Search of human proteins with 5031719

Search of human proteins with 5031719

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5031719 glypican 6 precursor [Homo sapiens]
         (555 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5031719 glypican 6 precursor [Homo sapiens]                       1130   0.0  
gi|21614525 glypican 4 [Homo sapiens]                                 722   0.0  
gi|167001141 glypican 1 precursor [Homo sapiens]                      515   e-146
gi|22749459 glypican 2 [Homo sapiens]                                 451   e-127
gi|4758464 glypican 5 [Homo sapiens]                                  203   3e-52
gi|4758462 glypican 3 [Homo sapiens]                                  182   7e-46
gi|4502315 ATPase, H+ transporting, lysosomal V1 subunit C1 [Hom...    34   0.31 
gi|30061567 La ribonucleoprotein domain family member 2 isoform ...    33   0.68 
gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]      33   0.68 
gi|45439342 peptidylprolyl isomerase (cyclophilin)-like 5 isofor...    31   3.4  
gi|50345881 cytoplasmic polyadenylation element binding protein ...    30   7.6  
gi|13994250 tektin 3 [Homo sapiens]                                    30   7.6  
gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens]     30   7.6  
gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens]     30   7.6  
gi|223029410 talin 1 [Homo sapiens]                                    29   9.9  
gi|34577055 F-box only protein 30 [Homo sapiens]                       29   9.9  
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]      29   9.9  
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]                29   9.9  

>gi|5031719 glypican 6 precursor [Homo sapiens]
          Length = 555

 Score = 1130 bits (2923), Expect = 0.0
 Identities = 555/555 (100%), Positives = 555/555 (100%)

Query: 1   MPSWIGAVILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC 60
           MPSWIGAVILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC
Sbjct: 1   MPSWIGAVILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC 60

Query: 61  PQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSL 120
           PQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSL
Sbjct: 61  PQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSL 120

Query: 121 NDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQY 180
           NDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQY
Sbjct: 121 NDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQY 180

Query: 181 HFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSP 240
           HFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSP
Sbjct: 181 HFSEDYLECVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSP 240

Query: 241 TPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAE 300
           TPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAE
Sbjct: 241 TPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAE 300

Query: 301 RLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF 360
           RLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF
Sbjct: 301 RLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENF 360

Query: 361 NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE 420
           NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE
Sbjct: 361 NTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEE 420

Query: 421 ECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNG 480
           ECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNG
Sbjct: 421 ECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNG 480

Query: 481 NDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLS 540
           NDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLS
Sbjct: 481 NDVNFQDTSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLS 540

Query: 541 WSLTCIVLALQRLCR 555
           WSLTCIVLALQRLCR
Sbjct: 541 WSLTCIVLALQRLCR 555


>gi|21614525 glypican 4 [Homo sapiens]
          Length = 556

 Score =  722 bits (1864), Expect = 0.0
 Identities = 352/546 (64%), Positives = 433/546 (79%), Gaps = 3/546 (0%)

Query: 9   ILPLLGLLLSLPAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCT 68
           +L  L +L +    A++K++SC EVR+ Y +KGF+  D P  EI G+HL+ICPQ  TCC+
Sbjct: 9   LLCTLAVLSAALLAAELKSKSCSEVRRLYVSKGFNKNDAPLHEINGDHLKICPQGSTCCS 68

Query: 69  TEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTY 128
            EME+K S QSK +F+++V E  + ++  F SR+KKFDEFF+ELLENAEKSLNDMFV+TY
Sbjct: 69  QEMEEKYSLQSKDDFKSVVSEQCNHLQAVFASRYKKFDEFFKELLENAEKSLNDMFVKTY 128

Query: 129 GMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLE 188
           G LYMQNSE+F+DLF ELKRYY  GNVNLEEMLNDFWARLLERMF+L+N QYHF+++YLE
Sbjct: 129 GHLYMQNSELFKDLFVELKRYYVVGNVNLEEMLNDFWARLLERMFRLVNSQYHFTDEYLE 188

Query: 189 CVSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRAL 248
           CVSKYT+QLKPFGDVPRKLK+QVTRAF+AARTF QGL V  +V ++VS V+PT  C  AL
Sbjct: 189 CVSKYTEQLKPFGDVPRKLKLQVTRAFVAARTFAQGLAVAGDVVSKVSVVNPTAQCTHAL 248

Query: 249 MKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNI 308
           +KM+YC +CRGL TV+PC NYC N+M+GCLANQ DLD EWN FIDAML+VAERLEGPFNI
Sbjct: 249 LKMIYCSHCRGLVTVKPCYNYCSNIMRGCLANQGDLDFEWNNFIDAMLMVAERLEGPFNI 308

Query: 309 ESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPEN-FNTRFRPY 367
           ESVMDPIDVKIS+AIMNMQ+NS+QVS KVFQGCG PKP PA R +RS  E+ F+ RFRP+
Sbjct: 309 ESVMDPIDVKISDAIMNMQDNSVQVSQKVFQGCGPPKPLPAGRISRSISESAFSARFRPH 368

Query: 368 NPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHS 427
           +PEERPTTAAGTSLDRLVTD+KEKLK +KK WS+LP  +C DE + AG  NE++CWNG  
Sbjct: 369 HPEERPTTAAGTSLDRLVTDVKEKLKQAKKFWSSLPSNVCNDERMAAGNGNEDDCWNGKG 428

Query: 428 KARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQD 487
           K+RYL  +  +GL NQ NNPEV VD ++PD  I +QIMALRVMT+K+KNAYNGNDV+F D
Sbjct: 429 KSRYLFAVTGNGLANQGNNPEVQVDTSKPDILILRQIMALRVMTSKMKNAYNGNDVDFFD 488

Query: 488 TSDESSGSGSGSGCMDDVCPTEFEFVTTEAPAVDPDRREVDSSAAQRGHSLLSWSLTCIV 547
            SDESSG GSGSGC    CP+EF++  T+      + +  DS+  + G      ++ CI+
Sbjct: 489 ISDESSGEGSGSGCEYQQCPSEFDYNATDHAGKSANEK-ADSAGVRPGAQAYLLTVFCIL 547

Query: 548 -LALQR 552
            L +QR
Sbjct: 548 FLVMQR 553


>gi|167001141 glypican 1 precursor [Homo sapiens]
          Length = 558

 Score =  515 bits (1326), Expect = e-146
 Identities = 241/481 (50%), Positives = 345/481 (71%), Gaps = 9/481 (1%)

Query: 26  KARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRICPQEYTCCTTEMEDKLSQQSKLEFEN 85
           K+RSCGEVRQ YGAKGFSL+D+P  EI+GEHLRICPQ YTCCT+EME+ L+ +S  E E 
Sbjct: 28  KSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENLANRSHAELET 87

Query: 86  LVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTE 145
            + ++S  ++    ++ + FD+ F+ LL ++E++L   F   +G LY QN+  F+DL++E
Sbjct: 88  ALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFPGAFGELYTQNARAFRDLYSE 147

Query: 146 LKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQYHFSEDYLECVSKYTDQLKPFGDVPR 205
           L+ YY G N++LEE L +FWARLLER+F+ ++PQ    +DYL+C+ K  + L+PFG+ PR
Sbjct: 148 LRLYYRGANLHLEETLAEFWARLLERLFKQLHPQLLLPDDYLDCLGKQAEALRPFGEAPR 207

Query: 206 KLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRP 265
           +L+++ TRAF+AAR+FVQGL V  +V  +V++V   P C RA+MK++YC +C G+P  RP
Sbjct: 208 ELRLRATRAFVAARSFVQGLGVASDVVRKVAQVPLGPECSRAVMKLVYCAHCLGVPGARP 267

Query: 266 CNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMN 325
           C +YC NV+KGCLANQADLD EW   +D+M+L+ ++  G   +ESV+  +   ++EAI  
Sbjct: 268 CPDYCRNVLKGCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINA 327

Query: 326 MQENSMQVSAKVFQGCGQPKPAPALRSARSAPENFNTRFRPYNPEERPTTAAGTSLDRLV 385
           +Q+N   ++AKV QGCG PK  P        PE    R +   P ERP +    +L++LV
Sbjct: 328 LQDNRDTLTAKVIQGCGNPKVNP----QGPGPEEKRRRGK-LAPRERPPSG---TLEKLV 379

Query: 386 TDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHSKARYLPEIMNDGLTNQIN 445
           ++ K +L+  +  W +LP T+C  E +   T++++ CWNG ++ RYLPE+M DGL NQIN
Sbjct: 380 SEAKAQLRDVQDFWISLPGTLC-SEKMALSTASDDRCWNGMARGRYLPEVMGDGLANQIN 438

Query: 446 NPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQDTSDESSGSGSGSGCMDDV 505
           NPEV+VDIT+PD  IRQQIM L++MTN+L++AYNGNDV+FQD SD+ SGSGSG GC+DD+
Sbjct: 439 NPEVEVDITKPDMTIRQQIMQLKIMTNRLRSAYNGNDVDFQDASDDGSGSGSGDGCLDDL 498

Query: 506 C 506
           C
Sbjct: 499 C 499


>gi|22749459 glypican 2 [Homo sapiens]
          Length = 579

 Score =  451 bits (1160), Expect = e-127
 Identities = 227/512 (44%), Positives = 329/512 (64%), Gaps = 16/512 (3%)

Query: 7   AVILPLLGLLLSL-------PAGADVKARSCGEVRQAYGAKGFSLADIPYQEIAGEHLRI 59
           + + PLL LLL L       P       RSC E RQ  GA+G+SL  IP   I+GEHLR+
Sbjct: 2   SALRPLLLLLLPLCPGPGPGPGSEAKVTRSCAETRQVLGARGYSLNLIPPALISGEHLRV 61

Query: 60  CPQEYTCCTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKS 119
           CPQEYTCC++E E +L ++++  F  LVE++  F+  T  +RH+KFDEFF E+L  A+ S
Sbjct: 62  CPQEYTCCSSETEQRLIRETEATFRGLVEDSGSFLVHTLAARHRKFDEFFLEMLSVAQHS 121

Query: 120 LNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQLINPQ 179
           L  +F  +YG LY Q++ +F  LF+ L+ +Y      L++ L DFWA+LLER+F L++PQ
Sbjct: 122 LTQLFSHSYGRLYAQHALIFNGLFSRLRDFYGESGEGLDDTLADFWAQLLERVFPLLHPQ 181

Query: 180 YHFSEDYLECVSKYTD----QLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRV 235
           Y F  DYL C+S+        L+PFGD PR+L++Q+TR  +AAR FVQGL  GR V +  
Sbjct: 182 YSFPPDYLLCLSRLASSTDGSLQPFGDSPRRLRLQITRTLVAARAFVQGLETGRNVVSEA 241

Query: 236 SKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAM 295
            KV  + GC +ALM+++ CP CRG+P++ PC  +CLNV++GCL+++  L+ +W  ++D +
Sbjct: 242 LKVPVSEGCSQALMRLIGCPLCRGVPSLMPCQGFCLNVVRGCLSSRG-LEPDWGNYLDGL 300

Query: 296 LLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARS 355
           L++A++L+GPF+ E   + I VKISE +M +QENS +VSA+VFQ CG P P PA R+ R+
Sbjct: 301 LILADKLQGPFSFELTAESIGVKISEGLMYLQENSAKVSAQVFQECGPPDPVPA-RNRRA 359

Query: 356 AP--ENFNTRFRPYNPEERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVT 413
            P  E     +     EERPTTAAGT+L RLV +++E+L   +  W+ L  T+C D  + 
Sbjct: 360 PPPREEAGRLWSMVTEEERPTTAAGTNLHRLVWELRERLARMRGFWARLSLTVCGDSRMA 419

Query: 414 AGTSNE-EECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTN 472
           A  S E   CW G  + RYLP ++      Q+NNPE+ VD + PD   R++ + LR  T 
Sbjct: 420 ADASLEAAPCWTGAGRGRYLPPVVGGSPAEQVNNPELKVDASGPDVPTRRRRLQLRAATA 479

Query: 473 KLKNAYNGNDVNFQDTSDESSGSGSGSGCMDD 504
           ++K A  G+D++ QD  +++SGSG G    DD
Sbjct: 480 RMKTAALGHDLDGQDADEDASGSGGGQQYADD 511


>gi|4758464 glypican 5 [Homo sapiens]
          Length = 572

 Score =  203 bits (517), Expect = 3e-52
 Identities = 139/507 (27%), Positives = 253/507 (49%), Gaps = 31/507 (6%)

Query: 15  LLLSLPAGADVKA-RSCGEVRQAYGAKGF-SLADIPYQEIAGEHLRIC-PQEYTCCTTEM 71
           LLL+L   A  +  ++C EVR+ +  +   ++  +P    AG  L++C  ++ TCCT +M
Sbjct: 14  LLLALVGSARSEGVQTCEEVRKLFQWRLLGAVRGLPDSPRAGPDLQVCISKKPTCCTRKM 73

Query: 72  EDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGML 131
           E++    ++ + +  ++ +S  ++         F E    L++ AE   + +F  TY  +
Sbjct: 74  EERYQIAARQDMQQFLQTSSSTLKFLISRNAAAFQETLETLIKQAENYTSILFCSTYRNM 133

Query: 132 YMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARLLERMFQ-LINPQYHFSE-DYLEC 189
            ++ +   Q+ FT++  Y  G +VN EE +N F+  L   ++  LINP    S  +Y EC
Sbjct: 134 ALEAAASVQEFFTDVGLYLFGADVNPEEFVNRFFDSLFPLVYNHLINPGVTDSSLEYSEC 193

Query: 190 VSKYTDQLKPFGDVPRKLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALM 249
           +      + PFG++P+++  Q+ R+ + +RTF+Q L +G EV N    +  +  C RAL+
Sbjct: 194 IRMARRDVSPFGNIPQRVMGQMGRSLLPSRTFLQALNLGIEVINTTDYLHFSKECSRALL 253

Query: 250 KMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIE 309
           KM YCP+C+GL   +PC  YCLNVM+GCLA+ A+L+  W+ +I ++  +++ + G ++I 
Sbjct: 254 KMQYCPHCQGLALTKPCMGYCLNVMRGCLAHMAELNPHWHAYIRSLEELSDAMHGTYDIG 313

Query: 310 SVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAPENFNTRFRPYNP 369
            V+    + +++A++    N  ++  +V + CG+P     +R+   +P     + +  + 
Sbjct: 314 HVLLNFHLLVNDAVLQAHLNGQKLLEQVNRICGRP-----VRTPTQSPRCSFDQSKEKHG 368

Query: 370 EERPTTAAGTSLDRLVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHSKA 429
            +  T  +  +L     +    L+L +  +  L   +C +E   A   +   CWNG    
Sbjct: 369 MKTTTRNSEETLANRRKEFINSLRLYRSFYGGLADQLCANELAAA---DGLPCWNGEDIV 425

Query: 430 R-YLPEIMNDGLTNQINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAY---------- 478
           + Y   ++ +G+  Q  NPEV V     D  I Q I  L+ +   L+             
Sbjct: 426 KSYTQRVVGNGIKAQSGNPEVKV--KGIDPVINQIIDKLKHVVQLLQGRSPKPDKWELLQ 483

Query: 479 --NGNDVNFQ---DTSDESSGSGSGSG 500
             +G  +  Q   D  DE    GSGSG
Sbjct: 484 LGSGGGMVEQVSGDCDDEDGCGGSGSG 510


>gi|4758462 glypican 3 [Homo sapiens]
          Length = 580

 Score =  182 bits (462), Expect = 7e-46
 Identities = 131/484 (27%), Positives = 226/484 (46%), Gaps = 18/484 (3%)

Query: 29  SCGEVRQAYGAKGFSLADIPYQEIAGEHLRIC-PQEYTCCTTEMEDKLSQQSKLEFENLV 87
           +C +VR  +      L  +P   + G  L++C P+  TCC+ +ME+K    ++L  E L+
Sbjct: 34  TCHQVRSFFQRLQPGLKWVPETPVPGSDLQVCLPKGPTCCSRKMEEKYQLTARLNMEQLL 93

Query: 88  EETSHFVRTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELK 147
           +  S  ++   +     F E F  ++ +A+   N MF   Y  L  Q  E   + FT++ 
Sbjct: 94  QSASMELKFLIIQNAAVFQEAFEIVVRHAKNYTNAMFKNNYPSLTPQAFEFVGEFFTDVS 153

Query: 148 RYYTGGNVNLEEMLNDFWARLLERMF-QLINPQYHFSE-DYLECVSKYTDQLKPFGDVPR 205
            Y  G ++N+++M+N+ +  L   ++ QL+NP    S  D  EC+      LK FG+ P+
Sbjct: 154 LYILGSDINVDDMVNELFDSLFPVIYTQLMNPGLPDSALDINECLRGARRDLKVFGNFPK 213

Query: 206 KLKIQVTRAFIAARTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRP 265
            +  QV+++    R F+Q L +G EV N    +  +  C R L +M YC YC+GL  V+P
Sbjct: 214 LIMTQVSKSLQVTRIFLQALNLGIEVINTTDHLKFSKDCGRMLTRMWYCSYCQGLMMVKP 273

Query: 266 CNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMN 325
           C  YC  VM+GC+A   ++D  W  +I ++  +   +   +++E+V+  +   I ++I  
Sbjct: 274 CGGYCNVVMQGCMAGVVEIDKYWREYILSLEELVNGMYRIYDMENVLLGLFSTIHDSIQY 333

Query: 326 MQENSMQVSAKVFQGCGQPKPAPALRSARSA--PENFNTRFRPYNPEERPTTAAGTSLDR 383
           +Q+N+ +++  + + C   +     R  RSA  PE+    F      +        +L  
Sbjct: 334 VQKNAGKLTTTIGKLCAHSQQ----RQYRSAYYPEDL---FIDKKVLKVAHVEHEETLSS 386

Query: 384 LVTDIKEKLKLSKKVWSALPYTICKDESVTAGTSNEEECWNGHSKA-RYLPEIMNDGLTN 442
              ++ +KLK     +SALP  IC    V     N+  CWNG     RY  +   +G+ N
Sbjct: 387 RRRELIQKLKSFISFYSALPGYICSHSPV---AENDTLCWNGQELVERYSQKAARNGMKN 443

Query: 443 QINNPEVDVDITRPDTFIRQQIMALRVMTNKLKNAYNGNDVNFQDTSDESSGSGSGSGCM 502
           Q N  E  + +  P+  + Q I  L+ +   L+              DE        G  
Sbjct: 444 QFNLHE--LKMKGPEPVVSQIIDKLKHINQLLRTMSMPKGRVLDKNLDEEGFESGDCGDD 501

Query: 503 DDVC 506
           +D C
Sbjct: 502 EDEC 505


>gi|4502315 ATPase, H+ transporting, lysosomal V1 subunit C1 [Homo
           sapiens]
          Length = 382

 Score = 34.3 bits (77), Expect = 0.31
 Identities = 49/230 (21%), Positives = 96/230 (41%), Gaps = 18/230 (7%)

Query: 42  FSLADIPYQEIAGEHLRICPQEYTCCTTEMEDKLSQQSKLE--FENLVEETSHFVRTTFV 99
           + +A  P ++       I  +  T    +++ + S  + L+   +NL  + +  + T  +
Sbjct: 107 WDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSL 166

Query: 100 SRHKKFDEFFRE------LLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGG 153
           +   K D+F  +      LL    K  ++ +++ Y  L         ++ +E +  Y   
Sbjct: 167 AEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCN 226

Query: 154 NVNLEEMLNDFWARLLERMFQLINPQYHFSE---DYLECVSKYTDQLKPFGDVPRKLKIQ 210
                + ++DF  +  E  F + + QY+  E   D  E     TD+ K FG + R LK+ 
Sbjct: 227 VTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVN 286

Query: 211 VTRAFI------AARTFVQG-LTVGREVANRVSKVSPTPGCIRALMKMLY 253
            + AFI      A R FV+  L  G  V  +   + P    ++ L ++L+
Sbjct: 287 FSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLH 336


>gi|30061567 La ribonucleoprotein domain family member 2 isoform 1
           [Homo sapiens]
          Length = 914

 Score = 33.1 bits (74), Expect = 0.68
 Identities = 34/108 (31%), Positives = 46/108 (42%), Gaps = 13/108 (12%)

Query: 67  CTTEMEDKLSQQSKLEFENLVEETSHFVRTTFVSRHKKFDEFFRELL-----ENAEKSLN 121
           C +E + +L      E   L    S F+R  F   +KK  E FR+L      EN    L 
Sbjct: 719 CLSERK-RLGIGQSQEMNTLFRFWSFFLRDHF---NKKMYEEFRQLAWEDAKENYRYGLE 774

Query: 122 DMF-VRTYGMLYMQNSEVFQDLFTELKRYYTGGNVNLEEMLNDFWARL 168
            +F   +YG+      E+FQD   E K+ Y  G +     L  FWA L
Sbjct: 775 CLFRFYSYGLEKKFRREIFQDFQEETKKDYESGQL---YGLEKFWAYL 819


>gi|239049391 membrane metallo-endopeptidase-like 1 [Homo sapiens]
          Length = 779

 Score = 33.1 bits (74), Expect = 0.68
 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%)

Query: 219 RTFVQGLTVGREVANRVSKVSPTPGCIRALMKMLYCPYCRGLPTVRPCNNY 269
           RTFV+    G   A  VS+V  TPGC+ A  ++L        PT  PC+++
Sbjct: 69  RTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQ----NMDPTTEPCDDF 115


>gi|45439342 peptidylprolyl isomerase (cyclophilin)-like 5 isoform 1
           [Homo sapiens]
          Length = 414

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 29/121 (23%), Positives = 45/121 (37%), Gaps = 17/121 (14%)

Query: 303 EGPFNIESVMDPIDVKISEAIMNMQENSMQVSAKVFQGCGQPKPAPALRSARSAP-ENFN 361
           EG   +     P+D+ +S+AI +  +  +       +GC    P   L   +++  ENF 
Sbjct: 76  EGKATVRLKEPPVDICLSKAISSSLKGFLSAMRLAHRGCNVDTPVSTLTPVKTSEFENFK 135

Query: 362 TRF-------------RPYNPEERPTTAAG---TSLDRLVTDIKEKLKLSKKVWSALPYT 405
           T+               PY+ E   T+  G     +  L      KL LS      LP T
Sbjct: 136 TKMVITSKKDYPLSKNFPYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPAT 195

Query: 406 I 406
           I
Sbjct: 196 I 196


>gi|50345881 cytoplasmic polyadenylation element binding protein 3
           [Homo sapiens]
          Length = 698

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 409 DESVTAGTSNEEECWNGHSKARYLPEIMNDGLTNQINNPEVDVDITR 455
           D+++++G S+   C NG    RY  ++   GL   I+  E+     R
Sbjct: 417 DQALSSGLSSPTRCQNGERVERYSRKVFVGGLPPDIDEDEITASFRR 463


>gi|13994250 tektin 3 [Homo sapiens]
          Length = 490

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

Query: 95  RTTFVSRHKKFDEFFRELLENAEKSLNDMFVRTYGMLYMQNSEVFQDLFTELKRYYTGGN 154
           RTTF +R+   D+++R  L N ++S           L +  S + QD + + ++      
Sbjct: 87  RTTFFTRYTP-DDWYRSNLTNYQESNTSR--HNSEKLRVDTSRLIQDKYQQTRKTQADTT 143

Query: 155 VNLEEMLND--FW 165
            NL E +ND  FW
Sbjct: 144 QNLGERVNDIGFW 156


>gi|34147335 armadillo repeat containing, X-linked 6 [Homo sapiens]
          Length = 300

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 17/87 (19%)

Query: 275 KGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVS 334
           + C      LD    LFI   LL AE  +  F         D+    A ++M  N+    
Sbjct: 116 QNCKNGSCVLDLSKCLFIQGKLLFAEPKDAGFPFSQ-----DINSHLASLSMARNT---- 166

Query: 335 AKVFQGCGQPKPAPALRSARSAPENFN 361
                    P P P +R A  AP+N N
Sbjct: 167 --------SPTPDPTVREALCAPDNLN 185


>gi|57546906 armadillo repeat containing, X-linked 6 [Homo sapiens]
          Length = 300

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 17/87 (19%)

Query: 275 KGCLANQADLDTEWNLFIDAMLLVAERLEGPFNIESVMDPIDVKISEAIMNMQENSMQVS 334
           + C      LD    LFI   LL AE  +  F         D+    A ++M  N+    
Sbjct: 116 QNCKNGSCVLDLSKCLFIQGKLLFAEPKDAGFPFSQ-----DINSHLASLSMARNT---- 166

Query: 335 AKVFQGCGQPKPAPALRSARSAPENFN 361
                    P P P +R A  AP+N N
Sbjct: 167 --------SPTPDPTVREALCAPDNLN 185


>gi|223029410 talin 1 [Homo sapiens]
          Length = 2541

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 19/51 (37%), Positives = 28/51 (54%), Gaps = 4/51 (7%)

Query: 107  EFFRELLENAEKSLNDMFVRTYGML--YMQNSEVFQDLFTELKRYYTGGNV 155
            E  RELLEN  + +NDM    +G L   M+NS+V  +  T + +    GN+
Sbjct: 1371 ETVRELLENPVQPINDM--SYFGCLDSVMENSKVLGEAMTGISQNAKNGNL 1419


>gi|34577055 F-box only protein 30 [Homo sapiens]
          Length = 745

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 13/33 (39%), Positives = 17/33 (51%), Gaps = 1/33 (3%)

Query: 55  EHLRICPQEYTCCTTEMED-KLSQQSKLEFENL 86
           EHL +CP    CCT E     +S   +  +ENL
Sbjct: 78  EHLEMCPASVVCCTMEWNRWPVSYADRKSYENL 110


>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
          Length = 641

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 16/63 (25%), Positives = 25/63 (39%)

Query: 245 IRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEG 304
           +R L   +  P C G    RPC + C  + + C      +D  W  F+D         EG
Sbjct: 86  LRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEG 145

Query: 305 PFN 307
            ++
Sbjct: 146 CYD 148


>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
          Length = 652

 Score = 29.3 bits (64), Expect = 9.9
 Identities = 16/63 (25%), Positives = 25/63 (39%)

Query: 245 IRALMKMLYCPYCRGLPTVRPCNNYCLNVMKGCLANQADLDTEWNLFIDAMLLVAERLEG 304
           +R L   +  P C G    RPC + C  + + C      +D  W  F+D         EG
Sbjct: 97  LRLLGCAVLAPRCEGGWVRRPCRHICEGLREVCQPAFDAIDMAWPYFLDCHRYFTREDEG 156

Query: 305 PFN 307
            ++
Sbjct: 157 CYD 159


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,681,193
Number of Sequences: 37866
Number of extensions: 910144
Number of successful extensions: 2547
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2526
Number of HSP's gapped (non-prelim): 19
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.