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Search of human proteins with 73858568
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73858568 serpin peptidase inhibitor, clade G, member 1
precursor [Homo sapiens]
(500 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73858570 serpin peptidase inhibitor, clade G, member 1 precur... 978 0.0
gi|73858568 serpin peptidase inhibitor, clade G, member 1 precur... 978 0.0
gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens] 166 5e-41
gi|39725934 serine (or cysteine) proteinase inhibitor, clade F (... 147 2e-35
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 142 7e-34
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 129 6e-30
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 127 2e-29
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 127 2e-29
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 127 2e-29
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 127 2e-29
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 125 9e-29
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 125 9e-29
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 124 2e-28
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 124 2e-28
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 123 3e-28
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 117 2e-26
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 117 3e-26
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 115 1e-25
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 115 1e-25
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 114 2e-25
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 114 2e-25
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 112 6e-25
gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens] 111 1e-24
>gi|73858570 serpin peptidase inhibitor, clade G, member 1 precursor
[Homo sapiens]
Length = 500
Score = 978 bits (2527), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL
Sbjct: 1 MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
Query: 61 EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG
Sbjct: 61 EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
Query: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ
Sbjct: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
Query: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS
Sbjct: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
Query: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK
Sbjct: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
Query: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP
Sbjct: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
Query: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD
Sbjct: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
Query: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV
Sbjct: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
Query: 481 LWDQQHKFPVFMGRVYDPRA 500
LWDQQHKFPVFMGRVYDPRA
Sbjct: 481 LWDQQHKFPVFMGRVYDPRA 500
>gi|73858568 serpin peptidase inhibitor, clade G, member 1 precursor
[Homo sapiens]
Length = 500
Score = 978 bits (2527), Expect = 0.0
Identities = 500/500 (100%), Positives = 500/500 (100%)
Query: 1 MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL
Sbjct: 1 MASRLTLLTLLLLLLAGDRASSNPNATSSSSQDPESLQDRGEGKVATTVISKMLFVEPIL 60
Query: 61 EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG
Sbjct: 61 EVSSLPTTNSTTNSATKITANTTDEPTTQPTTEPTTQPTIQPTQPTTQLPTDSPTQPTTG 120
Query: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ
Sbjct: 121 SFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQ 180
Query: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS
Sbjct: 181 VLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNAS 240
Query: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK
Sbjct: 241 RTLYSSSPRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWK 300
Query: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP
Sbjct: 301 TTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVP 360
Query: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD
Sbjct: 361 QNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD 420
Query: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV
Sbjct: 421 FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQQPFLFV 480
Query: 481 LWDQQHKFPVFMGRVYDPRA 500
LWDQQHKFPVFMGRVYDPRA
Sbjct: 481 LWDQQHKFPVFMGRVYDPRA 500
>gi|115583663 alpha-2-plasmin inhibitor [Homo sapiens]
Length = 491
Score = 166 bits (420), Expect = 5e-41
Identities = 116/409 (28%), Positives = 204/409 (49%), Gaps = 13/409 (3%)
Query: 95 TTQPTIQPTQPTTQLPTDSPTQPTTGSFCPGPVTLCSDLESHSTEAVLGDALVDFSLKLY 154
T+ P + P T L + +P + P +CS + L A++ F+ L+
Sbjct: 36 TSGPNQEQVSPLTLLKLGNQ-EPGGQTALKSPPGVCSRDPTPEQTHRLARAMMAFTADLF 94
Query: 155 HAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFT 214
+ A N+ SP S+A L+ + LGA +T L+ +L H +
Sbjct: 95 -SLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQ 153
Query: 215 TKGVTS---VSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDANLELINTWVAKNTN 271
G + ++++ I++ F+ S L+ + P L+ + +L IN WV + T
Sbjct: 154 DLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATE 213
Query: 272 NKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNSVIKVPMMNSKKY 330
KI L LP DT L+LLNAI+ W+ FDP T+ + FH + + V MM ++ Y
Sbjct: 214 GKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTY 273
Query: 331 PVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSK 390
P+ F+ + + +V +N+S V+LVP + + ++ Q L+ + + L +
Sbjct: 274 PLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEW---NVSQVLANLSWDTLHPPLVWER 330
Query: 391 FQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTEDPDLQVSAMQHQTVLELT 450
PT + LP++ + D+++ + +L + +L G++E L VS +QHQ+ LEL+
Sbjct: 331 --PTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQ-SLVVSGVQHQSTLELS 387
Query: 451 ETGVEAAAASAISVAR-TLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
E GVEAAAA++I+++R +L F V +PFLF +++ P+F+G V +P
Sbjct: 388 EVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNP 436
>gi|39725934 serine (or cysteine) proteinase inhibitor, clade F
(alpha-2 antiplasmin, pigment epithelium derived
factor), member 1 [Homo sapiens]
Length = 418
Score = 147 bits (371), Expect = 2e-35
Identities = 97/368 (26%), Positives = 181/368 (49%), Gaps = 15/368 (4%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
L A+ +F LY S+ TN+ SP S+A+ L+ + LGA + T++ + L Y
Sbjct: 54 LAAAVSNFGYDLYRVRSSTSPT-TNVLLSPLSVATALSALSLGAEQRTESIIHRALYYDL 112
Query: 201 ---KDFTCVHQALKGFTT---KGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNN 254
D ++ L T K + S S+I L I+ +FV Y + PRVL+ N
Sbjct: 113 ISSPDIHGTYKELLDTVTAPQKNLKSASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLTGN 172
Query: 255 SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFH 314
+L+ IN WV K++R +P + ++LL + +W T FD +KT +E F+
Sbjct: 173 PRLDLQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFY 232
Query: 315 F-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQA 373
+ ++VPMM+ K + + +D L K+ QL L+ ++S++ +P + L +E++
Sbjct: 233 LDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEES 292
Query: 374 LSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDLNLCGLTED 433
L+ I +L K +LT+P++K++ ++ +++++ + +T
Sbjct: 293 LTSEFIHDIDREL---KTVQAVLTVPKLKLSYEGEVTKSLQEMKLQSLFDSPDFSKITGK 349
Query: 434 PDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQHKFPVF 491
P ++++ ++H+ E E G + + A L + + QPF+FVL D +F
Sbjct: 350 P-IKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHLNQPFIFVLRDTDTGALLF 408
Query: 492 MGRVYDPR 499
+G++ DPR
Sbjct: 409 IGKILDPR 416
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 142 bits (358), Expect = 7e-34
Identities = 107/378 (28%), Positives = 182/378 (48%), Gaps = 25/378 (6%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPK 201
L A VDF+ LY +K + N+ FSP SI++ L + LGA T T + L +
Sbjct: 49 LASANVDFAFSLYKQL-VLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNL 107
Query: 202 DFTC---VHQALKGFTTKGVTSVSQI--------FHSPDLAIRDTFVNASRTLYSSSPRV 250
T +HQ+ + S ++ F L++ D F ++ LY S
Sbjct: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
Query: 251 LS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTR 309
+S A +LIN +V T KI+ L+ L S T +VL+N I+ AKW+ FDP+ T
Sbjct: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
Query: 310 MEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLE 368
F+ K + VPMM+ + +F D+ L V +L+ + N S + ++P + ++E
Sbjct: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPD--QDKME 285
Query: 369 DMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNL 427
++E L P K + LE + L LP+ ++ ++ I+ +L + F+ +L
Sbjct: 286 EVEAMLLPETLKRWRDSLEFREIGE--LYLPKFSISRDYNLNDILLQLGIEEAFTSKADL 343
Query: 428 CGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISV------ARTLLVFEVQQPFLFVL 481
G+T +L VS + H+ VL++ E G EA+AA+A+ + T + +PFL ++
Sbjct: 344 SGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMII 403
Query: 482 WDQQHKFPVFMGRVYDPR 499
+ FM +V +P+
Sbjct: 404 VPTDTQNIFFMSKVTNPK 421
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 129 bits (324), Expect = 6e-30
Identities = 112/395 (28%), Positives = 187/395 (47%), Gaps = 46/395 (11%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
L +A F L+ F K E N+ +SP SI S L VLLGA +NT ++ +L +
Sbjct: 4 LSEANTKFMFDLFQQFRKSK--ENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQ 61
Query: 201 ---------------KDFTCVHQALKGFTTKGVTS-------VSQIFHSPDLAIRDTFVN 238
+ HQ K T ++ +++F +++
Sbjct: 62 VTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLD 121
Query: 239 ASRTLYSSSPRVL--SNNSDANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIY 294
A + Y +S + +N + + + IN+WV TN KI L+ ++ S+T LVL+NAIY
Sbjct: 122 AIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIY 181
Query: 295 LSAKWKTTFDPKKTRMEPFH-FKNSVIKVPMMNSKKYPVAHFID-QTLKAKVGQLQLS-H 351
+W+ F+ + T+ E F KN+ + MM ++Y HF + ++AKV ++
Sbjct: 182 FKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMM--RQYTSFHFASLEDVQAKVLEIPYKGK 239
Query: 352 NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTL--LTLPRIKVTTSQDM 409
+LS+++L+P + L+ +E+ L+ + +ME + + T L LPR KV S D+
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTA---EKLMEWTSLQNMRETRVDLHLPRFKVEESYDL 295
Query: 410 LSIMEKLEFFD-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAI-----S 463
+ + D F+ D +L G+T L +S + H+ +E+TE G EAAAA+A+ S
Sbjct: 296 KDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSS 355
Query: 464 VARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
T F PFLF + + +F GR P
Sbjct: 356 PTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 127 bits (319), Expect = 2e-29
Identities = 106/382 (27%), Positives = 184/382 (48%), Gaps = 25/382 (6%)
Query: 134 ESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNL 193
+ H T + L +F+ LY A + TN+ FSP SIA+ + LG +T +
Sbjct: 42 QDHPTFNKITPNLAEFAFSLYRQL-AHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEI 100
Query: 194 ESILSYPKDFTCVHQALKGF-----------TTKGVTSVSQIFHSPDLAIRDTFVNASRT 242
L++ Q +GF + +T+ + +F S L + D F+ +
Sbjct: 101 LEGLNFNLTEIPEAQIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKK 160
Query: 243 LYSSSPRVLS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKT 301
LY S ++ +++ + IN +V K T KI L+ L DT L+N I+ KW+
Sbjct: 161 LYHSEAFTVNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWER 220
Query: 302 TFDPKKTRMEPFHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSHNLSLVILV 359
F+ K T E FH + +KVPMM + + H + L + V ++ N + + +
Sbjct: 221 PFEVKDTEEEDFHVDQVTTVKVPMMKRLGMFNIQHC--KKLSSWVLLMKYLGNATAIFFL 278
Query: 360 PQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFF 419
P + +L+ +E L+ + I + LE + L LP++ +T + D+ S++ +L
Sbjct: 279 PD--EGKLQHLENELTHDI---ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGIT 333
Query: 420 D-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLVFEVQ--QP 476
FS +L G+TE+ L++S H+ VL + E G EAA A + + EV+ +P
Sbjct: 334 KVFSNGADLSGVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKP 393
Query: 477 FLFVLWDQQHKFPVFMGRVYDP 498
F+F++ +Q K P+FMG+V +P
Sbjct: 394 FVFLMIEQNTKSPLFMGKVVNP 415
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 125 bits (314), Expect = 9e-29
Identities = 100/366 (27%), Positives = 179/366 (48%), Gaps = 32/366 (8%)
Query: 157 FSAMKKV----ETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-----------PK 201
FS ++K+ + NM FSPF ++ +T ++LGA T+T ++ L P
Sbjct: 84 FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPS 143
Query: 202 DFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS--PRVLSNNSDANL 259
F + + L G+T S F D +++TF N S+ + + P N S A
Sbjct: 144 LFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK- 202
Query: 260 ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNS 318
L+N ++ K T KI +L D + +T+L+L++ I KW T FDP T ++ FH K
Sbjct: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262
Query: 319 VIKVPMM-NSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPS 377
IKVPMM + K+ A D+ + V +L N ++++++ + + L +E L+
Sbjct: 263 TIKVPMMYGAGKF--ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTD 319
Query: 378 VFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTEDP 434
+ + + ++ + + P+ K+ +M ++ ++ F DL+ T
Sbjct: 320 LVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-GR 375
Query: 435 DLQVSAMQHQTVLELTETGVEAAAA--SAISVARTLLVFEVQQPFLFVLWDQQHKFPVFM 492
+LQVS + +TV+E+ E G EA A S I+ V +V +PF F+++++ +F+
Sbjct: 376 NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFL 435
Query: 493 GRVYDP 498
GRV +P
Sbjct: 436 GRVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 125 bits (314), Expect = 9e-29
Identities = 100/366 (27%), Positives = 179/366 (48%), Gaps = 32/366 (8%)
Query: 157 FSAMKKV----ETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-----------PK 201
FS ++K+ + NM FSPF ++ +T ++LGA T+T ++ L P
Sbjct: 84 FSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPS 143
Query: 202 DFTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS--PRVLSNNSDANL 259
F + + L G+T S F D +++TF N S+ + + P N S A
Sbjct: 144 LFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAK- 202
Query: 260 ELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNS 318
L+N ++ K T KI +L D + +T+L+L++ I KW T FDP T ++ FH K
Sbjct: 203 RLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYK 262
Query: 319 VIKVPMM-NSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPS 377
IKVPMM + K+ A D+ + V +L N ++++++ + + L +E L+
Sbjct: 263 TIKVPMMYGAGKF--ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLA-LEDYLTTD 319
Query: 378 VFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTEDP 434
+ + + ++ + + P+ K+ +M ++ ++ F DL+ T
Sbjct: 320 LVETWLRNMKTRNME---VFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSAT-GR 375
Query: 435 DLQVSAMQHQTVLELTETGVEAAAA--SAISVARTLLVFEVQQPFLFVLWDQQHKFPVFM 492
+LQVS + +TV+E+ E G EA A S I+ V +V +PF F+++++ +F+
Sbjct: 376 NLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFL 435
Query: 493 GRVYDP 498
GRV +P
Sbjct: 436 GRVVNP 441
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 124 bits (311), Expect = 2e-28
Identities = 102/372 (27%), Positives = 189/372 (50%), Gaps = 33/372 (8%)
Query: 148 DFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVH 207
DF+ LY A ++ ++ + FSP SI+ L + LGAG +TK + L +
Sbjct: 47 DFTFDLYRALASAAPSQS-IFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEK 105
Query: 208 QALKGFTTK-----------GVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSD 256
+ +GF ++ + +F + ++DTFV+A +TLY + +
Sbjct: 106 ELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDS 165
Query: 257 AN-LELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF 315
A ++ IN +VAK T KI LL +L S+ ++++N I+ AKW+T+F+ K T+ + F+
Sbjct: 166 AGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYV 225
Query: 316 -KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQAL 374
+V++VPMM S++ + +D+ L +V + N + + ++P + +++ +E L
Sbjct: 226 TSETVVRVPMM-SREDQYHYLLDRNLSCRVVGVPYQGNATALFILPS--EGKMQQVENGL 282
Query: 375 SPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNLCGLTED 433
S K + + L+M K + L LP+ + S + ++ L + F+ +L G++
Sbjct: 283 SE---KTLRKWLKMFKKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNH 339
Query: 434 PDLQVSAMQHQTVLELTETGVEAAAAS-------AISVARTLLVFEVQQPFLFVLWDQQH 486
++QVS M H+ V+E+ E+G AAAA+ + + LVF +PFL + D
Sbjct: 340 SNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVF--NRPFLMFIVDNN- 396
Query: 487 KFPVFMGRVYDP 498
+F+G+V P
Sbjct: 397 --ILFLGKVNRP 406
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 124 bits (311), Expect = 2e-28
Identities = 112/395 (28%), Positives = 185/395 (46%), Gaps = 46/395 (11%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP- 200
L +A F L+ F K E N+ +SP SI S L VLLGA +NT + +L +
Sbjct: 4 LSEANTKFMFDLFQQFRKSK--ENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQ 61
Query: 201 ---------------KDFTCVHQALKGFTTKGVTS-------VSQIFHSPDLAIRDTFVN 238
+ HQ K T ++ +++F +++
Sbjct: 62 VTENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLD 121
Query: 239 ASRTLYSSSPRV--LSNNSDANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIY 294
A + Y +S +N + + + IN+WV TN KI L ++ +DT LVL+NAIY
Sbjct: 122 AIKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIY 181
Query: 295 LSAKWKTTFDPKKTRMEPFH-FKNSVIKVPMMNSKKYPVAHF-IDQTLKAKVGQLQLS-H 351
+W+ F + T+ E F KN+ V MM ++Y +F + + ++AKV ++
Sbjct: 182 FKGQWENKFKKENTKEEKFWPNKNTYKSVQMM--RQYNSFNFALLEDVQAKVLEIPYKGK 239
Query: 352 NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTL--LTLPRIKVTTSQDM 409
+LS+++L+P + L+ +E+ L+ + +ME + + T L LPR K+ S D+
Sbjct: 240 DLSMIVLLPNEIDG-LQKLEEKLTA---EKLMEWTSLQNMRETCVDLHLPRFKMEESYDL 295
Query: 410 LSIMEKLEFFD-FSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVAR-- 466
+ + + F+ D +L G+T L VS + H+ +E+TE GVEAAAA+A+ V
Sbjct: 296 KDTLRTMGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELS 355
Query: 467 ---TLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
T F PFLF + + +F GR P
Sbjct: 356 SPSTNEEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 123 bits (309), Expect = 3e-28
Identities = 104/397 (26%), Positives = 188/397 (47%), Gaps = 32/397 (8%)
Query: 125 GPVTLCSDLESHSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLG 184
G VT C + ++T + DF+ LY F+ ++ + N+ FSP SI++ L + G
Sbjct: 25 GKVTACHSSQPNATLYKMSSINADFAFNLYRRFT-VETPDKNIFFSPVSISAALVMLSFG 83
Query: 185 AGENTKTNLESILSYPKDFTCVHQALKGFTTKGVTSVS------------QIFHSPDLAI 232
A +T+T + L + T + + GF + S++ +F L
Sbjct: 84 ACCSTQTEIVETLGFNLTDTPMVEIQHGFQHL-ICSLNFPKKELELQIGNALFIGKHLKP 142
Query: 233 RDTFVNASRTLYSSS--PRVLSNNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLL 290
F+N +TLY + SN S A E IN+ V T K+ L+ L +T +VL+
Sbjct: 143 LAKFLNDVKTLYETEVFSTDFSNISAAKQE-INSHVEMQTKGKVVGLIQDLKPNTIMVLV 201
Query: 291 NAIYLSAKWKTTFDPKKTRMEPFHF--KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQ 348
N I+ A+W FDP KT K + ++VPMM+ + H +D L V Q+
Sbjct: 202 NYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQME-QYYHLVDMELNCTVLQMD 260
Query: 349 LSHNLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQD 408
S N + ++P+ + ++E +E A+S K L+ L +P+ ++ + D
Sbjct: 261 YSKNALALFVLPK--EGQMESVEAAMSSKTLKKWNRLLQKGWVD---LFVPKFSISATYD 315
Query: 409 MLSIMEKLEF-FDFSYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVA-- 465
+ + + K+ +S + + GLTED L++S H+ VL + E G EAAA + ++
Sbjct: 316 LGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQ 375
Query: 466 --RTLL--VFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
T L + ++ + F+ ++ ++ + +F+G+V +P
Sbjct: 376 PENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 117 bits (293), Expect = 2e-26
Identities = 96/376 (25%), Positives = 183/376 (48%), Gaps = 36/376 (9%)
Query: 148 DFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKD----- 202
+F++ LY S K N+ FSP I +L V LGA + + L +
Sbjct: 28 EFAVDLYQEVSLSHK--DNIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQETSAGEE 85
Query: 203 -------FTCVHQALKGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLS-NN 254
F+ + + + FT + ++ +++ +++ ++ + S+ +++ +
Sbjct: 86 FFVLKSFFSAISEKKQEFT---FNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVDFQD 142
Query: 255 SDANLELINTWVAKNTNNKISRLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEP 312
+ A E+I+TWV + T+ KI + + TRLVL+NAIY WK F + T++
Sbjct: 143 AKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQLIN 202
Query: 313 FHFKN-SVIKVPMMNS-KKYPVAHFIDQTLKAKVGQLQLSH---NLSLVILVPQNLKHRL 367
F KN S +K+PMM + + +F + +L +V L+LS+ SL+I++P +
Sbjct: 203 FTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQV--LELSYKGDEFSLIIILPAE-GMDI 259
Query: 368 EDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLN 426
E++E+ ++ + I++ L + + ++LPR KV D ++ L + FS +
Sbjct: 260 EEVEKLITA---QQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITEIFSGGCD 316
Query: 427 LCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTLLV----FEVQQPFLFVLW 482
L G+T+ ++ VS + + E+ E G EAA ++ I + + + F PFLF++
Sbjct: 317 LSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANHPFLFIMK 376
Query: 483 DQQHKFPVFMGRVYDP 498
+ +FMGRV +P
Sbjct: 377 HNPTESILFMGRVTNP 392
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 117 bits (292), Expect = 3e-26
Identities = 105/355 (29%), Positives = 168/355 (47%), Gaps = 27/355 (7%)
Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
N+ SP SI+S L VLLGA NT T + LS + +H+A + T+
Sbjct: 27 NVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNTEED-IHRAFQSLLTEVNKAGTQYL 85
Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLS--NNSDANLELINTWVAKNTNNKIS 275
+ + +++F TF + Y + + LS ++ + + INTWV+K T KI
Sbjct: 86 LRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSFIRAAEESRKHINTWVSKKTEGKIE 145
Query: 276 RLL--DSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIK-VPMM-NSKKYP 331
LL S+ ++TRLVL+NAIY KW FD TR PF + V MM +
Sbjct: 146 ELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTREMPFKINQEEQRPVQMMYQEATFK 205
Query: 332 VAHFIDQTLKAKVGQLQLSH-NLSLVILVPQNLKHRLEDMEQALSPSVFKAIMEKLEMSK 390
+AH + ++A++ +L + LSL++L+P + L +E++L+ A K + K
Sbjct: 206 LAHVGE--VRAQLLELPYARKELSLLVLLPDD-GVELSTVEKSLTFEKLTA-WTKPDCMK 261
Query: 391 FQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD--LNLCGLTEDPDLQVSAMQHQTVLE 448
+ LP+ K+ DM S++ L D +L ++ + DL +S H++ +E
Sbjct: 262 STEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLSAMSAERDLCLSKFVHKSFVE 321
Query: 449 LTETGVEAAAASAISVARTLLV-----FEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
+ E G EAAAAS+ V + F PFLF + + +F GR P
Sbjct: 322 VNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRHNRANSILFCGRFSSP 376
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 115 bits (287), Expect = 1e-25
Identities = 104/354 (29%), Positives = 163/354 (46%), Gaps = 27/354 (7%)
Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
N+ FSP SI+S L V +GA +T + L KD +H+ + ++
Sbjct: 27 NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD-IHRGFQSLLSEVNRTGTQYL 85
Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDAN--LELINTWVAKNTNNKIS 275
+ + +++F F + Y + LS D + IN WVA+ T KIS
Sbjct: 86 LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKIS 145
Query: 276 RLLDSLPSD--TRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVA 333
+LD+ D T+LVL+NAIY KW FD K TR F V MM +
Sbjct: 146 EVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKM 205
Query: 334 HFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKA--IMEKLEMSKF 391
+ D+ + + LS+VIL+P + L +E+AL+ FKA EKL SK
Sbjct: 206 GYADEVHTQVLELPYVEEELSMVILLPDD-NTDLAVVEKALTYEKFKAWTNSEKLTKSKV 264
Query: 392 QPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD---LNLCGLTEDPDLQVSAMQHQTVLE 448
Q + LPR+K+ S D+ + +L D ++D + G++ + ++ +S + H+ +E
Sbjct: 265 Q---VFLPRLKLEESYDLEPFLRRLGMID-AFDEAKADFSGMSTEKNVPLSKVAHKCFVE 320
Query: 449 LTETGVEAAAASAI----SVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
+ E G EAAAA+A+ +R F PFLF + + +F GR P
Sbjct: 321 VNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 115 bits (287), Expect = 1e-25
Identities = 104/354 (29%), Positives = 163/354 (46%), Gaps = 27/354 (7%)
Query: 166 NMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFTCVHQALKGFTTKG-------- 217
N+ FSP SI+S L V +GA +T + L KD +H+ + ++
Sbjct: 27 NVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYKDGD-IHRGFQSLLSEVNRTGTQYL 85
Query: 218 VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRVLSNNSDAN--LELINTWVAKNTNNKIS 275
+ + +++F F + Y + LS D + IN WVA+ T KIS
Sbjct: 86 LRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELSFAEDTEECRKHINDWVAEKTEGKIS 145
Query: 276 RLLDSLPSD--TRLVLLNAIYLSAKWKTTFDPKKTRMEPFHFKNSVIKVPMMNSKKYPVA 333
+LD+ D T+LVL+NAIY KW FD K TR F V MM +
Sbjct: 146 EVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYTRGMLFKTNEEKKTVQMMFKEAKFKM 205
Query: 334 HFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLEDMEQALSPSVFKA--IMEKLEMSKF 391
+ D+ + + LS+VIL+P + L +E+AL+ FKA EKL SK
Sbjct: 206 GYADEVHTQVLELPYVEEELSMVILLPDD-NTDLAVVEKALTYEKFKAWTNSEKLTKSKV 264
Query: 392 QPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYD---LNLCGLTEDPDLQVSAMQHQTVLE 448
Q + LPR+K+ S D+ + +L D ++D + G++ + ++ +S + H+ +E
Sbjct: 265 Q---VFLPRLKLEESYDLEPFLRRLGMID-AFDEAKADFSGMSTEKNVPLSKVAHKCFVE 320
Query: 449 LTETGVEAAAASAI----SVARTLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498
+ E G EAAAA+A+ +R F PFLF + + +F GR P
Sbjct: 321 VNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIRHHKTNCILFCGRFSSP 374
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 114 bits (286), Expect = 2e-25
Identities = 99/379 (26%), Positives = 180/379 (47%), Gaps = 27/379 (7%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPK 201
+ A DF+ + Y+ A + N+ FSP SI++ + LGA ++++ + L +
Sbjct: 51 IAPANADFAFRFYYLI-ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
Query: 202 DFTCVHQALKGFTT---------KGVTSV--SQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
+GF G+ + S +F S +L F+N + +Y + ++
Sbjct: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEA--KL 167
Query: 251 LSNN---SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKK 307
N + ++LIN V K T KI L+ L D +VL+N IY A W+ F +
Sbjct: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227
Query: 308 TRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHR 366
T + F+ +N+ ++VPMM + + D+ L V ++ + ++ ++P K R
Sbjct: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 287
Query: 367 LEDMEQALSPSVFKAIMEKLEMSKFQPTL-LTLPRIKVTTSQDMLSIMEKLEFFD-FSYD 424
++E+ L+P + L F L L LP+ ++ S + I+ +L F D FS
Sbjct: 288 --EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345
Query: 425 LNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISV----ART-LLVFEVQQPFLF 479
+L G+T+ L+ S H+ L++ E G EAAAA++ ++ A+T + +PFL
Sbjct: 346 ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLV 405
Query: 480 VLWDQQHKFPVFMGRVYDP 498
V++ + +F+G+V DP
Sbjct: 406 VIFSTSTQSVLFLGKVVDP 424
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 114 bits (285), Expect = 2e-25
Identities = 97/373 (26%), Positives = 173/373 (46%), Gaps = 23/373 (6%)
Query: 142 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSY-- 199
L A VDF+ LY A+ + N+ SP SI+ L + LG +T+ L L +
Sbjct: 39 LASANVDFAFSLYKHLVALSP-KKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 97
Query: 200 -PKDFTCVHQAL--------KGFTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
+ T +HQ K T+ +T + +F L + ++F + Y S
Sbjct: 98 TERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
Query: 251 LSNNSDANLEL-INTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTR 309
++ A IN++V T KI L L S LVL+N I+ W FD TR
Sbjct: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
Query: 310 MEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLE 368
E F+ + +V+KVPMM + +++ D L ++ Q+ N ++ ++P K ++
Sbjct: 218 EENFYVDETTVVKVPMM-LQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPD--KGKMN 274
Query: 369 DMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNL 427
+ ALS L S+ L +P++ ++ D+ ++E++ D F+ N
Sbjct: 275 TVIAALSRDTINRWSAGLTSSQVD---LYIPKVTISGVYDLGDVLEEMGIADLFTNQANF 331
Query: 428 CGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVARTL--LVFEVQQPFLFVLWDQQ 485
+T+D L+ S + H+ VL+L E GV+ A ++ +++ T ++ QPF+ +++D
Sbjct: 332 SRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHF 391
Query: 486 HKFPVFMGRVYDP 498
+F+ RV +P
Sbjct: 392 TWSSLFLARVMNP 404
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 112 bits (281), Expect = 6e-25
Identities = 105/379 (27%), Positives = 171/379 (45%), Gaps = 26/379 (6%)
Query: 141 VLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYP 200
VL +A F+L L K N+ FSP S++ L V +GA NT + ILS+
Sbjct: 3 VLAEANGTFALNLLKTLG--KDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFN 60
Query: 201 KD--FTCVHQALKGFTTKG--------VTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRV 250
K +HQ + T+ + +++F +F ++ + Y +
Sbjct: 61 KSGGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEE 120
Query: 251 LSNNS--DANLELINTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIYLSAKWKTTFDPK 306
L S + + + INTWVA+ T KI+ LL S+ TRLVL+NA+Y W FD +
Sbjct: 121 LDFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKE 180
Query: 307 KTRMEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKH 365
T F KN V MM + +I + + + L+++I++P
Sbjct: 181 NTEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTD 240
Query: 366 RLEDMEQALSPSVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKLEFFDFSYDL 425
L +E+ L+ F +L+M + ++LPR K+ S DM S++ L D +++L
Sbjct: 241 -LRTVEKELTYEKF-VEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTD-AFEL 297
Query: 426 NLCGLT--EDPDLQVSAMQHQTVLELTETGVEAAAASA----ISVARTLLVFEVQQPFLF 479
+ DL +S + H++ +E+ E G EAAAA+A + AR + F PFLF
Sbjct: 298 GKADFSGMSQTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLF 357
Query: 480 VLWDQQHKFPVFMGRVYDP 498
+ + +F GR P
Sbjct: 358 FIQHSKTNGILFCGRFSSP 376
>gi|10835159 plasminogen activator inhibitor-1 [Homo sapiens]
Length = 402
Score = 111 bits (278), Expect = 1e-24
Identities = 102/393 (25%), Positives = 177/393 (45%), Gaps = 45/393 (11%)
Query: 136 HSTEAVLGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLES 195
H + + DF ++++ + K + N+ FSP+ +AS+L + L G T+ +++
Sbjct: 25 HHPPSYVAHLASDFGVRVFQQVAQASK-DRNVVFSPYGVASVLAMLQLTTGGETQQQIQA 83
Query: 196 ILSYPKDFTCVHQALKG--------FTTKGVTSVSQIFHSPDLAIRDTFVNASRTLYSSS 247
+ + D + AL+ + +++ IF DL + F+ L+ S+
Sbjct: 84 AMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRST 143
Query: 248 PRVLSNNSDANLE-LINTWVAKNTNNKISRLLDSLPSD--TRLVLLNAIYLSAKWKTTFD 304
+ + + +IN WV +T IS LL D TRLVL+NA+Y + +WKT F
Sbjct: 144 VKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFP 203
Query: 305 PKKTRMEPFHFKN-SVIKVPMM---NSKKY-----PVAHFIDQTLKAKVGQLQLSHN--- 352
T FH + S + VPMM N Y P H+ D L+L ++
Sbjct: 204 DSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYD--------ILELPYHGDT 255
Query: 353 LSLVILVPQNLKHRLEDMEQALSP---SVFKAIMEKLEMSKFQPTLLTLPRIKVTTSQDM 409
LS+ I P + L + LS S +K M +L P LL LP+ + T D+
Sbjct: 256 LSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRL------PRLLVLPKFSLETEVDL 309
Query: 410 LSIMEKLEFFDF--SYDLNLCGLTEDPDLQVSAMQHQTVLELTETGVEAAAASAISVART 467
+E L D + + L++ L V+ + +E+ E+G A++++A+ V+
Sbjct: 310 RKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSAR 369
Query: 468 LLVFEV--QQPFLFVLWDQQHKFPVFMGRVYDP 498
+ E+ +PFLFV+ +FMG+V +P
Sbjct: 370 MAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.128 0.360
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,650,914
Number of Sequences: 37866
Number of extensions: 773676
Number of successful extensions: 10645
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 162
Number of HSP's successfully gapped in prelim test: 162
Number of HSP's that attempted gapping in prelim test: 4769
Number of HSP's gapped (non-prelim): 3199
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.