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Search of human proteins with 73858564
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
(405 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 805 0.0
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 335 3e-92
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 319 2e-87
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 317 2e-86
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 317 2e-86
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 317 2e-86
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 317 2e-86
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 302 3e-82
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 300 1e-81
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 296 2e-80
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 287 1e-77
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 261 8e-70
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 191 1e-48
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 187 1e-47
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 186 3e-47
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 186 4e-47
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 186 4e-47
gi|73858566 heparin cofactor II precursor [Homo sapiens] 182 4e-46
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 178 7e-45
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 178 9e-45
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 176 4e-44
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 173 2e-43
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 173 2e-43
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 805 bits (2079), Expect = 0.0
Identities = 405/405 (100%), Positives = 405/405 (100%)
Query: 1 MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPK 60
MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPK
Sbjct: 1 MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPK 60
Query: 61 KNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSD 120
KNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSD
Sbjct: 61 KNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSD 120
Query: 121 TSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQG 180
TSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQG
Sbjct: 121 TSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQG 180
Query: 181 KIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTI 240
KIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTI
Sbjct: 181 KIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTI 240
Query: 241 SYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLY 300
SYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLY
Sbjct: 241 SYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLY 300
Query: 301 IPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDT 360
IPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDT
Sbjct: 301 IPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDT 360
Query: 361 AGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV 405
AGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV
Sbjct: 361 AGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNPV 405
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 335 bits (860), Expect = 3e-92
Identities = 181/373 (48%), Positives = 240/373 (64%), Gaps = 6/373 (1%)
Query: 38 GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 97
GLASANVDFAFSLYK LV +P KN+ SP+SIS ALA LSLG T ++L+GL FNL
Sbjct: 48 GLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNL 107
Query: 98 TERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
TE SE EIHQ FQHL + +S L+++MGNA+F+ L LL+ F+ D K Y SE A
Sbjct: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
Query: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
+FQD A A + IN YVKN T+GKI DL LDS ++VLVNYIFFK W PFD T
Sbjct: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
Query: 218 EENFYVDETTVVKVPMM-LQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTV 276
+ FY+ + V VPMM L TI Y D EL C +V++ Y GN + FILPD+ KM V
Sbjct: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEV 287
Query: 277 IAALSRDTINRWSAGLTSSQV-DLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRIT 335
A L +T+ RW L ++ +LY+PK +IS Y+L D+L ++GI + FT++A+ S IT
Sbjct: 288 EAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGIT 347
Query: 336 QDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPI----ILRFNQPFIIMIFDHF 391
L S+VVHKAVL + EEG + + +T V + L S + I+RFN+PF+++I
Sbjct: 348 GARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTD 407
Query: 392 TWSSLFLARVMNP 404
T + F+++V NP
Sbjct: 408 TQNIFFMSKVTNP 420
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 319 bits (818), Expect = 2e-87
Identities = 169/374 (45%), Positives = 239/374 (63%), Gaps = 8/374 (2%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
+A AN DFAF Y + + +P KNIF SP+SIS A AMLSLG C H+R+Q+L+GLGFNLT
Sbjct: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
E SE+++H+GFQHL LE +G+ALFL +L+ L F D YE+++
Sbjct: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170
Query: 159 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 218
NF D + IN +VK +T+GKIVDL S L ++VLVNYI+FK W +PF + T
Sbjct: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230
Query: 219 ENFYVDETTVVKVPMMLQSSTIS-YLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVI 277
++FYVDE T V+VPMMLQ YLHD LPC +++M+Y G+ TVFFILP++GKM +
Sbjct: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290
Query: 278 AALSRDTINRWSAGLTS----SQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSR 333
L+ + + RW+ L +++L++PK +ISG Y L +L +G DLF+ A+ S
Sbjct: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350
Query: 334 ITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPI---ILRFNQPFIIMIFDH 390
IT+ +L++SK HKA L ++E G + A +T + S ILRFN+PF+++IF
Sbjct: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410
Query: 391 FTWSSLFLARVMNP 404
T S LFL +V++P
Sbjct: 411 STQSVLFLGKVVDP 424
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 317 bits (811), Expect = 2e-86
Identities = 161/360 (44%), Positives = 229/360 (63%)
Query: 45 DFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETE 104
+FAFSLY+ L S NIF SPVSI+ A AMLSLGT T ++L+GL FNLTE E +
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 105 IHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWA 164
IH+GFQ L + + D+ L++T GN LFL L+L++ F D+K Y SE +NF D
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 165 TASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVD 224
A +QIN YV+ TQGKIVDL LD + LVNYIFFKG W +PF++ T EE+F+VD
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 225 ETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDT 284
+ T VKVPMM + + H +L ++ M Y+GN T F LPD+GK+ + L+ D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 285 INRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSK 344
I ++ L++PK++I+G YDL VL ++GI +F+N A+ S +T++A LK SK
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 345 VVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
VHKAVL ++E+G + AG+ + S P ++FN+PF+ ++ + T S LF+ +V+NP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 302 bits (774), Expect = 3e-82
Identities = 167/410 (40%), Positives = 246/410 (60%), Gaps = 10/410 (2%)
Query: 1 MPLLLYTCLLWLPTSGLWTVQAMDPNAAYVNMSNHHRGLA---SANVDFAFSLYKHLVAL 57
M L L CL+ L G ++ P + + H G S+ DF F LY+ L +
Sbjct: 1 MQLFLLLCLVLLSPQGA-SLHRHHPREMKKRVEDLHVGATVAPSSRRDFTFDLYRALASA 59
Query: 58 SPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFA 117
+P ++IF SPVSISM+LAMLSLG T+ Q+L+GLG NL + SE E+H+GFQ L Q
Sbjct: 60 APSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELN 119
Query: 118 KSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNK 177
+ ++++GNALF D ++L ++F + +K Y ++ NF+D A A +QIN YV +
Sbjct: 120 QPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQ 179
Query: 178 TQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREENFYVDETTVVKVPMMLQS 237
T+GKIVDL LDS A++++VNYIFFK W F+ T+E++FYV TVV+VPMM +
Sbjct: 180 TKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSRE 239
Query: 238 STISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQV 297
YL D L C++V + Y GN T FILP +GKM V LS T+ +W Q+
Sbjct: 240 DQYHYLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQL 299
Query: 298 DLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEG 357
+LY+PK +I G Y L VL +GI+++FT+ A+ S I+ + ++ S++VHKAV++++E G
Sbjct: 300 ELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESG 359
Query: 358 VDTAGSTGVTLNLTSKPI---ILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
A +TG S + L FN+PF++ I D+ + LFL +V P
Sbjct: 360 TRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN---NILFLGKVNRP 406
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 300 bits (769), Expect = 1e-81
Identities = 163/369 (44%), Positives = 226/369 (61%), Gaps = 5/369 (1%)
Query: 41 SANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTER 100
S N DFAF LY+ LV +P +NIF SPVS+S +LAMLSLG T+ Q+LQGLGFNLT
Sbjct: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHT 123
Query: 101 SETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNF 160
E+ IHQGFQHL L + MG+ALF+ L+L +F ++K YE+EV + +F
Sbjct: 124 PESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDF 183
Query: 161 QDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTREE- 219
+ + A +INS+VK KTQGK+VD+ GLD +VLVN+IFFK W +PF TR+
Sbjct: 184 SNPSIAQARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNF 243
Query: 220 NFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIAA 279
F V E V VPMM Q ++ D EL C ++QM+Y G+ FF+LP KGKM + A
Sbjct: 244 PFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQA 303
Query: 280 LSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDAQ 339
LS T+ +WS L ++++IP+ +IS Y+L +L +MGI ++F A+FS I +
Sbjct: 304 LSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDS 363
Query: 340 LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFIIMIFDHFTWSS 395
L+ SK HKAVL ++EEG + +T + SK + FN+ F++MI + T
Sbjct: 364 LQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGI 423
Query: 396 LFLARVMNP 404
LFL +V NP
Sbjct: 424 LFLGKVENP 432
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 296 bits (758), Expect = 2e-80
Identities = 166/398 (41%), Positives = 234/398 (58%), Gaps = 14/398 (3%)
Query: 13 PTSGLWTVQAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISM 72
P + + PNA MS S N DFAF+LY+ +P KNIF SPVSIS
Sbjct: 23 PEGKVTACHSSQPNATLYKMS-------SINADFAFNLYRRFTVETPDKNIFFSPVSISA 75
Query: 73 ALAMLSLGTCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALF 132
AL MLS G C T+ ++++ LGFNLT+ EI GFQHL LE+ +GNALF
Sbjct: 76 ALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLICSLNFPKKELELQIGNALF 135
Query: 133 LDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSP 192
+ L+ L F D+K YE+EV + +F + + A ++INS+V+ +T+GK+V L L
Sbjct: 136 IGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPN 195
Query: 193 AILVLVNYIFFKGTWTQPFDLASTREEN-FYVDETTVVKVPMMLQSSTISYLHDAELPCQ 251
I+VLVNYI FK W PFD + T + + F +D+TT V+VPMM Q +L D EL C
Sbjct: 196 TIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCT 255
Query: 252 LVQMNYVGNGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYD 311
++QM+Y N F+LP +G+M +V AA+S T+ +W+ L VDL++PK +IS YD
Sbjct: 256 VLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYD 315
Query: 312 LGDVLEEMGIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTL--- 368
LG L +MGI ++ A+FS +T+D LK S HKAVL + E+G + A V L
Sbjct: 316 LGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQ 375
Query: 369 --NLTSKPIILRFNQPFIIMIFDHFTWSSLFLARVMNP 404
N PII + ++ F+++I + T S LFL +V+NP
Sbjct: 376 PENTFLHPII-QIDRSFMLLILERSTRSILFLGKVVNP 412
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 287 bits (734), Expect = 1e-77
Identities = 159/391 (40%), Positives = 232/391 (59%), Gaps = 15/391 (3%)
Query: 21 QAMDPNAAYVNMSNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLG 80
Q +P AY HR + +FA LYK L A +P NIF SPVSIS LA+LSLG
Sbjct: 39 QLSEPAPAY------HR-ITPTITNFALRLYKELAADAPG-NIFFSPVSISTTLALLSLG 90
Query: 81 TCGHTRAQLLQGLGFNLTERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELL 140
+T A +L+GLGFNLTE E +IHQGF+ L A LE+ +GN+LFLD L+
Sbjct: 91 AQANTSALILEGLGFNLTETPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPR 150
Query: 141 ESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNY 200
+ + IK Y + + NF D T RQIN Y++ +T G++VD +VL NY
Sbjct: 151 QHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANY 210
Query: 201 IFFKGTWTQPFDLAST-REENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVG 259
IFFK W PF T ++E+F+VDE T ++VPMM Q +L+D +L C ++Q+ Y G
Sbjct: 211 IFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRG 270
Query: 260 NGTVFFILPDKGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEM 319
N +LPD GKM V AAL T+ +W L S +DL++P+ +ISG Y+L D+L ++
Sbjct: 271 NALALLVLPDPGKMKQVEAALQPQTLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQI 330
Query: 320 GIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGV-----TLNLTSKP 374
G+ ++ +A+FS +T SKV HKA++ ++E+G + ++G+ +LN S P
Sbjct: 331 GLTNILNLEADFSGVTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP 390
Query: 375 IILRFNQPFIIMIFDHFTWSSLFLARVMNPV 405
FN+PF++++++ T S LFL +V+NPV
Sbjct: 391 -HAHFNRPFLLLLWEVTTQSLLFLGKVVNPV 420
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 261 bits (667), Expect = 8e-70
Identities = 127/367 (34%), Positives = 215/367 (58%), Gaps = 2/367 (0%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
LA N+D F L K L +P +NIF+SP+SIS A +ML LG T ++ QG FN
Sbjct: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFR 105
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
+ E ++H+GF ++ + L++++GN LF+D L+ F D K++Y +E +
Sbjct: 106 KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILT 165
Query: 159 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 218
NFQ+ A +QIN ++ KT GKI +L +D +++L NYIFF+ W FD T+E
Sbjct: 166 NFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE 225
Query: 219 ENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIA 278
E+F++++ + VKVPMM +S +D +L C ++++ Y N T FILPD+GK+ +
Sbjct: 226 EDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEK 285
Query: 279 ALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDA 338
L DT +RW L+ VD+ +P++ ++G +DL L +G++ +F + ++I
Sbjct: 286 GLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHR 345
Query: 339 QLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFL 398
LK + VHKA L+++E G + A TG P++++ ++P++++I+ S LFL
Sbjct: 346 SLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFL 405
Query: 399 ARVMNPV 405
+++NP+
Sbjct: 406 GKIVNPI 412
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 191 bits (484), Expect = 1e-48
Identities = 130/380 (34%), Positives = 206/380 (54%), Gaps = 21/380 (5%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
L++A+ FA L K L +P N+F SPVSIS ALAM+ LG G+T Q+ Q L N
Sbjct: 4 LSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN-- 61
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
+E +IH+ FQ L K+ T + N LF + + + L +F +Y +E+ +
Sbjct: 62 --TEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKEL 119
Query: 159 NFQDWATASRQ-INSYVKNKTQGKIVDLFSG--LDSPAILVLVNYIFFKGTWTQPFDLAS 215
+F A SR+ IN++V KT+GKI +L G +D+ LVLVN I+FKG W +PFD
Sbjct: 120 SFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETY 179
Query: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDKG-KM 273
TRE F +++ V MM Q +T H E+ QL+++ Y ++ +LPD G ++
Sbjct: 180 TREMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVEL 239
Query: 274 NTVIAALSRDTINRWSAG--LTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLF-TNQAN 330
+TV +L+ + + W+ + S++V++ +PK + YD+ VL +GI D F +A+
Sbjct: 240 STVEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKAD 299
Query: 331 FSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTG----VTLNLTSKPIILRF--NQPFI 384
S ++ + L SK VHK+ +++NEEG + A ++ + S P RF + PF+
Sbjct: 300 LSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGP---RFCADHPFL 356
Query: 385 IMIFDHFTWSSLFLARVMNP 404
I + S LF R +P
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 187 bits (475), Expect = 1e-47
Identities = 129/376 (34%), Positives = 201/376 (53%), Gaps = 13/376 (3%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
LA AN FA +L K L KN+F SP+S+S ALAM+ +G G+T AQ+ Q L FN +
Sbjct: 4 LAEANGTFALNLLKTL-GKDNSKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKS 62
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
+IHQGFQ L K+ T + M N LF + S + L SF + +Y++E+ +
Sbjct: 63 GGGG-DIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEEL 121
Query: 159 NFQDWATASRQ-INSYVKNKTQGKIVDLFS--GLDSPAILVLVNYIFFKGTWTQPFDLAS 215
+F SR+ IN++V KT+GKI +L S +D LVLVN ++F+G W + FD +
Sbjct: 122 DFISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKEN 181
Query: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDK-GKM 273
T E F V + V MM + ST + E+ Q++ + YVG + +LPD+ +
Sbjct: 182 TEERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDL 241
Query: 274 NTVIAALSRDTINRWSA--GLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLF-TNQAN 330
TV L+ + W+ + +V++ +P+ + YD+ VL +G+ D F +A+
Sbjct: 242 RTVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKAD 301
Query: 331 FSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQPFIIMIF 388
FS ++Q L SKVVHK+ +++NEEG + A +T + + + RF + PF+ I
Sbjct: 302 FSGMSQ-TDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQ 360
Query: 389 DHFTWSSLFLARVMNP 404
T LF R +P
Sbjct: 361 HSKTNGILFCGRFSSP 376
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 186 bits (472), Expect = 3e-47
Identities = 105/259 (40%), Positives = 150/259 (57%), Gaps = 5/259 (1%)
Query: 151 YESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQP 210
Y VL Q+ + +INS+VK KTQGK+VD+ GLD +VLVN+IFFK W +P
Sbjct: 74 YRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKP 133
Query: 211 FDLASTREE-NFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPD 269
F TR+ F V E V VPMM Q ++ D EL C ++QM+Y G+ FF+LP
Sbjct: 134 FHPEYTRKNFPFLVGEQVTVHVPMMHQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPS 193
Query: 270 KGKMNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQA 329
KGKM + ALS T+ +WS L ++++IP+ +IS Y+L +L +MGI ++F A
Sbjct: 194 KGKMRQLEQALSARTLRKWSHSLQKRWIEVFIPRFSISASYNLETILPKMGIQNVFDKNA 253
Query: 330 NFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFII 385
+FS I + L+ SK HKAVL ++EEG + +T + SK + FN+ F++
Sbjct: 254 DFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLM 313
Query: 386 MIFDHFTWSSLFLARVMNP 404
MI + T LFL +V NP
Sbjct: 314 MITNKATDGILFLGKVENP 332
Score = 38.5 bits (88), Expect = 0.011
Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 4/53 (7%)
Query: 41 SANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGL 93
S N DFAF LY+ LV +P +NIF SP I+ + + G ++QGL
Sbjct: 64 SLNTDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKV----VDIIQGL 112
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 186 bits (471), Expect = 4e-47
Identities = 104/369 (28%), Positives = 199/369 (53%), Gaps = 5/369 (1%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
LA +F FSL + +++ N+ SP +S+A+ L LG G T Q+ +GL
Sbjct: 75 LAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
Query: 99 ERSETEIHQG-FQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
+ ++ + F+ L + +++ L +T G+ F+ ++ E+F K Y+++E +
Sbjct: 134 KPTKPGLLPSLFKGLRETLSRN-LELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
Query: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
MNF++ + A R +N Y+ +T+GKI LF ++ L+LV+YI FKG W PFD T
Sbjct: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
Query: 218 EENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDK-GKMNTV 276
+ F++D+ +KVPMM + + D C ++++ Y GN T+ +L +K G +
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312
Query: 277 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQ 336
L+ D + W + + ++++ PK + Y++ ++L +MGI +F+ A+ S ++
Sbjct: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372
Query: 337 DAQ-LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSS 395
+ L+ S+V+ + V++++E G + + S P +++ ++PF MI++ +
Sbjct: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGML 432
Query: 396 LFLARVMNP 404
LFL RV+NP
Sbjct: 433 LFLGRVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 186 bits (471), Expect = 4e-47
Identities = 104/369 (28%), Positives = 199/369 (53%), Gaps = 5/369 (1%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
LA +F FSL + +++ N+ SP +S+A+ L LG G T Q+ +GL
Sbjct: 75 LAKETSNFGFSLLRK-ISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
Query: 99 ERSETEIHQG-FQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
+ ++ + F+ L + +++ L +T G+ F+ ++ E+F K Y+++E +
Sbjct: 134 KPTKPGLLPSLFKGLRETLSRN-LELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
Query: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
MNF++ + A R +N Y+ +T+GKI LF ++ L+LV+YI FKG W PFD T
Sbjct: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
Query: 218 EENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDK-GKMNTV 276
+ F++D+ +KVPMM + + D C ++++ Y GN T+ +L +K G +
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLAL 312
Query: 277 IAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQ 336
L+ D + W + + ++++ PK + Y++ ++L +MGI +F+ A+ S ++
Sbjct: 313 EDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSA 372
Query: 337 DAQ-LKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSS 395
+ L+ S+V+ + V++++E G + + S P +++ ++PF MI++ +
Sbjct: 373 TGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGML 432
Query: 396 LFLARVMNP 404
LFL RV+NP
Sbjct: 433 LFLGRVVNP 441
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 182 bits (463), Expect = 4e-46
Identities = 118/370 (31%), Positives = 190/370 (51%), Gaps = 11/370 (2%)
Query: 43 NVDFAFSLYKHLV-ALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGF----NL 97
N FAF+LY+ L ++ NIFI+PV IS A+ M+SLG G T Q+ L F N
Sbjct: 130 NAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNA 189
Query: 98 TERSE-TEIHQGFQHL-HQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEV 155
+ + E T IH F+ L H+LF ++ + N L++ +L F ++ YY +E
Sbjct: 190 SSKYEITTIHNLFRKLTHRLFRRN-FGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEA 248
Query: 156 LAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLAS 215
+F D A S+ N+++ T+G I D +D ++++N I+FKG+W F +
Sbjct: 249 QIADFSDPAFISKT-NNHIMKLTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEM 307
Query: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDK-GKMN 274
T NF ++E VVKV MM +D EL C ++Q+ YVG ++ ++P K M
Sbjct: 308 THNHNFRLNEREVVKVSMMQTKGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMK 367
Query: 275 TVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRI 334
T+ A L+ + RW +T+ ++ +PK + Y+L + L+ MGI LF N + I
Sbjct: 368 TLEAQLTPRVVERWQKSMTNRTREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGI 427
Query: 335 TQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWS 394
+ D ++ H+ + +NEEG T V S + ++PF+ +I++H T
Sbjct: 428 S-DQRIAIDLFKHQGTITVNEEGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSC 486
Query: 395 SLFLARVMNP 404
LF+ RV NP
Sbjct: 487 LLFMGRVANP 496
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 178 bits (452), Expect = 7e-45
Identities = 121/383 (31%), Positives = 202/383 (52%), Gaps = 17/383 (4%)
Query: 33 SNHHRGLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQG 92
S R A N +FA LY+ V+LS K NI SP+ I++ L M+ LG G + Q+ Q
Sbjct: 16 SQASRCSAQKNTEFAVDLYQE-VSLSHKDNIIFSPLGITLVLEMVQLGAKGKAQQQIRQT 74
Query: 93 LGFNLTERSETEIHQGFQHLHQLF-AKSDTSLEMT--MGNALFLDGSLELLESFSADIKH 149
L ++ ET + F L F A S+ E T + NAL+L + E + K
Sbjct: 75 L-----KQQETSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKE 129
Query: 150 YYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAI--LVLVNYIFFKGTW 207
+++S + ++FQD + I+++V+ KT GKI D+FSG + + LVLVN I+FKG W
Sbjct: 130 FFQSAIKLVDFQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDW 189
Query: 208 TQPFDLASTREENFYVDETTVVKVPMM--LQSSTISYLHDAELPCQLVQMNYVGNG-TVF 264
Q F T+ NF + VK+PMM L + Y ++ L Q+++++Y G+ ++
Sbjct: 190 KQKFRKEDTQLINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLI 249
Query: 265 FILPDKGK-MNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIAD 323
ILP +G + V ++ I +W + + +V++ +P+ + D DVL + I +
Sbjct: 250 IILPAEGMDIEEVEKLITAQQILKWLSEMQEEEVEISLPRFKVEQKVDFKDVLYSLNITE 309
Query: 324 LFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQ 381
+F+ + S IT +++ S+V K ++NE+G + A STG+ + + +F N
Sbjct: 310 IFSGGCDLSGITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIANH 369
Query: 382 PFIIMIFDHFTWSSLFLARVMNP 404
PF+ ++ + T S LF+ RV NP
Sbjct: 370 PFLFIMKHNPTESILFMGRVTNP 392
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 178 bits (451), Expect = 9e-45
Identities = 122/388 (31%), Positives = 207/388 (53%), Gaps = 23/388 (5%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGF--- 95
L+ AN F F L++ S + NIF SP+SI+ AL M+ LG +T Q+ + L F
Sbjct: 4 LSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQV 62
Query: 96 --NLTERSET-------EIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSAD 146
N TE++ T +H FQ L F KS + E+ + N LF + + + L+ +
Sbjct: 63 TENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDA 122
Query: 147 IKHYYESEVLAMNFQDWATASRQ-INSYVKNKTQGKIVDLFSG--LDSPAILVLVNYIFF 203
IK +Y++ V + +F + SR+ INS+V+++T KI +LF + + LVLVN I+F
Sbjct: 123 IKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYF 182
Query: 204 KGTWTQPFDLASTREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-T 262
KG W F +T+EE F+ ++ T V MM Q ++ ++ ++ +++++ Y G +
Sbjct: 183 KGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLS 242
Query: 263 VFFILPDK-GKMNTVIAALSRDTINRWSA--GLTSSQVDLYIPKVTISGVYDLGDVLEEM 319
+ +LP++ + + L+ + + W++ + + VDL++P+ + YDL D L M
Sbjct: 243 MIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTM 302
Query: 320 GIADLFTNQANFSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPII--- 376
G+ ++F A+ S +T L SKV+HKA +++ EEGV+ A +T V + S P
Sbjct: 303 GMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEE 362
Query: 377 LRFNQPFIIMIFDHFTWSSLFLARVMNP 404
N PF+ I + T S LF R +P
Sbjct: 363 FCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 176 bits (445), Expect = 4e-44
Identities = 122/380 (32%), Positives = 205/380 (53%), Gaps = 15/380 (3%)
Query: 39 LASANVDFAFSLYKHLV-ALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFN- 96
L+ AN FA + Y+HL + + NIF+SP+SIS A AM LG C T QL++ F+
Sbjct: 83 LSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDT 142
Query: 97 LTERSETEIHQGFQHLH-QLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEV 155
++E++ +IH F L+ +L+ K++ S ++ N LF D SL E++ + Y +++
Sbjct: 143 ISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVYGAKL 202
Query: 156 LAMNFQDWATASRQ-INSYVKNKTQGKIVDLF--SGLDSPAILVLVNYIFFKGTWTQPFD 212
++F++ A SR IN +V NKT+G+I D+ ++ +LVLVN I+FKG W F
Sbjct: 203 QPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWKSKFS 262
Query: 213 LASTREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDKG 271
+TR+E FY + MM Q Y AE Q++++ + G+ T+ ILP
Sbjct: 263 PENTRKELFYKADGESCSASMMYQEGKFRYRRVAE-GTQVLELPFKGDDITMVLILPKPE 321
Query: 272 K-MNTVIAALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFT-NQA 329
K + V L+ + + W L + +++P+ I + L + L++MG+ DLF+ ++
Sbjct: 322 KSLAKVEKELTPEVLQEWLDELEEMMLVVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKS 381
Query: 330 NFSRITQDAQ--LKSSKVVHKAVLQLNEEGVDTAGSTGVTL---NLTSKPIILRFNQPFI 384
I + + L S HKA L++NEEG + A ST V + +L + + N+PF+
Sbjct: 382 KLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFL 441
Query: 385 IMIFDHFTWSSLFLARVMNP 404
+ I + + +F+ RV NP
Sbjct: 442 VFIREVPLNTIIFMGRVANP 461
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 173 bits (439), Expect = 2e-43
Identities = 122/376 (32%), Positives = 193/376 (51%), Gaps = 15/376 (3%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
L AN FA SL+K L +N+F SP+SIS ALAM+ +G G T AQ+ Q L
Sbjct: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--- 60
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
+ +IH+GFQ L ++ T + N LF + + + L F + +Y++E+ +
Sbjct: 61 -YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEEL 119
Query: 159 NF-QDWATASRQINSYVKNKTQGKIVDLFSG--LDSPAILVLVNYIFFKGTWTQPFDLAS 215
+F +D + IN +V KT+GKI ++ +D LVLVN I+FKG W + FD
Sbjct: 120 SFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKY 179
Query: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDKG-KM 273
TR F +E V MM + + + E+ Q++++ YV ++ +LPD +
Sbjct: 180 TRGMLFKTNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDL 238
Query: 274 NTVIAALSRDTINRW--SAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTN-QAN 330
V AL+ + W S LT S+V +++P++ + YDL L +G+ D F +A+
Sbjct: 239 AVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKAD 298
Query: 331 FSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQPFIIMIF 388
FS ++ + + SKV HK +++NEEG + A +T V N + RF + PF+ I
Sbjct: 299 FSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIR 358
Query: 389 DHFTWSSLFLARVMNP 404
H T LF R +P
Sbjct: 359 HHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 173 bits (439), Expect = 2e-43
Identities = 122/376 (32%), Positives = 193/376 (51%), Gaps = 15/376 (3%)
Query: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
L AN FA SL+K L +N+F SP+SIS ALAM+ +G G T AQ+ Q L
Sbjct: 4 LCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCL--- 60
Query: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
+ +IH+GFQ L ++ T + N LF + + + L F + +Y++E+ +
Sbjct: 61 -YKDGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEEL 119
Query: 159 NF-QDWATASRQINSYVKNKTQGKIVDLFSG--LDSPAILVLVNYIFFKGTWTQPFDLAS 215
+F +D + IN +V KT+GKI ++ +D LVLVN I+FKG W + FD
Sbjct: 120 SFAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKY 179
Query: 216 TREENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNG-TVFFILPDKG-KM 273
TR F +E V MM + + + E+ Q++++ YV ++ +LPD +
Sbjct: 180 TRGMLFKTNEEKKT-VQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDL 238
Query: 274 NTVIAALSRDTINRW--SAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTN-QAN 330
V AL+ + W S LT S+V +++P++ + YDL L +G+ D F +A+
Sbjct: 239 AVVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKAD 298
Query: 331 FSRITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRF--NQPFIIMIF 388
FS ++ + + SKV HK +++NEEG + A +T V N + RF + PF+ I
Sbjct: 299 FSGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCADHPFLFFIR 358
Query: 389 DHFTWSSLFLARVMNP 404
H T LF R +P
Sbjct: 359 HHKTNCILFCGRFSSP 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,968,985
Number of Sequences: 37866
Number of extensions: 485131
Number of successful extensions: 1302
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1087
Number of HSP's gapped (non-prelim): 71
length of query: 405
length of database: 18,247,518
effective HSP length: 105
effective length of query: 300
effective length of database: 14,271,588
effective search space: 4281476400
effective search space used: 4281476400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.