Guide to the Human Genome
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Search of human proteins with 73858570

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73858570 serpin peptidase inhibitor, clade G, member 1
precursor [Homo sapiens]
         (500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73858570 serpin peptidase inhibitor, clade G, member 1 precur...   978   0.0  
gi|73858568 serpin peptidase inhibitor, clade G, member 1 precur...   978   0.0  
gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens]                 166   5e-41
gi|39725934 serine (or cysteine) proteinase inhibitor, clade F (...   147   2e-35
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur...   142   7e-34
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o...   129   6e-30
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom...   127   2e-29
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo...   127   2e-29
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo...   127   2e-29
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo...   127   2e-29
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ...   125   9e-29
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a...   125   9e-29
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ...   124   2e-28
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (...   124   2e-28
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,...   123   3e-28
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member...   117   2e-26
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s...   117   3e-26
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (...   115   1e-25
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (...   115   1e-25
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (...   114   2e-25
gi|73858564 corticosteroid binding globulin precursor [Homo sapi...   114   2e-25
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (...   112   6e-25
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]          111   1e-24

>gi|73858570 serpin peptidase inhibitor, clade G, member 1 precursor
           [Homo sapiens]
          Length = 500

 Score =  978 bits (2527), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
           MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL
Sbjct: 1   MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60

Query: 61  EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
           EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG
Sbjct: 61  EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120

Query: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
           SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ
Sbjct: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180

Query: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
           VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS
Sbjct: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240

Query: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
           RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK
Sbjct: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300

Query: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
           TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP
Sbjct: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360

Query: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
           QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD
Sbjct: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420

Query: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
           FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV
Sbjct: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480

Query: 481 LWDQQHKFPVFMGRVYDPRA 500
           LWDQQHKFPVFMGRVYDPRA
Sbjct: 481 LWDQQHKFPVFMGRVYDPRA 500


>gi|73858568 serpin peptidase inhibitor, clade G, member 1 precursor
           [Homo sapiens]
          Length = 500

 Score =  978 bits (2527), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
           MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL
Sbjct: 1   MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60

Query: 61  EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
           EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG
Sbjct: 61  EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120

Query: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
           SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ
Sbjct: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180

Query: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
           VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS
Sbjct: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240

Query: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
           RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK
Sbjct: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300

Query: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
           TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP
Sbjct: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360

Query: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
           QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD
Sbjct: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420

Query: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
           FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV
Sbjct: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480

Query: 481 LWDQQHKFPVFMGRVYDPRA 500
           LWDQQHKFPVFMGRVYDPRA
Sbjct: 481 LWDQQHKFPVFMGRVYDPRA 500


>gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens]
          Length = 491

 Score =  166 bits (420), Expect = 5e-41
 Identities = 116/409 (28%), Positives = 204/409 (49%), Gaps = 13/409 (3%)

Query: 95  TTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLY 154
           T+ P  +   P T L   +  +P   +    P  +CS   +      L  A++ F+  L+
Sbjct: 36  TSGPNQEQVSPLTLLKLGNQ-EPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLF 94

Query: 155 HAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFT 214
            +  A      N+  SP S+A  L+ + LGA  +T   L+ +L         H   +   
Sbjct: 95  -SLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQ 153

Query: 215 TKGVTS---VSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTN 271
             G  +    ++++      I++ F+  S  L+ + P  L+   + +L  IN WV + T 
Sbjct: 154 DLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATE 213

Query: 272 NKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNSVIKVPMMNSKKY 330
            KI   L  LP DT L+LLNAI+    W+  FDP  T+ + FH  +   + V MM ++ Y
Sbjct: 214 GKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTY 273

Query: 331 PVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSK 390
           P+  F+ +  + +V      +N+S V+LVP + +    ++ Q L+   +  +   L   +
Sbjct: 274 PLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEW---NVSQVLANLSWDTLHPPLVWER 330

Query: 391 FQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELT 450
             PT + LP++ +    D+++ + +L   +     +L G++E   L VS +QHQ+ LEL+
Sbjct: 331 --PTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQ-SLVVSGVQHQSTLELS 387

Query: 451 ETGVEAAAASAISVAR-TLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
           E GVEAAAA++I+++R +L  F V +PFLF +++     P+F+G V +P
Sbjct: 388 EVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNP 436


>gi|39725934 serine (or cysteine) proteinase inhibitor, clade F
           (alpha-2 antiplasmin, pigment epithelium derived
           factor), member 1 [Homo sapiens]
          Length = 418

 Score =  147 bits (371), Expect = 2e-35
 Identities = 97/368 (26%), Positives = 181/368 (49%), Gaps = 15/368 (4%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
           L  A+ +F   LY   S+     TN+  SP S+A+ L+ + LGA + T++ +   L Y  
Sbjct: 54  LAAAVSNFGYDLYRVRSSTSPT-TNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL 112

Query: 201 ---KDFTCVHQALKGFTT---KGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNN 254
               D    ++ L    T   K + S S+I     L I+ +FV      Y + PRVL+ N
Sbjct: 113 ISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGN 172

Query: 255 SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFH 314
              +L+ IN WV      K++R    +P +  ++LL   +   +W T FD +KT +E F+
Sbjct: 173 PRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFY 232

Query: 315 F-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQA 373
             +   ++VPMM+  K  + + +D  L  K+ QL L+ ++S++  +P  +   L  +E++
Sbjct: 233 LDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEES 292

Query: 374 LSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTED 433
           L+      I  +L   K    +LT+P++K++   ++   +++++        +   +T  
Sbjct: 293 LTSEFIHDIDREL---KTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGK 349

Query: 434 PDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQHKFPVF 491
           P ++++ ++H+   E  E G     +  +  A     L + + QPF+FVL D      +F
Sbjct: 350 P-IKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLF 408

Query: 492 MGRVYDPR 499
           +G++ DPR
Sbjct: 409 IGKILDPR 416


>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
           [Homo sapiens]
          Length = 423

 Score =  142 bits (358), Expect = 7e-34
 Identities = 107/378 (28%), Positives = 182/378 (48%), Gaps = 25/378 (6%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPK 201
           L  A VDF+  LY     +K  + N+ FSP SI++ L  + LGA   T T +   L +  
Sbjct: 49  LASANVDFAFSLYKQL-VLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNL 107

Query: 202 DFTC---VHQALKGFTTKGVTSVSQI--------FHSPDLAIRDTFVNASRTLYSSSPRV 250
             T    +HQ+ +        S  ++        F    L++ D F   ++ LY S    
Sbjct: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167

Query: 251 LS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTR 309
               +S A  +LIN +V   T  KI+ L+  L S T +VL+N I+  AKW+  FDP+ T 
Sbjct: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227

Query: 310 MEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLE 368
              F+  K   + VPMM+     + +F D+ L   V +L+ + N S + ++P   + ++E
Sbjct: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPD--QDKME 285

Query: 369 DMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNL 427
           ++E  L P   K   + LE  +     L LP+  ++   ++  I+ +L   + F+   +L
Sbjct: 286 EVEAMLLPETLKRWRDSLEFREIGE--LYLPKFSISRDYNLNDILLQLGIEEAFTSKADL 343

Query: 428 CGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISV------ARTLLVFEVQQPFLFVL 481
            G+T   +L VS + H+ VL++ E G EA+AA+A+ +        T  +    +PFL ++
Sbjct: 344 SGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMII 403

Query: 482 WDQQHKFPVFMGRVYDPR 499
                +   FM +V +P+
Sbjct: 404 VPTDTQNIFFMSKVTNPK 421


>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 3 [Homo sapiens]
          Length = 390

 Score =  129 bits (324), Expect = 6e-30
 Identities = 112/395 (28%), Positives = 187/395 (47%), Gaps = 46/395 (11%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
           L +A   F   L+  F   K  E N+ +SP SI S L  VLLGA +NT   ++ +L +  
Sbjct: 4   LSEANTKFMFDLFQQFRKSK--ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61

Query: 201 ---------------KDFTCVHQALKGFTTKGVTS-------VSQIFHSPDLAIRDTFVN 238
                          +     HQ  K  T    ++        +++F          +++
Sbjct: 62  VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLD 121

Query: 239 ASRTLYSSSPRVL--SNNSDANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIY 294
           A +  Y +S   +  +N  + + + IN+WV   TN KI  L+   ++ S+T LVL+NAIY
Sbjct: 122 AIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIY 181

Query: 295 LSAKWKTTFDPKKTRMEPFH-FKNSVIKVPMMNSKKYPVAHFID-QTLKAKVGQLQLS-H 351
              +W+  F+ + T+ E F   KN+   + MM  ++Y   HF   + ++AKV ++     
Sbjct: 182 FKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMM--RQYTSFHFASLEDVQAKVLEIPYKGK 239

Query: 352 NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTL--LTLPRIKVTTSQDM 409
           +LS+++L+P  +   L+ +E+ L+    + +ME   +   + T   L LPR KV  S D+
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTA---EKLMEWTSLQNMRETRVDLHLPRFKVEESYDL 295

Query: 410 LSIMEKLEFFD-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAI-----S 463
              +  +   D F+ D +L G+T    L +S + H+  +E+TE G EAAAA+A+     S
Sbjct: 296 KDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSS 355

Query: 464 VARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
              T   F    PFLF +   +    +F GR   P
Sbjct: 356 PTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
           sapiens]
          Length = 418

 Score =  127 bits (319), Expect = 2e-29
 Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)

Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
           + H T   +   L +F+  LY    A +   TN+ FSP SIA+    + LG   +T   +
Sbjct: 42  QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100

Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
              L++        Q  +GF           +   +T+ + +F S  L + D F+   + 
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160

Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
           LY S    ++  +++   + IN +V K T  KI  L+  L  DT   L+N I+   KW+ 
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220

Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
            F+ K T  E FH    + +KVPMM     + + H   + L + V  ++   N + +  +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278

Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
           P   + +L+ +E  L+  +   I + LE    +   L LP++ +T + D+ S++ +L   
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333

Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
             FS   +L G+TE+  L++S   H+ VL + E G EAA A  +      +  EV+  +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393

Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
           F+F++ +Q  K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415


>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  125 bits (314), Expect = 9e-29
 Identities = 100/366 (27%), Positives = 179/366 (48%), Gaps = 32/366 (8%)

Query: 157 FSAMKKV----ETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-----------PK 201
           FS ++K+    + NM FSPF ++  +T ++LGA   T+T ++  L             P 
Sbjct: 84  FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPS 143

Query: 202 DFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS--PRVLSNNSDANL 259
            F  + + L      G+T  S  F   D  +++TF N S+  + +   P    N S A  
Sbjct: 144 LFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK- 202

Query: 260 ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNS 318
            L+N ++ K T  KI +L D +  +T+L+L++ I    KW T FDP  T ++ FH  K  
Sbjct: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262

Query: 319 VIKVPMM-NSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPS 377
            IKVPMM  + K+  A   D+  +  V +L    N ++++++ + +   L  +E  L+  
Sbjct: 263 TIKVPMMYGAGKF--ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTD 319

Query: 378 VFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTEDP 434
           + +  +  ++    +   +  P+ K+    +M  ++ ++     F    DL+    T   
Sbjct: 320 LVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-GR 375

Query: 435 DLQVSAMQHQTVLELTETGVEAAAA--SAISVARTLLVFEVQQPFLFVLWDQQHKFPVFM 492
           +LQVS +  +TV+E+ E G EA A   S I+      V +V +PF F+++++     +F+
Sbjct: 376 NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFL 435

Query: 493 GRVYDP 498
           GRV +P
Sbjct: 436 GRVVNP 441


>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 10 [Homo
           sapiens]
          Length = 444

 Score =  125 bits (314), Expect = 9e-29
 Identities = 100/366 (27%), Positives = 179/366 (48%), Gaps = 32/366 (8%)

Query: 157 FSAMKKV----ETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-----------PK 201
           FS ++K+    + NM FSPF ++  +T ++LGA   T+T ++  L             P 
Sbjct: 84  FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPS 143

Query: 202 DFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS--PRVLSNNSDANL 259
            F  + + L      G+T  S  F   D  +++TF N S+  + +   P    N S A  
Sbjct: 144 LFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK- 202

Query: 260 ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNS 318
            L+N ++ K T  KI +L D +  +T+L+L++ I    KW T FDP  T ++ FH  K  
Sbjct: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262

Query: 319 VIKVPMM-NSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPS 377
            IKVPMM  + K+  A   D+  +  V +L    N ++++++ + +   L  +E  L+  
Sbjct: 263 TIKVPMMYGAGKF--ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTD 319

Query: 378 VFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTEDP 434
           + +  +  ++    +   +  P+ K+    +M  ++ ++     F    DL+    T   
Sbjct: 320 LVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-GR 375

Query: 435 DLQVSAMQHQTVLELTETGVEAAAA--SAISVARTLLVFEVQQPFLFVLWDQQHKFPVFM 492
           +LQVS +  +TV+E+ E G EA A   S I+      V +V +PF F+++++     +F+
Sbjct: 376 NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFL 435

Query: 493 GRVYDP 498
           GRV +P
Sbjct: 436 GRVVNP 441


>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 5 [Homo
           sapiens]
          Length = 406

 Score =  124 bits (311), Expect = 2e-28
 Identities = 102/372 (27%), Positives = 189/372 (50%), Gaps = 33/372 (8%)

Query: 148 DFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVH 207
           DF+  LY A ++    ++ + FSP SI+  L  + LGAG +TK  +   L      +   
Sbjct: 47  DFTFDLYRALASAAPSQS-IFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEK 105

Query: 208 QALKGFTTK-----------GVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSD 256
           +  +GF               ++  + +F    + ++DTFV+A +TLY +     +    
Sbjct: 106 ELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDS 165

Query: 257 AN-LELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF 315
           A  ++ IN +VAK T  KI  LL +L S+  ++++N I+  AKW+T+F+ K T+ + F+ 
Sbjct: 166 AGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYV 225

Query: 316 -KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQAL 374
              +V++VPMM S++    + +D+ L  +V  +    N + + ++P   + +++ +E  L
Sbjct: 226 TSETVVRVPMM-SREDQYHYLLDRNLSCRVVGVPYQGNATALFILPS--EGKMQQVENGL 282

Query: 375 SPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGLTED 433
           S    K + + L+M K +   L LP+  +  S  +  ++  L   + F+   +L G++  
Sbjct: 283 SE---KTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNH 339

Query: 434 PDLQVSAMQHQTVLELTETGVEAAAAS-------AISVARTLLVFEVQQPFLFVLWDQQH 486
            ++QVS M H+ V+E+ E+G  AAAA+       +  +    LVF   +PFL  + D   
Sbjct: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVF--NRPFLMFIVDNN- 396

Query: 487 KFPVFMGRVYDP 498
              +F+G+V  P
Sbjct: 397 --ILFLGKVNRP 406


>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 4 [Homo sapiens]
          Length = 390

 Score =  124 bits (311), Expect = 2e-28
 Identities = 112/395 (28%), Positives = 185/395 (46%), Gaps = 46/395 (11%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
           L +A   F   L+  F   K  E N+ +SP SI S L  VLLGA +NT   +  +L +  
Sbjct: 4   LSEANTKFMFDLFQQFRKSK--ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61

Query: 201 ---------------KDFTCVHQALKGFTTKGVTS-------VSQIFHSPDLAIRDTFVN 238
                          +     HQ  K  T    ++        +++F          +++
Sbjct: 62  VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLD 121

Query: 239 ASRTLYSSSPRV--LSNNSDANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIY 294
           A +  Y +S      +N  + + + IN+WV   TN KI  L    ++ +DT LVL+NAIY
Sbjct: 122 AIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIY 181

Query: 295 LSAKWKTTFDPKKTRMEPFH-FKNSVIKVPMMNSKKYPVAHF-IDQTLKAKVGQLQLS-H 351
              +W+  F  + T+ E F   KN+   V MM  ++Y   +F + + ++AKV ++     
Sbjct: 182 FKGQWENKFKKENTKEEKFWPNKNTYKSVQMM--RQYNSFNFALLEDVQAKVLEIPYKGK 239

Query: 352 NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTL--LTLPRIKVTTSQDM 409
           +LS+++L+P  +   L+ +E+ L+    + +ME   +   + T   L LPR K+  S D+
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTA---EKLMEWTSLQNMRETCVDLHLPRFKMEESYDL 295

Query: 410 LSIMEKLEFFD-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVAR-- 466
              +  +   + F+ D +L G+T    L VS + H+  +E+TE GVEAAAA+A+ V    
Sbjct: 296 KDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELS 355

Query: 467 ---TLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
              T   F    PFLF +   +    +F GR   P
Sbjct: 356 SPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390


>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
           member 7 [Homo sapiens]
          Length = 415

 Score =  123 bits (309), Expect = 3e-28
 Identities = 104/397 (26%), Positives = 188/397 (47%), Gaps = 32/397 (8%)

Query: 125 GPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLG 184
           G VT C   + ++T   +     DF+  LY  F+ ++  + N+ FSP SI++ L  +  G
Sbjct: 25  GKVTACHSSQPNATLYKMSSINADFAFNLYRRFT-VETPDKNIFFSPVSISAALVMLSFG 83

Query: 185 AGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVS------------QIFHSPDLAI 232
           A  +T+T +   L +    T + +   GF    + S++             +F    L  
Sbjct: 84  ACCSTQTEIVETLGFNLTDTPMVEIQHGFQHL-ICSLNFPKKELELQIGNALFIGKHLKP 142

Query: 233 RDTFVNASRTLYSSS--PRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLL 290
              F+N  +TLY +       SN S A  E IN+ V   T  K+  L+  L  +T +VL+
Sbjct: 143 LAKFLNDVKTLYETEVFSTDFSNISAAKQE-INSHVEMQTKGKVVGLIQDLKPNTIMVLV 201

Query: 291 NAIYLSAKWKTTFDPKKTRMEPFHF--KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQ 348
           N I+  A+W   FDP KT         K + ++VPMM+  +    H +D  L   V Q+ 
Sbjct: 202 NYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQME-QYYHLVDMELNCTVLQMD 260

Query: 349 LSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQD 408
            S N   + ++P+  + ++E +E A+S    K     L+        L +P+  ++ + D
Sbjct: 261 YSKNALALFVLPK--EGQMESVEAAMSSKTLKKWNRLLQKGWVD---LFVPKFSISATYD 315

Query: 409 MLSIMEKLEF-FDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVA-- 465
           + + + K+     +S + +  GLTED  L++S   H+ VL + E G EAAA   + ++  
Sbjct: 316 LGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQ 375

Query: 466 --RTLL--VFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
              T L  + ++ + F+ ++ ++  +  +F+G+V +P
Sbjct: 376 PENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412


>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
           [Homo sapiens]
          Length = 405

 Score =  117 bits (293), Expect = 2e-26
 Identities = 96/376 (25%), Positives = 183/376 (48%), Gaps = 36/376 (9%)

Query: 148 DFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKD----- 202
           +F++ LY   S   K   N+ FSP  I  +L  V LGA    +  +   L   +      
Sbjct: 28  EFAVDLYQEVSLSHK--DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEE 85

Query: 203 -------FTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLS-NN 254
                  F+ + +  + FT       + ++      +++ +++ ++  + S+ +++   +
Sbjct: 86  FFVLKSFFSAISEKKQEFT---FNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD 142

Query: 255 SDANLELINTWVAKNTNNKISRLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEP 312
           + A  E+I+TWV + T+ KI  +   +     TRLVL+NAIY    WK  F  + T++  
Sbjct: 143 AKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLIN 202

Query: 313 FHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSH---NLSLVILVPQNLKHRL 367
           F  KN S +K+PMM +  +    +F + +L  +V  L+LS+     SL+I++P      +
Sbjct: 203 FTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQV--LELSYKGDEFSLIIILPAE-GMDI 259

Query: 368 EDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLN 426
           E++E+ ++    + I++ L   + +   ++LPR KV    D   ++  L   + FS   +
Sbjct: 260 EEVEKLITA---QQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCD 316

Query: 427 LCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLV----FEVQQPFLFVLW 482
           L G+T+  ++ VS +  +   E+ E G EAA ++ I +   + +    F    PFLF++ 
Sbjct: 317 LSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMK 376

Query: 483 DQQHKFPVFMGRVYDP 498
               +  +FMGRV +P
Sbjct: 377 HNPTESILFMGRVTNP 392


>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
           sapiens]
          Length = 376

 Score =  117 bits (292), Expect = 3e-26
 Identities = 105/355 (29%), Positives = 168/355 (47%), Gaps = 27/355 (7%)

Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
           N+  SP SI+S L  VLLGA  NT T +   LS   +   +H+A +   T+         
Sbjct: 27  NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEED-IHRAFQSLLTEVNKAGTQYL 85

Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLS--NNSDANLELINTWVAKNTNNKIS 275
           + + +++F         TF  +    Y +  + LS    ++ + + INTWV+K T  KI 
Sbjct: 86  LRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIE 145

Query: 276 RLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIK-VPMM-NSKKYP 331
            LL   S+ ++TRLVL+NAIY   KW   FD   TR  PF       + V MM     + 
Sbjct: 146 ELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFK 205

Query: 332 VAHFIDQTLKAKVGQLQLSH-NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSK 390
           +AH  +  ++A++ +L  +   LSL++L+P +    L  +E++L+     A   K +  K
Sbjct: 206 LAHVGE--VRAQLLELPYARKELSLLVLLPDD-GVELSTVEKSLTFEKLTA-WTKPDCMK 261

Query: 391 FQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD--LNLCGLTEDPDLQVSAMQHQTVLE 448
                + LP+ K+    DM S++  L   D       +L  ++ + DL +S   H++ +E
Sbjct: 262 STEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVE 321

Query: 449 LTETGVEAAAASAISVARTLLV-----FEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
           + E G EAAAAS+  V     +     F    PFLF +   +    +F GR   P
Sbjct: 322 VNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376


>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  115 bits (287), Expect = 1e-25
 Identities = 104/354 (29%), Positives = 163/354 (46%), Gaps = 27/354 (7%)

Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
           N+ FSP SI+S L  V +GA  +T   +   L   KD   +H+  +   ++         
Sbjct: 27  NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD-IHRGFQSLLSEVNRTGTQYL 85

Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDAN--LELINTWVAKNTNNKIS 275
           + + +++F          F    +  Y +    LS   D     + IN WVA+ T  KIS
Sbjct: 86  LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKIS 145

Query: 276 RLLDSLPSD--TRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVA 333
            +LD+   D  T+LVL+NAIY   KW   FD K TR   F        V MM  +     
Sbjct: 146 EVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKM 205

Query: 334 HFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKA--IMEKLEMSKF 391
            + D+     +    +   LS+VIL+P +    L  +E+AL+   FKA    EKL  SK 
Sbjct: 206 GYADEVHTQVLELPYVEEELSMVILLPDD-NTDLAVVEKALTYEKFKAWTNSEKLTKSKV 264

Query: 392 QPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD---LNLCGLTEDPDLQVSAMQHQTVLE 448
           Q   + LPR+K+  S D+   + +L   D ++D    +  G++ + ++ +S + H+  +E
Sbjct: 265 Q---VFLPRLKLEESYDLEPFLRRLGMID-AFDEAKADFSGMSTEKNVPLSKVAHKCFVE 320

Query: 449 LTETGVEAAAASAI----SVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
           + E G EAAAA+A+      +R    F    PFLF +   +    +F GR   P
Sbjct: 321 VNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 8 isoform a [Homo sapiens]
          Length = 374

 Score =  115 bits (287), Expect = 1e-25
 Identities = 104/354 (29%), Positives = 163/354 (46%), Gaps = 27/354 (7%)

Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
           N+ FSP SI+S L  V +GA  +T   +   L   KD   +H+  +   ++         
Sbjct: 27  NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD-IHRGFQSLLSEVNRTGTQYL 85

Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDAN--LELINTWVAKNTNNKIS 275
           + + +++F          F    +  Y +    LS   D     + IN WVA+ T  KIS
Sbjct: 86  LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKIS 145

Query: 276 RLLDSLPSD--TRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVA 333
            +LD+   D  T+LVL+NAIY   KW   FD K TR   F        V MM  +     
Sbjct: 146 EVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKM 205

Query: 334 HFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKA--IMEKLEMSKF 391
            + D+     +    +   LS+VIL+P +    L  +E+AL+   FKA    EKL  SK 
Sbjct: 206 GYADEVHTQVLELPYVEEELSMVILLPDD-NTDLAVVEKALTYEKFKAWTNSEKLTKSKV 264

Query: 392 QPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD---LNLCGLTEDPDLQVSAMQHQTVLE 448
           Q   + LPR+K+  S D+   + +L   D ++D    +  G++ + ++ +S + H+  +E
Sbjct: 265 Q---VFLPRLKLEESYDLEPFLRRLGMID-AFDEAKADFSGMSTEKNVPLSKVAHKCFVE 320

Query: 449 LTETGVEAAAASAI----SVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
           + E G EAAAA+A+      +R    F    PFLF +   +    +F GR   P
Sbjct: 321 VNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374


>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
           (alpha-1 antiproteinase, antitrypsin), member 4 [Homo
           sapiens]
          Length = 427

 Score =  114 bits (286), Expect = 2e-25
 Identities = 99/379 (26%), Positives = 180/379 (47%), Gaps = 27/379 (7%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPK 201
           +  A  DF+ + Y+   A +    N+ FSP SI++    + LGA  ++++ +   L +  
Sbjct: 51  IAPANADFAFRFYYLI-ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109

Query: 202 DFTCVHQALKGFTT---------KGVTSV--SQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
                    +GF            G+ +   S +F S +L     F+N +  +Y +  ++
Sbjct: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEA--KL 167

Query: 251 LSNN---SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKK 307
              N   +   ++LIN  V K T  KI  L+  L  D  +VL+N IY  A W+  F   +
Sbjct: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227

Query: 308 TRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHR 366
           T  + F+  +N+ ++VPMM   +    +  D+ L   V ++    + ++  ++P   K R
Sbjct: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 287

Query: 367 LEDMEQALSPSVFKAIMEKLEMSKFQPTL-LTLPRIKVTTSQDMLSIMEKLEFFD-FSYD 424
             ++E+ L+P +       L    F   L L LP+  ++ S  +  I+ +L F D FS  
Sbjct: 288 --EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345

Query: 425 LNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISV----ART-LLVFEVQQPFLF 479
            +L G+T+   L+ S   H+  L++ E G EAAAA++ ++    A+T   +    +PFL 
Sbjct: 346 ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLV 405

Query: 480 VLWDQQHKFPVFMGRVYDP 498
           V++    +  +F+G+V DP
Sbjct: 406 VIFSTSTQSVLFLGKVVDP 424


>gi|73858564 corticosteroid binding globulin precursor [Homo
           sapiens]
          Length = 405

 Score =  114 bits (285), Expect = 2e-25
 Identities = 97/373 (26%), Positives = 173/373 (46%), Gaps = 23/373 (6%)

Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-- 199
           L  A VDF+  LY    A+   + N+  SP SI+  L  + LG   +T+  L   L +  
Sbjct: 39  LASANVDFAFSLYKHLVALSP-KKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 97

Query: 200 -PKDFTCVHQAL--------KGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
             +  T +HQ          K  T+  +T  + +F    L + ++F    +  Y S    
Sbjct: 98  TERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157

Query: 251 LSNNSDANLEL-INTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTR 309
           ++    A     IN++V   T  KI  L   L S   LVL+N I+    W   FD   TR
Sbjct: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217

Query: 310 MEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLE 368
            E F+  + +V+KVPMM  +   +++  D  L  ++ Q+    N ++  ++P   K ++ 
Sbjct: 218 EENFYVDETTVVKVPMM-LQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPD--KGKMN 274

Query: 369 DMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNL 427
            +  ALS          L  S+     L +P++ ++   D+  ++E++   D F+   N 
Sbjct: 275 TVIAALSRDTINRWSAGLTSSQVD---LYIPKVTISGVYDLGDVLEEMGIADLFTNQANF 331

Query: 428 CGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQ 485
             +T+D  L+ S + H+ VL+L E GV+ A ++ +++  T   ++    QPF+ +++D  
Sbjct: 332 SRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHF 391

Query: 486 HKFPVFMGRVYDP 498
               +F+ RV +P
Sbjct: 392 TWSSLFLARVMNP 404


>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
           (ovalbumin), member 6 [Homo sapiens]
          Length = 376

 Score =  112 bits (281), Expect = 6e-25
 Identities = 105/379 (27%), Positives = 171/379 (45%), Gaps = 26/379 (6%)

Query: 141 VLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP 200
           VL +A   F+L L       K    N+ FSP S++  L  V +GA  NT   +  ILS+ 
Sbjct: 3   VLAEANGTFALNLLKTLG--KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60

Query: 201 KD--FTCVHQALKGFTTKG--------VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
           K      +HQ  +   T+         +   +++F         +F ++ +  Y +    
Sbjct: 61  KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEE 120

Query: 251 LSNNS--DANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIYLSAKWKTTFDPK 306
           L   S  + + + INTWVA+ T  KI+ LL   S+   TRLVL+NA+Y    W   FD +
Sbjct: 121 LDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKE 180

Query: 307 KTRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKH 365
            T    F   KN    V MM  +      +I +     +    +   L+++I++P     
Sbjct: 181 NTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTD 240

Query: 366 RLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDL 425
            L  +E+ L+   F     +L+M   +   ++LPR K+  S DM S++  L   D +++L
Sbjct: 241 -LRTVEKELTYEKF-VEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTD-AFEL 297

Query: 426 NLCGLT--EDPDLQVSAMQHQTVLELTETGVEAAAASA----ISVARTLLVFEVQQPFLF 479
                +     DL +S + H++ +E+ E G EAAAA+A    +  AR +  F    PFLF
Sbjct: 298 GKADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLF 357

Query: 480 VLWDQQHKFPVFMGRVYDP 498
            +   +    +F GR   P
Sbjct: 358 FIQHSKTNGILFCGRFSSP 376


>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
          Length = 402

 Score =  111 bits (278), Expect = 1e-24
 Identities = 102/393 (25%), Positives = 177/393 (45%), Gaps = 45/393 (11%)

Query: 136 HSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLES 195
           H   + +     DF ++++   +   K + N+ FSP+ +AS+L  + L  G  T+  +++
Sbjct: 25  HHPPSYVAHLASDFGVRVFQQVAQASK-DRNVVFSPYGVASVLAMLQLTTGGETQQQIQA 83

Query: 196 ILSYPKDFTCVHQALKG--------FTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS 247
            + +  D   +  AL+         +    +++   IF   DL +   F+     L+ S+
Sbjct: 84  AMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRST 143

Query: 248 PRVLSNNSDANLE-LINTWVAKNTNNKISRLLDSLPSD--TRLVLLNAIYLSAKWKTTFD 304
            + +  +       +IN WV  +T   IS LL     D  TRLVL+NA+Y + +WKT F 
Sbjct: 144 VKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFP 203

Query: 305 PKKTRMEPFHFKN-SVIKVPMM---NSKKY-----PVAHFIDQTLKAKVGQLQLSHN--- 352
              T    FH  + S + VPMM   N   Y     P  H+ D         L+L ++   
Sbjct: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYD--------ILELPYHGDT 255

Query: 353 LSLVILVPQNLKHRLEDMEQALSP---SVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDM 409
           LS+ I  P   +  L  +   LS    S +K  M +L      P LL LP+  + T  D+
Sbjct: 256 LSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRL------PRLLVLPKFSLETEVDL 309

Query: 410 LSIMEKLEFFDF--SYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVART 467
              +E L   D    +  +   L++   L V+    +  +E+ E+G  A++++A+ V+  
Sbjct: 310 RKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSAR 369

Query: 468 LLVFEV--QQPFLFVLWDQQHKFPVFMGRVYDP 498
           +   E+   +PFLFV+        +FMG+V +P
Sbjct: 370 MAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.128    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,650,914
Number of Sequences: 37866
Number of extensions: 773676
Number of successful extensions: 10645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 4769
Number of HSP's gapped (non-prelim): 3199
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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