Search of human proteins with 221554539

Search of human proteins with 221554539

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221554539 docking protein 3 isoform 2 [Homo sapiens]
         (330 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|221554539 docking protein 3 isoform 2 [Homo sapiens]               678   0.0  
gi|221554537 docking protein 3 isoform 1 [Homo sapiens]               446   e-125
gi|221554541 docking protein 3 isoform 3 [Homo sapiens]               419   e-117
gi|4503357 docking protein 1 [Homo sapiens]                           143   2e-34
gi|41406050 docking protein 2 [Homo sapiens]                          139   5e-33
gi|40806175 diacylglycerol kinase, theta [Homo sapiens]                33   0.46 
gi|126091130 Gab3 protein isoform 1 [Homo sapiens]                     32   0.78 
gi|18079323 Gab3 protein isoform 2 [Homo sapiens]                      32   1.0  
gi|13027630 DiGeorge syndrome critical region protein 14 [Homo s...    31   1.7  
gi|116642878 hypothetical protein LOC400223 [Homo sapiens]             31   1.7  
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]          29   6.6  
gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo sapiens]     28   8.6  

>gi|221554539 docking protein 3 isoform 2 [Homo sapiens]
          Length = 330

 Score =  678 bits (1749), Expect = 0.0
 Identities = 330/330 (100%), Positives = 330/330 (100%)

Query: 1   MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS 60
           MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
Sbjct: 1   MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS 60

Query: 61  AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ 120
           AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
Sbjct: 61  AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ 120

Query: 121 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 180
           LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
Sbjct: 121 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 180

Query: 181 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII 240
           LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII
Sbjct: 181 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGII 240

Query: 241 LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQ 300
           LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQ
Sbjct: 241 LDESLLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQ 300

Query: 301 PRTQASCLQGSDCPAPHRNSTSAAHTLGTS 330
           PRTQASCLQGSDCPAPHRNSTSAAHTLGTS
Sbjct: 301 PRTQASCLQGSDCPAPHRNSTSAAHTLGTS 330


>gi|221554537 docking protein 3 isoform 1 [Homo sapiens]
          Length = 496

 Score =  446 bits (1146), Expect = e-125
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS 60
           MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS
Sbjct: 57  MDPLETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRS 116

Query: 61  AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ 120
           AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ
Sbjct: 117 AGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQ 176

Query: 121 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 180
           LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA
Sbjct: 177 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 236

Query: 181 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDK 215
           LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDK
Sbjct: 237 LLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDK 271


>gi|221554541 docking protein 3 isoform 3 [Homo sapiens]
          Length = 228

 Score =  419 bits (1078), Expect = e-117
 Identities = 206/206 (100%), Positives = 206/206 (100%)

Query: 125 GTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVL 184
           GTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVL
Sbjct: 23  GTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVL 82

Query: 185 GPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGIILDES 244
           GPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGIILDES
Sbjct: 83  GPDAIQLREAKGTQALYSWPYHFLRKFGSDKILLGTPGVSLLICKGERTDDVSGIILDES 142

Query: 245 LLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQPRTQ 304
           LLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQPRTQ
Sbjct: 143 LLRAYSVPGAGGHSRVQDSLGPVLREPTFQGERSFLKTSMLRSLLCSCSWRHPRSQPRTQ 202

Query: 305 ASCLQGSDCPAPHRNSTSAAHTLGTS 330
           ASCLQGSDCPAPHRNSTSAAHTLGTS
Sbjct: 203 ASCLQGSDCPAPHRNSTSAAHTLGTS 228



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 22/22 (100%), Positives = 22/22 (100%)

Query: 1  MDPLETPIKDGILYQQHVKFGK 22
          MDPLETPIKDGILYQQHVKFGK
Sbjct: 1  MDPLETPIKDGILYQQHVKFGK 22


>gi|4503357 docking protein 1 [Homo sapiens]
          Length = 481

 Score =  143 bits (361), Expect = 2e-34
 Identities = 90/221 (40%), Positives = 126/221 (57%), Gaps = 13/221 (5%)

Query: 4   LETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGP 63
           ++  + +G L+ Q  +FG K WRK WA+LY   P GVARLE ++ +    G++     G 
Sbjct: 1   MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHK----GSSSGGGRGS 56

Query: 64  GRRGERRVIRLADCVSVLPADGESCPR-DTGAFLLTTTERSHLLAAQ--HRQAWMGPICQ 120
            RR + +VIRLA+CVSV P   E+ P     AF L T +RSHLLAA      AW+  +C+
Sbjct: 57  SRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCR 116

Query: 121 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 180
            AFP  G  +   TD   PK   + M ENS+YS   E  +F V VQRTEAA RC L G  
Sbjct: 117 NAFP-KGSWTLAPTD-NPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSY 174

Query: 181 LLVLGPDAIQL----REAKGTQALYSWPYHFLRKFGSDKIL 217
           +L +  + + L     +++  + L SWPY  LR++G DK++
Sbjct: 175 VLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVM 215


>gi|41406050 docking protein 2 [Homo sapiens]
          Length = 412

 Score =  139 bits (349), Expect = 5e-33
 Identities = 100/222 (45%), Positives = 119/222 (53%), Gaps = 33/222 (14%)

Query: 8   IKDGILY-QQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGR- 65
           +K G LY QQ   FGKK WR+  A LY G    +ARLE  E              GP + 
Sbjct: 6   VKQGFLYLQQQQTFGKK-WRRFGASLYGGSDCALARLELQE--------------GPEKP 50

Query: 66  ---RGERRVIRLADCVSVLPADGE-SCPRDTGAFLLTTTERSHLLAAQ--HRQAWMGPIC 119
                 R+VIRL+DC+ V  A GE S PRDT AF L T ER +LLAA    R  W+  IC
Sbjct: 51  RRCEAARKVIRLSDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAIC 110

Query: 120 QLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVG---EFPVVVQRTEAATRCQL 176
            LAFPG  +  SG    QS       MEEN +YSS   VG   EF V ++ TEA+ RC L
Sbjct: 111 LLAFPGQRKELSGPEGKQSRPC----MEENELYSSAVTVGPHKEFAVTMRPTEASERCHL 166

Query: 177 KGPALLVLGPDAIQL--REAKGTQALYSWPYHFLRKFGSDKI 216
           +G   L  G  A++L      GTQ LY WPY FLR+FG DK+
Sbjct: 167 RGSYTLRAGESALELWGGPEPGTQ-LYDWPYRFLRRFGRDKV 207


>gi|40806175 diacylglycerol kinase, theta [Homo sapiens]
          Length = 942

 Score = 32.7 bits (73), Expect = 0.46
 Identities = 52/191 (27%), Positives = 72/191 (37%), Gaps = 47/191 (24%)

Query: 43  LESWEVRDGGLGAAGDRSAGPG-----------------------RRGERRVI---RLAD 76
           +E+ E  +GG GA G  + GPG                       RR + R++   RLA 
Sbjct: 265 VEAAEPGEGGDGADGSAAVGPGRETQATPESGKQTLKIFDGDDAVRRSQFRLVTVSRLAG 324

Query: 77  CVSVLPA--DGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQLAF-------PGTG 127
              VL A       P D G   L     S    +Q   AW G     A        PG+G
Sbjct: 325 AEEVLEAALRAHHIPEDPGHLELCRLPPS----SQACDAWAGGKAGSAVISEEGRSPGSG 380

Query: 128 EASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLG-- 185
           EA+  +   ++  R     E   IY  W +VG   V V+ T  +T   +    L +LG  
Sbjct: 381 EATPEAWVIRALPRA---QEVLKIYPGWLKVGVAYVSVRVTPKSTARSVVLEVLPLLGRQ 437

Query: 186 ---PDAIQLRE 193
              P++ QL E
Sbjct: 438 AESPESFQLVE 448


>gi|126091130 Gab3 protein isoform 1 [Homo sapiens]
          Length = 587

 Score = 32.0 bits (71), Expect = 0.78
 Identities = 43/182 (23%), Positives = 70/182 (38%), Gaps = 23/182 (12%)

Query: 19  KFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCV 78
           K  +  WRK W +L  G  SG   +  +             S+ P      RVI L++C 
Sbjct: 20  KLQRYAWRKRWFVLRRGRMSGNPDVLEY--------YRNKHSSKP-----IRVIDLSECA 66

Query: 79  ---SVLPADGESCPRDTGAFLLTTTERSHLLAA---QHRQAW---MGPICQLAFPGTGEA 129
               V P+      ++   F++ TT R+  L A   Q  Q W   +  +C L     G A
Sbjct: 67  VWKHVGPSFVRKEFQNNFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCNLGHLEDGAA 126

Query: 130 SSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAI 189
            S  + + +P   L P   +S+ ++       P     T A    + +  + L+  PD +
Sbjct: 127 DSMESLSYTPS-SLQPSSASSLLTAHAASSSLPRDDPNTNAVATEETRSESELLFLPDYL 185

Query: 190 QL 191
            L
Sbjct: 186 VL 187


>gi|18079323 Gab3 protein isoform 2 [Homo sapiens]
          Length = 586

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 43/180 (23%), Positives = 70/180 (38%), Gaps = 20/180 (11%)

Query: 19  KFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCV 78
           K  +  WRK W +L  G  SG   +  +             S+ P      RVI L++C 
Sbjct: 20  KLQRYAWRKRWFVLRRGRMSGNPDVLEY--------YRNKHSSKP-----IRVIDLSECA 66

Query: 79  ---SVLPADGESCPRDTGAFLLTTTERSHLLAA---QHRQAWMGPICQLAFPGTGEASSG 132
               V P+      ++   F++ TT R+  L A   Q  Q W+  I Q+   G  E  + 
Sbjct: 67  VWKHVGPSFVRKEFQNNFVFIVKTTSRTFYLVAKTEQEMQVWVHSISQVCNLGHLEDGAD 126

Query: 133 STDAQS-PKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQL 191
           S ++ S     L P   +S+ ++       P     T A    + +  + L+  PD + L
Sbjct: 127 SMESLSYTPSSLQPSSASSLLTAHAASSSLPRDDPNTNAVATEETRSESELLFLPDYLVL 186


>gi|13027630 DiGeorge syndrome critical region protein 14 [Homo
           sapiens]
          Length = 476

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 2/86 (2%)

Query: 101 ERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGE 160
           +++  L AQH+Q  +GP  +   P       G     +P     P    S   +W EV  
Sbjct: 266 QQAAALNAQHKQGKVGPDGKELIPQESPRVGGFGFVATPSPA--PGVNESPMMTWGEVEN 323

Query: 161 FPVVVQRTEAATRCQLKGPALLVLGP 186
            P+ V+ +E     +  GPA  +L P
Sbjct: 324 TPLRVEGSETPYVDRTPGPAFKILEP 349


>gi|116642878 hypothetical protein LOC400223 [Homo sapiens]
          Length = 166

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 17/91 (18%)

Query: 52  GLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHR 111
           G G+AG+ +A  G    R     A+C + L  DG +  R   AFL             HR
Sbjct: 69  GSGSAGEAAASLGTARVRS--GRAECTAKLAGDGHA--RLASAFL-------------HR 111

Query: 112 QAWMGPICQLAFPGTGEASSGSTDAQSPKRG 142
           +A + P      P  GE  S      SP+RG
Sbjct: 112 RAALPPPLGTCRPRLGEGGSAPALGPSPRRG 142


>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
          Length = 501

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 29/98 (29%), Positives = 38/98 (38%), Gaps = 11/98 (11%)

Query: 8   IKDGILYQQHVKFGKKCWRK------VWALLYAGGPSGVARLESWEVRDGGL-GAAGDRS 60
           IKDG+  Q    F +  W+K      +   L A   S  A  +S    D    GAAG  +
Sbjct: 296 IKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSSTAAAQSASATDTATPGAAGGAT 355

Query: 61  A----GPGRRGERRVIRLADCVSVLPADGESCPRDTGA 94
           A    G     E    R A   +V PAD  + P   G+
Sbjct: 356 AAAASGATSAPEGDAARAAKSDNVAPADRSATPATDGS 393


>gi|4504789 1D-myo-inositol-trisphosphate 3-kinase A [Homo
          sapiens]
          Length = 461

 Score = 28.5 bits (62), Expect = 8.6
 Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 5/60 (8%)

Query: 35 GGPSGVARLESWEVRDGGLGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPRDTGA 94
          GGP+G+AR         GL  A  RS      GE R++  A C +V  A     PR  GA
Sbjct: 5  GGPTGMARPGGARPCSPGLERAPRRSV-----GELRLLFEARCAAVAAAAAAGEPRARGA 59


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,016,153
Number of Sequences: 37866
Number of extensions: 723266
Number of successful extensions: 1742
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1725
Number of HSP's gapped (non-prelim): 14
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.