Guide to the Human Genome
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Search of human proteins with 212286159

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212286159 mediator of cell motility 1 isoform 2 [Homo
sapiens]
         (274 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens]     562   e-160
gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens]       549   e-156
gi|74229025 membralin isoform 1 [Homo sapiens]                         32   0.60 
gi|15529970 membralin isoform 2 [Homo sapiens]                         32   0.60 
gi|21361625 Sec5 protein [Homo sapiens]                                31   1.0  
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa...    29   3.9  

>gi|212286159 mediator of cell motility 1 isoform 2 [Homo sapiens]
          Length = 274

 Score =  562 bits (1448), Expect = e-160
 Identities = 274/274 (100%), Positives = 274/274 (100%)

Query: 1   MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPRRIFILGPSHHV 60
           MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPRRIFILGPSHHV
Sbjct: 1   MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPRRIFILGPSHHV 60

Query: 61  PLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKA 120
           PLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKA
Sbjct: 61  PLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFERMSLQTDEDEHSIEMHLPYTAKA 120

Query: 121 MESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYD 180
           MESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYD
Sbjct: 121 MESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADPSNLFVVSSDFCHWGQRFRYSYYD 180

Query: 181 ESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKNG 240
           ESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKNG
Sbjct: 181 ESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYHNTICGRHPIGVLLNAITELQKNG 240

Query: 241 MNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH 274
           MNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH
Sbjct: 241 MNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH 274


>gi|7705720 mediator of cell motility 1 isoform 1 [Homo sapiens]
          Length = 297

 Score =  549 bits (1414), Expect = e-156
 Identities = 274/297 (92%), Positives = 274/297 (92%), Gaps = 23/297 (7%)

Query: 1   MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAP------------ 48
           MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAP            
Sbjct: 1   MSNRVVCREASHAGSWYTASGPQLNAQLEGWLSQVQSTKRPARAIIAPHAGYTYCGSCAA 60

Query: 49  -----------RRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFE 97
                      RRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFE
Sbjct: 61  HAYKQVDPSITRRIFILGPSHHVPLSRCALSSVDIYRTPLYDLRIDQKIYGELWKTGMFE 120

Query: 98  RMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADP 157
           RMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADP
Sbjct: 121 RMSLQTDEDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLADP 180

Query: 158 SNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYH 217
           SNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYH
Sbjct: 181 SNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQLDPVSFSNYLKKYH 240

Query: 218 NTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH 274
           NTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH
Sbjct: 241 NTICGRHPIGVLLNAITELQKNGMNMSFSFLNYAQSSQCRNWQDSSVSYAAGALTVH 297


>gi|74229025 membralin isoform 1 [Homo sapiens]
          Length = 620

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 17/52 (32%), Positives = 27/52 (51%)

Query: 105 EDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLAD 156
           +DE+ +E  L Y    +     +   IPV+V  L  +++Q FG  FS+ L D
Sbjct: 206 QDEYIVEYSLEYGFLRLSQATRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLD 257


>gi|15529970 membralin isoform 2 [Homo sapiens]
          Length = 408

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 17/52 (32%), Positives = 27/52 (51%)

Query: 105 EDEHSIEMHLPYTAKAMESHKDEFTIIPVLVGALSESKEQEFGKLFSKYLAD 156
           +DE+ +E  L Y    +     +   IPV+V  L  +++Q FG  FS+ L D
Sbjct: 206 QDEYIVEYSLEYGFLRLSQATRQRLSIPVMVVTLDPTRDQCFGDRFSRLLLD 257


>gi|21361625 Sec5 protein [Homo sapiens]
          Length = 924

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 18/84 (21%), Positives = 40/84 (47%), Gaps = 1/84 (1%)

Query: 146 FGKLFSKY-LADPSNLFVVSSDFCHWGQRFRYSYYDESQGEIYRSIEHLDKMGMSIIEQL 204
           FG +   + L     L +V S+ C+  +    +  +  +   ++ IE + ++ M+ +++L
Sbjct: 696 FGSIHEDFSLTSEQRLLIVLSNCCYLERHTFLNIAEHFEKHNFQGIEKITQVSMASLKEL 755

Query: 205 DPVSFSNYLKKYHNTICGRHPIGV 228
           D   F NY++   + I G    G+
Sbjct: 756 DQRLFENYIELKADPIVGSLEPGI 779


>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
          sapiens]
          Length = 349

 Score = 29.3 bits (64), Expect = 3.9
 Identities = 12/30 (40%), Positives = 17/30 (56%)

Query: 21 GPQLNAQLEGWLSQVQSTKRPARAIIAPRR 50
          GPQL A L  W++ V +T  P  A + P +
Sbjct: 7  GPQLTALLAAWIAAVAATAGPEEAALPPEQ 36


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,033,876
Number of Sequences: 37866
Number of extensions: 416036
Number of successful extensions: 883
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 876
Number of HSP's gapped (non-prelim): 6
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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