Search of human proteins with 84798622

Search of human proteins with 84798622

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|84798622 mannosidase, beta A, lysosomal [Homo sapiens]
         (879 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|84798622 mannosidase, beta A, lysosomal [Homo sapiens]            1828   0.0  
gi|4504223 glucuronidase, beta [Homo sapiens]                          49   2e-05
gi|54859722 nucleoporin 160kDa [Homo sapiens]                          32   3.4  
gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]                       30   7.5  
gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]                       30   7.5  
gi|28882043 TR4 orphan receptor associated protein TRA16 [Homo s...    30   7.5  
gi|120953264 folliculin interacting protein 1 isoform 2 [Homo sa...    30   9.8  
gi|120953291 folliculin interacting protein 1 isoform 1 [Homo sa...    30   9.8  

>gi|84798622 mannosidase, beta A, lysosomal [Homo sapiens]
          Length = 879

 Score = 1828 bits (4734), Expect = 0.0
 Identities = 879/879 (100%), Positives = 879/879 (100%)

Query: 1   MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD 60
           MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD
Sbjct: 1   MRLHLLLLLALCGAGTTAAELSYSLRGNWSICNGNGSLELPGAVPGCVHSALFQQGLIQD 60

Query: 61  SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD 120
           SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD
Sbjct: 61  SYYRFNDLNYRWVSLDNWTYSKEFKIPFEISKWQKVNLILEGVDTVSKILFNEVTIGETD 120

Query: 121 NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF 180
           NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF
Sbjct: 121 NMFNRYSFDITNVVRDVNSIELRFQSAVLYAAQQSKAHTRYQVPPDCPPLVQKGECHVNF 180

Query: 181 VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD 240
           VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD
Sbjct: 181 VRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQEWNLEIESTFD 240

Query: 241 VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG 300
           VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG
Sbjct: 241 VVSSKPVGGQVIVAIPKLQTQQTYSIELQPGKRIVELFVNISKNITVETWWPHGHGNQTG 300

Query: 301 YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA 360
           YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA
Sbjct: 301 YNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKINGFPIFLKGSNWIPA 360

Query: 361 DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA 420
           DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA
Sbjct: 361 DSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQDEFYELCDELGIMVWQDFMFACA 420

Query: 421 LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD 480
           LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD
Sbjct: 421 LYPTDQGFLDSVTAEVAYQIKRLKSHPSIIIWSGNNENEEALMMNWYHISFTDRPIYIKD 480

Query: 481 YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC 540
           YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC
Sbjct: 481 YVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVAEAWVSQNPNSNYFGDVHFYDYISDC 540

Query: 541 WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG 600
           WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG
Sbjct: 541 WNWKVFPKARFASEYGYQSWPSFSTLEKVSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAG 600

Query: 601 LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN 660
           LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN
Sbjct: 601 LHFKLPQSTDPLRTFKDTIYLTQVMQAQCVKTETEFYRRSRSEIVDQQGHTMGALYWQLN 660

Query: 661 DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV 720
           DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV
Sbjct: 661 DIWQAPSWASLEYGGKWKMLHYFAQNFFAPLLPVGFENENTFYIYGVSDLHSDYSMTLSV 720

Query: 721 RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE 780
           RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE
Sbjct: 721 RVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGNCTRESCVVSFYLSADHE 780

Query: 781 LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS 840
           LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS
Sbjct: 781 LLSPTNYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSIPGRFS 840

Query: 841 DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY 879
           DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY
Sbjct: 841 DNGFLMTEKTRTILFYPWEPTSKNELEQSFHVTSLTDIY 879


>gi|4504223 glucuronidase, beta [Homo sapiens]
          Length = 651

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 75/335 (22%), Positives = 128/335 (38%), Gaps = 57/335 (17%)

Query: 287 VETWWPHGHGNQTGYNMTVLFELDGGLNIEKSAKVYFRTVELIEEPIKGSPGLSFYFKIN 346
           V  WWP+    +  Y  ++  +L    ++   +  Y   V +    +  S      F IN
Sbjct: 285 VSLWWPYLMHERPAYLYSLEVQLTAQTSLGPVSDFYTLPVGIRTVAVTKSQ-----FLIN 339

Query: 347 GFPIFLKGSNWIPADSFQDRVTSELLRLLLQSVVDANMNTLRVWGGGIYEQ------DEF 400
           G P +  G N    +    R       LL++     + N LR  G   +        +E 
Sbjct: 340 GKPFYFHGVN--KHEDADIRGKGFDWPLLVK-----DFNLLRWLGANAFRTSHYPYAEEV 392

Query: 401 YELCDELGIMVWQDFMFACALYPTDQGFLDSVTAEVAYQI-----KRLKSHPSIIIWSGN 455
            ++CD  GI+V  +        P    F ++V+     Q+     +R K+HP++++WS  
Sbjct: 393 MQMCDRYGIVVIDECPGVGLALPQ---FFNNVSLHHHMQVMEEVVRRDKNHPAVVMWSVA 449

Query: 456 NENEEALMMNWYHISFTDRPIYIKDYVTLYVKNIRELVLAGDKSRPFITSSPTNGAETVA 515
           NE    L    Y++            V  + K++       D SRP    S +N A    
Sbjct: 450 NEPASHLESAGYYLKM----------VIAHTKSL-------DPSRPVTFVSNSNYAADKG 492

Query: 516 EAWVSQNPNSNYFGDVHFYDYI--------SDCWNW-KVFPKARFASEYGYQSWPSFSTL 566
             +V     ++Y+   H Y ++        +   NW K + K    SEYG ++   F   
Sbjct: 493 APYVDVICLNSYYSWYHDYGHLELIQLQLATQFENWYKKYQKPIIQSEYGAETIAGFHQD 552

Query: 567 EKVSSTEDWSFNSKFSLHRQHHEG-GNKQMLYQAG 600
             +  TE++    + SL  Q+H G   K+  Y  G
Sbjct: 553 PPLMFTEEY----QKSLLEQYHLGLDQKRRKYVVG 583


>gi|54859722 nucleoporin 160kDa [Homo sapiens]
          Length = 1436

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 18/50 (36%), Positives = 24/50 (48%), Gaps = 3/50 (6%)

Query: 786  NYHFLSSPKEAVGLCKAQITAIISQQGDIFVFDLETSAVAPFVWLDVGSI 835
            NY  L   +EAV L    + A++ +    F  +   SA AP VWL   SI
Sbjct: 1343 NYDLL---EEAVDLVSEYVDAVLGKGHQYFGIEFPLSATAPMVWLPYSSI 1389


>gi|7669530 neuregulin 2 isoform 3 [Homo sapiens]
          Length = 858

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 714 YSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGN 763
           Y  ++S  + +WS     C+   + + + GG  VC Y E +++L  +C N
Sbjct: 327 YVNSVSTTLSSWSGHARKCNETAKSYCVNGG--VCYYIEGINQLSCKCPN 374


>gi|4758832 neuregulin 2 isoform 1 [Homo sapiens]
          Length = 850

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 14/50 (28%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 714 YSMTLSVRVHTWSSLEPVCSRVTERFVMKGGEAVCLYEEPVSELLRRCGN 763
           Y  ++S  + +WS     C+   + + + GG  VC Y E +++L  +C N
Sbjct: 327 YVNSVSTTLSSWSGHARKCNETAKSYCVNGG--VCYYIEGINQLSCKCPN 374


>gi|28882043 TR4 orphan receptor associated protein TRA16 [Homo
           sapiens]
          Length = 139

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 30/107 (28%), Positives = 42/107 (39%), Gaps = 15/107 (14%)

Query: 512 ETVAEAWVSQNPNSNYFGDVHFYDYISD-CWNWKVFPKARFASEYGYQSWPS--FSTLEK 568
           ETV+      N N+  FG  H +D   + CWN          S+ G   W +  F  L +
Sbjct: 9   ETVSRVSSVLNRNTRQFGKKHLFDQDEETCWN----------SDQGPSQWVTLEFPQLIR 58

Query: 569 VSSTEDWSFNSKFSLHRQHHEGGNKQMLYQAGLHFKLPQSTDPLRTF 615
           VS  +   F   FS  R   EG          + F  P+  + L+TF
Sbjct: 59  VSQLQ-IQFQGGFSSRRGCLEGSQGTQALHKIVDF-YPEDNNSLQTF 103


>gi|120953264 folliculin interacting protein 1 isoform 2 [Homo
            sapiens]
          Length = 1138

 Score = 30.0 bits (66), Expect = 9.8
 Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 14/113 (12%)

Query: 179  NFVRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQE-------- 230
            NF R     +   + P F  QGI  D R     +  L++    P+ D+   E        
Sbjct: 967  NFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADM 1026

Query: 231  --WNLEIESTFDVVSSKPVGGQVIVA--IPKL--QTQQTYSIELQPGKRIVEL 277
              W +++ S+   V+   +G +V+V+  +  L   T Q Y   L P   ++ L
Sbjct: 1027 DKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHL 1079


>gi|120953291 folliculin interacting protein 1 isoform 1 [Homo
            sapiens]
          Length = 1166

 Score = 30.0 bits (66), Expect = 9.8
 Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 14/113 (12%)

Query: 179  NFVRKEQCSFSWDWGPSFPTQGIWKDVRIEAYNICHLNYFTFSPIYDKSAQE-------- 230
            NF R     +   + P F  QGI  D R     +  L++    P+ D+   E        
Sbjct: 995  NFGRSLLGGYCSSYVPDFVLQGIGSDERFRQCLMSDLSHAVQHPVLDEPIAEAVCIIADM 1054

Query: 231  --WNLEIESTFDVVSSKPVGGQVIVA--IPKL--QTQQTYSIELQPGKRIVEL 277
              W +++ S+   V+   +G +V+V+  +  L   T Q Y   L P   ++ L
Sbjct: 1055 DKWTVQVASSQRRVTDNKLGKEVLVSSLVSNLLHSTLQLYKHNLSPNFCVMHL 1107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,130,872
Number of Sequences: 37866
Number of extensions: 1521050
Number of successful extensions: 3043
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 3041
Number of HSP's gapped (non-prelim): 8
length of query: 879
length of database: 18,247,518
effective HSP length: 111
effective length of query: 768
effective length of database: 14,044,392
effective search space: 10786093056
effective search space used: 10786093056
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.