Search of human proteins with 157168360

Search of human proteins with 157168360

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|157168360 acetylserotonin O-methyltransferase [Homo sapiens]
         (373 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|157168360 acetylserotonin O-methyltransferase [Homo sapiens]       753   0.0  
gi|117553627 acetylserotonin O-methyltransferase-like [Homo sapi...   236   2e-62
gi|239754279 PREDICTED: hypothetical protein XP_002345940 [Homo ...    56   5e-08
gi|239748812 PREDICTED: hypothetical protein XP_002346807 [Homo ...    56   5e-08
gi|239740912 PREDICTED: hypothetical protein XP_002344084 [Homo ...    56   5e-08
gi|239740849 PREDICTED: hypothetical protein XP_002344051 [Homo ...    56   5e-08
gi|10863935 reticulon 1 isoform A [Homo sapiens]                       29   6.0  

>gi|157168360 acetylserotonin O-methyltransferase [Homo sapiens]
          Length = 373

 Score =  753 bits (1945), Expect = 0.0
 Identities = 373/373 (100%), Positives = 373/373 (100%)

Query: 1   MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60
           MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
Sbjct: 1   MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT 60

Query: 61  ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120
           ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
Sbjct: 61  ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL 120

Query: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180
           ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
Sbjct: 121 ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF 180

Query: 181 PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP 240
           PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
Sbjct: 181 PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP 240

Query: 241 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT 300
           EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
Sbjct: 241 EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT 300

Query: 301 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK 360
           CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
Sbjct: 301 CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK 360

Query: 361 KTGAIYDAILARK 373
           KTGAIYDAILARK
Sbjct: 361 KTGAIYDAILARK 373


>gi|117553627 acetylserotonin O-methyltransferase-like [Homo
           sapiens]
          Length = 621

 Score =  236 bits (603), Expect = 2e-62
 Identities = 146/365 (40%), Positives = 201/365 (55%), Gaps = 37/365 (10%)

Query: 12  LNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGTELLLDICVSLK 71
           L +   GFM+S+ L  AC+L VFDLL +   P   A +A+ V ASA G E LLDIC ++ 
Sbjct: 288 LLELIEGFMLSKGLLTACKLKVFDLLKDE-APQKAADIASKVDASACGMERLLDICAAMG 346

Query: 72  LLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHLADAVREGRNQY 131
           LL+   +G    Y NTE ++ YL +    S    + +    ++  + +L  A+REG NQ+
Sbjct: 347 LLEKTEQG----YSNTETANVYLASDGEYSLHGFIMHNNDLTWNLFTYLEFAIREGTNQH 402

Query: 132 LETFGVPAEELFT-AIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVFPLMCDLGGTW 190
               G  AE+LF  A Y+S   RL+FM+A+  +  +    V TAF+LS F   CD+GG  
Sbjct: 403 HRALGKKAEDLFQDAYYQSPETRLRFMRAMHGMTKLTACQVATAFNLSRFSSACDVGGC- 461

Query: 191 IKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIPEVVWTAKQHF 250
                                       GALA+E    YP  ++TVFD+P+++  A  HF
Sbjct: 462 ---------------------------TGALARELAREYPRMQVTVFDLPDIIELAA-HF 493

Query: 251 S--FQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHTCKPGGGIL 308
                +  QI F  GDFF+DPLP A+LY+L R+LHDW D K   LL R+  +CKPG G+L
Sbjct: 494 QPPGPQAVQIHFAAGDFFRDPLPSAELYVLCRILHDWPDDKVHKLLSRVAESCKPGAGLL 553

Query: 309 VIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFKKTGAIYDA 368
           ++E+LLDE++R      + SLNMLVQTEG+ER+   Y  LL   GF   Q    G + DA
Sbjct: 554 LVETLLDEEKRVAQRALMQSLNMLVQTEGKERSLGEYQCLLELHGFHQVQVVHLGGVLDA 613

Query: 369 ILARK 373
           ILA K
Sbjct: 614 ILATK 618


>gi|239754279 PREDICTED: hypothetical protein XP_002345940 [Homo
           sapiens]
          Length = 240

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 26/30 (86%), Positives = 28/30 (93%)

Query: 188 GTWIKLETIILSKLSQGQKTKHRVFSLIGG 217
           GTW+KLETIILSKLSQGQKTKH +FSLI G
Sbjct: 210 GTWMKLETIILSKLSQGQKTKHHMFSLIDG 239


>gi|239748812 PREDICTED: hypothetical protein XP_002346807 [Homo
           sapiens]
          Length = 240

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 26/30 (86%), Positives = 28/30 (93%)

Query: 188 GTWIKLETIILSKLSQGQKTKHRVFSLIGG 217
           GTW+KLETIILSKLSQGQKTKH +FSLI G
Sbjct: 210 GTWMKLETIILSKLSQGQKTKHHMFSLIDG 239


>gi|239740912 PREDICTED: hypothetical protein XP_002344084 [Homo
           sapiens]
          Length = 240

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 26/30 (86%), Positives = 28/30 (93%)

Query: 188 GTWIKLETIILSKLSQGQKTKHRVFSLIGG 217
           GTW+KLETIILSKLSQGQKTKH +FSLI G
Sbjct: 210 GTWMKLETIILSKLSQGQKTKHHMFSLIDG 239


>gi|239740849 PREDICTED: hypothetical protein XP_002344051 [Homo
           sapiens]
          Length = 240

 Score = 56.2 bits (134), Expect = 5e-08
 Identities = 26/30 (86%), Positives = 28/30 (93%)

Query: 188 GTWIKLETIILSKLSQGQKTKHRVFSLIGG 217
           GTW+KLETIILSKLSQGQKTKH +FSLI G
Sbjct: 210 GTWMKLETIILSKLSQGQKTKHHMFSLIDG 239


>gi|10863935 reticulon 1 isoform A [Homo sapiens]
          Length = 776

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 32/114 (28%), Positives = 47/114 (41%), Gaps = 25/114 (21%)

Query: 240 PEVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEA------DLYILARVLHDWADGKCSHL 293
           PE V   +QH    E++ +DF+  D      PE          +  +++ D       HL
Sbjct: 202 PEEVKHQEQHHPELEDKDLDFKNKDTDISIKPEGVREPDKPAPVEGKIIKD-------HL 254

Query: 294 LERIYHTCKPGGGILVIESLLDEDRRGPLLT-----QLYSLNMLVQTEGQERTP 342
           LE    T  P      I+ L +E RR P +T      L  +   V+T  QE+TP
Sbjct: 255 LEE--STFAP-----YIDDLSEEQRRAPQITTPVKITLTEIEPSVETTTQEKTP 301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,172,603
Number of Sequences: 37866
Number of extensions: 607216
Number of successful extensions: 1191
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1180
Number of HSP's gapped (non-prelim): 7
length of query: 373
length of database: 18,247,518
effective HSP length: 104
effective length of query: 269
effective length of database: 14,309,454
effective search space: 3849243126
effective search space used: 3849243126
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.