Search of human proteins with 4885559

Search of human proteins with 4885559

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885559 protein phosphatase 1, regulatory (inhibitor)
subunit 3C [Homo sapiens]
         (317 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit...   664   0.0  
gi|153792466 protein phosphatase 1, regulatory (inhibitor) subun...   223   2e-58
gi|167614502 protein phosphatase 1, regulatory (inhibitor) subun...    93   4e-19
gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo sa...    89   4e-18
gi|223278393 protein phosphatase 1, regulatory (inhibitor) subun...    52   5e-07
gi|239757810 PREDICTED: similar to protein phosphatase 1, regula...    48   1e-05
gi|58761532 protein phosphatase 1, regulatory (inhibitor) subuni...    48   1e-05
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]              31   1.3  
gi|75677325 kinase suppressor of ras [Homo sapiens]                    29   6.3  
gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]     28   8.2  
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    28   8.2  

>gi|4885559 protein phosphatase 1, regulatory (inhibitor) subunit 3C
           [Homo sapiens]
          Length = 317

 Score =  664 bits (1714), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS 60
           MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS
Sbjct: 1   MSCTRMIQVLDPRPLTSSVMPVDVAMRLCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKS 60

Query: 61  CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN 120
           CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN
Sbjct: 61  CLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLN 120

Query: 121 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF 180
           DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF
Sbjct: 121 DISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSF 180

Query: 181 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA 240
           EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA
Sbjct: 181 EKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIEFCISYHA 240

Query: 241 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL 300
           NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL
Sbjct: 241 NGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPRLASGL 300

Query: 301 FPEWQSWGRMENLASYR 317
           FPEWQSWGRMENLASYR
Sbjct: 301 FPEWQSWGRMENLASYR 317


>gi|153792466 protein phosphatase 1, regulatory (inhibitor) subunit
           3B [Homo sapiens]
          Length = 285

 Score =  223 bits (567), Expect = 2e-58
 Identities = 113/263 (42%), Positives = 165/263 (62%), Gaps = 12/263 (4%)

Query: 56  KPLKSCLNI--KHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDLQ 113
           KPL+ C+ +  K++A           + KKRV FAD++GL+LT + VFS+  ++P  D+ 
Sbjct: 32  KPLRPCIQLSSKNEASGMVAPAVQEKKVKKRVSFADNQGLALTMVKVFSEF-DDPL-DMP 89

Query: 114 FDLLDLNDISSALKHHEEKNLILDFPQPSTDYLSFRSHFQKNFVCLENCSLQERTVTGTV 173
           F++ +L D   +L   E ++ +LDF QPS DYL FR+  Q + VCLENC L+++ + GTV
Sbjct: 90  FNITELLDNIVSLTTAESESFVLDFSQPSADYLDFRNRLQADHVCLENCVLKDKAIAGTV 149

Query: 174 KVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNVYGGTDSDTFSFAIDLPPVIPTEQKIE 233
           KV+N++FEK V+IR+TFD+WK+YTD  C Y+K+ Y G+D DTFSF I LP  I + +++E
Sbjct: 150 KVQNLAFEKTVKIRMTFDTWKSYTDFPCQYVKDTYAGSDRDTFSFDISLPEKIQSYERME 209

Query: 234 FCISYHANGQVFWDNNDGQNYRIVHVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGS 293
           F + Y  NGQ +WD+N G+NYRI+  + K        + Q      + P   +    FGS
Sbjct: 210 FAVYYECNGQTYWDSNRGKNYRIIRAELK--------STQGMTKPHSGPDLGISFDQFGS 261

Query: 294 PRLASGLFPEWQSWGRMENLASY 316
           PR + GLFPEW S+   E L  Y
Sbjct: 262 PRCSYGLFPEWPSYLGYEKLGPY 284


>gi|167614502 protein phosphatase 1, regulatory (inhibitor) subunit
           3A [Homo sapiens]
          Length = 1122

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 62/178 (34%), Positives = 90/178 (50%), Gaps = 12/178 (6%)

Query: 83  KRVVFADSKGLSLTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNL--ILDFPQ 140
           +RV FADS G +L ++  F D  E P+    FDL       + + H EE  L  + D P 
Sbjct: 62  RRVSFADSFGFNLVSVKEF-DCWELPSASTTFDL------GTDIFHTEEYVLAPLFDLPS 114

Query: 141 PSTDYLSFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVD 200
              D +  +   QK  +      L   ++ G ++V NVSFEK V +R++ D W+ + D+ 
Sbjct: 115 SKEDLMQ-QLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDIL 173

Query: 201 CVYMKNVYGGTDSDTFSFAIDL-PPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRIV 257
             Y+ N   G ++D FSF I L PP      K+EFCI Y  +   FW NN+G NY  +
Sbjct: 174 AEYVPNSCDG-ETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFI 230


>gi|5453948 protein phosphatase 1, regulatory subunit 3D [Homo
           sapiens]
          Length = 299

 Score = 89.4 bits (220), Expect = 4e-18
 Identities = 67/231 (29%), Positives = 104/231 (45%), Gaps = 10/231 (4%)

Query: 33  SPPVKSFLGPYDEFQRRHFVNKLKPLKSCLNIKHKAKSQNDWKCSHNQAKK-RVVFADSK 91
           +PP        D   R   + + + L S    + KA       C    ++K RV FAD+ 
Sbjct: 50  APPPTPAPSGCDPRLRPIILRRARSLPSSPERRQKAAGAPGAACRPGCSQKLRVRFADAL 109

Query: 92  GLSLTAIHVFS--DLPEEPAWDLQFDLLDLND---ISSALKHHEEKNLILDFPQPSTDYL 146
           GL L  + VF+  D P  P   L    L +N     SS         L+ DFP P  +  
Sbjct: 110 GLELAQVKVFNAGDDPSVPLHVLS--RLAINSDLCCSSQDLEFTLHCLVPDFPPP-VEAA 166

Query: 147 SFRSHFQKNFVCLENCSLQERTVTGTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKN 206
            F    Q+  VCLE  +  +  ++GTV+V NV+FEK+V +R TF  W++  +    +   
Sbjct: 167 DFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGP 226

Query: 207 VYGGTDSDTFSFAIDLPP-VIPTEQKIEFCISYHANGQVFWDNNDGQNYRI 256
                  D F+F   +PP ++    ++ F + Y   G  +WDNND ++Y +
Sbjct: 227 AGPEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSL 277


>gi|223278393 protein phosphatase 1, regulatory (inhibitor) subunit
           3G [Homo sapiens]
          Length = 358

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 59/228 (25%), Positives = 90/228 (39%), Gaps = 56/228 (24%)

Query: 80  QAKKRVVFADSKGLSLTAIHVFSDLPEEP----------------AWDLQF--DLLDLND 121
           + KKRV FAD+ GLSL ++  FS+  EEP                A DL+    LL    
Sbjct: 127 KCKKRVQFADTLGLSLASVKHFSEA-EEPQVPPAVLSRLRSFPMRAEDLEQLGGLLAAAA 185

Query: 122 ISSALKHHEEK-NLILDFPQPSTDYLSFRSHFQKNFVCLEN--CSLQERT-VTGTVKVKN 177
           +++ L     +   +   P PS    +     Q+  VCLE   CS      V G+ +V +
Sbjct: 186 VAAPLSAPPSRLRPLFQLPGPS----AAAERLQRQRVCLERVQCSTASGAEVKGSGRVLS 241

Query: 178 VSFEKKVQIRITFDSWKNYTDVDCVYMKNVY--------------GGTDS------DTFS 217
               + V +R TF  W+++ DV                       G  D+      + F 
Sbjct: 242 CPGPRAVTVRYTFTEWRSFLDVPAELQPEPLEPQQPEAPSGASEPGSGDAKKEPGAECFH 301

Query: 218 FAIDLPPVIPTEQK---------IEFCISYHANGQVFWDNNDGQNYRI 256
           F++ LPP +  E +         + F + Y      +WDNN G NY +
Sbjct: 302 FSLCLPPGLQPEDEEDADERGVAVHFAVCYRCAQGEYWDNNAGANYTL 349


>gi|239757810 PREDICTED: similar to protein phosphatase 1,
           regulatory (inhibitor) subunit 3F [Homo sapiens]
          Length = 724

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 36/158 (22%), Positives = 57/158 (36%), Gaps = 33/158 (20%)

Query: 171 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNV-----YGGTDS------------ 213
           G V+V N SFEK V +R + D W ++ D    Y+         GGT +            
Sbjct: 166 GLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLG 225

Query: 214 ---------------DTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRI-V 257
                          D F+F +          +++F + Y      FW NN G+NY + +
Sbjct: 226 PGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLL 285

Query: 258 HVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPR 295
            +   P     +  PQ     Q  P+ E +  +    R
Sbjct: 286 RIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEAR 323


>gi|58761532 protein phosphatase 1, regulatory (inhibitor) subunit
           3F [Homo sapiens]
          Length = 799

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 36/158 (22%), Positives = 57/158 (36%), Gaps = 33/158 (20%)

Query: 171 GTVKVKNVSFEKKVQIRITFDSWKNYTDVDCVYMKNV-----YGGTDS------------ 213
           G V+V N SFEK V +R + D W ++ D    Y+         GGT +            
Sbjct: 166 GLVRVLNRSFEKAVHVRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLG 225

Query: 214 ---------------DTFSFAIDLPPVIPTEQKIEFCISYHANGQVFWDNNDGQNYRI-V 257
                          D F+F +          +++F + Y      FW NN G+NY + +
Sbjct: 226 PGQASASSPDDGGRTDRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLL 285

Query: 258 HVQWKPDGVQTQMAPQDCAFHQTSPKTELESTIFGSPR 295
            +   P     +  PQ     Q  P+ E +  +    R
Sbjct: 286 RIAPAPTPTDAEGLPQQQQLPQLEPQPECQGPVEAEAR 323


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 95  LTAIHVFSDLPEEPAWDLQFDLLDLNDISSALKHHEEKNLIL 136
           LTA H F  LP +  W +   +L+L+DI+      + K +I+
Sbjct: 430 LTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIII 471


>gi|75677325 kinase suppressor of ras [Homo sapiens]
          Length = 762

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 21/70 (30%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 64  IKHKAKSQNDWKCSHNQAKKRVVFADSKGLS----LTAIHVFSDLPEEPAWDLQFDLLD- 118
           +K++A   + W+    +  KRV+ + S G      L+A   F DL E P++ L  D+L+ 
Sbjct: 684 LKNQAAEASIWQIGSGEGMKRVLTSVSLGKEVSEILSACWAF-DLQERPSFSLLMDMLEK 742

Query: 119 LNDISSALKH 128
           L  ++  L H
Sbjct: 743 LPKLNRRLSH 752


>gi|4504503 hydroxysteroid (17-beta) dehydrogenase 2 [Homo sapiens]
          Length = 387

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 8/44 (18%)

Query: 28  LCLAHSPPVKSFLGPYDEFQRRHFVNKLKPLKSCL---NIKHKA 68
           +CLAH  P+    G YD F +RHF  + KP+   L   N K KA
Sbjct: 348 ICLAHYLPI----GIYDYFAKRHF-GQDKPMPRALRMPNYKKKA 386


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 23/89 (25%), Positives = 36/89 (40%)

Query: 53  NKLKPLKSCLNIKHKAKSQNDWKCSHNQAKKRVVFADSKGLSLTAIHVFSDLPEEPAWDL 112
           NK +  K    +  K+++  + K    + K R     +K   L    V+SD  EE   D 
Sbjct: 264 NKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDDK 323

Query: 113 QFDLLDLNDISSALKHHEEKNLILDFPQP 141
             +  D +  +S+    EEK  I    QP
Sbjct: 324 SSEKSDRSSRTSSSDEEEEKEEIPPKSQP 352


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,158,402
Number of Sequences: 37866
Number of extensions: 593314
Number of successful extensions: 1133
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1116
Number of HSP's gapped (non-prelim): 14
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.