Search of human proteins with 197333811

Search of human proteins with 197333811

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens]
         (1524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens]       2991   0.0  
gi|109826564 neurofibromin isoform 1 [Homo sapiens]                    32   3.6  
gi|4557793 neurofibromin isoform 2 [Homo sapiens]                      32   3.6  
gi|94681049 hypothetical protein LOC80217 [Homo sapiens]               32   3.6  
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H...    32   4.7  
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            32   6.1  
gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]            31   8.0  

>gi|197333811 URB2 ribosome biogenesis 2 homolog [Homo sapiens]
          Length = 1524

 Score = 2991 bits (7755), Expect = 0.0
 Identities = 1524/1524 (100%), Positives = 1524/1524 (100%)

Query: 1    MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKL 60
            MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKL
Sbjct: 1    MAAVYSGISLKLKSKTTSWEDKLKLAHFAWISHQCFLPNKEQVLLDWARQSLVAFYKKKL 60

Query: 61   ELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNIC 120
            ELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNIC
Sbjct: 61   ELKEDIVERLWIYIDNILHSRKLQNLLKNGKTINLQISLVKIINERVAEFSLSGSQRNIC 120

Query: 121  AVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQPEGAVVAQLFEVIHLALGHY 180
            AVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQPEGAVVAQLFEVIHLALGHY
Sbjct: 121  AVLRCCQGILSTPALAVIYTAKQELMVALLSQLCWSACRQPEGAVVAQLFEVIHLALGHY 180

Query: 181  LLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAM 240
            LLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAM
Sbjct: 181  LLILQQQVNPRRAFGDVTAHLLQPCLVLRHLLSGGTWTQAGQGQLRQVLSRDIRSQIEAM 240

Query: 241  FRGGIFQPELLSSYKEGLLDQQQGDVKTGAMKNLLAPMDTVLNRLVDAGYCAASLHTSVV 300
            FRGGIFQPELLSSYKEGLLDQQQGDVKTGAMKNLLAPMDTVLNRLVDAGYCAASLHTSVV
Sbjct: 241  FRGGIFQPELLSSYKEGLLDQQQGDVKTGAMKNLLAPMDTVLNRLVDAGYCAASLHTSVV 300

Query: 301  ANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVV 360
            ANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVV
Sbjct: 301  ANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALSTSDWTTELLVV 360

Query: 361  EQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNH 420
            EQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNH
Sbjct: 361  EQLLNSVANNNIYNIAADRIRHEEAQFRFYRHVAELLINHAQAPIPAWFRCLKTLISLNH 420

Query: 421  LILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRP 480
            LILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRP
Sbjct: 421  LILEPDLDDLLASAWIDAEVTEFRTKKAQEALIRTVFQTYAKLRQVPRLFEEVLGVICRP 480

Query: 481  AAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMALKSL 540
            AAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMALKSL
Sbjct: 481  AAEALRQPVLASGPSTVLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMALKSL 540

Query: 541  SLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQ 600
            SLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQ
Sbjct: 541  SLSLLLHCIMFNMRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWLQ 600

Query: 601  KVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIE 660
            KVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIE
Sbjct: 601  KVSDSVLLLSYTWAQVDAMFSLNCSQYHSMSGPLIGVALEISNLPSLLPGVKTQHWKKIE 660

Query: 661  KFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTT 720
            KFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTT
Sbjct: 661  KFTAQFSSLGTYCLEQLYLQKMKRTLMQTSFRSEGAIQSLRCDAAFIIGSGRKSLNQRTT 720

Query: 721  ASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSI 780
            ASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSI
Sbjct: 721  ASWDGQVGMVSGLTYPVAHWHLIVSNLTILISYLCPDDVGYLASVLLRTLPMGKAQEVSI 780

Query: 781  DEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPW 840
            DEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPW
Sbjct: 781  DEEAYITLEKISKAFLHSPLFPEMQSLHSAFLTCVTTSCSSILCSGAQRDSGLVSQQLPW 840

Query: 841  LFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEV 900
            LFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEV
Sbjct: 841  LFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLESILGLLEV 900

Query: 901  ISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSSLALKFLTTCYQLLGYLQKGKSARS 960
            ISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSSLALKFLTTCYQLLGYLQKGKSARS
Sbjct: 901  ISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSSLALKFLTTCYQLLGYLQKGKSARS 960

Query: 961  VFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLEFLQVIGTFLEELMQMLIQMKLSLV 1020
            VFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLEFLQVIGTFLEELMQMLIQMKLSLV
Sbjct: 961  VFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLEFLQVIGTFLEELMQMLIQMKLSLV 1020

Query: 1021 LNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEA 1080
            LNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEA
Sbjct: 1021 LNFRKITAFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEA 1080

Query: 1081 PAALSELLQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADIS 1140
            PAALSELLQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADIS
Sbjct: 1081 PAALSELLQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADIS 1140

Query: 1141 QGSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKKDSVFT 1200
            QGSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKKDSVFT
Sbjct: 1141 QGSDRTLLSHVALYQGVYSQILLELPALAGHDQSFQAALQFLTLFFLAPELHPKKDSVFT 1200

Query: 1201 SMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMW 1260
            SMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMW
Sbjct: 1201 SMFHSVRRVLADPEIPVQVTQDIEPHLGALFTQMLEVGTTEDLRLVMQCILQGLDVSNMW 1260

Query: 1261 KADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVG 1320
            KADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVG
Sbjct: 1261 KADVQAVVSAVTLLRLLLNCPLSGEKASLLWRACPQIVTALTLLNREASQEQPVSLTVVG 1320

Query: 1321 PVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQC 1380
            PVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQC
Sbjct: 1321 PVLDVLAALLRQGEEAIGNPHHVSLAFSILLTVPLDHLKPLEYGSVFPRLHNVLFSILQC 1380

Query: 1381 HPKVMLKAIPSFLNSFNRLVFSVMREGRQKDKGSIDDLPTVLKCARLVERMYSHIAARAE 1440
            HPKVMLKAIPSFLNSFNRLVFSVMREGRQKDKGSIDDLPTVLKCARLVERMYSHIAARAE
Sbjct: 1381 HPKVMLKAIPSFLNSFNRLVFSVMREGRQKDKGSIDDLPTVLKCARLVERMYSHIAARAE 1440

Query: 1441 EFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDI 1500
            EFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDI
Sbjct: 1441 EFAVFSPFMVAQYVLEVQKVTLYPAVKSLLQEGIYLILDLCIEPDVQFLRASLQPGMRDI 1500

Query: 1501 FKELYNDYLKYHKAKHEGEKRYTA 1524
            FKELYNDYLKYHKAKHEGEKRYTA
Sbjct: 1501 FKELYNDYLKYHKAKHEGEKRYTA 1524


>gi|109826564 neurofibromin isoform 1 [Homo sapiens]
          Length = 2839

 Score = 32.3 bits (72), Expect = 3.6
 Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 497  VLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMAL----KSLSLSLLLHCIMFN 552
            ++ AC+ ++P  + LD W+ + ++F     P LQ  A +      K +S   +   I   
Sbjct: 2212 IMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRIL 2271

Query: 553  MRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWL 599
             ++L+S    P    +Q ++E  +  L +    L  D+P  +   W+
Sbjct: 2272 SKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWV 2318


>gi|4557793 neurofibromin isoform 2 [Homo sapiens]
          Length = 2818

 Score = 32.3 bits (72), Expect = 3.6
 Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 497  VLSACLLELPPSQILDTWSLVLEKFQSLVLPYLQSDADMAL----KSLSLSLLLHCIMFN 552
            ++ AC+ ++P  + LD W+ + ++F     P LQ  A +      K +S   +   I   
Sbjct: 2191 IMEACMRDIPTCKWLDQWTELAQRFAFQYNPSLQPRALVVFGCISKRVSHGQIKQIIRIL 2250

Query: 553  MRSLDSSTPLPIVRRTQCMMERMMRELVQPLLALLPDTPGPEPELWL 599
             ++L+S    P    +Q ++E  +  L +    L  D+P  +   W+
Sbjct: 2251 SKALESCLKGPDTYNSQVLIEATVIALTKLQPLLNKDSPLHKALFWV 2297


>gi|94681049 hypothetical protein LOC80217 [Homo sapiens]
          Length = 1665

 Score = 32.3 bits (72), Expect = 3.6
 Identities = 22/76 (28%), Positives = 37/76 (48%), Gaps = 7/76 (9%)

Query: 834 VSQQLPWLFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLVKSDFPIQLEGEQLES 893
           V +++PW+ +K    +    N F+K        R EI Q + SL K+   +  E ++LE+
Sbjct: 781 VKKEIPWIQQKSQEAIKKEVNLFSK-------KRKEIKQGIKSLSKTILNMMEENDKLEN 833

Query: 894 ILGLLEVISALQLDSL 909
           I  L +    L L+ L
Sbjct: 834 IAKLDQQEFGLDLEEL 849


>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
           sapiens]
          Length = 1453

 Score = 32.0 bits (71), Expect = 4.7
 Identities = 20/68 (29%), Positives = 33/68 (48%)

Query: 291 CAASLHTSVVANSVALLYKLFLDSYFKEGNQLLCFQVLPRLFGCLKISHLQEEQSKALST 350
           C +S  +S V NS A+L  ++LD    +GN+L  +    R +G    SH ++       +
Sbjct: 198 CPSSFISSGVVNSPAVLRPIWLDDILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS 257

Query: 351 SDWTTELL 358
           SD    L+
Sbjct: 258 SDLELRLV 265


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 31.6 bits (70), Expect = 6.1
 Identities = 29/122 (23%), Positives = 50/122 (40%), Gaps = 21/122 (17%)

Query: 1028 AFLSSSKPYTEAASSKQLENQNPQGRQLLLVSLTRLCHVLGPFLKEQKLGQEAPAALSEL 1087
            AFLS S+   EA  + +LE++N  GR      + R+ + L    +E +   +  AA    
Sbjct: 1088 AFLSYSQKIQEAVKALKLESENRNGRSPGTQEMLRMWYELD---EESRRKYQKKAA---- 1140

Query: 1088 LQQVVLQTGAVLQLCSVPGARGWRLPSVLISSVSTLLEADLGQHCRDGGADISQGSDRTL 1147
                          C  P    WR P +  +SVS   E  +  + ++  A   +  +++ 
Sbjct: 1141 -------------ACPDPSLSVWR-PDIYFASVSETFETKVDDYSQEWAAQTEKSYEKSE 1186

Query: 1148 LS 1149
            LS
Sbjct: 1187 LS 1188


>gi|67906814 Rho GTPase activating protein 19 [Homo sapiens]
          Length = 494

 Score = 31.2 bits (69), Expect = 8.0
 Identities = 46/200 (23%), Positives = 81/200 (40%), Gaps = 29/200 (14%)

Query: 819  CSSILCSGAQRDSGLVSQQLPWLFEKDHMVVGHWENRFAKAGPEGIEPRGEIAQNLLSLV 878
            CS ++C+    DS L  Q  P +F  D  V                + R E  +    LV
Sbjct: 23   CSFVICN----DSSLRGQ--PIIFNPDFFVE---------------KLRHEKPEIFTELV 61

Query: 879  KSDFP--IQLEGEQLESILGLLEVISALQLDSLLPPYHVHYFLVLLSMAVTKLGCSCSSS 936
             S+    I L G +L  ++G ++    L+L     P    +F  L+S+   + G    S 
Sbjct: 62   VSNITRLIDLPGTELAQLMGEVD----LKLPGGAGPAS-GFFRSLMSLKRKEKGVIFGSP 116

Query: 937  LALKFLTTCYQLLGYLQKGKSARSVFKIMYGSDIFEVVLTSLFRASSRFLIEMDDPAWLE 996
            L  + +   YQL+ YL K      +F++  G+ + + +L       +   +E  +    +
Sbjct: 117  LTEEGIAQIYQLIEYLHKNLRVEGLFRVP-GNSVRQQILRDALNNGTDIDLESGEFHSND 175

Query: 997  FLQVIGTFLEELMQMLIQMK 1016
               ++  FL EL + L+  K
Sbjct: 176  VATLLKMFLGELPEPLLTHK 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,480,896
Number of Sequences: 37866
Number of extensions: 2262328
Number of successful extensions: 6095
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 6081
Number of HSP's gapped (non-prelim): 17
length of query: 1524
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1409
effective length of database: 13,892,928
effective search space: 19575135552
effective search space used: 19575135552
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.