Search of human proteins with 21536362

Search of human proteins with 21536362

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21536362 TBP-associated factor 1A isoform 2 [Homo sapiens]
         (336 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5032143 TBP-associated factor 1A isoform 1 [Homo sapiens]          696   0.0  
gi|21536362 TBP-associated factor 1A isoform 2 [Homo sapiens]         696   0.0  
gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]           30   3.0  
gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]             30   3.0  
gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]             30   3.0  
gi|186928850 mitochondrial ribosomal protein S27 [Homo sapiens]        29   5.2  
gi|24797143 sorting nexin 14 isoform b [Homo sapiens]                  28   8.9  
gi|24797145 sorting nexin 14 isoform a [Homo sapiens]                  28   8.9  

>gi|5032143 TBP-associated factor 1A isoform 1 [Homo sapiens]
          Length = 450

 Score =  696 bits (1797), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI 60
           MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI
Sbjct: 115 MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI 174

Query: 61  LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG 120
           LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG
Sbjct: 175 LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG 234

Query: 121 VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI 180
           VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI
Sbjct: 235 VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI 294

Query: 181 SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK 240
           SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK
Sbjct: 295 SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK 354

Query: 241 YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG 300
           YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG
Sbjct: 355 YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG 414

Query: 301 CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL 336
           CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL
Sbjct: 415 CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL 450


>gi|21536362 TBP-associated factor 1A isoform 2 [Homo sapiens]
          Length = 336

 Score =  696 bits (1797), Expect = 0.0
 Identities = 336/336 (100%), Positives = 336/336 (100%)

Query: 1   MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI 60
           MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI
Sbjct: 1   MESFNTFANRMKNIGVMNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREI 60

Query: 61  LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG 120
           LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG
Sbjct: 61  LINLIQAYKGLLQYYTWSEKKMELSKLDKDDYAYNAVAQDVFNHSWKTSANISALIKIPG 120

Query: 121 VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI 180
           VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI
Sbjct: 121 VWDPFVKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLI 180

Query: 181 SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK 240
           SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK
Sbjct: 181 SVLKILYQIVPSHKLMLEFHTLLRKSEKEEHRKLGLEVLFGVLDFAGCTKNITAWKYLAK 240

Query: 241 YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG 300
           YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG
Sbjct: 241 YLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSDWKEDTALACEKAFVAGLLLGKG 300

Query: 301 CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL 336
           CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL
Sbjct: 301 CRYFRYILKQDHQILGKKIKRMKRSVKKYSIVNPRL 336


>gi|31083053 ceroid-lipofuscinosis, neuronal 8 [Homo sapiens]
          Length = 286

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 5/61 (8%)

Query: 219 LFGVLDFAGCTKNITAWKYLAKYLKNILMGNHLAWVQEEWNSRKNWWPGFHFSYFWAKSD 278
           LF  L F GC  N+ A  YLA  +  +L+     +    W   K  W     S FW  + 
Sbjct: 140 LFAFLGFLGCLVNLQAGHYLA--MTTLLLEMSTPFTCVSWMLLKAGWSE---SLFWKLNQ 194

Query: 279 W 279
           W
Sbjct: 195 W 195


>gi|190014625 DIS3 mitotic control isoform b [Homo sapiens]
          Length = 928

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 13/46 (28%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 17  MNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREILI 62
           ++ L+  ++   YL   G  + ++ N  EA  W HG+N  ++EI++
Sbjct: 204 LSKLQQGIKSGTYL--QGTFRASRENYLEATVWIHGDNEENKEIIL 247


>gi|190014623 DIS3 mitotic control isoform a [Homo sapiens]
          Length = 958

 Score = 30.0 bits (66), Expect = 3.0
 Identities = 13/46 (28%), Positives = 26/46 (56%), Gaps = 2/46 (4%)

Query: 17  MNYLKISLQHALYLLHHGMLKDAKRNLSEAETWRHGENTSSREILI 62
           ++ L+  ++   YL   G  + ++ N  EA  W HG+N  ++EI++
Sbjct: 234 LSKLQQGIKSGTYL--QGTFRASRENYLEATVWIHGDNEENKEIIL 277


>gi|186928850 mitochondrial ribosomal protein S27 [Homo sapiens]
          Length = 414

 Score = 29.3 bits (64), Expect = 5.2
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 9/102 (8%)

Query: 126 VKSYVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLISVLKI 185
           + +++     Y  +D A   L N      FP N   ++ + +F+K++   +  L  V ++
Sbjct: 109 IHTWIRQCLKYDAQDKALYTLVNKVQYGIFPDNFTFNLLMDSFIKKENY-KDALSVVFEV 167

Query: 186 LYQ---IVPSHKLM---LEFHTLLRKSE--KEEHRKLGLEVL 219
           + Q    VPS +L+   + FH L +K++   EE R  G  +L
Sbjct: 168 MMQEAFEVPSTQLLSLYVLFHCLAKKTDFSWEEERNFGASLL 209


>gi|24797143 sorting nexin 14 isoform b [Homo sapiens]
          Length = 893

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 129 YVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLISVLKI-LY 187
           ++  L+F  D D    +L  +  D            L  FL++   PR+K  SVLK+ L 
Sbjct: 235 FLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELK 294

Query: 188 QIVPSHKLMLEFHTLLRK 205
           QI     L+  F   L++
Sbjct: 295 QIREQQDLLFRFMNFLKQ 312


>gi|24797145 sorting nexin 14 isoform a [Homo sapiens]
          Length = 946

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 1/78 (1%)

Query: 129 YVEMLEFYGDRDGAQEVLTNYAYDEKFPSNPNAHIYLYNFLKRQKAPRSKLISVLKI-LY 187
           ++  L+F  D D    +L  +  D            L  FL++   PR+K  SVLK+ L 
Sbjct: 279 FLPSLDFLADPDTVNHLLIIFIDDSPPEKATEPASPLVPFLQKFAEPRNKKPSVLKLELK 338

Query: 188 QIVPSHKLMLEFHTLLRK 205
           QI     L+  F   L++
Sbjct: 339 QIREQQDLLFRFMNFLKQ 356


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,407,025
Number of Sequences: 37866
Number of extensions: 524339
Number of successful extensions: 1151
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1147
Number of HSP's gapped (non-prelim): 8
length of query: 336
length of database: 18,247,518
effective HSP length: 103
effective length of query: 233
effective length of database: 14,347,320
effective search space: 3342925560
effective search space used: 3342925560
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.