Search of human proteins with 18677731

Search of human proteins with 18677731

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18677731 MOB-LAK [Homo sapiens]
         (217 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18677731 MOB-LAK [Homo sapiens]                                    457   e-129
gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo ...   379   e-105
gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isofor...   354   3e-98
gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isofor...   354   3e-98
gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo ...   255   2e-68
gi|148747437 Mob4B protein [Homo sapiens]                             249   1e-66
gi|34594669 HCCA2 protein [Homo sapiens]                              130   7e-31
gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [H...    46   3e-05
gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Ho...    43   2e-04
gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Ho...    43   2e-04

>gi|18677731 MOB-LAK [Homo sapiens]
          Length = 217

 Score =  457 bits (1177), Expect = e-129
 Identities = 217/217 (100%), Positives = 217/217 (100%)

Query: 1   MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW 60
           MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
Sbjct: 1   MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW 60

Query: 61  VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD 120
           VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
Sbjct: 61  VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD 120

Query: 121 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE 180
           LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
Sbjct: 121 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE 180

Query: 181 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217
           AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
Sbjct: 181 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217


>gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo
           sapiens]
          Length = 216

 Score =  379 bits (972), Expect = e-105
 Identities = 174/212 (82%), Positives = 193/212 (91%)

Query: 6   LKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHV 65
           LKQVFNKDKTFRPKRKFEPGTQRFELHK+AQASLN+G+DL+ AVQLP GED NDWVAVHV
Sbjct: 5   LKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHV 64

Query: 66  VDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDW 125
           VDFFNR+NLIYGTI + CTE++CPVMSGGPKYEYRWQD+ K++KPTAL AP+YM+LLMDW
Sbjct: 65  VDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDW 124

Query: 126 IEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNT 185
           IE QINNE++FPT VG PFPKNFLQ  +KIL RLFRVFVHVYIHHFDR+  MG+EAHVNT
Sbjct: 125 IEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNT 184

Query: 186 CYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217
           CYKHFYYFV E  LID KELEPLKEMT+RMCH
Sbjct: 185 CYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216


>gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isoform 1
           [Homo sapiens]
          Length = 268

 Score =  354 bits (909), Expect = 3e-98
 Identities = 157/212 (74%), Positives = 188/212 (88%)

Query: 6   LKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHV 65
           LKQVF KDKTFRP+++FEPGTQRFEL+KKAQASL +GLDLR  V+LPPGE+++DW+AVHV
Sbjct: 57  LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHV 116

Query: 66  VDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDW 125
           VDFFNR+NLIYGT+++ C+E SCPVM+GGP+YEYRWQDE ++R+P  LSAPRYM LLMDW
Sbjct: 117 VDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDW 176

Query: 126 IEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNT 185
           IE  IN+E++FPT VG PFPKNF Q   KIL+RLFRVFVHVYIHHFD I  MG+EAHVNT
Sbjct: 177 IEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNT 236

Query: 186 CYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217
           CYKHFYYF++EF L+D +ELEPL+EMT R+CH
Sbjct: 237 CYKHFYYFIREFSLVDQRELEPLREMTERICH 268


>gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isoform 2
           [Homo sapiens]
          Length = 216

 Score =  354 bits (909), Expect = 3e-98
 Identities = 157/212 (74%), Positives = 188/212 (88%)

Query: 6   LKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHV 65
           LKQVF KDKTFRP+++FEPGTQRFEL+KKAQASL +GLDLR  V+LPPGE+++DW+AVHV
Sbjct: 5   LKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWIAVHV 64

Query: 66  VDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDW 125
           VDFFNR+NLIYGT+++ C+E SCPVM+GGP+YEYRWQDE ++R+P  LSAPRYM LLMDW
Sbjct: 65  VDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMALLMDW 124

Query: 126 IEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNT 185
           IE  IN+E++FPT VG PFPKNF Q   KIL+RLFRVFVHVYIHHFD I  MG+EAHVNT
Sbjct: 125 IEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEAHVNT 184

Query: 186 CYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217
           CYKHFYYF++EF L+D +ELEPL+EMT R+CH
Sbjct: 185 CYKHFYYFIREFSLVDQRELEPLREMTERICH 216


>gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo
           sapiens]
          Length = 216

 Score =  255 bits (651), Expect = 2e-68
 Identities = 111/202 (54%), Positives = 154/202 (76%), Gaps = 1/202 (0%)

Query: 14  KTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVN 73
           KTF+PK+    G+ ++EL K A+A+L +G +LR+AV LP GEDLN+WVAV+ VDFFN++N
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQIN 69

Query: 74  LIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNE 133
           ++YGTI+D CTE+SCPVMS GPKYEY W D    +KP   SAP+Y+D LM W++ Q+++E
Sbjct: 70  MLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 134 DLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYF 193
            LFP+ +G PFPKNF+   + IL RLFRV+ H+Y  HFD + Q+  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFF 189

Query: 194 VKEFGLIDTKELEPLKEMTARM 215
           V+EF LID +EL PL+E+  ++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|148747437 Mob4B protein [Homo sapiens]
          Length = 216

 Score =  249 bits (637), Expect = 1e-66
 Identities = 108/202 (53%), Positives = 152/202 (75%), Gaps = 1/202 (0%)

Query: 14  KTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVN 73
           KTF+PK+    G+ ++EL K A+A+L +G +LR AV LP GEDLN+W+AV+ VDFFN++N
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQIN 69

Query: 74  LIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNE 133
           ++YGTI++ CTE SCPVMS GP+YEY W D    +KP   SAP+Y+D LM W++ Q+++E
Sbjct: 70  MLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 134 DLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYF 193
            LFP+ +G PFPKNF+   + IL RLFRV+ H+Y  HFD + Q+  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFF 189

Query: 194 VKEFGLIDTKELEPLKEMTARM 215
           V+EF LID +EL PL+E+  ++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|34594669 HCCA2 protein [Homo sapiens]
          Length = 237

 Score =  130 bits (328), Expect = 7e-31
 Identities = 65/168 (38%), Positives = 94/168 (55%), Gaps = 3/168 (1%)

Query: 49  VQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFR 108
           V LP   DLN+W+A +   FF+ +NL Y TIS+ CT ++C  M+     +Y W DE    
Sbjct: 44  VVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVC-NTQYYWYDERG-- 100

Query: 109 KPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYI 168
           K    +AP+Y+D +M  ++  + +ED+FPT  G  FP +F   VRKI   LF V  H+Y 
Sbjct: 101 KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAHIYW 160

Query: 169 HHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMC 216
            HF     +    H+NT Y HF  F +EF L+D KE   + ++T  +C
Sbjct: 161 AHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLC 208


>gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [Homo
           sapiens]
          Length = 204

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 39/186 (20%), Positives = 79/186 (42%), Gaps = 11/186 (5%)

Query: 20  RKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTI 79
           R+  PGT+   + +  +A  +   ++   ++ P G+D   W   H+  F   +N +   +
Sbjct: 11  RRNRPGTKAQYIQQNIRADCS---NIDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKL 67

Query: 80  SDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTN 139
              C   +C  M+   ++ +     HK   P    A  Y    +D     +N+   FP+ 
Sbjct: 68  QSECHPDTCTQMTATEQWIFLCA-AHK--TPKECPAIDYTRHTLDGAACLLNSNKYFPSR 124

Query: 140 VGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGL 199
           V     ++ +  +  +  R++R+F H Y HH     +  +E  +  C++ F  FV ++ L
Sbjct: 125 VS--IKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFL--CHR-FTKFVMKYNL 179

Query: 200 IDTKEL 205
           +    L
Sbjct: 180 MSKDNL 185


>gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Homo
           sapiens]
          Length = 225

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 38/189 (20%), Positives = 77/189 (40%), Gaps = 9/189 (4%)

Query: 18  PKRKFEPGTQRFELHKKAQASLNAGL-DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIY 76
           P   F+       + +  Q ++ A   ++   ++ P G+D   W   H+  F   +N + 
Sbjct: 26  PDESFDEMDSTLAVQQYIQQNIRADCSNIDKILEPPEGQDEGVWKYEHLRQFCLELNGLA 85

Query: 77  GTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDWIEAQINNEDLF 136
             +   C   +C  M+   ++ +     HK   P    A  Y    +D     +N+   F
Sbjct: 86  VKLQSECHPDTCTQMTATEQWIFLCA-AHK--TPKECPAIDYTRHTLDGAACLLNSNKYF 142

Query: 137 PTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKE 196
           P+ V     ++ +  +  +  R++R+F H Y HH     +  +E  +  C++ F  FV +
Sbjct: 143 PSRVS--IKESSVAKLGSVCRRIYRIFSHAYFHHRQIFDEYENETFL--CHR-FTKFVMK 197

Query: 197 FGLIDTKEL 205
           + L+    L
Sbjct: 198 YNLMSKDNL 206


>gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Homo
           sapiens]
          Length = 193

 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 34/154 (22%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 52  PPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPT 111
           P G+D   W   H+  F   +N +   +   C   +C  M+   ++ +     HK   P 
Sbjct: 29  PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA-AHK--TPK 85

Query: 112 ALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHF 171
              A  Y    +D     +N+   FP+ V     ++ +  +  +  R++R+F H Y HH 
Sbjct: 86  ECPAIDYTRHTLDGAACLLNSNKYFPSRVS--IKESSVAKLGSVCRRIYRIFSHAYFHHR 143

Query: 172 DRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKEL 205
               +  +E  +  C++ F  FV ++ L+    L
Sbjct: 144 QIFDEYENETFL--CHR-FTKFVMKYNLMSKDNL 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.139    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,724,676
Number of Sequences: 37866
Number of extensions: 377467
Number of successful extensions: 821
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 811
Number of HSP's gapped (non-prelim): 10
length of query: 217
length of database: 18,247,518
effective HSP length: 98
effective length of query: 119
effective length of database: 14,536,650
effective search space: 1729861350
effective search space used: 1729861350
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.