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Search of human proteins with 21464127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 662 0.0
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 539 e-153
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 268 6e-72
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 268 6e-72
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 268 6e-72
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 257 8e-69
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 256 2e-68
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 247 1e-65
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 247 1e-65
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 247 1e-65
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 245 3e-65
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 244 5e-65
gi|11496281 kallikrein 13 precursor [Homo sapiens] 243 2e-64
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 234 7e-62
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 234 7e-62
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 230 1e-60
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 224 1e-58
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 224 1e-58
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 216 2e-56
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 213 2e-55
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 213 2e-55
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 213 2e-55
gi|21464129 kallikrein 8 isoform 3 [Homo sapiens] 212 4e-55
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 210 1e-54
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 209 3e-54
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 199 2e-51
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 199 2e-51
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 199 2e-51
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 198 4e-51
gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo s... 197 7e-51
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 662 bits (1708), Expect = 0.0
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWR 60
MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWR
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWR 60
Query: 61 SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 120
SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK
Sbjct: 61 SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 120
Query: 121 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 180
KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK
Sbjct: 121 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 180
Query: 181 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 240
VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG
Sbjct: 181 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 240
Query: 241 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 300
MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI
Sbjct: 241 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 300
Query: 301 IGSKG 305
IGSKG
Sbjct: 301 IGSKG 305
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 539 bits (1389), Expect = e-153
Identities = 260/305 (85%), Positives = 260/305 (85%), Gaps = 45/305 (14%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWAACGSLDLLTKLYAENLPCVHLNPQWPSQPSHCPRGWR 60
MGRPRPRAAKTWMFLLLLGGAWA
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWA------------------------------------- 23
Query: 61 SNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 120
GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK
Sbjct: 24 --------GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCK 75
Query: 121 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 180
KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK
Sbjct: 76 KPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSK 135
Query: 181 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 240
VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG
Sbjct: 136 VKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDG 195
Query: 241 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 300
MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI
Sbjct: 196 MVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKI 255
Query: 301 IGSKG 305
IGSKG
Sbjct: 256 IGSKG 260
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 268 bits (684), Expect = 6e-72
Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
E +++ G EC+PHSQPWQAALF+ +LLCG L+ W+LTAAHC KP+Y V LG H+LQ
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 135 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193
++G EQ +S PHP +N+S +DH +D+ML+++ S+ V+P++L+ C
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 252
G C +SGWG+ +SP+ P TL CA + I +KCE+AYPG ITD MVCA +G D+
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299
CQGDSGGPLVC+ +LQGI SWG DPC + KPGVYT +C+Y+DWI++
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 245
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 268 bits (684), Expect = 6e-72
Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
E +++ G EC+PHSQPWQAALF+ +LLCG L+ W+LTAAHC KP+Y V LG H+LQ
Sbjct: 51 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 110
Query: 135 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193
++G EQ +S PHP +N+S +DH +D+ML+++ S+ V+P++L+ C
Sbjct: 111 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 170
Query: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 252
G C +SGWG+ +SP+ P TL CA + I +KCE+AYPG ITD MVCA +G D+
Sbjct: 171 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 230
Query: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299
CQGDSGGPLVC+ +LQGI SWG DPC + KPGVYT +C+Y+DWI++
Sbjct: 231 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 277
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 268 bits (684), Expect = 6e-72
Identities = 117/227 (51%), Positives = 160/227 (70%), Gaps = 2/227 (0%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
E +++ G EC+PHSQPWQAALF+ +LLCG L+ W+LTAAHC KP+Y V LG H+LQ
Sbjct: 19 ETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAHCLKPRYIVHLGQHNLQ 78
Query: 135 NKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193
++G EQ +S PHP +N+S +DH +D+ML+++ S+ V+P++L+ C
Sbjct: 79 KEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSITWAVRPLTLSSRCVTA 138
Query: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DT 252
G C +SGWG+ +SP+ P TL CA + I +KCE+AYPG ITD MVCA +G D+
Sbjct: 139 GTSCLISGWGSTSSPQLRLPHTLRCANITIIEHQKCENAYPGNITDTMVCASVQEGGKDS 198
Query: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299
CQGDSGGPLVC+ +LQGI SWG DPC + KPGVYT +C+Y+DWI++
Sbjct: 199 CQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGVYTKVCKYVDWIQE 245
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 257 bits (657), Expect = 8e-69
Identities = 118/236 (50%), Positives = 156/236 (66%), Gaps = 3/236 (1%)
Query: 68 AGHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVR 127
AGH A + + +G EC+P+SQPWQA LF +L CG L+ W+LTAAHC+KP VR
Sbjct: 14 AGHGWA-DTRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAHCRKPYLWVR 72
Query: 128 LGDHSLQNKDGPEQEIPVVQSIPHPCYNSS-DVEDHNHDLMLLQLRDQASLGSKVKPISL 186
LG+H L +GPEQ V PHP +N DHN D+ML++L QA L V+P++L
Sbjct: 73 LGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARLSPAVQPLNL 132
Query: 187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 246
+ C PG +C +SGWG V+SP+ FP TL CA + I K C AYPG I+D M+CAG
Sbjct: 133 SQTCVSPGMQCLISGWGAVSSPKALFPVTLQCANISILENKLCHWAYPGHISDSMLCAGL 192
Query: 247 SKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
+G +CQGDSGGPLVC+G L G+ S G++PC R +P VYT++C YLDWI++I+
Sbjct: 193 WEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAVYTSVCHYLDWIQEIM 248
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 256 bits (654), Expect = 2e-68
Identities = 123/260 (47%), Positives = 161/260 (61%), Gaps = 6/260 (2%)
Query: 48 WPSQPSHCPRGWRSNPLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQG--QQLLCGG 105
WPS P L A S+ E+K++GGH C SQPWQAAL G ++ LCGG
Sbjct: 11 WPSAPKMFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGG 70
Query: 106 VLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHD 165
L+ G WV+TAAHC +P V LG H+L+ + +Q + VV+ + HP YNS H++D
Sbjct: 71 ALLSGQWVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNS---RTHDND 127
Query: 166 LMLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFP 225
LMLLQL+ A +G V+PI + C PG C VSGWGT++SP +P +L C + I P
Sbjct: 128 LMLLQLQQPARIGRAVRPIEVTQACASPGTSCRVSGWGTISSPIARYPASLQCVNINISP 187
Query: 226 QKKCEDAYPGQITDGMVCAGSSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKP 284
+ C+ AYP IT GMVCAG +G D+CQGDSGGPLVC G LQG+ SWG + C P
Sbjct: 188 DEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGYP 247
Query: 285 GVYTNICRYLDWIKKIIGSK 304
GVYTN+C+Y WI++ + K
Sbjct: 248 GVYTNLCKYRSWIEETMRDK 267
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 247 bits (630), Expect = 1e-65
Identities = 118/255 (46%), Positives = 161/255 (63%), Gaps = 8/255 (3%)
Query: 52 PSHCPRGWRSNPLPPAAGHSRAQED---KVLGGHECQPHSQPWQAALF-QGQQLLCGGVL 107
PS+ + L AG +D +++ G +C H+QPWQAAL + QL CG VL
Sbjct: 38 PSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVL 97
Query: 108 VGGNWVLTAAHCKKPKYTVRLGDHSLQNK-DGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 166
V W+LTAAHC+K + VRLG +SL + +Q V+SIPHP Y+ H++DL
Sbjct: 98 VHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG---HSNDL 154
Query: 167 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 226
ML++L + V+PI+++ HC G KC VSGWGT SP+ +FP L C + + Q
Sbjct: 155 MLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQ 214
Query: 227 KKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGV 286
K+CEDAYP QI D M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGV
Sbjct: 215 KRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGV 274
Query: 287 YTNICRYLDWIKKII 301
YTN+C++ WI++ I
Sbjct: 275 YTNLCKFTKWIQETI 289
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 247 bits (630), Expect = 1e-65
Identities = 118/255 (46%), Positives = 161/255 (63%), Gaps = 8/255 (3%)
Query: 52 PSHCPRGWRSNPLPPAAGHSRAQED---KVLGGHECQPHSQPWQAALF-QGQQLLCGGVL 107
PS+ + L AG +D +++ G +C H+QPWQAAL + QL CG VL
Sbjct: 38 PSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVL 97
Query: 108 VGGNWVLTAAHCKKPKYTVRLGDHSLQNK-DGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 166
V W+LTAAHC+K + VRLG +SL + +Q V+SIPHP Y+ H++DL
Sbjct: 98 VHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG---HSNDL 154
Query: 167 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 226
ML++L + V+PI+++ HC G KC VSGWGT SP+ +FP L C + + Q
Sbjct: 155 MLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQ 214
Query: 227 KKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGV 286
K+CEDAYP QI D M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGV
Sbjct: 215 KRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGV 274
Query: 287 YTNICRYLDWIKKII 301
YTN+C++ WI++ I
Sbjct: 275 YTNLCKFTKWIQETI 289
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 247 bits (630), Expect = 1e-65
Identities = 118/255 (46%), Positives = 161/255 (63%), Gaps = 8/255 (3%)
Query: 52 PSHCPRGWRSNPLPPAAGHSRAQED---KVLGGHECQPHSQPWQAALF-QGQQLLCGGVL 107
PS+ + L AG +D +++ G +C H+QPWQAAL + QL CG VL
Sbjct: 38 PSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVL 97
Query: 108 VGGNWVLTAAHCKKPKYTVRLGDHSLQNK-DGPEQEIPVVQSIPHPCYNSSDVEDHNHDL 166
V W+LTAAHC+K + VRLG +SL + +Q V+SIPHP Y+ H++DL
Sbjct: 98 VHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPG---HSNDL 154
Query: 167 MLLQLRDQASLGSKVKPISLADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQ 226
ML++L + V+PI+++ HC G KC VSGWGT SP+ +FP L C + + Q
Sbjct: 155 MLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQ 214
Query: 227 KKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGV 286
K+CEDAYP QI D M CAG G D+CQGDSGGP+VC+G+LQG+ SWG PC R ++PGV
Sbjct: 215 KRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGV 274
Query: 287 YTNICRYLDWIKKII 301
YTN+C++ WI++ I
Sbjct: 275 YTNLCKFTKWIQETI 289
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 245 bits (626), Expect = 3e-65
Identities = 115/235 (48%), Positives = 154/235 (65%), Gaps = 14/235 (5%)
Query: 76 DKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQN 135
DK+L G EC PHSQPWQ AL++ + CG L+ +WVL+AAHC+ VRLG+H+L+
Sbjct: 20 DKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79
Query: 136 KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
+DGPEQ + IPHP Y + H +D+MLL+L A L +V+P L C PG+
Sbjct: 80 RDGPEQLRTTSRVIPHPRY---EARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
Query: 196 KCTVSGWGTVT--------SPRE--NFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG 245
C VSGWG V+ SPR + PDTL+CA + I C+ +YPG++T+ MVCAG
Sbjct: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
Query: 246 S-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299
+ +GA++C+GDSGGPLVC G LQGI SWG PC + KPGVYT +C YL+WI++
Sbjct: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 251
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 244 bits (624), Expect = 5e-65
Identities = 119/234 (50%), Positives = 142/234 (60%), Gaps = 2/234 (0%)
Query: 69 GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRL 128
G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAAHC +Y VRL
Sbjct: 13 GLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRL 72
Query: 129 GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLAD 188
G+HSL D EQ S+ HP Y + H HDL LL+LR + S V+P+ L +
Sbjct: 73 GEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRVTSSVQPLPLPN 131
Query: 189 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK 248
C G +C VSGWG PR FPD L C + I C YPG+IT MVCAG
Sbjct: 132 DCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP 191
Query: 249 GADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNICRYLDWIKKII 301
G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC+Y+DWI+ I+
Sbjct: 192 GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYICKYVDWIRMIM 245
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 243 bits (619), Expect = 2e-64
Identities = 116/225 (51%), Positives = 151/225 (67%), Gaps = 3/225 (1%)
Query: 80 GGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGP 139
GG+ C PHSQPWQAAL +LLCGGVLV WVLTAAHC K V LG H+L +
Sbjct: 38 GGYTCFPHSQPWQAALLVQGRLLCGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAG 97
Query: 140 EQEIPVVQSIPHPCYNSSDVE-DHNHDLMLLQLRDQASLGSKVKPISLA-DHCTQPGQKC 197
EQ VV SIPHP Y S +H+HD+MLL+L+ L ++ + L+ ++ PG C
Sbjct: 98 EQVREVVHSIPHPEYRRSPTHLNHDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTC 157
Query: 198 TVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQGD 256
VSGWGT TSP+ N+P TL CA +++ ++C YPG+ITD M+CAG+ +G D+C+GD
Sbjct: 158 RVSGWGTTTSPQVNYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGD 217
Query: 257 SGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
SGGPLVC+ L GI SWG PCG+ D+PGVYT + RY+ WI++ I
Sbjct: 218 SGGPLVCNRTLYGIVSWGDFPCGQPDRPGVYTRVSRYVLWIRETI 262
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 234 bits (597), Expect = 7e-62
Identities = 109/232 (46%), Positives = 152/232 (65%), Gaps = 6/232 (2%)
Query: 74 QEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 133
+++K++ G C S P+QAAL+ LLCGGVL+ WVLTAAHCKKP V LG H+L
Sbjct: 18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL 77
Query: 134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193
+ ++ +++ VV+++ HP Y D H+ D+MLL+L A L ++P+ L C+
Sbjct: 78 RQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134
Query: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK-GADT 252
C + GWG +FPDT+ CA + + +++CE AYPGQIT M+CAG K G D+
Sbjct: 135 TTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192
Query: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 304
CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY +WI+K I +K
Sbjct: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 244
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 234 bits (597), Expect = 7e-62
Identities = 109/232 (46%), Positives = 152/232 (65%), Gaps = 6/232 (2%)
Query: 74 QEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSL 133
+++K++ G C S P+QAAL+ LLCGGVL+ WVLTAAHCKKP V LG H+L
Sbjct: 18 EQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNL 77
Query: 134 QNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP 193
+ ++ +++ VV+++ HP Y D H+ D+MLL+L A L ++P+ L C+
Sbjct: 78 RQRESSQEQSSVVRAVIHPDY---DAASHDQDIMLLRLARPAKLSELIQPLPLERDCSAN 134
Query: 194 GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK-GADT 252
C + GWG +FPDT+ CA + + +++CE AYPGQIT M+CAG K G D+
Sbjct: 135 TTSCHILGWGKTADG--DFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYGKDS 192
Query: 253 CQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSK 304
CQGDSGGPLVC L+G+ SWG+ PCG +KPGVYTN+CRY +WI+K I +K
Sbjct: 193 CQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 244
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 230 bits (587), Expect = 1e-60
Identities = 114/224 (50%), Positives = 133/224 (59%), Gaps = 2/224 (0%)
Query: 69 GHSRAQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRL 128
G S+A K+ G EC +SQPWQ LF+G L CGGVL+ WVLTAAHC +Y VRL
Sbjct: 13 GLSQAATPKIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAHCSGSRYWVRL 72
Query: 129 GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLAD 188
G+HSL D EQ S+ HP Y + H HDL LL+LR + S V+P+ L +
Sbjct: 73 GEHSLSQLDWTEQIRHSGFSVTHPGYLGASTS-HEHDLRLLRLRLPVRVTSSVQPLPLPN 131
Query: 189 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSK 248
C G +C VSGWG PR FPD L C + I C YPG+IT MVCAG
Sbjct: 132 DCATAGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGRITSNMVCAGGVP 191
Query: 249 GADTCQGDSGGPLVCDGALQGITSWGS-DPCGRSDKPGVYTNIC 291
G D CQGDSGGPLVC G LQG+ SWGS PCG+ PGVYT IC
Sbjct: 192 GQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVYTYIC 235
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 224 bits (570), Expect = 1e-58
Identities = 112/228 (49%), Positives = 139/228 (60%), Gaps = 10/228 (4%)
Query: 73 AQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHS 132
AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAAHCK +YTV LG +
Sbjct: 25 AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84
Query: 133 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ 192
L ++ Q I +S HP Y++ + H +DLML++L QA L S VK + L C
Sbjct: 85 LGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139
Query: 193 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG---SSKG 249
PG CTVSGWGT TSP FP L C +VK+ + C Y + + M+CAG S K
Sbjct: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199
Query: 250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297
A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ WI
Sbjct: 200 A--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 224 bits (570), Expect = 1e-58
Identities = 112/228 (49%), Positives = 139/228 (60%), Gaps = 10/228 (4%)
Query: 73 AQEDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHS 132
AQ DK++ G C S PWQ AL G QL CGGVLV WVLTAAHCK +YTV LG +
Sbjct: 25 AQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDT 84
Query: 133 LQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQ 192
L ++ Q I +S HP Y++ + H +DLML++L QA L S VK + L C
Sbjct: 85 LGDRRA--QRIKASKSFRHPGYST---QTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEP 139
Query: 193 PGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG---SSKG 249
PG CTVSGWGT TSP FP L C +VK+ + C Y + + M+CAG S K
Sbjct: 140 PGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKN 199
Query: 250 ADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWI 297
A C GDSGGPLVC G LQG+ SWG+ PCG+ + PGVYT +C++ WI
Sbjct: 200 A--CNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWI 245
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 216 bits (551), Expect = 2e-56
Identities = 104/237 (43%), Positives = 145/237 (61%), Gaps = 10/237 (4%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+ +++GG EC+ HSQPWQAAL+ CGG+LV WVLTAAHC Y + LG H+L
Sbjct: 22 QSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLF 81
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDH--------NHDLMLLQLRDQA-SLGSKVKPIS 185
+ + Q + V +S PHP +N S +E+H +HDLMLL+L + A ++ VK +
Sbjct: 82 DDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVE 141
Query: 186 LADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG 245
L + G C SGWG++ +FPD L C ++KI P +C+ A+ ++TD M+C G
Sbjct: 142 LPTEEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVG 201
Query: 246 SSKGA-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
+G DTC GDSGGPL+CDG LQG+TSWG PCG +KP V + Y+ WI+ I
Sbjct: 202 HLEGGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTI 258
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 2e-55
Identities = 105/228 (46%), Positives = 130/228 (57%), Gaps = 6/228 (2%)
Query: 81 GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPE 140
G C SQPWQ +LF G C GVLV +WVLTAAHC R+GD L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 141 QEIPVVQSIPHPCYNSSDV-----EDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Q +S+ HP Y+ HDLMLL+L LG +V+ + L C QPG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQG 255
+C V+GWGT + R + L C+ + I K+CE YPG +T+ M+CAG +G D CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
DSGGPLVCD LQGI SWG PCG + P VYT IC+Y+ WI K+I S
Sbjct: 228 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 2e-55
Identities = 105/228 (46%), Positives = 130/228 (57%), Gaps = 6/228 (2%)
Query: 81 GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPE 140
G C SQPWQ +LF G C GVLV +WVLTAAHC R+GD L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 141 QEIPVVQSIPHPCYNSSDV-----EDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Q +S+ HP Y+ HDLMLL+L LG +V+ + L C QPG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQG 255
+C V+GWGT + R + L C+ + I K+CE YPG +T+ M+CAG +G D CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
DSGGPLVCD LQGI SWG PCG + P VYT IC+Y+ WI K+I S
Sbjct: 228 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 213 bits (542), Expect = 2e-55
Identities = 105/228 (46%), Positives = 130/228 (57%), Gaps = 6/228 (2%)
Query: 81 GHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKDGPE 140
G C SQPWQ +LF G C GVLV +WVLTAAHC R+GD L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 141 QEIPVVQSIPHPCYNSSDV-----EDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Q +S+ HP Y+ HDLMLL+L LG +V+ + L C QPG
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQG 255
+C V+GWGT + R + L C+ + I K+CE YPG +T+ M+CAG +G D CQ
Sbjct: 168 QCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQS 227
Query: 256 DSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
DSGGPLVCD LQGI SWG PCG + P VYT IC+Y+ WI K+I S
Sbjct: 228 DSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRS 275
>gi|21464129 kallikrein 8 isoform 3 [Homo sapiens]
Length = 119
Score = 212 bits (539), Expect = 4e-55
Identities = 96/96 (100%), Positives = 96/96 (100%)
Query: 210 ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG 269
ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG
Sbjct: 24 ENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGADTCQGDSGGPLVCDGALQG 83
Query: 270 ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 305
ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG
Sbjct: 84 ITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 119
Score = 53.5 bits (127), Expect = 2e-07
Identities = 23/23 (100%), Positives = 23/23 (100%)
Query: 1 MGRPRPRAAKTWMFLLLLGGAWA 23
MGRPRPRAAKTWMFLLLLGGAWA
Sbjct: 1 MGRPRPRAAKTWMFLLLLGGAWA 23
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 210 bits (535), Expect = 1e-54
Identities = 99/230 (43%), Positives = 144/230 (62%), Gaps = 6/230 (2%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 21 DDKIVGGYNCEENSVPYQVSLNSGYHF-CGGSLINEQWVVSAGHCYKSRIQVRLGEHNIE 79
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
+G EQ I + I HP Y+ + N+D+ML++L +A + ++V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPQYDRKTL---NNDIMLIKLSSRAVINARVSTISLPTAPPATG 136
Query: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
KC +SGWG S ++PD L C + + Q KCE +YPG+IT M C G +G D+C
Sbjct: 137 TKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSC 196
Query: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
QGDSGGP+VC+G LQG+ SWG D C + +KPGVYT + Y+ WIK I +
Sbjct: 197 QGDSGGPVVCNGQLQGVVSWG-DGCAQKNKPGVYTKVYNYVKWIKNTIAA 245
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 209 bits (531), Expect = 3e-54
Identities = 105/238 (44%), Positives = 136/238 (57%), Gaps = 9/238 (3%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+ +++GG EC+ HSQPWQ A++ CGGVLV WVLTAAHC K V LG H+L
Sbjct: 22 QSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLF 81
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISL 186
+ Q +PV S PHP YN S + ED +HDLMLL+L + A + VK + L
Sbjct: 82 EPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGL 141
Query: 187 ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS 246
G C SGWG++ P +L C + + C AY ++T+ M+CAG
Sbjct: 142 PTQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGL 201
Query: 247 -SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
+ G DTC GDSGGPLVC+G LQGITSWG +PC +KP VYT + Y WIK I +
Sbjct: 202 WTGGKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAA 259
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 199 bits (507), Expect = 2e-51
Identities = 99/234 (42%), Positives = 133/234 (56%), Gaps = 9/234 (3%)
Query: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136
+++GG EC+ HSQPWQ + + +CGGVLV WVLTAAHC + K + LG HSL +
Sbjct: 24 RIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHP 83
Query: 137 DGPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLAD 188
+ Q V S PHP Y+ S + +D +HDLMLL+L + A L VK + L
Sbjct: 84 EDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPT 143
Query: 189 HCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGS-S 247
G C SGWG++ P L C ++ + C +P ++T M+CAG +
Sbjct: 144 QEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWT 203
Query: 248 KGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
G TC GDSGGPLVC+G LQGITSWGS+PC ++P +YT + Y WIK I
Sbjct: 204 GGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTI 257
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 78 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 136
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 137 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 193
Query: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 194 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 253
Query: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 254 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 302
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 199 bits (507), Expect = 2e-51
Identities = 95/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++AAHC K + VRLG+H+++
Sbjct: 21 DDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNIK 79
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
+G EQ I + I HP YN +++ D+ML++L A + ++V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPKYNRDTLDN---DIMLIKLSSPAVINARVSTISLPTAPPAAG 136
Query: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
+C +SGWG S ++PD L C + + Q +C+ +YPG+IT+ M C G +G D+C
Sbjct: 137 TECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEGGKDSC 196
Query: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
Q DSGGP+VC+G LQG+ SWG C ++PGVYT + Y+DWIK I +
Sbjct: 197 QRDSGGPVVCNGQLQGVVSWGHG-CAWKNRPGVYTKVYNYVDWIKDTIAA 245
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 198 bits (504), Expect = 4e-51
Identities = 96/230 (41%), Positives = 143/230 (62%), Gaps = 6/230 (2%)
Query: 75 EDKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQ 134
+DK++GG+ C+ +S P+Q +L G CGG L+ WV++A HC K + VRLG+H+++
Sbjct: 21 DDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVVSAGHCYKSRIQVRLGEHNIE 79
Query: 135 NKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPG 194
+G EQ I + I HP YNS +++ D++L++L A + S+V ISL G
Sbjct: 80 VLEGNEQFINAAKIIRHPKYNSRTLDN---DILLIKLSSPAVINSRVSAISLPTAPPAAG 136
Query: 195 QKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTC 253
+ +SGWG S ++PD L C + + Q +CE +YPG+IT+ M C G +G D+C
Sbjct: 137 TESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASYPGKITNNMFCVGFLEGGKDSC 196
Query: 254 QGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGS 303
QGDSGGP+V +G LQGI SWG C + ++PGVYT + Y+DWIK I +
Sbjct: 197 QGDSGGPVVSNGELQGIVSWGYG-CAQKNRPGVYTKVYNYVDWIKDTIAA 245
>gi|89142741 kallikrein-related peptidase 4 preproprotein [Homo
sapiens]
Length = 254
Score = 197 bits (502), Expect = 7e-51
Identities = 96/227 (42%), Positives = 132/227 (58%), Gaps = 7/227 (3%)
Query: 77 KVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNK 136
+++ G +C PHSQPWQAAL +L C GVLV WVL+AAHC + YT+ LG HSL+
Sbjct: 30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEAD 89
Query: 137 DGP-EQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
P Q + S+ HP YN + + DLML++L + S ++ IS+A C G
Sbjct: 90 QEPGSQMVEASLSVRHPEYNRPLLAN---DLMLIKLDESVSESDTIRSISIASQCPTAGN 146
Query: 196 KCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKGA-DTCQ 254
C VSGWG + + R P L C V + ++ C Y M CAG D+C
Sbjct: 147 SCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGHDQKDSCN 204
Query: 255 GDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKII 301
GDSGGPL+C+G LQG+ S+G PCG+ PGVYTN+C++ +WI+K +
Sbjct: 205 GDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 251
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.458
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,903,121
Number of Sequences: 37866
Number of extensions: 759070
Number of successful extensions: 2615
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1898
Number of HSP's gapped (non-prelim): 252
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.