Search of human proteins with 50959176

Search of human proteins with 50959176

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|50959176 PTX1 protein [Homo sapiens]
         (377 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|50959176 PTX1 protein [Homo sapiens]                               765   0.0  
gi|7706278 serologically defined breast cancer antigen 84 isofor...   181   1e-45
gi|38327615 serologically defined breast cancer antigen 84 isofo...   180   2e-45
gi|72534712 endoplasmic reticulum-golgi intermediate compartment...    77   2e-14
gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]                  33   0.42 
gi|4501913 ADAM metallopeptidase domain 23 preproprotein [Homo s...    30   3.6  
gi|208609993 methionine sulfoxide reductase A isoform b [Homo sa...    29   7.9  

>gi|50959176 PTX1 protein [Homo sapiens]
          Length = 377

 Score =  765 bits (1975), Expect = 0.0
 Identities = 377/377 (100%), Positives = 377/377 (100%)

Query: 1   MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWM 60
           MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWM
Sbjct: 1   MRRLNRKKTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWM 60

Query: 61  KYEYEVDKDFSSKLRINIDITVAMKCQYVGADVLDLAETMVASADGLVYEPTVFDLSPQQ 120
           KYEYEVDKDFSSKLRINIDITVAMKCQYVGADVLDLAETMVASADGLVYEPTVFDLSPQQ
Sbjct: 61  KYEYEVDKDFSSKLRINIDITVAMKCQYVGADVLDLAETMVASADGLVYEPTVFDLSPQQ 120

Query: 121 KEWQRMLQLIQSRLQEEHSLQDVIFKSAFKSTSTALPPREDDSSQSPNACRIHGHLYVNK 180
           KEWQRMLQLIQSRLQEEHSLQDVIFKSAFKSTSTALPPREDDSSQSPNACRIHGHLYVNK
Sbjct: 121 KEWQRMLQLIQSRLQEEHSLQDVIFKSAFKSTSTALPPREDDSSQSPNACRIHGHLYVNK 180

Query: 181 VAGNFHITVGKAIPHPRGHAHLAALVNHESYNFSHRIDHLSFGELVPAIINPLDGTEKIA 240
           VAGNFHITVGKAIPHPRGHAHLAALVNHESYNFSHRIDHLSFGELVPAIINPLDGTEKIA
Sbjct: 181 VAGNFHITVGKAIPHPRGHAHLAALVNHESYNFSHRIDHLSFGELVPAIINPLDGTEKIA 240

Query: 241 IDHNQMFQYFITVVPTKLHTYKISADTHQFSVTERERIINHAAGSHGVSGIFMKYDLSSL 300
           IDHNQMFQYFITVVPTKLHTYKISADTHQFSVTERERIINHAAGSHGVSGIFMKYDLSSL
Sbjct: 241 IDHNQMFQYFITVVPTKLHTYKISADTHQFSVTERERIINHAAGSHGVSGIFMKYDLSSL 300

Query: 301 MVTVTEEHMPFWQFFVRLCGIVGGIFSTTGMLHGIGKFIVEIICCRFRLGSYKPVNSVPF 360
           MVTVTEEHMPFWQFFVRLCGIVGGIFSTTGMLHGIGKFIVEIICCRFRLGSYKPVNSVPF
Sbjct: 301 MVTVTEEHMPFWQFFVRLCGIVGGIFSTTGMLHGIGKFIVEIICCRFRLGSYKPVNSVPF 360

Query: 361 EDGHTDNHLPLLENNTH 377
           EDGHTDNHLPLLENNTH
Sbjct: 361 EDGHTDNHLPLLENNTH 377


>gi|7706278 serologically defined breast cancer antigen 84 isoform b
           [Homo sapiens]
          Length = 383

 Score =  181 bits (458), Expect = 1e-45
 Identities = 119/368 (32%), Positives = 179/368 (48%), Gaps = 44/368 (11%)

Query: 8   KTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVD 67
           + L  +K+ DA+PK  E +   +  G TV++++   M LL + E   Y  T +  E  VD
Sbjct: 2   EALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVD 61

Query: 68  KDFSSKLRINIDITVA-MKCQYVGADVLDLAETMVASADGLVY----------------- 109
           K    KL+INID+    M C Y+  D +D+A       +  ++                 
Sbjct: 62  KSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAER 121

Query: 110 ------EPTVFDLSPQQKEWQRMLQLIQSRLQEE---HSLQDV--IFKS---AFKSTSTA 155
                 E TVFD  P   +  R      +  ++    ++ +DV   ++    AFK+  T 
Sbjct: 122 HELGKVEVTVFD--PDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTI 179

Query: 156 LPPREDDSSQSPN-----ACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHES 210
              R +  SQ         C+++G L VNKVAGNFH   GK+      H H       ++
Sbjct: 180 EQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHDLQSFGLDN 239

Query: 211 YNFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPTKLHTYKISAD---T 267
            N +H I HLSFGE  P I+NPLD T   A   + MFQYF+ VVPT     K+  +   T
Sbjct: 240 INMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVY--MKVDGEVLRT 297

Query: 268 HQFSVTERERIINHAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIVGGIFS 327
           +QFSVT  E++ N   G  G+ G+F+ Y+LS +MV +TE+H  F  F   +C I+GG+F+
Sbjct: 298 NQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAIIGGMFT 357

Query: 328 TTGMLHGI 335
             G++  +
Sbjct: 358 VAGLIDSL 365


>gi|38327615 serologically defined breast cancer antigen 84 isoform
           a [Homo sapiens]
          Length = 388

 Score =  180 bits (456), Expect = 2e-45
 Identities = 120/373 (32%), Positives = 182/373 (48%), Gaps = 49/373 (13%)

Query: 8   KTLSLVKELDAFPKVPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVD 67
           + L  +K+ DA+PK  E +   +  G TV++++   M LL + E   Y  T +  E  VD
Sbjct: 2   EALGKLKQFDAYPKTLEDFRVKTCGGATVTIVSGLLMLLLFLSELQYYLTTEVHPELYVD 61

Query: 68  KDFSSKLRINIDITVA-MKCQYVGADVLDLAETMVASADGLVY----------------- 109
           K    KL+INID+    M C Y+  D +D+A       +  ++                 
Sbjct: 62  KSRGDKLKINIDVLFPHMPCAYLSIDAMDVAGEQQLDVEHNLFKQRLDKDGIPVSSEAER 121

Query: 110 ------EPTVFDLSPQQKEWQRMLQLIQSRLQEE---HSLQDV--IFKS---AFKSTSTA 155
                 E TVFD  P   +  R      +  ++    ++ +DV   ++    AFK+  T 
Sbjct: 122 HELGKVEVTVFD--PDSLDPDRCESCYGAEAEDIKCCNTCEDVREAYRRRGWAFKNPDTI 179

Query: 156 LPPREDDSSQSPN-----ACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHES 210
              R +  SQ         C+++G L VNKVAGNFH   GK+      H H   + + +S
Sbjct: 180 EQCRREGFSQKMQEQKNEGCQVYGFLEVNKVAGNFHFAPGKSFQQSHVHVHAVEIHDLQS 239

Query: 211 Y-----NFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPTKLHTYKISA 265
           +     N +H I HLSFGE  P I+NPLD T   A   + MFQYF+ VVPT     K+  
Sbjct: 240 FGLDNINMTHYIQHLSFGEDYPGIVNPLDHTNVTAPQASMMFQYFVKVVPTVY--MKVDG 297

Query: 266 D---THQFSVTERERIINHAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIV 322
           +   T+QFSVT  E++ N   G  G+ G+F+ Y+LS +MV +TE+H  F  F   +C I+
Sbjct: 298 EVLRTNQFSVTRHEKVANGLLGDQGLPGVFVLYELSPMMVKLTEKHRSFTHFLTGVCAII 357

Query: 323 GGIFSTTGMLHGI 335
           GG+F+  G++  +
Sbjct: 358 GGMFTVAGLIDSL 370


>gi|72534712 endoplasmic reticulum-golgi intermediate compartment 32
           kDa protein [Homo sapiens]
          Length = 290

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 25/172 (14%)

Query: 170 CRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHESYNFSHRIDHLSFGEL---- 225
           CR  G   +NKV GNFH++   A   P            ++ + +H I  LSFG+     
Sbjct: 115 CRFEGQFSINKVPGNFHVSTHSATAQP------------QNPDMTHVIHKLSFGDTLQVQ 162

Query: 226 -VPAIINPLDGTEKIAIDHNQMFQYFITVVPTKLHTYKISAD----THQFSVTERERIIN 280
            +    N L G +++  +      Y + +VPT    Y+  +     ++Q++V  +E +  
Sbjct: 163 NIHGAFNALGGADRLTSNPLASHDYILKIVPT---VYEDKSGKQRYSYQYTVANKEYVAY 219

Query: 281 HAAGSHGVSGIFMKYDLSSLMVTVTEEHMPFWQFFVRLCGIVGGIFSTTGML 332
              G   +  I+ +YDLS + V  TE   P ++F   +C I+GG F+  G+L
Sbjct: 220 SHTGRI-IPAIWFRYDLSPITVKYTERRQPLYRFITTICAIIGGTFTVAGIL 270


>gi|31377468 dedicator of cytokinesis 2 [Homo sapiens]
          Length = 1830

 Score = 33.1 bits (74), Expect = 0.42
 Identities = 40/163 (24%), Positives = 67/163 (41%), Gaps = 19/163 (11%)

Query: 22  VPESYVETSASGGTVSLIAFTTMALLTIMEFSVYQDTWMKYEYEVDKDFS---SKLRINI 78
           V ++Y++TS+ G     I  T  AL  + +F V   T     YE  +      S  R+  
Sbjct: 716 VLKTYLDTSSRGEQCEPILRTLKALEYVFKFIVRSRTLFSQLYEGKEQMEFEESMRRLFE 775

Query: 79  DITVAMKCQYVGADVLDLAET-----------MVASA---DGLVYE--PTVFDLSPQQKE 122
            I   MK QY    +L +A             MV  A     L+YE    +  +  Q+++
Sbjct: 776 SINNLMKSQYKTTILLQVAALKYIPSVLHDVEMVFDAKLLSQLLYEFYTCIPPVKLQKQK 835

Query: 123 WQRMLQLIQSRLQEEHSLQDVIFKSAFKSTSTALPPREDDSSQ 165
            Q M +++QS L ++   +D++     K     L  ++D   Q
Sbjct: 836 VQSMNEIVQSNLFKKQECRDILLPVITKELKELLEQKDDMQHQ 878


>gi|4501913 ADAM metallopeptidase domain 23 preproprotein [Homo
           sapiens]
          Length = 832

 Score = 30.0 bits (66), Expect = 3.6
 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 16/110 (14%)

Query: 199 HAHLAALVNHESYNFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPTKL 258
           +  L  + +H++Y   HR  H        +++N +D   K  ++        + +V  + 
Sbjct: 300 YLELMIVNDHKTYK-KHRSSHAHTNNFAKSVVNLVDSIYKEQLNTR------VVLVAVET 352

Query: 259 HTYKISADT--------HQFSVTERERIINHAAGSHGVSGIFMKYDLSSL 300
            T K   D         H+FS   R+RI  HA   H +S +   Y  SSL
Sbjct: 353 WTEKDQIDITTNPVQMLHEFS-KYRQRIKQHADAVHLISRVTFHYKRSSL 401


>gi|208609993 methionine sulfoxide reductase A isoform b [Homo
           sapiens]
          Length = 195

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 27/106 (25%), Positives = 46/106 (43%), Gaps = 13/106 (12%)

Query: 151 STSTALPPREDDSSQSPNACRIHGHLYVNKVAGNFHITVGKAIPHPRGHAHLAALVNHES 210
           S   ALP R++   Q+P A +   H+  N+    F      A+    GHA +  +V    
Sbjct: 32  SPQEALPGRKE---QTPVAAK--HHVNGNRTVEPFPEGTQMAVFEKTGHAEVVRVV---- 82

Query: 211 YNFSHRIDHLSFGELVPAIINPLDGTEKIAIDHNQMFQYFITVVPT 256
               ++ +H+SF EL+       D T+ +   ++   QY   + PT
Sbjct: 83  ----YQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPT 124


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,674,857
Number of Sequences: 37866
Number of extensions: 569054
Number of successful extensions: 1254
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1244
Number of HSP's gapped (non-prelim): 9
length of query: 377
length of database: 18,247,518
effective HSP length: 104
effective length of query: 273
effective length of database: 14,309,454
effective search space: 3906480942
effective search space used: 3906480942
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.