Search of human proteins with 83267874

Search of human proteins with 83267874

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3
[Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo...   774   0.0  
gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo ...   774   0.0  
gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo ...   501   e-142
gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo sa...   110   2e-24
gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo sa...   110   2e-24
gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo...    90   4e-18
gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo sapi...    42   0.001
gi|10092647 cardiolipin synthase 1 isoform 1 [Homo sapiens]            30   2.7  
gi|116517328 G-protein coupled receptor 115 [Homo sapiens]             29   6.0  
gi|21361304 regulator of G-protein signalling 14 [Homo sapiens]        29   7.9  

>gi|83267874 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score =  774 bits (1999), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60
           MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ
Sbjct: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60

Query: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120
           LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180
           LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180

Query: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240
           TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL
Sbjct: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240

Query: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300
           LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK
Sbjct: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300

Query: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360
           PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE
Sbjct: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360

Query: 361 IEKGSSYGNQEFKKKE 376
           IEKGSSYGNQEFKKKE
Sbjct: 361 IEKGSSYGNQEFKKKE 376


>gi|9910394 1-acylglycerol-3-phosphate O-acyltransferase 3 [Homo
           sapiens]
          Length = 376

 Score =  774 bits (1999), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60
           MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ
Sbjct: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60

Query: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120
           LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV
Sbjct: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120

Query: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180
           LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF
Sbjct: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180

Query: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240
           TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL
Sbjct: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240

Query: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300
           LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK
Sbjct: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300

Query: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360
           PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE
Sbjct: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360

Query: 361 IEKGSSYGNQEFKKKE 376
           IEKGSSYGNQEFKKKE
Sbjct: 361 IEKGSSYGNQEFKKKE 376


>gi|9910392 1-acylglycerol-3-phosphate O-acyltransferase 4 [Homo
           sapiens]
          Length = 378

 Score =  501 bits (1289), Expect = e-142
 Identities = 232/375 (61%), Positives = 291/375 (77%)

Query: 1   MGLLAFLKTQFVLHLLVGFVFVVSGLVINFVQLCTLALWPVSKQLYRRLNCRLAYSLWSQ 60
           M L   LK+QF+ HL+  +VF+ SGL+IN +QL TL LWP++KQL+R++NCRL+Y + SQ
Sbjct: 1   MDLAGLLKSQFLCHLVFCYVFIASGLIINTIQLFTLLLWPINKQLFRKINCRLSYCISSQ 60

Query: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120
           LVMLLEWWS TECT+FTD     ++GKE+A+++LNH FEIDFLCGW++ ERFG+LG SKV
Sbjct: 61  LVMLLEWWSGTECTIFTDPRAYLKYGKENAIVVLNHKFEIDFLCGWSLSERFGLLGGSKV 120

Query: 121 LAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLSDYPEYMWFLLYCEGTRF 180
           LAKKEL YVP+IGW WYF E+VFC RKWE+DR TV   L+ L DYPE  +FL++CEGTRF
Sbjct: 121 LAKKELAYVPIIGWMWYFTEMVFCSRKWEQDRKTVATSLQHLRDYPEKYFFLIHCEGTRF 180

Query: 181 TETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRGTVAAVYDVTLNFRGNKNPSL 240
           TE KH +SM+VA AKGLP LK+HLLPRTKGF   V+ LR  V+AVYD TLNFR N+NP+L
Sbjct: 181 TEKKHEISMQVARAKGLPRLKHHLLPRTKGFAITVRSLRNVVSAVYDCTLNFRNNENPTL 240

Query: 241 LGILYGKKYEADMCVRRFPLEDIPLDEKEAAQWLHKLYQEKDALQEIYNQKGMFPGEQFK 300
           LG+L GKKY AD+ VRR PLEDIP D+ E + WLHKLYQEKDA QE Y + G FP     
Sbjct: 241 LGVLNGKKYHADLYVRRIPLEDIPEDDDECSAWLHKLYQEKDAFQEEYYRTGTFPETPMV 300

Query: 301 PARRPWTLLNFLSWATILLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTE 360
           P RRPWTL+N+L WA+++L P F F++ +  SGS L + +F+     AS GVR +IGVTE
Sbjct: 301 PPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTE 360

Query: 361 IEKGSSYGNQEFKKK 375
           I+KGS+YGN + K+K
Sbjct: 361 IDKGSAYGNSDSKQK 375


>gi|42558246 lysocardiolipin acyltransferase 1 isoform 1 [Homo
           sapiens]
          Length = 414

 Score =  110 bits (275), Expect = 2e-24
 Identities = 94/322 (29%), Positives = 145/322 (45%), Gaps = 18/322 (5%)

Query: 36  LALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILN 95
           L L  V+   YR +N RL  +  +  V LLE     +  + T  A V     E +VII+N
Sbjct: 67  LPLMFVNPSWYRWINNRLVATWLTLPVALLETMFGVK-VIITGDAFVPG---ERSVIIMN 122

Query: 96  HNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTV 155
           H   +D++  W    R+  L   K+  K  L  VP  GW       +F  RKW++D+   
Sbjct: 123 HRTRMDWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHF 182

Query: 156 VEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAV 215
            + +    D  E +  L++ EGT  TE     S   A   GL   +Y L PRT GFT  V
Sbjct: 183 EDMIDYFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVV 242

Query: 216 KCLR--GTVAAVYDVTLNFRGNKNPSLLGILYGK-KYEADMCVRRFPLEDIPLDEKEAAQ 272
             LR    + AV+D+T+ +  N   S   +L G    E    V R+P++ +P  +++   
Sbjct: 243 DRLREGKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIHFHVHRYPIDTLPTSKEDLQL 302

Query: 273 WLHKLYQEK-DALQEIY--NQKGMFPGEQFKPARRP------WTLLNFLSWATILLSPLF 323
           W HK ++EK + L+  Y   +   F G+   P  +         LL+ L W   L SP  
Sbjct: 303 WCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWT--LFSPAM 360

Query: 324 SFVLGVFASGSPLLILTFLGFV 345
             ++ +++      I+T + FV
Sbjct: 361 CLLIYLYSLVKWYFIITIVIFV 382


>gi|50659059 lysocardiolipin acyltransferase 1 isoform 2 [Homo
           sapiens]
          Length = 376

 Score =  110 bits (275), Expect = 2e-24
 Identities = 94/322 (29%), Positives = 145/322 (45%), Gaps = 18/322 (5%)

Query: 36  LALWPVSKQLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILN 95
           L L  V+   YR +N RL  +  +  V LLE     +  + T  A V     E +VII+N
Sbjct: 29  LPLMFVNPSWYRWINNRLVATWLTLPVALLETMFGVK-VIITGDAFVPG---ERSVIIMN 84

Query: 96  HNFEIDFLCGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTV 155
           H   +D++  W    R+  L   K+  K  L  VP  GW       +F  RKW++D+   
Sbjct: 85  HRTRMDWMFLWNCLMRYSYLRLEKICLKASLKGVPGFGWAMQAAAYIFIHRKWKDDKSHF 144

Query: 156 VEGLRRLSDYPEYMWFLLYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAV 215
            + +    D  E +  L++ EGT  TE     S   A   GL   +Y L PRT GFT  V
Sbjct: 145 EDMIDYFCDIHEPLQLLIFPEGTDLTENSKSRSNAFAEKNGLQKYEYVLHPRTTGFTFVV 204

Query: 216 KCLR--GTVAAVYDVTLNFRGNKNPSLLGILYGK-KYEADMCVRRFPLEDIPLDEKEAAQ 272
             LR    + AV+D+T+ +  N   S   +L G    E    V R+P++ +P  +++   
Sbjct: 205 DRLREGKNLDAVHDITVAYPHNIPQSEKHLLQGDFPREIHFHVHRYPIDTLPTSKEDLQL 264

Query: 273 WLHKLYQEK-DALQEIY--NQKGMFPGEQFKPARRP------WTLLNFLSWATILLSPLF 323
           W HK ++EK + L+  Y   +   F G+   P  +         LL+ L W   L SP  
Sbjct: 265 WCHKRWEEKEERLRSFYQGEKNFYFTGQSVIPPCKSELRVLVVKLLSILYWT--LFSPAM 322

Query: 324 SFVLGVFASGSPLLILTFLGFV 345
             ++ +++      I+T + FV
Sbjct: 323 CLLIYLYSLVKWYFIITIVIFV 344


>gi|61743952 1-acylglycerol-3-phosphate O-acyltransferase 5 [Homo
           sapiens]
          Length = 364

 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 67/270 (24%), Positives = 130/270 (48%), Gaps = 20/270 (7%)

Query: 44  QLYRRLNCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFL 103
           + Y+ L+ RL     S ++   E ++  +  L+ D        KE+ + + NH   +D++
Sbjct: 45  RFYQALDDRLYCVYQSMVLFFFENYTGVQILLYGDLPK----NKENIIYLANHQSTVDWI 100

Query: 104 CGWTMCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIVFCKRKWEEDRDTVVEGLRRLS 163
               +  R   LG  + + K+ L ++PL G  +     ++ KR  + +   +   L+   
Sbjct: 101 VADILAIRQNALGHVRYVLKEGLKWLPLYGCYFAQHGGIYVKRSAKFNEKEMRNKLQSYV 160

Query: 164 DYPEYMWFLLYCEGTRFTETKHRV---SMEVAAAKGLPVLKYHLLPRTKGFTTAVKCLRG 220
           D    M+ +++ EGTR+   + +V   S   AA +GL VLK+ L PR K    A  C++ 
Sbjct: 161 DAGTPMYLVIFPEGTRYNPEQTKVLSASQAFAAQRGLAVLKHVLTPRIKATHVAFDCMKN 220

Query: 221 TVAAVYDVTLNFRG-------NKNPSLLGILYGKKYEADMCVRRFPLEDIPLDEKEAAQW 273
            + A+YDVT+ + G        ++P++   L  +  +  + + R   +D+P +++   +W
Sbjct: 221 YLDAIYDVTVVYEGKDDGGQRRESPTMTEFLCKECPKIHIHIDRIDKKDVPEEQEHMRRW 280

Query: 274 LHKLYQEKD-ALQEIY-----NQKGMFPGE 297
           LH+ ++ KD  L E Y      ++  FPG+
Sbjct: 281 LHERFEIKDKMLIEFYESPDPERRKRFPGK 310


>gi|7661996 lysophosphatidylglycerol acyltransferase 1 [Homo
           sapiens]
          Length = 370

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 68/302 (22%), Positives = 118/302 (39%), Gaps = 46/302 (15%)

Query: 61  LVMLLEWWSCTECTLFTDQATVERFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKV 120
           L M+  W      T+      ++   K+ AV+++NH    D +C   MC    +     V
Sbjct: 66  LGMVASWGWYAGYTVMEWGEDIKAVSKDEAVMLVNHQATGD-VCTLMMC----LQDKGLV 120

Query: 121 LAKKELLYVPLIGWTWYFLEIV----FCKRKWEEDRDTVVEGLRRLSDYP----EYMWFL 172
           +A+   L   +  +T + +  +    F  R+    RD  +  L++  +      +  W +
Sbjct: 121 VAQMMWLMDHIFKYTNFGIVSLVHGDFFIRQGRSYRDQQLLLLKKHLENNYRSRDRKWIV 180

Query: 173 LYCEGTRFTETKHRVSMEVAAAKGLPVLKYHLLPRTKGFTTAVKCL-----RGTVAA--- 224
           L+ EG  F   +   S   A    LP L    LPR+      +  L      G+ A    
Sbjct: 181 LFPEGG-FLRKRRETSQAFAKKNNLPFLTNVTLPRSGATKIILNALVAQQKNGSPAGGDA 239

Query: 225 ------------VYDVTLNFRGNK----NPSLLGILYGKKYEADMCVRRFPLEDIPLDEK 268
                       + D T+ +   +       +LG  Y K     +  R FP++D+PL+  
Sbjct: 240 KELDSKSKGLQWIIDTTIAYPKAEPIDIQTWILG--YRKPTVTHVHYRIFPIKDVPLETD 297

Query: 269 EAAQWLHKLYQEKDALQEIYNQKGMFPGEQ--FKPARRPWTLLNFLSWATILLSPLFSFV 326
           +   WL++ + EK+ L   + + G FP  +   +   R  TL N   W  I L   F+F+
Sbjct: 298 DLTTWLYQRFVEKEDLLSHFYETGAFPPSKGHKEAVSREMTLSNL--W--IFLIQSFAFL 353

Query: 327 LG 328
            G
Sbjct: 354 SG 355


>gi|10092647 cardiolipin synthase 1 isoform 1 [Homo sapiens]
          Length = 301

 Score = 30.4 bits (67), Expect = 2.7
 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 15/52 (28%)

Query: 295 PGEQFKPA------RRPWTLLNFLSWATILLSPL---------FSFVLGVFA 331
           PG Q+ PA        PWT+ N LS   I L+P+         F+  LGVFA
Sbjct: 90  PGGQWGPASTPSLYENPWTIPNMLSMTRIGLAPVLGYLIIEEDFNIALGVFA 141


>gi|116517328 G-protein coupled receptor 115 [Homo sapiens]
          Length = 695

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 18/62 (29%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 84  RFGKEHAVIILNHNFEIDFLCGWT-MCERFGVLGSSKVLAKKELLYVPLIGWTWYFLEIV 142
           R+ ++   ++L+   E+   C +T +   F +L SSK +  K L Y+  IG +   L +V
Sbjct: 358 RWDEKACQMMLDIRNEVKCRCNYTSVVMSFSILMSSKSMTDKVLDYITCIGLSVSILSLV 417

Query: 143 FC 144
            C
Sbjct: 418 LC 419


>gi|21361304 regulator of G-protein signalling 14 [Homo sapiens]
          Length = 566

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 13/84 (15%)

Query: 266 DEKEAAQWLHKLYQE---KDALQEIYNQKGMFPGEQFKPARRP----------WTLLNFL 312
           D ++ AQ    +YQE     AL  +   +  + GE+     RP          + L+ F 
Sbjct: 110 DTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFD 169

Query: 313 SWATILLSPLFSFVLGVFASGSPL 336
           S+A  + SPL+   L   A G PL
Sbjct: 170 SYARFVKSPLYRECLLAEAEGRPL 193


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,048,656
Number of Sequences: 37866
Number of extensions: 630813
Number of successful extensions: 1533
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1521
Number of HSP's gapped (non-prelim): 11
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.