Search of human proteins with 8393018

Search of human proteins with 8393018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8393018 RWD domain containing 2B [Homo sapiens]
         (319 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8393018 RWD domain containing 2B [Homo sapiens]                    654   0.0  
gi|156523253 RWD domain containing 2A [Homo sapiens]                  181   6e-46
gi|153252154 RWD domain containing 3 isoform a [Homo sapiens]          44   2e-04
gi|189458889 RWD domain containing 3 isoform b [Homo sapiens]          40   0.003
gi|34878787 ring finger protein 25 [Homo sapiens]                      31   1.7  
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    30   2.2  
gi|20070228 nucleobindin 1 [Homo sapiens]                              29   4.9  
gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ...    29   6.3  
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             28   8.3  

>gi|8393018 RWD domain containing 2B [Homo sapiens]
          Length = 319

 Score =  654 bits (1686), Expect = 0.0
 Identities = 319/319 (100%), Positives = 319/319 (100%)

Query: 1   MKIELSMQPWNPGYSSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVND 60
           MKIELSMQPWNPGYSSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVND
Sbjct: 1   MKIELSMQPWNPGYSSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVND 60

Query: 61  QLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSDEKMAMFSLACILPFKYPAVLPEITV 120
           QLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSDEKMAMFSLACILPFKYPAVLPEITV
Sbjct: 61  QLAVAELKDCIEKKTMEGRSSKVYFTINMNLDVSDEKMAMFSLACILPFKYPAVLPEITV 120

Query: 121 RSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSSPTTGSTV 180
           RSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSSPTTGSTV
Sbjct: 121 RSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYVSRDTSSSPTTGSTV 180

Query: 181 QSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFW 240
           QSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFW
Sbjct: 181 QSVDLIFTRLWIYSHHIYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFW 240

Query: 241 SRLRKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKVFSVNGARGNHMDFGQLYQF 300
           SRLRKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKVFSVNGARGNHMDFGQLYQF
Sbjct: 241 SRLRKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKVFSVNGARGNHMDFGQLYQF 300

Query: 301 LNTKGCGDVFQMFFGVEGQ 319
           LNTKGCGDVFQMFFGVEGQ
Sbjct: 301 LNTKGCGDVFQMFFGVEGQ 319


>gi|156523253 RWD domain containing 2A [Homo sapiens]
          Length = 292

 Score =  181 bits (460), Expect = 6e-46
 Identities = 103/291 (35%), Positives = 159/291 (54%), Gaps = 14/291 (4%)

Query: 34  EQAEAQLAELDLLASMFPGENELIVNDQLAVAELKDCIEKKTMEGRSSKVYFTINMNLDV 93
           E  + QL E+++L SMFP + E+ + D  A+  +K  +E  T E    K+ F I + ++ 
Sbjct: 7   ESLQLQLLEMEMLFSMFPNQGEVKLEDVNALTNIKRYLEG-TREALPPKIEFVITLQIE- 64

Query: 94  SDEKMAMFSLACILPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILN 153
             E      L   +P  YP V  ++  RS  L R QQ  LN  LT+++     G++C+  
Sbjct: 65  --EPKVKIDLQVTMPHSYPYVALQLFGRSSELDRHQQLLLNKGLTSYIGTFDPGELCVCA 122

Query: 154 ATEWVREHASGY-VSRDTSSSPTTGSTVQSVDLIFTRLWIYSHHIYNKCKRKNILEWAKE 212
           A +W++++++ Y ++R     P+T +  + V   F R+WIYSHHIY +  RK IL+  K 
Sbjct: 123 AIQWLQDNSASYFLNRKLVYEPSTQA--KPVKNTFLRMWIYSHHIYQQDLRKKILDVGKR 180

Query: 213 LSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDGTNDETERQR 272
           L ++GF M GKPG++CVEG +  CEEFW  +R  NWK I  +H E +  +G  ++    R
Sbjct: 181 LDVTGFCMTGKPGIICVEGFKEHCEEFWHTIRYPNWKHISCKHAESVETEGNGEDL---R 237

Query: 273 KFSIFEEKVFSVNGARG----NHMDFGQLYQFLNTKGCGDVFQMFFGVEGQ 319
            F  FEE +   +G  G     HM+ GQ  +FL       VFQ+ FG+E +
Sbjct: 238 LFHSFEELLLEAHGDYGLRNDYHMNLGQFLEFLKKHKSEHVFQILFGIESK 288


>gi|153252154 RWD domain containing 3 isoform a [Homo sapiens]
          Length = 267

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/180 (21%), Positives = 82/180 (45%), Gaps = 17/180 (9%)

Query: 107 LPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYV 166
           LP  YP+ LP I++ S  L+R+Q   +  +L    +     +  +     W++++    +
Sbjct: 57  LPVNYPSCLPGISINSEQLTRAQCVTVKENLLEQAES-LLSEPMVHELVLWIQQNLRHIL 115

Query: 167 SRDTSSSPTTGSTVQSVDLIFTRLWI---YSHHIYNKCKRKNILE-WAKELSLSGFSM-P 221
           S+  + S +   T  +   +   LWI   +  H+  K K   I+E WA +L L+G  M  
Sbjct: 116 SQPETGSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFM 175

Query: 222 GKPGVVCVEGPQSACEEFWSRLRKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKV 281
           GK  ++ ++G ++  +E+           ++++    +  D +  + + +    +FE KV
Sbjct: 176 GKIILILLQGDRNNLKEY-----------LILQKTSKVDVDSSGKKCKEKMISVLFETKV 224


>gi|189458889 RWD domain containing 3 isoform b [Homo sapiens]
          Length = 195

 Score = 40.0 bits (92), Expect = 0.003
 Identities = 33/133 (24%), Positives = 64/133 (48%), Gaps = 6/133 (4%)

Query: 107 LPFKYPAVLPEITVRSVLLSRSQQTQLNTDLTAFLQKHCHGDVCILNATEWVREHASGYV 166
           LP  YP+ LP I++ S  L+R+Q   +  +L    +     +  +     W++++    +
Sbjct: 57  LPVNYPSCLPGISINSEQLTRAQCVTVKENLLEQAES-LLSEPMVHELVLWIQQNLRHIL 115

Query: 167 SRDTSSSPTTGSTVQSVDLIFTRLWI---YSHHIYNKCKRKNILE-WAKELSLSGFSM-P 221
           S+  + S +   T  +   +   LWI   +  H+  K K   I+E WA +L L+G  M  
Sbjct: 116 SQPETGSGSEKCTFSTSTTMDDGLWITLLHLDHMRAKTKYVKIVEKWASDLRLTGRLMFM 175

Query: 222 GKPGVVCVEGPQS 234
           GK  ++ ++G ++
Sbjct: 176 GKIILILLQGDRN 188


>gi|34878787 ring finger protein 25 [Homo sapiens]
          Length = 459

 Score = 30.8 bits (68), Expect = 1.7
 Identities = 19/81 (23%), Positives = 41/81 (50%), Gaps = 5/81 (6%)

Query: 47  ASMFPGENELIVNDQLAVAELKDCIEKKTMEGRSS----KVYFTIN-MNLDVSDEKMAMF 101
           AS   GE + ++  ++ V E     E + ++G       ++Y T++    +  D +   F
Sbjct: 5   ASAAAGEEDWVLPSEVEVLESIYLDELQVIKGNGRTSPWEIYITLHPATAEDQDSQYVCF 64

Query: 102 SLACILPFKYPAVLPEITVRS 122
           +L   +P +YP  +P+I++R+
Sbjct: 65  TLVLQVPAEYPHEVPQISIRN 85


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 30.4 bits (67), Expect = 2.2
 Identities = 20/63 (31%), Positives = 32/63 (50%), Gaps = 1/63 (1%)

Query: 15   SSEGATAQETYTCPKMIEMEQAEAQLAELDLLASMFPGENELIVNDQLAVAELKDCIEKK 74
            +  G T  E     K IE+E+A+ QLA L+   +    E   I+  QL + ++K  I++K
Sbjct: 1518 AENGKTIHELEKSRKQIELEKADIQLA-LEEAEAALEHEEAKILRIQLELTQVKSEIDRK 1576

Query: 75   TME 77
              E
Sbjct: 1577 IAE 1579


>gi|20070228 nucleobindin 1 [Homo sapiens]
          Length = 461

 Score = 29.3 bits (64), Expect = 4.9
 Identities = 22/61 (36%), Positives = 28/61 (45%), Gaps = 7/61 (11%)

Query: 227 VCVEGPQSACEEFWSRL-----RKLNWKRILIRHREDIPFDGTNDETERQRKFSIFEEKV 281
           V V G Q+  +E W  L      + N K   I H  DI  DG  DE E +  F+   EKV
Sbjct: 219 VNVPGSQAQLKEVWEELDGLDPNRFNPKTFFILH--DINSDGVLDEQELEALFTKELEKV 276

Query: 282 F 282
           +
Sbjct: 277 Y 277


>gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo
           sapiens]
          Length = 279

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 15/52 (28%), Positives = 22/52 (42%)

Query: 197 IYNKCKRKNILEWAKELSLSGFSMPGKPGVVCVEGPQSACEEFWSRLRKLNW 248
           IY    R  IL+W  E  ++   +P  PG   + G     +   S  R L+W
Sbjct: 8   IYKGTDRLGILQWVDEAQMAASPLPMYPGPTPLPGDDHETQHPPSSSRPLSW 59


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 28.5 bits (62), Expect = 8.3
 Identities = 17/63 (26%), Positives = 27/63 (42%), Gaps = 7/63 (11%)

Query: 196 HIYNKCKRKNILEWAKEL-SLSGFSMPGKPGVVCVEGPQSACEEFWSRLRK------LNW 248
           H+Y+ CK KNI E  +E+ +  G   P     +  E     C  +  R+R+        W
Sbjct: 143 HVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEW 202

Query: 249 KRI 251
           K +
Sbjct: 203 KHV 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,011,388
Number of Sequences: 37866
Number of extensions: 505256
Number of successful extensions: 1112
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1107
Number of HSP's gapped (non-prelim): 9
length of query: 319
length of database: 18,247,518
effective HSP length: 102
effective length of query: 217
effective length of database: 14,385,186
effective search space: 3121585362
effective search space used: 3121585362
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.