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Search of human proteins with 194018472
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo sapiens]
(406 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 794 0.0
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 336 2e-92
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 334 7e-92
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 332 5e-91
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 314 8e-86
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 314 8e-86
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 314 8e-86
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 314 8e-86
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 304 8e-83
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 302 3e-82
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 285 5e-77
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 278 6e-75
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 220 2e-57
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 202 3e-52
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 199 3e-51
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 194 2e-49
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 192 6e-49
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 190 2e-48
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 190 2e-48
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 189 3e-48
gi|8393956 serine (or cysteine) proteinase inhibitor, clade B (o... 187 1e-47
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 186 3e-47
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 186 3e-47
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 794 bits (2051), Expect = 0.0
Identities = 406/406 (100%), Positives = 406/406 (100%)
Query: 1 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAA 60
MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAA
Sbjct: 1 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASAA 60
Query: 61 PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQ 120
PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQ
Sbjct: 61 PSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQ 120
Query: 121 PRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQT 180
PRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQT
Sbjct: 121 PRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQT 180
Query: 181 KGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED 240
KGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED
Sbjct: 181 KGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRED 240
Query: 241 QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLE 300
QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLE
Sbjct: 241 QYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLE 300
Query: 301 LYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGT 360
LYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGT
Sbjct: 301 LYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGT 360
Query: 361 RAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP 406
RAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP
Sbjct: 361 RAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNILFLGKVNRP 406
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 336 bits (862), Expect = 2e-92
Identities = 189/420 (45%), Positives = 264/420 (62%), Gaps = 18/420 (4%)
Query: 4 FLLLCLV-LLSPQGASLHRHHPREMKKRVEDLHVGAT--------VAPSSRRDFTFDLYR 54
+LLL LV LL+ LH H E + T +AP++ DF F Y
Sbjct: 6 YLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANA-DFAFRFYY 64
Query: 55 ALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQL 114
+AS P ++IFFSP+SIS + AMLSLGA S ++ QILEGLG NL + SE ++HRGFQ L
Sbjct: 65 LIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHL 124
Query: 115 LQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQIND 174
L LN P G + +G+ALF + F++ +Y A F TNF D+ G ++ IND
Sbjct: 125 LHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLIND 184
Query: 175 YVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVP 234
+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T +DFYV T VRVP
Sbjct: 185 HVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVP 244
Query: 235 MMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKM 293
MM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++E L+ + L +W +
Sbjct: 245 MMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNL 304
Query: 294 FKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVH 349
+KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLSGI+ ++ S+ H
Sbjct: 305 LRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFH 364
Query: 350 KAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVD---NNILFLGKVNRP 406
KA ++VDE+GT AAAAT F SA+ N L FNRPFL+ I ++LFLGKV P
Sbjct: 365 KATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 334 bits (857), Expect = 7e-92
Identities = 186/378 (49%), Positives = 247/378 (65%), Gaps = 7/378 (1%)
Query: 35 HVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEG 94
HV +A S+ DF F LY+ L AP +++ FSP+SIS +LA LSLGA ++T +IL+G
Sbjct: 44 HVDLGLA-SANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKG 102
Query: 95 LGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYL 154
L NL ++SE E+H+ FQ LL+ LNQ D QLS+GNA+F + L D F K LY
Sbjct: 103 LKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYG 162
Query: 155 ADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFN 214
++ F T+F+DSA A K INDYV T+GKI DL+K+LDS ++++VNYIFFKAKWE F+
Sbjct: 163 SEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFD 222
Query: 215 HKGTQEQDFYVTSETVVRVPMMSRED-QYHYLLDRNLSCRVVGVPYQGNATALFILPSEG 273
+ T + FY++ + V VPMMS Y D LSC VV + Y GNA+ALFILP +
Sbjct: 223 PQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQD 282
Query: 274 KMQQVENGLSEKTLRKWLKMFKKRQL-ELYLPKFSIEGSYQLEKVLPSLGISNVFTSHAD 332
KM++VE L +TL++W + R++ ELYLPKFSI Y L +L LGI FTS AD
Sbjct: 283 KMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKAD 342
Query: 333 LSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMF 391
LSGI+ N+ VS++VHKAV++V E GT A+AAT T SA + ++ +V FNRPFLM
Sbjct: 343 LSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMI 402
Query: 392 IV---DNNILFLGKVNRP 406
IV NI F+ KV P
Sbjct: 403 IVPTDTQNIFFMSKVTNP 420
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 332 bits (850), Expect = 5e-91
Identities = 177/369 (47%), Positives = 243/369 (65%), Gaps = 5/369 (1%)
Query: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS 102
S DF F LYR L PSQ+IFFSPVS+S SLAMLSLGA S TK QIL+GLG NL +
Sbjct: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHT 123
Query: 103 SEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF 162
E +H+GFQ L+ L P L +G+ALF + LQ F+ +K LY A+ F T+F
Sbjct: 124 PESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDF 183
Query: 163 RDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ- 221
+ + A +IN +V K+T+GK+VD+++ LD +++VN+IFFKAKWE F+ + T++
Sbjct: 184 SNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNF 243
Query: 222 DFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENG 281
F V + V VPMM +++Q+ + +D L+C V+ + Y+G+A A F+LPS+GKM+Q+E
Sbjct: 244 PFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQA 303
Query: 282 LSEKTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSN 341
LS +TLRKW +KR +E+++P+FSI SY LE +LP +GI NVF +AD SGI+ +
Sbjct: 304 LSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDS 363
Query: 342 IQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNI 397
+QVS+ HKAV++V E GT A AAT T F RS S V FNR FLM I + + I
Sbjct: 364 LQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGI 423
Query: 398 LFLGKVNRP 406
LFLGKV P
Sbjct: 424 LFLGKVENP 432
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 314 bits (805), Expect = 8e-86
Identities = 180/412 (43%), Positives = 249/412 (60%), Gaps = 22/412 (5%)
Query: 6 LLCLVLLS----PQGASLHR----HHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALA 57
L CLV +S PQG + + HH ++ H + +F F LYR LA
Sbjct: 15 LCCLVPVSLAEDPQGDAAQKTDTSHHDQD--------HPTFNKITPNLAEFAFSLYRQLA 66
Query: 58 SAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQE 117
+ S +IFFSPVSI+ + AMLSLG + T +ILEGL NL + E ++H GFQ+LL+
Sbjct: 67 HQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRT 126
Query: 118 LNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVA 177
LNQP QL+ GN LF + L D F+ +K LY ++ F NF D+ A KQINDYV
Sbjct: 127 LNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVE 186
Query: 178 KQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMS 237
K T+GKIVDL+K LD + V +VNYIFFK KWE F K T+E+DF+V T V+VPMM
Sbjct: 187 KGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMK 246
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
R ++ + LS V+ + Y GNATA+F LP EGK+Q +EN L+ + K+L+ +R
Sbjct: 247 RLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLENEDRR 306
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
L+LPK SI G+Y L+ VL LGI+ VF++ ADLSG++ + +++S+ VHKAV+ +DE
Sbjct: 307 SASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDE 366
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNNI---LFLGKVNRP 406
GT AA G +F + FN+PF+ +++ N LF+GKV P
Sbjct: 367 KGTEAA---GAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 304 bits (779), Expect = 8e-83
Identities = 168/415 (40%), Positives = 255/415 (61%), Gaps = 12/415 (2%)
Query: 3 LFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSSRR------DFTFDLYRAL 56
L+LL +L S L H + ++ H + AP+ R +F LY+ L
Sbjct: 6 LWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKEL 65
Query: 57 ASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQ 116
A+ AP +IFFSPVSIS +LA+LSLGA ++T ILEGLG NL ++ E ++H+GF+ LL
Sbjct: 66 AADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLH 124
Query: 117 ELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYV 176
L P +L +GN+LF D + + ++ ++K LY A F NF DS +QINDY+
Sbjct: 125 TLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYL 184
Query: 177 AKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQD-FYVTSETVVRVPM 235
+QT G++VD L + +++ NYIFFKAKW+ F+ TQ+Q+ F+V T ++VPM
Sbjct: 185 RRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPM 244
Query: 236 MSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFK 295
M +++ + +L D++L+C V+ + Y+GNA AL +LP GKM+QVE L +TLRKW ++
Sbjct: 245 MHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKWGQLLL 304
Query: 296 KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEV 355
L+L+LP+FSI G+Y LE +LP +G++N+ AD SG++ N +S++ HKA+V++
Sbjct: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364
Query: 356 DESGTRAAAATGTIFTFRSAR-LNSQRLVFNRPFLMF---IVDNNILFLGKVNRP 406
E GT A AA+G + S ++ FNRPFL+ + ++LFLGKV P
Sbjct: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 302 bits (774), Expect = 3e-82
Identities = 167/410 (40%), Positives = 246/410 (60%), Gaps = 10/410 (2%)
Query: 1 MQLFLLLCLVLLSPQGA-SLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASA 59
M L L CL+ L G ++ P + + H G S+ DF F LY+ L +
Sbjct: 1 MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLA---SANVDFAFSLYKHLVAL 57
Query: 60 APSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELN 119
+P ++IF SPVSISM+LAMLSLG T+ Q+L+GLG NL + SE E+H+GFQ L Q
Sbjct: 58 SPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFA 117
Query: 120 QPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQ 179
+ ++++GNALF D ++L ++F + +K Y ++ NF+D A A +QIN YV +
Sbjct: 118 KSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNK 177
Query: 180 TKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRE 239
T+GKIVDL LDS A++++VNYIFFK W F+ T+E++FYV TVV+VPMM +
Sbjct: 178 TQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQS 237
Query: 240 DQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQL 299
YL D L C++V + Y GN T FILP +GKM V LS T+ +W Q+
Sbjct: 238 STISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQV 297
Query: 300 ELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESG 359
+LY+PK +I G Y L VL +GI+++FT+ A+ S I+ + ++ S++VHKAV++++E G
Sbjct: 298 DLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEG 357
Query: 360 TRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN---NILFLGKVNRP 406
A +TG S + L FN+PF++ I D+ + LFL +V P
Sbjct: 358 VDTAGSTGVTLNLTSKPI---ILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 285 bits (729), Expect = 5e-77
Identities = 158/413 (38%), Positives = 245/413 (59%), Gaps = 8/413 (1%)
Query: 1 MQLFLLLCLVLLSPQGASLHRHHPREMKKRVEDLHVGATVAPSS--RRDFTFDLYRALAS 58
M FL L L++L A++H P AT+ S DF F+LYR
Sbjct: 1 MSPFLYLVLLVLGLH-ATIHCASPEGKVTACHSSQPNATLYKMSSINADFAFNLYRRFTV 59
Query: 59 AAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQEL 118
P ++IFFSPVSIS +L MLS GA ST+ +I+E LG NL + E+ GFQ L+ L
Sbjct: 60 ETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSL 119
Query: 119 NQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAK 178
N P+ +L +GNALF + F++ +KTLY + F T+F + + A ++IN +V
Sbjct: 120 NFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEM 179
Query: 179 QTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQE-QDFYVTSETVVRVPMMS 237
QTKGK+V L+++L N ++++VNYI FKA+W F+ T++ F + T V+VPMM
Sbjct: 180 QTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMH 239
Query: 238 REDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKR 297
+ +QY++L+D L+C V+ + Y NA ALF+LP EG+M+ VE +S KTL+KW ++ +K
Sbjct: 240 QMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKG 299
Query: 298 QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDE 357
++L++PKFSI +Y L L +GI + ++ +AD SG++ + +++S HKAV+ + E
Sbjct: 300 WVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGE 359
Query: 358 SGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNRP 406
GT AAA + + ++ +R F++ I++ +ILFLGKV P
Sbjct: 360 KGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 278 bits (711), Expect = 6e-75
Identities = 151/405 (37%), Positives = 237/405 (58%), Gaps = 14/405 (3%)
Query: 10 VLLSPQGASLHRHHPREMKKRVE----DLHVGATVAPSSRRDFTFDLYRALASAAPSQSI 65
VLL+ +G PR K E + A D F L + LA P ++I
Sbjct: 13 VLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNI 72
Query: 66 FFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGF 125
F SP+SIS + +ML LGA ST +I +G N +K EK+LH GF ++ EL Q
Sbjct: 73 FLSPLSISTAFSMLCLGAQDSTLDEIKQGF--NFRKMPEKDLHEGFHYIIHELTQKTQDL 130
Query: 126 QLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIV 185
+LS+GN LF D + Q F+ K Y A+T TNF++ A KQIND+++++T GKI
Sbjct: 131 KLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKIN 190
Query: 186 DLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYL 245
+L++N+D V+++ NYIFF+A+W+ F+ T+E+DF++ + V+VPMM R Y
Sbjct: 191 NLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVG 250
Query: 246 LDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPK 305
D LSC ++ +PYQ N TA+FILP EGK++ +E GL T +W + +R +++ +P+
Sbjct: 251 YDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPR 310
Query: 306 FSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAA 365
+ G++ L+K L +G+S +F H DL+ I+ H +++V E VHKA +++DE GT AA
Sbjct: 311 LHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAG 370
Query: 366 TGTIFTFRSARLNSQRLV-FNRPFLMFIVDN---NILFLGKVNRP 406
TG ++ + + +V ++P+L+ I ++LFLGK+ P
Sbjct: 371 TGA----QTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 220 bits (560), Expect = 2e-57
Identities = 114/241 (47%), Positives = 164/241 (68%), Gaps = 5/241 (2%)
Query: 171 QINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQ-DFYVTSET 229
+IN +V K+T+GK+VD+++ LD +++VN+IFFKAKWE F+ + T++ F V +
Sbjct: 92 RINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQV 151
Query: 230 VVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRK 289
V VPMM +++Q+ + +D L+C V+ + Y+G+A A F+LPS+GKM+Q+E LS +TLRK
Sbjct: 152 TVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRK 211
Query: 290 WLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVH 349
W +KR +E+++P+FSI SY LE +LP +GI NVF +AD SGI+ ++QVS+ H
Sbjct: 212 WSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATH 271
Query: 350 KAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMFIVD---NNILFLGKVNR 405
KAV++V E GT A AAT T F RS S V FNR FLM I + + ILFLGKV
Sbjct: 272 KAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVEN 331
Query: 406 P 406
P
Sbjct: 332 P 332
Score = 37.4 bits (85), Expect = 0.025
Identities = 22/55 (40%), Positives = 29/55 (52%), Gaps = 4/55 (7%)
Query: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGL 97
S DF F LYR L PSQ+IFFSP I+ + + G + I++GL L
Sbjct: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQG----KVVDIIQGLDL 114
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 202 bits (515), Expect = 3e-52
Identities = 121/381 (31%), Positives = 213/381 (55%), Gaps = 23/381 (6%)
Query: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLN--LQKSSEK 105
F FDL++ + + +IF+SP+SI+ +L M+ LGA +T QI + L + + ++EK
Sbjct: 11 FMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEK 69
Query: 106 ----------ELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLA 155
+H FQ+LL E N+ D ++L + N LF + ++ A+K Y
Sbjct: 70 AATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQT 129
Query: 156 DTFPTNFRDSAG-AMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETS 212
T+F ++ + K+IN +V QT KI +L + + ++ +++VN I+FK +WE
Sbjct: 130 SVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENK 189
Query: 213 FNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFIL-PS 271
F + T+E+ F+ T V MM + + +++ L ++ +V+ +PY+G ++ +L P+
Sbjct: 190 FKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPN 249
Query: 272 E-GKMQQVENGLSEKTLRKWLKMFKKRQ--LELYLPKFSIEGSYQLEKVLPSLGISNVFT 328
E +Q++E L+ + L +W + R+ ++L+LP+F +E SY L+ L ++G+ N+F
Sbjct: 250 EIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFN 309
Query: 329 SHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPF 388
ADLSG++ + VS+++HKA VEV E G AAAAT + S+ ++ N PF
Sbjct: 310 GDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPF 369
Query: 389 LMFI---VDNNILFLGKVNRP 406
L FI N+ILF G+ + P
Sbjct: 370 LFFIRQNKTNSILFYGRFSSP 390
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 199 bits (507), Expect = 3e-51
Identities = 119/381 (31%), Positives = 206/381 (54%), Gaps = 23/381 (6%)
Query: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILE------------GL 95
F FDL++ + + +IF+SP+SI+ +L M+ LGA +T QI + G
Sbjct: 11 FMFDLFQQFRKSKEN-NIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGK 69
Query: 96 GLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLA 155
+H FQ+LL E N+ D ++L + N LF + ++ A+K Y
Sbjct: 70 AATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQT 129
Query: 156 DTFPTNFRDSAG-AMKQINDYVAKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETS 212
+F ++ + K+IN +V QT KI +L+ N+ SN +++VN I+FK +WE
Sbjct: 130 SVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKK 189
Query: 213 FNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFIL-PS 271
FN + T+E+ F+ T + MM + +H+ ++ +V+ +PY+G ++ +L P+
Sbjct: 190 FNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPN 249
Query: 272 E-GKMQQVENGLSEKTLRKW--LKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT 328
E +Q++E L+ + L +W L+ ++ +++L+LP+F +E SY L+ L ++G+ ++F
Sbjct: 250 EIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFN 309
Query: 329 SHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPF 388
ADLSG++ + +S ++HKA VEV E G AAAAT + S ++ N PF
Sbjct: 310 GDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPF 369
Query: 389 LMFI---VDNNILFLGKVNRP 406
L FI N+ILF G+ + P
Sbjct: 370 LFFIRQNKTNSILFYGRFSSP 390
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 194 bits (492), Expect = 2e-49
Identities = 127/370 (34%), Positives = 197/370 (53%), Gaps = 15/370 (4%)
Query: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL 107
F L + L PS ++F SPVSIS +LAM+ LGA +T Q+ + L LN +E+++
Sbjct: 11 FAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN----TEEDI 66
Query: 108 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF-RDSA 166
HR FQ LL E+N+ + L N LF + TF + Y A+ +F R +
Sbjct: 67 HRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAE 126
Query: 167 GAMKQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224
+ K IN +V+K+T+GKI +LL ++D+ +++VN I+FK KW F+ T+E F
Sbjct: 127 ESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFK 186
Query: 225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFIL-PSEG-KMQQVENGL 282
+ E V MM +E + + +++ +PY +L +L P +G ++ VE L
Sbjct: 187 INQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELSTVEKSL 246
Query: 283 SEKTLRKWLK--MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTS-HADLSGISNH 339
+ + L W K K ++E+ LPKF ++ Y +E VL LGI + F ADLS +S
Sbjct: 247 TFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAE 306
Query: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVD---NN 396
++ +S+ VHK+ VEV+E GT AAAA+ + R + PFL FI N+
Sbjct: 307 RDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANS 366
Query: 397 ILFLGKVNRP 406
ILF G+ + P
Sbjct: 367 ILFCGRFSSP 376
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 192 bits (487), Expect = 6e-49
Identities = 129/393 (32%), Positives = 209/393 (53%), Gaps = 30/393 (7%)
Query: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQK- 101
+S F +L + LA +A ++IFFS SIS SL ++ LGA +T Q+ + L N +
Sbjct: 6 TSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRDQG 65
Query: 102 -----------------SSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDT 144
S+ +E+H FQ L+ E+ +P D + L NA++ + +
Sbjct: 66 VKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFHNK 125
Query: 145 FVSAMKTLYLADTFPTNFRDSAGAM-KQINDYVAKQTKGKIVDLL--KNLDSNAVVIMVN 201
++ MKT + A+ P NF +++ + K IN +V +QT+GKI +LL ++DS +I+VN
Sbjct: 126 YLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMILVN 185
Query: 202 YIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQG 261
++FK WE F + T E+ F + T V MM + + H + + Y+
Sbjct: 186 ALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYYKS 245
Query: 262 NATALFILPSE--GKMQQVENGLSEKTLRKWLK--MFKKRQLELYLPKFSIEGSYQLEKV 317
+L IL E ++Q+E ++ + L +W M + +++L+LPKF +E SY L+
Sbjct: 246 RDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLKST 305
Query: 318 LPSLGISNVFT-SHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSAR 376
L S+G+S+ F+ S AD SG+S+ N+ +S + HKA VE++E GT AAA +G+ R R
Sbjct: 306 LSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIR-IR 364
Query: 377 LNSQRLVFNRPFLMFI---VDNNILFLGKVNRP 406
+ S N PFL FI N ILF G++ P
Sbjct: 365 VPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 190 bits (483), Expect = 2e-48
Identities = 118/365 (32%), Positives = 195/365 (53%), Gaps = 9/365 (2%)
Query: 47 DFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 106
+F F L R + S ++ FSP +S+++ L LGA T+ QI GL L K ++
Sbjct: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139
Query: 107 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 166
L + L+E L+ G+ F D+++TF + K + + P NFR+++
Sbjct: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199
Query: 167 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 226
A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++
Sbjct: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259
Query: 227 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 285
++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+
Sbjct: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319
Query: 286 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 344
+ WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV
Sbjct: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379
Query: 345 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG 401
S ++ + V+EVDE GT A A I + +A + +RPF I + +LFLG
Sbjct: 380 SRVLQRTVIEVDERGTEAVAG---ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 436
Query: 402 KVNRP 406
+V P
Sbjct: 437 RVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 190 bits (483), Expect = 2e-48
Identities = 118/365 (32%), Positives = 195/365 (53%), Gaps = 9/365 (2%)
Query: 47 DFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 106
+F F L R + S ++ FSP +S+++ L LGA T+ QI GL L K ++
Sbjct: 81 NFGFSLLRKI-SMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPG 139
Query: 107 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 166
L + L+E L+ G+ F D+++TF + K + + P NFR+++
Sbjct: 140 LLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNAS 199
Query: 167 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 226
A + +N Y+ K+T+GKI L ++ +I+V+YI FK KW T F+ T+ F++
Sbjct: 200 QAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLD 259
Query: 227 SETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFILPSE-GKMQQVENGLSEK 285
++VPMM ++ D+N C V+ +PYQGNAT L +L + G +E+ L+
Sbjct: 260 KYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTD 319
Query: 286 TLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGIS-NHSNIQV 344
+ WL+ K R +E++ PKF ++ Y++ ++L +GI +F+ ADLS +S N+QV
Sbjct: 320 LVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQV 379
Query: 345 SEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDNN---ILFLG 401
S ++ + V+EVDE GT A A I + +A + +RPF I + +LFLG
Sbjct: 380 SRVLQRTVIEVDERGTEAVAG---ILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLG 436
Query: 402 KVNRP 406
+V P
Sbjct: 437 RVVNP 441
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 189 bits (481), Expect = 3e-48
Identities = 128/379 (33%), Positives = 205/379 (54%), Gaps = 20/379 (5%)
Query: 43 SSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKS 102
S+ F DL+ AL+ P+ +IF SP SIS ++AM+ LG +T Q+ + N
Sbjct: 6 SANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN---- 61
Query: 103 SEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF 162
+ +E+H FQ L ++N+ + L L N L+ + + F+ + + Y AD +F
Sbjct: 62 TVEEVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASVDF 121
Query: 163 RD-SAGAMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSFNHKGTQ 219
+ S A K IN +V QT+GKI +LL + +D+ +++VN I+FK W+ F + T
Sbjct: 122 QHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEATT 181
Query: 220 EQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFIL------PSEG 273
F + + V MM ++ ++ Y +L CRV+ +PYQG ++ IL
Sbjct: 182 NAPFRLNKKDRKTVKMMYQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIEDEST 241
Query: 274 KMQQVENGLSEKTLRKWLKMFKKRQLE--LYLPKFSIEGSYQLEKVLPSLGISNVF-TSH 330
++++E L+ + L +W K +E + LP+F +E SY L L LG+ ++F +S
Sbjct: 242 GLKKIEEQLTLEKLHEWTKPENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQDLFNSSK 301
Query: 331 ADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLM 390
ADLSG+S +I +S++VHK+ VEV+E GT AAAAT I TF + + + PFL
Sbjct: 302 ADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATF-CMLMPEENFTADHPFLF 360
Query: 391 FIVDN---NILFLGKVNRP 406
FI N +ILFLG+ + P
Sbjct: 361 FIRHNSSGSILFLGRFSSP 379
>gi|8393956 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 13 [Homo sapiens]
Length = 391
Score = 187 bits (475), Expect = 1e-47
Identities = 117/381 (30%), Positives = 211/381 (55%), Gaps = 26/381 (6%)
Query: 50 FDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQ------KSS 103
FDL++ L +IFFSPV I ++ M+ LG +T Q+ E + K+
Sbjct: 13 FDLFKELKKTNDG-NIFFSPVGILTAIGMVLLGTRGATASQLEEVFHSEKETKSSRIKAE 71
Query: 104 EKEL-------HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLAD 156
EKE+ H+ FQ+ L E+++ + ++L++ N LF + ++ ++ Y A
Sbjct: 72 EKEVIENTEAVHQQFQKFLTEISKLTNDYELNITNRLFGEKTYLFLQKYLDYVEKYYHAS 131
Query: 157 TFPTNFRDSAG-AMKQINDYVAKQTKGKIVDLLKN--LDSNAVVIMVNYIFFKAKWETSF 213
P +F ++A + K+IN +V +T KI DL + + S+ +++VN ++FK +W+ F
Sbjct: 132 LEPVDFVNAADESRKKINSWVESKTNEKIKDLFPDGSISSSTKLVLVNMVYFKGQWDREF 191
Query: 214 NHKGTQEQDFYVTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPYQGNATALFI-LPSE 272
+ T+E+ F++ T V MM++ + + +L +++G+PY+ N ++F+ LP++
Sbjct: 192 KKENTKEEKFWMNKSTSKSVQMMTQSHSFSFTFLEDLQAKILGIPYKNNDLSMFVLLPND 251
Query: 273 -GKMQQVENGLSEKTLRKWLK--MFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTS 329
++++ + +S + L +W ++R++ L+LP+F +E Y LE VL ++G+ + F+
Sbjct: 252 IDGLEKIIDKISPEKLVEWTSPGHMEERKVNLHLPRFEVEDGYDLEAVLAAMGMGDAFSE 311
Query: 330 H-ADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPF 388
H AD SG+S+ S + + +H + V V E GT AAAATG FT SA + + N PF
Sbjct: 312 HKADYSGMSSGSGLYAQKFLHSSFVAVTEEGTEAAAATGIGFTVTSAP-GHENVHCNHPF 370
Query: 389 LMFI---VDNNILFLGKVNRP 406
L FI N+ILF G+ + P
Sbjct: 371 LFFIRHNESNSILFFGRFSSP 391
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 186 bits (473), Expect = 3e-47
Identities = 124/370 (33%), Positives = 199/370 (53%), Gaps = 17/370 (4%)
Query: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL 107
F L++ L S+++FFSP+SIS +LAM+ +GA ST Q+ + L L + ++
Sbjct: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY----KDGDI 66
Query: 108 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF-RDSA 166
HRGFQ LL E+N+ + L N LF + D F + Y A+ +F D+
Sbjct: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
Query: 167 GAMKQINDYVAKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224
K IND+VA++T+GKI ++L +D +++VN I+FK KW F+ K T+ +
Sbjct: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM-LF 185
Query: 225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPY-QGNATALFILPSEGK-MQQVENGL 282
T+E V MM +E ++ + +V+ +PY + + + +LP + + VE L
Sbjct: 186 KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
Query: 283 SEKTLRKWLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNH 339
+ + + W K K +++++LP+ +E SY LE L LG+ + F + AD SG+S
Sbjct: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
Query: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNN 396
N+ +S++ HK VEV+E GT AAAAT + R +R+ R + PFL FI N
Sbjct: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFLFFIRHHKTNC 364
Query: 397 ILFLGKVNRP 406
ILF G+ + P
Sbjct: 365 ILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 186 bits (473), Expect = 3e-47
Identities = 124/370 (33%), Positives = 199/370 (53%), Gaps = 17/370 (4%)
Query: 48 FTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKEL 107
F L++ L S+++FFSP+SIS +LAM+ +GA ST Q+ + L L + ++
Sbjct: 11 FAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLY----KDGDI 66
Query: 108 HRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNF-RDSA 166
HRGFQ LL E+N+ + L N LF + D F + Y A+ +F D+
Sbjct: 67 HRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTE 126
Query: 167 GAMKQINDYVAKQTKGKIVDLLK--NLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFY 224
K IND+VA++T+GKI ++L +D +++VN I+FK KW F+ K T+ +
Sbjct: 127 ECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGM-LF 185
Query: 225 VTSETVVRVPMMSREDQYHYLLDRNLSCRVVGVPY-QGNATALFILPSEGK-MQQVENGL 282
T+E V MM +E ++ + +V+ +PY + + + +LP + + VE L
Sbjct: 186 KTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLAVVEKAL 245
Query: 283 SEKTLRKWLKMFK--KRQLELYLPKFSIEGSYQLEKVLPSLGISNVFT-SHADLSGISNH 339
+ + + W K K +++++LP+ +E SY LE L LG+ + F + AD SG+S
Sbjct: 246 TYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADFSGMSTE 305
Query: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFI---VDNN 396
N+ +S++ HK VEV+E GT AAAAT + R +R+ R + PFL FI N
Sbjct: 306 KNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRM-EPRFCADHPFLFFIRHHKTNC 364
Query: 397 ILFLGKVNRP 406
ILF G+ + P
Sbjct: 365 ILFCGRFSSP 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,345,516
Number of Sequences: 37866
Number of extensions: 542879
Number of successful extensions: 1620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1415
Number of HSP's gapped (non-prelim): 69
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.