Guide to the Human Genome
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Search of human proteins with 67089167

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67089167 LETM1 domain containing 1 isoform 2 [Homo sapiens]
         (304 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67089167 LETM1 domain containing 1 isoform 2 [Homo sapiens]        627   e-180
gi|67089165 LETM1 domain containing 1 isoform 1 [Homo sapiens]        627   e-180
gi|6912482 leucine zipper-EF-hand containing transmembrane prote...    64   2e-10
gi|21389523 leucine zipper-EF-hand containing transmembrane prot...    51   1e-06
gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]        33   0.31 
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]          31   1.6  
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]          31   1.6  
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]          31   1.6  
gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens]      31   1.6  
gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Hom...    30   2.6  
gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo sapi...    29   5.9  
gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo sapi...    29   5.9  
gi|7706704 G protein-coupled receptor 89B [Homo sapiens]               29   5.9  
gi|148234741 G protein-coupled receptor 89C [Homo sapiens]             29   5.9  

>gi|67089167 LETM1 domain containing 1 isoform 2 [Homo sapiens]
          Length = 304

 Score =  627 bits (1616), Expect = e-180
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK 60
           MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK
Sbjct: 1   MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK 60

Query: 61  FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ 120
           FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ
Sbjct: 61  FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ 120

Query: 121 TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR 180
           TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR
Sbjct: 121 TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR 180

Query: 181 ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG 240
           ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG
Sbjct: 181 ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG 240

Query: 241 QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL 300
           QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL
Sbjct: 241 QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL 300

Query: 301 GTRR 304
           GTRR
Sbjct: 301 GTRR 304


>gi|67089165 LETM1 domain containing 1 isoform 1 [Homo sapiens]
          Length = 360

 Score =  627 bits (1616), Expect = e-180
 Identities = 304/304 (100%), Positives = 304/304 (100%)

Query: 1   MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK 60
           MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK
Sbjct: 57  MSYVVTKTKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKARRIKTNMWKHNIK 116

Query: 61  FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ 120
           FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ
Sbjct: 117 FHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLLMYLFPRQLLIRHFWTPKQQ 176

Query: 121 TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR 180
           TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR
Sbjct: 177 TDFLDIYHAFRKQSHPEIISYLEKVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALR 236

Query: 181 ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG 240
           ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG
Sbjct: 237 ECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIG 296

Query: 241 QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL 300
           QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL
Sbjct: 297 QLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEWLQISCSLKEAELSLLLHNVVLLSTNYL 356

Query: 301 GTRR 304
           GTRR
Sbjct: 357 GTRR 360


>gi|6912482 leucine zipper-EF-hand containing transmembrane protein
           1 [Homo sapiens]
          Length = 739

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 66/266 (24%), Positives = 118/266 (44%), Gaps = 22/266 (8%)

Query: 33  FMKGLQMLWADAKKARRIKTNMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPP 92
           +  G ++LW D K A R+   +W+  +  H L  RE     +   D+ + +   +  + P
Sbjct: 164 YYHGFRLLWIDTKIAARM---LWRI-LNGHSLTRRERRQFLRICADLFRLVPFLVFVVVP 219

Query: 93  FANYLVFLLMYLFPRQLLIRHFWTPKQQTDFLDIYHAFRKQSHP--EIISYLEKVIP--- 147
           F  +L+ + + LFP  +L   F T   + + L      +K+     E+  +L+  I    
Sbjct: 220 FMEFLLPVAVKLFPN-MLPSTFETQSLKEERL------KKELRVKLELAKFLQDTIEEMA 272

Query: 148 LISDAGLRWRLTDLCTKIQR----GTHPAIHDILALRECFSNHPLGMNQLQALHVKALSR 203
           L + A       D     Q+    G  P+  +I+   + F +  L ++ L    + AL +
Sbjct: 273 LKNKAAKGSATKDFSVFFQKIRETGERPSNEEIMRFSKLFEDE-LTLDNLTRPQLVALCK 331

Query: 204 AMLLTSYLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNSTHIGE 263
            + L S      LR +L      I   DK +A+ G+  L  +E+++AC  RG+ +  + E
Sbjct: 332 LLELQSIGTNNFLRFQLTMRLRSIKADDKLIAEEGVDSLNVKELQAACRARGMRALGVTE 391

Query: 264 DRCRTWLGEWLQISCSLKEAELSLLL 289
           DR R  L +WL +    +E   SLL+
Sbjct: 392 DRLRGQLKQWLDLHLH-QEIPTSLLI 416


>gi|21389523 leucine zipper-EF-hand containing transmembrane protein
           2 [Homo sapiens]
          Length = 396

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 1/117 (0%)

Query: 157 RLTDLCTKIQRGTHPAIHDILALRECFSNHPLGMNQLQALHVKALSRAMLLTSYLPPPLL 216
           +L+    ++Q G  P+  +I+   + F +  L +  L    + AL + + L ++    LL
Sbjct: 159 QLSSYVKQVQTGHKPSTKEIVRFSKLFEDQ-LALEHLDRPQLVALCKLLELQTFGTNNLL 217

Query: 217 RHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNSTHIGEDRCRTWLGEW 273
           R +L      I   D+ +AK G+  L+  E+++AC  RG+ S  + E++ R  L EW
Sbjct: 218 RFQLLMKLKSIKADDEIIAKEGVTALSVSELQAACRARGMRSLGLTEEQLRQQLTEW 274


>gi|210147522 zinc finger, SWIM-type containing 6 [Homo sapiens]
          Length = 1215

 Score = 33.1 bits (74), Expect = 0.31
 Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 5/57 (8%)

Query: 158  LTDLCTKIQRGTHPAIHDILALRECFSNHPLGMNQLQA---LHVKALSRAMLLTSYL 211
            +T L     + THPAI+D+  L  C  +H LG N+L A   L VK++  A +L+  L
Sbjct: 1054 MTHLNLSYNQDTHPAINDV--LWACALSHSLGKNELAAIIPLVVKSVKCATVLSDIL 1108


>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
          Length = 504

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 10/77 (12%)

Query: 210 YLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNS-THIGEDRCRT 268
           YLP PL+ H  +  T  IH L   L      +++A+   S  Y R L    H  ED    
Sbjct: 412 YLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASI 471

Query: 269 WLGEWLQISCSLKEAEL 285
           +         SLKE +L
Sbjct: 472 F---------SLKEIQL 479


>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 10/77 (12%)

Query: 210 YLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNS-THIGEDRCRT 268
           YLP PL+ H  +  T  IH L   L      +++A+   S  Y R L    H  ED    
Sbjct: 382 YLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASI 441

Query: 269 WLGEWLQISCSLKEAEL 285
           +         SLKE +L
Sbjct: 442 F---------SLKEIQL 449


>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 10/77 (12%)

Query: 210 YLPPPLLRHRLKTHTTVIHQLDKALAKLGIGQLTAQEVKSACYLRGLNS-THIGEDRCRT 268
           YLP PL+ H  +  T  IH L   L      +++A+   S  Y R L    H  ED    
Sbjct: 382 YLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASI 441

Query: 269 WLGEWLQISCSLKEAEL 285
           +         SLKE +L
Sbjct: 442 F---------SLKEIQL 449


>gi|149944451 zinc finger, SWIM domain containing 5 [Homo sapiens]
          Length = 1185

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 20/46 (43%), Positives = 28/46 (60%), Gaps = 5/46 (10%)

Query: 169  THPAIHDILALRECFSNHPLGMNQLQA---LHVKALSRAMLLTSYL 211
            THPAI+D+  L  C  +H LG N+L A   L VK++  A +L+  L
Sbjct: 1035 THPAINDV--LWACALSHSLGKNELAALIPLVVKSVHCATVLSDIL 1078


>gi|55749644 UHRF1 (ICBP90) binding protein 1-like isoform a [Homo
            sapiens]
          Length = 1464

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 16/70 (22%), Positives = 39/70 (55%), Gaps = 2/70 (2%)

Query: 132  KQSHPEIISYLE-KVIPLISDAGLRWRLTDLCTKIQRGTHPAIHDILALRECFSNHPLGM 190
            +++H +++S +  K+  +  +  +R   T++C ++ + T   + +I +LR    N P+G 
Sbjct: 1183 QENHDDLMSVVVFKITGVNGEIDIRGEDTEICLQVNQVTPDQLGNI-SLRHYLCNRPVGS 1241

Query: 191  NQLQALHVKA 200
            +Q   +H K+
Sbjct: 1242 DQKAVIHSKS 1251


>gi|148229509 G protein-coupled receptor 89A isoform 2 [Homo
           sapiens]
          Length = 335

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 23/125 (18%)

Query: 8   TKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKAR---------------RIKT 52
           +K   GKY  FLG +F   Y ++ IFM  + +++    K                 +   
Sbjct: 158 SKTFKGKYFNFLG-YFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDV 216

Query: 53  NMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLL-----MYLFPR 107
             W  +I F  +    +  +R     +TK  F   IS    +N +V LL     MY    
Sbjct: 217 KFWSQHISFILVGIIIVTSIRGLLITLTK--FFYAISSSKSSNVIVLLLAQIMGMYFVSS 274

Query: 108 QLLIR 112
            LLIR
Sbjct: 275 VLLIR 279


>gi|148228819 G protein-coupled receptor 89A isoform 1 [Homo
           sapiens]
          Length = 455

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 23/125 (18%)

Query: 8   TKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKAR---------------RIKT 52
           +K   GKY  FLG +F   Y ++ IFM  + +++    K                 +   
Sbjct: 278 SKTFKGKYFNFLG-YFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDV 336

Query: 53  NMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLL-----MYLFPR 107
             W  +I F  +    +  +R     +TK  F   IS    +N +V LL     MY    
Sbjct: 337 KFWSQHISFILVGIIIVTSIRGLLITLTK--FFYAISSSKSSNVIVLLLAQIMGMYFVSS 394

Query: 108 QLLIR 112
            LLIR
Sbjct: 395 VLLIR 399


>gi|7706704 G protein-coupled receptor 89B [Homo sapiens]
          Length = 455

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 23/125 (18%)

Query: 8   TKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKAR---------------RIKT 52
           +K   GKY  FLG +F   Y ++ IFM  + +++    K                 +   
Sbjct: 278 SKTFKGKYFNFLG-YFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDV 336

Query: 53  NMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLL-----MYLFPR 107
             W  +I F  +    +  +R     +TK  F   IS    +N +V LL     MY    
Sbjct: 337 KFWSQHISFILVGIIIVTSIRGLLITLTK--FFYAISSSKSSNVIVLLLAQIMGMYFVSS 394

Query: 108 QLLIR 112
            LLIR
Sbjct: 395 VLLIR 399


>gi|148234741 G protein-coupled receptor 89C [Homo sapiens]
          Length = 320

 Score = 28.9 bits (63), Expect = 5.9
 Identities = 32/125 (25%), Positives = 48/125 (38%), Gaps = 23/125 (18%)

Query: 8   TKAINGKYHRFLGRHFPRFYVLYTIFMKGLQMLWADAKKAR---------------RIKT 52
           +K   GKY  FLG +F   Y ++ IFM  + +++    K                 +   
Sbjct: 143 SKTFKGKYFNFLG-YFFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDV 201

Query: 53  NMWKHNIKFHQLPYREMEHLRQFRQDVTKCLFLGIISIPPFANYLVFLL-----MYLFPR 107
             W  +I F  +    +  +R     +TK  F   IS    +N +V LL     MY    
Sbjct: 202 KFWSQHISFILVGIIIVTSIRGLLITLTK--FFYAISSSKSSNVIVLLLAQIMGMYFVSS 259

Query: 108 QLLIR 112
            LLIR
Sbjct: 260 VLLIR 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,288,902
Number of Sequences: 37866
Number of extensions: 459793
Number of successful extensions: 1184
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1172
Number of HSP's gapped (non-prelim): 16
length of query: 304
length of database: 18,247,518
effective HSP length: 102
effective length of query: 202
effective length of database: 14,385,186
effective search space: 2905807572
effective search space used: 2905807572
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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