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Search of human proteins with 21361557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361557 vasoactive intestinal peptide receptor 2 [Homo
sapiens]
(438 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens] 906 0.0
gi|29171759 adenylate cyclase activating polypeptide 1 (pituitar... 437 e-123
gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens] 392 e-109
gi|114205383 secretin receptor precursor [Homo sapiens] 385 e-107
gi|58530851 growth hormone releasing hormone receptor isoform a ... 338 6e-93
gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens] 285 4e-77
gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens] 264 1e-70
gi|58530853 growth hormone releasing hormone receptor isoform b ... 258 7e-69
gi|4758438 glucagon-like peptide 2 receptor precursor [Homo sapi... 258 1e-68
gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens] 250 2e-66
gi|4503947 glucagon receptor [Homo sapiens] 247 1e-65
gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens] 244 1e-64
gi|19923245 corticotropin releasing hormone receptor 1 isoform 2... 182 4e-46
gi|32307159 corticotropin releasing hormone receptor 2 [Homo sap... 180 3e-45
gi|223717971 corticotropin releasing hormone receptor 1 isoform ... 167 2e-41
gi|223717978 corticotropin releasing hormone receptor 1 isoform ... 166 3e-41
gi|4502547 calcitonin receptor [Homo sapiens] 160 2e-39
gi|5031621 calcitonin receptor-like [Homo sapiens] 155 7e-38
gi|223717985 corticotropin releasing hormone receptor 1 isoform ... 153 3e-37
gi|45433552 G protein-coupled receptor 133 [Homo sapiens] 95 1e-19
gi|163792198 latrophilin 3 precursor [Homo sapiens] 80 5e-15
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens] 77 3e-14
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens] 77 3e-14
gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens] 75 1e-13
gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens] 75 1e-13
gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens] 75 1e-13
gi|23397681 egf-like module containing, mucin-like, hormone rece... 74 2e-13
gi|23397693 egf-like module containing, mucin-like, hormone rece... 74 2e-13
gi|23397691 egf-like module containing, mucin-like, hormone rece... 74 2e-13
gi|23397689 egf-like module containing, mucin-like, hormone rece... 74 2e-13
>gi|21361557 vasoactive intestinal peptide receptor 2 [Homo sapiens]
Length = 438
Score = 906 bits (2342), Expect = 0.0
Identities = 438/438 (100%), Positives = 438/438 (100%)
Query: 1 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT 60
MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT
Sbjct: 1 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNIT 60
Query: 61 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI 120
CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI
Sbjct: 61 CWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKI 120
Query: 121 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD 180
TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD
Sbjct: 121 TFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKD 180
Query: 181 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC 240
DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC
Sbjct: 181 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC 240
Query: 241 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI 300
FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI
Sbjct: 241 FLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI 300
Query: 301 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE 360
SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE
Sbjct: 301 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE 360
Query: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ 420
LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ
Sbjct: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSFSRNGSEGALQ 420
Query: 421 FHRGSRAQSFLQTETSVI 438
FHRGSRAQSFLQTETSVI
Sbjct: 421 FHRGSRAQSFLQTETSVI 438
>gi|29171759 adenylate cyclase activating polypeptide 1 (pituitary)
receptor type I precursor [Homo sapiens]
Length = 468
Score = 437 bits (1124), Expect = e-123
Identities = 224/454 (49%), Positives = 293/454 (64%), Gaps = 39/454 (8%)
Query: 8 ALLTCWLLAPVNSIHPECRFHLEIQEEETKCAELLRSQTE------KHKACSGVWDNITC 61
+L LL ++H +C F ++E+ C E ++ E C G+WDNITC
Sbjct: 8 SLAALLLLPMAPAMHSDCIF----KKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITC 63
Query: 62 WRPANVGETVTVPCPKVFSNF-----------------------YSKAGNISKNCTSDGW 98
W+PA+VGE V V CP++F F S G +S+NCT DGW
Sbjct: 64 WKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGW 123
Query: 99 SETFPDFVDACGYSDPEDES--KITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHC 156
SE FP + DACG+ + E E+ + +Y+ VKA+YT+GYS SL++L T +ILC FRKLHC
Sbjct: 124 SEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHC 183
Query: 157 TRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMAN 216
TRN+IH+NLF+SF+LRAISV +KD +LY+ + HC S V CK +VF YC+++N
Sbjct: 184 TRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCF---ISTVECKAVMVFFHYCVVSN 240
Query: 217 FFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTN 275
+FWL +EGLYL TLLV P RR F Y +IGWG PTVC+ W RLY +DTGCWD N
Sbjct: 241 YFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMN 300
Query: 276 DHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIP 335
D + WWVI+ P++ SI+VNFVLFI II IL+QKL SPD+GGN+ S Y RLA+STLLLIP
Sbjct: 301 DSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIYLRLARSTLLLIP 360
Query: 336 LFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCP 395
LFG+HY VFA P ++S + +++FEL LGSFQG VVAVLYCFLN EVQ E+KRKWRS
Sbjct: 361 LFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAEIKRKWRSWKV 420
Query: 396 TPSASRDYRVCGSSFSRNGSEGALQFHRGSRAQS 429
+ D++ S + +G G Q S++ S
Sbjct: 421 NRYFAVDFKHRHPSLASSGVNGGTQLSILSKSSS 454
>gi|15619006 vasoactive intestinal peptide receptor 1 [Homo sapiens]
Length = 457
Score = 392 bits (1008), Expect = e-109
Identities = 210/447 (46%), Positives = 278/447 (62%), Gaps = 31/447 (6%)
Query: 13 WLLAPVNS----IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVG 68
W L P + EC + I+ + +C E + + E CS +WDN+TCW G
Sbjct: 21 WALGPAGGQAARLQEECDYVQMIEVQHKQCLEEAQLENETI-GCSKMWDNLTCWPATPRG 79
Query: 69 ETVTVPCPKVFSNFYSKAG-NISKNCTSDGWSETFPD-FVDACGYSDPE---DESKITFY 123
+ V + CP +F F S G N+S++CT +GW+ P + ACG D DE + FY
Sbjct: 80 QVVVLACPLIFKLFSSIQGRNVSRSCTDEGWTHLEPGPYPIACGLDDKAASLDEQQTMFY 139
Query: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL 183
VK YT+GY +SL +L + IL LFRKLHCTRNYIH++LF+SFILRA +V +KD L
Sbjct: 140 GSVKTGYTIGYGLSLATLLVATAILSLFRKLHCTRNYIHMHLFISFILRAAAVFIKDLAL 199
Query: 184 YSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFL 242
+ S + C + VGCK ++VF QYC+MANFFWLLVEGLYL+TLL V+ R+ F
Sbjct: 200 FDSGESDQCSEGS---VGCKAAMVFFQYCVMANFFWLLVEGLYLYTLLAVSFFSERKYFW 256
Query: 243 AYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISI 302
Y+LIGWG+P+ WT AR++ ED GCWDT + S+ WW+I+ PIL SI+VNF+LFI I
Sbjct: 257 GYILIGWGVPSTFTMVWTIARIHFEDYGCWDTINSSL-WWIIKGPILTSILVNFILFICI 315
Query: 303 IRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELC 362
IRILLQKL PD+ +D S Y RLA+STLLLIPLFGVHY++FA FP + + +++FEL
Sbjct: 316 IRILLQKLRPPDIRKSDSSPYSRLARSTLLLIPLFGVHYIMFAFFPDNFKPEVKMVFELV 375
Query: 363 LGSFQGLVVAVLYCFLNSEVQCELKRKWR-----------SRCPTPSASRDYRVCGSSFS 411
+GSFQG VVA+LYCFLN EVQ EL+RKWR + PS + C + S
Sbjct: 376 VGSFQGFVVAILYCFLNGEVQAELRRKWRRWHLQGVLGWNPKYRHPSGGSNGATCSTQVS 435
Query: 412 RNGSEGALQFHRGSRAQSFLQTETSVI 438
+ G+R S Q E S++
Sbjct: 436 M-----LTRVSPGARRSSSFQAEVSLV 457
>gi|114205383 secretin receptor precursor [Homo sapiens]
Length = 440
Score = 385 bits (989), Expect = e-107
Identities = 195/401 (48%), Positives = 266/401 (66%), Gaps = 15/401 (3%)
Query: 1 MRTLLPPALLTCWLLAPVNSIHPECRFHLEIQEEETKCA-ELLRSQT------EKHKACS 53
++ LL P LL C ++ C + EE+ +C EL R QT + C
Sbjct: 9 LQQLLLPVLLAC-AAHSTGALPRLCDVLQVLWEEQDQCLQELSREQTGDLGTEQPVPGCE 67
Query: 54 GVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDGWSETFPDFVDACGYS- 112
G+WDNI+CW + G V V CP+ S+ G++ +NCT DGWSETFP ACG +
Sbjct: 68 GMWDNISCWPSSVPGRMVEVECPRFLRMLTSRNGSLFRNCTQDGWSETFPRPNLACGVNV 127
Query: 113 -DPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFIL 171
D +E + ++ + +K +YT+GYS SL+ L ILC FR+LHCTRNYIH++LF+SFIL
Sbjct: 128 NDSSNEKRHSYLLKLKVMYTVGYSSSLVMLLVALGILCAFRRLHCTRNYIHMHLFVSFIL 187
Query: 172 RAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL 231
RA+S +KD VL+SS +C + GCKL +V QYCIMAN+ WLLVEGLYLHTLL
Sbjct: 188 RALSNFIKDAVLFSSDDVTYCDAHRA---GCKLVMVLFQYCIMANYSWLLVEGLYLHTLL 244
Query: 232 -VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILI 290
++ R+ ++ GWG P + + W AR +LED GCWD N ++ WW+IR P+++
Sbjct: 245 AISFFSERKYLQGFVAFGWGSPAIFVALWAIARHFLEDVGCWDINANASIWWIIRGPVIL 304
Query: 291 SIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPIS 350
SI++NF+LFI+I+RIL++KL + + GN+ S YKRLA+STLLLIPLFG+HY+VFA P
Sbjct: 305 SILINFILFINILRILMRKLRTQETRGNEVSHYKRLARSTLLLIPLFGIHYIVFAFSP-E 363
Query: 351 ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWR 391
+ + Q+ FEL LGSFQGLVVAVLYCFLN EVQ E+++KW+
Sbjct: 364 DAMEIQLFFELALGSFQGLVVAVLYCFLNGEVQLEVQKKWQ 404
>gi|58530851 growth hormone releasing hormone receptor isoform a
precursor [Homo sapiens]
Length = 423
Score = 338 bits (867), Expect = 6e-93
Identities = 166/376 (44%), Positives = 231/376 (61%), Gaps = 4/376 (1%)
Query: 21 IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS 80
+HPEC F +++E+E+ C + C WD + CW A GE VT+PCP FS
Sbjct: 24 MHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS 83
Query: 81 NFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMS 140
+F S++G + ++CT GWSE FP + AC + +++ VK IYT+G+S+S+++
Sbjct: 84 HFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVA 143
Query: 141 LATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWV 200
L IL R+LHC RNY+H LF +FIL+A +V +KD L+ S T HC S V
Sbjct: 144 LFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCS---FSTV 200
Query: 201 GCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPP-RRCFLAYLLIGWGLPTVCIGAW 259
CK+S+ + M NF WLL E +YL+ LL + P RR F +L GWGLP + G W
Sbjct: 201 LCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTW 260
Query: 260 TAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND 319
+ +L ED CWD +D S WW+I+ PI++S+ VNF LF++IIRIL++KL +
Sbjct: 261 VSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320
Query: 320 QSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFELCLGSFQGLVVAVLYCFLN 379
QSQY RL+KSTL LIPLFG+HY++F P + ++ EL LGSFQG +VA+LYCFLN
Sbjct: 321 QSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLN 380
Query: 380 SEVQCELKRKWRSRCP 395
EV+ E+ RKW P
Sbjct: 381 QEVRTEISRKWHGHDP 396
>gi|4506271 parathyroid hormone receptor 1 precursor [Homo sapiens]
Length = 593
Score = 285 bits (730), Expect = 4e-77
Identities = 156/393 (39%), Positives = 227/393 (57%), Gaps = 34/393 (8%)
Query: 50 KACSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETF 102
+ C WD+I CW GE V VPCP +F K G+ + C +G W + T+
Sbjct: 106 RPCLPEWDHILCWPLGAPGEVVAVPCPDYIYDFNHK-GHAYRRCDRNGSWELVPGHNRTW 164
Query: 103 PDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH 162
++ + + E + F L IYT+GYSVSL SL +IL FR+LHCTRNYIH
Sbjct: 165 ANYSECVKFLTNETREREVFDRL-GMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIH 223
Query: 163 LNLFLSFILRAISVLVKDDVLYSSS--------------GTLHCPDQPSS----WVGCKL 204
++LFLSF+LRA+S+ VKD VLYS + P P++ + GC++
Sbjct: 224 MHLFLSFMLRAVSIFVKDAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRV 283
Query: 205 SLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAAR 263
++ F Y + N++W+LVEGLYLH+L+ +A ++ + + GWGLP V + W + R
Sbjct: 284 AVTFFLYFLATNYYWILVEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVR 343
Query: 264 LYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND-QSQ 322
L +TGCWD + + W+I++PIL SI++NF+LFI+I+R+L KL + G D + Q
Sbjct: 344 ATLANTGCWDLSSGNKK-WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQ 402
Query: 323 YKRLAKSTLLLIPLFGVHYMVFAVFPISISS----KYQILFELCLGSFQGLVVAVLYCFL 378
Y++L KSTL+L+PLFGVHY+VF P + S + Q+ +E+ SFQG VA++YCF
Sbjct: 403 YRKLLKSTLVLMPLFGVHYIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFC 462
Query: 379 NSEVQCELKRKWRSRCPTPSASRDYRVCGSSFS 411
N EVQ E+K+ W R R SS+S
Sbjct: 463 NGEVQAEIKKSWSRWTLALDFKRKARSGSSSYS 495
>gi|4826954 parathyroid hormone 2 receptor precursor [Homo sapiens]
Length = 550
Score = 264 bits (674), Expect = 1e-70
Identities = 142/390 (36%), Positives = 227/390 (58%), Gaps = 32/390 (8%)
Query: 31 IQEEETKCAELLRSQTEKHKA-CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNI 89
+ + + +C + +Q ++ + C WD + CW VG+ VPCP +F K G
Sbjct: 41 VLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPCPPYIYDFNHK-GVA 99
Query: 90 SKNCTSDG-W------SETFPDFVDACGYSDPEDE-SKITFYILVKAIYTLGYSVSLMSL 141
++C +G W ++T+ ++ D + P+ K F+ + +YT+GYS+S SL
Sbjct: 100 FRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLYVMYTVGYSISFGSL 159
Query: 142 ATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSG-----TLHCPDQP 196
A +I+ FR+LHCTRNYIH++LF+SF+LRA S+ VKD V+++ G +L D P
Sbjct: 160 AVAILIIGYFRRLHCTRNYIHMHLFVSFMLRATSIFVKDRVVHAHIGVKELESLIMQDDP 219
Query: 197 -----------SSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAY 244
S ++GCK+++V Y + N++W+LVEGLYLH L+ VA + +
Sbjct: 220 QNSIEATSVDKSQYIGCKIAVVMFIYFLATNYYWILVEGLYLHNLIFVAFFSDTKYLWGF 279
Query: 245 LLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIR 304
+LIGWG P + AW AR L D CW+ + + W+ + PIL +I +NF+LF++ +R
Sbjct: 280 ILIGWGFPAAFVAAWAVARATLADARCWELSAGDIK-WIYQAPILAAIGLNFILFLNTVR 338
Query: 305 ILLQKLTSPDVGGND-QSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISS---KYQILFE 360
+L K+ + G+D + QY++LAKSTL+L+ +FGVHY+VF P S + + ++ E
Sbjct: 339 VLATKIWETNAVGHDTRKQYRKLAKSTLVLVLVFGVHYIVFVCLPHSFTGLGWEIRMHCE 398
Query: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
L SFQG V+++YC+ N EVQ E+K+ W
Sbjct: 399 LFFNSFQGFFVSIIYCYCNGEVQAEVKKMW 428
>gi|58530853 growth hormone releasing hormone receptor isoform b
precursor [Homo sapiens]
Length = 337
Score = 258 bits (659), Expect = 7e-69
Identities = 127/304 (41%), Positives = 181/304 (59%), Gaps = 4/304 (1%)
Query: 21 IHPECRFHLEIQEEETKCAELLRSQTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS 80
+HPEC F +++E+E+ C + C WD + CW A GE VT+PCP FS
Sbjct: 24 MHPECDFITQLREDESACLQAAEEMPNTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFS 83
Query: 81 NFYSKAGNISKNCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMS 140
+F S++G + ++CT GWSE FP + AC + +++ VK IYT+G+S+S+++
Sbjct: 84 HFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAEEESYFSTVKIIYTVGHSISIVA 143
Query: 141 LATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWV 200
L IL R+LHC RNY+H LF +FIL+A +V +KD L+ S T HC S V
Sbjct: 144 LFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHC---SFSTV 200
Query: 201 GCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLP-PRRCFLAYLLIGWGLPTVCIGAW 259
CK+S+ + M NF WLL E +YL+ LL + P RR F +L GWGLP + G W
Sbjct: 201 LCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTW 260
Query: 260 TAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGND 319
+ +L ED CWD +D S WW+I+ PI++S+ VNF LF++IIRIL++KL +
Sbjct: 261 VSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHT 320
Query: 320 QSQY 323
QSQY
Sbjct: 321 QSQY 324
>gi|4758438 glucagon-like peptide 2 receptor precursor [Homo
sapiens]
Length = 553
Score = 258 bits (658), Expect = 1e-68
Identities = 148/386 (38%), Positives = 216/386 (55%), Gaps = 36/386 (9%)
Query: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKA-GNISKNCTSDGWSETFPDFVDAC- 109
C+G +D CW ++ G V+VPCP + ++ G ++C + G +T + D
Sbjct: 96 CNGTFDQYVCWPHSSPGN-VSVPCPSYLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQ 154
Query: 110 -------GYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH 162
+S ++ + ++ +YT+GYS SL+SL +L RKLHCTRNYIH
Sbjct: 155 DDSECSENHSFKQNVDRYALLSTLQLMYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIH 214
Query: 163 LNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVG--------CKLSLVFLQYCIM 214
+NLF SFILR ++VLVKD V Y+S PD + W+ C+ V L Y +
Sbjct: 215 MNLFASFILRTLAVLVKDVVFYNSYSKR--PDNENGWMSYLSEMSTSCRSVQVLLHYFVG 272
Query: 215 ANFFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCWD 273
AN+ WLLVEGLYLHTLL +LP RR + YLL+GW P + + W AR +LE+TGCW
Sbjct: 273 ANYLWLLVEGLYLHTLLEPTVLPERRLWPRYLLLGWAFPVLFVVPWGFARAHLENTGCWT 332
Query: 274 TNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYK-RLAKSTLL 332
TN + WW+IR P+++ + VNF +F+ I+++L+ KL + + D YK RLAKSTL+
Sbjct: 333 TNGNKKIWWIIRGPMMLCVTVNFFIFLKILKLLISKLKAHQMCFRD---YKYRLAKSTLV 389
Query: 333 LIPLFGVHYMVFAVFP----ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKR 388
LIPL GVH ++F+ + ++ +L L SF G +VA+ Y F N EV+ EL++
Sbjct: 390 LIPLLGVHEILFSFITDDQVEGFAKLIRLFIQLTLSSFHGFLVALQYGFANGEVKAELRK 449
Query: 389 KW-------RSRCPTPSASRDYRVCG 407
W S C +D+R G
Sbjct: 450 YWVRFLLARHSGCRACVLGKDFRFLG 475
>gi|4503999 gastric inhibitory polypeptide receptor [Homo sapiens]
Length = 466
Score = 250 bits (639), Expect = 2e-66
Identities = 148/372 (39%), Positives = 210/372 (56%), Gaps = 27/372 (7%)
Query: 37 KCAELLRS-QTEKHKACSGVWDNITCWRPANVGETVTVPCPKVFS-NFYSKAGNISKNCT 94
+C E L + + AC+G +D CW A T CP + + AG + + C
Sbjct: 45 ECQETLAAAEPPSGLACNGSFDMYVCWDYAAPNATARASCPWYLPWHHHVAAGFVLRQCG 104
Query: 95 SDGWSETFPDFVDACGYSDPEDESKITFYILV----KAIYTLGYSVSLMSLATGSIILCL 150
SDG + D +PE L+ + +YT+GYS+SL +L +IL L
Sbjct: 105 SDGQWGLWRDHTQC---ENPEKNEAFLDQRLILERLQVMYTVGYSLSLATLLLALLILSL 161
Query: 151 FRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL-----YSSSGTLHCPDQPSSWVGCKLS 205
FR+LHCTRNYIH+NLF SF+LRA ++L +D +L Y L +Q + C+ +
Sbjct: 162 FRRLHCTRNYIHINLFTSFMLRAAAILSRDRLLPRPGPYLGDQALALWNQ--ALAACRTA 219
Query: 206 LVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC-FLAYLLIGWGLPTVCIGAWTAARL 264
+ QYC+ AN+ WLLVEG+YLH+LLV + F YLL+GWG P + + W R
Sbjct: 220 QIVTQYCVGANYTWLLVEGVYLHSLLVLVGGSEEGHFRYYLLLGWGAPALFVIPWVIVRY 279
Query: 265 YLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYK 324
E+T CW+ N+ WW+IR PIL++I++NF++FI I+ ILL KL + + D
Sbjct: 280 LYENTQCWERNEVKAIWWIIRTPILMTILINFLIFIRILGILLSKLRTRQMRCRDYR--L 337
Query: 325 RLAKSTLLLIPLFGVHYMVFAVFPISISSKYQIL------FELCLGSFQGLVVAVLYCFL 378
RLA+STL L+PL GVH +VFA P++ L FE+ L SFQG +V+VLYCF+
Sbjct: 338 RLARSTLTLVPLLGVHEVVFA--PVTEEQARGALRFAKLGFEIFLSSFQGFLVSVLYCFI 395
Query: 379 NSEVQCELKRKW 390
N EVQ E++R W
Sbjct: 396 NKEVQSEIRRGW 407
>gi|4503947 glucagon receptor [Homo sapiens]
Length = 477
Score = 247 bits (631), Expect = 1e-65
Identities = 146/364 (40%), Positives = 208/364 (57%), Gaps = 31/364 (8%)
Query: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGN--ISKNCTSDG----------WS 99
C+ +D +CW T + CP + ++ K + + K C DG W
Sbjct: 58 CNRTFDKYSCWPDTPANTTANISCPW-YLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWR 116
Query: 100 ETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRN 159
+ +D ++ +K+ Y + +YT+GYS+SL +L IL KLHCTRN
Sbjct: 117 DASQCQMDGEEIEVQKEVAKM--YSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRN 174
Query: 160 YIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPD-QPSSWV------GCKLSLVFLQYC 212
IH NLF SF+L+A SVLV D +L + D S+W+ GC+++ VF+QY
Sbjct: 175 AIHANLFASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYG 234
Query: 213 IMANFFWLLVEGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGC 271
I+AN+ WLLVEGLYLH LL +A LP R F YL IGWG P + + W + E+ C
Sbjct: 235 IVANYCWLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQC 294
Query: 272 WDTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYK-RLAKST 330
W +ND+ WW++R P+ ++I++NF +F+ I+++L+ KL + + D YK RLAKST
Sbjct: 295 WTSNDNMGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTD---YKFRLAKST 351
Query: 331 LLLIPLFGVHYMVFAVFPISISS----KYQILFELCLGSFQGLVVAVLYCFLNSEVQCEL 386
L LIPL GVH +VFA + ++ F+L L SFQGL+VAVLYCFLN EVQ EL
Sbjct: 352 LTLIPLLGVHEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSEL 411
Query: 387 KRKW 390
+R+W
Sbjct: 412 RRRW 415
>gi|166795283 glucagon-like peptide 1 receptor [Homo sapiens]
Length = 463
Score = 244 bits (623), Expect = 1e-64
Identities = 145/363 (39%), Positives = 205/363 (56%), Gaps = 31/363 (8%)
Query: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYS-KAGNISKNCTSDG-----------WS 99
C+ +D CW G V V CP S G++ + CT++G W
Sbjct: 62 CNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWR 121
Query: 100 ETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRN 159
+ G +E + YI IYT+GY++S +L S IL FR LHCTRN
Sbjct: 122 DLSECEESKRGERSSPEEQLLFLYI----IYTVGYALSFSALVIASAILLGFRHLHCTRN 177
Query: 160 YIHLNLFLSFILRAISVLVKDDVL---YSSSGTLHCPDQPSSW---VGCKLSLVFLQYCI 213
YIHLNLF SFILRA+SV +KD L YS++ H D S+ + C+L + +QYC+
Sbjct: 178 YIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCV 237
Query: 214 MANFFWLLVEGLYLHTLLV-AMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCW 272
AN++WLLVEG+YL+TLL ++L + F Y+ IGWG+P + + W + ED GCW
Sbjct: 238 AANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCW 297
Query: 273 DTNDHSVPWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLL 332
N + W +IR+PIL +I VNF++F+ +I I++ KL + + D RLAKSTL
Sbjct: 298 TRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIK--CRLAKSTLT 355
Query: 333 LIPLFGVHYMVFAVFPISISSKYQILF-----ELCLGSFQGLVVAVLYCFLNSEVQCELK 387
LIPL G H ++FA F + ++ + F EL SFQGL+VA+LYCF+N+EVQ E +
Sbjct: 356 LIPLLGTHEVIFA-FVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFR 414
Query: 388 RKW 390
+ W
Sbjct: 415 KSW 417
>gi|19923245 corticotropin releasing hormone receptor 1 isoform 2
[Homo sapiens]
Length = 415
Score = 182 bits (463), Expect = 4e-46
Identities = 115/364 (31%), Positives = 185/364 (50%), Gaps = 18/364 (4%)
Query: 34 EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91
++ C L + C+ D I TCW + G+ V PCP F Y+ N +
Sbjct: 26 QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85
Query: 92 NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151
C ++G ++ + + E +SK+ +++ V Y LG+ +SL++L ++
Sbjct: 86 ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144
Query: 152 RKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVG-CKLSLVFLQ 210
R + C RN IH NL +FILR + V + P+ S VG C+L
Sbjct: 145 RSIRCLRNIIHWNLISAFILRNATWFVVQLTM--------SPEVHQSNVGWCRLVTAAYN 196
Query: 211 YCIMANFFWLLVEGLYLHTLLVAMLPPRRCFL-AYLLIGWGLPTVCIGAWTAARLYLEDT 269
Y + NFFW+ EG YLHT +V R ++ IGWG+P I AW +LY ++
Sbjct: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
Query: 270 GCWDTNDHSVPW-WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAK 328
CW V ++ + P+++ +++NF+ +I+RIL+ KL + ++ QY++ K
Sbjct: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVK 314
Query: 329 STLLLIPLFGVHYMVFAVFP--ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCEL 386
+TL+L+PL G+ YM+F V P +S I F L SFQG V+V YCFLNSEV+ +
Sbjct: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAI 374
Query: 387 KRKW 390
+++W
Sbjct: 375 RKRW 378
>gi|32307159 corticotropin releasing hormone receptor 2 [Homo
sapiens]
Length = 411
Score = 180 bits (456), Expect = 3e-45
Identities = 109/347 (31%), Positives = 173/347 (49%), Gaps = 20/347 (5%)
Query: 52 CSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISKNCTSDGWSETFPDFVDAC 109
C+ D I TCW + G V PCP+ F+ Y+ N + C +G + ++
Sbjct: 40 CNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCE 99
Query: 110 GYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSF 169
D + Y + + LG+ VS+ +L ++ R + C RN IH NL +F
Sbjct: 100 PILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTF 159
Query: 170 ILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHT 229
ILR +V++ + S+ V C+ Y ++ NFFW+ VEG YLHT
Sbjct: 160 ILR--------NVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHT 211
Query: 230 LLVAMLPP---RRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCW-DTNDHSVPWWVIR 285
+V R+C +L IGW +P I AW +LY E+ CW + ++ +
Sbjct: 212 AIVMTYSTERLRKCL--FLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQ 269
Query: 286 IPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFA 345
PI++ +++NFV +I+RIL+ KL + ++ QY++ K+TL+L+PL G+ YM+F
Sbjct: 270 GPIILVLLINFVFLFNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFF 327
Query: 346 VFP--ISISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
V P +S I F L SFQG V+V YCF N EV+ ++++W
Sbjct: 328 VNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRW 374
>gi|223717971 corticotropin releasing hormone receptor 1 isoform 1
[Homo sapiens]
Length = 444
Score = 167 bits (423), Expect = 2e-41
Identities = 115/393 (29%), Positives = 185/393 (47%), Gaps = 47/393 (11%)
Query: 34 EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91
++ C L + C+ D I TCW + G+ V PCP F Y+ N +
Sbjct: 26 QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85
Query: 92 NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151
C ++G ++ + + E +SK+ +++ V Y LG+ +SL++L ++
Sbjct: 86 ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144
Query: 152 R-----------------------------KLHCTRNYIHLNLFLSFILRAISVLVKDDV 182
R + C RN IH NL +FILR + V
Sbjct: 145 RPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLRNIIHWNLISAFILRNATWFVVQLT 204
Query: 183 LYSSSGTLHCPDQPSSWVG-CKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCF 241
+ P+ S VG C+L Y + NFFW+ EG YLHT +V R
Sbjct: 205 M--------SPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLR 256
Query: 242 L-AYLLIGWGLPTVCIGAWTAARLYLEDTGCWDTNDHSVPW-WVIRIPILISIIVNFVLF 299
++ IGWG+P I AW +LY ++ CW V ++ + P+++ +++NF+
Sbjct: 257 KWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFL 316
Query: 300 ISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP--ISISSKYQI 357
+I+RIL+ KL + ++ QY++ K+TL+L+PL G+ YM+F V P +S I
Sbjct: 317 FNIVRILMTKLRASTT--SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFI 374
Query: 358 LFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
F L SFQG V+V YCFLNSEV+ ++++W
Sbjct: 375 YFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRW 407
>gi|223717978 corticotropin releasing hormone receptor 1 isoform 3
[Homo sapiens]
Length = 375
Score = 166 bits (421), Expect = 3e-41
Identities = 105/316 (33%), Positives = 167/316 (52%), Gaps = 20/316 (6%)
Query: 84 SKAGNISKN----CTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLM 139
S A NIS N C ++G ++ + + E +SK+ +++ V Y LG+ +SL+
Sbjct: 34 SLASNISDNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLV 92
Query: 140 SLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSW 199
+L ++ R + C RN IH NL +FILR + V + P+ S
Sbjct: 93 ALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTM--------SPEVHQSN 144
Query: 200 VG-CKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFL-AYLLIGWGLPTVCIG 257
VG C+L Y + NFFW+ EG YLHT +V R ++ IGWG+P I
Sbjct: 145 VGWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIV 204
Query: 258 AWTAARLYLEDTGCWDTNDHSVPW-WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVG 316
AW +LY ++ CW V ++ + P+++ +++NF+ +I+RIL+ KL +
Sbjct: 205 AWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT- 263
Query: 317 GNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFP--ISISSKYQILFELCLGSFQGLVVAVL 374
++ QY++ K+TL+L+PL G+ YM+F V P +S I F L SFQG V+V
Sbjct: 264 -SETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVSVF 322
Query: 375 YCFLNSEVQCELKRKW 390
YCFLNSEV+ ++++W
Sbjct: 323 YCFLNSEVRSAIRKRW 338
>gi|4502547 calcitonin receptor [Homo sapiens]
Length = 474
Score = 160 bits (406), Expect = 2e-39
Identities = 105/352 (29%), Positives = 176/352 (50%), Gaps = 30/352 (8%)
Query: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETFPD 104
C+ WD CW G CP F +F + ++K C G W + T+ +
Sbjct: 72 CNRTWDGWLCWDDTPAGVLSYQFCPDYFPDF-DPSEKVTKYCDEKGVWFKHPENNRTWSN 130
Query: 105 FVDACGYSDPED--ESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIH 162
+ C PE + + +Y+ + +G+S+S+ +L I FR L C R +H
Sbjct: 131 YT-MCNAFTPEKLKNAYVLYYLAI-----VGHSLSIFTLVISLGIFVFFRSLGCQRVTLH 184
Query: 163 LNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLV 222
N+FL++IL ++ +++ V +G L D V CK+ F QY + N+FW+L
Sbjct: 185 KNMFLTYILNSMIIIIHL-VEVVPNGELVRRDP----VSCKILHFFHQYMMACNYFWMLC 239
Query: 223 EGLYLHTLL-VAMLPPRRCFLAYLLIGWGLPTVCIGAWTAARLYLEDTGCW-DTNDHSVP 280
EG+YLHTL+ VA+ ++ Y L+GWG P V R + CW H +
Sbjct: 240 EGIYLHTLIVVAVFTEKQRLRWYYLLGWGFPLVPTTIHAITRAVYFNDNCWLSVETHLL- 298
Query: 281 WWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVH 340
++I P++ +++VNF ++I+R+L+ K+ + + Y + K+T++L+PL G+
Sbjct: 299 -YIIHGPVMAALVVNFFFLLNIVRVLVTKMR--ETHEAESHMYLKAVKATMILVPLLGIQ 355
Query: 341 YMVFAVFPIS--ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
++VF P + + Y + L FQG VA +YCF N+EVQ +KR+W
Sbjct: 356 FVVFPWRPSNKMLGKIYDYVMH-SLIHFQGFFVATIYCFCNNEVQTTVKRQW 406
>gi|5031621 calcitonin receptor-like [Homo sapiens]
Length = 461
Score = 155 bits (392), Expect = 7e-38
Identities = 99/350 (28%), Positives = 174/350 (49%), Gaps = 26/350 (7%)
Query: 52 CSGVWDNITCWRPANVGETVTVPCPKVFSNFYSKAGNISKNCTSDG-W------SETFPD 104
C+ WD CW G CP F +F + ++K C DG W + T+ +
Sbjct: 65 CNRTWDGWLCWNDVAAGTESMQLCPDYFQDF-DPSEKVTKICDQDGNWFRHPASNRTWTN 123
Query: 105 FVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLN 164
+ + + ++ + + L +G+ +S+ SL I F+ L C R +H N
Sbjct: 124 YTQCNVNTHEKVKTALNLFYLT----IIGHGLSIASLLISLGIFFYFKSLSCQRITLHKN 179
Query: 165 LFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEG 224
LF SF+ ++ ++ + ++ + ++ V CK+S Y + N+FW+L EG
Sbjct: 180 LFFSFVCNSVVTIIHLTAVANNQALV-----ATNPVSCKVSQFIHLYLMGCNYFWMLCEG 234
Query: 225 LYLHTLL-VAMLPPRRCFLAYLLIGWGLPTV--CIGAWTAARLYLEDTGCWDTNDHSVPW 281
+YLHTL+ VA+ ++ + Y +GWG P + CI A A LY D CW ++D +
Sbjct: 235 IYLHTLIVVAVFAEKQHLMWYYFLGWGFPLIPACIHA-IARSLYYND-NCWISSDTHL-L 291
Query: 282 WVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHY 341
++I PI +++VN ++I+R+L+ KL + + Y + ++TL+L+PL G+ +
Sbjct: 292 YIIHGPICAALLVNLFFLLNIVRVLITKLKVTHQA--ESNLYMKAVRATLILVPLLGIEF 349
Query: 342 MVFAVFPI-SISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
++ P I+ + L FQGL+V+ ++CF N EVQ L+R W
Sbjct: 350 VLIPWRPEGKIAEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNW 399
>gi|223717985 corticotropin releasing hormone receptor 1 isoform 4
[Homo sapiens]
Length = 401
Score = 153 bits (386), Expect = 3e-37
Identities = 103/341 (30%), Positives = 167/341 (48%), Gaps = 18/341 (5%)
Query: 34 EETKCAELLRSQTEKHKACSGVWDNI-TCWRPANVGETVTVPCPKVFSNF-YSKAGNISK 91
++ C L + C+ D I TCW + G+ V PCP F Y+ N +
Sbjct: 26 QDQHCESLSLASNISGLQCNASVDLIGTCWPRSPAGQLVVRPCPAFFYGVRYNTTNNGYR 85
Query: 92 NCTSDGWSETFPDFVDACGYSDPEDESKITFYILVKAIYTLGYSVSLMSLATGSIILCLF 151
C ++G ++ + + E +SK+ +++ V Y LG+ +SL++L ++
Sbjct: 86 ECLANGSWAARVNYSECQEILNEEKKSKVHYHVAVIINY-LGHCISLVALLVAFVLFLRL 144
Query: 152 RKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSGTLHCPDQPSSWVG-CKLSLVFLQ 210
R + C RN IH NL +FILR + V + P+ S VG C+L
Sbjct: 145 RSIRCLRNIIHWNLISAFILRNATWFVVQLTM--------SPEVHQSNVGWCRLVTAAYN 196
Query: 211 YCIMANFFWLLVEGLYLHTLLVAMLPPRRC-FLAYLLIGWGLPTVCIGAWTAARLYLEDT 269
Y + NFFW+ EG YLHT +V R ++ IGWG+P I AW +LY ++
Sbjct: 197 YFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNE 256
Query: 270 GCWDTNDHSV-PWWVIRIPILISIIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAK 328
CW V ++ + P+++ +++NF+ +I+RIL+ KL + ++ QY++ K
Sbjct: 257 KCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRASTT--SETIQYRKAVK 314
Query: 329 STLLLIPLFGVHYMVFAVFP--ISISSKYQILFELCLGSFQ 367
+TL+L+PL G+ YM+F V P +S I F L SFQ
Sbjct: 315 ATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQ 355
>gi|45433552 G protein-coupled receptor 133 [Homo sapiens]
Length = 874
Score = 95.1 bits (235), Expect = 1e-19
Identities = 75/285 (26%), Positives = 136/285 (47%), Gaps = 23/285 (8%)
Query: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRN---YIHLNLFLSFILRAISVLVKD 180
+ + +I +G S+S++ L + + + RN +IH NL + ++ + +L+
Sbjct: 564 VALSSISYVGCSLSVLCLVATLVTFAVLSSVSTIRNQRYHIHANLSFAVLVAQVLLLISF 623
Query: 181 DVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRC 240
+ +P + C++ V L Y ++ F W+LVEGL+L+++++ +
Sbjct: 624 RL------------EPGT-TPCQVMAVLLHYFFLSAFAWMLVEGLHLYSMVIKVFGSEDS 670
Query: 241 FLAYLL-IGWGLP-TVCIGAWT-AARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFV 297
Y +GWG P +CI + + A Y CW + S W P L I+VN
Sbjct: 671 KHRYYYGMGWGFPLLICIISLSFAMDSYGTSNNCW-LSLASGAIWAFVAPALFVIVVNIG 729
Query: 298 LFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPIS-ISSKYQ 356
+ I++ R++ Q D S +K AK+ +L+P+ G + VF V ++ + +Q
Sbjct: 730 ILIAVTRVISQISADNYKIHGDPSAFKLTAKAVAVLLPILGTSW-VFGVLAVNGCAVVFQ 788
Query: 357 ILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASR 401
+F L S QGL + + +C LNSEV+ K K + T S++R
Sbjct: 789 YMF-ATLNSLQGLFIFLFHCLLNSEVRAAFKHKTKVWSLTSSSAR 832
>gi|163792198 latrophilin 3 precursor [Homo sapiens]
Length = 1469
Score = 79.7 bits (195), Expect = 5e-15
Identities = 77/318 (24%), Positives = 135/318 (42%), Gaps = 32/318 (10%)
Query: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL 183
+L+ I +G +SL+ L C FR L RN IH NL +S + + L+
Sbjct: 875 LLLDVITWVGILLSLVCLLICIFTFCFFRGLQSDRNTIHKNLCISLFVAELLFLI----- 929
Query: 184 YSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLA 243
++ DQP + C + L + +A F W+ +EG+ L+ +LV +
Sbjct: 930 -----GINRTDQP---IACAVFAALLHFFFLAAFTWMFLEGVQLYIMLVEVFESEHSRRK 981
Query: 244 YL-LIGWGLPT--VCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI 300
Y L+G+G+P V + A R Y D CW D W I P + I++N V+F+
Sbjct: 982 YFYLVGYGMPALIVAVSAAVDYRSYGTDKVCWLRLDTYFIWSFIG-PATLIIMLN-VIFL 1039
Query: 301 SIIRILL---QKLTSPDVGGNDQSQY-------KRLAKSTLLLIPLFGVHYMVFAVFPIS 350
I + + P+ G D Y K + L+ L G+ + F + I+
Sbjct: 1040 GIALYKMFHHTAILKPESGCLDNINYEDNRPFIKSWVIGAIALLCLLGLTW-AFGLMYIN 1098
Query: 351 ISSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKWRSRCPTPSASRDYRVCGSSF 410
S+ S QG+ + + +C L +V+ E + R+ C + ++ G +
Sbjct: 1099 ESTVIMAYLFTIFNSLQGMFIFIFHCVLQKKVRKEYGKCLRTHCCSGKSTESSIGSGKT- 1157
Query: 411 SRNGSEGALQFHRGSRAQ 428
+GS ++ GS+++
Sbjct: 1158 --SGSRTPGRYSTGSQSR 1173
>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
Length = 1474
Score = 77.0 bits (188), Expect = 3e-14
Identities = 66/268 (24%), Positives = 110/268 (41%), Gaps = 18/268 (6%)
Query: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL 183
+L+ I +G +SL+ LA C R L RN IH NL ++ L + LV
Sbjct: 858 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVG---- 913
Query: 184 YSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLA 243
D+ + C + L Y +A F WL +EG++L+ LLV +
Sbjct: 914 ---------IDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTK 964
Query: 244 YLLI-GWGLPTVCIGAWTAA--RLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI 300
Y + G+ P + +G A R Y + CW D+ W I P+ I+VN V +
Sbjct: 965 YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG-PVSFVIVVNLVFLM 1023
Query: 301 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE 360
+ +++ + + K A + L+ L G+ + F + I+ S
Sbjct: 1024 VTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTW-AFGLLFINKESVVMAYLF 1082
Query: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKR 388
+FQG+ + V +C L +V E +
Sbjct: 1083 TTFNAFQGVFIFVFHCALQKKVHKEYSK 1110
>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
Length = 1469
Score = 77.0 bits (188), Expect = 3e-14
Identities = 66/268 (24%), Positives = 110/268 (41%), Gaps = 18/268 (6%)
Query: 124 ILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVL 183
+L+ I +G +SL+ LA C R L RN IH NL ++ L + LV
Sbjct: 853 LLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVG---- 908
Query: 184 YSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLA 243
D+ + C + L Y +A F WL +EG++L+ LLV +
Sbjct: 909 ---------IDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTK 959
Query: 244 YLLI-GWGLPTVCIGAWTAA--RLYLEDTGCWDTNDHSVPWWVIRIPILISIIVNFVLFI 300
Y + G+ P + +G A R Y + CW D+ W I P+ I+VN V +
Sbjct: 960 YYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIG-PVSFVIVVNLVFLM 1018
Query: 301 SIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISISSKYQILFE 360
+ +++ + + K A + L+ L G+ + F + I+ S
Sbjct: 1019 VTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTW-AFGLLFINKESVVMAYLF 1077
Query: 361 LCLGSFQGLVVAVLYCFLNSEVQCELKR 388
+FQG+ + V +C L +V E +
Sbjct: 1078 TTFNAFQGVFIFVFHCALQKKVHKEYSK 1105
>gi|68508955 CD97 antigen isoform 3 precursor [Homo sapiens]
Length = 786
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/274 (26%), Positives = 121/274 (44%), Gaps = 35/274 (12%)
Query: 129 IYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSG 188
I +G ++SL L + L R + +R IHL+L + + + L + G
Sbjct: 501 ITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVG 560
Query: 189 TLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYL-LI 247
+ C+L L YC +A F W+ +EGL L+ L+V + + +L LI
Sbjct: 561 -----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLI 609
Query: 248 GWGLPTVCIGAWTAARLYLEDTG----CWDTNDHSVPWWVIRIPILISIIVNFVLFISII 303
G+G+P + +G +A +Y + G CW + W + P+ I+ N V+F++ +
Sbjct: 610 GYGVPLLIVG--VSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIILCNAVIFVTTV 666
Query: 304 RILLQKLT--SPDVGGNDQSQYKRLAKSTLLLIPLFGVHYM-----VFAVFPISISSKYQ 356
L QK + +PD+ K+L K+ L I ++ VF +F S
Sbjct: 667 WKLTQKFSEINPDM--------KKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVL 718
Query: 357 ILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
L QG + +L+C LN +V+ E RKW
Sbjct: 719 TYVFTILNCLQGAFLYLLHCLLNKKVR-EEYRKW 751
>gi|17978489 CD97 antigen isoform 2 precursor [Homo sapiens]
Length = 742
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/274 (26%), Positives = 121/274 (44%), Gaps = 35/274 (12%)
Query: 129 IYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSG 188
I +G ++SL L + L R + +R IHL+L + + + L + G
Sbjct: 457 ITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVG 516
Query: 189 TLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYL-LI 247
+ C+L L YC +A F W+ +EGL L+ L+V + + +L LI
Sbjct: 517 -----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLI 565
Query: 248 GWGLPTVCIGAWTAARLYLEDTG----CWDTNDHSVPWWVIRIPILISIIVNFVLFISII 303
G+G+P + +G +A +Y + G CW + W + P+ I+ N V+F++ +
Sbjct: 566 GYGVPLLIVG--VSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIILCNAVIFVTTV 622
Query: 304 RILLQKLT--SPDVGGNDQSQYKRLAKSTLLLIPLFGVHYM-----VFAVFPISISSKYQ 356
L QK + +PD+ K+L K+ L I ++ VF +F S
Sbjct: 623 WKLTQKFSEINPDM--------KKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVL 674
Query: 357 ILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
L QG + +L+C LN +V+ E RKW
Sbjct: 675 TYVFTILNCLQGAFLYLLHCLLNKKVR-EEYRKW 707
>gi|17978491 CD97 antigen isoform 1 precursor [Homo sapiens]
Length = 835
Score = 75.1 bits (183), Expect = 1e-13
Identities = 72/274 (26%), Positives = 121/274 (44%), Gaps = 35/274 (12%)
Query: 129 IYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVKDDVLYSSSG 188
I +G ++SL L + L R + +R IHL+L + + + L + G
Sbjct: 550 ITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVG 609
Query: 189 TLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYLHTLLVAMLPPRRCFLAYL-LI 247
+ C+L L YC +A F W+ +EGL L+ L+V + + +L LI
Sbjct: 610 -----------LRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLI 658
Query: 248 GWGLPTVCIGAWTAARLYLEDTG----CWDTNDHSVPWWVIRIPILISIIVNFVLFISII 303
G+G+P + +G +A +Y + G CW + W + P+ I+ N V+F++ +
Sbjct: 659 GYGVPLLIVG--VSAAIYSKGYGRPRYCWLDFEQGFLWSFLG-PVTFIILCNAVIFVTTV 715
Query: 304 RILLQKLT--SPDVGGNDQSQYKRLAKSTLLLIPLFGVHYM-----VFAVFPISISSKYQ 356
L QK + +PD+ K+L K+ L I ++ VF +F S
Sbjct: 716 WKLTQKFSEINPDM--------KKLKKARALTITAIAQLFLLGCTWVFGLFIFDDRSLVL 767
Query: 357 ILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
L QG + +L+C LN +V+ E RKW
Sbjct: 768 TYVFTILNCLQGAFLYLLHCLLNKKVR-EEYRKW 800
>gi|23397681 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform a [Homo sapiens]
Length = 823
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/339 (23%), Positives = 136/339 (40%), Gaps = 42/339 (12%)
Query: 73 VPCPKVFSNFYSKAGN-----ISKNCTSDGWSET--------FPDFVDACGYSDPEDESK 119
+P KV F+ N + C++ G +T F + D ++E
Sbjct: 475 IPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP 534
Query: 120 ITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVK 179
+ + I +G SVSL+ L ++ L + + T +HL L L L + LV
Sbjct: 535 V-----LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLV- 588
Query: 180 DDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYL----HTLLVAML 235
DQ V C + L Y +A W+L+E LYL L V
Sbjct: 589 ------------AIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 636
Query: 236 PPRRCFLAYLL--IGWGLP--TVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILIS 291
F+ L+ +G+G+P TV I A + LY + CW + W + P+
Sbjct: 637 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG-PVCAI 695
Query: 292 IIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISI 351
VN VLF+ + IL +L+S + + + LA + + G + + + +
Sbjct: 696 FSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCL-GILQVGP 754
Query: 352 SSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
+++ + S QG+ + ++YC L+ +V+ E KW
Sbjct: 755 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVR-EQYGKW 792
>gi|23397693 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform g [Homo sapiens]
Length = 719
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/339 (23%), Positives = 136/339 (40%), Gaps = 42/339 (12%)
Query: 73 VPCPKVFSNFYSKAGN-----ISKNCTSDGWSET--------FPDFVDACGYSDPEDESK 119
+P KV F+ N + C++ G +T F + D ++E
Sbjct: 371 IPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP 430
Query: 120 ITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVK 179
+ + I +G SVSL+ L ++ L + + T +HL L L L + LV
Sbjct: 431 V-----LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLV- 484
Query: 180 DDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYL----HTLLVAML 235
DQ V C + L Y +A W+L+E LYL L V
Sbjct: 485 ------------AIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 532
Query: 236 PPRRCFLAYLL--IGWGLP--TVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILIS 291
F+ L+ +G+G+P TV I A + LY + CW + W + P+
Sbjct: 533 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG-PVCAI 591
Query: 292 IIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISI 351
VN VLF+ + IL +L+S + + + LA + + G + + + +
Sbjct: 592 FSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCL-GILQVGP 650
Query: 352 SSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
+++ + S QG+ + ++YC L+ +V+ E KW
Sbjct: 651 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVR-EQYGKW 688
>gi|23397691 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform f [Homo sapiens]
Length = 763
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/339 (23%), Positives = 136/339 (40%), Gaps = 42/339 (12%)
Query: 73 VPCPKVFSNFYSKAGN-----ISKNCTSDGWSET--------FPDFVDACGYSDPEDESK 119
+P KV F+ N + C++ G +T F + D ++E
Sbjct: 415 IPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP 474
Query: 120 ITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVK 179
+ + I +G SVSL+ L ++ L + + T +HL L L L + LV
Sbjct: 475 V-----LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLV- 528
Query: 180 DDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYL----HTLLVAML 235
DQ V C + L Y +A W+L+E LYL L V
Sbjct: 529 ------------AIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 576
Query: 236 PPRRCFLAYLL--IGWGLP--TVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILIS 291
F+ L+ +G+G+P TV I A + LY + CW + W + P+
Sbjct: 577 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG-PVCAI 635
Query: 292 IIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISI 351
VN VLF+ + IL +L+S + + + LA + + G + + + +
Sbjct: 636 FSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCL-GILQVGP 694
Query: 352 SSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
+++ + S QG+ + ++YC L+ +V+ E KW
Sbjct: 695 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVR-EQYGKW 732
>gi|23397689 egf-like module containing, mucin-like, hormone
receptor-like sequence 2 isoform e [Homo sapiens]
Length = 812
Score = 74.3 bits (181), Expect = 2e-13
Identities = 79/339 (23%), Positives = 136/339 (40%), Gaps = 42/339 (12%)
Query: 73 VPCPKVFSNFYSKAGN-----ISKNCTSDGWSET--------FPDFVDACGYSDPEDESK 119
+P KV F+ N + C++ G +T F + D ++E
Sbjct: 464 IPRQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEEDP 523
Query: 120 ITFYILVKAIYTLGYSVSLMSLATGSIILCLFRKLHCTRNYIHLNLFLSFILRAISVLVK 179
+ + I +G SVSL+ L ++ L + + T +HL L L L + LV
Sbjct: 524 V-----LTVITYMGLSVSLLCLLLAALTFLLCKAIQNTSTSLHLQLSLCLFLAHLLFLV- 577
Query: 180 DDVLYSSSGTLHCPDQPSSWVGCKLSLVFLQYCIMANFFWLLVEGLYL----HTLLVAML 235
DQ V C + L Y +A W+L+E LYL L V
Sbjct: 578 ------------AIDQTGHKVLCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNY 625
Query: 236 PPRRCFLAYLL--IGWGLP--TVCIGAWTAARLYLEDTGCWDTNDHSVPWWVIRIPILIS 291
F+ L+ +G+G+P TV I A + LY + CW + W + P+
Sbjct: 626 SSINRFMKKLMFPVGYGVPAVTVAISAASRPHLYGTPSRCWLQPEKGFIWGFLG-PVCAI 684
Query: 292 IIVNFVLFISIIRILLQKLTSPDVGGNDQSQYKRLAKSTLLLIPLFGVHYMVFAVFPISI 351
VN VLF+ + IL +L+S + + + LA + + G + + + +
Sbjct: 685 FSVNLVLFLVTLWILKNRLSSLNSEVSTLRNTRMLAFKATAQLFILGCTWCL-GILQVGP 743
Query: 352 SSKYQILFELCLGSFQGLVVAVLYCFLNSEVQCELKRKW 390
+++ + S QG+ + ++YC L+ +V+ E KW
Sbjct: 744 AARVMAYLFTIINSLQGVFIFLVYCLLSQQVR-EQYGKW 781
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.140 0.456
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,096,626
Number of Sequences: 37866
Number of extensions: 748253
Number of successful extensions: 2541
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 2303
Number of HSP's gapped (non-prelim): 112
length of query: 438
length of database: 18,247,518
effective HSP length: 105
effective length of query: 333
effective length of database: 14,271,588
effective search space: 4752438804
effective search space used: 4752438804
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.