPSG 532
Query: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
+ E++F +LC+RS HL VF E+ +MT D+E +I +EMSGD+ + +A+V+ +K
Sbjct: 533 DKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVAIVQSVK 592
Query: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
N P FFA++L K+M+GAGT ++TL RIMVSRSE DLL+IR E+ Y KSL+ I GDTS
Sbjct: 593 NKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQAIEGDTS 652
Query: 491 GDYRKILLKICGGND 505
GD+ K LL +CGG D
Sbjct: 653 GDFLKALLALCGGED 667
Score = 145 bits (365), Expect = 1e-34
Identities = 101/323 (31%), Positives = 164/323 (50%), Gaps = 40/323 (12%)
Query: 216 FGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMK---- 271
+GTDE I LG+RS + + + + GK + ++ ELSG+FEK +LA++K
Sbjct: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
Query: 272 TPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTS 331
TP F + +A+KG+GT + LI I+ SRS + ++ ++ +++K+L I++DTS
Sbjct: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
Query: 332 GHFQRLLISLSQGNRDESTNVDMSLAQ-----------------------------RDAQ 362
G +++ L+ LS G+ D + AQ DA+
Sbjct: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
Query: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
L A + LGTDE ++ RS + ++ GRD+ + E+SGDL +
Sbjct: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLI 429
Query: 423 LAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
L L PA + A++L KAM GAGT ++ LI I+ +R+ ++ I YK Y KSL
Sbjct: 430 LG----LMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSL 485
Query: 482 YHDISGDTSGDYRKILLKICGGN 504
+S DTSG +R+IL+ + G+
Sbjct: 486 EDALSSDTSGHFRRILISLATGH 508
>gi|71773329 annexin VI isoform 1 [Homo sapiens]
Length = 673
Score = 359 bits (921), Expect = 4e-99
Identities = 182/315 (57%), Positives = 236/315 (74%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
RG+I D PGFDP +DAE L AMKGFG+D++AI+D + SRSN+QRQ++ S+K+ YGKDL
Sbjct: 11 RGSIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDL 70
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
I DLK EL+G FE+ I+ LM+ P D EIK+AI G+GTDE CLIEILASR+NE + +L
Sbjct: 71 IADLKYELTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQL 130
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
AYK +++ LE I DTSGHFQ++L+ L QG R+E V L Q+D Q+LY AGE
Sbjct: 131 VAAYKDAYERDLEADIIGDTSGHFQKMLVVLLQGTREEDDVVSEDLVQQDVQDLYEAGEL 190
Query: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
+ GTDE++F +L +RS+ HL VF+EY + TG+ IE SI E+SGD E+ MLAVVKC++
Sbjct: 191 KWGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIR 250
Query: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
+TP +FAERL KAM+G GT+D TLIRIMVSRSE D+LDIR ++ Y KSLY I DTS
Sbjct: 251 STPEYFAERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
Query: 491 GDYRKILLKICGGND 505
G+Y+K LLK+ GG+D
Sbjct: 311 GEYKKTLLKLSGGDD 325
Score = 313 bits (803), Expect = 2e-85
Identities = 163/321 (50%), Positives = 226/321 (70%), Gaps = 7/321 (2%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
+GT+ A F+P DA+ LRKAMKG GTDE IID + RSN QRQQI +FK+ +G+DL
Sbjct: 354 KGTVRPANDFNPDADAKALRKAMKGLGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDL 413
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
+ DLKSE+SG+ + IL LM P +D ++K+A++G GTDE LIEILA+R+N IR +
Sbjct: 414 MTDLKSEISGDLARLILGLMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAI 473
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ---ELYAA 367
N AYK ++ K+LE+A+ SDTSGHF+R+LISL+ G+R+E ++ A+ DAQ E+
Sbjct: 474 NEAYKEDYHKSLEDALSSDTSGHFRRILISLATGHREEG-GENLDQAREDAQVAAEILEI 532
Query: 368 GENRLGTD---ESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLA 424
+ G E++F +LC+RS HL VF E+ +MT D+E +I +EMSGD+ + +A
Sbjct: 533 ADTPSGDKTSLETRFMTILCTRSYPHLRRVFQEFIKMTNYDVEHTIKKEMSGDVRDAFVA 592
Query: 425 VVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHD 484
+V+ +KN P FFA++L K+M+GAGT ++TL RIMVSRSE DLL+IR E+ Y KSL+
Sbjct: 593 IVQSVKNKPLFFADKLYKSMKGAGTDEKTLTRIMVSRSEIDLLNIRREFIEKYDKSLHQA 652
Query: 485 ISGDTSGDYRKILLKICGGND 505
I GDTSGD+ K LL +CGG D
Sbjct: 653 IEGDTSGDFLKALLALCGGED 673
Score = 145 bits (365), Expect = 1e-34
Identities = 101/323 (31%), Positives = 164/323 (50%), Gaps = 40/323 (12%)
Query: 216 FGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMK---- 271
+GTDE I LG+RS + + + + GK + ++ ELSG+FEK +LA++K
Sbjct: 192 WGTDEAQFIYILGNRSKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRS 251
Query: 272 TPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTS 331
TP F + +A+KG+GT + LI I+ SRS + ++ ++ +++K+L I++DTS
Sbjct: 252 TPEYF-AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREIFRTKYEKSLYSMIKNDTS 310
Query: 332 GHFQRLLISLSQGNRDESTNVDMSLAQ-----------------------------RDAQ 362
G +++ L+ LS G+ D + AQ DA+
Sbjct: 311 GEYKKTLLKLSGGDDDAAGQFFPEAAQVAYQMWELSAVARVELKGTVRPANDFNPDADAK 370
Query: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
L A + LGTDE ++ RS + ++ GRD+ + E+SGDL +
Sbjct: 371 ALRKAMKG-LGTDEDTIIDIITHRSNVQRQQIRQTFKSHFGRDLMTDLKSEISGDLARLI 429
Query: 423 LAVVKCLKNTPAFF-AERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
L L PA + A++L KAM GAGT ++ LI I+ +R+ ++ I YK Y KSL
Sbjct: 430 LG----LMMPPAHYDAKQLKKAMEGAGTDEKALIEILATRTNAEIRAINEAYKEDYHKSL 485
Query: 482 YHDISGDTSGDYRKILLKICGGN 504
+S DTSG +R+IL+ + G+
Sbjct: 486 EDALSSDTSGHFRRILISLATGH 508
>gi|4502107 annexin 5 [Homo sapiens]
Length = 320
Score = 337 bits (865), Expect = 1e-92
Identities = 169/315 (53%), Positives = 230/315 (73%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
RGT+TD PGFD DAE LRKAMKG GTDE++I+ L SRSN QRQ+I +FKT +G+DL
Sbjct: 6 RGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDL 65
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
+ DLKSEL+G FEK I+ALMK L+D YE+K A+KG GT+E L EI+ASR+ E +R +
Sbjct: 66 LDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAI 125
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
+ Y+ E+ +LE+ + DTSG++QR+L+ L Q NRD +D + ++DAQ L+ AGE
Sbjct: 126 KQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGEL 185
Query: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
+ GTDE KF + +RS +HL VF++Y ++G IE++I RE SG+LE+ +LAVVK ++
Sbjct: 186 KWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIR 245
Query: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
+ PA+ AE L AM+GAGT D TLIR+MVSRSE DL +IR E+++ + SLY I GDTS
Sbjct: 246 SIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTS 305
Query: 491 GDYRKILLKICGGND 505
GDY+K LL +CG +D
Sbjct: 306 GDYKKALLLLCGEDD 320
>gi|4826643 annexin A3 [Homo sapiens]
Length = 323
Score = 332 bits (850), Expect = 6e-91
Identities = 166/317 (52%), Positives = 230/317 (72%)
Query: 189 GSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGK 248
G RGT+ D P F P DAE ++KA++G GTDE+ +I L RSN QRQ I+ ++ AYGK
Sbjct: 7 GHRGTVRDYPDFSPSVDAEAIQKAIRGIGTDEKMLISILTERSNAQRQLIVKEYQAAYGK 66
Query: 249 DLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIR 308
+L DLK +LSG+FE ++AL+ P +FD ++K+++KG GT+E LIEIL +R++ ++
Sbjct: 67 ELKDDLKGDLSGHFEHLMVALVTPPAVFDAKQLKKSMKGAGTNEDALIEILTTRTSRQMK 126
Query: 309 ELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAG 368
++++AY +KK+L + I S+TSG F++ L++L+ G RDES VD LA++DAQ LY AG
Sbjct: 127 DISQAYYTVYKKSLGDDISSETSGDFRKALLTLADGRRDESLKVDEHLAKQDAQILYKAG 186
Query: 369 ENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKC 428
ENR GTDE KF +LC RS L F+EY+ ++ +DI SI E+SG E+ +LA+V C
Sbjct: 187 ENRWGTDEDKFTEILCLRSFPQLKLTFDEYRNISQKDIVDSIKGELSGHFEDLLLAIVNC 246
Query: 429 LKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGD 488
++NTPAF AERL++A++G GT + TL RIMVSRSE DLLDIR+E+K+ YG SLY I D
Sbjct: 247 VRNTPAFLAERLHRALKGIGTDEFTLNRIMVSRSEIDLLDIRTEFKKHYGYSLYSAIKSD 306
Query: 489 TSGDYRKILLKICGGND 505
TSGDY LLKICGG+D
Sbjct: 307 TSGDYEITLLKICGGDD 323
>gi|91807122 annexin A8L2 [Homo sapiens]
Length = 327
Score = 322 bits (826), Expect = 4e-88
Identities = 170/313 (54%), Positives = 225/313 (71%), Gaps = 1/313 (0%)
Query: 193 TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIK 252
T+ + F+P DAE L KAMKG GT+EQAIID L RSN QRQQI SFK +GKDL +
Sbjct: 14 TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73
Query: 253 DLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNR 312
LKSELSG FE+ I+ALM P ++ E+ +A+KG+GT E +IEILASR+ +RE+ +
Sbjct: 74 TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDE-STNVDMSLAQRDAQELYAAGENR 371
AY+ ++ +LEE I++DTSG+ +R+L+ L QG+RD+ S+ VD +LA +DAQ+LYAAGEN
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPALALQDAQDLYAAGENI 193
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKN 431
GTDE KF +LC+RS HL+ VF EY+++ + IE SI E G LEE ML VVKC +N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253
Query: 432 TPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSG 491
++FAERL AM+GAGT+D TLIR +VSRSE DL I+ +K+MYGK+L I DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313
Query: 492 DYRKILLKICGGN 504
DY+ LL + G +
Sbjct: 314 DYKNALLSLVGSD 326
>gi|91823262 annexin A8 [Homo sapiens]
Length = 327
Score = 320 bits (819), Expect = 2e-87
Identities = 169/313 (53%), Positives = 223/313 (71%), Gaps = 1/313 (0%)
Query: 193 TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIK 252
T+ + F+P DAE L KAMKG GT+EQAIID L RSN QRQQI SFK +GKDL +
Sbjct: 14 TVKSSSHFNPDPDAETLYKAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73
Query: 253 DLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNR 312
LKSELSG FE+ I+ALM P ++ E+ +A+KG+GT E +IEILASR+ +RE+ +
Sbjct: 74 TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDE-STNVDMSLAQRDAQELYAAGENR 371
AY+ ++ +LEE I++DTSG+ +R+L+ L QG+RD+ S+ VD LA +DAQ+LYAAGE
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKI 193
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKN 431
GTDE KF +LC+RS HL+ VF EY+++ + IE SI E G LEE ML VVKC +N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253
Query: 432 TPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSG 491
++FAERL AM+GAGT+D TLIR +VSRSE DL I+ +K+MYGK+L I DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313
Query: 492 DYRKILLKICGGN 504
DY+ LL + G +
Sbjct: 314 DYKNALLSLVGSD 326
>gi|149588958 annexin A8-like 1 [Homo sapiens]
Length = 327
Score = 318 bits (815), Expect = 7e-87
Identities = 168/313 (53%), Positives = 223/313 (71%), Gaps = 1/313 (0%)
Query: 193 TITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIK 252
T+ + F+P DAE L +AMKG GT+EQAIID L RSN QRQQI SFK +GKDL +
Sbjct: 14 TVKSSSHFNPDPDAETLYQAMKGIGTNEQAIIDVLTKRSNTQRQQIAKSFKAQFGKDLTE 73
Query: 253 DLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNR 312
LKSELSG FE+ I+ALM P ++ E+ +A+KG+GT E +IEILASR+ +RE+ +
Sbjct: 74 TLKSELSGKFERLIVALMYPPYRYEAKELHDAMKGLGTKEGVIIEILASRTKNQLREIMK 133
Query: 313 AYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDE-STNVDMSLAQRDAQELYAAGENR 371
AY+ ++ +LEE I++DTSG+ +R+L+ L QG+RD+ S+ VD LA +DAQ+LYAAGE
Sbjct: 134 AYEEDYGSSLEEDIQADTSGYLERILVCLLQGSRDDVSSFVDPGLALQDAQDLYAAGEKI 193
Query: 372 LGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKN 431
GTDE KF +LC+RS HL+ VF EY+++ + IE SI E G LEE ML VVKC +N
Sbjct: 194 RGTDEMKFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQN 253
Query: 432 TPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSG 491
++FAERL AM+GAGT+D TLIR +VSRSE DL I+ +K+MYGK+L I DTSG
Sbjct: 254 LHSYFAERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMIMEDTSG 313
Query: 492 DYRKILLKICGGN 504
DY+ LL + G +
Sbjct: 314 DYKNALLSLVGSD 326
>gi|4757756 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 295 bits (754), Expect = 9e-80
Identities = 155/325 (47%), Positives = 221/325 (68%), Gaps = 4/325 (1%)
Query: 182 AVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLS 241
+ PP+ +GS T+ FD RDA + A+K G DE I++ L +RSN QRQ I +
Sbjct: 18 STPPSAYGSVKAYTN---FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFA 74
Query: 242 FKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILAS 301
++ K+L LKS LSG+ E IL L+KTP +D E+K ++KG+GTDE LIEI+ S
Sbjct: 75 YQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICS 134
Query: 302 RSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV-DMSLAQRD 360
R+N+ ++E+NR YK +K LE+ I SDTSG F++L+++L++G R E +V D L +D
Sbjct: 135 RTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQD 194
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
A++LY AG R GTD K+ +++ RS HL VF+ Y+ + D+ +SI +E+ GDLE
Sbjct: 195 ARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
L +V+C++N P +FA+RL +M+G GT+D+ LIRIMVSRSE D+L IRSE+KR YGKS
Sbjct: 255 AFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LY+ I DT GDY+K LL +CGG+D
Sbjct: 315 LYYYIQQDTKGDYQKALLYLCGGDD 339
>gi|50845386 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 295 bits (754), Expect = 9e-80
Identities = 155/325 (47%), Positives = 221/325 (68%), Gaps = 4/325 (1%)
Query: 182 AVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLS 241
+ PP+ +GS T+ FD RDA + A+K G DE I++ L +RSN QRQ I +
Sbjct: 18 STPPSAYGSVKAYTN---FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFA 74
Query: 242 FKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILAS 301
++ K+L LKS LSG+ E IL L+KTP +D E+K ++KG+GTDE LIEI+ S
Sbjct: 75 YQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICS 134
Query: 302 RSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV-DMSLAQRD 360
R+N+ ++E+NR YK +K LE+ I SDTSG F++L+++L++G R E +V D L +D
Sbjct: 135 RTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQD 194
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
A++LY AG R GTD K+ +++ RS HL VF+ Y+ + D+ +SI +E+ GDLE
Sbjct: 195 ARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
L +V+C++N P +FA+RL +M+G GT+D+ LIRIMVSRSE D+L IRSE+KR YGKS
Sbjct: 255 AFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LY+ I DT GDY+K LL +CGG+D
Sbjct: 315 LYYYIQQDTKGDYQKALLYLCGGDD 339
>gi|50845388 annexin A2 isoform 1 [Homo sapiens]
Length = 357
Score = 295 bits (754), Expect = 9e-80
Identities = 155/325 (47%), Positives = 221/325 (68%), Gaps = 4/325 (1%)
Query: 182 AVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLS 241
+ PP+ +GS T+ FD RDA + A+K G DE I++ L +RSN QRQ I +
Sbjct: 36 STPPSAYGSVKAYTN---FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFA 92
Query: 242 FKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILAS 301
++ K+L LKS LSG+ E IL L+KTP +D E+K ++KG+GTDE LIEI+ S
Sbjct: 93 YQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICS 152
Query: 302 RSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV-DMSLAQRD 360
R+N+ ++E+NR YK +K LE+ I SDTSG F++L+++L++G R E +V D L +D
Sbjct: 153 RTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQD 212
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
A++LY AG R GTD K+ +++ RS HL VF+ Y+ + D+ +SI +E+ GDLE
Sbjct: 213 ARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 272
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
L +V+C++N P +FA+RL +M+G GT+D+ LIRIMVSRSE D+L IRSE+KR YGKS
Sbjct: 273 AFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 332
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LY+ I DT GDY+K LL +CGG+D
Sbjct: 333 LYYYIQQDTKGDYQKALLYLCGGDD 357
>gi|209862831 annexin A2 isoform 2 [Homo sapiens]
Length = 339
Score = 295 bits (754), Expect = 9e-80
Identities = 155/325 (47%), Positives = 221/325 (68%), Gaps = 4/325 (1%)
Query: 182 AVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLS 241
+ PP+ +GS T+ FD RDA + A+K G DE I++ L +RSN QRQ I +
Sbjct: 18 STPPSAYGSVKAYTN---FDAERDALNIETAIKTKGVDEVTIVNILTNRSNAQRQDIAFA 74
Query: 242 FKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILAS 301
++ K+L LKS LSG+ E IL L+KTP +D E+K ++KG+GTDE LIEI+ S
Sbjct: 75 YQRRTKKELASALKSALSGHLETVILGLLKTPAQYDASELKASMKGLGTDEDSLIEIICS 134
Query: 302 RSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV-DMSLAQRD 360
R+N+ ++E+NR YK +K LE+ I SDTSG F++L+++L++G R E +V D L +D
Sbjct: 135 RTNQELQEINRVYKEMYKTDLEKDIISDTSGDFRKLMVALAKGRRAEDGSVIDYELIDQD 194
Query: 361 AQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEE 420
A++LY AG R GTD K+ +++ RS HL VF+ Y+ + D+ +SI +E+ GDLE
Sbjct: 195 ARDLYDAGVKRKGTDVPKWISIMTERSVPHLQKVFDRYKSYSPYDMLESIRKEVKGDLEN 254
Query: 421 GMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKS 480
L +V+C++N P +FA+RL +M+G GT+D+ LIRIMVSRSE D+L IRSE+KR YGKS
Sbjct: 255 AFLNLVQCIQNKPLYFADRLYDSMKGKGTRDKVLIRIMVSRSEVDMLKIRSEFKRKYGKS 314
Query: 481 LYHDISGDTSGDYRKILLKICGGND 505
LY+ I DT GDY+K LL +CGG+D
Sbjct: 315 LYYYIQQDTKGDYQKALLYLCGGDD 339
>gi|4502101 annexin I [Homo sapiens]
Length = 346
Score = 294 bits (752), Expect = 1e-79
Identities = 153/322 (47%), Positives = 214/322 (66%)
Query: 183 VPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSF 242
V ++ G ++ P F+P D L KA+ G DE IID L R+N QRQQI ++
Sbjct: 25 VKSSKGGPGSAVSPYPTFNPSSDVAALHKAIMVKGVDEATIIDILTKRNNAQRQQIKAAY 84
Query: 243 KTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASR 302
GK L + LK L+G+ E+ +LAL+KTP FD E++ A+KG+GTDE LIEILASR
Sbjct: 85 LQETGKPLDETLKKALTGHLEEVVLALLKTPAQFDADELRAAMKGLGTDEDTLIEILASR 144
Query: 303 SNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQ 362
+N+ IR++NR Y+ E K+ L + I SDTSG F+ L+SL++G+R E V+ LA DA+
Sbjct: 145 TNKEIRDINRVYREELKRDLAKDITSDTSGDFRNALLSLAKGDRSEDFGVNEDLADSDAR 204
Query: 363 ELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGM 422
LY AGE R GTD + FN +L +RS L VF +Y + + D+ K + E+ GD+E+ +
Sbjct: 205 ALYEAGERRKGTDVNVFNTILTTRSYPQLRRVFQKYTKYSKHDMNKVLDLELKGDIEKCL 264
Query: 423 LAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLY 482
A+VKC + PAFFAE+L++AM+G GT+ + LIRIMVSRSE D+ DI++ Y++MYG SL
Sbjct: 265 TAIVKCATSKPAFFAEKLHQAMKGVGTRHKALIRIMVSRSEIDMNDIKAFYQKMYGISLC 324
Query: 483 HDISGDTSGDYRKILLKICGGN 504
I +T GDY KIL+ +CGGN
Sbjct: 325 QAILDETKGDYEKILVALCGGN 346
>gi|51896029 annexin A13 isoform b [Homo sapiens]
Length = 357
Score = 291 bits (745), Expect = 9e-79
Identities = 155/335 (46%), Positives = 222/335 (66%), Gaps = 9/335 (2%)
Query: 175 GSGTVTPAVPPTQFGSRGTITDAP---------GFDPLRDAEVLRKAMKGFGTDEQAIID 225
G + V P SR +AP GFD RDA+ L KA KG GT+E AII+
Sbjct: 21 GDSQPSTVVQPLSHPSRNGEPEAPQPAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIE 80
Query: 226 CLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAI 285
L R++ +RQQI +K YGK+L + LKSELSGNFEKT LAL+ P + ++++A+
Sbjct: 81 ILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAM 140
Query: 286 KGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGN 345
KG+GTDE+ LIE+L +R+N+ I + AY+ F ++LE ++ DTSG+ +++L+SL Q N
Sbjct: 141 KGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 200
Query: 346 RDESTNVDMSLAQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRD 405
R+E +VD LA +DA++LY AGE R GTDE FN VL RS L A F YQ + G+D
Sbjct: 201 RNEGDDVDKDLAGQDAKDLYDAGEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKD 260
Query: 406 IEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETD 465
IE++I E SGDL++ L +V+C ++ +FAERL K+M+GAGT + TLIRI+V+R+E D
Sbjct: 261 IEEAIEEETSGDLQKAYLTLVRCAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVD 320
Query: 466 LLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
L I+++++ Y KSL + DTSGD+RK+L+ +
Sbjct: 321 LQGIKAKFQEKYQKSLSDMVRSDTSGDFRKLLVAL 355
Score = 86.3 bits (212), Expect = 6e-17
Identities = 46/146 (31%), Positives = 87/146 (59%), Gaps = 4/146 (2%)
Query: 359 RDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDL 418
RDA++L A + +GT+E+ +L R+ + +Y+ G+++E+ + E+SG+
Sbjct: 59 RDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATYGKELEEVLKSELSGNF 117
Query: 419 EEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYG 478
E+ LA+ L + A +L KAM+G GT + LI ++ +R+ +++ I+ Y+R++
Sbjct: 118 EKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEIIAIKEAYQRLFD 174
Query: 479 KSLYHDISGDTSGDYRKILLKICGGN 504
+SL D+ GDTSG+ +KIL+ + N
Sbjct: 175 RSLESDVKGDTSGNLKKILVSLLQAN 200
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
AE L K+MKG GTDE+ +I + +R+ Q I F+ Y K L ++S+ SG+F K
Sbjct: 292 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 351
Query: 266 ILALM 270
++AL+
Sbjct: 352 LVALL 356
>gi|51895795 annexin A13 isoform a [Homo sapiens]
Length = 316
Score = 290 bits (743), Expect = 2e-78
Identities = 151/313 (48%), Positives = 218/313 (69%), Gaps = 1/313 (0%)
Query: 189 GSRGTITDAP-GFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYG 247
G+R +P GFD RDA+ L KA KG GT+E AII+ L R++ +RQQI +K YG
Sbjct: 2 GNRHAKASSPQGFDVDRDAKKLNKACKGMGTNEAAIIEILSGRTSDERQQIKQKYKATYG 61
Query: 248 KDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHI 307
K+L + LKSELSGNFEKT LAL+ P + ++++A+KG+GTDE+ LIE+L +R+N+ I
Sbjct: 62 KELEEVLKSELSGNFEKTALALLDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRTNKEI 121
Query: 308 RELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAA 367
+ AY+ F ++LE ++ DTSG+ +++L+SL Q NR+E +VD LA +DA++LY A
Sbjct: 122 IAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQANRNEGDDVDKDLAGQDAKDLYDA 181
Query: 368 GENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVK 427
GE R GTDE FN VL RS L A F YQ + G+DIE++I E SGDL++ L +V+
Sbjct: 182 GEGRWGTDELAFNEVLAKRSYKQLRATFQAYQILIGKDIEEAIEEETSGDLQKAYLTLVR 241
Query: 428 CLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISG 487
C ++ +FAERL K+M+GAGT + TLIRI+V+R+E DL I+++++ Y KSL +
Sbjct: 242 CAQDCEDYFAERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRS 301
Query: 488 DTSGDYRKILLKI 500
DTSGD+RK+L+ +
Sbjct: 302 DTSGDFRKLLVAL 314
Score = 86.7 bits (213), Expect = 5e-17
Identities = 49/162 (30%), Positives = 91/162 (56%), Gaps = 5/162 (3%)
Query: 344 GNRDESTNVDMSL-AQRDAQELYAAGENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMT 402
GNR + RDA++L A + +GT+E+ +L R+ + +Y+
Sbjct: 2 GNRHAKASSPQGFDVDRDAKKLNKACKG-MGTNEAAIIEILSGRTSDERQQIKQKYKATY 60
Query: 403 GRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRS 462
G+++E+ + E+SG+ E+ LA+ L + A +L KAM+G GT + LI ++ +R+
Sbjct: 61 GKELEEVLKSELSGNFEKTALAL---LDRPSEYAARQLQKAMKGLGTDESVLIEVLCTRT 117
Query: 463 ETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKICGGN 504
+++ I+ Y+R++ +SL D+ GDTSG+ +KIL+ + N
Sbjct: 118 NKEIIAIKEAYQRLFDRSLESDVKGDTSGNLKKILVSLLQAN 159
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/65 (40%), Positives = 40/65 (61%)
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKT 265
AE L K+MKG GTDE+ +I + +R+ Q I F+ Y K L ++S+ SG+F K
Sbjct: 251 AERLYKSMKGAGTDEETLIRIVVTRAEVDLQGIKAKFQEKYQKSLSDMVRSDTSGDFRKL 310
Query: 266 ILALM 270
++AL+
Sbjct: 311 LVALL 315
>gi|48762937 annexin A10 [Homo sapiens]
Length = 324
Score = 262 bits (670), Expect = 5e-70
Identities = 134/314 (42%), Positives = 205/314 (65%), Gaps = 1/314 (0%)
Query: 191 RGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
+GTI AP F+P+ DA++L A++GF D+ +I+ L R N QR I ++++ YG+DL
Sbjct: 8 QGTIFPAPNFNPIMDAQMLGGALQGFDCDKDMLINILTQRCNAQRMMIAEAYQSMYGRDL 67
Query: 251 IKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIREL 310
I D++ +LS +F+ + LM P L+D +E+ A+KGVGTDE CLIEILASR+N I ++
Sbjct: 68 IGDMREQLSDHFKDVMAGLMYPPPLYDAHELWHAMKGVGTDENCLIEILASRTNGEIFQM 127
Query: 311 NRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNVDMSLAQRDAQELYAAGEN 370
AY ++ L+E I S+TSGHF+ L++L QG R+E D ++A +DA L+ A +
Sbjct: 128 REAYCLQYSNNLQEDIYSETSGHFRDTLMNLVQGTREEG-YTDPAMAAQDAMVLWEACQQ 186
Query: 371 RLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLK 430
+ G ++ +LC++S L VF E+Q ++G+D+ +I G +E ++A+V C++
Sbjct: 187 KTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYFQELLVAIVLCVR 246
Query: 431 NTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTS 490
+ PA+FA RL A+ G ++T+IRI+++RSE DLL IR YK YGKSL+HDI S
Sbjct: 247 DKPAYFAYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERYGKSLFHDIRNFAS 306
Query: 491 GDYRKILLKICGGN 504
G Y+K LL IC G+
Sbjct: 307 GHYKKALLAICAGD 320
Score = 54.7 bits (130), Expect = 2e-07
Identities = 36/150 (24%), Positives = 77/150 (51%), Gaps = 6/150 (4%)
Query: 204 RDAEVLRKAMKGFGTDEQAIIDC-LGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNF 262
+DA VL +A + + + ++ L ++S +Q + + F+ G+D++ + G F
Sbjct: 175 QDAMVLWEACQQKTGEHKTMLQMILCNKSYQQLRLVFQEFQNISGQDMVDAINECYDGYF 234
Query: 263 EKTILALM----KTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEF 318
++ ++A++ P F Y + AI G +I IL +RS + + + YK +
Sbjct: 235 QELLVAIVLCVRDKPAYF-AYRLYSAIHDFGFHNKTVIRILIARSEIDLLTIRKRYKERY 293
Query: 319 KKTLEEAIRSDTSGHFQRLLISLSQGNRDE 348
K+L IR+ SGH+++ L+++ G+ ++
Sbjct: 294 GKSLFHDIRNFASGHYKKALLAICAGDAED 323
>gi|145864465 annexin A9 [Homo sapiens]
Length = 345
Score = 213 bits (543), Expect = 3e-55
Identities = 118/320 (36%), Positives = 193/320 (60%), Gaps = 6/320 (1%)
Query: 188 FGSRGTITDAPGFDPLRDAEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYG 247
+G+ GT+ F +DA+ L +A+ G G D AI+D L +RS +QRQ I +F+
Sbjct: 29 WGTLGTLRTFLNFSVDKDAQRLLRAITGQGVDRSAIVDVLTNRSREQRQLISRNFQERTQ 88
Query: 248 KDLIKDLKSELSGNFEKTILALMKTPVLFDIYEIKEAIKGVGTDEACLIEILASRSNEHI 307
+DL+K L++ LSGN E+ ++AL++ FD E++ A+K + IEILA+R+ +
Sbjct: 89 QDLMKSLQAALSGNLERIVMALLQPTAQFDAQELRTALKASDSAVDVAIEILATRTPPQL 148
Query: 308 RELNRAYKAEFKKTLEEAIRSDTSGHFQRLLISLSQGNRDESTNV-DMSLAQRDAQELYA 366
+E YK F+ + I S+TSG Q LL++L++G RD + + D +LA++D Q L
Sbjct: 149 QECLAVYKHNFQVEAVDDITSETSGILQDLLLALAKGGRDSYSGIIDYNLAEQDVQALQR 208
Query: 367 A-GENRLGTDESKFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAV 425
A G +R E + V R+ HL+ VF++YQR TG+++E+++ GD + +L +
Sbjct: 209 AEGPSR----EETWVPVFTQRNPEHLIRVFDQYQRSTGQELEEAVQNRFHGDAQVALLGL 264
Query: 426 VKCLKNTPAFFAERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSLYHDI 485
+KNTP +FA++L++A++ + LIRI++SR ETDLL IR+E+++ +GKSLY +
Sbjct: 265 ASVIKNTPLYFADKLHQALQETEPNYQVLIRILISRCETDLLSIRAEFRKKFGKSLYSSL 324
Query: 486 SGDTSGDYRKILLKICGGND 505
GD + LL +C D
Sbjct: 325 QDAVKGDCQSALLALCRAED 344
>gi|239752501 PREDICTED: hypothetical protein XP_002347094 [Homo
sapiens]
Length = 112
Score = 115 bits (288), Expect = 9e-26
Identities = 58/104 (55%), Positives = 75/104 (72%)
Query: 378 KFNAVLCSRSRAHLVAVFNEYQRMTGRDIEKSICREMSGDLEEGMLAVVKCLKNTPAFFA 437
KF +LC+RS HL+ VF EY+++ + IE SI E G LEE ML VVKC +N ++FA
Sbjct: 2 KFITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFA 61
Query: 438 ERLNKAMRGAGTKDRTLIRIMVSRSETDLLDIRSEYKRMYGKSL 481
ERL AM+GAGT+D TLIR +VSRSE DL I+ +K+MYGK+L
Sbjct: 62 ERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTL 105
Score = 39.7 bits (91), Expect = 0.006
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 3/106 (2%)
Query: 224 IDCLGSRSNKQRQQILLSFKTAYGKDLIKDLKSELSGNFEKTILALMKTPVLFDIY---E 280
I L +RS ++ ++ K + +KSE G+ E+ +L ++K Y
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTVVKCTQNLHSYFAER 63
Query: 281 IKEAIKGVGTDEACLIEILASRSNEHIRELNRAYKAEFKKTLEEAI 326
+ A+KG GT + LI + SRS + + +K + KTL I
Sbjct: 64 LYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTLSSMI 109
Score = 32.3 bits (72), Expect = 1.0
Identities = 15/46 (32%), Positives = 26/46 (56%)
Query: 455 IRIMVSRSETDLLDIRSEYKRMYGKSLYHDISGDTSGDYRKILLKI 500
I I+ +RS T LL + EY+++ KS+ I +T G + +L +
Sbjct: 4 ITILCTRSATHLLRVFEEYEKIANKSIEDSIKSETHGSLEEAMLTV 49
Score = 31.2 bits (69), Expect = 2.3
Identities = 20/45 (44%), Positives = 23/45 (51%)
Query: 206 AEVLRKAMKGFGTDEQAIIDCLGSRSNKQRQQILLSFKTAYGKDL 250
AE L AMKG GT + +I + SRS I FK YGK L
Sbjct: 61 AERLYYAMKGAGTRDGTLIRNIVSRSEIDLNLIKCHFKKMYGKTL 105
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 95.5 bits (236), Expect = 1e-19
Identities = 77/199 (38%), Positives = 89/199 (44%), Gaps = 27/199 (13%)
Query: 7 PPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATY--AGQFNQDYLSGMAANMSGT 64
PPP G P P GA PPPP +P G+ + AG L G A
Sbjct: 899 PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPP 958
Query: 65 FGGANMPNLYPGAPGAGYPPVPP-GGFGQPPSAQQPVPPYGMYPPP----GGNPP----- 114
GA +P L P PGAG PP PP G G PP P+P G+ PPP G PP
Sbjct: 959 LPGAGIP-LPPPLPGAGIPPPPPLPGAGIPPPP--PLPGAGIPPPPPLPGAGIPPPPPLP 1015
Query: 115 -SRMPSYPPYPGA------PVPGQPMPPPGQQPPGAYPGQPPVTYPG-QPPVPLPGQQQP 166
+ +P PP PGA P+PG +PPP P P PP+ G PP PLPG P
Sbjct: 1016 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1075
Query: 167 VPSYPGYPGSGTVTPAVPP 185
P P PG+G P PP
Sbjct: 1076 PP--PPLPGAG--IPPPPP 1090
Score = 95.5 bits (236), Expect = 1e-19
Identities = 76/198 (38%), Positives = 87/198 (43%), Gaps = 33/198 (16%)
Query: 4 PGYPPPPGGY---PPAAPGGG-----PWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLS 55
P PP PG PP PG G P GA PPPP +P G+ L
Sbjct: 943 PPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPP---------LP 993
Query: 56 GMAANMSGTFGGANMPNLYPGAPGAGYPPVPP-GGFGQPPSAQQPVPPYGMYPPPGGNPP 114
G GA +P P PGAG PP PP G G PP P+P G+ PPP P
Sbjct: 994 GAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPP--PLPGAGI-PPPPPLPG 1049
Query: 115 SRMPSYPPYPGA------PVPGQPMPPPGQQPPGAYPGQPPVTYPG-QPPVPLPGQQQPV 167
+ +P PP PGA P+PG +PPP P P PP+ G PP PLPG P
Sbjct: 1050 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1109
Query: 168 PSYPGYPGSGTVTPAVPP 185
P P PG+G P PP
Sbjct: 1110 P--PPLPGAG--IPPPPP 1123
Score = 90.5 bits (223), Expect = 3e-18
Identities = 76/211 (36%), Positives = 90/211 (42%), Gaps = 41/211 (19%)
Query: 5 GYPPPP----GGYPPAAP--GGG-----PWGGAAYPPPPSMPPIGLDNVATY--AGQFNQ 51
G PPPP G PP P G G P GA PPPP +P G+ AG
Sbjct: 1040 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1099
Query: 52 DYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPP-GGFGQPPSAQQPVPPYGMYPPP- 109
L G+ GA +P P PGAG PP PP G G PP P+P G+ PPP
Sbjct: 1100 PPLPGVGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGAGIPPPP--PLPRVGIPPPPP 1156
Query: 110 ---GGNPP------SRMPSYPPYPGA------PVPGQPMPPPGQQPPGAYPGQPPVTYPG 154
G PP + +P PP PG P+PG +PPP P P PP+ G
Sbjct: 1157 LPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMG 1216
Query: 155 QPPVPLPGQQQPVPSYPGYPGSGTVTPAVPP 185
PP P P P+P PG+G P + P
Sbjct: 1217 IPPAPAP----PLPP----PGTGIPPPPLLP 1239
Score = 79.7 bits (195), Expect = 6e-15
Identities = 76/205 (37%), Positives = 87/205 (42%), Gaps = 34/205 (16%)
Query: 5 GYPPPP----GGYPPAAP--GGG-----PWGGAAYPPPPSMPPIGLDNVATY--AGQFNQ 51
G PPPP G PP P G G P GA PPPP +P +G+ AG
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPP 1121
Query: 52 DYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPP-GGFGQPPSAQQPVPPYGMYPPP- 109
L G GA +P P P G PP PP G G PP P+P G+ PPP
Sbjct: 1122 PPLPGAGIPPPPPLPGAGIPPP-PPLPRVGIPPPPPLPGAGIPPPP--PLPGAGIPPPPP 1178
Query: 110 ----GGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQ 165
G PP +P P P+PG +PPP PP G PP PP+P PG
Sbjct: 1179 LPGVGIPPPPPLPGVGIPPPPPLPGAGIPPP---PPLPGMGIPPAP---APPLPPPGTGI 1232
Query: 166 PVPSYPGYPGSGTVTPAVPPTQFGS 190
P P P P SG P +P Q GS
Sbjct: 1233 PPP--PLLPVSG--PPLLP--QVGS 1251
Score = 77.0 bits (188), Expect = 4e-14
Identities = 69/203 (33%), Positives = 82/203 (40%), Gaps = 53/203 (26%)
Query: 5 GYPPPP----GGYPPAAP--GGG-----PWGGAAYPPPPSMPPIGLDNVATYAGQFNQDY 53
G PPPP G PP P G G P GA PPPP +P +G+ G
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPG------ 1159
Query: 54 LSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPP-GGFGQPPSAQQPVPPYGMYPPPGGN 112
G P P PGAG PP PP G G PP P+P G+ PPP
Sbjct: 1160 ------------AGIPPP---PPLPGAGIPPPPPLPGVGIPPPP--PLPGVGI-PPPPPL 1201
Query: 113 PPSRMPSYPPYPG-----APVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQ-P 166
P + +P PP PG AP P P+PPPG P P + G P +P G P
Sbjct: 1202 PGAGIPPPPPLPGMGIPPAPAP--PLPPPGT----GIPPPPLLPVSGPPLLPQVGSSTLP 1255
Query: 167 VPSYPGYPGSGTVTPAVPPTQFG 189
P G+ + P +P FG
Sbjct: 1256 TPQVCGF-----LPPPLPSGLFG 1273
Score = 69.7 bits (169), Expect = 6e-12
Identities = 61/194 (31%), Positives = 78/194 (40%), Gaps = 27/194 (13%)
Query: 7 PPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66
PPPP +A G P + PP + + + F + T
Sbjct: 810 PPPPPSLLWSAGQGQP---GSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
Query: 67 GANMPNLY------PGAPGAGYPPVPPGGFGQPPSAQ--QPVPPYGMYPPPGGNPPSRMP 118
++MP L P PG P +P QPP Q + +P PPP P + +P
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLP-----PPPPPLPGAGIP 921
Query: 119 SYPPYPGA------PVPGQPMPPPGQQPPGAYPGQPPVTYPGQP-PVPLPGQQQPVPSYP 171
PP PGA P+PG +PPP P A P PP+ G P P PLPG P P P
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPP--P 979
Query: 172 GYPGSGTVTPAVPP 185
PG+G P PP
Sbjct: 980 PLPGAG--IPPPPP 991
Score = 35.8 bits (81), Expect = 0.094
Identities = 38/150 (25%), Positives = 54/150 (36%), Gaps = 27/150 (18%)
Query: 81 GYPPVPPGGFGQPPSA-----QQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPP 135
G PP PPG P + V P + + P++ S PP P + +
Sbjct: 765 GRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQ 824
Query: 136 PGQQPPGAYPGQPPVTY--------------PGQPPVPLPGQQQPVPSYPGYPGSGTVTP 181
PG QPP + + ++ P PP+P S PG G V P
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC------TESSSSMPGLGMVPP 878
Query: 182 AVPPTQFGSRGTI--TDAPGFDPLRDAEVL 209
PP + T+ T P PL+ E+L
Sbjct: 879 PPPPLPGMTVPTLPSTAIPQPPPLQGTEML 908
Score = 34.3 bits (77), Expect = 0.27
Identities = 31/107 (28%), Positives = 38/107 (35%), Gaps = 31/107 (28%)
Query: 5 GYPPPPG----GYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAAN 60
G PPPP G PPA P G PPPP +P G
Sbjct: 1205 GIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSG--------------------PP 1244
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFG-----QPPSAQQPVPP 102
+ G + +P P G PP+P G FG S +QP+ P
Sbjct: 1245 LLPQVGSSTLPT--PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEP 1289
Score = 29.3 bits (64), Expect = 8.8
Identities = 34/124 (27%), Positives = 45/124 (36%), Gaps = 30/124 (24%)
Query: 32 PSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPG-----AGYPPVP 86
P+ PP V+ G F G+ + G GGA PG+P + +P
Sbjct: 232 PAAPPTA---VSPQPGAF-----LGLDRFLLGPSGGAGEA---PGSPDTEQALSALSDLP 280
Query: 87 PGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYP-------PYPGAPVPGQPMPPPGQQ 139
+P QQP P PGG P S PS P P + P PG++
Sbjct: 281 ESLAAEPREPQQP-------PSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEE 333
Query: 140 PPGA 143
GA
Sbjct: 334 AAGA 337
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 87.4 bits (215), Expect = 3e-17
Identities = 69/221 (31%), Positives = 92/221 (41%), Gaps = 28/221 (12%)
Query: 6 YPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF 65
YPPPP ++P + PPPP+ +DN SG+A +
Sbjct: 246 YPPPPQSDSASSPSPS-FSEDNLPPPPAEFSYPVDNQRG----------SGLAGPKRSSV 294
Query: 66 GGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPY-GMYPPP--------GGNPPSR 116
+ P P AP G PP P GF PP+ P PP G+ PPP G PP
Sbjct: 295 VSPSHP---PPAPPLGSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPS 351
Query: 117 MPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYP-GQPPVPLPGQQQPVPSYPGYPG 175
PS+PP+P P P PPP P P PP++ P G P P P P P P + G
Sbjct: 352 PPSFPPHPDFAAPPPPPPPPAADYPTLPP--PPLSQPTGGAPPPPPPPPPPGPPPPPFTG 409
Query: 176 SGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGF 216
+ PA+PP + + P R +++L +GF
Sbjct: 410 ADG-QPAIPPPLSDTTKPKSSLPAVSDAR-SDLLSAIRQGF 448
Score = 67.8 bits (164), Expect = 2e-11
Identities = 57/181 (31%), Positives = 64/181 (35%), Gaps = 58/181 (32%)
Query: 2 SYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANM 61
S+P PP G P PG P PPPP P IG+
Sbjct: 298 SHPPPAPPLGSPPGPKPGFAP---PPAPPPPPPPMIGIP--------------------- 333
Query: 62 SGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPP-------YGMYPPPGGNPP 114
PP PP GFG P + P PP + PPP P
Sbjct: 334 ---------------------PPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPA 372
Query: 115 SRMPSYPPYP-GAPVPGQPMPPPGQQPPGAYPGQPPVT-YPGQP--PVPLPGQQQPVPSY 170
+ P+ PP P P G P PPP PPG P PP T GQP P PL +P S
Sbjct: 373 ADYPTLPPPPLSQPTGGAPPPPPPPPPPG--PPPPPFTGADGQPAIPPPLSDTTKPKSSL 430
Query: 171 P 171
P
Sbjct: 431 P 431
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 82.4 bits (202), Expect = 9e-16
Identities = 74/196 (37%), Positives = 86/196 (43%), Gaps = 30/196 (15%)
Query: 4 PGYPPPPGGYPPAA--PGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANM 61
PG PPP G +PP PG P G PPP MPP + AG + G +
Sbjct: 235 PGMPPP-GSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPSAGTPGAGH-PGHGHSH 292
Query: 62 SGTFGGANMPN--------LYPGAPGAGYPPV-PPGGFGQPPSAQQPVPPYGMYPPPGGN 112
F MP+ + G G G+P PPG GQPP P PP GM P G
Sbjct: 293 PHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSGGQPP----PRPPPGM--PHPGP 346
Query: 113 PPSRMPSYPPYPGAPV--PGQPMPPPGQQPPGAYPGQPPVTYPGQP-PVPLPGQQQPVPS 169
PP MP P G+P+ PG PMPP G + P P PP Y G P P P Q+ P+P
Sbjct: 347 PPMGMPPRGPPFGSPMGHPG-PMPPHGMRGPP--PLMPPHGYTGPPRPPPYGYQRGPLP- 402
Query: 170 YPGYPGSGTVTPAVPP 185
P T P VPP
Sbjct: 403 ----PPRPTPRPPVPP 414
Score = 69.7 bits (169), Expect = 6e-12
Identities = 60/175 (34%), Positives = 70/175 (40%), Gaps = 23/175 (13%)
Query: 4 PGYPP--PPGGYPPAAPGGGPWG----GAAYPP-----PPSMPPIGLDNVATYAGQFNQD 52
PG PP PP PP A G GP GA +P P PP G+ + Q
Sbjct: 255 PGIPPAMPPPPMPPGAAGHGPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHH 314
Query: 53 YLSGMAANMSGT--FGGANMPNLYPGAPGAGYPPV--PPGG--FGQPPSAQQPVPPYGMY 106
G+ +G GG P PG P G PP+ PP G FG P P+PP+GM
Sbjct: 315 GPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMR 374
Query: 107 PPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLP 161
PP PP P P P+PPP P +PPV G PLP
Sbjct: 375 GPPPLMPPHGYTGPPRPPPYGYQRGPLPPPRPTP------RPPVPPRGPLRGPLP 423
Score = 53.1 bits (126), Expect = 6e-07
Identities = 37/93 (39%), Positives = 40/93 (43%), Gaps = 33/93 (35%)
Query: 93 PPSAQQPV--------PPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAY 144
PPSA PV PP GM PPPG PP P+PPPG PPG
Sbjct: 217 PPSAPNPVVSSLGSGLPPPGM-PPPGSFPP-----------------PVPPPGALPPGIP 258
Query: 145 PGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSG 177
P PP PP+P PG P G PG+G
Sbjct: 259 PAMPP------PPMP-PGAAGHGPPSAGTPGAG 284
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 79.7 bits (195), Expect = 6e-15
Identities = 65/188 (34%), Positives = 79/188 (42%), Gaps = 33/188 (17%)
Query: 4 PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63
P P P PP P P PPPPS G+ ++Y L M
Sbjct: 403 PPAHPAPVHQPPPLPHRPP------PPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGP 456
Query: 64 TFGG--------ANMP---NLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGN 112
++G A++P ++YP P PPVPP PP A P P YPPP
Sbjct: 457 SYGALPPAYGPPAHLPYHPHVYP--PNPPPPPVPPPPASFPPPAIPPPTP--GYPPP--- 509
Query: 113 PPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVP---S 169
PP+ P++PP P P +PP PPG G PP +YP PP PG Q PVP
Sbjct: 510 PPTYNPNFPPPPPRLPPTHAVPP--HPPPGL--GLPPASYP--PPAVPPGGQPPVPPPIP 563
Query: 170 YPGYPGSG 177
PG P G
Sbjct: 564 PPGMPPVG 571
Score = 59.3 bits (142), Expect = 8e-09
Identities = 60/204 (29%), Positives = 74/204 (36%), Gaps = 42/204 (20%)
Query: 7 PPPPG------GYPPAAPGGGPWGGAAYPPPPSMPPIGLD-NVATYAGQFNQDYLSGMAA 59
PPPP +PP P A+PPP PP+ A G + L +
Sbjct: 350 PPPPKIPKIETTHPPLPP--------AHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQI 401
Query: 60 NMSGTFGGANMPNLYPGAPGAGYPPVPPGGF------------GQPPSAQQPV-----PP 102
+ P P P PP PP + G+ + Q + P
Sbjct: 402 PPPAHPAPVHQPPPLPHRP----PPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPS 457
Query: 103 YGMYPPPGGNPPSRMPSYPP-YPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLP 161
YG PP G PP+ +P +P YP P P PPP PP A P PP PG PP P
Sbjct: 458 YGALPPAYG-PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIP--PPT--PGYPPPPPT 512
Query: 162 GQQQPVPSYPGYPGSGTVTPAVPP 185
P P P + V P PP
Sbjct: 513 YNPNFPPPPPRLPPTHAVPPHPPP 536
Score = 58.9 bits (141), Expect = 1e-08
Identities = 61/208 (29%), Positives = 78/208 (37%), Gaps = 50/208 (24%)
Query: 26 AAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS-----GTFGGANMPNLY---PGA 77
AA PPPP +P I + D +AA + G ++P + P
Sbjct: 347 AAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAH 406
Query: 78 PGAGY---------PPVPPGGF------------GQPPSAQQPV-----PPYGMYPPPGG 111
P + PP PP + G+ + Q + P YG PP G
Sbjct: 407 PAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYG 466
Query: 112 NPPSRMPSYP-PYPGAPVPGQPMPPPGQQPPGA-------YPGQPPVTYPGQPPVP--LP 161
PP+ +P +P YP P P PPP PP A YP PP P PP P LP
Sbjct: 467 -PPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLP 525
Query: 162 GQQQPVPSYP----GYPGSGTVTPAVPP 185
VP +P G P + PAVPP
Sbjct: 526 -PTHAVPPHPPPGLGLPPASYPPPAVPP 552
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/160 (30%), Positives = 55/160 (34%), Gaps = 71/160 (44%)
Query: 3 YPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS 62
YP PPP PP P + PPP++PP
Sbjct: 478 YPPNPPP----PPVPPPPASF------PPPAIPP-------------------------- 501
Query: 63 GTFGGANMPNLYPGAPGAGYPPVPP---GGFGQPPSAQQPVPPYGMYPPPG-GNPPSRMP 118
P GYPP PP F PP P +PPPG G PP+
Sbjct: 502 ---------------PTPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPA--- 543
Query: 119 SYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPV 158
SYPP P PPG QP P PP+ PG PPV
Sbjct: 544 SYPP---------PAVPPGGQP----PVPPPIPPPGMPPV 570
Score = 35.0 bits (79), Expect = 0.16
Identities = 17/37 (45%), Positives = 18/37 (48%), Gaps = 9/37 (24%)
Query: 2 SYPGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIG 38
SYP PPGG PP P PPP MPP+G
Sbjct: 544 SYPPPAVPPGGQPPVPPP---------IPPPGMPPVG 571
Score = 33.1 bits (74), Expect = 0.61
Identities = 19/42 (45%), Positives = 19/42 (45%), Gaps = 2/42 (4%)
Query: 4 PGYPPPPGGYPPAA--PGGGPWGGAAYPPPPSMPPIGLDNVA 43
PG PP YPP A PGG P PPP P GL A
Sbjct: 536 PGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRAA 577
Score = 29.3 bits (64), Expect = 8.8
Identities = 25/99 (25%), Positives = 32/99 (32%), Gaps = 16/99 (16%)
Query: 102 PYGMYPPPGGNPPSRMP-------SYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPG 154
P+ + PP P ++P S P P P P QQ P P + P P
Sbjct: 270 PHQLQQPPSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQP-KKPSPQPS 328
Query: 155 QP--------PVPLPGQQQPVPSYPGYPGSGTVTPAVPP 185
P P + P P P T P +PP
Sbjct: 329 SPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP 367
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 78.2 bits (191), Expect = 2e-14
Identities = 79/232 (34%), Positives = 88/232 (37%), Gaps = 44/232 (18%)
Query: 1 MSYPGYPPPPGG---------------YPPAAPGG----GPWGGAAYPPP------PSMP 35
MS G PPGG +P A PGG GP G PPP P P
Sbjct: 180 MSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP 239
Query: 36 PIGLDNVATYAGQFNQ-DYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPP 94
P+G G L A P L+PG P G PP+ P PP
Sbjct: 240 PLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP-FGQPPLGP----LPP 294
Query: 95 SAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPP-GQQPPGAYPGQPPVTYP 153
PVP YG PPPG PP + P PP P P P P+ PP PP PG P P
Sbjct: 295 GPPPPVPGYG--PPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPP----P 348
Query: 154 GQPPVPLPGQQQ---PVPSYPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDP 202
G PP P P P P+ G P S + P PPT R D + P
Sbjct: 349 GAPP-PAPHVNPAFFPPPTNSGMPTSDSRGP--PPTDPYGRPPPYDRGDYGP 397
Score = 67.0 bits (162), Expect = 4e-11
Identities = 61/192 (31%), Positives = 76/192 (39%), Gaps = 29/192 (15%)
Query: 32 PSMPPIGLDNVATYAGQFNQDYLSGMAAN--MSGTFGGANMPNLYPGAPGAG-YPPVPPG 88
P + P ++ + Q + SG + +G GG++ G G G +P PG
Sbjct: 154 PVVTPCNKQFLSQFEMQSRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGAVPG 213
Query: 89 G--FGQPPSAQQPVPPY--GMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPP--G 142
G F P P PP+ G PP PP P P PG P PGQ +PPP PP G
Sbjct: 214 GDRFPGPAGPGGPPPPFPAGQTPP---RPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG 270
Query: 143 AYPGQPPVTYPGQP-------------PVPLPG---QQQPVPSYPGYPGSGTVTPAVPPT 186
P PPV +PGQP P P+PG P P G P P PP
Sbjct: 271 DRP-PPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPG 329
Query: 187 QFGSRGTITDAP 198
G T+ P
Sbjct: 330 PLGPPLTLAPPP 341
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 73.9 bits (180), Expect = 3e-13
Identities = 67/207 (32%), Positives = 75/207 (36%), Gaps = 47/207 (22%)
Query: 4 PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63
P PP P PP PGG P P MPP G
Sbjct: 242 PPRPPLPESLPPPPPGGLPL--------PPMPPTG-----------------------PA 270
Query: 64 TFGGANMPNLYPGAPGAGYPPVP----PGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPS 119
G P L P APG +PP P P PP+ P G++PP G P
Sbjct: 271 PSGPPGPPQLPPPAPGV-HPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGV 329
Query: 120 YPPYPGA--PVPGQPMPPPGQQPPGAYPG-QPPVTYPGQPPVPLPGQQQPVPSYPG-YPG 175
+PP PG P PG P PG PP PG PP PG P P G P PG +P
Sbjct: 330 HPPAPGVHPPAPGVHPPAPGVHPPA--PGVHPPA--PGVHPPPSAGVH---PQAPGVHPA 382
Query: 176 SGTVTPAVPPTQFGSRGTITDAPGFDP 202
+ V P P + G APG P
Sbjct: 383 APAVHPQAPGVHPPAPGMHPQAPGVHP 409
Score = 73.6 bits (179), Expect = 4e-13
Identities = 63/198 (31%), Positives = 79/198 (39%), Gaps = 41/198 (20%)
Query: 4 PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63
P PP G P APG P +PP P + P SG+ G
Sbjct: 292 PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPP----------------TSGVHPPAPG 335
Query: 64 TFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPY 123
A P ++P APG +PP P G P P P G++P G P+ +P
Sbjct: 336 VHPPA--PGVHPPAPGV-HPPAP--GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQA 390
Query: 124 PGA--PVPGQPMPPPG--QQPPGAYPG------QPPVTYPG----QPPVPLPGQ-QQPVP 168
PG P PG PG QPPG +P QPP +P PP P+P + P+P
Sbjct: 391 PGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLP 450
Query: 169 SYPGYPGSGTVTPAVPPT 186
S G G + P PPT
Sbjct: 451 S----EGPGNIPPP-PPT 463
Score = 72.0 bits (175), Expect = 1e-12
Identities = 69/206 (33%), Positives = 81/206 (39%), Gaps = 31/206 (15%)
Query: 7 PPPPGGYP--PAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGT 64
PPPPGG P P P G G PP P G+ A + SG
Sbjct: 253 PPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV-----------VHPPASGV 301
Query: 65 FGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYP 124
A P ++P APG +PP P G P S P P G++PP G P +PP P
Sbjct: 302 HPPA--PGVHPPAPGV-HPPAP--GVHPPTSGVHPPAP-GVHPPAPGVHPPAPGVHPPAP 355
Query: 125 GA--PVPGQPMPPPG---QQPPGAYPGQPPVTYPGQPPV--PLPGQQQPVPS-YPGYPGS 176
G P PG PP Q PG +P P V +P P V P PG P +P PG
Sbjct: 356 GVHPPAPGVHPPPSAGVHPQAPGVHPAAPAV-HPQAPGVHPPAPGMHPQAPGVHPQPPG- 413
Query: 177 GTVTPAVPPTQFGSRGTITDAPGFDP 202
V P+ P G PG P
Sbjct: 414 --VHPSAPGVHPQPPGVHPSNPGVHP 437
Score = 62.4 bits (150), Expect = 9e-10
Identities = 68/217 (31%), Positives = 75/217 (34%), Gaps = 67/217 (30%)
Query: 9 PPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGA 68
PP PP+ P G P G PPPP M +G+
Sbjct: 217 PPA--PPSLPAGPP--GVKRPPPPLM--------------------NGLPPR-------- 244
Query: 69 NMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYP--PPGGN--PPSRMPSYPPYP 124
P P + PP PPGG PP +PP G P PPG PP +PP P
Sbjct: 245 ------PPLPES-LPPPPPGGLPLPP-----MPPTGPAPSGPPGPPQLPPPAPGVHPPAP 292
Query: 125 GA---------PVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPV-----PLPGQQQPVPS- 169
P PG P PG PP PG P T PP P PG P P
Sbjct: 293 VVHPPASGVHPPAPGVHPPAPGVHPPA--PGVHPPTSGVHPPAPGVHPPAPGVHPPAPGV 350
Query: 170 YPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDA 206
+P PG P V P S G APG P A
Sbjct: 351 HPPAPGVHPPAPGVHPPP--SAGVHPQAPGVHPAAPA 385
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 73.2 bits (178), Expect = 5e-13
Identities = 64/214 (29%), Positives = 74/214 (34%), Gaps = 20/214 (9%)
Query: 7 PPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66
P P GG +P G P AA PP P +AT + + + + G G
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSPKG--G 1254
Query: 67 GANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGA 126
A P P A PP GG PP P P P P G P + P P P A
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPA 1314
Query: 127 PVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVP-LPGQQQPVPSYPGYPGS--GTVTPAV 183
P P PG PP P P VT P P LP P P S G PA
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 184 PPTQFG---------SRGTITDAPGFDPLRDAEV 208
P+ G RG +P DP A +
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408
Score = 67.4 bits (163), Expect = 3e-11
Identities = 65/204 (31%), Positives = 70/204 (34%), Gaps = 38/204 (18%)
Query: 8 PPPGGYP--PAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTF 65
PPP G P PAA P GG A PPP P + AA
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAP-------------------TTPAATPPSPK 1183
Query: 66 GGANMPNLYPGAPG--AGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPY 123
GG P+ GAP A PP P GG P P P P P G + P P
Sbjct: 1184 GGLATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 124 PGAPVPGQPMPPPGQQPPGAYPGQPPVTYP----GQPPVPLPGQQQPV----PSYPGYP- 174
A P P P PP P P T P G P G P PS G P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 175 -----GSGTVTPAVPPTQFGSRGT 193
G+ T A PP+ GS GT
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGT 1326
Score = 65.5 bits (158), Expect = 1e-10
Identities = 62/196 (31%), Positives = 71/196 (36%), Gaps = 17/196 (8%)
Query: 2 SYPGYPPPPGGYPPAAPGG--GPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAA 59
S G P PP PP+ GG P A PP + PP +AT ++ + AA
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPP---HKGAPTTPAA 1131
Query: 60 NMSGTFGGANMPNLYPGAP--GAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRM 117
GG P GAP A PP P GG PP P P P P G +
Sbjct: 1132 TPPSPKGGLATPP-PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPS 1190
Query: 118 PSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSG 177
P P A P P P G P P P T PP P G P P G+
Sbjct: 1191 PKGAPTTPAATP--PSPKGGLATPS--PKGAPTTPAATPPSPKGGLATPSPK-----GAP 1241
Query: 178 TVTPAVPPTQFGSRGT 193
T A PP+ G T
Sbjct: 1242 TTPAATPPSPKGGPAT 1257
Score = 64.3 bits (155), Expect = 2e-10
Identities = 71/248 (28%), Positives = 85/248 (34%), Gaps = 55/248 (22%)
Query: 5 GYPPPPGGYPPA---APGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANM 61
G P PP PP+ +P P+ A PP + PP + A A + + AA +
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA--ATPLPKGAPTTPAATL 1064
Query: 62 SGTFGGANMPNLY-----PGA-------------------PGAGYPPVPPGGFGQPPSAQ 97
GG P+L P A P A PP P GG PP
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124
Query: 98 QPVPPYGMYPPPGGN----PPSRMPSYP-PYPGAPVPGQPMPPPGQQP--PGAYPGQP-- 148
P P P P G PP P+ P P +P G PPP P P A P P
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1184
Query: 149 ----------PVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRGTITDAP 198
P T PP P G P P G+ T A PP+ G G T +P
Sbjct: 1185 GLATPSPKGAPTTPAATPPSPKGGLATPSPK-----GAPTTPAATPPSPKG--GLATPSP 1237
Query: 199 GFDPLRDA 206
P A
Sbjct: 1238 KGAPTTPA 1245
Score = 63.5 bits (153), Expect = 4e-10
Identities = 62/203 (30%), Positives = 71/203 (34%), Gaps = 33/203 (16%)
Query: 4 PGYPPPPGG-YPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMS 62
P PPP G PPAA GG A PP P + + G
Sbjct: 1255 PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG--------------- 1299
Query: 63 GTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNP--PSRMPSY 120
G A P P A PP P G G PP P PP P P G P P+ PS
Sbjct: 1300 ---GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS 1356
Query: 121 PPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVT 180
P P + PP P ++ G P +T PP P G +PS G P S V
Sbjct: 1357 KGGPTTPSSKEGPTPPAATP--SHKGGPAMT----PPSPKRG--PAIPSPKGDPTSPAVI 1408
Query: 181 P----AVPPTQFGSRGTITDAPG 199
P P T G T + G
Sbjct: 1409 PLSPKKAPATPVTREGAATPSKG 1431
Score = 62.0 bits (149), Expect = 1e-09
Identities = 63/229 (27%), Positives = 73/229 (31%), Gaps = 52/229 (22%)
Query: 8 PPPGGYPPA-APGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFG 66
P P G P + +P G P AA PP P G
Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPK--------------------------------G 952
Query: 67 GANMPN-LYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPG 125
G P+ + P A PP P GG P P PP P P G P + P P P
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPP 1012
Query: 126 APVP--------GQPMPPPGQQPPGAYPGQP---PVTYP---GQPPVPLPGQQQPV--PS 169
A P P P PP A P P P P G P P P P+
Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPA 1072
Query: 170 YPGYPGSGTVTPAVPPTQFGSRGTITDAPGFDPLRDAEVLRKAMKGFGT 218
P G+ T A PP+ G G T +P P+ A G T
Sbjct: 1073 TPSLKGAPTPPAATPPSPKG--GPATPSPKGAPMPPAATPPSPKGGLAT 1119
Score = 59.7 bits (143), Expect = 6e-09
Identities = 60/206 (29%), Positives = 67/206 (32%), Gaps = 30/206 (14%)
Query: 7 PPPPGGYPPAAPGGGPWGGAAYPPPPS-----------------MPPIGLDNVATYAGQF 49
P P GG +P G P AA PP P PP + A A F
Sbjct: 971 PSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA--ATPF 1028
Query: 50 NQDYLSGMAANMSGTFGGANMPNLYPGAP--GAGYPPVPPGGFGQPPSAQQPVPPYGMYP 107
+ + AA G L GAP A P P GG P P PP P
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 108 PPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPV 167
P G P + P P P A P P P P P T PP P G P
Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT----PPSPKGGLATPP 1144
Query: 168 PSYPGYPGSGTVTPAVPPTQFGSRGT 193
P G+ T A PP+ G T
Sbjct: 1145 PK-----GAPTTPAATPPSPKGGLAT 1165
Score = 57.0 bits (136), Expect = 4e-08
Identities = 65/231 (28%), Positives = 77/231 (33%), Gaps = 60/231 (25%)
Query: 4 PGYPPPPGG-YPPAAPGGGPWGGAAYP-------PPPSMPPIGLDNVATYAGQFNQDYLS 55
P P P G PPAA P GG A P PP + PP AT + +
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK------- 983
Query: 56 GMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP---------PYGMY 106
G P P +P G P G PP+ P P P G
Sbjct: 984 ----------GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 107 PPPGGNPPSRM--PSYPPYP-GAPV-PGQPMP----------------PPGQQPPGAYPG 146
PP PPS P+ P P GAP P +P PP PP G
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP-KG 1092
Query: 147 QPPVTYPGQPPVPLPGQQQPVP----SYPGYPGSGTVTPAVPPTQFGSRGT 193
P P P+P P P P + P + G+ T A PP+ G T
Sbjct: 1093 GPATPSPKGAPMP-PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Score = 53.9 bits (128), Expect = 3e-07
Identities = 49/173 (28%), Positives = 59/173 (34%), Gaps = 14/173 (8%)
Query: 15 PAAPGGGPWGGAAYPPPP---SMPPIGLDNVATYAGQFNQDYLSGMAANMSGTFGGANMP 71
P +P G P A P P ++PP + F ++ G A +M
Sbjct: 858 PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE---GPATPAPKQAPALSMT 914
Query: 72 NLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQ 131
+ P A P P G P P PP P P G P + P + P P A P
Sbjct: 915 SSSPKKARA--TPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972
Query: 132 PMPPPGQQPPGAYPGQPPVTYPGQPPVPLPGQQQPVPSYPGYPGSGTVTPAVP 184
P P P P P T PP P G P P G P VTP P
Sbjct: 973 PKGGPATPSPKGAPTPPAAT----PPSPKGGPATPSPK--GAPTPPAVTPPSP 1019
Score = 50.4 bits (119), Expect = 4e-06
Identities = 70/260 (26%), Positives = 80/260 (30%), Gaps = 69/260 (26%)
Query: 8 PPPGGYP--PAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSG-----MAAN 60
P P G P PAA P GG A PPP P + G G +
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 61 MSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNP------- 113
S G A P P A PP P G G PP P PP P P G P
Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 114 -----------------PSRMPSY-------PPYP--GAPVP---GQPMPP--------- 135
P+ PS+ PP P G +P G P P
Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414
Query: 136 ----PGQQPPGAYPGQPPVTYPGQPPVPL---PGQQQP-----VPSYPGYPGSGTVTPAV 183
P + A P + +T P PV L P P PS G P VTP
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474
Query: 184 P-----PTQFGSRGTITDAP 198
P P Q + + AP
Sbjct: 1475 PKEPPAPKQVATSSSPKKAP 1494
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/154 (27%), Positives = 53/154 (34%), Gaps = 37/154 (24%)
Query: 77 APGAGYPPVPPGGFGQP-PSAQQPVPPYGMYPPPGGNP---------PSRMPSYPPYPGA 126
+P + P PP G P PSA P+ P G+ PP P P P+ P A
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 127 P--------------------VPGQPMPPPGQQPPGAYPGQP---PVT----YPGQPPVP 159
P +P P P PP A P P P T + PP
Sbjct: 909 PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 160 LPGQQQPVPSYPGYPGSGTVTPAVPPTQFGSRGT 193
P + P+ P G+ T A PP+ G T
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002
Score = 42.7 bits (99), Expect = 8e-04
Identities = 56/207 (27%), Positives = 69/207 (33%), Gaps = 24/207 (11%)
Query: 4 PGYPPPPGGYPPAAPGGGPWGGAAYPPPPSMPPIGLDNVATYAGQFNQDYLSGMAANMSG 63
P P GG + G P A PP P PP VAT + A
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP-KQVATSSSPKK-------APATPA 1498
Query: 64 TFGGANMPNLYPGAPGAGYPPVPPGGFGQP--PSAQ--QPVPPYGMYPPPGGNPPSR-MP 118
G +P + P +P P P P P+A P + P PP+ +P
Sbjct: 1499 PMGAPTLPAVIPSSPKE--VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVP 1556
Query: 119 SYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYPGQP-PVPL---PGQQQPVPSYPGYP 174
S P P P + P + + P P TY G P P L P P P P
Sbjct: 1557 SPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA--P 1614
Query: 175 GSGTVTPAVP---PTQFGSRGTITDAP 198
VTP P P +GT T P
Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPP 1641
Score = 36.6 bits (83), Expect = 0.055
Identities = 51/213 (23%), Positives = 67/213 (31%), Gaps = 46/213 (21%)
Query: 5 GYPPPPGGYPPA---APGGGPWGGAAYPP---PPS---MPPIGLDNVATYAGQFNQDYLS 55
G P PP PP+ +PG P GA PP PPS P + ++ G
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Query: 56 GMA--ANMSGTFGGANM----PNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP-------- 101
G A GG M P P P P P P P
Sbjct: 1368 GPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 102 ------------PYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPP-------G 142
P + P + P P+ P G P PP ++PP
Sbjct: 1428 PSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATS 1487
Query: 143 AYPGQPPVTYP--GQPPVP--LPGQQQPVPSYP 171
+ P + P T G P +P +P + VP+ P
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Score = 34.3 bits (77), Expect = 0.27
Identities = 26/82 (31%), Positives = 29/82 (35%), Gaps = 6/82 (7%)
Query: 71 PNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP-PYGMYPPPGGNPPSRMPSYPPYPGAPVP 129
P P P + PP PS + P P + PP PS P P P A P
Sbjct: 1567 PKEAPATPSSKEASSPPA---VTPSTYKGAPSPKELLIPPAVTSPS--PKEAPTPPAVTP 1621
Query: 130 GQPMPPPGQQPPGAYPGQPPVT 151
P P P P PPVT
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVT 1643
Score = 33.9 bits (76), Expect = 0.36
Identities = 31/109 (28%), Positives = 38/109 (34%), Gaps = 8/109 (7%)
Query: 75 PGAPGAGYPPVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMP 134
P + P PP PS +PP + P PS P P P+
Sbjct: 1785 PESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI 1844
Query: 135 PPGQQPPGAYPGQPPVTYPGQP-----PVPLPGQQQPVPSYPGYPGSGT 178
PP + G P Q + P PVP P +QPV GSGT
Sbjct: 1845 PP-EPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTK--NNKGSGT 1890
Score = 31.6 bits (70), Expect = 1.8
Identities = 27/75 (36%), Positives = 32/75 (42%), Gaps = 9/75 (12%)
Query: 118 PSYPPYPGAPVP------GQPMPPPGQQPPGAYPGQPPVTYPGQP-PVP-LPGQQQPVPS 169
P PP A P + +P P A P PPV+ P P PVP LP +QQ +PS
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS-PPVSLPLAPSPVPTLPPKQQFLPS 1819
Query: 170 YPGYPGSGTVTPAVP 184
PG P P
Sbjct: 1820 SPGLVLESPSKPLAP 1834
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,098,453
Number of Sequences: 37866
Number of extensions: 2194920
Number of successful extensions: 43097
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 697
Number of HSP's successfully gapped in prelim test: 1483
Number of HSP's that attempted gapping in prelim test: 11344
Number of HSP's gapped (non-prelim): 12261
length of query: 505
length of database: 18,247,518
effective HSP length: 107
effective length of query: 398
effective length of database: 14,195,856
effective search space: 5649950688
effective search space used: 5649950688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.