BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|8659555 aconitase 1 [Homo sapiens] (889 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|8659555 aconitase 1 [Homo sapiens] 1791 0.0 gi|41352693 iron-responsive element binding protein 2 [Homo sapi... 1030 0.0 gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens] 207 3e-53 gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 30 7.6 gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] 30 7.6 gi|18105054 kinesin-associated protein 3 [Homo sapiens] 30 10.0 >gi|8659555 aconitase 1 [Homo sapiens] Length = 889 Score = 1791 bits (4638), Expect = 0.0 Identities = 889/889 (100%), Positives = 889/889 (100%) Query: 1 MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI 60 MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI Sbjct: 1 MSNPFAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDI 60 Query: 61 ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA 120 ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA Sbjct: 61 ENILHWNVTQHKNIEVPFKPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPA 120 Query: 121 DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV 180 DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV Sbjct: 121 DLVIDHSIQVDFNRRADSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQV 180 Query: 181 NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP 240 NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP Sbjct: 181 NLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLP 240 Query: 241 QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC 300 QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC Sbjct: 241 QVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMC 300 Query: 301 PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE 360 PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE Sbjct: 301 PEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVE 360 Query: 361 LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT 420 LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT Sbjct: 361 LDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNT 420 Query: 421 EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY 480 EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY Sbjct: 421 EFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTY 480 Query: 481 YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG 540 YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG Sbjct: 481 YLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEG 540 Query: 541 RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE 600 RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE Sbjct: 541 RVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVE 600 Query: 601 RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK 660 RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK Sbjct: 601 RQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLDLQPPK 660 Query: 661 SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA 720 SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA Sbjct: 661 SIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMA 720 Query: 721 RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR 780 RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR Sbjct: 721 RGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSR 780 Query: 781 DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP 840 DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP Sbjct: 781 DWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIP 840 Query: 841 ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK 889 ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK Sbjct: 841 ENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMAK 889 >gi|41352693 iron-responsive element binding protein 2 [Homo sapiens] Length = 963 Score = 1030 bits (2663), Expect = 0.0 Identities = 517/957 (54%), Positives = 686/957 (71%), Gaps = 76/957 (7%) Query: 5 FAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENIL 64 F +L E L+ KKFF+++KL ++Y LP+SIRVLLEAA+RNCD FL+KK+D+ NIL Sbjct: 10 FEYLIETLND-SSHKKFFDVSKL-GTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNIL 67 Query: 65 HWNVTQHKNIE-------------------VPFKPARVILQDFTGVPAVV---------- 95 W T+ N+E V F R ++ G P V Sbjct: 68 DWK-TKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTV 126 Query: 96 ------DFA--AMRDAVKKLGGDPEKINPVCPADL------------------------- 122 DF+ A+++A GGD +K + P + Sbjct: 127 DHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRN 186 Query: 123 -------VIDHSIQVDFNRRA----DSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIP 171 + + I F+ + +++ KNQ++EF RNRER +F KW S+ F N+ +IP Sbjct: 187 SGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIP 246 Query: 172 PGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVML 231 PG+G+ HQ+NLEYL+RVVF++ +PDS+VGTDSH TM++GLGILGWGVGGIE EAVML Sbjct: 247 PGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVML 306 Query: 232 GQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIA 291 G P+S+ LP+V+G L G +P VTS D+VL ITKHLRQVGV GKFVEFFG GV+QLSI Sbjct: 307 GLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIV 366 Query: 292 DRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQ 351 DR TIANMCPEYGA +FFPVD V++ +L TG + KL+ ++ YL+AV +FR+ + S Sbjct: 367 DRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSG 426 Query: 352 DPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHND 411 +P+++QV++++L ++VP SGPKRPQD+VAV+DMK DF++CL K GFKGFQ+A E D Sbjct: 427 EPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKD 486 Query: 412 HKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSL 471 + Y+ +E+ L+HGSVVIAA+ SCTN NPSVML AGLLAKKAV+AGL V PYI+TSL Sbjct: 487 IVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSL 546 Query: 472 SPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGV 531 SPGSG+VT+YL SGV+PYLS+LGF++VGYGC TC+GN+ PL + V+ A+ QGDLV G+ Sbjct: 547 SPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGDLVTCGI 606 Query: 532 LSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWP 591 LSGN+NFEGR+ RANYLASPPLV+AYAIAGT+ IDF+ EPLG + G+ ++L DIWP Sbjct: 607 LSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLHDIWP 666 Query: 592 TRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFEN 651 +R+E+ VE ++VI MFK + KIE N+ WN+L P LF W+ KSTYI+ P FF+ Sbjct: 667 SREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDK 726 Query: 652 LTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGS 711 LT + ++I +A+VLL LGDSVTTDHISPAG+IARNS AA+YLTNRGLTPREFNSYG+ Sbjct: 727 LTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGA 786 Query: 712 RRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAG 771 RRGNDAVM RGTFANI+L N+F+ K AP+TIH PSG+ LDVF+AAE YQ+ G+PLI+LAG Sbjct: 787 RRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAG 846 Query: 772 KEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTG 831 K+YG+G+SRDWAAKGP+LLG+KAVLAESYE+IH+ +L+G+G+ PL++LPGENAD+LGL+G Sbjct: 847 KKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSG 906 Query: 832 QERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMA 888 +E +++ PE L P + + ++ TGK F + F+ DVE+T + +GG+LN++ RK + Sbjct: 907 RETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS 963 >gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens] Length = 780 Score = 207 bits (527), Expect = 3e-53 Identities = 226/816 (27%), Positives = 355/816 (43%), Gaps = 143/816 (17%) Query: 79 KPARVILQDFTGVPAVVDFAAMRDAVKKLGGDPEKINPVCPADLVIDHSIQVDFNRRADS 138 +P RV +QD T A++ F + + K+ P+ + DH I+ D Sbjct: 92 RPDRVAMQDATAQMAMLQFIS--SGLSKVA---------VPSTIHCDHLIEAQVGGEKD- 139 Query: 139 LQKNQDLEFERNRERFEFLKWGSQAFHNMRIIPPGSGIIHQVNLEYLARVVFDQDGYYYP 198 L++ +D+ N+E + FL A + + PGSGIIHQ+ LE Y YP Sbjct: 140 LRRAKDI----NQEVYNFLATAG-AKYGVGFWKPGSGIIHQIILE----------NYAYP 184 Query: 199 DSL-VGTDSHTTMIDGLGILGWGVGGIEAEAVMLGQPISMVLPQVIGYRLMGKPHPLVTS 257 L +GTDSHT GLG + GVGG +A VM G P + P+VIG +L G + Sbjct: 185 GVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWSSP 244 Query: 258 TDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIADRATIANMCPEYGATAAFFPVDEVSI 317 D++L + L G G VE+ GPGV +S ATI NM E GAT + FP + Sbjct: 245 KDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHRMK 304 Query: 318 TYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQDPDFTQVVELDLKTVVPCCSGPKRPQ 377 YL +TGR++ F+D P + Q++E++L + P +GP P Sbjct: 305 KYLSKTGRED--------IANLADEFKDHLVPDPGCHYDQLIEINLSELKPHINGPFTPD 356 Query: 378 DKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHNDHKTFIYDNTEFTLAHGSVVIAAITSC 437 V+++ K + K+G+ + + I SC Sbjct: 357 LAHPVAEVGK-----VAEKEGWP--------------------------LDIRVGLIGSC 385 Query: 438 TNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSLSPGSGVVTYYLQESGVMPYLSQLGFD 497 TN+S + A +AK+A+ GL + +++PGS + ++ G L LG Sbjct: 386 TNSSYEDMGRSAA-VAKQALAHGLKCKS--QFTITPGSEQIRATIERDGYAQILRDLGGI 442 Query: 498 VVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGVLSGNRNFEGR--VHPNTRANYLASPP 555 V+ C CIG + I +G+ + V S NRNF GR +P T A ++ SP Sbjct: 443 VLANACGPCIGQWDR------KDIKKGEKNTI-VTSYNRNFTGRNDANPETHA-FVTSPE 494 Query: 556 LVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVERQYVIPGMFKEVYQK 615 +V A AIAGT++ + E + L G++ L+ P DE+ E PG ++ YQ Sbjct: 495 IVTALAIAGTLKFNPETDYL-TGTDGKKFRLEA--PDADELPKGEFD---PG--QDTYQH 546 Query: 616 IETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTL----DLQPPKSIVDAYVLLNL 671 P D S ++ P + L L D K + D +L+ + Sbjct: 547 ------------PPKD------SSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKV 588 Query: 672 GDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGSRRGNDAVMARGTFANIRLLN 731 TTDHIS AG + F + N+ ++ NI Sbjct: 589 KGKCTTDHISAAGPWLK-----------------FRGHLDNISNNLLIGA---INIE--- 625 Query: 732 RFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAGKEYGAGSSRDWAAKGPFLLG 791 N +A + + E V D A Y++ G+ +V+ + YG GSSR+ AA P LG Sbjct: 626 ---NGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIGDENYGEGSSREHAALEPRHLG 682 Query: 792 IKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTGQERYTIIIPENLKP--QMKV 849 +A++ +S+ RIH +NL G++PL + + AD + ++ TI ++ P +K Sbjct: 683 GRAIITKSFARIHETNLKKQGLLPLTF--ADPADYNKIHPVDKLTIQGLKDFTPGKPLKC 740 Query: 850 QVKLDTGKTFQAVMRFDT--DVELTYFLNGGILNYM 883 +K G T + ++ T + ++ +F G LN M Sbjct: 741 IIKHPNG-TQETILLNHTFNETQIEWFRAGSALNRM 775 >gi|194306629 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] Length = 960 Score = 30.4 bits (67), Expect = 7.6 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 820 PGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVM--RFDTDVELTYFLNG 877 PG+ L E+ +++PE L P +K V +D FQA + F+ + TY G Sbjct: 133 PGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD----FQAKLGDGFEGFYKSTYRTLG 188 Query: 878 G 878 G Sbjct: 189 G 189 >gi|11641261 endoplasmic reticulum aminopeptidase 2 [Homo sapiens] Length = 960 Score = 30.4 bits (67), Expect = 7.6 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 6/61 (9%) Query: 820 PGENADALGLTGQERYTIIIPENLKPQMKVQVKLDTGKTFQAVM--RFDTDVELTYFLNG 877 PG+ L E+ +++PE L P +K V +D FQA + F+ + TY G Sbjct: 133 PGKELKVLSYPAHEQIALLVPEKLTPHLKYYVAMD----FQAKLGDGFEGFYKSTYRTLG 188 Query: 878 G 878 G Sbjct: 189 G 189 >gi|18105054 kinesin-associated protein 3 [Homo sapiens] Length = 792 Score = 30.0 bits (66), Expect = 10.0 Identities = 31/134 (23%), Positives = 55/134 (41%), Gaps = 18/134 (13%) Query: 542 VHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWPTRDEIQAVER 601 VHP+ +A L++ Y + TI + LG + Q++ +I ++ R Sbjct: 20 VHPSEKA-------LIVHYEVEATILGEMGDPMLGERKECQKIIRLKSLNANTDITSLAR 72 Query: 602 QYVI------PGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFENLTLD 655 + V P EV Q + + ++L+ K KS+ K PP FE + +D Sbjct: 73 KVVEECKLIHPSKLNEVEQLLYYLQNRRDSLSGKEKK-----EKSSKPKDPPPFEGMEID 127 Query: 656 LQPPKSIVDAYVLL 669 + +D Y+ L Sbjct: 128 EVANINDMDEYIEL 141 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.138 0.411 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,448,444 Number of Sequences: 37866 Number of extensions: 1577852 Number of successful extensions: 2992 Number of sequences better than 10.0: 6 Number of HSP's better than 10.0 without gapping: 3 Number of HSP's successfully gapped in prelim test: 3 Number of HSP's that attempted gapping in prelim test: 2980 Number of HSP's gapped (non-prelim): 9 length of query: 889 length of database: 18,247,518 effective HSP length: 111 effective length of query: 778 effective length of database: 14,044,392 effective search space: 10926536976 effective search space used: 10926536976 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.