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Search of human proteins with 19072794
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a
[Homo sapiens]
(191 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a [Ho... 383 e-107
gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 383 e-107
gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 383 e-107
gi|9966809 kappa B-ras 1 [Homo sapiens] 277 3e-75
gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b [Ho... 236 9e-63
gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c [Ho... 115 3e-26
gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo sapi... 73 1e-13
gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens] 73 2e-13
gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo ... 72 2e-13
gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens] 72 3e-13
gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Hom... 72 4e-13
gi|33946329 ras related v-ral simian leukemia viral oncogene hom... 70 8e-13
gi|7661922 RAB21, member RAS oncogene family [Homo sapiens] 70 8e-13
gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog ... 69 2e-12
gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog is... 69 2e-12
gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform... 69 2e-12
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 68 5e-12
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 67 7e-12
gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens] 66 2e-11
gi|192807327 Ras-related associated with diabetes [Homo sapiens] 66 2e-11
gi|4759054 Ras-related associated with diabetes [Homo sapiens] 66 2e-11
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 65 3e-11
gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens] 65 4e-11
gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens] 65 4e-11
gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens] 64 8e-11
gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens] 64 8e-11
gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog i... 64 1e-10
gi|22027486 RASD family, member 2 [Homo sapiens] 63 1e-10
gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens] 63 2e-10
gi|34485714 Ras-related protein Rab-23 [Homo sapiens] 62 2e-10
>gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 383 bits (984), Expect = e-107
Identities = 191/191 (100%), Positives = 191/191 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
Query: 181 RKNKGSGSLDG 191
RKNKGSGSLDG
Sbjct: 181 RKNKGSGSLDG 191
>gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 383 bits (984), Expect = e-107
Identities = 191/191 (100%), Positives = 191/191 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
Query: 181 RKNKGSGSLDG 191
RKNKGSGSLDG
Sbjct: 181 RKNKGSGSLDG 191
>gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 383 bits (984), Expect = e-107
Identities = 191/191 (100%), Positives = 191/191 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
Query: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN
Sbjct: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
Query: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
Sbjct: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
Query: 181 RKNKGSGSLDG 191
RKNKGSGSLDG
Sbjct: 181 RKNKGSGSLDG 191
>gi|9966809 kappa B-ras 1 [Homo sapiens]
Length = 192
Score = 277 bits (709), Expect = 3e-75
Identities = 135/189 (71%), Positives = 160/189 (84%), Gaps = 1/189 (0%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+ Y
Sbjct: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQLHLY 60
Query: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
DTRGL++G ELP+H FS DG+VLVYS ++ ESFQRVELLKKEIDK KDKKEV IVVLGN
Sbjct: 61 DTRGLQEGVELPKHYFSFADGFVLVYSVNNLESFQRVELLKKEIDKFKDKKEVAIVVLGN 120
Query: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPL- 179
K DL EQR+VD +VAQ WAKSEKV+LWEV+V DR++L+EPF LASK++QPQSKS+FPL
Sbjct: 121 KIDLSEQRQVDAEVAQQWAKSEKVRLWEVTVTDRKTLIEPFTLLASKLSQPQSKSSFPLP 180
Query: 180 SRKNKGSGS 188
RKNKG+ +
Sbjct: 181 GRKNKGNSN 189
>gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b [Homo
sapiens]
Length = 135
Score = 236 bits (602), Expect = 9e-63
Identities = 132/191 (69%), Positives = 135/191 (70%), Gaps = 56/191 (29%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFY 60
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD---------- 50
Query: 61 DTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGN 120
RG+R+ +VTIVVLGN
Sbjct: 51 --RGVRE--------------------------------------------QVTIVVLGN 64
Query: 121 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 180
KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS
Sbjct: 65 KCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLS 124
Query: 181 RKNKGSGSLDG 191
RKNKGSGSLDG
Sbjct: 125 RKNKGSGSLDG 135
>gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c
[Homo sapiens]
Length = 97
Score = 115 bits (287), Expect = 3e-26
Identities = 56/57 (98%), Positives = 57/57 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV 57
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
>gi|5454028 related RAS viral (r-ras) oncogene homolog [Homo
sapiens]
Length = 218
Score = 73.2 bits (178), Expect = 1e-13
Identities = 53/185 (28%), Positives = 89/185 (48%), Gaps = 6/185 (3%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ Q + V S+ T ED Y D G+ ++ DT G
Sbjct: 31 KLVVVGGGGVGKSALTIQFIQSYFV--SDYDPTIEDSYTKICSVD-GIPARLDILDTAGQ 87
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + G++LV++ + R+SF V L +I + KD+ + +V++GNK DL+
Sbjct: 88 EEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLE 147
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKS---AFPLSRK 182
QR+V A + S V +E S R ++ E F L + + Q + + P + +
Sbjct: 148 SQRQVPRSEASAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPR 207
Query: 183 NKGSG 187
KG G
Sbjct: 208 KKGGG 212
>gi|15718761 c-K-ras2 protein isoform b precursor [Homo sapiens]
Length = 188
Score = 72.8 bits (177), Expect = 2e-13
Identities = 53/181 (29%), Positives = 93/181 (51%), Gaps = 4/181 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF+ + +++I + KD ++V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNKG 185
R VD AQ A+S + E S R+ + + F L ++ + + K + +K K
Sbjct: 121 PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK 180
Query: 186 S 186
S
Sbjct: 181 S 181
>gi|4506405 v-ral simian leukemia viral oncogene homolog B [Homo
sapiens]
Length = 206
Score = 72.4 bits (176), Expect = 2e-13
Identities = 56/187 (29%), Positives = 96/187 (51%), Gaps = 10/187 (5%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KV++ G VGK+++ Q +Y V E T+ D Y + D G Q+ DT G
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYE--PTKADSYRKKVVLD-GEEVQIDILDTAGQ 72
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSK-DKKEVTIVVLGNKCDL 124
D A + + F +G++LV+S ESF +++I + K ++ ++ ++V+GNK DL
Sbjct: 73 EDYAAIRDNYFRSGEGFLLVFSITEHESFTATAEFREQILRVKAEEDKIPLLVVGNKSDL 132
Query: 125 QEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYL-----ASKMTQPQSKSAFPL 179
+E+R+V + A+ A+ V+ E S R ++ + F L KM++ + K+
Sbjct: 133 EERRQVPVEEARSKAEEWGVQYVETSAKTRANVDKVFFDLMREIRTKKMSENKDKNG-KK 191
Query: 180 SRKNKGS 186
S KNK S
Sbjct: 192 SSKNKKS 198
>gi|15718763 c-K-ras2 protein isoform a precursor [Homo sapiens]
Length = 189
Score = 72.0 bits (175), Expect = 3e-13
Identities = 54/182 (29%), Positives = 94/182 (51%), Gaps = 7/182 (3%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF+ + +++I + KD ++V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNKG 185
R VD AQ A+S + E S R+ + + F L ++ Q + K +S++ K
Sbjct: 121 PSRTVDTKQAQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKK---ISKEEKT 177
Query: 186 SG 187
G
Sbjct: 178 PG 179
>gi|4505451 neuroblastoma RAS viral (v-ras) oncogene homolog [Homo
sapiens]
Length = 189
Score = 71.6 bits (174), Expect = 4e-13
Identities = 52/169 (30%), Positives = 86/169 (50%), Gaps = 4/169 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF + L +++I + KD +V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSK 174
R VD A AKS + E S R+ + + F L ++ Q + K
Sbjct: 121 PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMK 169
>gi|33946329 ras related v-ral simian leukemia viral oncogene
homolog A [Homo sapiens]
Length = 206
Score = 70.5 bits (171), Expect = 8e-13
Identities = 50/175 (28%), Positives = 87/175 (49%), Gaps = 8/175 (4%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KV++ G VGK+++ Q +Y V E T+ D Y + D G Q+ DT G
Sbjct: 16 KVIMVGSGGVGKSALTLQFMYDEFVEDYE--PTKADSYRKKVVLD-GEEVQIDILDTAGQ 72
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
D A + + F +G++ V+S ESF +++I + K+ + V +++GNK DL+
Sbjct: 73 EDYAAIRDNYFRSGEGFLCVFSITEMESFAATADFREQILRVKEDENVPFLLVGNKSDLE 132
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYL-----ASKMTQPQSKS 175
++R+V + A++ A+ V E S R ++ + F L A KM + K+
Sbjct: 133 DKRQVSVEEAKNRAEQWNVNYVETSAKTRANVDKVFFDLMREIRARKMEDSKEKN 187
>gi|7661922 RAB21, member RAS oncogene family [Homo sapiens]
Length = 225
Score = 70.5 bits (171), Expect = 8e-13
Identities = 52/185 (28%), Positives = 90/185 (48%), Gaps = 8/185 (4%)
Query: 4 SCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTR 63
S KVV+ G+ VGKTS++ L Y + + I T + ++ G R + +DT
Sbjct: 19 SFKVVLLGEGCVGKTSLV--LRYCENKFNDKHITTLQASFLTKKLNIGGKRVNLAIWDTA 76
Query: 64 GLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCD 123
G L + ++G +LVY +SFQ+V+ KE+ K E+ + ++GNK D
Sbjct: 77 GQERFHALGPIYYRDSNGAILVYDITDEDSFQKVKNWVKELRKMLGN-EICLCIVGNKID 135
Query: 124 LQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKN 183
L+++R V A+ +A+S K + S + + E F+ L +M + + +
Sbjct: 136 LEKERHVSIQEAESYAESVGAKHYHTSAKQNKGIEELFLDLCKRMIETAQ-----VDERA 190
Query: 184 KGSGS 188
KG+GS
Sbjct: 191 KGNGS 195
>gi|194363762 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 69.3 bits (168), Expect = 2e-12
Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF+ + +++I + KD +V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNKG 185
R V+ AQ A+S + E S R+ + + F L ++ Q + + P G
Sbjct: 121 AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG 180
>gi|4885425 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 1 [Homo sapiens]
Length = 189
Score = 69.3 bits (168), Expect = 2e-12
Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 4/180 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF+ + +++I + KD +V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNKG 185
R V+ AQ A+S + E S R+ + + F L ++ Q + + P G
Sbjct: 121 AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG 180
>gi|21361416 related RAS viral (r-ras) oncogene homolog 2 isoform a
[Homo sapiens]
Length = 204
Score = 68.9 bits (167), Expect = 2e-12
Identities = 48/174 (27%), Positives = 83/174 (47%), Gaps = 5/174 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGS-IETDRGVREQVRFYDTRG 64
++VV G VGK+++ Q + V + T ED Y + DR R + DT G
Sbjct: 16 RLVVVGGGGVGKSALTIQFIQSYFVTDYD--PTIEDSYTKQCVIDDRAARLDI--LDTAG 71
Query: 65 LRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDL 124
+ + +G++LV+S R SF+ + +++I + KD+ E ++++GNK DL
Sbjct: 72 QEEFGAMREQYMRTGEGFLLVFSVTDRGSFEEIYKFQRQILRVKDRDEFPMILIGNKADL 131
Query: 125 QEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFP 178
QR+V + Q A+ KV E S R ++ + F L + + Q + P
Sbjct: 132 DHQRQVTQEEGQQLARQLKVTYMEASAKIRMNVDQAFHELVRVIRKFQEQECPP 185
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 67.8 bits (164), Expect = 5e-12
Identities = 46/163 (28%), Positives = 80/163 (49%), Gaps = 3/163 (1%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KVVV G VGK+++ Q + G+ + + T ED Y IE D + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGSFI--EKYDPTIEDFYRKEIEVDSSP-SVLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
A + G++LVYS +++SFQ ++ ++ +I + K + V ++++GNK DL+
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYERVPMILVGNKVDLE 121
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKM 168
+R V + A+ E S ++ S+ E F + +M
Sbjct: 122 GEREVSYGEGKALAEEWSCPFMETSAKNKASVDELFAEIVRQM 164
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 67.4 bits (163), Expect = 7e-12
Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KVVV G VGK+++ Q + G + + T ED Y IE D + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFI--EKYDPTIEDFYRKEIEVDSSP-SVLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
A + G++LVYS +++SFQ ++ ++ +I + K ++V ++++GNK DL+
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEKVPVILVGNKVDLE 121
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKM 168
+R V + A+ E S + + E F + +M
Sbjct: 122 SEREVSSSEGRALAEEWGCPFMETSAKSKTMVDELFAEIVRQM 164
>gi|21389385 Ras homolog enriched in brain like 1 [Homo sapiens]
Length = 183
Score = 66.2 bits (160), Expect = 2e-11
Identities = 49/150 (32%), Positives = 70/150 (46%), Gaps = 3/150 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KVV+ G VGKTS+ Q + G G + T E+ Y I T + DT G
Sbjct: 8 KVVILGYRCVGKTSLAHQFVEGEFSEGYD--PTVENTY-SKIVTLGKDEFHLHLVDTAGQ 64
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + LP GYVLVYS S SFQ +E L +++ + K V +V++GNK DL
Sbjct: 65 DEYSILPYSFIIGVHGYVLVYSVTSLHSFQVIESLYQKLHEGHGKTRVPVVLVGNKADLS 124
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRR 155
+R V + A+S E S + +
Sbjct: 125 PEREVQAVEGKKLAESWGATFMESSARENQ 154
>gi|192807327 Ras-related associated with diabetes [Homo sapiens]
Length = 308
Score = 66.2 bits (160), Expect = 2e-11
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KV++ G VGK+++ ++G G E E Y SI D G + YD
Sbjct: 93 KVLLLGAPGVGKSALAR--IFGGVEDGPEA-EAAGHTYDRSIVVD-GEEASLMVYDIWEQ 148
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
G LP HC + D YV+VYS + SF++ L+ ++ +++ +V I+++GNK DL
Sbjct: 149 DGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLV 208
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVA 152
R V D + A K E S A
Sbjct: 209 RSREVSVDEGRACAVVFDCKFIETSAA 235
>gi|4759054 Ras-related associated with diabetes [Homo sapiens]
Length = 308
Score = 66.2 bits (160), Expect = 2e-11
Identities = 46/147 (31%), Positives = 70/147 (47%), Gaps = 4/147 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KV++ G VGK+++ ++G G E E Y SI D G + YD
Sbjct: 93 KVLLLGAPGVGKSALAR--IFGGVEDGPEA-EAAGHTYDRSIVVD-GEEASLMVYDIWEQ 148
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
G LP HC + D YV+VYS + SF++ L+ ++ +++ +V I+++GNK DL
Sbjct: 149 DGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRARQTDDVPIILVGNKSDLV 208
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVA 152
R V D + A K E S A
Sbjct: 209 RSREVSVDEGRACAVVFDCKFIETSAA 235
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 65.5 bits (158), Expect = 3e-11
Identities = 45/163 (27%), Positives = 78/163 (47%), Gaps = 3/163 (1%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
KVVV G VGK+++ Q + G + + T ED Y IE D + DT G
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFI--EKYDPTIEDFYRKEIEVDSSP-SVLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
A + G++LVYS +++SFQ ++ ++ +I + K ++V ++++GNK DL+
Sbjct: 62 EQFASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEKVPLILVGNKVDLE 121
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKM 168
+R V + A+ E S + + E F + +M
Sbjct: 122 PEREVMSSEGRALAQEWGCPFMETSAKSKSMVDELFAEIVRQM 164
>gi|58219792 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 65.1 bits (157), Expect = 4e-11
Identities = 50/185 (27%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ Q + G V + T ED Y +E D + + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFV--EKYDPTIEDSYRKQVEVD-AQQCMLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ G+ LVYS ++ +F ++ L+++I + KD +V ++++GNKCDL+
Sbjct: 62 EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
Query: 126 EQRRVDPDVAQHWAKS-EKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNK 184
++R V + Q+ A+ E S + ++ E F L ++ + K+ P + K
Sbjct: 122 DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR---KTPVPGKARKK 178
Query: 185 GSGSL 189
S L
Sbjct: 179 SSCQL 183
>gi|7661678 RAP1B, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 65.1 bits (157), Expect = 4e-11
Identities = 50/185 (27%), Positives = 89/185 (48%), Gaps = 7/185 (3%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ Q + G V + T ED Y +E D + + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFV--EKYDPTIEDSYRKQVEVD-AQQCMLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ G+ LVYS ++ +F ++ L+++I + KD +V ++++GNKCDL+
Sbjct: 62 EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLE 121
Query: 126 EQRRVDPDVAQHWAKS-EKVKLWEVSVADRRSLLEPFVYLASKMTQPQSKSAFPLSRKNK 184
++R V + Q+ A+ E S + ++ E F L ++ + K+ P + K
Sbjct: 122 DERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINR---KTPVPGKARKK 178
Query: 185 GSGSL 189
S L
Sbjct: 179 SSCQL 183
>gi|58331202 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 63.9 bits (154), Expect = 8e-11
Identities = 40/135 (29%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ Q + G V + T ED Y +E D + + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFV--EKYDPTIEDSYRKQVEVDCQ-QCMLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ G+ LVYS ++ +F ++ L+++I + KD ++V ++++GNKCDL+
Sbjct: 62 EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
Query: 126 EQRRVDPDVAQHWAK 140
++R V + Q+ A+
Sbjct: 122 DERVVGKEQGQNLAR 136
>gi|4506413 RAP1A, member of RAS oncogene family [Homo sapiens]
Length = 184
Score = 63.9 bits (154), Expect = 8e-11
Identities = 40/135 (29%), Positives = 72/135 (53%), Gaps = 3/135 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ Q + G V + T ED Y +E D + + DT G
Sbjct: 5 KLVVLGSGGVGKSALTVQFVQGIFV--EKYDPTIEDSYRKQVEVDCQ-QCMLEILDTAGT 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ G+ LVYS ++ +F ++ L+++I + KD ++V ++++GNKCDL+
Sbjct: 62 EQFTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTEDVPMILVGNKCDLE 121
Query: 126 EQRRVDPDVAQHWAK 140
++R V + Q+ A+
Sbjct: 122 DERVVGKEQGQNLAR 136
>gi|34222246 v-Ha-ras Harvey rat sarcoma viral oncogene homolog
isoform 2 [Homo sapiens]
Length = 170
Score = 63.5 bits (153), Expect = 1e-10
Identities = 46/150 (30%), Positives = 78/150 (52%), Gaps = 4/150 (2%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTRGL 65
K+VV G VGK+++ QL+ NH V E T ED Y + D G + DT G
Sbjct: 5 KLVVVGAGGVGKSALTIQLIQ-NHFV-DEYDPTIEDSYRKQVVID-GETCLLDILDTAGQ 61
Query: 66 RDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVTIVVLGNKCDLQ 125
+ + + +G++ V++ ++ +SF+ + +++I + KD +V +V++GNKCDL
Sbjct: 62 EEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL- 120
Query: 126 EQRRVDPDVAQHWAKSEKVKLWEVSVADRR 155
R V+ AQ A+S + E S R+
Sbjct: 121 AARTVESRQAQDLARSYGIPYIETSAKTRQ 150
>gi|22027486 RASD family, member 2 [Homo sapiens]
Length = 266
Score = 63.2 bits (152), Expect = 1e-10
Identities = 56/182 (30%), Positives = 83/182 (45%), Gaps = 13/182 (7%)
Query: 4 SCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQVRFYDTR 63
S ++VV G + VGK+SI+ + L G + T ED + + RG Q+ DT
Sbjct: 19 SYRMVVLGASRVGKSSIVSRFLNGRFE--DQYTPTIEDFH-RKVYNIRGDMYQLDILDTS 75
Query: 64 GLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEI--------DKSKDKKEVTI 115
G + R D ++LV+S D+RESF V+ L+K+I +K+K+ E+ +
Sbjct: 76 GNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPM 135
Query: 116 VVLGNKCDLQEQRRVDPDVAQHWAKS--EKVKLWEVSVADRRSLLEPFVYLASKMTQPQS 173
V+ GNK D E R P S E +EVS ++ E F L S P
Sbjct: 136 VICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHE 195
Query: 174 KS 175
S
Sbjct: 196 MS 197
>gi|7706359 RAS, dexamethasone-induced 1 [Homo sapiens]
Length = 281
Score = 62.8 bits (151), Expect = 2e-10
Identities = 53/191 (27%), Positives = 88/191 (46%), Gaps = 28/191 (14%)
Query: 3 KSC-KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIE-------TDRGVR 54
K+C ++V+ G + VGKT+I+ + L G ED Y +IE + RG
Sbjct: 22 KNCYRMVILGSSKVGKTAIVSRFLTGRF----------EDAYTPTIEDFHRKFYSIRGEV 71
Query: 55 EQVRFYDTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEI--------DK 106
Q+ DT G + R D ++LV+S D+R+SF+ V+ L+++I +K
Sbjct: 72 YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNK 131
Query: 107 SKDKKEVTIVVLGNKCDLQEQRRVDPDVAQHWA--KSEKVKLWEVSVADRRSLLEPFVYL 164
+K+ +V +V+ GNK D R VD + ++ +E+S SL + F L
Sbjct: 132 TKENVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRAL 191
Query: 165 ASKMTQPQSKS 175
+ P S
Sbjct: 192 FAMAKLPSEMS 202
>gi|34485714 Ras-related protein Rab-23 [Homo sapiens]
Length = 237
Score = 62.4 bits (150), Expect = 2e-10
Identities = 47/176 (26%), Positives = 86/176 (48%), Gaps = 16/176 (9%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYG------NHVVGSEMIETQEDIYVGSIETDRGVR 54
M + K+VV G +VGK+S++++ G +G + +E Q + D VR
Sbjct: 6 MEVAIKMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQV------NDEDVR 59
Query: 55 EQVRFYDTRGLRDGAELPRHCFSCTDGYVLVYSTDSRESFQRVELLKKEIDKSKDKKEVT 114
+ +DT G + + + + VLV+ST RESF+ V ++++ + ++
Sbjct: 60 --LMLWDTAGQEEFDAITKAYYRGAQACVLVFSTTDRESFEAVSSWREKV--VAEVGDIP 115
Query: 115 IVVLGNKCDLQEQRRVDPDVAQHWAKSEKVKLWEVSVADRRSLLEPFVYLASKMTQ 170
V++ NK DL + + + A+ AK K++ + SV + ++ E F YLA K Q
Sbjct: 116 TVLVQNKIDLLDDSCIKNEEAEALAKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQ 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,827,649
Number of Sequences: 37866
Number of extensions: 271663
Number of successful extensions: 1111
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 112
Number of HSP's successfully gapped in prelim test: 83
Number of HSP's that attempted gapping in prelim test: 909
Number of HSP's gapped (non-prelim): 199
length of query: 191
length of database: 18,247,518
effective HSP length: 96
effective length of query: 95
effective length of database: 14,612,382
effective search space: 1388176290
effective search space used: 1388176290
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.