Search of human proteins with 68299767

Search of human proteins with 68299767

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68299767 arylacetamide deacetylase [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68299767 arylacetamide deacetylase [Homo sapiens]                  813   0.0  
gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]          417   e-117
gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo sap...   332   3e-91
gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo sa...   327   1e-89
gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo sa...   246   3e-65
gi|226423950 arylacetamide deacetylase-like 1 isoform c [Homo sa...   246   3e-65
gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]           198   8e-51
gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo sa...   190   2e-48
gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo sa...   161   1e-39
gi|21328446 hormone-sensitive lipase [Homo sapiens]                    56   7e-08
gi|4557351 butyrylcholinesterase precursor [Homo sapiens]              45   1e-04
gi|148536848 carboxyl ester lipase precursor [Homo sapiens]            43   4e-04
gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]      42   7e-04
gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]      42   7e-04
gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]      42   7e-04
gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]                41   0.002
gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]                41   0.002
gi|7662470 neuroligin 1 [Homo sapiens]                                 41   0.002
gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo sa...    40   0.004
gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo sa...    40   0.004
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          32   1.3  
gi|98961141 transmembrane protein 168 [Homo sapiens]                   32   1.3  
gi|148539860 protein tyrosine phosphatase, receptor type, T isof...    31   2.3  
gi|148539858 protein tyrosine phosphatase, receptor type, T isof...    31   2.3  

>gi|68299767 arylacetamide deacetylase [Homo sapiens]
          Length = 399

 Score =  813 bits (2101), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD 60
           MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD
Sbjct: 1   MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD 60

Query: 61  SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA 120
           SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA
Sbjct: 61  SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA 120

Query: 121 ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP 180
           ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP
Sbjct: 121 ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP 180

Query: 181 ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF 240
           ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF
Sbjct: 181 ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF 240

Query: 241 LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP 300
           LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP
Sbjct: 241 LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP 300

Query: 301 NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG 360
           NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG
Sbjct: 301 NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG 360

Query: 361 VQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL 399
           VQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL
Sbjct: 361 VQVTHNHVEDGFHGAFSFLGLKISHRLINQYIEWLKENL 399


>gi|206597554 arylacetamide deacetylase-like 2 [Homo sapiens]
          Length = 401

 Score =  417 bits (1072), Expect = e-117
 Identities = 206/403 (51%), Positives = 283/403 (70%), Gaps = 6/403 (1%)

Query: 1   MGRKSLYLLIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMD 60
           MG K+L L ++ +L   + YTP+PDN+EE W++M ++A  KT    A   E + +  + +
Sbjct: 1   MGLKALCLGLLCVLFVSHFYTPMPDNIEESWKIMALDAIAKTCTFTAMCFENMRIMRYEE 60

Query: 61  SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSA 120
              ++   D   P SDE +TVT+T F +I VR+Y+PKRKSE  RR + Y HGGG+C GS+
Sbjct: 61  FISMIFRLDYTQPLSDEYITVTDTTFVDIPVRLYLPKRKSETRRRAVIYFHGGGFCFGSS 120

Query: 121 ALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNP 180
               +D L+RWTA+ LDAVVV  +YRLAP++HFP QFED   A+++FL +K+L KYGV+P
Sbjct: 121 KQRAFDFLNRWTANTLDAVVVGVDYRLAPQHHFPAQFEDGLAAVKFFLLEKILTKYGVDP 180

Query: 181 ERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLF 240
            RI I+GDS+GGNLA AVTQQ+ +D ++K K+K+Q L+YP LQ  D  LPS++EN + + 
Sbjct: 181 TRICIAGDSSGGNLATAVTQQVQNDAEIKHKIKMQVLLYPGLQITDSYLPSHRENEHGIV 240

Query: 241 LSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP 300
           L++ + ++  S YFT D +L  AM   QH+P+ES HLFKFVNWS LLPE++ K +VY  P
Sbjct: 241 LTRDVAIKLVSLYFTKDEALPWAMRRNQHMPLESRHLFKFVNWSILLPEKYRKDYVYTEP 300

Query: 301 NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTG 360
             G   L+   PG  D RA PLLA+D++L+ LPLTY++TCQ+DLLRDDGLMYVTRLRN G
Sbjct: 301 ILGG--LSYSLPGLTDSRALPLLANDSQLQNLPLTYILTCQHDLLRDDGLMYVTRLRNVG 358

Query: 361 VQVTHNHVEDGFHGAFSFLG----LKISHRLINQYIEWLKENL 399
           VQV H H+EDG HGA SF+     L++  R+ + Y+ WL +NL
Sbjct: 359 VQVVHEHIEDGIHGALSFMTSPFYLRLGLRIRDMYVSWLDKNL 401


>gi|68051721 arylacetamide deacetylase-like 1 isoform b [Homo
           sapiens]
          Length = 440

 Score =  332 bits (852), Expect = 3e-91
 Identities = 177/407 (43%), Positives = 252/407 (61%), Gaps = 10/407 (2%)

Query: 3   RKSLYLLIVGI-LIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGL-HHFMD 60
           R S  LL   + L AYY+Y PLP +V +PW++M ++A  +  Q ++  +  LGL HH + 
Sbjct: 34  RSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLA 93

Query: 61  SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYV-PKRKSEALRRGLFYIHGGGWCVGS 119
              ++ SF +    S   V VT+T F+ + VRV+  P +  E L+R + YIHGGGW + S
Sbjct: 94  LNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALAS 153

Query: 120 AALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVN 179
           A +  YD L    A+ L+AV+VS  YRL PK +FP Q  DV  A ++FL+ +VL KY V+
Sbjct: 154 AKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVD 213

Query: 180 PERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFL 239
           P RI ISGDSAGGNLAAA+ QQ   D  +K KLK+Q+LIYP LQ LD + PSYQ+N N  
Sbjct: 214 PGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTP 273

Query: 240 FLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLPERFIKGHV 296
            L + +MV++W +YF  +    +AM+   H  +   E++ +   +NW+SLLP  F K + 
Sbjct: 274 ILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYK 333

Query: 297 YNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRL 356
                 G++ + ++ P  LD R+APL+AD   L+ LP TY++TC++D+LRDDG+MY  RL
Sbjct: 334 PVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRL 393

Query: 357 RNTGVQVTHNHVEDGFHGAFSF----LGLKISHRLINQYIEWLKENL 399
            + GV+VT +H EDGFHG   F        +  R  N YI+WL +NL
Sbjct: 394 ESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL 440


>gi|226423947 arylacetamide deacetylase-like 1 isoform a [Homo
           sapiens]
          Length = 448

 Score =  327 bits (838), Expect = 1e-89
 Identities = 178/415 (42%), Positives = 253/415 (60%), Gaps = 18/415 (4%)

Query: 3   RKSLYLLIVGI-LIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGL-HHFMD 60
           R S  LL   + L AYY+Y PLP +V +PW++M ++A  +  Q ++  +  LGL HH + 
Sbjct: 34  RSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATFRGAQQVSNLIHYLGLSHHLLA 93

Query: 61  SFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYV-PKRKSEALRRGLFYIHGGGWCVGS 119
              ++ SF +    S   V VT+T F+ + VRV+  P +  E L+R + YIHGGGW + S
Sbjct: 94  LNFIIVSFGKKSAWSSAQVKVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALAS 153

Query: 120 AALSG--------YDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKK 171
           A+ S         YD L    A+ L+AV+VS  YRL PK +FP Q  DV  A ++FL+ +
Sbjct: 154 ASASWSPSDEIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPE 213

Query: 172 VLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPS 231
           VL KY V+P RI ISGDSAGGNLAAA+ QQ   D  +K KLK+Q+LIYP LQ LD + PS
Sbjct: 214 VLQKYMVDPGRICISGDSAGGNLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPS 273

Query: 232 YQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLP 288
           YQ+N N   L + +MV++W +YF  +    +AM+   H  +   E++ +   +NW+SLLP
Sbjct: 274 YQQNVNTPILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLP 333

Query: 289 ERFIKGHVYNNPNYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDD 348
             F K +       G++ + ++ P  LD R+APL+AD   L+ LP TY++TC++D+LRDD
Sbjct: 334 ASFTKNYKPVVQTTGNARIVQELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDD 393

Query: 349 GLMYVTRLRNTGVQVTHNHVEDGFHGAFSF----LGLKISHRLINQYIEWLKENL 399
           G+MY  RL + GV+VT +H EDGFHG   F        +  R  N YI+WL +NL
Sbjct: 394 GIMYAKRLESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL 448


>gi|226423952 arylacetamide deacetylase-like 1 isoform c [Homo
           sapiens]
          Length = 275

 Score =  246 bits (628), Expect = 3e-65
 Identities = 127/274 (46%), Positives = 177/274 (64%), Gaps = 7/274 (2%)

Query: 133 ADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
           A+ L+AV+VS  YRL PK +FP Q  DV  A ++FL+ +VL KY V+P RI ISGDSAGG
Sbjct: 2   AEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGG 61

Query: 193 NLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSE 252
           NLAAA+ QQ   D  +K KLK+Q+LIYP LQ LD + PSYQ+N N   L + +MV++W +
Sbjct: 62  NLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVD 121

Query: 253 YFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAK 309
           YF  +    +AM+   H  +   E++ +   +NW+SLLP  F K +       G++ + +
Sbjct: 122 YFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQ 181

Query: 310 KYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVE 369
           + P  LD R+APL+AD   L+ LP TY++TC++D+LRDDG+MY  RL + GV+VT +H E
Sbjct: 182 ELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFE 241

Query: 370 DGFHGAFSF----LGLKISHRLINQYIEWLKENL 399
           DGFHG   F        +  R  N YI+WL +NL
Sbjct: 242 DGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL 275


>gi|226423950 arylacetamide deacetylase-like 1 isoform c [Homo
           sapiens]
          Length = 275

 Score =  246 bits (628), Expect = 3e-65
 Identities = 127/274 (46%), Positives = 177/274 (64%), Gaps = 7/274 (2%)

Query: 133 ADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
           A+ L+AV+VS  YRL PK +FP Q  DV  A ++FL+ +VL KY V+P RI ISGDSAGG
Sbjct: 2   AEELNAVIVSIEYRLVPKVYFPEQIHDVVRATKYFLKPEVLQKYMVDPGRICISGDSAGG 61

Query: 193 NLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSE 252
           NLAAA+ QQ   D  +K KLK+Q+LIYP LQ LD + PSYQ+N N   L + +MV++W +
Sbjct: 62  NLAAALGQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNTPILPRYVMVKYWVD 121

Query: 253 YFTTDRSLEKAMLSRQHVPV---ESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAK 309
           YF  +    +AM+   H  +   E++ +   +NW+SLLP  F K +       G++ + +
Sbjct: 122 YFKGNYDFVQAMIVNNHTSLDVEEAAAVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQ 181

Query: 310 KYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVE 369
           + P  LD R+APL+AD   L+ LP TY++TC++D+LRDDG+MY  RL + GV+VT +H E
Sbjct: 182 ELPQLLDARSAPLIADQAVLQLLPKTYILTCEHDVLRDDGIMYAKRLESAGVEVTLDHFE 241

Query: 370 DGFHGAFSF----LGLKISHRLINQYIEWLKENL 399
           DGFHG   F        +  R  N YI+WL +NL
Sbjct: 242 DGFHGCMIFTSWPTNFSVGIRTRNSYIKWLDQNL 275


>gi|61966717 arylacetamide deacetylase-like 4 [Homo sapiens]
          Length = 407

 Score =  198 bits (503), Expect = 8e-51
 Identities = 126/396 (31%), Positives = 204/396 (51%), Gaps = 17/396 (4%)

Query: 9   LIVGILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSF 68
           + V  +  +++ T +P  ++ P ++ +++     +  L    E LG+       + +   
Sbjct: 19  VFVWAVFEHFLTTDIPATLQHPAKLRFLHCIFLYLVTLGNIFEKLGICSMPKFIRFL--H 76

Query: 69  DEVPPTSDENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLL 128
           D V    D  + VT+ +F  I VR++ PK  S   RRG+ + HGG    GS  L  Y  L
Sbjct: 77  DSVRIKKDPELVVTDLRFGTIPVRLFQPKAASSRPRRGIIFYHGGATVFGS--LDCYHGL 134

Query: 129 SRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGD 188
             + A   ++V++   YR  P +H P  F+D  NA   FL  K L  YGV+P R+ + G+
Sbjct: 135 CNYLARETESVLLMIGYRKLPDHHSPALFQDCMNASIHFL--KALETYGVDPSRVVVCGE 192

Query: 189 SAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVR 248
           S GG   AA+TQ L+   D+  +++ Q LIYP +Q   + LPS+Q+N N   LS+  MV 
Sbjct: 193 SVGGAAVAAITQALVGRSDLP-RIRAQVLIYPVVQAFCLQLPSFQQNQNVPLLSRKFMVT 251

Query: 249 FWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSL--LPERFI-KGHVYNNPNYGSS 305
               Y   D S   A+L+   VP +     K+  W S   +P++F  +G+   +P   + 
Sbjct: 252 SLCNYLAIDLSWRDAILNGTCVPPDVWR--KYEKWLSPDNIPKKFKNRGYQPWSPGPFNE 309

Query: 306 ELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTH 365
               +    LDV  +PL+ADD  +  LP  ++++C+ D+LRDD L+Y  RL + GV+VT 
Sbjct: 310 AAYLEAKHMLDVENSPLIADDEVIAQLPEAFLVSCENDILRDDSLLYKKRLEDQGVRVTW 369

Query: 366 NHVEDGFHGAFSF-----LGLKISHRLINQYIEWLK 396
            H+ DGFHG+  F     L    S +++N  + ++K
Sbjct: 370 YHLYDGFHGSIIFFDKKALSFPCSLKIVNAVVSYIK 405


>gi|157041239 arylacetamide deacetylase-like 3 isoform 1 [Homo
           sapiens]
          Length = 350

 Score =  190 bits (483), Expect = 2e-48
 Identities = 118/334 (35%), Positives = 187/334 (55%), Gaps = 12/334 (3%)

Query: 70  EVPPTS-DENVTVTETKFNNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLL 128
           ++PP   D +V VT+ +F  I V++Y  K  +  L+ G+ Y HGGG  +GS   + + + 
Sbjct: 20  DLPPLKYDPDVVVTDFRFGTIPVKLYQSKASTCTLKPGIVYYHGGGGVMGSLK-THHGIC 78

Query: 129 SRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGD 188
           SR   +  D+VV++  YR  PK+ FP+   D   A   FL  K L  YGV+P R+ + GD
Sbjct: 79  SRLCKES-DSVVLAVGYRKLPKHKFPVPVRDCLVATIHFL--KSLDAYGVDPARVVVCGD 135

Query: 189 SAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVR 248
           S GG +AA V QQL+D PD+  +++ Q LIY  LQ LD+  PS+Q+  N   L+ S +  
Sbjct: 136 SFGGAIAAVVCQQLVDRPDLP-RIRAQILIYAILQALDLQTPSFQQRKNIPLLTWSFICY 194

Query: 249 FWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELA 308
            + +      S ++ ++   H+P E    ++       +PERF +      P+   +E A
Sbjct: 195 CFFQNLDFSSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERGYQLKPHEPMNEAA 254

Query: 309 -KKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNH 367
             +    LDV  +PL+A+D+ +  LP T +++C+YD LRD+ L+Y  RL + GV VT +H
Sbjct: 255 YLEVSVVLDVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHH 314

Query: 368 VEDGFHGA-----FSFLGLKISHRLINQYIEWLK 396
           +EDGFHG       SFL    S R+++  ++++K
Sbjct: 315 MEDGFHGVLRTIDMSFLHFPCSMRILSALVQFVK 348


>gi|157041237 arylacetamide deacetylase-like 3 isoform 2 [Homo
           sapiens]
          Length = 280

 Score =  161 bits (407), Expect = 1e-39
 Identities = 96/266 (36%), Positives = 150/266 (56%), Gaps = 9/266 (3%)

Query: 137 DAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAA 196
           D+VV++  YR  PK+ FP+   D   A   FL  K L  YGV+P R+ + GDS GG +AA
Sbjct: 16  DSVVLAVGYRKLPKHKFPVPVRDCLVATIHFL--KSLDAYGVDPARVVVCGDSFGGAIAA 73

Query: 197 AVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTT 256
            V QQL+D PD+  +++ Q LIY  LQ LD+  PS+Q+  N   L+ S +   + +    
Sbjct: 74  VVCQQLVDRPDLP-RIRAQILIYAILQALDLQTPSFQQRKNIPLLTWSFICYCFFQNLDF 132

Query: 257 DRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNPNYGSSELAK-KYPGFL 315
             S ++ ++   H+P E    ++       +PERF +      P+   +E A  +    L
Sbjct: 133 SSSWQEVIMKGAHLPAEVWEKYRKWLGPENIPERFKERGYQLKPHEPMNEAAYLEVSVVL 192

Query: 316 DVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGA 375
           DV  +PL+A+D+ +  LP T +++C+YD LRD+ L+Y  RL + GV VT +H+EDGFHG 
Sbjct: 193 DVMCSPLIAEDDIVSQLPETCIVSCEYDALRDNSLLYKKRLEDLGVPVTWHHMEDGFHGV 252

Query: 376 -----FSFLGLKISHRLINQYIEWLK 396
                 SFL    S R+++  ++++K
Sbjct: 253 LRTIDMSFLHFPCSMRILSALVQFVK 278


>gi|21328446 hormone-sensitive lipase [Homo sapiens]
          Length = 1076

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 36/92 (39%), Positives = 49/92 (53%), Gaps = 4/92 (4%)

Query: 107 LFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRW 166
           + + HGGG+ V   + S    L  W A  L A ++S +Y LAP+  FP   E+ + A  W
Sbjct: 647 IVHFHGGGF-VAQTSRSHEPYLKSW-AQELGAPIISIDYSLAPEAPFPRALEECFFAYCW 704

Query: 167 FLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198
            +  K  A  G   ERI ++GDSAGGNL   V
Sbjct: 705 AI--KHCALLGSTGERICLAGDSAGGNLCFTV 734



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 26/62 (41%), Positives = 35/62 (56%)

Query: 320  APLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSFL 379
            +PLLA D+ L+ LP  +++ C  D + DD +M   RLRN G  VT   VED  HG  +  
Sbjct: 971  SPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLA 1030

Query: 380  GL 381
             L
Sbjct: 1031 AL 1032


>gi|4557351 butyrylcholinesterase precursor [Homo sapiens]
          Length = 602

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/123 (31%), Positives = 64/123 (52%), Gaps = 20/123 (16%)

Query: 91  VRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLA-- 148
           V +  PK K+  +   L +I+GGG+  G+++L  YD   ++ A     +VVS NYR+   
Sbjct: 125 VWIPAPKPKNATV---LIWIYGGGFQTGTSSLHVYD--GKFLARVERVIVVSMNYRVGAL 179

Query: 149 --------PKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQ 200
                   P+    +   D   AL+W   +K +A +G NP+ + + G+SAG   AA+V+ 
Sbjct: 180 GFLALPGNPEAPGNMGLFDQQLALQWV--QKNIAAFGGNPKSVTLFGESAG---AASVSL 234

Query: 201 QLL 203
            LL
Sbjct: 235 HLL 237


>gi|148536848 carboxyl ester lipase precursor [Homo sapiens]
          Length = 756

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 45/172 (26%), Positives = 80/172 (46%), Gaps = 27/172 (15%)

Query: 89  ILVRVYVPKRKSEALRR--GLFYIHGGGWCVGSAA----LSGYDLLSRWTADRLDAVVVS 142
           + + ++VP+ + +  R    + +I+GG + +GS      L+ Y       A R + +VV+
Sbjct: 104 LYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEIATRGNVIVVT 163

Query: 143 TNYRLAP-------KYHFPIQF--EDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGN 193
            NYR+ P         + P  +   D + A+ W   K+ +A +G +P  I + G+SAGG 
Sbjct: 164 FNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWV--KRNIAAFGGDPNNITLFGESAGG- 220

Query: 194 LAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSL 245
             A+V+ Q L   +       + LI  A+    V L  +    N LF +K +
Sbjct: 221 --ASVSLQTLSPYN-------KGLIRRAISQSGVALSPWVIQKNPLFWAKKV 263


>gi|68508967 carboxylesterase 1 isoform a precursor [Homo sapiens]
          Length = 568

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)

Query: 89  ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
           + + +Y P   ++  R  +  +IHGGG  VG+A  S YD L+   A   + VVV+  YRL
Sbjct: 118 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 173

Query: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
                F    E         D   ALRW   +  +A +G NP  + I G+SAGG
Sbjct: 174 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 225


>gi|68508965 carboxylesterase 1 isoform b precursor [Homo sapiens]
          Length = 567

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)

Query: 89  ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
           + + +Y P   ++  R  +  +IHGGG  VG+A  S YD L+   A   + VVV+  YRL
Sbjct: 117 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 172

Query: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
                F    E         D   ALRW   +  +A +G NP  + I G+SAGG
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 224


>gi|68508957 carboxylesterase 1 isoform c precursor [Homo sapiens]
          Length = 566

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 16/114 (14%)

Query: 89  ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
           + + +Y P   ++  R  +  +IHGGG  VG+A  S YD L+   A   + VVV+  YRL
Sbjct: 117 LYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAA--STYDGLA--LAAHENVVVVTIQYRL 172

Query: 148 APKYHFPIQFE---------DVYNALRWFLRKKVLAKYGVNPERIGISGDSAGG 192
                F    E         D   ALRW   +  +A +G NP  + I G+SAGG
Sbjct: 173 GIWGFFSTGDEHSRGNWGHLDQVAALRWV--QDNIASFGGNPGSVTIFGESAGG 224


>gi|37622887 carboxylesterase 2 isoform 2 [Homo sapiens]
          Length = 607

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 16/120 (13%)

Query: 89  ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
           + + +Y P    E     +  +IHGG    G A+L    +L+       + VVV   YRL
Sbjct: 188 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE----NVVVVIIQYRL 243

Query: 148 APKYHFPIQ---------FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198
                F            + D   ALRW  +   +A +G NP+R+ I G+SAGG   +++
Sbjct: 244 GVLGFFSTGDKHATGNWGYLDQVAALRWVQQN--IAHFGGNPDRVTIFGESAGGTSVSSL 301


>gi|37622885 carboxylesterase 2 isoform 1 [Homo sapiens]
          Length = 623

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 16/120 (13%)

Query: 89  ILVRVYVPKRKSEALRRGLF-YIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRL 147
           + + +Y P    E     +  +IHGG    G A+L    +L+       + VVV   YRL
Sbjct: 188 LYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE----NVVVVIIQYRL 243

Query: 148 APKYHFPIQ---------FEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198
                F            + D   ALRW  +   +A +G NP+R+ I G+SAGG   +++
Sbjct: 244 GVLGFFSTGDKHATGNWGYLDQVAALRWVQQN--IAHFGGNPDRVTIFGESAGGTSVSSL 301


>gi|7662470 neuroligin 1 [Homo sapiens]
          Length = 823

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 23/126 (18%)

Query: 89  ILVRVYVPK----RKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTN 144
           + + +YVP     R S   +  + YIHGG +  G+  L    +L+ +     + +V++ N
Sbjct: 154 LYLNIYVPTEDDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYG----NVIVITVN 209

Query: 145 YRL-----------APKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGN 193
           YRL           A K ++ +   D+  ALRW    + +  +G +P RI + G  AGG+
Sbjct: 210 YRLGVLGFLSTGDQAAKGNYGLL--DLIQALRW--TSENIGFFGGDPLRITVFGSGAGGS 265

Query: 194 LAAAVT 199
               +T
Sbjct: 266 CVNLLT 271


>gi|4557239 acetylcholinesterase isoform E4-E6 precursor [Homo
           sapiens]
          Length = 614

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 17/128 (13%)

Query: 89  ILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYR-- 146
           + + V+ P  +  +    L +I+GGG+  G+++L  YD   R+       V+VS NYR  
Sbjct: 128 LYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYD--GRFLVQAERTVLVSMNYRVG 185

Query: 147 ------LAPKYHFP--IQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198
                 L      P  +   D   AL+W   ++ +A +G +P  + + G+SAG   AA+V
Sbjct: 186 AFGFLALPGSREAPGNVGLLDQRLALQWV--QENVAAFGGDPTSVTLFGESAG---AASV 240

Query: 199 TQQLLDDP 206
              LL  P
Sbjct: 241 GMHLLSPP 248


>gi|7710112 acetylcholinesterase isoform E4-E5 precursor [Homo
           sapiens]
          Length = 617

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/128 (28%), Positives = 61/128 (47%), Gaps = 17/128 (13%)

Query: 89  ILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYR-- 146
           + + V+ P  +  +    L +I+GGG+  G+++L  YD   R+       V+VS NYR  
Sbjct: 128 LYLNVWTPYPRPTSPTPVLVWIYGGGFYSGASSLDVYD--GRFLVQAERTVLVSMNYRVG 185

Query: 147 ------LAPKYHFP--IQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAV 198
                 L      P  +   D   AL+W   ++ +A +G +P  + + G+SAG   AA+V
Sbjct: 186 AFGFLALPGSREAPGNVGLLDQRLALQWV--QENVAAFGGDPTSVTLFGESAG---AASV 240

Query: 199 TQQLLDDP 206
              LL  P
Sbjct: 241 GMHLLSPP 248


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 18/60 (30%), Positives = 29/60 (48%)

Query: 25 DNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVPPTSDENVTVTET 84
          D + +P R ++I A    I      V+L+   H  D+F  V    +VP   D + T+TE+
Sbjct: 8  DLLSQPCRAVYIFAKKNDIPFELRIVDLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTES 67


>gi|98961141 transmembrane protein 168 [Homo sapiens]
          Length = 697

 Score = 31.6 bits (70), Expect = 1.3
 Identities = 31/130 (23%), Positives = 56/130 (43%), Gaps = 25/130 (19%)

Query: 87  NNILVRVYVPKRKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNY- 145
           N I + +++     E++  GLF  H  G C+G  ++ GY            A+V+ TN+ 
Sbjct: 379 NGIFLSMFLIVLPLESMAHGLF--HELGNCLGGTSV-GY------------AIVIPTNFC 423

Query: 146 ------RLAPKYHFP---IQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAA 196
                  L P  H     ++   + NA++ F    ++  YG +    G+S D+    L A
Sbjct: 424 SPDGQPTLLPPEHVQELNLRSTGMLNAIQRFFAYHMIETYGCDYSTSGLSFDTLHSKLKA 483

Query: 197 AVTQQLLDDP 206
            +  + +D P
Sbjct: 484 FLELRTVDGP 493


>gi|148539860 protein tyrosine phosphatase, receptor type, T isoform 2
            precursor [Homo sapiens]
          Length = 1441

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 14/104 (13%)

Query: 17   YYIYT--PLPDNVEEPWRMMW--INAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVP 72
            +YI T  P+ + V++ WRM+W   +A +  + NL     +  + ++ D  +V G      
Sbjct: 956  HYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYG------ 1009

Query: 73   PTSDENVTVTETK-FNNILVRVYVPKRKSEALRRGLFYIHGGGW 115
               D  VT+ ET+     ++R +  ++K     R L   H   W
Sbjct: 1010 ---DIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSW 1050


>gi|148539858 protein tyrosine phosphatase, receptor type, T isoform 1
            precursor [Homo sapiens]
          Length = 1460

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 26/104 (25%), Positives = 47/104 (45%), Gaps = 14/104 (13%)

Query: 17   YYIYT--PLPDNVEEPWRMMW--INAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVP 72
            +YI T  P+ + V++ WRM+W   +A +  + NL     +  + ++ D  +V G      
Sbjct: 975  HYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRVKCVRYWPDDTEVYG------ 1028

Query: 73   PTSDENVTVTETK-FNNILVRVYVPKRKSEALRRGLFYIHGGGW 115
               D  VT+ ET+     ++R +  ++K     R L   H   W
Sbjct: 1029 ---DIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSW 1069


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,485,792
Number of Sequences: 37866
Number of extensions: 603539
Number of successful extensions: 1334
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1288
Number of HSP's gapped (non-prelim): 27
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.