Guide to the Human Genome
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Search of human proteins with 21614511

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21614511 fibroblast growth factor 12 isoform 2 [Homo
sapiens]
         (181 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]      370   e-103
gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]      363   e-101
gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]      286   7e-78
gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]     285   1e-77
gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]     268   2e-72
gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]     266   7e-72
gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]     266   7e-72
gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]     266   7e-72
gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]       264   3e-71
gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]      264   3e-71
gi|4758362 fibroblast growth factor 11 [Homo sapiens]                 221   2e-58
gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]        119   2e-27
gi|9789947 fibroblast growth factor 20 [Homo sapiens]                 115   3e-26
gi|4503691 fibroblast growth factor 16 [Homo sapiens]                 114   5e-26
gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]        97   1e-20
gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo...    94   6e-20
gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]         92   2e-19
gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]         92   2e-19
gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]        90   9e-19
gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]       88   4e-18
gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]         86   2e-17
gi|222144221 fibroblast growth factor 1 (acidic) isoform 1 propr...    80   1e-15
gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprot...    80   1e-15
gi|222144273 fibroblast growth factor 1 (acidic) isoform 1 propr...    80   1e-15
gi|222144271 fibroblast growth factor 1 (acidic) isoform 1 propr...    80   1e-15
gi|153285461 fibroblast growth factor 2 [Homo sapiens]                 71   4e-13
gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]        50   1e-06
gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]       49   2e-06
gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]        49   2e-06
gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]        48   4e-06

>gi|21614511 fibroblast growth factor 12 isoform 2 [Homo sapiens]
          Length = 181

 Score =  370 bits (950), Expect = e-103
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 60
           MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK
Sbjct: 1   MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 60

Query: 61  ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 120
           ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ
Sbjct: 61  ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 120

Query: 121 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS 180
           IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS
Sbjct: 121 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDS 180

Query: 181 T 181
           T
Sbjct: 181 T 181


>gi|11136630 fibroblast growth factor 12 isoform 1 [Homo sapiens]
          Length = 243

 Score =  363 bits (931), Expect = e-101
 Identities = 177/177 (100%), Positives = 177/177 (100%)

Query: 5   EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
           EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY
Sbjct: 67  EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 126

Query: 65  VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
           VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG
Sbjct: 127 VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 186

Query: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST 181
           NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST
Sbjct: 187 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST 243


>gi|4758368 fibroblast growth factor 14 isoform 1A [Homo sapiens]
          Length = 247

 Score =  286 bits (732), Expect = 7e-78
 Identities = 137/186 (73%), Positives = 161/186 (86%), Gaps = 5/186 (2%)

Query: 1   MESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVK 60
           +  ++PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQGVK
Sbjct: 61  LRRQDPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVK 120

Query: 61  ASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQ 120
             LY+AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKEGQ
Sbjct: 121 TGLYIAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQ 180

Query: 121 IMKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGGKV 175
            MKGNRVKKTKP++HF+PKP+EV MYREPSLH++GE   K G   S+ +S +  MNGGK 
Sbjct: 181 AMKGNRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKP 240

Query: 176 VNQDST 181
           VN+  T
Sbjct: 241 VNKSKT 246


>gi|28872756 fibroblast growth factor 14 isoform 1B [Homo sapiens]
          Length = 252

 Score =  285 bits (730), Expect = 1e-77
 Identities = 137/182 (75%), Positives = 159/182 (87%), Gaps = 5/182 (2%)

Query: 5   EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
           +PQLKGIVTRL+ +QGY+LQMHPDG +DGTKD++++ TLFNLIPVGLRVVAIQGVK  LY
Sbjct: 70  DPQLKGIVTRLYCRQGYYLQMHPDGALDGTKDDSTNSTLFNLIPVGLRVVAIQGVKTGLY 129

Query: 65  VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
           +AMNGEGYLY S++FTPECKFKESVFENYYVIYSS LYRQQESGRAWFLGLNKEGQ MKG
Sbjct: 130 IAMNGEGYLYPSELFTPECKFKESVFENYYVIYSSMLYRQQESGRAWFLGLNKEGQAMKG 189

Query: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE---KQG--RSRKSSGTPTMNGGKVVNQD 179
           NRVKKTKP++HF+PKP+EV MYREPSLH++GE   K G   S+ +S +  MNGGK VN+ 
Sbjct: 190 NRVKKTKPAAHFLPKPLEVAMYREPSLHDVGETVPKPGVTPSKSTSASAIMNGGKPVNKS 249

Query: 180 ST 181
            T
Sbjct: 250 KT 251


>gi|213417606 fibroblast growth factor 13 isoform 4 [Homo sapiens]
          Length = 199

 Score =  268 bits (684), Expect = 2e-72
 Identities = 129/187 (68%), Positives = 156/187 (83%), Gaps = 11/187 (5%)

Query: 3   SKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKAS 62
           SKEPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+  
Sbjct: 15  SKEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTK 74

Query: 63  LYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIM 122
           LY+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IM
Sbjct: 75  LYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIM 134

Query: 123 KGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGK 174
           KGN VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGGK
Sbjct: 135 KGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGK 191

Query: 175 VVNQDST 181
            ++ + +
Sbjct: 192 SMSHNES 198


>gi|213417634 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score =  266 bits (680), Expect = 7e-72
 Identities = 128/188 (68%), Positives = 156/188 (82%), Gaps = 11/188 (5%)

Query: 2   ESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKA 61
           E +EPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ 
Sbjct: 41  EPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQT 100

Query: 62  SLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQI 121
            LY+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+I
Sbjct: 101 KLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEI 160

Query: 122 MKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGG 173
           MKGN VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGG
Sbjct: 161 MKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGG 217

Query: 174 KVVNQDST 181
           K ++ + +
Sbjct: 218 KSMSHNES 225


>gi|213417614 fibroblast growth factor 13 isoform 3 [Homo sapiens]
          Length = 226

 Score =  266 bits (680), Expect = 7e-72
 Identities = 128/188 (68%), Positives = 156/188 (82%), Gaps = 11/188 (5%)

Query: 2   ESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKA 61
           E +EPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ 
Sbjct: 41  EPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQT 100

Query: 62  SLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQI 121
            LY+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+I
Sbjct: 101 KLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEI 160

Query: 122 MKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGG 173
           MKGN VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGG
Sbjct: 161 MKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGG 217

Query: 174 KVVNQDST 181
           K ++ + +
Sbjct: 218 KSMSHNES 225


>gi|213417610 fibroblast growth factor 13 isoform 2 [Homo sapiens]
          Length = 255

 Score =  266 bits (680), Expect = 7e-72
 Identities = 128/188 (68%), Positives = 156/188 (82%), Gaps = 11/188 (5%)

Query: 2   ESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKA 61
           E +EPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+ 
Sbjct: 70  EPEEPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQT 129

Query: 62  SLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQI 121
            LY+AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+I
Sbjct: 130 KLYLAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEI 189

Query: 122 MKGNRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGG 173
           MKGN VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGG
Sbjct: 190 MKGNHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGG 246

Query: 174 KVVNQDST 181
           K ++ + +
Sbjct: 247 KSMSHNES 254


>gi|4758366 fibroblast growth factor 13 isoform 1 [Homo sapiens]
          Length = 245

 Score =  264 bits (675), Expect = 3e-71
 Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)

Query: 5   EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
           EPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+  LY
Sbjct: 63  EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 122

Query: 65  VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
           +AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 123 LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 182

Query: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 176
           N VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGGK +
Sbjct: 183 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 239

Query: 177 NQDST 181
           + + +
Sbjct: 240 SHNES 244


>gi|16306543 fibroblast growth factor 13 isoform 5 [Homo sapiens]
          Length = 192

 Score =  264 bits (675), Expect = 3e-71
 Identities = 127/185 (68%), Positives = 154/185 (83%), Gaps = 11/185 (5%)

Query: 5   EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
           EPQLKGIVT+L+S+QGY LQ+  DGTIDGTKDE+S YTLFNLIPVGLRVVAIQGV+  LY
Sbjct: 10  EPQLKGIVTKLYSRQGYHLQLQADGTIDGTKDEDSTYTLFNLIPVGLRVVAIQGVQTKLY 69

Query: 65  VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
           +AMN EGYLY+S++FTPECKFKESVFENYYV YSS +YRQQ+SGR W+LGLNKEG+IMKG
Sbjct: 70  LAMNSEGYLYTSELFTPECKFKESVFENYYVTYSSMIYRQQQSGRGWYLGLNKEGEIMKG 129

Query: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGEKQGRSRKSSGTPT--------MNGGKVV 176
           N VKK KP++HF+PKP++V MY+EPSLH++ E    SR  SGTPT        +NGGK +
Sbjct: 130 NHVKKNKPAAHFLPKPLKVAMYKEPSLHDLTE---FSRSGSGTPTKSRSVSGVLNGGKSM 186

Query: 177 NQDST 181
           + + +
Sbjct: 187 SHNES 191


>gi|4758362 fibroblast growth factor 11 [Homo sapiens]
          Length = 225

 Score =  221 bits (564), Expect = 2e-58
 Identities = 103/152 (67%), Positives = 126/152 (82%)

Query: 5   EPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLY 64
           EPQLKGIVT+LF +QG++LQ +PDG+I GT ++ S +T FNLIPVGLRVV IQ  K   Y
Sbjct: 65  EPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHY 124

Query: 65  VAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG 124
           +AMN EG LYSS  FT EC+FKE VFENYYV+Y+S LYRQ+ SGRAW+LGL+KEGQ+MKG
Sbjct: 125 MAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKG 184

Query: 125 NRVKKTKPSSHFVPKPIEVCMYREPSLHEIGE 156
           NRVKKTK ++HF+PK +EV MY+EPSLH + E
Sbjct: 185 NRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPE 216


>gi|4503707 fibroblast growth factor 9 precursor [Homo sapiens]
          Length = 208

 Score =  119 bits (297), Expect = 2e-27
 Identities = 54/137 (39%), Positives = 92/137 (67%), Gaps = 2/137 (1%)

Query: 8   LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 65
           LKGI+ R  L+ + G+ L++ P+GTI GT+ ++S + +   I + + +V+I+GV + LY+
Sbjct: 57  LKGILRRRQLYCRTGFHLEIFPNGTIQGTRKDHSRFGILEFISIAVGLVSIRGVDSGLYL 116

Query: 66  AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 125
            MN +G LY S+  T EC F+E   EN+Y  YSS LY+  ++GR +++ LNK+G   +G 
Sbjct: 117 GMNEKGELYGSEKLTQECVFREQFEENWYNTYSSNLYKHVDTGRRYYVALNKDGTPREGT 176

Query: 126 RVKKTKPSSHFVPKPIE 142
           R K+ +  +HF+P+P++
Sbjct: 177 RTKRHQKFTHFLPRPVD 193


>gi|9789947 fibroblast growth factor 20 [Homo sapiens]
          Length = 211

 Score =  115 bits (287), Expect = 3e-26
 Identities = 54/137 (39%), Positives = 90/137 (65%), Gaps = 2/137 (1%)

Query: 8   LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 65
           L GI+ R  L+ + G+ LQ+ PDG++ GT+ ++S + +   I V + +V+I+GV + LY+
Sbjct: 60  LHGILRRRQLYCRTGFHLQILPDGSVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYL 119

Query: 66  AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 125
            MN +G LY S+  T EC F+E   EN+Y  YSS +Y+  ++GR +F+ LNK+G    G 
Sbjct: 120 GMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGA 179

Query: 126 RVKKTKPSSHFVPKPIE 142
           R K+ +  +HF+P+P++
Sbjct: 180 RSKRHQKFTHFLPRPVD 196


>gi|4503691 fibroblast growth factor 16 [Homo sapiens]
          Length = 207

 Score =  114 bits (285), Expect = 5e-26
 Identities = 52/137 (37%), Positives = 90/137 (65%), Gaps = 2/137 (1%)

Query: 8   LKGIVTR--LFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYV 65
           LKGI+ R  L+ + G+ L++ P+GT+ GT+ ++S + +   I + + +++I+GV + LY+
Sbjct: 56  LKGILRRRQLYCRTGFHLEIFPNGTVHGTRHDHSRFGILEFISLAVGLISIRGVDSGLYL 115

Query: 66  AMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGN 125
            MN  G LY S   T EC F+E   EN+Y  Y+STLY+  +S R +++ LNK+G   +G 
Sbjct: 116 GMNERGELYGSKKLTRECVFREQFEENWYNTYASTLYKHSDSERQYYVALNKDGSPREGY 175

Query: 126 RVKKTKPSSHFVPKPIE 142
           R K+ +  +HF+P+P++
Sbjct: 176 RTKRHQKFTHFLPRPVD 192


>gi|4758360 fibroblast growth factor 10 precursor [Homo sapiens]
          Length = 208

 Score = 96.7 bits (239), Expect = 1e-20
 Identities = 46/125 (36%), Positives = 76/125 (60%), Gaps = 2/125 (1%)

Query: 14  RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYL 73
           +LFS   YFL++  +G + GTK EN  Y++  +  V + VVA++ + ++ Y+AMN +G L
Sbjct: 81  KLFSFTKYFLKIEKNGKVSGTKKENCPYSILEITSVEIGVVAVKAINSNYYLAMNKKGKL 140

Query: 74  YSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPS 133
           Y S  F  +CK KE + EN Y  Y+S  +  Q +GR  ++ LN +G   +G + ++   S
Sbjct: 141 YGSKEFNNDCKLKERIEENGYNTYAS--FNWQHNGRQMYVALNGKGAPRRGQKTRRKNTS 198

Query: 134 SHFVP 138
           +HF+P
Sbjct: 199 AHFLP 203


>gi|73486655 fibroblast growth factor 5 isoform 1 precursor [Homo
           sapiens]
          Length = 268

 Score = 94.0 bits (232), Expect = 6e-20
 Identities = 45/122 (36%), Positives = 80/122 (65%), Gaps = 3/122 (2%)

Query: 20  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 79
           G+ LQ++PDG ++G+ + N   ++  +  V   +V I+GV ++ ++AM+ +G L++S  F
Sbjct: 98  GFHLQIYPDGKVNGSHEANM-LSVLEIFAVSQGIVGIRGVFSNKFLAMSKKGKLHASAKF 156

Query: 80  TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKG--NRVKKTKPSSHFV 137
           T +CKF+E   EN Y  Y+S ++R +++GR W++ LNK G+  +G   RVK    S+HF+
Sbjct: 157 TDDCKFRERFQENSYNTYASAIHRTEKTGREWYVALNKRGKAKRGCSPRVKPQHISTHFL 216

Query: 138 PK 139
           P+
Sbjct: 217 PR 218


>gi|4503705 fibroblast growth factor 7 precursor [Homo sapiens]
          Length = 194

 Score = 92.0 bits (227), Expect = 2e-19
 Identities = 44/130 (33%), Positives = 79/130 (60%), Gaps = 2/130 (1%)

Query: 12  VTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEG 71
           V RLF +  ++L++   G + GT++  ++Y +  +  V + +VAI+GV++  Y+AMN EG
Sbjct: 66  VRRLFCRTQWYLRIDKRGKVKGTQEMKNNYNIMEIRTVAVGIVAIKGVESEFYLAMNKEG 125

Query: 72  YLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTK 131
            LY+      +C FKE + EN+Y  Y+S   +   +G   F+ LN++G  ++G + KK +
Sbjct: 126 KLYAKKECNEDCNFKELILENHYNTYASA--KWTHNGGEMFVALNQKGIPVRGKKTKKEQ 183

Query: 132 PSSHFVPKPI 141
            ++HF+P  I
Sbjct: 184 KTAHFLPMAI 193


>gi|4885233 fibroblast growth factor 3 precursor [Homo sapiens]
          Length = 239

 Score = 92.0 bits (227), Expect = 2e-19
 Identities = 47/139 (33%), Positives = 84/139 (60%), Gaps = 11/139 (7%)

Query: 14  RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYL 73
           +L+    Y LQ+HP G ++G+  ENS Y++  +  V + +VAI+G+ +  Y+AMN  G L
Sbjct: 47  KLYCATKYHLQLHPSGRVNGSL-ENSAYSILEITAVEVGIVAIRGLFSGRYLAMNKRGRL 105

Query: 74  YSSDVFTPECKFKESVFENYYVIYSSTLY----------RQQESGRAWFLGLNKEGQIMK 123
           Y+S+ ++ EC+F E + E  Y  Y+S LY          RQ  + R W++ +N +G+  +
Sbjct: 106 YASEHYSAECEFVERIHELGYNTYASRLYRTVSSTPGARRQPSAERLWYVSVNGKGRPRR 165

Query: 124 GNRVKKTKPSSHFVPKPIE 142
           G + ++T+ SS F+P+ ++
Sbjct: 166 GFKTRRTQKSSLFLPRVLD 184


>gi|15147343 fibroblast growth factor 6 precursor [Homo sapiens]
          Length = 208

 Score = 90.1 bits (222), Expect = 9e-19
 Identities = 46/120 (38%), Positives = 75/120 (62%), Gaps = 7/120 (5%)

Query: 20  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 79
           G+ LQ+ PDG I GT +EN  Y+L  +  V   VV++ GV+++L+VAMN +G LY++  F
Sbjct: 95  GFHLQVLPDGRISGTHEENP-YSLLEISTVERGVVSLFGVRSALFVAMNSKGRLYATPSF 153

Query: 80  TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 139
             ECKF+E++  N Y  Y S LY      +  ++ L+K G++ +G++V      +HF+P+
Sbjct: 154 QEECKFRETLLPNNYNAYESDLY------QGTYIALSKYGRVKRGSKVSPIMTVTHFLPR 207


>gi|10190672 fibroblast growth factor 22 precursor [Homo sapiens]
          Length = 170

 Score = 88.2 bits (217), Expect = 4e-18
 Identities = 48/135 (35%), Positives = 79/135 (58%), Gaps = 4/135 (2%)

Query: 6   PQLKGIVT--RLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASL 63
           P L+G V   RLFS   +FL++ P G + GT+  +   ++  +  V + VV I+ V +  
Sbjct: 34  PHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGF 93

Query: 64  YVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMK 123
           YVAMN  G LY S ++T +C+F+E + EN +  Y+S  +R++  G+  FL L++ G    
Sbjct: 94  YVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRR--GQPMFLALDRRGGPRP 151

Query: 124 GNRVKKTKPSSHFVP 138
           G R ++   S+HF+P
Sbjct: 152 GGRTRRYHLSAHFLP 166


>gi|4503701 fibroblast growth factor 4 precursor [Homo sapiens]
          Length = 206

 Score = 85.5 bits (210), Expect = 2e-17
 Identities = 50/120 (41%), Positives = 65/120 (54%), Gaps = 7/120 (5%)

Query: 20  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 79
           G+ LQ  PDG I G   +  D +L  L PV   VV+I GV +  +VAM+ +G LY S  F
Sbjct: 93  GFHLQALPDGRIGGAHADTRD-SLLELSPVERGVVSIFGVASRFFVAMSSKGKLYGSPFF 151

Query: 80  TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPK 139
           T EC FKE +  N Y  Y S  Y         F+ L+K G+  KGNRV  T   +HF+P+
Sbjct: 152 TDECTFKEILLPNNYNAYESYKY------PGMFIALSKNGKTKKGNRVSPTMKVTHFLPR 205


>gi|222144221 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)

Query: 17  SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 76
           S  G+FL++ PDGT+DGT+D +  +    L    +  V I+  +   Y+AM+ +G LY S
Sbjct: 32  SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91

Query: 77  DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 136
                EC F E + EN+Y  Y S    ++ + + WF+GL K G   +G R    + +  F
Sbjct: 92  QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147

Query: 137 VPKPI 141
           +P P+
Sbjct: 148 LPLPV 152


>gi|4503697 fibroblast growth factor 1 (acidic) isoform 1 proprotein
           [Homo sapiens]
          Length = 155

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)

Query: 17  SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 76
           S  G+FL++ PDGT+DGT+D +  +    L    +  V I+  +   Y+AM+ +G LY S
Sbjct: 32  SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91

Query: 77  DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 136
                EC F E + EN+Y  Y S    ++ + + WF+GL K G   +G R    + +  F
Sbjct: 92  QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147

Query: 137 VPKPI 141
           +P P+
Sbjct: 148 LPLPV 152


>gi|222144273 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)

Query: 17  SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 76
           S  G+FL++ PDGT+DGT+D +  +    L    +  V I+  +   Y+AM+ +G LY S
Sbjct: 32  SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91

Query: 77  DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 136
                EC F E + EN+Y  Y S    ++ + + WF+GL K G   +G R    + +  F
Sbjct: 92  QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147

Query: 137 VPKPI 141
           +P P+
Sbjct: 148 LPLPV 152


>gi|222144271 fibroblast growth factor 1 (acidic) isoform 1
           proprotein [Homo sapiens]
          Length = 155

 Score = 80.1 bits (196), Expect = 1e-15
 Identities = 42/125 (33%), Positives = 67/125 (53%), Gaps = 4/125 (3%)

Query: 17  SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 76
           S  G+FL++ PDGT+DGT+D +  +    L    +  V I+  +   Y+AM+ +G LY S
Sbjct: 32  SNGGHFLRILPDGTVDGTRDRSDQHIQLQLSAESVGEVYIKSTETGQYLAMDTDGLLYGS 91

Query: 77  DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHF 136
                EC F E + EN+Y  Y S    ++ + + WF+GL K G   +G R    + +  F
Sbjct: 92  QTPNEECLFLERLEENHYNTYIS----KKHAEKNWFVGLKKNGSCKRGPRTHYGQKAILF 147

Query: 137 VPKPI 141
           +P P+
Sbjct: 148 LPLPV 152


>gi|153285461 fibroblast growth factor 2 [Homo sapiens]
          Length = 288

 Score = 71.2 bits (173), Expect = 4e-13
 Identities = 39/119 (32%), Positives = 64/119 (53%), Gaps = 6/119 (5%)

Query: 20  GYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVF 79
           G+FL++HPDG +DG ++++  +    L      VV+I+GV A+ Y+AM  +G L +S   
Sbjct: 171 GFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCV 230

Query: 80  TPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 138
           T EC F E +  N Y  Y S  Y       +W++ L + GQ   G++    + +  F+P
Sbjct: 231 TDECFFFERLESNNYNTYRSRKY------TSWYVALKRTGQYKLGSKTGPGQKAILFLP 283


>gi|4826726 fibroblast growth factor 19 precursor [Homo sapiens]
          Length = 216

 Score = 49.7 bits (117), Expect = 1e-06
 Identities = 35/118 (29%), Positives = 61/118 (51%), Gaps = 10/118 (8%)

Query: 22  FLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTP 81
           FL++  DG +D  + +++ ++L  +  V LR VAI+GV +  Y+ M  +G +     ++ 
Sbjct: 59  FLRIRADGVVDCARGQSA-HSLLEIKAVALRTVAIKGVHSVRYLCMGADGKMQGLLQYSE 117

Query: 82  E-CKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVP 138
           E C F+E +  + Y +Y S  +R   S     L   K+ Q+ K    +   P SHF+P
Sbjct: 118 EDCAFEEEIRPDGYNVYRSEKHRLPVS-----LSSAKQRQLYKN---RGFLPLSHFLP 167


>gi|10190674 fibroblast growth factor 23 precursor [Homo sapiens]
          Length = 251

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 6/105 (5%)

Query: 17  SQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSS 76
           ++  Y LQ+H +G +DG   +   Y+   +       V I GV +  Y+ M+  G ++ S
Sbjct: 47  ARNSYHLQIHKNGHVDGAPHQTI-YSALMIRSEDAGFVVITGVMSRRYLCMDFRGNIFGS 105

Query: 77  DVFTPE-CKFKESVFENYYVIYSSTLYR----QQESGRAWFLGLN 116
             F PE C+F+    EN Y +Y S  Y        + RA+  G+N
Sbjct: 106 HYFDPENCRFQHQTLENGYDVYHSPQYHFLVSLGRAKRAFLPGMN 150


>gi|9506597 fibroblast growth factor 21 precursor [Homo sapiens]
          Length = 209

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 28/78 (35%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 23  LQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPE 82
           L++  DGT+ G  D++ + +L  L  +   V+ I GVK S ++    +G LY S  F PE
Sbjct: 61  LEIREDGTVGGAADQSPE-SLLQLKALKPGVIQILGVKTSRFLCQRPDGALYGSLHFDPE 119

Query: 83  -CKFKESVFENYYVIYSS 99
            C F+E + E+ Y +Y S
Sbjct: 120 ACSFRELLLEDGYNVYQS 137


>gi|4503695 fibroblast growth factor 18 precursor [Homo sapiens]
          Length = 207

 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 7/87 (8%)

Query: 54  VAIQGVKASLYVAMNGEGYLYSS-DVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWF 112
           V I+G +   Y+ MN +G L    D  + EC F E V EN Y    S  Y        W+
Sbjct: 97  VRIKGKETEFYLCMNRKGKLVGKPDGTSKECVFIEKVLENNYTALMSAKYS------GWY 150

Query: 113 LGLNKEGQIMKGNRVKKTKPSSHFVPK 139
           +G  K+G+  KG + ++ +   HF+ +
Sbjct: 151 VGFTKKGRPRKGPKTRENQQDVHFMKR 177


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,266,655
Number of Sequences: 37866
Number of extensions: 325512
Number of successful extensions: 494
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 432
Number of HSP's gapped (non-prelim): 54
length of query: 181
length of database: 18,247,518
effective HSP length: 96
effective length of query: 85
effective length of database: 14,612,382
effective search space: 1242052470
effective search space used: 1242052470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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