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Search of human proteins with 20302143
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|20302143 kallikrein-related peptidase 15 isoform 4
preproprotein [Homo sapiens]
(256 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprot... 543 e-155
gi|20302145 kallikrein-related peptidase 15 isoform 2 preproprot... 337 5e-93
gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 266 1e-71
gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens] 266 1e-71
gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens] 266 1e-71
gi|20302147 kallikrein-related peptidase 15 isoform 3 preproprot... 253 1e-67
gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens] 248 5e-66
gi|21464127 kallikrein 8 isoform 2 [Homo sapiens] 245 2e-65
gi|29366812 kallikrein-related peptidase 9 [Homo sapiens] 238 4e-63
gi|61744424 kallikrein-related peptidase 6 isoform A preproprote... 234 5e-62
gi|4506155 kallikrein-related peptidase 6 isoform A preproprotei... 234 5e-62
gi|91823048 kallikrein 14 preproprotein [Homo sapiens] 231 6e-61
gi|22208987 kallikrein 12 isoform 2 [Homo sapiens] 229 1e-60
gi|11496281 kallikrein 13 precursor [Homo sapiens] 223 1e-58
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens] 219 2e-57
gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo ... 218 3e-57
gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo ... 218 3e-57
gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo sa... 218 3e-57
gi|21327705 stratum corneum chymotryptic enzyme preproprotein [H... 216 2e-56
gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Ho... 216 2e-56
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens] 216 2e-56
gi|9665236 kallikrein 12 isoform 1 [Homo sapiens] 215 3e-56
gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens] 209 1e-54
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens] 207 9e-54
gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens] 205 4e-53
gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo... 201 4e-52
gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo ... 201 4e-52
gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo ... 201 4e-52
gi|4502173 prostate specific antigen isoform 1 preproprotein [Ho... 199 3e-51
gi|4504875 kallikrein 1 preproprotein [Homo sapiens] 192 2e-49
>gi|20302143 kallikrein-related peptidase 15 isoform 4 preproprotein
[Homo sapiens]
Length = 256
Score = 543 bits (1398), Expect = e-155
Identities = 256/256 (100%), Positives = 256/256 (100%)
Query: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA
Sbjct: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
Query: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
Query: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180
QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC
Sbjct: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180
Query: 181 DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYT 240
DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYT
Sbjct: 181 DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYT 240
Query: 241 KVCHYLEWIRETMKRN 256
KVCHYLEWIRETMKRN
Sbjct: 241 KVCHYLEWIRETMKRN 256
>gi|20302145 kallikrein-related peptidase 15 isoform 2 preproprotein
[Homo sapiens]
Length = 161
Score = 337 bits (865), Expect = 5e-93
Identities = 160/160 (100%), Positives = 160/160 (100%)
Query: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA
Sbjct: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
Query: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
Query: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQ 160
QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQ
Sbjct: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQ 160
>gi|209862865 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 266 bits (681), Expect = 1e-71
Identities = 129/258 (50%), Positives = 169/258 (65%), Gaps = 15/258 (5%)
Query: 4 LLTLSFLLASTAAQDGD-KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
+L L L +T G+ ++++G EC PHSQPWQ AL+E+ R CGA+LI+P W+L+AAH
Sbjct: 3 ILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE----ARSHRNDIMLLRLVQPARL 118
C V LG+HNL+K +G EQ RT + PHP + + HRNDIML+++ P +
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
VRP L +RC G +C++SGWG S SP Q+ LP TL CANI+II
Sbjct: 123 TWAVRPLTLSSRCVTAGTSCLISGWGSTS--------SP--QLRLPHTLRCANITIIEHQ 172
Query: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
C+ +YPG +T+TMVCA + G +SC+GDSGGPLVC LQGI+SWG PC T KPGV
Sbjct: 173 KCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 232
Query: 239 YTKVCHYLEWIRETMKRN 256
YTKVC Y++WI+ETMK N
Sbjct: 233 YTKVCKYVDWIQETMKNN 250
>gi|21618357 kallikrein 11 isoform 2 precursor [Homo sapiens]
Length = 282
Score = 266 bits (681), Expect = 1e-71
Identities = 129/258 (50%), Positives = 169/258 (65%), Gaps = 15/258 (5%)
Query: 4 LLTLSFLLASTAAQDGD-KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
+L L L +T G+ ++++G EC PHSQPWQ AL+E+ R CGA+LI+P W+L+AAH
Sbjct: 35 ILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 94
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE----ARSHRNDIMLLRLVQPARL 118
C V LG+HNL+K +G EQ RT + PHP + + HRNDIML+++ P +
Sbjct: 95 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 154
Query: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
VRP L +RC G +C++SGWG S SP Q+ LP TL CANI+II
Sbjct: 155 TWAVRPLTLSSRCVTAGTSCLISGWGSTS--------SP--QLRLPHTLRCANITIIEHQ 204
Query: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
C+ +YPG +T+TMVCA + G +SC+GDSGGPLVC LQGI+SWG PC T KPGV
Sbjct: 205 KCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 264
Query: 239 YTKVCHYLEWIRETMKRN 256
YTKVC Y++WI+ETMK N
Sbjct: 265 YTKVCKYVDWIQETMKNN 282
>gi|5803199 kallikrein 11 isoform 1 preproprotein [Homo sapiens]
Length = 250
Score = 266 bits (681), Expect = 1e-71
Identities = 129/258 (50%), Positives = 169/258 (65%), Gaps = 15/258 (5%)
Query: 4 LLTLSFLLASTAAQDGD-KLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
+L L L +T G+ ++++G EC PHSQPWQ AL+E+ R CGA+LI+P W+L+AAH
Sbjct: 3 ILQLILLALATGLVGGETRIIKGFECKPHSQPWQAALFEKTRLLCGATLIAPRWLLTAAH 62
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE----ARSHRNDIMLLRLVQPARL 118
C V LG+HNL+K +G EQ RT + PHP + + HRNDIML+++ P +
Sbjct: 63 CLKPRYIVHLGQHNLQKEEGCEQTRTATESFPHPGFNNSLPNKDHRNDIMLVKMASPVSI 122
Query: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
VRP L +RC G +C++SGWG S SP Q+ LP TL CANI+II
Sbjct: 123 TWAVRPLTLSSRCVTAGTSCLISGWGSTS--------SP--QLRLPHTLRCANITIIEHQ 172
Query: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
C+ +YPG +T+TMVCA + G +SC+GDSGGPLVC LQGI+SWG PC T KPGV
Sbjct: 173 KCENAYPGNITDTMVCASVQEGGKDSCQGDSGGPLVCNQSLQGIISWGQDPCAITRKPGV 232
Query: 239 YTKVCHYLEWIRETMKRN 256
YTKVC Y++WI+ETMK N
Sbjct: 233 YTKVCKYVDWIQETMKNN 250
>gi|20302147 kallikrein-related peptidase 15 isoform 3 preproprotein
[Homo sapiens]
Length = 171
Score = 253 bits (646), Expect = 1e-67
Identities = 121/121 (100%), Positives = 121/121 (100%)
Query: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA
Sbjct: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
Query: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP
Sbjct: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNP 120
Query: 121 Q 121
Q
Sbjct: 121 Q 121
Score = 115 bits (289), Expect = 3e-26
Identities = 50/51 (98%), Positives = 51/51 (100%)
Query: 206 EGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
+GDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN
Sbjct: 121 QGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 171
>gi|6005844 kallikrein 8 isoform 1 preproprotein [Homo sapiens]
Length = 260
Score = 248 bits (632), Expect = 5e-66
Identities = 121/254 (47%), Positives = 163/254 (64%), Gaps = 15/254 (5%)
Query: 1 MWLLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSA 60
M+LLL + AQ+ DK+L G EC PHSQPWQ AL++ + CG L+ +WVL+A
Sbjct: 13 MFLLLLGGAWAGHSRAQE-DKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTA 71
Query: 61 AHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY---EARSHRNDIMLLRLVQPAR 117
AHC+ VRLG+H+L+ +DGPEQ + IPHP Y + H +D+MLL+L A
Sbjct: 72 AHCKKPKYTVRLGDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQAS 131
Query: 118 LNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISD 177
L +V+P L C PG+ C VSGWG V+ SPR + PDTL+CA + I
Sbjct: 132 LGSKVKPISLADHCTQPGQKCTVSGWGTVT--------SPRE--NFPDTLNCAEVKIFPQ 181
Query: 178 TSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPG 237
C+ +YPG++T+ MVCAG+ +GA++C+GDSGGPLVC G LQGI SWG PC + KPG
Sbjct: 182 KKCEDAYPGQITDGMVCAGS-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPG 240
Query: 238 VYTKVCHYLEWIRE 251
VYT +C YL+WI++
Sbjct: 241 VYTNICRYLDWIKK 254
>gi|21464127 kallikrein 8 isoform 2 [Homo sapiens]
Length = 305
Score = 245 bits (626), Expect = 2e-65
Identities = 115/235 (48%), Positives = 154/235 (65%), Gaps = 14/235 (5%)
Query: 20 DKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79
DK+L G EC PHSQPWQ AL++ + CG L+ +WVL+AAHC+ VRLG+H+L+
Sbjct: 76 DKVLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQN 135
Query: 80 RDGPEQLRTTSRVIPHPRY---EARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
+DGPEQ + IPHP Y + H +D+MLL+L A L +V+P L C PG+
Sbjct: 136 KDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQPGQ 195
Query: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
C VSGWG V+ SPR + PDTL+CA + I C+ +YPG++T+ MVCAG
Sbjct: 196 KCTVSGWGTVT--------SPRE--NFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG 245
Query: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 251
+ +GA++C+GDSGGPLVC G LQGI SWG PC + KPGVYT +C YL+WI++
Sbjct: 246 S-SKGADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299
>gi|29366812 kallikrein-related peptidase 9 [Homo sapiens]
Length = 250
Score = 238 bits (607), Expect = 4e-63
Identities = 122/256 (47%), Positives = 160/256 (62%), Gaps = 15/256 (5%)
Query: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
LL L LLA D + + +EC P+SQPWQ L+ R CGA+LIS W+L+AAH
Sbjct: 5 LLCALLSLLAGHGWAD-TRAIGAEECRPNSQPWQAGLFHLTRLFCGATLISDRWLLTAAH 63
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYE----ARSHRNDIMLLRLVQPARL 118
C+ ++ VRLGEH+L K +GPEQL + PHP + A H +DIML+RL + ARL
Sbjct: 64 CRKPYLWVRLGEHHLWKWEGPEQLFRVTDFFPHPGFNKDLSANDHNDDIMLIRLPRQARL 123
Query: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
+P V+P L C PG C++SGWG VS SP++ P TL CANISI+ +
Sbjct: 124 SPAVQPLNLSQTCVSPGMQCLISGWGAVS--------SPKAL--FPVTLQCANISILENK 173
Query: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
C +YPG ++++M+CAG G SC+GDSGGPLVC G L G+VS G PC +P V
Sbjct: 174 LCHWAYPGHISDSMLCAGLWEGGRGSCQGDSGGPLVCNGTLAGVVSGGAEPCSRPRRPAV 233
Query: 239 YTKVCHYLEWIRETMK 254
YT VCHYL+WI+E M+
Sbjct: 234 YTSVCHYLDWIQEIME 249
>gi|61744424 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 234 bits (597), Expect = 5e-62
Identities = 109/251 (43%), Positives = 158/251 (62%), Gaps = 12/251 (4%)
Query: 4 LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC 63
L+ + L+A+ A++ +KL+ G C S P+Q ALY G CG LI P WVL+AAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 64 QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVR 123
+ ++V LG+HNLR+R+ ++ + R + HP Y+A SH DIMLLRL +PA+L+ ++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123
Query: 124 PAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS 183
P L C +C + GWG + + PDT+ CA I ++S C+ +
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD------------FPDTIQCAYIHLVSREECEHA 171
Query: 184 YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVC 243
YPG++T M+CAG E G +SC+GDSGGPLVCG L+G+VSWG++PC + KPGVYT VC
Sbjct: 172 YPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231
Query: 244 HYLEWIRETMK 254
Y WI++T++
Sbjct: 232 RYTNWIQKTIQ 242
>gi|4506155 kallikrein-related peptidase 6 isoform A preproprotein
[Homo sapiens]
Length = 244
Score = 234 bits (597), Expect = 5e-62
Identities = 109/251 (43%), Positives = 158/251 (62%), Gaps = 12/251 (4%)
Query: 4 LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHC 63
L+ + L+A+ A++ +KL+ G C S P+Q ALY G CG LI P WVL+AAHC
Sbjct: 4 LMVVLSLIAAAWAEEQNKLVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHC 63
Query: 64 QSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVR 123
+ ++V LG+HNLR+R+ ++ + R + HP Y+A SH DIMLLRL +PA+L+ ++
Sbjct: 64 KKPNLQVFLGKHNLRQRESSQEQSSVVRAVIHPDYDAASHDQDIMLLRLARPAKLSELIQ 123
Query: 124 PAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKS 183
P L C +C + GWG + + PDT+ CA I ++S C+ +
Sbjct: 124 PLPLERDCSANTTSCHILGWGKTADGD------------FPDTIQCAYIHLVSREECEHA 171
Query: 184 YPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVC 243
YPG++T M+CAG E G +SC+GDSGGPLVCG L+G+VSWG++PC + KPGVYT VC
Sbjct: 172 YPGQITQNMLCAGDEKYGKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVC 231
Query: 244 HYLEWIRETMK 254
Y WI++T++
Sbjct: 232 RYTNWIQKTIQ 242
>gi|91823048 kallikrein 14 preproprotein [Homo sapiens]
Length = 267
Score = 231 bits (588), Expect = 6e-61
Identities = 121/259 (46%), Positives = 157/259 (60%), Gaps = 15/259 (5%)
Query: 1 MWLLLTLSFLLASTAAQ---DGDKLLEGDECAPHSQPWQVALYE--RGRFNCGASLISPH 55
M+LLLT +LA Q D +K++ G C SQPWQ AL R RF CG +L+S
Sbjct: 17 MFLLLTALQVLAIAMTQSQEDENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQ 76
Query: 56 WVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQP 115
WV++AAHC ++V LG+HNLR+ + +Q+ R + HP Y +R+H ND+MLL+L QP
Sbjct: 77 WVITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQP 136
Query: 116 ARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISII 175
AR+ VRP + C PG +C VSGWG +S SP ++ P +L C NI+I
Sbjct: 137 ARIGRAVRPIEVTQACASPGTSCRVSGWGTIS--------SPIAR--YPASLQCVNINIS 186
Query: 176 SDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTK 235
D C K+YP +T MVCAG G +SC+GDSGGPLVC G LQG+VSWG C
Sbjct: 187 PDEVCQKAYPRTITPGMVCAGVPQGGKDSCQGDSGGPLVCRGQLQGLVSWGMERCALPGY 246
Query: 236 PGVYTKVCHYLEWIRETMK 254
PGVYT +C Y WI ETM+
Sbjct: 247 PGVYTNLCKYRSWIEETMR 265
>gi|22208987 kallikrein 12 isoform 2 [Homo sapiens]
Length = 248
Score = 229 bits (585), Expect = 1e-60
Identities = 121/257 (47%), Positives = 153/257 (59%), Gaps = 16/257 (6%)
Query: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
+ L L L S AA K+ G EC +SQPWQV L+E CG LI WVL+AAH
Sbjct: 5 IFLLLCVLGLSQAATP--KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY--EARSHRNDIMLLRLVQPARLNP 120
C VRLGEH+L + D EQ+R + + HP Y + SH +D+ LLRL P R+
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
Query: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180
V+P LP C G C VSGWG+ +H PR+ PD L C N+SI+S +C
Sbjct: 123 SVQPLPLPNDCATAGTECHVSGWGITNH--------PRN--PFPDLLQCLNLSIVSHATC 172
Query: 181 DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDV-PCDNTTKPGVY 239
YPGR+T+ MVCAG G ++C+GDSGGPLVCGG+LQG+VSWG V PC PGVY
Sbjct: 173 HGVYPGRITSNMVCAGGV-PGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVY 231
Query: 240 TKVCHYLEWIRETMKRN 256
T +C Y++WIR M+ N
Sbjct: 232 TYICKYVDWIRMIMRNN 248
>gi|11496281 kallikrein 13 precursor [Homo sapiens]
Length = 277
Score = 223 bits (569), Expect = 1e-58
Identities = 120/274 (43%), Positives = 157/274 (57%), Gaps = 29/274 (10%)
Query: 1 MW----LLLTLSFLLASTAAQDGDKLLE----------GDECAPHSQPWQVALYERGRFN 46
MW ++ +L+ L+ +Q+ K+L G C PHSQPWQ AL +GR
Sbjct: 1 MWPLALVIASLTLALSGGVSQESSKVLNTNGTSGFLPGGYTCFPHSQPWQAALLVQGRLL 60
Query: 47 CGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEAR----S 102
CG L+ P WVL+AAHC ++V LG+H L + + EQ+R IPHP Y +
Sbjct: 61 CGGVLVHPKWVLTAAHCLKEGLKVYLGKHALGRVEAGEQVREVVHSIPHPEYRRSPTHLN 120
Query: 103 HRNDIMLLRLVQPARLNPQVRPAVLP-TRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQV 161
H +DIMLL L P +L ++ L PG C VSGWG T SP QV
Sbjct: 121 HDHDIMLLELQSPVQLTGYIQTLPLSHNNRLTPGTTCRVSGWG--------TTTSP--QV 170
Query: 162 SLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQG 221
+ P TL CANI + SD C + YPG++T+ M+CAG + G +SCEGDSGGPLVC L G
Sbjct: 171 NYPKTLQCANIQLRSDEECRQVYPGKITDNMLCAGTKEGGKDSCEGDSGGPLVCNRTLYG 230
Query: 222 IVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKR 255
IVSWGD PC +PGVYT+V Y+ WIRET+++
Sbjct: 231 IVSWGDFPCGQPDRPGVYTRVSRYVLWIRETIRK 264
>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
Length = 247
Score = 219 bits (558), Expect = 2e-57
Identities = 111/255 (43%), Positives = 155/255 (60%), Gaps = 14/255 (5%)
Query: 4 LLTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAA 61
LL L+F+ A+ AA D DK++ G C +S P+QV+L G CG SLI+ WV+SA
Sbjct: 4 LLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSL-NSGYHFCGGSLINEQWVVSAG 62
Query: 62 HCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQ 121
HC ++VRLGEHN+ +G EQ +++I HP+Y+ ++ NDIML++L A +N +
Sbjct: 63 HCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINAR 122
Query: 122 VRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCD 181
V LPT P G C++SGWG + S PD L C + ++S C+
Sbjct: 123 VSTISLPTAPPATGTKCLISGWG----------NTASSGADYPDELQCLDAPVLSQAKCE 172
Query: 182 KSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTK 241
SYPG++T+ M C G G +SC+GDSGGP+VC G LQG+VSWGD C KPGVYTK
Sbjct: 173 ASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTK 231
Query: 242 VCHYLEWIRETMKRN 256
V +Y++WI+ T+ N
Sbjct: 232 VYNYVKWIKNTIAAN 246
>gi|117306176 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 218 bits (556), Expect = 3e-57
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 13/238 (5%)
Query: 21 KLLEGDECAPHSQPWQVALYER-GRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79
+++ G +C H+QPWQ AL R + CGA L+ P W+L+AAHC+ + RVRLG ++L
Sbjct: 66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSP 125
Query: 80 -RDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEAC 138
+ +Q+ + IPHP Y H ND+ML++L + R VRP + + CP G C
Sbjct: 126 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC 185
Query: 139 VVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAE 198
+VSGWG T SP QV P L C NIS++S C+ +YP ++ +TM CAG +
Sbjct: 186 LVSGWG--------TTKSP--QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDK 235
Query: 199 GRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
G +SC+GDSGGP+VC G LQG+VSWGD PC +PGVYT +C + +WI+ET++ N
Sbjct: 236 A-GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|117306172 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 218 bits (556), Expect = 3e-57
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 13/238 (5%)
Query: 21 KLLEGDECAPHSQPWQVALYER-GRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79
+++ G +C H+QPWQ AL R + CGA L+ P W+L+AAHC+ + RVRLG ++L
Sbjct: 66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSP 125
Query: 80 -RDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEAC 138
+ +Q+ + IPHP Y H ND+ML++L + R VRP + + CP G C
Sbjct: 126 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC 185
Query: 139 VVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAE 198
+VSGWG T SP QV P L C NIS++S C+ +YP ++ +TM CAG +
Sbjct: 186 LVSGWG--------TTKSP--QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDK 235
Query: 199 GRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
G +SC+GDSGGP+VC G LQG+VSWGD PC +PGVYT +C + +WI+ET++ N
Sbjct: 236 A-GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|6912644 kallikrein-related peptidase 5 preproprotein [Homo
sapiens]
Length = 293
Score = 218 bits (556), Expect = 3e-57
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 13/238 (5%)
Query: 21 KLLEGDECAPHSQPWQVALYER-GRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRK 79
+++ G +C H+QPWQ AL R + CGA L+ P W+L+AAHC+ + RVRLG ++L
Sbjct: 66 RIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSP 125
Query: 80 -RDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEAC 138
+ +Q+ + IPHP Y H ND+ML++L + R VRP + + CP G C
Sbjct: 126 VYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKC 185
Query: 139 VVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGAE 198
+VSGWG T SP QV P L C NIS++S C+ +YP ++ +TM CAG +
Sbjct: 186 LVSGWG--------TTKSP--QVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDK 235
Query: 199 GRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
G +SC+GDSGGP+VC G LQG+VSWGD PC +PGVYT +C + +WI+ET++ N
Sbjct: 236 A-GRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQAN 292
>gi|21327705 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 216 bits (550), Expect = 2e-56
Identities = 112/254 (44%), Positives = 146/254 (57%), Gaps = 13/254 (5%)
Query: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
LLL+L+ A AQ GDK+++G CA S PWQVAL + +CG L++ WVL+AAH
Sbjct: 12 LLLSLALETAGEEAQ-GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122
C+ V LG L R Q S+ HP Y ++H ND+ML++L ARL+ V
Sbjct: 71 CKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
Query: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182
+ LP+RC PG C VSGWG T SP V+ P L C ++ +IS C K
Sbjct: 129 KKVRLPSRCEPPGTTCTVSGWG--------TTTSP--DVTFPSDLMCVDVKLISPQDCTK 178
Query: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242
Y L N+M+CAG +C GDSGGPLVC G LQG+VSWG PC PGVYT+V
Sbjct: 179 VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQV 238
Query: 243 CHYLEWIRETMKRN 256
C + +WI +TMK++
Sbjct: 239 CKFTKWINDTMKKH 252
>gi|4826950 stratum corneum chymotryptic enzyme preproprotein [Homo
sapiens]
Length = 253
Score = 216 bits (550), Expect = 2e-56
Identities = 112/254 (44%), Positives = 146/254 (57%), Gaps = 13/254 (5%)
Query: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
LLL+L+ A AQ GDK+++G CA S PWQVAL + +CG L++ WVL+AAH
Sbjct: 12 LLLSLALETAGEEAQ-GDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAH 70
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122
C+ V LG L R Q S+ HP Y ++H ND+ML++L ARL+ V
Sbjct: 71 CKMNEYTVHLGSDTLGDRRA--QRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMV 128
Query: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182
+ LP+RC PG C VSGWG T SP V+ P L C ++ +IS C K
Sbjct: 129 KKVRLPSRCEPPGTTCTVSGWG--------TTTSP--DVTFPSDLMCVDVKLISPQDCTK 178
Query: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242
Y L N+M+CAG +C GDSGGPLVC G LQG+VSWG PC PGVYT+V
Sbjct: 179 VYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQV 238
Query: 243 CHYLEWIRETMKRN 256
C + +WI +TMK++
Sbjct: 239 CKFTKWINDTMKKH 252
>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
Length = 247
Score = 216 bits (549), Expect = 2e-56
Identities = 113/258 (43%), Positives = 156/258 (60%), Gaps = 14/258 (5%)
Query: 1 MWLLLTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVL 58
M LLL L+F+ A+ AA D DK++ G C +S P+QV+L F CG SLIS WV+
Sbjct: 1 MNLLLILTFVAAAVAAPFDDDDKIVGGYICEENSVPYQVSLNSGYHF-CGGSLISEQWVV 59
Query: 59 SAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARL 118
SA HC ++VRLGEHN+ +G EQ +++I HP+Y +R+ NDI+L++L PA +
Sbjct: 60 SAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVI 119
Query: 119 NPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDT 178
N +V LPT P G ++SGWG + S PD L C + ++S
Sbjct: 120 NSRVSAISLPTAPPAAGTESLISGWG----------NTLSSGADYPDELQCLDAPVLSQA 169
Query: 179 SCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGV 238
C+ SYPG++TN M C G G +SC+GDSGGP+V G LQGIVSWG C +PGV
Sbjct: 170 ECEASYPGKITNNMFCVGFLEGGKDSCQGDSGGPVVSNGELQGIVSWG-YGCAQKNRPGV 228
Query: 239 YTKVCHYLEWIRETMKRN 256
YTKV +Y++WI++T+ N
Sbjct: 229 YTKVYNYVDWIKDTIAAN 246
>gi|9665236 kallikrein 12 isoform 1 [Homo sapiens]
Length = 254
Score = 215 bits (547), Expect = 3e-56
Identities = 115/245 (46%), Positives = 145/245 (59%), Gaps = 16/245 (6%)
Query: 3 LLLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
+ L L L S AA K+ G EC +SQPWQV L+E CG LI WVL+AAH
Sbjct: 5 IFLLLCVLGLSQAATP--KIFNGTECGRNSQPWQVGLFEGTSLRCGGVLIDHRWVLTAAH 62
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY--EARSHRNDIMLLRLVQPARLNP 120
C VRLGEH+L + D EQ+R + + HP Y + SH +D+ LLRL P R+
Sbjct: 63 CSGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTS 122
Query: 121 QVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSC 180
V+P LP C G C VSGWG+ +H PR+ PD L C N+SI+S +C
Sbjct: 123 SVQPLPLPNDCATAGTECHVSGWGITNH--------PRN--PFPDLLQCLNLSIVSHATC 172
Query: 181 DKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDV-PCDNTTKPGVY 239
YPGR+T+ MVCAG G ++C+GDSGGPLVCGG+LQG+VSWG V PC PGVY
Sbjct: 173 HGVYPGRITSNMVCAGGV-PGQDACQGDSGGPLVCGGVLQGLVSWGSVGPCGQDGIPGVY 231
Query: 240 TKVCH 244
T +C+
Sbjct: 232 TYICN 236
>gi|21536452 mesotrypsin isoform 2 preproprotein [Homo sapiens]
Length = 247
Score = 209 bits (533), Expect = 1e-54
Identities = 108/254 (42%), Positives = 152/254 (59%), Gaps = 14/254 (5%)
Query: 5 LTLSFLLASTAA--QDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAH 62
L L+F+ A+ A D DK++ G C +S P+QV+L F CG SLIS WV+SAAH
Sbjct: 5 LILAFVGAAVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAH 63
Query: 63 CQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQV 122
C ++VRLGEHN++ +G EQ +++I HP+Y + NDIML++L PA +N +V
Sbjct: 64 CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV 123
Query: 123 RPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDK 182
LPT P G C++SGWG + PD L C + +++ C
Sbjct: 124 STISLPTAPPAAGTECLISGWG----------NTLSFGADYPDELKCLDAPVLTQAECKA 173
Query: 183 SYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKV 242
SYPG++TN+M C G G +SC+ DSGGP+VC G LQG+VSWG C +PGVYTKV
Sbjct: 174 SYPGKITNSMFCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKV 232
Query: 243 CHYLEWIRETMKRN 256
+Y++WI++T+ N
Sbjct: 233 YNYVDWIKDTIAAN 246
>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
Length = 304
Score = 207 bits (526), Expect = 9e-54
Identities = 103/239 (43%), Positives = 144/239 (60%), Gaps = 12/239 (5%)
Query: 18 DGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNL 77
D DK++ G C +S P+QV+L F CG SLIS WV+SAAHC ++VRLGEHN+
Sbjct: 77 DDDKIVGGYTCEENSLPYQVSLNSGSHF-CGGSLISEQWVVSAAHCYKTRIQVRLGEHNI 135
Query: 78 RKRDGPEQLRTTSRVIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEA 137
+ +G EQ +++I HP+Y + NDIML++L PA +N +V LPT P G
Sbjct: 136 KVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTAPPAAGTE 195
Query: 138 CVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAGA 197
C++SGWG + PD L C + +++ C SYPG++TN+M C G
Sbjct: 196 CLISGWG----------NTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGF 245
Query: 198 EGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
G +SC+ DSGGP+VC G LQG+VSWG C +PGVYTKV +Y++WI++T+ N
Sbjct: 246 LEGGKDSCQRDSGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAAN 303
>gi|5031829 kallikrein 2, prostatic isoform 1 [Homo sapiens]
Length = 261
Score = 205 bits (521), Expect = 4e-53
Identities = 113/272 (41%), Positives = 153/272 (56%), Gaps = 28/272 (10%)
Query: 1 MW-LLLTLSFLLASTAAQD--GDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
MW L+L+++ + T A +++ G EC HSQPWQVA+Y G +CG L+ P WV
Sbjct: 1 MWDLVLSIALSVGCTGAVPLIQSRIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWV 60
Query: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRY-------------EARSHR 104
L+AAHC + +V LG HNL + + Q S PHP Y E SH
Sbjct: 61 LTAAHCLKKNSQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSH- 119
Query: 105 NDIMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLP 164
D+MLLRL +PA++ V+ LPT+ P G C SGWG + EP PRS
Sbjct: 120 -DLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCYASGWGSI---EPEEFLRPRS----- 170
Query: 165 DTLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVS 224
L C ++ ++S+ C ++Y ++T M+CAG G ++C GDSGGPLVC G+LQGI S
Sbjct: 171 --LQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGPLVCNGVLQGITS 228
Query: 225 WGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
WG PC KP VYTKV HY +WI++T+ N
Sbjct: 229 WGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 260
>gi|117422433 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 201 bits (512), Expect = 4e-52
Identities = 100/240 (41%), Positives = 142/240 (59%), Gaps = 20/240 (8%)
Query: 25 GDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPE 84
G CA SQPWQV+L+ F+C L+ WVL+AAHC ++ + R+G+ +L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QLRTTSRVIPHPRYEA--------RSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
QLR T+R + HP+Y R+ +D+MLL+L +P L P+VR LP RC PG+
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
C V+GWG + +V L C++I+I+S C+ YPG +TN M+CAG
Sbjct: 168 QCQVAGWGTTAAR----------RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG 217
Query: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
+ RG + C+ DSGGPLVC LQGI+SWG PC + P VYT++C Y+ WI + ++ N
Sbjct: 218 LD-RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208984 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 201 bits (512), Expect = 4e-52
Identities = 100/240 (41%), Positives = 142/240 (59%), Gaps = 20/240 (8%)
Query: 25 GDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPE 84
G CA SQPWQV+L+ F+C L+ WVL+AAHC ++ + R+G+ +L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QLRTTSRVIPHPRYEA--------RSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
QLR T+R + HP+Y R+ +D+MLL+L +P L P+VR LP RC PG+
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
C V+GWG + +V L C++I+I+S C+ YPG +TN M+CAG
Sbjct: 168 QCQVAGWGTTAAR----------RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG 217
Query: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
+ RG + C+ DSGGPLVC LQGI+SWG PC + P VYT++C Y+ WI + ++ N
Sbjct: 218 LD-RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|22208982 kallikrein-related peptidase 10 preproprotein [Homo
sapiens]
Length = 276
Score = 201 bits (512), Expect = 4e-52
Identities = 100/240 (41%), Positives = 142/240 (59%), Gaps = 20/240 (8%)
Query: 25 GDECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPE 84
G CA SQPWQV+L+ F+C L+ WVL+AAHC ++ + R+G+ +L G E
Sbjct: 49 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQG-E 107
Query: 85 QLRTTSRVIPHPRYEA--------RSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHPGE 136
QLR T+R + HP+Y R+ +D+MLL+L +P L P+VR LP RC PG+
Sbjct: 108 QLRRTTRSVVHPKYHQGSGPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQPGD 167
Query: 137 ACVVSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSYPGRLTNTMVCAG 196
C V+GWG + +V L C++I+I+S C+ YPG +TN M+CAG
Sbjct: 168 QCQVAGWGTTAAR----------RVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG 217
Query: 197 AEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
+ RG + C+ DSGGPLVC LQGI+SWG PC + P VYT++C Y+ WI + ++ N
Sbjct: 218 LD-RGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 276
>gi|4502173 prostate specific antigen isoform 1 preproprotein [Homo
sapiens]
Length = 261
Score = 199 bits (505), Expect = 3e-51
Identities = 108/270 (40%), Positives = 143/270 (52%), Gaps = 24/270 (8%)
Query: 1 MWL---LLTLSFLLASTAAQDGDKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
MW+ LTLS A +++ G EC HSQPWQV + RGR CG L+ P WV
Sbjct: 1 MWVPVVFLTLSVTWIGAAPLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWV 60
Query: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHPRYEARSHRN-----------D 106
L+AAHC + LG H+L + Q+ S PHP Y+ +N D
Sbjct: 61 LTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHD 120
Query: 107 IMLLRLVQPARLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPDT 166
+MLLRL +PA L V+ LPT+ P G C SGWG + E T P
Sbjct: 121 LMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLT----------PKK 170
Query: 167 LHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWG 226
L C ++ +IS+ C + +P ++T M+CAG G +C GDSGGPLVC G+LQGI SWG
Sbjct: 171 LQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWG 230
Query: 227 DVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
PC +P +YTKV HY +WI++T+ N
Sbjct: 231 SEPCALPERPSLYTKVVHYRKWIKDTIVAN 260
>gi|4504875 kallikrein 1 preproprotein [Homo sapiens]
Length = 262
Score = 192 bits (489), Expect = 2e-49
Identities = 105/271 (38%), Positives = 143/271 (52%), Gaps = 25/271 (9%)
Query: 1 MW-LLLTLSFLLASTAAQDG--DKLLEGDECAPHSQPWQVALYERGRFNCGASLISPHWV 57
MW L+L L+ L T A +++ G EC HSQPWQ ALY F CG L+ WV
Sbjct: 1 MWFLVLCLALSLGGTGAAPPIQSRIVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWV 60
Query: 58 LSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTTSRVIPHP-----------RYEARSHRND 106
L+AAHC S ++ LG HNL + Q S PHP R + +D
Sbjct: 61 LTAAHCISDNYQLWLGRHNLFDDENTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHD 120
Query: 107 IMLLRLVQPA-RLNPQVRPAVLPTRCPHPGEACVVSGWGLVSHNEPGTAGSPRSQVSLPD 165
+MLLRL +PA + V+ LPT P G C+ SGWG + EP S PD
Sbjct: 121 LMLLRLTEPADTITDAVKVVELPTEEPEVGSTCLASGWGSI---EP-------ENFSFPD 170
Query: 166 TLHCANISIISDTSCDKSYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSW 225
L C ++ I+ + C K++ ++T+ M+C G G ++C GDSGGPL+C G+LQG+ SW
Sbjct: 171 DLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGPLMCDGVLQGVTSW 230
Query: 226 GDVPCDNTTKPGVYTKVCHYLEWIRETMKRN 256
G VPC KP V +V Y++WI +T+ N
Sbjct: 231 GYVPCGTPNKPSVAVRVLSYVKWIEDTIAEN 261
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,589,371
Number of Sequences: 37866
Number of extensions: 591711
Number of successful extensions: 1992
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1278
Number of HSP's gapped (non-prelim): 248
length of query: 256
length of database: 18,247,518
effective HSP length: 100
effective length of query: 156
effective length of database: 14,460,918
effective search space: 2255903208
effective search space used: 2255903208
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.