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Search of human proteins with 205277441
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|205277441 serine (or cysteine) proteinase inhibitor, clade
A, member 7 [Homo sapiens]
(415 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 825 0.0
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 409 e-114
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 330 1e-90
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 328 4e-90
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 322 3e-88
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 305 4e-83
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 305 4e-83
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 305 4e-83
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 305 4e-83
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 296 2e-80
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 285 5e-77
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 270 1e-72
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 252 5e-67
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 193 3e-49
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 189 4e-48
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 189 4e-48
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 187 1e-47
gi|170295807 neuroserpin precursor [Homo sapiens] 171 1e-42
gi|4826904 neuroserpin precursor [Homo sapiens] 171 1e-42
gi|73858566 heparin cofactor II precursor [Homo sapiens] 168 7e-42
gi|167860126 serine (or cysteine) proteinase inhibitor, clade B ... 165 8e-41
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 164 2e-40
gi|17998551 serine (or cysteine) proteinase inhibitor, clade B (... 158 8e-39
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 825 bits (2132), Expect = 0.0
Identities = 415/415 (100%), Positives = 415/415 (100%)
Query: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE
Sbjct: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN
Sbjct: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ
Sbjct: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ
Sbjct: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW
Sbjct: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK
Sbjct: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA 415
GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA
Sbjct: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA 415
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 409 bits (1050), Expect = e-114
Identities = 211/417 (50%), Positives = 289/417 (69%), Gaps = 2/417 (0%)
Query: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACH--SSQPNATLYKMSSINADFAFNLYRRFT 58
M+ +LY VL +GL A I+C SP +A SS + ++ S+N DFAF LYRR
Sbjct: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
Query: 59 VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICS 118
+ETP +NIFFSPVS+S +L MLS GA T+T+I++ LGFNLT TP I GFQHL+ S
Sbjct: 79 LETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHS 138
Query: 119 LNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVE 178
L P K+L L++G+ALF+ K L+ A FL +VK LYE EVFSTDFSN S A+ INSHV+
Sbjct: 139 LTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVK 198
Query: 179 MQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMM 238
+T+GKVV +IQ L T MVLVN+I FKA+W PF P T + FL+ + TV VPMM
Sbjct: 199 KKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMM 258
Query: 239 HQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQK 298
HQ EQ+ VD ELNC VLQMDY +A+A FVLP +G+M +E A+S++TL+KW+ LQK
Sbjct: 259 HQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQK 318
Query: 299 GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIG 358
W+++F+P+FSISA+Y+L L KMGIQ+ + +NADFSG+ + + L++S A HKAVL +
Sbjct: 319 RWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVS 378
Query: 359 EKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTEA 415
E+GTEA A + + ++ + + +R+F+++I ++T ILFLGKV NPT++
Sbjct: 379 EEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 435
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 330 bits (847), Expect = 1e-90
Identities = 185/423 (43%), Positives = 265/423 (62%), Gaps = 16/423 (3%)
Query: 6 YLVLLVLGLHATIHCA-SPEGKVTACHSSQPNATL--------YKMSSINADFAFNLYRR 56
YL+LL++GL A H E +C +S L K++ NADFAF Y
Sbjct: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYL 65
Query: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116
ETP KNIFFSP+SISAA MLS GAC ++++I+E LGFNLT+ ++ GFQHL+
Sbjct: 66 IASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLL 125
Query: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176
+LN P LE ++G+ALF+ +LK LAKFLND +YE ++F T+F + Q IN H
Sbjct: 126 HTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDH 185
Query: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236
V+ +T+GK+V L+ +LK + +MVLVNYI+FKA W PF S+T F +D+ TTV+VP
Sbjct: 186 VKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRT-TPKDFYVDENTTVRVP 244
Query: 237 MMHQ-MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRL 295
MM Q E +++L D L C+VL+MDY +A F+LP +G+M +E ++ + L +WN L
Sbjct: 245 MMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNL 304
Query: 296 LQK----GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAH 351
L+K ++L +PKFSIS +Y L L ++G +S+ AD SG+T+ L+ S + H
Sbjct: 305 LRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFH 364
Query: 352 KAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVN 411
KA L + E GTEAAA + T H I++ +R F+++I ST+S+LFLGKVV+
Sbjct: 365 KATLDVDEAGTEAAAATSFAIKFFSAQTNRH-ILRFNRPFLVVIFSTSTQSVLFLGKVVD 423
Query: 412 PTE 414
PT+
Sbjct: 424 PTK 426
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 328 bits (842), Expect = 4e-90
Identities = 180/417 (43%), Positives = 260/417 (62%), Gaps = 12/417 (2%)
Query: 6 YLVLLVLGLHATIHCA--------SPEGKVTACHS-SQPNATLYKMSSINADFAFNLYRR 56
+L LL G+ A++HC S +G H S+P ++++ +FA LY+
Sbjct: 5 WLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKE 64
Query: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116
+ P NIFFSPVSIS L +LS GA +T I+E LGFNLT+TP +I GF+ L+
Sbjct: 65 LAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLL 123
Query: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176
+L P +LEL++GN+LF+ K LKP +L+ +K LY FS +F++ ++IN +
Sbjct: 124 HTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDY 183
Query: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236
+ QT G+VV + + +T MVL NYI FKA+W +PF +T+ SF +D+ T++QVP
Sbjct: 184 LRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVP 243
Query: 237 MMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLL 296
MMHQ E + L D +L CTVLQ++Y NALAL VLP G+M+ VEAA+ +TL+KW +LL
Sbjct: 244 MMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLL 303
Query: 297 QKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLH 356
+DL +P+FSIS TY+L L ++G+ + + ADFSG+T +S +HKA++
Sbjct: 304 LPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVD 363
Query: 357 IGEKGTEAAAVPEVELSDQPE-NTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
+ EKGTEA A + LS P NT P +R F+LL+ E +T+S+LFLGKVVNP
Sbjct: 364 MSEKGTEAGAASGL-LSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 322 bits (826), Expect = 3e-88
Identities = 182/423 (43%), Positives = 261/423 (61%), Gaps = 11/423 (2%)
Query: 1 MSPFLYLVLLVLGLHATIHCA--SPEGKVTACHSSQPNATLYKM--SSINADFAFNLYRR 56
M P L L LL G + C SP + +Q T + +S N DFAF+LY++
Sbjct: 4 MLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQ 63
Query: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116
++ PDKN+ FSP+SIS AL LS GA +T TEI++ L FNLT+T EI FQHL+
Sbjct: 64 LVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLL 123
Query: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176
+LN EL+L +GNA+F+ + L L +F D K LY +E F+TDF + +AAK+ IN +
Sbjct: 124 RTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDY 183
Query: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236
V+ T+GK+ LI+DL T+MVLVNYI FKA+W PFDP T S F + K V VP
Sbjct: 184 VKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH-QSRFYLSKKKWVMVP 242
Query: 237 MM---HQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWN 293
MM H Y+ D EL+CTV+++ Y+ NA ALF+LP + +ME VEA + +TLK+W
Sbjct: 243 MMSLHHLTIPYFR--DEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWR 300
Query: 294 RLLQKGWV-DLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHK 352
L+ + +L++PKFSIS Y+L LL++GI+ A++ AD SG+T L +S HK
Sbjct: 301 DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHK 360
Query: 353 AVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
AVL + E+GTEA+A V+++ I++ +R F+++I+ T++I F+ KV NP
Sbjct: 361 AVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
Query: 413 TEA 415
+A
Sbjct: 421 KQA 423
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 305 bits (782), Expect = 4e-83
Identities = 171/414 (41%), Positives = 252/414 (60%), Gaps = 12/414 (2%)
Query: 8 VLLVLGLHATIHCA---SPEG----KVTACHSSQPNATLYKMSSINADFAFNLYRRFTVE 60
+LL+ GL + + P+G K H Q + T K++ A+FAF+LYR+ +
Sbjct: 9 ILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 61 TPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLN 120
+ NIFFSPVSI+ A MLS G T EI+E L FNLT+ P +I GFQ L+ +LN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 121 FPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQ 180
P +L+L GN LF+ + LK + KFL DVK LY +E F+ +F + AK++IN +VE
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 181 TKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQ 240
T+GK+V L+++L +T+ LVNYI FK +W PF+ TE+ F +D+ TTV+VPMM +
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEE-EDFHVDQVTTVKVPMMKR 247
Query: 241 MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGW 300
+ + +L+ VL M Y NA A+F LP EG+++ +E ++ + K+ +
Sbjct: 248 LGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRRS 307
Query: 301 VDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEK 360
L +PK SI+ TYDL + L ++GI +S AD SG+TE+ LKLS A HKAVL I EK
Sbjct: 308 ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEK 367
Query: 361 GTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNPTE 414
GTEAA +E + P ++ ++ F+ L++E++T+S LF+GKVVNPT+
Sbjct: 368 GTEAAGAMFLEAIPMS----IPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 296 bits (758), Expect = 2e-80
Identities = 166/398 (41%), Positives = 234/398 (58%), Gaps = 14/398 (3%)
Query: 23 PEGKVTACHSSQPNATLYKMS-------SINADFAFNLYRRFTVETPDKNIFFSPVSISA 75
P + + PNA MS S N DFAF+LY+ +P KNIF SPVSIS
Sbjct: 13 PTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISM 72
Query: 76 ALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALF 135
AL MLS G C T+ ++++ LGFNLT+ EI GFQHL LE+ +GNALF
Sbjct: 73 ALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALF 132
Query: 136 IGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPN 195
+ L+ L F D+K YE+EV + +F + + A ++INS+V+ +T+GK+V L L
Sbjct: 133 LDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSP 192
Query: 196 TIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCT 255
I+VLVNYI FK W PFD + T + + F +D+TT V+VPMM Q +L D EL C
Sbjct: 193 AILVLVNYIFFKGTWTQPFDLASTREEN-FYVDETTVVKVPMMLQSSTISYLHDAELPCQ 251
Query: 256 VLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYD 315
++QM+Y N F+LP +G+M +V AA+S T+ +W+ L VDL++PK +IS YD
Sbjct: 252 LVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYD 311
Query: 316 LGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQ 375
LG L +MGI ++ A+FS +T+D LK S HKAVL + E+G + A V L
Sbjct: 312 LGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTL--- 368
Query: 376 PENTFLHPII-QIDRSFMLLILERSTRSILFLGKVVNP 412
N PII + ++ F+++I + T S LFL +V+NP
Sbjct: 369 --NLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 285 bits (729), Expect = 5e-77
Identities = 158/413 (38%), Positives = 245/413 (59%), Gaps = 8/413 (1%)
Query: 1 MSPFLYLVLLVLGLH-ATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTV 59
M FL L L++L A++H P AT+ S DF F+LYR
Sbjct: 1 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSS--RRDFTFDLYRALAS 58
Query: 60 ETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSL 119
P ++IFFSPVSIS +L MLS GA ST+ +I+E LG NL + E+ GFQ L+ L
Sbjct: 59 AAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQEL 118
Query: 120 NFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEM 179
N P+ +L +GNALF + F++ +KTLY + F T+F + + A ++IN +V
Sbjct: 119 NQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAK 178
Query: 180 QTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMH 239
QTKGK+V L+++L N ++++VNYI FKA+W F+ T++ F + T V+VPMM
Sbjct: 179 QTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQE-QDFYVTSETVVRVPMMS 237
Query: 240 QMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKG 299
+ +QY++L+D L+C V+ + Y NA ALF+LP EG+M+ VE +S KTL+KW ++ +K
Sbjct: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
Query: 300 WVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGE 359
++L++PKFSI +Y L L +GI + ++ +AD SG++ + +++S HKAV+ + E
Sbjct: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
Query: 360 KGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
GT AAA + + ++ +R F++ I++ +ILFLGKV P
Sbjct: 358 SGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNRP 406
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 270 bits (691), Expect = 1e-72
Identities = 141/367 (38%), Positives = 217/367 (59%), Gaps = 7/367 (1%)
Query: 46 NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPM 105
N D F L ++ P +NIF SP+SIS A ML GA ST EI + GFN P
Sbjct: 52 NMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQ--GFNFRKMPE 109
Query: 106 VEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSN 165
++ GF ++I L ++L+L IGN LFI + L+P KFL D K Y E T+F N
Sbjct: 110 KDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQN 169
Query: 166 ISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSF 225
+ A+++IN + +T GK+ LI+++ P T+M+L NYI F+A+W + FDP+ T++ F
Sbjct: 170 LEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE-EDF 228
Query: 226 LIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMS 285
++K ++V+VPMM + Y D +L+CT+L++ Y KN A+F+LP EG+++ +E +
Sbjct: 229 FLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQ 288
Query: 286 SKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLK 345
T +W LL + VD+ VP+ ++ T+DL TL +G+ + E+ D + + LK
Sbjct: 289 VDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLK 348
Query: 346 LSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILF 405
+ A HKA L + E+GTE AA + P T L +++ID+ ++LLI S+LF
Sbjct: 349 VGEAVHKAELKMDERGTEGAAGTGAQ--TLPMETPL--VVKIDKPYLLLIYSEKIPSVLF 404
Query: 406 LGKVVNP 412
LGK+VNP
Sbjct: 405 LGKIVNP 411
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 252 bits (643), Expect = 5e-67
Identities = 126/263 (47%), Positives = 179/263 (68%)
Query: 153 LYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWAN 212
LY V T NI + INSHV+ +T+GKVV +IQ L T MVLVN+I FKA+W
Sbjct: 73 LYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEK 132
Query: 213 PFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLP 272
PF P T + FL+ + TV VPMMHQ EQ+ VD ELNC VLQMDY +A+A FVLP
Sbjct: 133 PFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLP 192
Query: 273 KEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 332
+G+M +E A+S++TL+KW+ LQK W+++F+P+FSISA+Y+L L KMGIQ+ + +N
Sbjct: 193 SKGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKN 252
Query: 333 ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFM 392
ADFSG+ + + L++S A HKAVL + E+GTEA A + + ++ + + +R+F+
Sbjct: 253 ADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFL 312
Query: 393 LLILERSTRSILFLGKVVNPTEA 415
++I ++T ILFLGKV NPT++
Sbjct: 313 MMITNKATDGILFLGKVENPTKS 335
Score = 68.2 bits (165), Expect = 1e-11
Identities = 45/115 (39%), Positives = 65/115 (56%), Gaps = 11/115 (9%)
Query: 1 MSPFLYLVLLVLGLHATIHCASPEGKVTACH--SSQPNATLYKMSSINADFAFNLYRRFT 58
M+ +LY VL +GL A I+C SP +A SS + ++ S+N DFAF LYRR
Sbjct: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
Query: 59 VETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL-GFNLTDTPMVEIQHGF 112
+ETP +NIFFSP I++ + TQ ++V+ + G +L T MV + H F
Sbjct: 79 LETPSQNIFFSPARINSHVKK-------KTQGKVVDIIQGLDLL-TAMVLVNHIF 125
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 193 bits (490), Expect = 3e-49
Identities = 134/396 (33%), Positives = 211/396 (53%), Gaps = 34/396 (8%)
Query: 42 MSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLT 101
+S N F F+L+++F ++ + NIF+SP+SI++AL M+ GA +T +I + L F+
Sbjct: 4 LSEANTKFMFDLFQQFR-KSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQV 62
Query: 102 DTPMVE------------IQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLND 149
E + H FQ L+ N EL+I N LF K + L ++L+
Sbjct: 63 TENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDA 122
Query: 150 VKTLYETEVFSTDFSNI-SAAKQEINSHVEMQTKGKVVGLIQD--LKPNTIMVLVNYIHF 206
+K Y+T V STDF+N ++++INS VE QT K+ L D + +T +VLVN I+F
Sbjct: 123 IKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYF 182
Query: 207 KAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNAL 266
K QW N F T++ F +K T V MM Q + + ++ VL++ Y L
Sbjct: 183 KGQWENKFKKENTKEEK-FWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDL 241
Query: 267 ALFVL-PKE-GQMESVEAAMSSKTLKKWNRL--LQKGWVDLFVPKFSISATYDLGATLLK 322
++ VL P E ++ +E ++++ L +W L +++ VDL +P+F + +YDL TL
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRT 301
Query: 323 MGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAA---AVPEVELSDQPENT 379
MG+ + ++ +AD SG+T +GL +S HKA + + E+G EAA AV VELS N
Sbjct: 302 MGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNE 361
Query: 380 FL---HPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
HP F+ I + T SILF G+ +P
Sbjct: 362 EFCCNHP-------FLFFIRQNKTNSILFYGRFSSP 390
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 189 bits (480), Expect = 4e-48
Identities = 125/382 (32%), Positives = 205/382 (53%), Gaps = 14/382 (3%)
Query: 37 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 96
A+ +++ ++F F+L R+ ++ D N+ FSP +S A+ L GA T+T+I L
Sbjct: 70 ASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128
Query: 97 GFN-LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYE 155
L T + F+ L +L+ EL L G+ FI K F N K ++
Sbjct: 129 HLQALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187
Query: 156 TEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFD 215
TE +F N S AK+ +N ++ +T+GK+ L ++ P T ++LV+YI FK +W PFD
Sbjct: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFD 247
Query: 216 PSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVL-PKE 274
P TE +F +DK T++VPMM+ ++ D C VL++ Y NA L VL K
Sbjct: 248 PVFTE-VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306
Query: 275 GQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD 334
G ++E +++ ++ W R ++ +++F PKF + Y++ L +MGI+ +S AD
Sbjct: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366
Query: 335 FSGLT-EDNGLKLSNAAHKAVLHIGEKGTEAAA--VPEVELSDQPENTFLHPIIQIDRSF 391
S L+ L++S + V+ + E+GTEA A + E+ P P+I++DR F
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP------PVIKVDRPF 420
Query: 392 MLLILERSTRSILFLGKVVNPT 413
+I E ++ +LFLG+VVNPT
Sbjct: 421 HFMIYEETSGMLLFLGRVVNPT 442
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 189 bits (480), Expect = 4e-48
Identities = 125/382 (32%), Positives = 205/382 (53%), Gaps = 14/382 (3%)
Query: 37 ATLYKMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 96
A+ +++ ++F F+L R+ ++ D N+ FSP +S A+ L GA T+T+I L
Sbjct: 70 ASRQQLAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 128
Query: 97 GFN-LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYE 155
L T + F+ L +L+ EL L G+ FI K F N K ++
Sbjct: 129 HLQALKPTKPGLLPSLFKGLRETLS-RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFD 187
Query: 156 TEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFD 215
TE +F N S AK+ +N ++ +T+GK+ L ++ P T ++LV+YI FK +W PFD
Sbjct: 188 TECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFD 247
Query: 216 PSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVL-PKE 274
P TE +F +DK T++VPMM+ ++ D C VL++ Y NA L VL K
Sbjct: 248 PVFTE-VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKM 306
Query: 275 GQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENAD 334
G ++E +++ ++ W R ++ +++F PKF + Y++ L +MGI+ +S AD
Sbjct: 307 GDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFAD 366
Query: 335 FSGLT-EDNGLKLSNAAHKAVLHIGEKGTEAAA--VPEVELSDQPENTFLHPIIQIDRSF 391
S L+ L++S + V+ + E+GTEA A + E+ P P+I++DR F
Sbjct: 367 LSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMP------PVIKVDRPF 420
Query: 392 MLLILERSTRSILFLGKVVNPT 413
+I E ++ +LFLG+VVNPT
Sbjct: 421 HFMIYEETSGMLLFLGRVVNPT 442
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 187 bits (476), Expect = 1e-47
Identities = 129/391 (32%), Positives = 206/391 (52%), Gaps = 24/391 (6%)
Query: 42 MSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGF--- 98
+S N F F+L+++F ++ + NIF+SP+SI++AL M+ GA +T +I + L F
Sbjct: 4 LSEANTKFMFDLFQQFR-KSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQV 62
Query: 99 --NLTDTPMV-------EIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLND 149
N T + H FQ L+ N EL+I N LF K L ++L+
Sbjct: 63 TENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDA 122
Query: 150 VKTLYETEVFSTDFSNI-SAAKQEINSHVEMQTKGKVVGLIQD--LKPNTIMVLVNYIHF 206
+K Y+T V S DF+N ++++INS VE QT K+ LI + + NT +VLVN I+F
Sbjct: 123 IKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYF 182
Query: 207 KAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNAL 266
K QW F+ T++ F +K T + MM Q ++ ++ VL++ Y L
Sbjct: 183 KGQWEKKFNKEDTKEEK-FWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDL 241
Query: 267 ALFVL-PKE-GQMESVEAAMSSKTLKKWNRL--LQKGWVDLFVPKFSISATYDLGATLLK 322
++ VL P E ++ +E ++++ L +W L +++ VDL +P+F + +YDL TL
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRT 301
Query: 323 MGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPE-VELSDQPENTFL 381
MG+ ++ +AD SG+T GL LS HKA + + E+G EAAA V P +T
Sbjct: 302 MGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTST-- 359
Query: 382 HPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
+ + F+ I + T SILF G+ +P
Sbjct: 360 NEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|170295807 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 171 bits (433), Expect = 1e-42
Identities = 109/377 (28%), Positives = 201/377 (53%), Gaps = 17/377 (4%)
Query: 47 ADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFN-LTDTPM 105
AD + N+Y R D+NI FSP+SI+ A+ M+ GA STQ EI ++G++ L +
Sbjct: 27 ADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEE 86
Query: 106 VEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSN 165
F +++ + + + ++I N+LF+ +FL +K + V DFS
Sbjct: 87 FSFLKEFSNMVTA---KESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
Query: 166 ISAAKQEINSHVEMQTKGKVVGLI--QDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSS 223
A IN VE T V L+ +D T + L+N ++FK W + F P T +
Sbjct: 144 NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TF 202
Query: 224 SFLIDKTTTVQVPMMHQMEQYYHLVDMELN------CTVLQMDYSKNALALFVL--PKEG 275
SF D + VQ+PMM+Q ++Y+ + + VL++ Y + +++ ++ +E
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 276 QMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADF 335
+ ++E + ++ +++W ++K V++++P+F++ DL L +GI + ++A+
Sbjct: 263 PLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANL 322
Query: 336 SGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLI 395
+GL+++ + LS A HK+ L + E+G+EAAAV + + L+P + +D F LI
Sbjct: 323 TGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISR--MAVLYPQVIVDHPFFFLI 380
Query: 396 LERSTRSILFLGKVVNP 412
R T +ILF+G+V++P
Sbjct: 381 RNRRTGTILFMGRVMHP 397
>gi|4826904 neuroserpin precursor [Homo sapiens]
Length = 410
Score = 171 bits (433), Expect = 1e-42
Identities = 109/377 (28%), Positives = 201/377 (53%), Gaps = 17/377 (4%)
Query: 47 ADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFN-LTDTPM 105
AD + N+Y R D+NI FSP+SI+ A+ M+ GA STQ EI ++G++ L +
Sbjct: 27 ADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKNGEE 86
Query: 106 VEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSN 165
F +++ + + + ++I N+LF+ +FL +K + V DFS
Sbjct: 87 FSFLKEFSNMVTA---KESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQ 143
Query: 166 ISAAKQEINSHVEMQTKGKVVGLI--QDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSS 223
A IN VE T V L+ +D T + L+N ++FK W + F P T +
Sbjct: 144 NVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTR-TF 202
Query: 224 SFLIDKTTTVQVPMMHQMEQYYHLVDMELN------CTVLQMDYSKNALALFVL--PKEG 275
SF D + VQ+PMM+Q ++Y+ + + VL++ Y + +++ ++ +E
Sbjct: 203 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 262
Query: 276 QMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADF 335
+ ++E + ++ +++W ++K V++++P+F++ DL L +GI + ++A+
Sbjct: 263 PLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANL 322
Query: 336 SGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLI 395
+GL+++ + LS A HK+ L + E+G+EAAAV + + L+P + +D F LI
Sbjct: 323 TGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISR--MAVLYPQVIVDHPFFFLI 380
Query: 396 LERSTRSILFLGKVVNP 412
R T +ILF+G+V++P
Sbjct: 381 RNRRTGTILFMGRVMHP 397
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 168 bits (426), Expect = 7e-42
Identities = 114/385 (29%), Positives = 198/385 (51%), Gaps = 16/385 (4%)
Query: 39 LYKMSSINADFAFNLYR--RFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETL 96
+ +++ +NA FAFNLYR + V T D NIF +PV IS A+ M+S G T ++ L
Sbjct: 123 IQRLNILNAKFAFNLYRVLKDQVNTFD-NIFIAPVGISTAMGMISLGLKGETHEQVHSIL 181
Query: 97 GFN-----LTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVK 151
F + + I + F+ L L L+ N L+I K L F V+
Sbjct: 182 HFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLYIQKQFPILLDFKTKVR 241
Query: 152 TLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWA 211
Y E DFS+ A + N+H+ TKG + ++++ P T M+++N I+FK W
Sbjct: 242 EYYFAEAQIADFSD-PAFISKTNNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWV 300
Query: 212 NPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVL 271
N F P + + +F +++ V+V MM + D EL+C +LQ++Y L V+
Sbjct: 301 NKF-PVEMTHNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVV 359
Query: 272 P-KEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYS 330
P K M+++EA ++ + +++W + + ++ +PKF + Y+L +L MGI+ +
Sbjct: 360 PHKMSGMKTLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFD 419
Query: 331 ENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRS 390
+N + +G++ D + + H+ + + E+GT+A V V P +T + +DR
Sbjct: 420 KNGNMAGIS-DQRIAIDLFKHQGTITVNEEGTQATTVTTVGF--MPLSTQVR--FTVDRP 474
Query: 391 FMLLILERSTRSILFLGKVVNPTEA 415
F+ LI E T +LF+G+V NP+ +
Sbjct: 475 FLFLIYEHRTSCLLFMGRVANPSRS 499
>gi|167860126 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 5 [Homo sapiens]
Length = 375
Score = 165 bits (417), Expect = 8e-41
Identities = 110/381 (28%), Positives = 198/381 (51%), Gaps = 27/381 (7%)
Query: 46 NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGF-NLTDTP 104
N+ FA +L+++ + P N+ FSP+ +S +L + GA T EI + L F N+ D P
Sbjct: 8 NSAFAVDLFKQLCEKEPLGNVLFSPICLSTSLSLAQVGAKGDTANEIGQVLHFENVKDVP 67
Query: 105 MVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFS 164
GFQ + +N L++ L++ K L +F++ K Y E+ + DF
Sbjct: 68 F-----GFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFK 122
Query: 165 N-ISAAKQEINSHVEMQTKGKVVGLIQDLKPN--TIMVLVNYIHFKAQWANPFDPSKTED 221
+ + K +IN+ ++ T G ++ D N T +++VN +F +W F S+T++
Sbjct: 123 DKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKE 182
Query: 222 SSSFLIDKTTTVQVPMMHQMEQYYHLVDME-LNCTVLQMDYSKNALALFVL-PKEGQ--- 276
F ++KT T V MM+ ME + + +++ +NC ++++ + L++F+L PK+ +
Sbjct: 183 CP-FRVNKTDTKPVQMMN-MEATFCMGNIDSINCKIIELPFQNKHLSMFILLPKDVEDES 240
Query: 277 --MESVEAAMSSKTLKKWNR--LLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSEN 332
+E +E ++S++L +W + V L +PKF + D A L +G++H +SE+
Sbjct: 241 TGLEKIEKQLNSESLSQWTNPSTMANAKVKLSIPKFKVEKMIDPKACLENLGLKHIFSED 300
Query: 333 -ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSF 391
+DFSG++E G+ LSN HK L I E G ++ VP + + + D F
Sbjct: 301 TSDFSGMSETKGVALSNVIHKVCLEITEDGGDSIEVPGARILQHKDE------LNADHPF 354
Query: 392 MLLILERSTRSILFLGKVVNP 412
+ +I TR+I+F GK +P
Sbjct: 355 IYIIRHNKTRNIIFFGKFCSP 375
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 164 bits (414), Expect = 2e-40
Identities = 128/397 (32%), Positives = 200/397 (50%), Gaps = 32/397 (8%)
Query: 43 SSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTD 102
+SIN FA L ++ KNIFFS SIS +L ++ GA +T ++ + L FN
Sbjct: 6 TSIN-QFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQ 64
Query: 103 ------------------TPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLA 144
+ EI FQ LI + P + L+ NA++ K
Sbjct: 65 GVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHN 124
Query: 145 KFLNDVKTLYETEVFSTDFSNIS-AAKQEINSHVEMQTKGKVVGLIQD--LKPNTIMVLV 201
K+L D+KT + E +F S +++INS VE QT+GK+ L+ D + T M+LV
Sbjct: 125 KYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILV 184
Query: 202 NYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTV-LQMD 260
N ++FK W + F T + F I++TT+ V MM M++ H+ +E V LQ+
Sbjct: 185 NALYFKGIWEHQFLVQNTTEKP-FRINETTSKPVQMMF-MKKKLHIFHIEKPKAVGLQLY 242
Query: 261 YSKNALALFVLPKE--GQMESVEAAMSSKTLKKWNR--LLQKGWVDLFVPKFSISATYDL 316
Y L+L +L E +E +E A++ + L +W +++ V L +PKF + +YDL
Sbjct: 243 YKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDL 302
Query: 317 GATLLKMGIQHAYSEN-ADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQ 375
+TL MG+ A+S++ ADFSG++ L LSN HKA + I E+GTEAAA E+ +
Sbjct: 303 KSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIR 362
Query: 376 PENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
+ + F+ I T +ILF G++ +P
Sbjct: 363 IRVPSIE--FNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|17998551 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 12 [Homo sapiens]
Length = 405
Score = 158 bits (400), Expect = 8e-39
Identities = 119/401 (29%), Positives = 194/401 (48%), Gaps = 37/401 (9%)
Query: 46 NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFN------ 99
N F F+L++ + KNIFFSP+S+SAAL M+ GA + +I E L FN
Sbjct: 8 NTKFCFDLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNE 67
Query: 100 -LTDTPMVE---------------IQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPL 143
P ++ + F L+ L+ K + L I N L+ +
Sbjct: 68 SKEPDPCLKSNKQKAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQEFPIC 127
Query: 144 AKFLNDVKTLYETEVFSTDFS-NISAAKQEINSHVEMQTKGKVVGLIQD--LKPNTIMVL 200
++L+ V Y T + S DF N ++QEIN VE Q++GK+ L + T++VL
Sbjct: 128 QEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVL 187
Query: 201 VNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMD 260
VN ++FKA+W FD T D + F ++ V MM Q Y E+ +L+M
Sbjct: 188 VNAVYFKAKWETYFDHENTVD-APFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMR 246
Query: 261 YSKNALALFV-LPKEGQ-----MESVEAAMSSKTLKKW--NRLLQKGWVDLFVPKFSISA 312
Y+K L++FV LP + +E +E ++ + + W + + + V L P+F++
Sbjct: 247 YTKGKLSMFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLED 306
Query: 313 TYDLGATLLKMGIQHAYSE-NADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVE 371
+YDL + L MGI + E AD +G++ L LS HK + + E GT+AAA
Sbjct: 307 SYDLNSILQDMGITDIFDETRADLTGISPSPNLYLSKIIHKTFVEVDENGTQAAAATGAV 366
Query: 372 LSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
+S++ +++ + F+ I T++ILF G+V +P
Sbjct: 367 VSERSLRSWVE--FNANHPFLFFIRHNKTQTILFYGRVCSP 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.384
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,018,385
Number of Sequences: 37866
Number of extensions: 561174
Number of successful extensions: 1498
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1254
Number of HSP's gapped (non-prelim): 66
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.