Guide to the Human Genome
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Search of human proteins with 7657236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo
sapiens]
         (288 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens]     573   e-164
gi|221625487 inositol(myo)-1(or 4)-monophosphatase 1 isoform 2 [...   325   2e-89
gi|5031789 inositol(myo)-1(or 4)-monophosphatase 1 isoform 1 [Ho...   325   2e-89
gi|221625507 inositol(myo)-1(or 4)-monophosphatase 1 isoform 3 [...   192   2e-49
gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo sapiens]     57   2e-08
gi|157388900 inositol monophosphatase domain containing 1 [Homo ...    33   0.38 

>gi|7657236 inositol(myo)-1(or 4)-monophosphatase 2 [Homo sapiens]
          Length = 288

 Score =  573 bits (1476), Expect = e-164
 Identities = 288/288 (100%), Positives = 288/288 (100%)

Query: 1   MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 60
           MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL
Sbjct: 1   MKPSGEDQAALAAGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHL 60

Query: 61  VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 120
           VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI
Sbjct: 61  VEDLIISELRERFPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSI 120

Query: 121 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 180
           GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP
Sbjct: 121 GFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDP 180

Query: 181 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 240
           ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR
Sbjct: 181 ATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIR 240

Query: 241 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 288
           EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK
Sbjct: 241 EAGGIVIDTSGGPLDLMACRVVAASTREMAMLIAQALQTINYGRDDEK 288


>gi|221625487 inositol(myo)-1(or 4)-monophosphatase 1 isoform 2
           [Homo sapiens]
          Length = 336

 Score =  325 bits (834), Expect = 2e-89
 Identities = 147/275 (53%), Positives = 209/275 (76%)

Query: 13  AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72
           A PW+EC   AV LA +AG+++ +A+  E  V  K+S  DLVT TD  VE ++IS ++E+
Sbjct: 61  ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 120

Query: 73  FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132
           +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV
Sbjct: 121 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 180

Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192
           +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G  R P T+++ LSNME+
Sbjct: 181 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 240

Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252
           L     HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG
Sbjct: 241 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 300

Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287
           P DLM+ RV+AA+ R +A  IA+ +Q I   RDDE
Sbjct: 301 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 335


>gi|5031789 inositol(myo)-1(or 4)-monophosphatase 1 isoform 1 [Homo
           sapiens]
          Length = 277

 Score =  325 bits (834), Expect = 2e-89
 Identities = 147/275 (53%), Positives = 209/275 (76%)

Query: 13  AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72
           A PW+EC   AV LA +AG+++ +A+  E  V  K+S  DLVT TD  VE ++IS ++E+
Sbjct: 2   ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61

Query: 73  FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132
           +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV
Sbjct: 62  YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121

Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 192
           +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G  R P T+++ LSNME+
Sbjct: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181

Query: 193 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 252
           L     HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG
Sbjct: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241

Query: 253 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 287
           P DLM+ RV+AA+ R +A  IA+ +Q I   RDDE
Sbjct: 242 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276


>gi|221625507 inositol(myo)-1(or 4)-monophosphatase 1 isoform 3
           [Homo sapiens]
          Length = 198

 Score =  192 bits (489), Expect = 2e-49
 Identities = 87/148 (58%), Positives = 115/148 (77%)

Query: 13  AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72
           A PW+EC   AV LA +AG+++ +A+  E  V  K+S  DLVT TD  VE ++IS ++E+
Sbjct: 2   ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61

Query: 73  FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 132
           +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV
Sbjct: 62  YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121

Query: 133 IYHCTEERLYTGRRGRGAFCNGQRLRVS 160
           +Y C E ++YT R+G+GAFCNGQ+L+VS
Sbjct: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVS 149


>gi|116812595 3'(2'), 5'-bisphosphate nucleotidase 1 [Homo sapiens]
          Length = 308

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 74/271 (27%), Positives = 102/271 (37%), Gaps = 52/271 (19%)

Query: 22  AAVQLALRAGQIIRKALTE-EKRVSTKTSAADLVTETDHLVEDLIISELRERFPSHRFIA 80
           +A  +A +AG I+R+ + E +  +  KT A DL T+ D L +  I S L  +FP    I 
Sbjct: 14  SAYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIG 73

Query: 81  EEAAASGA-----------------KCVLTHSP-------TWIIDPIDGTCNFVHRF-PT 115
           EE   S                    C   +S         W+ DP+DGT  +       
Sbjct: 74  EEDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWV-DPLDGTKEYTEGLLDN 132

Query: 116 VAVSIGFAVRQELEFGVI---YHCTEE-------RLYTGRRGRGAFCNGQRLRVSGETDL 165
           V V IG A   +   GVI   Y+  E        R   G  G GAF  G +L+   E   
Sbjct: 133 VTVLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAF--GFQLK---EVPA 187

Query: 166 SKALVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQF 225
            K ++ T         T  +   N + +L     G ++I         L  G A AY   
Sbjct: 188 GKHIITTTRSHSNKLVTDCVAAMNPDAVLRVGGAGNKII--------QLIEGKASAYVFA 239

Query: 226 GLHC--WDLAAATVIIREAGGIVIDTSGGPL 254
              C  WD  A  VI+   GG + D  G  L
Sbjct: 240 SPGCKKWDTCAPEVILHAVGGKLTDIHGNVL 270


>gi|157388900 inositol monophosphatase domain containing 1 [Homo
           sapiens]
          Length = 359

 Score = 32.7 bits (73), Expect = 0.38
 Identities = 58/264 (21%), Positives = 97/264 (36%), Gaps = 38/264 (14%)

Query: 18  ECFQAAVQLALRAGQIIRKA-----LTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 72
           E    +V  A+R G  +R+      L E+ +  T+  A D +T  D L    +   L+  
Sbjct: 65  EMLAVSVLAAVRGGDEVRRVRESNVLHEKSKGKTREGAEDKMTSGDVLSNRKMFYLLKTA 124

Query: 73  FPSHRFIAEEAAASGAKCVL---------------------THSPTWIIDPIDGTCNF-- 109
           FPS +   EE   +  + V+                       S T  IDP+D T  +  
Sbjct: 125 FPSVQINTEEHVDAADQEVILWDHKIPEDILKEVTTPKEVPAESVTVWIDPLDATQEYTE 184

Query: 110 -VHRFPTVAVSIGFAVRQELEFGVIYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKA 168
            + ++ T  V +  AV  +   GVI+    E         G+     + R S      + 
Sbjct: 185 DLRKYVTTMVCV--AVNGKPMLGVIHKPFSEYTAWAMVDGGS---NVKARSSYNEKTPRI 239

Query: 169 LVLTEIGPKRDPATLKLFLSNMERLLHAKAHGVRVIGSSTLALCHLASGAADAYYQFG-L 227
           +V            L+ F  N   ++ A   G +V+  + L +   +   AD Y     +
Sbjct: 240 VVSRSHSGMVKQVALQTF-GNQTTIIPAGGAGYKVL--ALLDVPDKSQEKADLYIHVTYI 296

Query: 228 HCWDLAAATVIIREAGGIVIDTSG 251
             WD+ A   I++  GG +   SG
Sbjct: 297 KKWDICAGNAILKALGGHMTTLSG 320


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,777,298
Number of Sequences: 37866
Number of extensions: 383986
Number of successful extensions: 788
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 783
Number of HSP's gapped (non-prelim): 6
length of query: 288
length of database: 18,247,518
effective HSP length: 101
effective length of query: 187
effective length of database: 14,423,052
effective search space: 2697110724
effective search space used: 2697110724
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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