Guide to the Human Genome
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Search of human proteins with 16950633

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|16950633 argininosuccinate synthetase 1 [Homo sapiens]
         (412 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|16950633 argininosuccinate synthetase 1 [Homo sapiens]             833   0.0  
gi|53759107 argininosuccinate synthetase 1 [Homo sapiens]             833   0.0  
gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapi...    33   0.36 
gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapi...    33   0.36 
gi|74229025 membralin isoform 1 [Homo sapiens]                         30   3.1  
gi|15529970 membralin isoform 2 [Homo sapiens]                         30   3.1  
gi|22748791 hypothetical protein LOC126868 [Homo sapiens]              29   6.8  

>gi|16950633 argininosuccinate synthetase 1 [Homo sapiens]
          Length = 412

 Score =  833 bits (2153), Expect = 0.0
 Identities = 412/412 (100%), Positives = 412/412 (100%)

Query: 1   MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 60
           MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF
Sbjct: 1   MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 60

Query: 61  IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 120
           IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG
Sbjct: 61  IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 120

Query: 121 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 180
           KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS
Sbjct: 121 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 180

Query: 181 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 240
           MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD
Sbjct: 181 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 240

Query: 241 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 300
           GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF
Sbjct: 241 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 300

Query: 301 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 360
           TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI
Sbjct: 301 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 360

Query: 361 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 412
           LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK
Sbjct: 361 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 412


>gi|53759107 argininosuccinate synthetase 1 [Homo sapiens]
          Length = 412

 Score =  833 bits (2153), Expect = 0.0
 Identities = 412/412 (100%), Positives = 412/412 (100%)

Query: 1   MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 60
           MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF
Sbjct: 1   MSSKGSVVLAYSGGLDTSCILVWLKEQGYDVIAYLANIGQKEDFEEARKKALKLGAKKVF 60

Query: 61  IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 120
           IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG
Sbjct: 61  IEDVSREFVEEFIWPAIQSSALYEDRYLLGTSLARPCIARKQVEIAQREGAKYVSHGATG 120

Query: 121 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 180
           KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS
Sbjct: 121 KGNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWS 180

Query: 181 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 240
           MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD
Sbjct: 181 MDENLMHISYEAGILENPKNQAPPGLYTKTQDPAKAPNTPDILEIEFKKGVPVKVTNVKD 240

Query: 241 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 300
           GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF
Sbjct: 241 GTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFIGMKSRGIYETPAGTILYHAHLDIEAF 300

Query: 301 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 360
           TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI
Sbjct: 301 TMDREVRKIKQGLGLKFAELVYTGFWHSPECEFVRHCIAKSQERVEGKVQVSVLKGQVYI 360

Query: 361 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 412
           LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK
Sbjct: 361 LGRESPLSLYNEELVSMNVQGDYEPTDATGFININSLRLKEYHRLQSKVTAK 412


>gi|71834863 Rho GTPase activating protein 5 isoform a [Homo sapiens]
          Length = 1502

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 20/164 (12%)

Query: 162  EYAKQHGIPIPVTPK------NPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAK 215
            ++ + H +P P+ PK      N   +D NL+  + EAGI +NP+ Q         +D   
Sbjct: 1029 DHERNHKVPPPIKPKPVVPKTNVKKLDPNLLK-TIEAGIGKNPRKQTSRVPLAHPEDMDP 1087

Query: 216  APNTPDILEIEFK-KGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFI 274
            + N  + ++  FK KG   ++  V D + ++  +    ++N   G    G  D   ++  
Sbjct: 1088 SDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIR-NSFVNNTQGDEENGFSDRT-SKSH 1145

Query: 275  GMKSRGIYETPAGTILYHAH----------LDIEAFTMDREVRK 308
            G +    Y+  + T+   A            D EAFT  +  RK
Sbjct: 1146 GERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRK 1189


>gi|71834861 Rho GTPase activating protein 5 isoform b [Homo sapiens]
          Length = 1501

 Score = 33.5 bits (75), Expect = 0.36
 Identities = 39/164 (23%), Positives = 69/164 (42%), Gaps = 20/164 (12%)

Query: 162  EYAKQHGIPIPVTPK------NPWSMDENLMHISYEAGILENPKNQAPPGLYTKTQDPAK 215
            ++ + H +P P+ PK      N   +D NL+  + EAGI +NP+ Q         +D   
Sbjct: 1029 DHERNHKVPPPIKPKPVVPKTNVKKLDPNLLK-TIEAGIGKNPRKQTSRVPLAHPEDMDP 1087

Query: 216  APNTPDILEIEFK-KGVPVKVTNVKDGTTHQTSLELFMYLNEVAGKHGVGRIDIVENRFI 274
            + N  + ++  FK KG   ++  V D + ++  +    ++N   G    G  D   ++  
Sbjct: 1088 SDNYAEPIDTIFKQKGYSDEIYVVPDDSQNRIKIR-NSFVNNTQGDEENGFSDRT-SKSH 1145

Query: 275  GMKSRGIYETPAGTILYHAH----------LDIEAFTMDREVRK 308
            G +    Y+  + T+   A            D EAFT  +  RK
Sbjct: 1146 GERRPSKYKYKSKTLFSKAKSYYRRTHSDASDDEAFTTSKTKRK 1189


>gi|74229025 membralin isoform 1 [Homo sapiens]
          Length = 620

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 17/74 (22%)

Query: 122 GNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSM 181
           GN  ++FEL       + KV  P    E        ND  E+      P P TP   W  
Sbjct: 164 GNSSIKFELDI-----EPKVFKPPSSTE------ALNDSQEF------PFPETPTKVWPQ 206

Query: 182 DENLMHISYEAGIL 195
           DE ++  S E G L
Sbjct: 207 DEYIVEYSLEYGFL 220


>gi|15529970 membralin isoform 2 [Homo sapiens]
          Length = 408

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 23/74 (31%), Positives = 29/74 (39%), Gaps = 17/74 (22%)

Query: 122 GNDQVRFELSCYSLAPQIKVIAPWRMPEFYNRFKGRNDLMEYAKQHGIPIPVTPKNPWSM 181
           GN  ++FEL       + KV  P    E        ND  E+      P P TP   W  
Sbjct: 164 GNSSIKFELDI-----EPKVFKPPSSTE------ALNDSQEF------PFPETPTKVWPQ 206

Query: 182 DENLMHISYEAGIL 195
           DE ++  S E G L
Sbjct: 207 DEYIVEYSLEYGFL 220


>gi|22748791 hypothetical protein LOC126868 [Homo sapiens]
          Length = 362

 Score = 29.3 bits (64), Expect = 6.8
 Identities = 18/49 (36%), Positives = 24/49 (48%), Gaps = 2/49 (4%)

Query: 98  IARKQVEIAQREGAKYVSHGATGKGNDQVRFELSCYS--LAPQIKVIAP 144
           + R+Q+  A  E  K V H  T   N  +RF+   YS      IKV+AP
Sbjct: 19  LRRQQISQAVEEVQKVVHHLTTNISNQDIRFQAVPYSDTYNENIKVLAP 67


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,373,506
Number of Sequences: 37866
Number of extensions: 695948
Number of successful extensions: 1540
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1538
Number of HSP's gapped (non-prelim): 7
length of query: 412
length of database: 18,247,518
effective HSP length: 105
effective length of query: 307
effective length of database: 14,271,588
effective search space: 4381377516
effective search space used: 4381377516
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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