Guide to the Human Genome
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Search of human proteins with 4759088

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759088 SEC22 vesicle trafficking protein homolog C isoform
b [Homo sapiens]
         (250 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759088 SEC22 vesicle trafficking protein homolog C isoform b...   520   e-148
gi|14591921 SEC22 vesicle trafficking protein homolog C isoform ...   488   e-138
gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo sa...   160   1e-39
gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo sa...    65   4e-11
gi|30578410 source of immunodominant MHC-associated peptides [Ho...    28   7.5  

>gi|4759088 SEC22 vesicle trafficking protein homolog C isoform b
           [Homo sapiens]
          Length = 250

 Score =  520 bits (1339), Expect = e-148
 Identities = 250/250 (100%), Positives = 250/250 (100%)

Query: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60
           MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI
Sbjct: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60

Query: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120
           HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ
Sbjct: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120

Query: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR 180
           KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR
Sbjct: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR 180

Query: 181 MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQDPR 240
           MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQDPR
Sbjct: 181 MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQDPR 240

Query: 241 SWFCWLDQTS 250
           SWFCWLDQTS
Sbjct: 241 SWFCWLDQTS 250


>gi|14591921 SEC22 vesicle trafficking protein homolog C isoform a
           [Homo sapiens]
          Length = 303

 Score =  488 bits (1256), Expect = e-138
 Identities = 237/237 (100%), Positives = 237/237 (100%)

Query: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60
           MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI
Sbjct: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60

Query: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120
           HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ
Sbjct: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120

Query: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR 180
           KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR
Sbjct: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNFR 180

Query: 181 MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQ 237
           MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQ
Sbjct: 181 MEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIFQ 237


>gi|14591919 SEC22 vesicle trafficking protein homolog A [Homo
           sapiens]
          Length = 307

 Score =  160 bits (405), Expect = 1e-39
 Identities = 92/241 (38%), Positives = 139/241 (57%), Gaps = 4/241 (1%)

Query: 1   MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI 60
           MS+I  A V+RVRDGLPLSASTD+  +    E R+  K L+ +LAQ P R + +   ++I
Sbjct: 1   MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI 60

Query: 61  HFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSIIQ 120
           +F S   V+ M +C+   P  +AF FL+ L  EF  +Y+      A RPY F+EFD+ IQ
Sbjct: 61  NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ 120

Query: 121 KVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHT----PMHLEPA 176
           + K  +N   S   + +L  +Q E+KL+PP  +++ +   ANGV +  +          +
Sbjct: 121 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS 180

Query: 177 PNFRMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVACIF 236
            + R+EP T  GI+  IL+++C ALNLIRG H  E  LQ   ++   I+AF +   AC++
Sbjct: 181 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY 240

Query: 237 Q 237
           Q
Sbjct: 241 Q 241


>gi|94429050 SEC22 vesicle trafficking protein homolog B [Homo
           sapiens]
          Length = 215

 Score = 65.5 bits (158), Expect = 4e-11
 Identities = 41/124 (33%), Positives = 63/124 (50%), Gaps = 4/124 (3%)

Query: 3   VIFFACVVRVRDGLPLSAST--DFYHTQDFLEWRRRLKSLALRL-AQYPGRGSAEGCDFS 59
           ++    + RV DGLPL+AS   D    +D  +++ + K L  +L  Q P R + E    +
Sbjct: 1   MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGAMT 60

Query: 60  IHFSSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSII 119
            H+     V  + +C    P  +AF +LE L  EF   +    +   SRPY+F+EFD+ I
Sbjct: 61  FHYIIEQGVCDLVLCEAAFPKTLAFAYLEDLHSEFDEQHGKK-VPTVSRPYSFIEFDTFI 119

Query: 120 QKVK 123
           QK K
Sbjct: 120 QKTK 123


>gi|30578410 source of immunodominant MHC-associated peptides [Homo
           sapiens]
          Length = 826

 Score = 28.1 bits (61), Expect = 7.5
 Identities = 17/60 (28%), Positives = 29/60 (48%), Gaps = 4/60 (6%)

Query: 79  PAAMAFCFLETLWWE----FTASYDTTCIGLASRPYAFLEFDSIIQKVKWHFNYVSSSQM 134
           PA ++    +   W+    FT  +     G +SR +A + F+SII +    FNY S+  +
Sbjct: 55  PAGLSGGLSQPAGWQSLLSFTILFLAWLAGFSSRLFAVIRFESIIHEFDPWFNYRSTHHL 114


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.138    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,784,657
Number of Sequences: 37866
Number of extensions: 404806
Number of successful extensions: 1108
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1101
Number of HSP's gapped (non-prelim): 5
length of query: 250
length of database: 18,247,518
effective HSP length: 100
effective length of query: 150
effective length of database: 14,460,918
effective search space: 2169137700
effective search space used: 2169137700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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