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Search of human proteins with 50659080
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|50659080 serpin peptidase inhibitor, clade A, member 3
precursor [Homo sapiens]
(423 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 828 0.0
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 340 1e-93
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 335 4e-92
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 334 8e-92
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 332 5e-91
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 328 4e-90
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 328 4e-90
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 328 4e-90
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 328 4e-90
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 322 3e-88
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 314 8e-86
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 270 2e-72
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 211 1e-54
gi|13489087 serine (or cysteine) proteinase inhibitor, clade B (... 207 1e-53
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 207 1e-53
gi|110225349 serine (or cysteine) proteinase inhibitor, clade A ... 206 3e-53
gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member... 202 4e-52
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 202 5e-52
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 202 5e-52
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 187 1e-47
gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo s... 185 8e-47
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 185 8e-47
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 184 2e-46
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 828 bits (2140), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSL 60
MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSL
Sbjct: 1 MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSL 60
Query: 61 YKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQ 120
YKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQ
Sbjct: 61 YKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQ 120
Query: 121 HLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI 180
HLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI
Sbjct: 121 HLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI 180
Query: 181 NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVM 240
NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVM
Sbjct: 181 NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVM 240
Query: 241 VPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWR 300
VPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWR
Sbjct: 241 VPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWR 300
Query: 301 DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHK 360
DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHK
Sbjct: 301 DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHK 360
Query: 361 AVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
AVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP
Sbjct: 361 AVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
Query: 421 KQA 423
KQA
Sbjct: 421 KQA 423
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 340 bits (873), Expect = 1e-93
Identities = 189/413 (45%), Positives = 260/413 (62%), Gaps = 5/413 (1%)
Query: 12 LLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDK 71
L A G C + C SP + + + + S N DFAF LY++LVL+ P +
Sbjct: 27 LFAVGLCAPIYCV--SPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ 84
Query: 72 NVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSD 131
N+ FSP+S+ST+LA LSLGAH+ T T+IL+GL FNLT T E+ IHQ FQHL+ +L S
Sbjct: 85 NIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHSLTVPSK 144
Query: 132 ELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGK 191
+L L MG+A+FVK++L L F + KRLY +E F+TDF + + A+ IN +VK T+GK
Sbjct: 145 DLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGK 204
Query: 192 ITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQS-RFYLSKKKWVMVPMMSLHHLT 250
+ D+I+ LD T MVLVN+IFFKAKWE PF P+ T ++ F + ++ V VPMM
Sbjct: 205 VVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKE-Q 263
Query: 251 IPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGE 310
+ D EL+C V+++ Y G+A A F+LP + KM ++E L TL++W SL+ R I E
Sbjct: 264 FAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI-E 322
Query: 311 LYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGT 370
+++P+FSIS YNL IL ++GI+ F AD SGI +L VS+ HKAVLDV EEGT
Sbjct: 323 VFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGT 382
Query: 371 EASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA 423
EA+AAT K + S + V FNR FLM+I T I F+ KV NP ++
Sbjct: 383 EATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS 435
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 335 bits (860), Expect = 4e-92
Identities = 181/373 (48%), Positives = 240/373 (64%), Gaps = 6/373 (1%)
Query: 48 GLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNL 107
GLASANVDFAFSLYK LV +P KN+ SP+SIS ALA LSLG T ++L+GL FNL
Sbjct: 38 GLASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNL 97
Query: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
TE SE EIHQ FQHL + +S L+++MGNA+F+ L LL+ F+ D K Y SE A
Sbjct: 98 TERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLA 157
Query: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
+FQD A A + IN YVKN T+GKI DL LDS ++VLVNYIFFK W PFD T
Sbjct: 158 MNFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTR 217
Query: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEV 287
+ FY+ + V VPMM L TI Y D EL C +V++ Y GN + FILPD+ KM V
Sbjct: 218 EENFYVDETTVVKVPMM-LQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTV 276
Query: 288 EAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGIT 347
A L +T+ RW L ++ +LY+PK +IS Y+L D+L ++GI + FT++A+ S IT
Sbjct: 277 IAALSRDTINRWSAGLTSSQV-DLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRIT 335
Query: 348 GARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTD 407
L S+VVHKAVL + EEG + + +T V + L S + I+RFN+PF+++I
Sbjct: 336 QDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPI----ILRFNQPFIIMIFDHF 391
Query: 408 TQNIFFMSKVTNP 420
T + F+++V NP
Sbjct: 392 TWSSLFLARVMNP 404
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 334 bits (857), Expect = 8e-92
Identities = 186/378 (49%), Positives = 247/378 (65%), Gaps = 7/378 (1%)
Query: 44 HVDLGLA-SANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKG 102
HV +A S+ DF F LY+ L AP +++ FSP+SIS +LA LSLGA ++T +IL+G
Sbjct: 35 HVGATVAPSSRRDFTFDLYRALASAAPSQSIFFSPVSISMSLAMLSLGAGSSTKMQILEG 94
Query: 103 LKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYG 162
L NL ++SE E+H+ FQ LL+ LNQ D QLS+GNA+F + L D F K LY
Sbjct: 95 LGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYL 154
Query: 163 SEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFD 222
++ F T+F+DSA A K INDYV T+GKI DL+K+LDS ++++VNYIFFKAKWE F+
Sbjct: 155 ADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFN 214
Query: 223 PQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQD 282
+ T + FY++ + V VPMMS Y D LSC VV + Y GNA+ALFILP +
Sbjct: 215 HKGTQEQDFYVTSETVVRVPMMSRED-QYHYLLDRNLSCRVVGVPYQGNATALFILPSEG 273
Query: 283 KMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKAD 342
KM++VE L +TL++W + R++ ELYLPKFSI Y L +L LGI FTS AD
Sbjct: 274 KMQQVENGLSEKTLRKWLKMFKKRQL-ELYLPKFSIEGSYQLEKVLPSLGISNVFTSHAD 332
Query: 343 LSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMI 402
LSGI+ N+ VS++VHKAV++V E GT A+AAT T SA + ++ +V FNRPFLM
Sbjct: 333 LSGISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLV-FNRPFLMF 391
Query: 403 IVPTDTQNIFFMSKVTNP 420
IV NI F+ KV P
Sbjct: 392 IV---DNNILFLGKVNRP 406
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 332 bits (850), Expect = 5e-91
Identities = 188/419 (44%), Positives = 249/419 (59%), Gaps = 4/419 (0%)
Query: 5 LPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQL 64
L LL +GLLA + H + Q + L +A AN DFAF Y +
Sbjct: 7 LLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLI 66
Query: 65 VLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLR 124
+ P KN+ FSPLSIS A A LSLGA + + ++IL+GL FNLTE SE+++H+ FQHLL
Sbjct: 67 ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLH 126
Query: 125 TLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYV 184
TLN L+ +G+A+F+ L L +F D +Y ++ F T+F D+ +LIND+V
Sbjct: 127 TLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHV 186
Query: 185 KNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMM 244
K TRGKI DL+ +L +MVLVNYI+FKA WE PF T FY+ + V VPMM
Sbjct: 187 KKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMM 246
Query: 245 SLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLE 304
Y D L C+V+ + Y G+A+ FILP+Q KM E+E +L PE L RW + L
Sbjct: 247 LQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLR 306
Query: 305 FREIG---ELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKA 361
R EL+LPKFSIS Y L+ IL +LG + F+ ADLSGIT + L S+ HKA
Sbjct: 307 KRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKA 366
Query: 362 VLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
LDV E GTEA+AAT+ I SA R I+RFNRPFL++I T TQ++ F+ KV +P
Sbjct: 367 TLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 328 bits (842), Expect = 4e-90
Identities = 187/416 (44%), Positives = 262/416 (62%), Gaps = 13/416 (3%)
Query: 12 LLAAGFC---PAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANV-DFAFSLYKQLVLK 67
LL AG C P L D T + H + N+ +FAFSLY+QL +
Sbjct: 10 LLLAGLCCLVPVSLAEDPQG-DAAQKTDTSHHDQDHPTFNKITPNLAEFAFSLYRQLAHQ 68
Query: 68 APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLN 127
+ N+ FSP+SI+TA A LSLG T EIL+GL FNLTE EA+IH+ FQ LLRTLN
Sbjct: 69 SNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEGFQELLRTLN 128
Query: 128 QSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNG 187
Q +LQL+ GN +F+ E L L+D+F ED K+LY SEAF +F D+ AKK INDYV+ G
Sbjct: 129 QPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKKQINDYVEKG 188
Query: 188 TRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMS-L 246
T+GKI DL+K+LD T+ LVNYIFFK KWE PF+ +DT + F++ + V VPMM L
Sbjct: 189 TQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKVPMMKRL 248
Query: 247 HHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEFR 306
I + + +LS V+ +KY GNA+A+F LPD+ K++ +E L + + ++ ++ E R
Sbjct: 249 GMFNIQHCK--KLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITKFLEN-EDR 305
Query: 307 EIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVF 366
L+LPK SI+ Y+L +L QLGI + F++ ADLSG+T L +S+ VHKAVL +
Sbjct: 306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSKAVHKAVLTID 365
Query: 367 EEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQ 422
E+GTEA+ A ++ +S E V+FN+PF+ +++ +T++ FM KV NP Q
Sbjct: 366 EKGTEAAGAMFLEAIPMSIPPE----VKFNKPFVFLMIEQNTKSPLFMGKVVNPTQ 417
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 322 bits (826), Expect = 3e-88
Identities = 182/423 (43%), Positives = 261/423 (61%), Gaps = 11/423 (2%)
Query: 4 MLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQ 63
M P L L LL G + C SP + +Q T + +S N DFAF+LY++
Sbjct: 1 MSPFLYLVLLVLGLHATIHCA--SPEGKVTACHSSQPNATLYKM--SSINADFAFNLYRR 56
Query: 64 LVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLL 123
++ PDKN+ FSP+SIS AL LS GA +T TEI++ L FNLT+T EI FQHL+
Sbjct: 57 FTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPMVEIQHGFQHLI 116
Query: 124 RTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDY 183
+LN EL+L +GNA+F+ + L L +F D K LY +E F+TDF + +AAK+ IN +
Sbjct: 117 CSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSNISAAKQEINSH 176
Query: 184 VKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH-QSRFYLSKKKWVMVP 242
V+ T+GK+ LI+DL T+MVLVNYI FKA+W PFDP T S F + K V VP
Sbjct: 177 VEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSFLIDKTTTVQVP 236
Query: 243 MMSLHHLTIPYFR--DEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWR 300
MM H Y+ D EL+CTV+++ Y+ NA ALF+LP + +ME VEA + +TLK+W
Sbjct: 237 MM---HQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMSSKTLKKWN 293
Query: 301 DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHK 360
L+ + +L++PKFSIS Y+L LL++GI+ A++ AD SG+T L +S HK
Sbjct: 294 RLLQKGWV-DLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHK 352
Query: 361 AVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
AVL + E+GTEA+A V+++ I++ +R F+++I+ T++I F+ KV NP
Sbjct: 353 AVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVVNP 412
Query: 421 KQA 423
+A
Sbjct: 413 TEA 415
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 314 bits (805), Expect = 8e-86
Identities = 172/415 (41%), Positives = 249/415 (60%), Gaps = 4/415 (0%)
Query: 7 LLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVL 66
LL G+LA+ C +L H + L + + +FA LYK+L
Sbjct: 8 LLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAA 67
Query: 67 KAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTL 126
AP N+ FSP+SIST LA LSLGA T IL+GL FNLTET EA+IHQ F+ LL TL
Sbjct: 68 DAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEADIHQGFRSLLHTL 126
Query: 127 NQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKN 186
S +L+L +GN++F+ ++L + + K LYG+ AF+ +F DS + INDY++
Sbjct: 127 ALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRR 186
Query: 187 GTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH-QSRFYLSKKKWVMVPMMS 245
T G++ D + + T MVL NYIFFKAKW+ PF T Q F++ ++ + VPMM
Sbjct: 187 QTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMH 246
Query: 246 LHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEVEAMLLPETLKRWRDSLEF 305
+ + D++L+CTV++++Y GNA AL +LPD KM++VEA L P+TL++W L
Sbjct: 247 QKEMH-RFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQTLRKW-GQLLL 304
Query: 306 REIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDV 365
+ +L+LP+FSIS YNL DIL Q+G+ +AD SG+TG N +S+V HKA++D+
Sbjct: 305 PSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTISKVSHKAMVDM 364
Query: 366 FEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
E+GTEA AA+ + S + FNRPFL+++ TQ++ F+ KV NP
Sbjct: 365 SEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNP 419
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 270 bits (690), Expect = 2e-72
Identities = 140/373 (37%), Positives = 227/373 (60%), Gaps = 10/373 (2%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
LA N+D F L K+L P +N+ SPLSISTA + L LGA ++TL EI +G FN
Sbjct: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFR 105
Query: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
+ E ++H+ F +++ L Q + +L+LS+GN +F+ ++L +F EDAK Y +E T
Sbjct: 106 KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILT 165
Query: 169 DFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQ 228
+FQ+ A+K IND++ T GKI +LI+++D T+M+L NYIFF+A+W+ FDP T +
Sbjct: 166 NFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE 225
Query: 229 SRFYLSKKKWVMVPMMSLHHL-TIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEV 287
F+L K V VPMM + + Y D++LSCT++E+ Y N +A+FILPD+ K++ +
Sbjct: 226 EDFFLEKNSSVKVPMMFRSGIYQVGY--DDKLSCTILEIPYQKNITAIFILPDEGKLKHL 283
Query: 288 EAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGIT 347
E L +T RW+ L R + ++ +P+ ++ ++L L +G+ + F DL+ I
Sbjct: 284 EKGLQVDTFSRWKTLLS-RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIA 342
Query: 348 GARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTD 407
R+L V + VHKA L + E GTE +A T + + +ET +V+ ++P+L++I
Sbjct: 343 PHRSLKVGEAVHKAELKMDERGTEGAAGTGAQ----TLPMETPLVVKIDKPYLLLIYSEK 398
Query: 408 TQNIFFMSKVTNP 420
++ F+ K+ NP
Sbjct: 399 IPSVLFLGKIVNP 411
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 211 bits (537), Expect = 1e-54
Identities = 130/390 (33%), Positives = 218/390 (55%), Gaps = 21/390 (5%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-L 107
L+ AN F F L++Q K+ + N+ +SP+SI++AL + LGA + T +I K L F+ +
Sbjct: 4 LSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQV 62
Query: 108 TETSEAE-----------IHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTED 156
TE + + +H FQ LL N+S+D +L + N +F ++ L + +
Sbjct: 63 TENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDA 122
Query: 157 AKRLYGSEAFATDFQDSAA-AKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYIFF 213
K+ Y + + DF ++ ++K IN +V++ T KI +LI + + S T +VLVN I+F
Sbjct: 123 IKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYF 182
Query: 214 KAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTG-NA 272
K +WE F+ +DT + +F+ +K + + MM + + + E++ V+E+ Y G +
Sbjct: 183 KGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMR-QYTSFHFASLEDVQAKVLEIPYKGKDL 241
Query: 273 SALFILPDQ-DKMEEVEAMLLPETLKRWRDSLEFREIG-ELYLPKFSISRDYNLNDILLQ 330
S + +LP++ D ++++E L E L W RE +L+LP+F + Y+L D L
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRT 301
Query: 331 LGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETR 390
+G+ + F ADLSG+TG+R L +S V+HKA ++V EEG EA+AATAV + S+ T
Sbjct: 302 MGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAV-VGFGSSPTSTN 360
Query: 391 TIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
N PFL I T +I F + ++P
Sbjct: 361 EEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|13489087 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 1 [Homo sapiens]
Length = 379
Score = 207 bits (528), Expect = 1e-53
Identities = 134/384 (34%), Positives = 210/384 (54%), Gaps = 20/384 (5%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
L+SAN FA L+ L P N+ SP SIS+A+A + LG T ++ K FN
Sbjct: 4 LSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNTV 63
Query: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
E E+H FQ L +N+ L + N ++ ++ + L F ++ YG++ +
Sbjct: 64 E----EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLASV 119
Query: 169 DFQDSAA-AKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYIFFKAKWEMPFDPQD 225
DFQ ++ A+K IN +VK T GKI +L+ +D+ T +VLVN I+FK W+ F +
Sbjct: 120 DFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKEA 179
Query: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA-SALFILPDQDK- 283
T + F L+KK V MM Y E+L C V+EL Y G S + +LPD +
Sbjct: 180 TTNAPFRLNKKDRKTVKMM-YQKKKFAYGYIEDLKCRVLELPYQGEELSMVILLPDDIED 238
Query: 284 ----MEEVEAMLLPETLKRWR--DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAF 337
++++E L E L W ++L+F E+ + LP+F + Y LN L +LG+++ F
Sbjct: 239 ESTGLKKIEEQLTLEKLHEWTKPENLDFIEVN-VSLPRFKLEESYTLNSDLARLGVQDLF 297
Query: 338 -TSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFN 396
+SKADLSG++GAR++ +S++VHK+ ++V EEGTEA+AATA T + E +
Sbjct: 298 NSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMLMPEENFTA--D 355
Query: 397 RPFLMIIVPTDTQNIFFMSKVTNP 420
PFL I + +I F+ + ++P
Sbjct: 356 HPFLFFIRHNSSGSILFLGRFSSP 379
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 207 bits (527), Expect = 1e-53
Identities = 131/390 (33%), Positives = 216/390 (55%), Gaps = 21/390 (5%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKF--- 105
L+ AN F F L++Q K+ + N+ +SP+SI++AL + LGA + T +I K L F
Sbjct: 4 LSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQV 62
Query: 106 --NLTETS-------EAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTED 156
N TE + +H FQ LL N+S+D +L + N +F ++ L + +
Sbjct: 63 TENTTEKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDA 122
Query: 157 AKRLYGSEAFATDFQDSAA-AKKLINDYVKNGTRGKITDLIKD--LDSQTMMVLVNYIFF 213
K+ Y + +TDF ++ ++K IN +V++ T KI +L D + + T +VLVN I+F
Sbjct: 123 IKKFYQTSVESTDFANAPEESRKKINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYF 182
Query: 214 KAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTG-NA 272
K +WE F ++T + +F+ +K + V MM ++ + + E++ V+E+ Y G +
Sbjct: 183 KGQWENKFKKENTKEEKFWPNKNTYKSVQMMRQYN-SFNFALLEDVQAKVLEIPYKGKDL 241
Query: 273 SALFILPDQ-DKMEEVEAMLLPETLKRWRDSLEFREIG-ELYLPKFSISRDYNLNDILLQ 330
S + +LP++ D ++++E L E L W RE +L+LP+F + Y+L D L
Sbjct: 242 SMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRT 301
Query: 331 LGIEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETR 390
+G+ F ADLSG+T + L+VS+V+HKA ++V EEG EA+AATAV + LS+ T
Sbjct: 302 MGMVNIFNGDADLSGMTWSHGLSVSKVLHKAFVEVTEEGVEAAAATAVVVVELSS-PSTN 360
Query: 391 TIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
N PFL I T +I F + ++P
Sbjct: 361 EEFCCNHPFLFFIRQNKTNSILFYGRFSSP 390
>gi|110225349 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
B [Homo sapiens]
Length = 335
Score = 206 bits (524), Expect = 3e-53
Identities = 120/271 (44%), Positives = 164/271 (60%), Gaps = 3/271 (1%)
Query: 154 TEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFF 213
T+ A RLY T Q+ + IN +VK T+GK+ D+I+ LD T MVLVN+IFF
Sbjct: 67 TDFAFRLYRRLVLETPSQNIFFSPARINSHVKKKTQGKVVDIIQGLDLLTAMVLVNHIFF 126
Query: 214 KAKWEMPFDPQDTHQS-RFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNA 272
KAKWE PF P+ T ++ F + ++ V VPMM + D EL+C V+++ Y G+A
Sbjct: 127 KAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKE-QFAFGVDTELNCFVLQMDYKGDA 185
Query: 273 SALFILPDQDKMEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLG 332
A F+LP + KM ++E L TL++W SL+ R I E+++P+FSIS YNL IL ++G
Sbjct: 186 VAFFVLPSKGKMRQLEQALSARTLRKWSHSLQKRWI-EVFIPRFSISASYNLETILPKMG 244
Query: 333 IEEAFTSKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTI 392
I+ F AD SGI +L VS+ HKAVLDV EEGTEA+AAT K + S +
Sbjct: 245 IQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFT 304
Query: 393 VRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA 423
V FNR FLM+I T I F+ KV NP ++
Sbjct: 305 VSFNRTFLMMITNKATDGILFLGKVENPTKS 335
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 6/92 (6%)
Query: 12 LLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDK 71
L A G C + C SP + + + + S N DFAF LY++LVL+ P +
Sbjct: 27 LFAVGLCAPIYCV--SPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLVLETPSQ 84
Query: 72 NVIFSPLSISTALAFLSLGAHNTTLTEILKGL 103
N+ FSP I++ + + G + +I++GL
Sbjct: 85 NIFFSPARINSHVKKKTQG----KVVDIIQGL 112
>gi|5453886 serpin peptidase inhibitor, clade I (pancpin), member 2
[Homo sapiens]
Length = 405
Score = 202 bits (515), Expect = 4e-52
Identities = 121/376 (32%), Positives = 202/376 (53%), Gaps = 11/376 (2%)
Query: 50 ASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTE 109
A N +FA LY+++ L D N+IFSPL I+ L + LGA +I + LK E
Sbjct: 23 AQKNTEFAVDLYQEVSLSHKD-NIIFSPLGITLVLEMVQLGAKGKAQQQIRQTLKQQ--E 79
Query: 110 TSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATD 169
TS E + +++ E ++ NA++++E ++ +++ K + S D
Sbjct: 80 TSAGEEFFVLKSFFSAISEKKQEFTFNLANALYLQEGFTVKEQYLHGNKEFFQSAIKLVD 139
Query: 170 FQDSAAAKKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
FQD+ A ++I+ +V+ T GKI D+ ++ T +VLVN I+FK W+ F +DT
Sbjct: 140 FQDAKACAEMISTWVERKTDGKIKDMFSGEEFGPLTRLVLVNAIYFKGDWKQKFRKEDTQ 199
Query: 228 QSRFYLSKKKWVMVPMM-SLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKM-- 284
F V +PMM +L YF + L+ V+EL Y G+ +L I+ + M
Sbjct: 200 LINFTKKNGSTVKIPMMKALLRTKYGYFSESSLNYQVLELSYKGDEFSLIIILPAEGMDI 259
Query: 285 EEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLS 344
EEVE ++ + + +W ++ E+ E+ LP+F + + + D+L L I E F+ DLS
Sbjct: 260 EEVEKLITAQQILKWLSEMQEEEV-EISLPRFKVEQKVDFKDVLYSLNITEIFSGGCDLS 318
Query: 345 GITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIV 404
GIT + + VSQV K ++ E+G+EA+ +T + I ++ +L +++ I N PFL I+
Sbjct: 319 GITDSSEVYVSQVTQKVFFEINEDGSEAATSTGIHIPVIMSLAQSQFIA--NHPFLFIMK 376
Query: 405 PTDTQNIFFMSKVTNP 420
T++I FM +VTNP
Sbjct: 377 HNPTESILFMGRVTNP 392
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 202 bits (514), Expect = 5e-52
Identities = 127/377 (33%), Positives = 212/377 (56%), Gaps = 15/377 (3%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-L 107
LA +F FSL +++ ++ D N++FSP +S A+ L LGA T T+I +GL L
Sbjct: 75 LAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
Query: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
T + F+ L TL+++ EL L+ G+ F+ + + + F +KR + +E
Sbjct: 134 KPTKPGLLPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
Query: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
+F++++ AK+L+N Y+ TRGKI L +++ +T ++LV+YI FK KW PFDP T
Sbjct: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
Query: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEE- 286
F+L K K + VPMM F D+ C V++L Y GNA+ L +L +KM +
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVL--MEKMGDH 309
Query: 287 --VEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLS 344
+E L + ++ W +++ R + E++ PKF + + Y ++++L Q+GI F+ ADLS
Sbjct: 310 LALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368
Query: 345 GITG-ARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMII 403
++ RNL VS+V+ + V++V E GTEA A +IT S +++ +RPF +I
Sbjct: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS----MPPVIKVDRPFHFMI 424
Query: 404 VPTDTQNIFFMSKVTNP 420
+ + F+ +V NP
Sbjct: 425 YEETSGMLLFLGRVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 202 bits (514), Expect = 5e-52
Identities = 127/377 (33%), Positives = 212/377 (56%), Gaps = 15/377 (3%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFN-L 107
LA +F FSL +++ ++ D N++FSP +S A+ L LGA T T+I +GL L
Sbjct: 75 LAKETSNFGFSLLRKISMRH-DGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQAL 133
Query: 108 TETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFA 167
T + F+ L TL+++ EL L+ G+ F+ + + + F +KR + +E
Sbjct: 134 KPTKPGLLPSLFKGLRETLSRNL-ELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVP 192
Query: 168 TDFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTH 227
+F++++ AK+L+N Y+ TRGKI L +++ +T ++LV+YI FK KW PFDP T
Sbjct: 193 MNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTE 252
Query: 228 QSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEE- 286
F+L K K + VPMM F D+ C V++L Y GNA+ L +L +KM +
Sbjct: 253 VDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVL--MEKMGDH 309
Query: 287 --VEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLS 344
+E L + ++ W +++ R + E++ PKF + + Y ++++L Q+GI F+ ADLS
Sbjct: 310 LALEDYLTTDLVETWLRNMKTRNM-EVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLS 368
Query: 345 GITG-ARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMII 403
++ RNL VS+V+ + V++V E GTEA A +IT S +++ +RPF +I
Sbjct: 369 ELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYS----MPPVIKVDRPFHFMI 424
Query: 404 VPTDTQNIFFMSKVTNP 420
+ + F+ +V NP
Sbjct: 425 YEETSGMLLFLGRVVNP 441
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 187 bits (476), Expect = 1e-47
Identities = 130/380 (34%), Positives = 203/380 (53%), Gaps = 15/380 (3%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
L++A+ FA L K L P NV SP+SIS+ALA + LGA T T++ + L N
Sbjct: 4 LSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLN-- 61
Query: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
+E +IH++FQ LL +N++ + L N +F ++ L F E + Y +E
Sbjct: 62 --TEEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKEL 119
Query: 169 DFQDSA-AAKKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWEMPFDPQD 225
F +A ++K IN +V T GKI +L+ +D++T +VLVN I+FK KW PFD
Sbjct: 120 SFIRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETY 179
Query: 226 THQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYT-GNASALFILPDQD-K 283
T + F +++++ V MM T E+ ++EL Y S L +LPD +
Sbjct: 180 TREMPFKINQEEQRPVQMM-YQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVE 238
Query: 284 MEEVEAMLLPETLKRWR--DSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAF-TSK 340
+ VE L E L W D ++ E+ E+ LPKF + DY++ +L LGI +AF K
Sbjct: 239 LSTVEKSLTFEKLTAWTKPDCMKSTEV-EVLLPKFKLQEDYDMESVLRHLGIVDAFQQGK 297
Query: 341 ADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFL 400
ADLS ++ R+L +S+ VHK+ ++V EEGTEA+AA++ + +E+ + PFL
Sbjct: 298 ADLSAMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSC-FVVAECCMESGPRFCADHPFL 356
Query: 401 MIIVPTDTQNIFFMSKVTNP 420
I +I F + ++P
Sbjct: 357 FFIRHNRANSILFCGRFSSP 376
>gi|4502261 serpin peptidase inhibitor, clade C, member 1 [Homo
sapiens]
Length = 464
Score = 185 bits (469), Expect = 8e-47
Identities = 145/447 (32%), Positives = 230/447 (51%), Gaps = 40/447 (8%)
Query: 10 LGLLAAGFCPAVLCH--------------PNSPL-----------DEENLTQENQDRGTH 44
L LL GF V CH P +P+ ++E Q+ +
Sbjct: 19 LSLLLIGFWDCVTCHGSPVDICTAKPRDIPMNPMCIYRSPEKKATEDEGSEQKIPEATNR 78
Query: 45 VDLGLASANVDFAFSLYKQLV-LKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGL 103
L+ AN FA + Y+ L K + N+ SPLSISTA A LGA N TL ++++
Sbjct: 79 RVWELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVF 138
Query: 104 KFN-LTETSEAEIHQSFQHL-LRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLY 161
KF+ ++E + +IH F L R +++ +L N +F + L+ + + + ++ +Y
Sbjct: 139 KFDTISEKTSDQIHFFFAKLNCRLYRKANKSSKLVSANRLFGDKSLTFNETYQDISELVY 198
Query: 162 GSEAFATDFQDSA-AAKKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIFFKAKWE 218
G++ DF+++A ++ IN +V N T G+ITD+I + ++ T++VLVN I+FK W+
Sbjct: 199 GAKLQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINELTVLVLVNTIYFKGLWK 258
Query: 219 MPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTG-NASALFI 277
F P++T + FY + + MM Y R E V+EL + G + + + I
Sbjct: 259 SKFSPENTRKELFYKADGESCSASMM-YQEGKFRYRRVAE-GTQVLELPFKGDDITMVLI 316
Query: 278 LPDQDK-MEEVEAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEA 336
LP +K + +VE L PE L+ W D LE + +++P+F I ++L + L +G+ +
Sbjct: 317 LPKPEKSLAKVEKELTPEVLQEWLDELEEMML-VVHMPRFRIEDGFSLKEQLQDMGLVDL 375
Query: 337 FT-SKADLSGIT--GARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIV 393
F+ K+ L GI G +L VS HKA L+V EEG+EA+A+TAV I S L R
Sbjct: 376 FSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGRS-LNPNRVTF 434
Query: 394 RFNRPFLMIIVPTDTQNIFFMSKVTNP 420
+ NRPFL+ I I FM +V NP
Sbjct: 435 KANRPFLVFIREVPLNTIIFMGRVANP 461
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 185 bits (469), Expect = 8e-47
Identities = 127/398 (31%), Positives = 209/398 (52%), Gaps = 30/398 (7%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
LA++ FA L K+L A KN+ FS SIST+L + LGA TT ++ + L+FN
Sbjct: 4 LATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63
Query: 109 E------------------TSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLL 150
+ ++ EIH FQ L+ + + +D+ L NA++ ++ +
Sbjct: 64 QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFH 123
Query: 151 DRFTEDAKRLYGSEAFATDFQDSA-AAKKLINDYVKNGTRGKITDLIKD--LDSQTMMVL 207
+++ ED K +G+E +F +++ +K IN +V+ T GKI +L+ D +DS T M+L
Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183
Query: 208 VNYIFFKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELK 267
VN ++FK WE F Q+T + F +++ V MM + + F E+ ++L
Sbjct: 184 VNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKK-KLHIFHIEKPKAVGLQLY 242
Query: 268 YTGNASALFILPDQD--KMEEVEAMLLPETLKRWR--DSLEFREIGELYLPKFSISRDYN 323
Y +L IL +D +E++E + E L W D +E E+ +L+LPKF + Y+
Sbjct: 243 YKSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEV-QLHLPKFKLEDSYD 301
Query: 324 LNDILLQLGIEEAFT-SKADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITL 382
L L +G+ +AF+ SKAD SG++ ARNL +S V HKA +++ E+GTEA+A + +I +
Sbjct: 302 LKSTLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDI 361
Query: 383 LSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
+ N PFL I T I F ++ +P
Sbjct: 362 RIRVPSIE--FNANHPFLFFIRHNKTNTILFYGRLCSP 397
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 184 bits (466), Expect = 2e-46
Identities = 126/394 (31%), Positives = 203/394 (51%), Gaps = 27/394 (6%)
Query: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
L++ANV+F ++K+L N+ FS LS+ AL+ + LGA T ++ K L F+ T
Sbjct: 4 LSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHT 63
Query: 109 ETS-------------EAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTE 155
S IH F +NQ LS+ N ++ + ++ ++
Sbjct: 64 VDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLS 123
Query: 156 DAKRLYGSEAFATDFQDSAA-AKKLINDYVKNGTRGKITDLI--KDLDSQTMMVLVNYIF 212
+++ Y + DF+ S +K IN +V+N T GK+ +L +D ++MVLVN I+
Sbjct: 124 CSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIY 183
Query: 213 FKAKWEMPFDPQDTHQSRFYLSKKKWVMVPMM-SLHHLTIPYFRDEELSCTVVELKYTGN 271
FK +W+ F ++T +S F LS+ K V V MM + + + ++ ++ V+EL Y N
Sbjct: 184 FKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQ--VLELPYVNN 241
Query: 272 ASALFILPDQD--KMEEVEAMLLPETLKRWRDSLEF--REIGELYLPKFSISRDYNLNDI 327
++ IL ++++E L T W S RE+ E++LP+F + Y LN +
Sbjct: 242 KLSMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREV-EVHLPRFKLETKYELNSL 300
Query: 328 LLQLGIEEAFTS-KADLSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSAL 386
L LG+ + F KADLSG++ + L +S+ +HK+ LDV EEGTEA+AAT I + S
Sbjct: 301 LKSLGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKS-- 358
Query: 387 VETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNP 420
+ R + N PFL I T T I F K+ +P
Sbjct: 359 LPMRAQFKANHPFLFFIRHTHTNTILFCGKLASP 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,650,589
Number of Sequences: 37866
Number of extensions: 544214
Number of successful extensions: 1662
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1391
Number of HSP's gapped (non-prelim): 72
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.