Guide to the Human Genome
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Search of human proteins with 110431368

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
isoform 1 [Homo sapiens]
         (495 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is...  1007   0.0  
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is...   908   0.0  
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso...   416   e-116
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is...   394   e-109
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso...   394   e-109
gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof...   382   e-106
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H...   369   e-102
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is...   137   3e-32
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof...   131   2e-30
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom...   124   2e-28
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom...   122   7e-28
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is...    92   8e-19
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is...    92   8e-19
gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens]     30   5.0  
gi|22748751 solute carrier family 43, member 2 [Homo sapiens]          30   6.6  
gi|196123591 cytochrome b [Homo sapiens neanderthalensis]              29   8.6  
gi|61743914 cholinergic receptor, nicotinic, gamma polypeptide p...    29   8.6  
gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]        29   8.6  

>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
           isoform 1 [Homo sapiens]
          Length = 495

 Score = 1007 bits (2603), Expect = 0.0
 Identities = 495/495 (100%), Positives = 495/495 (100%)

Query: 1   MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 60
           MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ
Sbjct: 1   MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 60

Query: 61  WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 120
           WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT
Sbjct: 61  WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 120

Query: 121 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 180
           FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL
Sbjct: 121 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 180

Query: 181 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 240
           GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY
Sbjct: 181 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 240

Query: 241 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 300
           THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS
Sbjct: 241 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 300

Query: 301 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH 360
           LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH
Sbjct: 301 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH 360

Query: 361 FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS 420
           FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS
Sbjct: 361 FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS 420

Query: 421 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV 480
           EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV
Sbjct: 421 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV 480

Query: 481 AVVGAALVQLFWLQD 495
           AVVGAALVQLFWLQD
Sbjct: 481 AVVGAALVQLFWLQD 495


>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
           isoform 2 [Homo sapiens]
          Length = 458

 Score =  908 bits (2346), Expect = 0.0
 Identities = 458/495 (92%), Positives = 458/495 (92%), Gaps = 37/495 (7%)

Query: 1   MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 60
           MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ
Sbjct: 1   MGLSRKEQVFLALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQ 60

Query: 61  WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 120
           WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT
Sbjct: 61  WLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPT 120

Query: 121 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 180
           FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL
Sbjct: 121 FLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGL 180

Query: 181 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 240
           GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY
Sbjct: 181 GTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVY 240

Query: 241 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 300
           THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS
Sbjct: 241 THSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLS 300

Query: 301 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFH 360
           LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFY          
Sbjct: 301 LPQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFY---------- 350

Query: 361 FLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFS 420
                                      VEASYPGQDRWLRDYCASGLYILTLLHEGYGFS
Sbjct: 351 ---------------------------VEASYPGQDRWLRDYCASGLYILTLLHEGYGFS 383

Query: 421 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV 480
           EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV
Sbjct: 384 EETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALV 443

Query: 481 AVVGAALVQLFWLQD 495
           AVVGAALVQLFWLQD
Sbjct: 444 AVVGAALVQLFWLQD 458


>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
           isoform 1 [Homo sapiens]
          Length = 495

 Score =  416 bits (1068), Expect = e-116
 Identities = 213/483 (44%), Positives = 296/483 (61%), Gaps = 14/483 (2%)

Query: 13  LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72
           LL A+G++GL   +LL V    V  P  +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13  LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69

Query: 73  SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132
            Q  +C V G GISSY  N + A +SL GCLE+AL  +P+ +H  TP +LGATAGMRLL+
Sbjct: 70  GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129

Query: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192
             N   +  +  AVT  L + P DF GA +L+GQ EG FGW+T NY L   +KY + G W
Sbjct: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189

Query: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252
            +P +  L GA+D+GGASTQITF    P  D++++    LYG  Y VYTHS+LC+GRDQ+
Sbjct: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248

Query: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310
           L RLL   +Q+       HPC+  G+ T + LG +Y+SPC  A  P +   +  +++ G+
Sbjct: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304

Query: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPL 370
            +P  C   +  LF+FSSC     C+F+GV+QPP+ G F AFS F+YT  FL  +   P+
Sbjct: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363

Query: 371 ST---VNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL 427
           +T   + A     C + W  ++A  PGQ   L DYCA  +++  LL  GYGF E  +  +
Sbjct: 364 ATLQQLEAAAVNVCNQTWAQLQARVPGQRARLADYCAGAMFVQQLLSRGYGFDERAFGGV 423

Query: 428 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL 487
            F+K+A    +GW LGYMLNLT +IPAD P   +   +  WV  ++    AL+A +   L
Sbjct: 424 IFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLL 483

Query: 488 VQL 490
            Q+
Sbjct: 484 RQV 486


>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
           isoform 2 [Homo sapiens]
          Length = 517

 Score =  394 bits (1011), Expect = e-109
 Identities = 217/495 (43%), Positives = 304/495 (61%), Gaps = 19/495 (3%)

Query: 11  LALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTG 70
           LA+LG S +  + AL+ + +     L P ++K+GIV DAGSSHTSL++Y+W A KEN TG
Sbjct: 25  LAILGFSSIIAVIALLAVGLTQNKAL-PENVKYGIVLDAGSSHTSLYIYKWPAEKENDTG 83

Query: 71  VVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRL 130
           VV Q   C+V+GPGIS +     + G  L  C+E A  +IP +QH++TP +LGATAGMRL
Sbjct: 84  VVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRL 143

Query: 131 LSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTG 190
           L  ++   A  +   V + L   P DF GA ++ GQ EGA+GWIT+NY LG   K+S   
Sbjct: 144 LRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQKT 200

Query: 191 EW--IQPPE---EMLVGALDMGGASTQITFVPGGPILDKSTQA-DFRLYGSDYSVYTHSY 244
            W  I P E   +   GALD+GGASTQ+TFVP    ++    A  FRLYG DY+VYTHS+
Sbjct: 201 RWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSF 260

Query: 245 LCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLP-Q 303
           LC+G+DQ L + L   +Q     +LR PC+  GY+  + +  LY++PC      ++LP Q
Sbjct: 261 LCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRF-EMTLPFQ 319

Query: 304 NLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLN 363
              ++G GN   C  +I ELFN S C     CAF+G++ PPL+G F AFS FY+   FLN
Sbjct: 320 QFEIQGIGNYQQCHQSILELFNTSYCP-YSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLN 378

Query: 364 LTSRQ-PLSTVNATIWEFCQRPWKLVEASYPG-QDRWLRDYCASGLYILTLLHEGYGFSE 421
           LTS +     V   + +FC +PW+ ++ SY G ++++L +YC SG YIL+LL +GY F+ 
Sbjct: 379 LTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTA 438

Query: 422 ETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQW-RAESYGVWVAKVVFMVLALV 480
           ++W  + F  +  G D GWTLGYMLNLT MIPA+ P     + S  V++  +  +VL  V
Sbjct: 439 DSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTV 498

Query: 481 AVVGAALV---QLFW 492
           A++G  +      FW
Sbjct: 499 AIIGLLIFHKPSYFW 513


>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
           isoform 1 [Homo sapiens]
          Length = 510

 Score =  394 bits (1011), Expect = e-109
 Identities = 217/495 (43%), Positives = 304/495 (61%), Gaps = 19/495 (3%)

Query: 11  LALLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTG 70
           LA+LG S +  + AL+ + +     L P ++K+GIV DAGSSHTSL++Y+W A KEN TG
Sbjct: 18  LAILGFSSIIAVIALLAVGLTQNKAL-PENVKYGIVLDAGSSHTSLYIYKWPAEKENDTG 76

Query: 71  VVSQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRL 130
           VV Q   C+V+GPGIS +     + G  L  C+E A  +IP +QH++TP +LGATAGMRL
Sbjct: 77  VVHQVEECRVKGPGISKFVQKVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRL 136

Query: 131 LSRKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTG 190
           L  ++   A  +   V + L   P DF GA ++ GQ EGA+GWIT+NY LG   K+S   
Sbjct: 137 LRMESEELADRVLDVVERSLSNYPFDFQGARIITGQEEGAYGWITINYLLG---KFSQKT 193

Query: 191 EW--IQPPE---EMLVGALDMGGASTQITFVPGGPILDKSTQA-DFRLYGSDYSVYTHSY 244
            W  I P E   +   GALD+GGASTQ+TFVP    ++    A  FRLYG DY+VYTHS+
Sbjct: 194 RWFSIVPYETNNQETFGALDLGGASTQVTFVPQNQTIESPDNALQFRLYGKDYNVYTHSF 253

Query: 245 LCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLP-Q 303
           LC+G+DQ L + L   +Q     +LR PC+  GY+  + +  LY++PC      ++LP Q
Sbjct: 254 LCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTKRF-EMTLPFQ 312

Query: 304 NLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLN 363
              ++G GN   C  +I ELFN S C     CAF+G++ PPL+G F AFS FY+   FLN
Sbjct: 313 QFEIQGIGNYQQCHQSILELFNTSYCP-YSQCAFNGIFLPPLQGDFGAFSAFYFVMKFLN 371

Query: 364 LTSRQ-PLSTVNATIWEFCQRPWKLVEASYPG-QDRWLRDYCASGLYILTLLHEGYGFSE 421
           LTS +     V   + +FC +PW+ ++ SY G ++++L +YC SG YIL+LL +GY F+ 
Sbjct: 372 LTSEKVSQEKVTEMMKKFCAQPWEEIKTSYAGVKEKYLSEYCFSGTYILSLLLQGYHFTA 431

Query: 422 ETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQW-RAESYGVWVAKVVFMVLALV 480
           ++W  + F  +  G D GWTLGYMLNLT MIPA+ P     + S  V++  +  +VL  V
Sbjct: 432 DSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAEQPLSTPLSHSTYVFLMVLFSLVLFTV 491

Query: 481 AVVGAALV---QLFW 492
           A++G  +      FW
Sbjct: 492 AIIGLLIFHKPSYFW 506


>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
           2 [Homo sapiens]
          Length = 472

 Score =  382 bits (982), Expect = e-106
 Identities = 204/483 (42%), Positives = 282/483 (58%), Gaps = 37/483 (7%)

Query: 13  LLGASGVSGLTALILLLVEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV 72
           LL A+G++GL   +LL V    V  P  +K+GIV DAGSSHTS+F+Y+W A+KEN TG+V
Sbjct: 13  LLAAAGLAGL---LLLCVPTRDVREPPALKYGIVLDAGSSHTSMFIYKWPADKENDTGIV 69

Query: 73  SQALACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLS 132
            Q  +C V G GISSY  N + A +SL GCLE+AL  +P+ +H  TP +LGATAGMRLL+
Sbjct: 70  GQHSSCDVPGGGISSYADNPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLN 129

Query: 133 RKNSSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEW 192
             N   +  +  AVT  L + P DF GA +L+GQ EG FGW+T NY L   +KY + G W
Sbjct: 130 LTNPEASTSVLMAVTHTLTQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKYGWVGRW 189

Query: 193 IQPPEEMLVGALDMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQM 252
            +P +  L GA+D+GGASTQITF    P  D++++    LYG  Y VYTHS+LC+GRDQ+
Sbjct: 190 FRPRKGTL-GAMDLGGASTQITFETTSPAEDRASEVQLHLYGQHYRVYTHSFLCYGRDQV 248

Query: 253 LSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGT 310
           L RLL   +Q+       HPC+  G+ T + LG +Y+SPC  A  P +   +  +++ G+
Sbjct: 249 LQRLLASALQTHGF----HPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNSSARVSLSGS 304

Query: 311 GNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPL 370
            +P  C   +  LF+FSSC     C+F+GV+QPP+ G F AFS F+YT  FL  +   P+
Sbjct: 305 SDPHLCRDLVSGLFSFSSCPFSR-CSFNGVFQPPVAGNFVAFSAFFYTVDFLRTSMGLPV 363

Query: 371 ST---VNATIWEFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSL 427
           +T   + A     C + W                          LL  GYGF E  +  +
Sbjct: 364 ATLQQLEAAAVNVCNQTW-----------------------AQQLLSRGYGFDERAFGGV 400

Query: 428 EFRKQAGGVDIGWTLGYMLNLTGMIPADAPAQWRAESYGVWVAKVVFMVLALVAVVGAAL 487
            F+K+A    +GW LGYMLNLT +IPAD P   +   +  WV  ++    AL+A +   L
Sbjct: 401 IFQKKAADTAVGWALGYMLNLTNLIPADPPGLRKGTDFSSWVVLLLLFASALLAALVLLL 460

Query: 488 VQL 490
            Q+
Sbjct: 461 RQV 463


>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
           sapiens]
          Length = 529

 Score =  369 bits (948), Expect = e-102
 Identities = 187/447 (41%), Positives = 263/447 (58%), Gaps = 11/447 (2%)

Query: 22  LTALILLLVEATSV------LLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQA 75
           L   I++LV  T +      +LP  +K+GIV DAGSS T++++YQW A KEN TGVVSQ 
Sbjct: 30  LLVSIVVLVSITVIQIHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVSQT 89

Query: 76  LACQVEGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKN 135
             C V+G GISSY +N      + + C+++    +P   H  TP  LGATAGMRLL  +N
Sbjct: 90  FKCSVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLLRLQN 149

Query: 136 SSQARDIFAAVTQVLGRSPVDFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQP 195
            + A ++  ++       P DF GA++++GQ EG +GWIT NY +G  ++ +    W+ P
Sbjct: 150 ETAANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNFLEKNLWHMWVHP 209

Query: 196 PEEMLVGALDMGGASTQITFVPGGPI-LDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLS 254
                 GALD+GGASTQI+FV G  + L+ S      LYG  Y++YTHS+ C+GR++   
Sbjct: 210 HGVETTGALDLGGASTQISFVAGEKMDLNTSDIMQVSLYGYVYTLYTHSFQCYGRNEAEK 269

Query: 255 RLLVGLVQSRPAA-LLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQN--LTVEGTG 311
           + L  L+Q+ P    L +PCY   Y  +  +G +++S C     P S   N  +T EGTG
Sbjct: 270 KFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFDSLCTVDQRPESYNPNDVITFEGTG 329

Query: 312 NPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPLS 371
           +P  C   +  +F+F +C  QE C+FDGVYQP ++G F AF+ FYYT   LNL+    L 
Sbjct: 330 DPSLCKEKVASIFDFKACHDQETCSFDGVYQPKIKGPFVAFAGFYYTASALNLSGSFSLD 389

Query: 372 TVNATIWEFCQRPWKLVEASYPGQDR-WLRDYCASGLYILTLLHEGYGFSEETWPSLEFR 430
           T N++ W FC + W  +    P  D  + R YC S  YI  L   GY F+EETWP + F 
Sbjct: 390 TFNSSTWNFCSQNWSQLPLLLPKFDEVYARSYCFSANYIYHLFVNGYKFTEETWPQIHFE 449

Query: 431 KQAGGVDIGWTLGYMLNLTGMIPADAP 457
           K+ G   I W+LGYML+LT  IPA++P
Sbjct: 450 KEVGNSSIAWSLGYMLSLTNQIPAESP 476


>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
           isoform b [Homo sapiens]
          Length = 608

 Score =  137 bits (344), Expect = 3e-32
 Identities = 127/478 (26%), Positives = 208/478 (43%), Gaps = 77/478 (16%)

Query: 30  VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVS---------QALACQV 80
           +EAT    P ++ +GIV D GSS + +F+Y W  +  N   ++          + +  ++
Sbjct: 77  IEATDTNNP-NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKI 135

Query: 81  EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
           + PGIS + ++  +  + +   L  A   +P A+H++TP ++  TAGMR+L         
Sbjct: 136 K-PGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQK--- 191

Query: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLG----------TLV 184
              A +  +L   PV F        AE+++G+ EG + WI +N+ LG           +V
Sbjct: 192 ---AILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVV 248

Query: 185 KYSFTGEWIQPP--EEMLVGALDMGGASTQITF-VPGGPILDKSTQADFRLYGSD----- 236
           + +  G         +   G LDMGG STQI + VP    + K+  A+F L G D     
Sbjct: 249 EVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTEEVAKNLLAEFNL-GCDVHQTE 307

Query: 237 --YSVYTHSYLCFG----RDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYES 290
             Y VY  ++L FG    R +   R+    +Q            L G QT L     Y  
Sbjct: 308 HVYRVYVATFLGFGGNAARQRYEDRIFANTIQKN---------RLLGKQTGLTPDMPYLD 358

Query: 291 PCVHATPPLSLPQN---LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPL-- 345
           PC+       + QN   + + GTG+   C   I+   N ++   +   + +GVYQPP+  
Sbjct: 359 PCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN---ETQTSLNGVYQPPIHF 415

Query: 346 -RGQFYAFSNFYY-TFHFLNLTSRQPLSTVNATIWEFCQRPWKLVE--------ASYPGQ 395
              +FY FS FYY T   L +      +       ++C   W ++         AS+   
Sbjct: 416 QNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADL 475

Query: 396 DRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIP 453
            R L+  C    ++  + H G+ F    + SL+   Q    ++ WTLG +L  T  +P
Sbjct: 476 HR-LKYQCFKSAWMFEVFHRGFSF-PVNYKSLKTALQVYDKEVQWTLGAILYRTRFLP 531


>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
           a [Homo sapiens]
          Length = 616

 Score =  131 bits (329), Expect = 2e-30
 Identities = 126/486 (25%), Positives = 207/486 (42%), Gaps = 85/486 (17%)

Query: 30  VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVS---------QALACQV 80
           +EAT    P ++ +GIV D GSS + +F+Y W  +  N   ++          + +  ++
Sbjct: 77  IEATDTNNP-NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKI 135

Query: 81  EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
           + PGIS + ++  +  + +   L  A   +P A+H++TP ++  TAGMR+L         
Sbjct: 136 K-PGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQK--- 191

Query: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLG----------TLV 184
              A +  +L   PV F        AE+++G+ EG + WI +N+ LG           +V
Sbjct: 192 ---AILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVV 248

Query: 185 KYSFTGEWIQPP--EEMLVGALDMGGASTQITFVPGGPILDKSTQ---------ADFRLY 233
           + +  G         +   G LDMGG STQI +     +   S+Q         A+F L 
Sbjct: 249 EVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNL- 307

Query: 234 GSD-------YSVYTHSYLCFG----RDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTL 282
           G D       Y VY  ++L FG    R +   R+    +Q            L G QT L
Sbjct: 308 GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKN---------RLLGKQTGL 358

Query: 283 ALGPLYESPCVHATPPLSLPQN---LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDG 339
                Y  PC+       + QN   + + GTG+   C   I+   N ++   +   + +G
Sbjct: 359 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN---ETQTSLNG 415

Query: 340 VYQPPL---RGQFYAFSNFYY-TFHFLNLTSRQPLSTVNATIWEFCQRPWKLVE------ 389
           VYQPP+     +FY FS FYY T   L +      +       ++C   W ++       
Sbjct: 416 VYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRG 475

Query: 390 --ASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLN 447
             AS+    R L+  C    ++  + H G+ F    + SL+   Q    ++ WTLG +L 
Sbjct: 476 LYASHADLHR-LKYQCFKSAWMFEVFHRGFSF-PVNYKSLKTALQVYDKEVQWTLGAILY 533

Query: 448 LTGMIP 453
            T  +P
Sbjct: 534 RTRFLP 539


>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
           sapiens]
          Length = 428

 Score =  124 bits (311), Expect = 2e-28
 Identities = 118/417 (28%), Positives = 179/417 (42%), Gaps = 56/417 (13%)

Query: 43  FGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESLQGC 102
           +GI+FDAGS+ T + +Y ++        ++   +   V+ PG+S++     Q  E++QG 
Sbjct: 49  YGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVK-PGLSAFVDQPKQGAETVQGL 107

Query: 103 LEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQARDIFAAVTQVLGRSP--VDFWGA 160
           LE A   IP +  +KTP  L ATAG+RLL      +A+ +   V ++  +SP  V     
Sbjct: 108 LEVAKDSIPRSHWKKTPVVLKATAGLRLLP---EHKAKALLFEVKEIFRKSPFLVPKGSV 164

Query: 161 ELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITFVPGGP 220
            ++ G  EG   W+TVN+  G L  +           +  VG LD+GGASTQITF+P   
Sbjct: 165 SIMDGSDEGILAWVTVNFLTGQLHGH----------RQETVGTLDLGGASTQITFLPQFE 214

Query: 221 ILDKSTQ----ADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLS 276
              + T       F ++ S Y +YTHSYL F           GL  +R A        L 
Sbjct: 215 KTLEQTPRGYLTSFEMFNSTYKLYTHSYLGF-----------GLKAARLAT-------LG 256

Query: 277 GYQTTLALGPLYESPCVHATPPLSLPQNLTVEGT-GNPGACVSAIRE-LFNFSSCQGQED 334
             +T    G  + S C        LP+ L  E   G         +E    F  C  +  
Sbjct: 257 ALETEGTDGHTFRSAC--------LPRWLEAEWIFGGVKYQYGGNQEGEVGFEPCYAEVL 308

Query: 335 CAFDGVYQPP---LRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEAS 391
               G    P    RG FYAFS +Y      ++   +    +    +E   R       +
Sbjct: 309 RVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLEN 368

Query: 392 YPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 448
           +     +L   C    YI  LL +G+GF++ T   L+  K+   ++ GW LG   +L
Sbjct: 369 FTSGSPFL---CMDLSYITALLKDGFGFADST--VLQLTKKVNNIETGWALGATFHL 420


>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
           sapiens]
          Length = 604

 Score =  122 bits (306), Expect = 7e-28
 Identities = 128/493 (25%), Positives = 216/493 (43%), Gaps = 76/493 (15%)

Query: 30  VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVV---------SQALACQV 80
           +EAT    P ++ +G+V D GSS + +F+Y W  +  N   ++         SQ +  ++
Sbjct: 72  LEATDTEDP-NLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLDIKQMRDRNSQPVVKKI 130

Query: 81  EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
           + PGIS+       A + L+  L  A   +P  +H++TP ++  TAGMRLL  +      
Sbjct: 131 K-PGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCTAGMRLLPERKQ---- 185

Query: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLGTL----VKYSFTG 190
              A +  ++   P++F        AE+++G+ EG + WI +N+ LG         +   
Sbjct: 186 --LAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDHEDESDAEAT 243

Query: 191 EWIQPPEEMLVGALDMGGASTQITF-VPGGPILDKSTQ--------ADFRLYGSD----- 236
           + +       VG LDMGGAS QI + VP    +  + Q        A+F L G D     
Sbjct: 244 QELAAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAAKILLAEFNL-GCDVQHTE 302

Query: 237 --YSVYTHSYLCFGRDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTLALGPLYESPCVH 294
             Y VY  ++L FG +    R    LV +      R    L G +T L+    +  PC+ 
Sbjct: 303 HVYRVYVTTFLGFGGNFARQR-YEDLVLNETLNKNR----LLGQKTGLSPDNPFLDPCL- 356

Query: 295 ATPPLSL-------PQNLTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDGVYQPPL-- 345
              P+ L        Q L V G G+  +C + +  L   S+       + +G+YQ P+  
Sbjct: 357 ---PVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSN---TSQASLNGIYQSPIDF 410

Query: 346 -RGQFYAFSNFYY-TFHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYP-------GQD 396
              +FY FS F+Y T   L +  R    T      ++C   W ++   +          +
Sbjct: 411 NNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFSSHADE 470

Query: 397 RWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIP-AD 455
             L+  C    ++  +LHEG+ F  + +P+L   +     ++ WTLG +L  T  +P  D
Sbjct: 471 HRLKYQCFKSAWMYQVLHEGFHFPYD-YPNLRTAQLVYDREVQWTLGAILYKTRFLPLRD 529

Query: 456 APAQWRAESYGVW 468
              +   +++G W
Sbjct: 530 LRQEGVRQAHGSW 542


>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 2 [Homo sapiens]
          Length = 467

 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 107/425 (25%), Positives = 182/425 (42%), Gaps = 77/425 (18%)

Query: 40  DIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESL 99
           ++ +GI+FDAGS+ T + ++Q+         +  +    +   PG+S+Y  +  ++ + +
Sbjct: 82  EVFYGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETF--KALKPGLSAYADDVEKSAQGI 139

Query: 100 QGCLEEALVLIPEAQHRKTPTFLGATAGMRLL----SRKNSSQARDIFAAVTQVLGRSPV 155
           +  L+ A   IP    + TP  L ATAG+RLL    ++K   + +++F A   ++G   V
Sbjct: 140 RELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCV 199

Query: 156 DFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITF 215
                 ++ G  EG   WIT+N+  G+L          + P    VG LD+GG STQI F
Sbjct: 200 -----SIMNGTDEGVSAWITINFLTGSL----------KTPGGSSVGMLDLGGGSTQIAF 244

Query: 216 VPGGPILDKSTQAD-------FRLYGSDYSVYTHSYLCFGRDQMLSRL-LVGLVQSRPA- 266
           +P    ++ + QA         R++   Y +Y++SYL  G   M +RL ++G V+ +PA 
Sbjct: 245 LPR---VEGTLQASPPGYLTALRMFNRTYKLYSYSYL--GLGLMSARLAILGGVEGQPAK 299

Query: 267 --ALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGA------CVS 318
               L  PC          L P ++    HA         +T   +G   A      C +
Sbjct: 300 DGKELVSPC----------LSPSFKGEWEHA--------EVTYRVSGQKAAASLHELCAA 341

Query: 319 AIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIW 378
            + E+      + +E    D          FYAFS +Y     + L   +   ++    +
Sbjct: 342 RVSEVLQNRVHRTEEVKHVD----------FYAFSYYYDLAAGVGLIDAEKGGSLVVGDF 391

Query: 379 EFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDI 438
           E      K V  +   Q +     C    Y+  LL E +GF       L+  ++   V+ 
Sbjct: 392 EIAA---KYVCRTLETQPQSSPFSCMDLTYVSLLLQE-FGFPRS--KVLKLTRKIDNVET 445

Query: 439 GWTLG 443
            W LG
Sbjct: 446 SWALG 450


>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
           isoform 1 [Homo sapiens]
          Length = 484

 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 107/425 (25%), Positives = 182/425 (42%), Gaps = 77/425 (18%)

Query: 40  DIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVSQALACQVEGPGISSYTSNAAQAGESL 99
           ++ +GI+FDAGS+ T + ++Q+         +  +    +   PG+S+Y  +  ++ + +
Sbjct: 99  EVFYGIMFDAGSTGTRVHVFQFTRPPRETPTLTHETF--KALKPGLSAYADDVEKSAQGI 156

Query: 100 QGCLEEALVLIPEAQHRKTPTFLGATAGMRLL----SRKNSSQARDIFAAVTQVLGRSPV 155
           +  L+ A   IP    + TP  L ATAG+RLL    ++K   + +++F A   ++G   V
Sbjct: 157 RELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQKVKEVFKASPFLVGDDCV 216

Query: 156 DFWGAELLAGQAEGAFGWITVNYGLGTLVKYSFTGEWIQPPEEMLVGALDMGGASTQITF 215
                 ++ G  EG   WIT+N+  G+L          + P    VG LD+GG STQI F
Sbjct: 217 -----SIMNGTDEGVSAWITINFLTGSL----------KTPGGSSVGMLDLGGGSTQIAF 261

Query: 216 VPGGPILDKSTQAD-------FRLYGSDYSVYTHSYLCFGRDQMLSRL-LVGLVQSRPA- 266
           +P    ++ + QA         R++   Y +Y++SYL  G   M +RL ++G V+ +PA 
Sbjct: 262 LPR---VEGTLQASPPGYLTALRMFNRTYKLYSYSYL--GLGLMSARLAILGGVEGQPAK 316

Query: 267 --ALLRHPCYLSGYQTTLALGPLYESPCVHATPPLSLPQNLTVEGTGNPGA------CVS 318
               L  PC          L P ++    HA         +T   +G   A      C +
Sbjct: 317 DGKELVSPC----------LSPSFKGEWEHA--------EVTYRVSGQKAAASLHELCAA 358

Query: 319 AIRELFNFSSCQGQEDCAFDGVYQPPLRGQFYAFSNFYYTFHFLNLTSRQPLSTVNATIW 378
            + E+      + +E    D          FYAFS +Y     + L   +   ++    +
Sbjct: 359 RVSEVLQNRVHRTEEVKHVD----------FYAFSYYYDLAAGVGLIDAEKGGSLVVGDF 408

Query: 379 EFCQRPWKLVEASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDI 438
           E      K V  +   Q +     C    Y+  LL E +GF       L+  ++   V+ 
Sbjct: 409 EIAA---KYVCRTLETQPQSSPFSCMDLTYVSLLLQE-FGFPRS--KVLKLTRKIDNVET 462

Query: 439 GWTLG 443
            W LG
Sbjct: 463 SWALG 467


>gi|188497667 trafficking protein, kinesin binding 2 [Homo sapiens]
          Length = 914

 Score = 30.0 bits (66), Expect = 5.0
 Identities = 11/34 (32%), Positives = 17/34 (50%)

Query: 297 PPLSLPQNLTVEGTGNPGACVSAIRELFNFSSCQ 330
           PP++         T NPG C+S     F F++C+
Sbjct: 644 PPITSAGGPVTVATANPGKCLSCTNSTFTFTTCR 677


>gi|22748751 solute carrier family 43, member 2 [Homo sapiens]
          Length = 569

 Score = 29.6 bits (65), Expect = 6.6
 Identities = 33/124 (26%), Positives = 52/124 (41%), Gaps = 26/124 (20%)

Query: 158 WGAELLAGQAEGAFGWITV---NYGLGTL--------VKYSFTGEWI--QPPEEMLVGAL 204
           WG+ L+  ++EG + ++     N   GT+         + S+   W+  Q  +EML  A 
Sbjct: 33  WGSLLIMLKSEGFYSYLCTEPENVTNGTVGGTAEPGHEEVSWMNGWLSCQAQDEMLNLAF 92

Query: 205 DMGGASTQITFVPGGPILDKSTQADFRLYGSDYSVYTHSYLCFGRDQMLSRLLVGLVQSR 264
            +G        +P G ++DK      RL GS          CF     +S LL+    S+
Sbjct: 93  TVGSFLLSAITLPLGIVMDKYGPRKLRLLGS---------ACFA----VSCLLIAYGASK 139

Query: 265 PAAL 268
           P AL
Sbjct: 140 PNAL 143


>gi|196123591 cytochrome b [Homo sapiens neanderthalensis]
          Length = 378

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 14/98 (14%)

Query: 397 RWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNLTGMIPA-- 454
           R+L    AS  +I   LH G G     + S  + K        W +G +L L  M  A  
Sbjct: 80  RYLHANGASMFFICLFLHIGRGLY---YGSFLYSKT-------WNIGIILLLATMATAFM 129

Query: 455 DAPAQWRAESYGVWVAKVVFMVLALVAVVGAALVQLFW 492
                W   S+  W A V+  +L+ +  +G  LVQ  W
Sbjct: 130 GYVLPWGQMSF--WGATVITNLLSAIPYIGTDLVQWIW 165


>gi|61743914 cholinergic receptor, nicotinic, gamma polypeptide
           precursor [Homo sapiens]
          Length = 517

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 8/67 (11%)

Query: 54  TSLFLYQWLANKENGTGVVSQALACQVEGP--GISSYTSNAAQAGESLQGCLEEALVLIP 111
           + L   QW        G+V+ AL    +GP  G+S +  +  QA  ++Q C+ EA  LI 
Sbjct: 396 SELLFQQWQRQ-----GLVAAALEKLEKGPELGLSQFCGSLKQAAPAIQACV-EACNLIA 449

Query: 112 EAQHRKT 118
            A+H+++
Sbjct: 450 CARHQQS 456


>gi|224451116 Mu-2 related death-inducing protein [Homo sapiens]
          Length = 490

 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/115 (24%), Positives = 47/115 (40%), Gaps = 11/115 (9%)

Query: 294 HATPPLSLPQNLTVEGTGNPGACVSAIRE-LFNFSSCQGQEDCAFDGVYQPPLRGQFYAF 352
           + T  LSLP N +         CV+++   +   SS    +D AF G Y+ P      +F
Sbjct: 249 NVTISLSLPTNGSPLQDILVHPCVTSLDSAILTSSSIDAMDDSAFSGPYKFPFTPPLESF 308

Query: 353 SNFYYT----------FHFLNLTSRQPLSTVNATIWEFCQRPWKLVEASYPGQDR 397
           +  +YT          F+ +     Q   T+N  + E  +  ++  EA  P  +R
Sbjct: 309 NLCFYTSQVPVPPILGFYQMKEEEVQLRITINLKLHESVKNNFEFCEAHIPFYNR 363


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,510,883
Number of Sequences: 37866
Number of extensions: 892085
Number of successful extensions: 1830
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1757
Number of HSP's gapped (non-prelim): 23
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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