Guide to the Human Genome
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Search of human proteins with 22095331

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22095331 hypothetical protein LOC23065 [Homo sapiens]
         (993 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22095331 hypothetical protein LOC23065 [Homo sapiens]             1975   0.0  
gi|226498382 tetratricopeptide repeat domain 5 [Homo sapiens]          33   1.0  
gi|16306568 poly(A) polymerase gamma [Homo sapiens]                    32   3.0  
gi|169162091 PREDICTED: similar to Kinesin-Like Protein family m...    32   3.9  
gi|239741525 PREDICTED: hypothetical protein [Homo sapiens]            32   3.9  
gi|21735548 centrosomal protein 2 [Homo sapiens]                       31   6.6  

>gi|22095331 hypothetical protein LOC23065 [Homo sapiens]
          Length = 993

 Score = 1975 bits (5116), Expect = 0.0
 Identities = 993/993 (100%), Positives = 993/993 (100%)

Query: 1   MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK 60
           MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK
Sbjct: 1   MAAEWASRFWLWATLLIPAAAVYEDQVGKFDWRQQYVGKVKFASLEFSPGSKKLVVATEK 60

Query: 61  NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE 120
           NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE
Sbjct: 61  NVIAALNSRTGEILWRHVDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETNIGGLNWE 120

Query: 121 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS 180
           ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS
Sbjct: 121 ITLDSGSFQALGLVGLQESVRYIAVLKKTTLALHHLSSGHLKWVEHLPESDSIHYQMVYS 180

Query: 181 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP 240
           YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP
Sbjct: 181 YGSGVVWALGVVPFSHVNIVKFNVEDGEIVQQVRVSTPWLQHLSGACGVVDEAVLVCPDP 240

Query: 241 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY 300
           SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY
Sbjct: 241 SSRSLQTLALETEWELRQIPLQSLDLEFGSGFQPRVLPTQPNPVDASRAQFFLHLSPSHY 300

Query: 301 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS 360
           ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS
Sbjct: 301 ALLQYHYGTLSLLKNFPQTALVSFATTGEKTVAAVMACRNEVQKSSSSEDGSMGSFSEKS 360

Query: 361 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR 420
           SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR
Sbjct: 361 SSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLEQSGTRPERLYIQVFLKKDDSVGYR 420

Query: 421 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL 480
           ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL
Sbjct: 421 ALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEFGKKADGL 480

Query: 481 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT 540
           LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT
Sbjct: 481 LGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQKMMVMVT 540

Query: 541 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS 600
           ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS
Sbjct: 541 ASGKLFGIESSSGTILWKQYLPNVKPDSSFKLMVQRTTAHFPHPPQCTLLVKDKESGMSS 600

Query: 601 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR 660
           LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR
Sbjct: 601 LYVFNPIFGKWSQVAPPVLKRPILQSLLLPVMDQDYAKVLLLIDDEYKVTAFPATRNVLR 660

Query: 661 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH 720
           QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH
Sbjct: 661 QLHELAPSIFFYLVDAEQGRLCGYRLRKDLTTELSWELTIPPEVQRIVKVKGKRSSEHVH 720

Query: 721 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG 780
           SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG
Sbjct: 721 SQGRVMGDRSVLYKSLNPNLLAVVTESTDAHHERTFIGIFLIDGVTGRIIHSSVQKKAKG 780

Query: 781 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF 840
           PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF
Sbjct: 781 PVHIVHSENWVVYQYWNTKARRNEFTVLELYEGTEQYNATAFSSLDRPQLPQVLQQSYIF 840

Query: 841 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP 900
           PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP
Sbjct: 841 PSSISAMEATITERGITSRHLLIGLPSGAILSLPKALLDPRRPEIPTEQSREENLIPYSP 900

Query: 901 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY 960
           DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY
Sbjct: 901 DVQIHAERFINYNQTVSRMRGIYTAPSGLESTCLVVAYGLDIYQTRVYPSKQFDVLKDDY 960

Query: 961 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR 993
           DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR
Sbjct: 961 DYVLISSVLFGLVFATMITKRLAQVKLLNRAWR 993


>gi|226498382 tetratricopeptide repeat domain 5 [Homo sapiens]
          Length = 440

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 23/96 (23%), Positives = 46/96 (47%), Gaps = 7/96 (7%)

Query: 24  EDQVGKFDWRQQYV---GKVKFASLEFSPGSKKLV---VATEKNVIAALNSRTGEILWRH 77
           E+ VG    + Q +   GK    + ++SP +++L+   V  E  ++ A N + GE+ W+ 
Sbjct: 58  EEVVGSVQGKAQVLMLTGKALNVTPDYSPKAEELLSKAVKLEPELVEAWN-QLGEVYWKK 116

Query: 78  VDKGTAEGAVDAMLLHGQDVITVSNGGRIMRSWETN 113
            D   A       L H ++ +++ N   ++R   T+
Sbjct: 117 GDVAAAHTCFSGALTHCRNKVSLQNLSMVLRQLRTD 152


>gi|16306568 poly(A) polymerase gamma [Homo sapiens]
          Length = 736

 Score = 32.0 bits (71), Expect = 3.0
 Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 11/65 (16%)

Query: 569 SFKLMVQRTTAHFPHPPQCTLLVKDKESGMSSLYVFNPIFGKWSQVAPPVLKRPILQSLL 628
           S+ ++V RT   +P+    TL+ K           F  +F KW    P +LK+P   +L 
Sbjct: 247 SWAMLVARTCQLYPNAAASTLVHK-----------FFLVFSKWEWPNPVLLKQPEESNLN 295

Query: 629 LPVMD 633
           LPV D
Sbjct: 296 LPVWD 300


>gi|169162091 PREDICTED: similar to Kinesin-Like Protein family
           member (klp-6) [Homo sapiens]
          Length = 609

 Score = 31.6 bits (70), Expect = 3.9
 Identities = 31/131 (23%), Positives = 64/131 (48%), Gaps = 15/131 (11%)

Query: 414 DDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEF 473
           +++V + AL  +++  L +L+  A  V LW  +E   E+ C ++  L +TG         
Sbjct: 303 EETVQFAALTASQE-FLNYLRTNALIVDLWGLQEGCTELSCSQL-GLMVTG--------- 351

Query: 474 GKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQ 533
               +G + +  K++S+   + QA ++ + +++    K   + +   NI+   R+E  L 
Sbjct: 352 ----EGHILVDTKKISTVKDISQAASNQIPELYLKLLKLEQETEPLRNINRALREENVLL 407

Query: 534 KMMVMVTASGK 544
           K  +  TASG+
Sbjct: 408 KASLAKTASGQ 418


>gi|239741525 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 372

 Score = 31.6 bits (70), Expect = 3.9
 Identities = 31/131 (23%), Positives = 64/131 (48%), Gaps = 15/131 (11%)

Query: 414 DDSVGYRALVQTEDHLLLFLQQLAGKVVLWSREESLAEVVCLEMVDLPLTGAQAELEGEF 473
           +++V + AL  +++  L +L+  A  V LW  +E   E+ C ++  L +TG         
Sbjct: 77  EETVQFAALTASQE-FLNYLRTNALIVDLWGLQEGCTELSCSQL-GLMVTG--------- 125

Query: 474 GKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKPRSQIKNEINIDTLARDEFNLQ 533
               +G + +  K++S+   + QA ++ + +++    K   + +   NI+   R+E  L 
Sbjct: 126 ----EGHILVDTKKISTVKDISQAASNQIPELYLKLLKLEQETEPLRNINRALREENVLL 181

Query: 534 KMMVMVTASGK 544
           K  +  TASG+
Sbjct: 182 KASLAKTASGQ 192


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 30.8 bits (68), Expect = 6.6
 Identities = 45/207 (21%), Positives = 88/207 (42%), Gaps = 20/207 (9%)

Query: 337 ACRNEVQKSSSSEDGSMGSFSEKSSSKDSLACFNQTYTINLYLVETGRRLLDTTITFSLE 396
           A R  +QK +   D   G   +     DSL+   +       L++  R  L   +   LE
Sbjct: 432 ALRQRLQKLTGERDTLAGQTVDLQGEVDSLSKERE-------LLQKAREELRQQLEV-LE 483

Query: 397 QSGTRPERLYIQVFLKKDDSVGYRALVQTEDHLLLFLQQLAGKVVLW---SREESLAEVV 453
           Q   R  R+ +++ L+ D + G +   Q E HL +  ++   ++++     + ESL+E++
Sbjct: 484 QEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERERLQEMLMGLEAKQSESLSELI 543

Query: 454 CL-EMVDLPLTGAQAELEGEFGKKADGLLGMFLKRLSSQLILLQAWTSHLWKMFYDARKP 512
            L E ++       + LEGE  ++    +   L R    +  L +  + L     D R  
Sbjct: 544 TLREALE------SSHLEGELLRQEQTEVTAALARAEQSIAELSSSENTLKTEVADLR-- 595

Query: 513 RSQIKNEINIDTLARDEFNLQKMMVMV 539
            + +K     + LA D+  L + ++ +
Sbjct: 596 AAAVKLSALNEALALDKVGLNQQLLQL 622


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,292,301
Number of Sequences: 37866
Number of extensions: 1569639
Number of successful extensions: 3739
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3737
Number of HSP's gapped (non-prelim): 7
length of query: 993
length of database: 18,247,518
effective HSP length: 112
effective length of query: 881
effective length of database: 14,006,526
effective search space: 12339749406
effective search space used: 12339749406
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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