Guide to the Human Genome
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Search of human proteins with 10801345

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10801345 eukaryotic translation initiation factor 3, subunit
12 [Homo sapiens]
         (218 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10801345 eukaryotic translation initiation factor 3, subunit ...   442   e-124
gi|169168320 PREDICTED: similar to hCG39609 [Homo sapiens]            268   3e-72
gi|239748615 PREDICTED: similar to hCG39609 [Homo sapiens]            268   3e-72
gi|239742640 PREDICTED: similar to hCG39609 [Homo sapiens]            268   3e-72
gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]                29   2.7  
gi|7019499 peroxisome proliferator-activated receptor gamma, coa...    29   3.5  
gi|46399200 testis-specific bromodomain protein [Homo sapiens]         29   3.5  
gi|46399198 testis-specific bromodomain protein [Homo sapiens]         29   3.5  
gi|71773415 annexin VI isoform 2 [Homo sapiens]                        28   4.6  
gi|71773329 annexin VI isoform 1 [Homo sapiens]                        28   4.6  
gi|151101151 coiled-coil domain containing 2 isoform b [Homo sap...    28   6.0  
gi|151101140 coiled-coil domain containing 2 isoform a [Homo sap...    28   6.0  
gi|151105223 coiled-coil domain containing 2 isoform a [Homo sap...    28   6.0  
gi|151105229 coiled-coil domain containing 2 isoform a [Homo sap...    28   6.0  
gi|239755109 PREDICTED: hypothetical protein XP_002346219 [Homo ...    28   7.9  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    28   7.9  

>gi|10801345 eukaryotic translation initiation factor 3, subunit 12
           [Homo sapiens]
          Length = 218

 Score =  442 bits (1137), Expect = e-124
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF 60
           MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF
Sbjct: 1   MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF 60

Query: 61  FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA 120
           FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA
Sbjct: 61  FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA 120

Query: 121 LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS 180
           LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS
Sbjct: 121 LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS 180

Query: 181 ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ 218
           ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ
Sbjct: 181 ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ 218


>gi|169168320 PREDICTED: similar to hCG39609 [Homo sapiens]
          Length = 183

 Score =  268 bits (685), Expect = 3e-72
 Identities = 148/218 (67%), Positives = 156/218 (71%), Gaps = 35/218 (16%)

Query: 1   MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF 60
           M +FEQMRANVG LL+GI+R NPE LATLE YVE QAK+ AYDLEAN  VLKLYQ NP F
Sbjct: 1   MVIFEQMRANVGMLLQGINRNNPEKLATLECYVEMQAKDTAYDLEANPVVLKLYQSNPVF 60

Query: 61  FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA 120
           FQTT TAQI LKALTNLPHT+FT                                    +
Sbjct: 61  FQTTDTAQIQLKALTNLPHTNFT-----------------------------------PS 85

Query: 121 LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS 180
           LDEN+DLLEGITGFEDSVR  IC VVGITYQHID WLLAEM G LSDSQLKVWM KY W 
Sbjct: 86  LDENVDLLEGITGFEDSVRMCICPVVGITYQHIDHWLLAEMPGYLSDSQLKVWMRKYTWR 145

Query: 181 ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ 218
           ADES QIFICSQEE+IKPKN VEKIDFDSVSSIMA  Q
Sbjct: 146 ADESQQIFICSQEENIKPKNPVEKIDFDSVSSIMAFFQ 183


>gi|239748615 PREDICTED: similar to hCG39609 [Homo sapiens]
          Length = 183

 Score =  268 bits (685), Expect = 3e-72
 Identities = 148/218 (67%), Positives = 156/218 (71%), Gaps = 35/218 (16%)

Query: 1   MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF 60
           M +FEQMRANVG LL+GI+R NPE LATLE YVE QAK+ AYDLEAN  VLKLYQ NP F
Sbjct: 1   MVIFEQMRANVGMLLQGINRNNPEKLATLECYVEMQAKDTAYDLEANPVVLKLYQSNPVF 60

Query: 61  FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA 120
           FQTT TAQI LKALTNLPHT+FT                                    +
Sbjct: 61  FQTTDTAQIQLKALTNLPHTNFT-----------------------------------PS 85

Query: 121 LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS 180
           LDEN+DLLEGITGFEDSVR  IC VVGITYQHID WLLAEM G LSDSQLKVWM KY W 
Sbjct: 86  LDENVDLLEGITGFEDSVRMCICPVVGITYQHIDHWLLAEMPGYLSDSQLKVWMRKYTWR 145

Query: 181 ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ 218
           ADES QIFICSQEE+IKPKN VEKIDFDSVSSIMA  Q
Sbjct: 146 ADESQQIFICSQEENIKPKNPVEKIDFDSVSSIMAFFQ 183


>gi|239742640 PREDICTED: similar to hCG39609 [Homo sapiens]
          Length = 183

 Score =  268 bits (685), Expect = 3e-72
 Identities = 148/218 (67%), Positives = 156/218 (71%), Gaps = 35/218 (16%)

Query: 1   MAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAF 60
           M +FEQMRANVG LL+GI+R NPE LATLE YVE QAK+ AYDLEAN  VLKLYQ NP F
Sbjct: 1   MVIFEQMRANVGMLLQGINRNNPEKLATLECYVEMQAKDTAYDLEANPVVLKLYQSNPVF 60

Query: 61  FQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWQA 120
           FQTT TAQI LKALTNLPHT+FT                                    +
Sbjct: 61  FQTTDTAQIQLKALTNLPHTNFT-----------------------------------PS 85

Query: 121 LDENMDLLEGITGFEDSVRKFICHVVGITYQHIDRWLLAEMLGDLSDSQLKVWMSKYGWS 180
           LDEN+DLLEGITGFEDSVR  IC VVGITYQHID WLLAEM G LSDSQLKVWM KY W 
Sbjct: 86  LDENVDLLEGITGFEDSVRMCICPVVGITYQHIDHWLLAEMPGYLSDSQLKVWMRKYTWR 145

Query: 181 ADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMASSQ 218
           ADES QIFICSQEE+IKPKN VEKIDFDSVSSIMA  Q
Sbjct: 146 ADESQQIFICSQEENIKPKNPVEKIDFDSVSSIMAFFQ 183


>gi|28875786 FCH and double SH3 domains 1 [Homo sapiens]
          Length = 690

 Score = 29.3 bits (64), Expect = 2.7
 Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%)

Query: 34  ETQAKENAY--DLEANLAVLKLYQFN--PAFFQTTVT--AQILLKALTNLPHTDFTLCKC 87
           + QA  N Y  +L A  A L  Y     PA  +  V+  ++ L   LT+L HT+    + 
Sbjct: 203 QLQAARNEYLLNLVATNAHLDHYYQEELPALLKALVSELSEHLRDPLTSLSHTELEAAEV 262

Query: 88  MIDQAHQEERPIRQILYLGDL 108
           +++ AH+ E+   Q+ +  DL
Sbjct: 263 ILEHAHRGEQTTSQVSWEQDL 283


>gi|7019499 peroxisome proliferator-activated receptor gamma,
           coactivator 1 alpha [Homo sapiens]
          Length = 798

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 15/52 (28%), Positives = 30/52 (57%), Gaps = 3/52 (5%)

Query: 164 DLSDSQLKVWMSKYGWSADESGQIFICSQEESIKPKNIVEKIDFDSVSSIMA 215
           D++D     ++    W +D+S    I S + + +P NI EKID ++ ++++A
Sbjct: 42  DVNDLDTDSFLGGLKWCSDQSE---IISNQYNNEPSNIFEKIDEENEANLLA 90


>gi|46399200 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 22  NPENLATLERYVETQAKENAYDLEAN--LAVLKLYQFNPAFFQTTVTAQIL 70
           NP +L T++  ++ Q  ++AY   A+  L  +  Y++NP   +    A++L
Sbjct: 315 NPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARML 365


>gi|46399198 testis-specific bromodomain protein [Homo sapiens]
          Length = 947

 Score = 28.9 bits (63), Expect = 3.5
 Identities = 14/51 (27%), Positives = 28/51 (54%), Gaps = 2/51 (3%)

Query: 22  NPENLATLERYVETQAKENAYDLEAN--LAVLKLYQFNPAFFQTTVTAQIL 70
           NP +L T++  ++ Q  ++AY   A+  L  +  Y++NP   +    A++L
Sbjct: 315 NPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARML 365


>gi|71773415 annexin VI isoform 2 [Homo sapiens]
          Length = 667

 Score = 28.5 bits (62), Expect = 4.6
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 48  LAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQI 102
           LAV+K  +  P +F     A+ L KA+  L   D TL + M+ ++  +   IR+I
Sbjct: 243 LAVVKCIRSTPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREI 292


>gi|71773329 annexin VI isoform 1 [Homo sapiens]
          Length = 673

 Score = 28.5 bits (62), Expect = 4.6
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 48  LAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQI 102
           LAV+K  +  P +F     A+ L KA+  L   D TL + M+ ++  +   IR+I
Sbjct: 243 LAVVKCIRSTPEYF-----AERLFKAMKGLGTRDNTLIRIMVSRSELDMLDIREI 292


>gi|151101151 coiled-coil domain containing 2 isoform b [Homo
           sapiens]
          Length = 372

 Score = 28.1 bits (61), Expect = 6.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 6   QMRANVGKLLKGIDRYNPENLATL--ERYVETQAKENAYDLEANLA 49
           ++   V KL KGI+ YN EN   L  E+  ET A E   +L+  LA
Sbjct: 107 ELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVE-IKELQGQLA 151


>gi|151101140 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 28.1 bits (61), Expect = 6.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 6   QMRANVGKLLKGIDRYNPENLATL--ERYVETQAKENAYDLEANLA 49
           ++   V KL KGI+ YN EN   L  E+  ET A E   +L+  LA
Sbjct: 107 ELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVE-IKELQGQLA 151


>gi|151105223 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 28.1 bits (61), Expect = 6.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 6   QMRANVGKLLKGIDRYNPENLATL--ERYVETQAKENAYDLEANLA 49
           ++   V KL KGI+ YN EN   L  E+  ET A E   +L+  LA
Sbjct: 107 ELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVE-IKELQGQLA 151


>gi|151105229 coiled-coil domain containing 2 isoform a [Homo
           sapiens]
          Length = 600

 Score = 28.1 bits (61), Expect = 6.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 3/46 (6%)

Query: 6   QMRANVGKLLKGIDRYNPENLATL--ERYVETQAKENAYDLEANLA 49
           ++   V KL KGI+ YN EN   L  E+  ET A E   +L+  LA
Sbjct: 107 ELTTEVNKLQKGIEMYNQENSVYLSYEKRAETLAVE-IKELQGQLA 151


>gi|239755109 PREDICTED: hypothetical protein XP_002346219 [Homo
           sapiens]
          Length = 115

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 18/55 (32%), Positives = 30/55 (54%), Gaps = 2/55 (3%)

Query: 70  LLKALTNLPHTDFTLCKC--MIDQAHQEERPIRQILYLGDLLETCHFQAFWQALD 122
           LLKA+ NLP +   +      I ++ QE++ +   + + DLL   HF  F +AL+
Sbjct: 19  LLKAVPNLPLSQSVVASGGGQIFESSQEDQELLLAMQILDLLLFAHFCLFSEALE 73


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 13/30 (43%), Positives = 17/30 (56%)

Query: 107  DLLETCHFQAFWQALDENMDLLEGITGFED 136
            DLLET   +   Q L  +  ++E I GFED
Sbjct: 3949 DLLETSSLETITQQLAHHKAMMEEIAGFED 3978


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,287,438
Number of Sequences: 37866
Number of extensions: 290799
Number of successful extensions: 708
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 697
Number of HSP's gapped (non-prelim): 22
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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