Guide to the Human Genome
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Search of human proteins with 85067507

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|85067507 CCR4-NOT transcription complex, subunit 7 isoform 1
[Homo sapiens]
         (285 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|85067507 CCR4-NOT transcription complex, subunit 7 isoform 1 ...   586   e-168
gi|85067505 CCR4-NOT transcription complex, subunit 7 isoform 2 ...   497   e-141
gi|31542315 CCR4-NOT transcription complex, subunit 8 [Homo sapi...   456   e-129
gi|156564398 target of EGR1, member 1 (nuclear) [Homo sapiens]         37   0.020
gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease...    32   0.83 

>gi|85067507 CCR4-NOT transcription complex, subunit 7 isoform 1
           [Homo sapiens]
          Length = 285

 Score =  586 bits (1510), Expect = e-168
 Identities = 285/285 (100%), Positives = 285/285 (100%)

Query: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60
           MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY
Sbjct: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120
           QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120

Query: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180
           IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD
Sbjct: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180

Query: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240
           FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK
Sbjct: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240

Query: 241 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS 285
           MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS
Sbjct: 241 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEEANKQS 285


>gi|85067505 CCR4-NOT transcription complex, subunit 7 isoform 2
           [Homo sapiens]
          Length = 244

 Score =  497 bits (1280), Expect = e-141
 Identities = 243/244 (99%), Positives = 244/244 (100%)

Query: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60
           MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY
Sbjct: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120
           QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120

Query: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180
           IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD
Sbjct: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180

Query: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240
           FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK
Sbjct: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240

Query: 241 MREM 244
           MRE+
Sbjct: 241 MREV 244


>gi|31542315 CCR4-NOT transcription complex, subunit 8 [Homo
           sapiens]
          Length = 292

 Score =  456 bits (1174), Expect = e-129
 Identities = 215/280 (76%), Positives = 251/280 (89%)

Query: 1   MPAATVDHSQRICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADY 60
           MPAA V++SQ ICEVWA NL+EEM+KIR+++  Y+Y+AMDTEFPGVV RPIGEFRS+ DY
Sbjct: 1   MPAALVENSQVICEVWASNLEEEMRKIREIVLSYSYIAMDTEFPGVVVRPIGEFRSSIDY 60

Query: 61  QYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSG 120
           QYQLLRCNVDLLKIIQLGLTF NE+GEYP G +TWQFNFKFNLTEDMY+QDSI+LL  SG
Sbjct: 61  QYQLLRCNVDLLKIIQLGLTFTNEKGEYPSGINTWQFNFKFNLTEDMYSQDSIDLLANSG 120

Query: 121 IQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSGYDFGYLIKILTNSNLPEEELD 180
           +QF+KHEEEGI+T +FAELLMTSGVVLC+ VKWLSFHSGYDFGY++K+LT+S LPEEE +
Sbjct: 121 LQFQKHEEEGIDTLHFAELLMTSGVVLCDNVKWLSFHSGYDFGYMVKLLTDSRLPEEEHE 180

Query: 181 FFEILRLFFPVIYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLTGMAFFK 240
           FF IL LFFP IYDVKYLMKSCKNLKGGLQEVA+QL+L+RIG QHQAGSDSLLTGMAFF+
Sbjct: 181 FFHILNLFFPSIYDVKYLMKSCKNLKGGLQEVADQLDLQRIGRQHQAGSDSLLTGMAFFR 240

Query: 241 MREMFFEDHIDDAKYCGHLYGLGSGSSYVQNGTGNAYEEE 280
           M+E+FFED IDDAKYCG LYGLG+G +  QN   ++ +E+
Sbjct: 241 MKELFFEDSIDDAKYCGRLYGLGTGVAQKQNEDVDSAQEK 280


>gi|156564398 target of EGR1, member 1 (nuclear) [Homo sapiens]
          Length = 510

 Score = 37.0 bits (84), Expect = 0.020
 Identities = 63/257 (24%), Positives = 98/257 (38%), Gaps = 27/257 (10%)

Query: 12  ICEVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDL 71
           + +V + N  E    +   I+  N+VA+DTE  G+  R         + +Y+ +      
Sbjct: 36  VVDVQSNNFKEMWPSLLLAIKTANFVAVDTELSGLGDRK-SLLNQCIEERYKAVCHAART 94

Query: 72  LKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLT-----EDMYAQDSIELLT--------- 117
             I+ LGL     Q +    +   Q    FNLT     E +    S++ L          
Sbjct: 95  RSILSLGLACFKRQPDKGEHSYLAQV---FNLTLLCMEEYVIEPKSVQFLIQHGFNFNQQ 151

Query: 118 -TSGIQFKKHEEEGIETQYFAELLMTSGVVLCEGVKWLSFHSG-YDFGYLIKILTNSNLP 175
              GI + K  ++G E+Q  ++ + T  + L    + L  H+G  D  +L +    ++LP
Sbjct: 152 YAQGIPYHKGNDKGDESQ--SQSVRTLFLELIRARRPLVLHNGLIDLVFLYQNF-YAHLP 208

Query: 176 EEELDFFEILRLFFPV-IYDVKYLMKSCKNLKGGLQEVAEQLELERIGPQHQAGSDSLLT 234
           E    F   L   FP  IYD KY  +          E A +      G Q  AGS  L  
Sbjct: 209 ESLGTFTADLCEMFPAGIYDTKYAAEFHARFVASYLEYAFRKCERENGKQRAAGSPHLTL 268

Query: 235 GMAFFKMREMFFEDHID 251
               +        DHID
Sbjct: 269 EFCNYPSS---MRDHID 282


>gi|4505611 poly(A)-specific ribonuclease (deadenylation nuclease)
           isoform 1 [Homo sapiens]
          Length = 639

 Score = 31.6 bits (70), Expect = 0.83
 Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 12/130 (9%)

Query: 14  EVWACNLDEEMKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNA----DYQYQLLRCNV 69
           E+   N    + K+ Q I + ++ A+D EF G+   P     +N     + +YQ L+ + 
Sbjct: 2   EIIRSNFKSNLHKVYQAIEEADFFAIDGEFSGISDGPSVSALTNGFDTPEERYQKLKKHS 61

Query: 70  DLLKIIQLGL-TFMNEQGEYPPGTSTWQFNF---KFNLTED----MYAQDSIELLTTSGI 121
               + Q GL TF  +  +    T ++ F      FN +      +    SI+ L + G 
Sbjct: 62  MDFLLFQFGLCTFKYDYTDSKYITKSFNFYVFPKPFNRSSPDVKFVCQSSSIDFLASQGF 121

Query: 122 QFKKHEEEGI 131
            F K    GI
Sbjct: 122 DFNKVFRNGI 131


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,082,018
Number of Sequences: 37866
Number of extensions: 464524
Number of successful extensions: 937
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 933
Number of HSP's gapped (non-prelim): 6
length of query: 285
length of database: 18,247,518
effective HSP length: 101
effective length of query: 184
effective length of database: 14,423,052
effective search space: 2653841568
effective search space used: 2653841568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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