Search of human proteins with 109452583

Search of human proteins with 109452583

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|109452583 coiled-coil and C2 domain containing 2B isoform 2
[Homo sapiens]
         (322 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|109452583 coiled-coil and C2 domain containing 2B isoform 2 [...   670   0.0  
gi|229577352 coiled-coil and C2 domain containing 2B isoform 1 [...   544   e-155
gi|197209817 coiled-coil and C2 domain containing 2A isoform b [...   239   2e-63
gi|197209974 coiled-coil and C2 domain containing 2A isoform a [...   219   3e-57
gi|21314728 centrosomal protein 76kDa [Homo sapiens]                   57   3e-08

>gi|109452583 coiled-coil and C2 domain containing 2B isoform 2
           [Homo sapiens]
          Length = 322

 Score =  670 bits (1728), Expect = 0.0
 Identities = 322/322 (100%), Positives = 322/322 (100%)

Query: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60
           MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA
Sbjct: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60

Query: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120
           MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP
Sbjct: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120

Query: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV
Sbjct: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240
           VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE
Sbjct: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240

Query: 241 SFWKQLLPKNVQGTKIQSIQVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVY 300
           SFWKQLLPKNVQGTKIQSIQVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVY
Sbjct: 241 SFWKQLLPKNVQGTKIQSIQVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVY 300

Query: 301 IHPYPNNILSVWVYLASLVQHQ 322
           IHPYPNNILSVWVYLASLVQHQ
Sbjct: 301 IHPYPNNILSVWVYLASLVQHQ 322


>gi|229577352 coiled-coil and C2 domain containing 2B isoform 1
           [Homo sapiens]
          Length = 401

 Score =  544 bits (1401), Expect = e-155
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60
           MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA
Sbjct: 1   MMTEKHEDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTEVLQRAQIFKKNCKA 60

Query: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120
           MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP
Sbjct: 61  MFPNRRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVP 120

Query: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV
Sbjct: 121 NTPDENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180

Query: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240
           VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE
Sbjct: 181 VTQETNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKE 240

Query: 241 SFWKQLLPKNVQGTKIQSIQ 260
           SFWKQLLPKNVQGTKIQSIQ
Sbjct: 241 SFWKQLLPKNVQGTKIQSIQ 260



 Score =  131 bits (329), Expect = 9e-31
 Identities = 63/67 (94%), Positives = 64/67 (95%)

Query: 256 IQSIQVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL 315
           +Q   VTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL
Sbjct: 335 LQFYWVTGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYL 394

Query: 316 ASLVQHQ 322
           ASLVQHQ
Sbjct: 395 ASLVQHQ 401


>gi|197209817 coiled-coil and C2 domain containing 2A isoform b [Homo
            sapiens]
          Length = 1512

 Score =  239 bits (611), Expect = 2e-63
 Identities = 111/256 (43%), Positives = 164/256 (64%), Gaps = 2/256 (0%)

Query: 7    EDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQSEFLDQTE--VLQRAQIFKKNCKAMFPN 64
            ED   +    H+ I ++WLGC+  PFS +  Q+ F  Q +  +LQ  + F+  C   FPN
Sbjct: 1116 EDDRERGSGIHTRIERHWLGCVKMPFSTIYFQARFESQEDEKLLQATEKFQAECALKFPN 1175

Query: 65   RRIVTTVFNDEGIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPD 124
            R+ +TTV +  G    +TRY+K LNPPQ+LL+++ +N  AT +L+AR+VSLIPF+P+T  
Sbjct: 1176 RQCLTTVIDISGKTVFITRYLKPLNPPQELLNVYPNNLQATAELVARYVSLIPFLPDTVS 1235

Query: 125  ENDGSDIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYVVTQE 184
                 D+W TS+  + L  G++EEHA+LLCN+FL  GKKA +L+G ++ EG  AYV+T E
Sbjct: 1236 FGGICDLWSTSDQFLDLLAGDEEEHAVLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWE 1295

Query: 185  TNEYLLWNPSTGQCYKQFDPFCPLKSVDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWK 244
               YL+WNP +G  Y QFD FCPLK+V CL    N+WFNIQ+  +P+ + FD ++   WK
Sbjct: 1296 QGRYLIWNPCSGHFYGQFDTFCPLKNVGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWK 1355

Query: 245  QLLPKNVQGTKIQSIQ 260
                +++    + S+Q
Sbjct: 1356 SFFSRSLPYPGLSSVQ 1371



 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 37/61 (60%), Positives = 52/61 (85%)

Query: 262  TGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQH 321
            +GFP+ MPY +V+ +IDAVY TG+H+ + P  EFALAVYIHPYP N+LSVW+Y+ASL+++
Sbjct: 1452 SGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRN 1511

Query: 322  Q 322
            +
Sbjct: 1512 R 1512


>gi|197209974 coiled-coil and C2 domain containing 2A isoform a [Homo
            sapiens]
          Length = 1620

 Score =  219 bits (557), Expect = 3e-57
 Identities = 99/230 (43%), Positives = 150/230 (65%)

Query: 31   PFSALLQQSEFLDQTEVLQRAQIFKKNCKAMFPNRRIVTTVFNDEGIQFLVTRYIKALNP 90
            P  ++ ++ E  +  ++LQ  + F+  C   FPNR+ +TTV +  G    +TRY+K LNP
Sbjct: 1250 PGESIREKFESQEDEKLLQATEKFQAECALKFPNRQCLTTVIDISGKTVFITRYLKPLNP 1309

Query: 91   PQQLLDIFLHNSNATFDLIARFVSLIPFVPNTPDENDGSDIWMTSEHCISLAIGNKEEHA 150
            PQ+LL+++ +N  AT +L+AR+VSLIPF+P+T       D+W TS+  + L  G++EEHA
Sbjct: 1310 PQELLNVYPNNLQATAELVARYVSLIPFLPDTVSFGGICDLWSTSDQFLDLLAGDEEEHA 1369

Query: 151  ILLCNFFLYFGKKALVLLGTSVLEGHVAYVVTQETNEYLLWNPSTGQCYKQFDPFCPLKS 210
            +LLCN+FL  GKKA +L+G ++ EG  AYV+T E   YL+WNP +G  Y QFD FCPLK+
Sbjct: 1370 VLLCNYFLSLGKKAWLLMGNAIPEGPTAYVLTWEQGRYLIWNPCSGHFYGQFDTFCPLKN 1429

Query: 211  VDCLFDDRNVWFNIQQNNTPMAVFFDYSKESFWKQLLPKNVQGTKIQSIQ 260
            V CL    N+WFNIQ+  +P+ + FD ++   WK    +++    + S+Q
Sbjct: 1430 VGCLIGPDNIWFNIQRYESPLRINFDVTRPKLWKSFFSRSLPYPGLSSVQ 1479



 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 37/61 (60%), Positives = 52/61 (85%)

Query: 262  TGFPIQMPYIDVQSIIDAVYQTGIHSAEFPQTEFALAVYIHPYPNNILSVWVYLASLVQH 321
            +GFP+ MPY +V+ +IDAVY TG+H+ + P  EFALAVYIHPYP N+LSVW+Y+ASL+++
Sbjct: 1560 SGFPLHMPYSEVKPLIDAVYSTGVHNIDVPNVEFALAVYIHPYPKNVLSVWIYVASLIRN 1619

Query: 322  Q 322
            +
Sbjct: 1620 R 1620



 Score = 30.4 bits (67), Expect = 2.2
 Identities = 12/33 (36%), Positives = 19/33 (57%)

Query: 7    EDHCLKSCSGHSYIRKNWLGCIVFPFSALLQQS 39
            ED   +    H+ I ++WLGC+  PFS +  Q+
Sbjct: 1165 EDDRERGSGIHTRIERHWLGCVKMPFSTIYFQA 1197


>gi|21314728 centrosomal protein 76kDa [Homo sapiens]
          Length = 659

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 57/200 (28%), Positives = 87/200 (43%), Gaps = 27/200 (13%)

Query: 64  NRRIVTTVFNDE-GIQFLVTRYIKALNPPQQLLDIFLHNSNATFDLIARFVSLIPFVPNT 122
           N R+V     DE GI   V  Y+K L   + LLD        T    ARFV+++ +    
Sbjct: 302 NSRLVKIFAQDENGINRPVCSYVKPLRAGR-LLD--------TPRQAARFVNVLGY-ERA 351

Query: 123 PDENDGS--DIWMTSEHCISLAIGNKEEHAILLCNFFLYFGKKALVLLGTSVLEGHVAYV 180
           P    G   + W T    +    G+ E+HA LLC+  L +G +A V +GT       A+V
Sbjct: 352 PVIGGGGKQEQWCTLLAFLCRNKGDCEDHANLLCSLLLGYGLEAFVCVGTKAKGVPHAWV 411

Query: 181 VTQETNEYL-LWNPSTGQCY-------------KQFDPFCPLKSVDCLFDDRNVWFNIQQ 226
           +T  T+  +  W   TG  Y             +Q  P  P +++ C+F+ +    N Q 
Sbjct: 412 MTCGTDGAITFWESLTGHRYIHKPTNPDEPPVAEQPKPLYPYRTIGCVFNHQMFLGNCQP 471

Query: 227 NNTPMAVFFDYSKESFWKQL 246
           ++      FD + ES WK +
Sbjct: 472 SDAVETCVFDLNDESKWKPM 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,063,565
Number of Sequences: 37866
Number of extensions: 496165
Number of successful extensions: 1129
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 1117
Number of HSP's gapped (non-prelim): 10
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.