Search of human proteins with 21314728

Search of human proteins with 21314728

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21314728 centrosomal protein 76kDa [Homo sapiens]
         (659 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21314728 centrosomal protein 76kDa [Homo sapiens]                 1350   0.0  
gi|229577352 coiled-coil and C2 domain containing 2B isoform 1 [...    78   2e-14
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [...    66   9e-11
gi|197209817 coiled-coil and C2 domain containing 2A isoform b [...    65   2e-10
gi|109452583 coiled-coil and C2 domain containing 2B isoform 2 [...    57   7e-08
gi|223941912 coiled-coil domain containing 135 [Homo sapiens]          32   1.4  
gi|110611228 utrophin [Homo sapiens]                                   32   1.9  
gi|42734401 testis-specific serine kinase 4 [Homo sapiens]             32   1.9  
gi|221316699 maltase-glucoamylase [Homo sapiens]                       31   4.1  
gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]        31   4.1  
gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]       31   4.1  

>gi|21314728 centrosomal protein 76kDa [Homo sapiens]
          Length = 659

 Score = 1350 bits (3493), Expect = 0.0
 Identities = 659/659 (100%), Positives = 659/659 (100%)

Query: 1   MSLPPEKASELKQLIHQQLSKMDVHGRIREILAETIREELAPDQQHLSTEDLIKALRRRG 60
           MSLPPEKASELKQLIHQQLSKMDVHGRIREILAETIREELAPDQQHLSTEDLIKALRRRG
Sbjct: 1   MSLPPEKASELKQLIHQQLSKMDVHGRIREILAETIREELAPDQQHLSTEDLIKALRRRG 60

Query: 61  IIDDVMKELNFVTDSVEQELPSSPKQPICFDRQSTLKKTNIDPTRRYLYLQVLGGKAFLE 120
           IIDDVMKELNFVTDSVEQELPSSPKQPICFDRQSTLKKTNIDPTRRYLYLQVLGGKAFLE
Sbjct: 61  IIDDVMKELNFVTDSVEQELPSSPKQPICFDRQSTLKKTNIDPTRRYLYLQVLGGKAFLE 120

Query: 121 HLQEPEPLPGQVCSTFTLCLHYRNQRFRSKPVPCACEPDFHDGFLLEVHRESLGDGTRMA 180
           HLQEPEPLPGQVCSTFTLCLHYRNQRFRSKPVPCACEPDFHDGFLLEVHRESLGDGTRMA
Sbjct: 121 HLQEPEPLPGQVCSTFTLCLHYRNQRFRSKPVPCACEPDFHDGFLLEVHRESLGDGTRMA 180

Query: 181 DSTTMLSISDPIHMVLIKTDIFGETTLVASYFLEWRSVLGSENGVTSLTVELMGVGTESK 240
           DSTTMLSISDPIHMVLIKTDIFGETTLVASYFLEWRSVLGSENGVTSLTVELMGVGTESK
Sbjct: 181 DSTTMLSISDPIHMVLIKTDIFGETTLVASYFLEWRSVLGSENGVTSLTVELMGVGTESK 240

Query: 241 VSVGILNIKLEMYPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPS 300
           VSVGILNIKLEMYPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPS
Sbjct: 241 VSVGILNIKLEMYPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPS 300

Query: 301 HNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQAARFVNVLGYERAPVIGGGGKQ 360
           HNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQAARFVNVLGYERAPVIGGGGKQ
Sbjct: 301 HNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQAARFVNVLGYERAPVIGGGGKQ 360

Query: 361 EQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAI 420
           EQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAI
Sbjct: 361 EQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAI 420

Query: 421 TFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVF 480
           TFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVF
Sbjct: 421 TFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVF 480

Query: 481 DLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHR 540
           DLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHR
Sbjct: 481 DLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHR 540

Query: 541 KDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHF 600
           KDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHF
Sbjct: 541 KDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHF 600

Query: 601 VYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRSVL 659
           VYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRSVL
Sbjct: 601 VYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRSVL 659


>gi|229577352 coiled-coil and C2 domain containing 2B isoform 1
           [Homo sapiens]
          Length = 401

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 93/364 (25%), Positives = 152/364 (41%), Gaps = 45/364 (12%)

Query: 302 NSRLVKIFAQDENGINRPVCSYVKPLRAGR-LLD--------TPRQAARFVNVLGY-ERA 351
           N R+V     DE GI   V  Y+K L   + LLD        T    ARFV+++ +    
Sbjct: 64  NRRIVTTVFNDE-GIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNT 122

Query: 352 PVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWV 411
           P    G   + W T    +    G+ E+HA LLC+  L +G +A V +GT       A+V
Sbjct: 123 PDENDGS--DIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 412 MTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQP 471
           +T  T+  +  W   TG  Y             +Q  P  P +++ C+F+ +    N Q 
Sbjct: 181 VTQETNEYL-LWNPSTGQCY-------------KQFDPFCPLKSVDCLFDDRNVWFNIQQ 226

Query: 472 SDAVETCVFDLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTS--NEIE 529
           ++      FD + ES WK +  + ++         S+ P   +   T  + V    N IE
Sbjct: 227 NNTPMAVFFDYSKESFWKQLLPKNVQGT----KIQSIQPEEIIYFETDKSMVEDLRNRIE 282

Query: 530 MQLRLLVSEHRKDLGLTTVWEDQLSYLLSPALASYEFERTTSISA-GNEEFQDAIRRAVP 588
             L+  V E R      T W  Q +++L   L   EF   + +S+ G+ EF+  ++    
Sbjct: 283 RTLKSKVMEWRPK--HPTHWNRQCTFILRQILPKLEFGIGSFVSSEGDNEFERILQ---- 336

Query: 589 DGHTFKGFPIHFVYRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVW 648
             +   GFPI   Y + +    + + + +   I      Q   A+ V +  YP +  +VW
Sbjct: 337 -FYWVTGFPIQMPYIDVQ----SIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVW 391

Query: 649 IMFA 652
           +  A
Sbjct: 392 VYLA 395


>gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo
            sapiens]
          Length = 1620

 Score = 66.2 bits (160), Expect = 9e-11
 Identities = 89/416 (21%), Positives = 164/416 (39%), Gaps = 44/416 (10%)

Query: 253  YPPLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPSHNSRLVKIFAQD 312
            Y  L  T+  ++V  +   E+ ++ E E+L  + A + ++    ++  +   L  +   D
Sbjct: 1237 YITLFITIEPQLVPGESIREKFESQEDEKL--LQATEKFQAECALKFPNRQCLTTVI--D 1292

Query: 313  ENGINRPVCSYVKPLRA---------GRLLDTPRQAARFVNVLGYERAPVIGGGGKQEQW 363
             +G    +  Y+KPL             L  T    AR+V+++ +     +  GG  + W
Sbjct: 1293 ISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPF-LPDTVSFGGICDLW 1351

Query: 364  CTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAITFW 423
             T   FL    GD E+HA LLC+  L  G +A++ +G      P A+V+T    G    W
Sbjct: 1352 STSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLT-WEQGRYLIW 1410

Query: 424  ESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVFDLN 483
               +GH Y              Q     P + +GC+        N Q  ++     FD+ 
Sbjct: 1411 NPCSGHFY-------------GQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVT 1457

Query: 484  DESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHRKDL 543
                WK       +S+  PG ++  P    L     D +  + E++ ++  ++ E   D 
Sbjct: 1458 RPKLWKSFFS---RSLPYPGLSSVQP--EELIYQRSDKAAAA-ELQDRIEKILKEKIMDW 1511

Query: 544  --GLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHFV 601
                 T W    +  L   L   E  +   +    ++ +  + + + D + F GFP+H  
Sbjct: 1512 RPRHLTRWNRYCTSTLRHFLPLLEKSQGEDV---EDDHRAELLKQLGD-YRFSGFPLHMP 1567

Query: 602  YRNARRAFATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRS 657
            Y   +      + + +   +       V  A+ V +  YP++  +VWI  A   R+
Sbjct: 1568 YSEVK----PLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRN 1619


>gi|197209817 coiled-coil and C2 domain containing 2A isoform b [Homo
            sapiens]
          Length = 1512

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 77/349 (22%), Positives = 135/349 (38%), Gaps = 40/349 (11%)

Query: 320  VCSYVKPLRA---------GRLLDTPRQAARFVNVLGYERAPVIGGGGKQEQWCTLLAFL 370
            +  Y+KPL             L  T    AR+V+++ +     +  GG  + W T   FL
Sbjct: 1192 ITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPF-LPDTVSFGGICDLWSTSDQFL 1250

Query: 371  CRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWVMTCGTDGAITFWESLTGHR 430
                GD E+HA LLC+  L  G +A++ +G      P A+V+T    G    W   +GH 
Sbjct: 1251 DLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLT-WEQGRYLIWNPCSGHF 1309

Query: 431  YIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQPSDAVETCVFDLNDESKWKP 490
            Y              Q     P + +GC+        N Q  ++     FD+     WK 
Sbjct: 1310 Y-------------GQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKS 1356

Query: 491  MSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHRKDL--GLTTV 548
                  +S+  PG ++  P    L     D +  + E++ ++  ++ E   D      T 
Sbjct: 1357 FFS---RSLPYPGLSSVQP--EELIYQRSDKAAAA-ELQDRIEKILKEKIMDWRPRHLTR 1410

Query: 549  WEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPDGHTFKGFPIHFVYRNARRA 608
            W    +  L   L   E  +   +    ++ +  + + + D + F GFP+H  Y   +  
Sbjct: 1411 WNRYCTSTLRHFLPLLEKSQGEDV---EDDHRAELLKQLGD-YRFSGFPLHMPYSEVK-- 1464

Query: 609  FATCLRSPFCEEIICCRGDQVRLAVRVRVFTYPESACAVWIMFACKYRS 657
                + + +   +       V  A+ V +  YP++  +VWI  A   R+
Sbjct: 1465 --PLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRN 1511


>gi|109452583 coiled-coil and C2 domain containing 2B isoform 2
           [Homo sapiens]
          Length = 322

 Score = 56.6 bits (135), Expect = 7e-08
 Identities = 57/200 (28%), Positives = 87/200 (43%), Gaps = 27/200 (13%)

Query: 302 NSRLVKIFAQDENGINRPVCSYVKPLRAGR-LLD--------TPRQAARFVNVLGY-ERA 351
           N R+V     DE GI   V  Y+K L   + LLD        T    ARFV+++ +    
Sbjct: 64  NRRIVTTVFNDE-GIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNT 122

Query: 352 PVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWV 411
           P    G   + W T    +    G+ E+HA LLC+  L +G +A V +GT       A+V
Sbjct: 123 PDENDGS--DIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 412 MTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQP 471
           +T  T+  +  W   TG  Y             +Q  P  P +++ C+F+ +    N Q 
Sbjct: 181 VTQETNEYL-LWNPSTGQCY-------------KQFDPFCPLKSVDCLFDDRNVWFNIQQ 226

Query: 472 SDAVETCVFDLNDESKWKPM 491
           ++      FD + ES WK +
Sbjct: 227 NNTPMAVFFDYSKESFWKQL 246


>gi|223941912 coiled-coil domain containing 135 [Homo sapiens]
          Length = 874

 Score = 32.3 bits (72), Expect = 1.4
 Identities = 14/26 (53%), Positives = 20/26 (76%), Gaps = 1/26 (3%)

Query: 374 KGDCEDHANLLCSLLLGYGLEAFVCV 399
           KG+C D + LLCS+L+G G +A+ CV
Sbjct: 183 KGNCFDFSTLLCSMLIGSGYDAY-CV 207


>gi|110611228 utrophin [Homo sapiens]
          Length = 3433

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 18/109 (16%)

Query: 481  DLNDESKWKPMSEEAIKSVCAPGATTSLPPFPPLCASTIDASVTSNEIEMQLRLLVSEHR 540
            DLND ++W   +EE +   CAPG +  L            A +   E+E+     +S H+
Sbjct: 1984 DLNDLTQWITEAEELLVDTCAPGGSLDLE----------KARIHQQELEVG----ISSHQ 2029

Query: 541  KDLGLTTVWEDQLSYLLSPALASYEFERTTSISAGNEEFQDAIRRAVPD 589
                      D +   LS A  S+  E+     AG  +  DAI   V D
Sbjct: 2030 PSFAALNRTGDGIVQKLSQADGSFLKEKL----AGLNQRWDAIVAEVKD 2074


>gi|42734401 testis-specific serine kinase 4 [Homo sapiens]
          Length = 328

 Score = 32.0 bits (71), Expect = 1.9
 Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 255 PLNQTLSQEVVNTQLALERQKTAEKERLFLVYAKQWWREYLQIRPSHNSRLVKIFAQDEN 314
           P N T+SQE  N  L + RQ T ++  +  +    W  ++   +P+H  RL++   Q  N
Sbjct: 258 PANHTISQECKNLILQMLRQAT-KRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHN 316


>gi|221316699 maltase-glucoamylase [Homo sapiens]
          Length = 1857

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 418 GAITFW---ESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGN 468
           GA TF+   E  +G  +     N +   V  QP P   YRTIG + +  +FLGN
Sbjct: 301 GAQTFFLCLEDASGLSFGVFLMNSNAMEVVLQPAPAITYRTIGGILDFYVFLGN 354


>gi|239747812 PREDICTED: ankyrin repeat domain 36 [Homo sapiens]
          Length = 753

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 22/78 (28%), Positives = 32/78 (41%), Gaps = 4/78 (5%)

Query: 298 RPSHNSRLVKIFAQDENGINRPVCSYVKPLRAGRLLDTPRQA----ARFVNVLGYERAPV 353
           RP   +RL    A    G +    +     RA R +  PR      A+   + GY   P 
Sbjct: 261 RPWGRARLALQGAPPSRGTSAATAACTGRARAARAVSLPRACWAGPAKVRVLAGYNLQPT 320

Query: 354 IGGGGKQEQWCTLLAFLC 371
           I    ++E+W TL+  LC
Sbjct: 321 IKEDDERERWPTLMERLC 338


>gi|40255272 xin actin-binding repeat containing 1 [Homo sapiens]
          Length = 1843

 Score = 30.8 bits (68), Expect = 4.1
 Identities = 34/121 (28%), Positives = 58/121 (47%), Gaps = 24/121 (19%)

Query: 1   MSLPPEKASELKQLIHQQLSKM-----DVHGRIREILAETIREELAPD-QQHLSTEDLIK 54
           + LPP K S  K    +Q S++      +H  +R+ LAE + E+LA        TE  ++
Sbjct: 33  LPLPPPKESFSKFHQQRQASELRRLYRHIHPELRKNLAEAVAEDLAEVLGSEEPTEGDVQ 92

Query: 55  ALRRRGIIDDVMKELNFVTDSV-EQELPSSPKQPICFDRQSTLKK---------TNIDPT 104
            +  R I +      N+  D++ E E P++ +  +C D Q+T +K         T+ +PT
Sbjct: 93  CM--RWIFE------NWRLDAIGEHERPAAKEPVLCGDVQATSRKFEEGSFANSTDQEPT 144

Query: 105 R 105
           R
Sbjct: 145 R 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.136    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,947,628
Number of Sequences: 37866
Number of extensions: 1269994
Number of successful extensions: 3288
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3266
Number of HSP's gapped (non-prelim): 15
length of query: 659
length of database: 18,247,518
effective HSP length: 109
effective length of query: 550
effective length of database: 14,120,124
effective search space: 7766068200
effective search space used: 7766068200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.