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Search of human proteins with 4758662
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4
isoform a [Homo sapiens]
(616 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isof... 1258 0.0
gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4 is... 1236 0.0
gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Hom... 775 0.0
gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1 is... 158 1e-38
gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1 iso... 158 1e-38
gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [H... 153 4e-37
gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2 iso... 142 1e-33
gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8 is... 131 2e-30
gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isof... 130 4e-30
gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Hom... 118 2e-26
gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8 is... 108 2e-23
gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6 is... 102 1e-21
gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6 is... 102 1e-21
gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens] 30 8.6
gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens] 30 8.6
>gi|4758662 ectonucleoside triphosphate diphosphohydrolase 4 isoform
a [Homo sapiens]
Length = 616
Score = 1258 bits (3254), Expect = 0.0
Identities = 616/616 (100%), Positives = 616/616 (100%)
Query: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR 60
MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
Sbjct: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR 60
Query: 61 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI 120
LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
Sbjct: 61 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI 120
Query: 121 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA 180
RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
Sbjct: 121 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA 180
Query: 181 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI 240
GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
Sbjct: 181 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI 240
Query: 241 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKN 300
EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKN
Sbjct: 241 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKN 300
Query: 301 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP 360
LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP
Sbjct: 301 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP 360
Query: 361 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP 420
DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP
Sbjct: 361 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP 420
Query: 421 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH 480
IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH
Sbjct: 421 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH 480
Query: 481 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL 540
ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL
Sbjct: 481 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL 540
Query: 541 RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA 600
RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA
Sbjct: 541 RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA 600
Query: 601 LWMEEGLPAQNAPGTL 616
LWMEEGLPAQNAPGTL
Sbjct: 601 LWMEEGLPAQNAPGTL 616
>gi|193083168 ectonucleoside triphosphate diphosphohydrolase 4
isoform b [Homo sapiens]
Length = 608
Score = 1236 bits (3199), Expect = 0.0
Identities = 608/616 (98%), Positives = 608/616 (98%), Gaps = 8/616 (1%)
Query: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR 60
MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR
Sbjct: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQIMVISVLAAAVSLLYFSVVIIRNKYGR 60
Query: 61 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI 120
LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI
Sbjct: 61 LTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDI 120
Query: 121 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA 180
RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA
Sbjct: 121 RQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTA 180
Query: 181 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI 240
GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI
Sbjct: 181 GMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHI 240
Query: 241 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKN 300
EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKT EEVAKN
Sbjct: 241 EDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKT--------EEVAKN 292
Query: 301 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP 360
LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP
Sbjct: 293 LLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTP 352
Query: 361 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP 420
DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP
Sbjct: 353 DMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPP 412
Query: 421 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH 480
IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH
Sbjct: 413 IHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASH 472
Query: 481 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL 540
ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL
Sbjct: 473 ADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFLPL 532
Query: 541 RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA 600
RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA
Sbjct: 533 RDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSAAA 592
Query: 601 LWMEEGLPAQNAPGTL 616
LWMEEGLPAQNAPGTL
Sbjct: 593 LWMEEGLPAQNAPGTL 608
>gi|9966821 ectonucleoside triphosphate diphosphohydrolase 7 [Homo
sapiens]
Length = 604
Score = 775 bits (2001), Expect = 0.0
Identities = 379/611 (62%), Positives = 463/611 (75%), Gaps = 18/611 (2%)
Query: 1 MGRIGISCLFPASWHFSISPVGCPRILNTNLRQ-IMVISVLAAAVSLLYFSVVIIRNKYG 59
M RI S L PASW+F++ V + LRQ + + + + LL ++ R+
Sbjct: 1 MARISFSYLCPASWYFTVPTV------SPFLRQRVAFLGLFFISCLLLLMLIIDFRHWSA 54
Query: 60 RLTRDKKFQRYLARVTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLD 119
L RD++++RYLARV ++EATDT +PN+NYG+VVDCGSSGSR+FVY WPRHNGNPHDLLD
Sbjct: 55 SLPRDRQYERYLARVGELEATDTEDPNLNYGLVVDCGSSGSRIFVYFWPRHNGNPHDLLD 114
Query: 120 IRQMRDKNRKPVVMKIKPGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCT 179
I+QMRD+N +PVV KIKPGIS A +PE SDY+ PLL+FAA HVP KHKETPLYILCT
Sbjct: 115 IKQMRDRNSQPVVKKIKPGISAMADTPEHASDYLRPLLSFAAAHVPVKKHKETPLYILCT 174
Query: 180 AGMRILPESQQKAILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEH 239
AGMR+LPE +Q AIL DL+ D+P+ FDFLFS S AEVISGKQEGVYAWIGINFVLGRF+H
Sbjct: 175 AGMRLLPERKQLAILADLVKDLPLEFDFLFSQSQAEVISGKQEGVYAWIGINFVLGRFDH 234
Query: 240 IEDDD-EAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVA 298
++ D EA E+ A R+RT GILDMGG S QIAYEVP + S ++QEE A
Sbjct: 235 EDESDAEATQEL---------AAGRRRTVGILDMGGASLQIAYEVPTSTSVLPAKQEEAA 285
Query: 299 KNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGL 358
K LLAEFNLGCDV TEHVYRVYV TFLGFGGN ARQRYED + T+ KNRLLG++TGL
Sbjct: 286 KILLAEFNLGCDVQHTEHVYRVYVTTFLGFGGNFARQRYEDLVLNETLNKNRLLGQKTGL 345
Query: 359 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTNETQTSLNGVYQ 418
+PD P+LDPCLP+ + D +++N Q +++RG GD+ C + P + ++N +Q SLNG+YQ
Sbjct: 346 SPDNPFLDPCLPVGLTDVVERNSQVLHVRGRGDWVSCGAMLSPLLARSNTSQASLNGIYQ 405
Query: 419 PPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYA 478
PI F NSEFYGFSEF+YCTEDVLR+GG Y+ F KAA+DYC WS+L +RF GL++
Sbjct: 406 SPIDFNNSEFYGFSEFFYCTEDVLRIGGRYHGPTFAKAAQDYCGMAWSVLTQRFKNGLFS 465
Query: 479 SHADLHRLKYQCFKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILYRTRFL 538
SHAD HRLKYQCFKSAWM++V H GF FP +Y +L+TA VYD+EVQWTLGAILY+TRFL
Sbjct: 466 SHADEHRLKYQCFKSAWMYQVLHEGFHFPYDYPNLRTAQLVYDREVQWTLGAILYKTRFL 525
Query: 539 PLRDIQQEAFRASHTHWRGVSFVYNHYLFSGCFLVVLLAILLYLLRLRRIHRRTPRSSSA 598
PLRD++QE R +H W +SFVYNHYLF C LVVLLAI LYLLRLRRIH R R+S+
Sbjct: 526 PLRDLRQEGVRQAHGSWFRLSFVYNHYLFFACILVVLLAIFLYLLRLRRIHHRQTRASAP 585
Query: 599 A-ALWMEEGLP 608
LW+EE +P
Sbjct: 586 LDLLWLEEVVP 596
>gi|147905700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 2 [Homo sapiens]
Length = 517
Score = 158 bits (400), Expect = 1e-38
Identities = 138/512 (26%), Positives = 245/512 (47%), Gaps = 74/512 (14%)
Query: 86 NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLL-DIRQMRDKNRKPVVMKIKPGISEFAT 144
NV YGIV+D GSS + +++Y WP N ++ + + R K PGIS+F
Sbjct: 53 NVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKG---------PGISKFVQ 103
Query: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRIL-PESQQKA-----ILEDLL 198
++ Y++ + A E +PR++H+ETP+Y+ TAGMR+L ES++ A ++E L
Sbjct: 104 KVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSL 163
Query: 199 TDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESS 258
++ P FDF A +I+G++EG Y WI IN++LG+F + +I E++
Sbjct: 164 SNYP--FDF----QGARIITGQEEGAYGWITINYLLGKF------SQKTRWFSIVPYETN 211
Query: 259 EAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVY 318
+ T G LD+GG STQ+ + VP+ +Q E N L G D Y
Sbjct: 212 ----NQETFGALDLGGASTQVTF-VPQ------NQTIESPDNALQFRLYGKD-------Y 253
Query: 319 RVYVATFLGFGGNAA---RQRYEDRIFANTIQKNRLL--GKQTGLTPDMPYLDPCLPLDI 373
VY +FL +G + A + + ++ +N I ++ G + + Y PC
Sbjct: 254 NVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTK--- 310
Query: 374 KDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKT--NETQTSLNGVYQPPIHFQNSEFYGF 431
+ E+ Q ++G G++ C ++I N + +Q + NG++ PP+ +F F
Sbjct: 311 RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPL---QGDFGAF 367
Query: 432 SEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCF 491
S FY+ + + + K T+ K +CA W ++ YA + + +Y CF
Sbjct: 368 SAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTS-----YAGVKEKYLSEY-CF 421
Query: 492 KSAWMFEVFHRGFSFPV-NYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRA 550
++ + +G+ F +++ + ++ + WTLG +L T +P Q +
Sbjct: 422 SGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAE--QPLSTPL 479
Query: 551 SHTHWRGVSFVYNHYLFS-GCFLVVLLAILLY 581
SH+ ++V+ LFS F V ++ +L++
Sbjct: 480 SHS-----TYVFLMVLFSLVLFTVAIIGLLIF 506
>gi|45580700 ectonucleoside triphosphate diphosphohydrolase 1
isoform 1 [Homo sapiens]
Length = 510
Score = 158 bits (400), Expect = 1e-38
Identities = 138/512 (26%), Positives = 245/512 (47%), Gaps = 74/512 (14%)
Query: 86 NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLL-DIRQMRDKNRKPVVMKIKPGISEFAT 144
NV YGIV+D GSS + +++Y WP N ++ + + R K PGIS+F
Sbjct: 46 NVKYGIVLDAGSSHTSLYIYKWPAEKENDTGVVHQVEECRVKG---------PGISKFVQ 96
Query: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRIL-PESQQKA-----ILEDLL 198
++ Y++ + A E +PR++H+ETP+Y+ TAGMR+L ES++ A ++E L
Sbjct: 97 KVNEIGIYLTDCMERAREVIPRSQHQETPVYLGATAGMRLLRMESEELADRVLDVVERSL 156
Query: 199 TDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESS 258
++ P FDF A +I+G++EG Y WI IN++LG+F + +I E++
Sbjct: 157 SNYP--FDF----QGARIITGQEEGAYGWITINYLLGKF------SQKTRWFSIVPYETN 204
Query: 259 EAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVY 318
+ T G LD+GG STQ+ + VP+ +Q E N L G D Y
Sbjct: 205 ----NQETFGALDLGGASTQVTF-VPQ------NQTIESPDNALQFRLYGKD-------Y 246
Query: 319 RVYVATFLGFGGNAA---RQRYEDRIFANTIQKNRLL--GKQTGLTPDMPYLDPCLPLDI 373
VY +FL +G + A + + ++ +N I ++ G + + Y PC
Sbjct: 247 NVYTHSFLCYGKDQALWQKLAKDIQVASNEILRDPCFHPGYKKVVNVSDLYKTPCTK--- 303
Query: 374 KDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKT--NETQTSLNGVYQPPIHFQNSEFYGF 431
+ E+ Q ++G G++ C ++I N + +Q + NG++ PP+ +F F
Sbjct: 304 RFEMTLPFQQFEIQGIGNYQQCHQSILELFNTSYCPYSQCAFNGIFLPPL---QGDFGAF 360
Query: 432 SEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCF 491
S FY+ + + + K T+ K +CA W ++ YA + + +Y CF
Sbjct: 361 SAFYFVMKFLNLTSEKVSQEKVTEMMKKFCAQPWEEIKTS-----YAGVKEKYLSEY-CF 414
Query: 492 KSAWMFEVFHRGFSFPV-NYKSLKTALQVYDKEVQWTLGAILYRTRFLPLRDIQQEAFRA 550
++ + +G+ F +++ + ++ + WTLG +L T +P Q +
Sbjct: 415 SGTYILSLLLQGYHFTADSWEHIHFIGKIQGSDAGWTLGYMLNLTNMIPAE--QPLSTPL 472
Query: 551 SHTHWRGVSFVYNHYLFS-GCFLVVLLAILLY 581
SH+ ++V+ LFS F V ++ +L++
Sbjct: 473 SHS-----TYVFLMVLFSLVLFTVAIIGLLIF 499
>gi|166197702 ectonucleoside triphosphate diphosphohydrolase 3 [Homo
sapiens]
Length = 529
Score = 153 bits (387), Expect = 4e-37
Identities = 129/480 (26%), Positives = 218/480 (45%), Gaps = 63/480 (13%)
Query: 74 VTDIEATDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVM 133
V I + P + YGIV+D GSS + V+VY WP N ++ +
Sbjct: 42 VIQIHKQEVLPPGLKYGIVLDAGSSRTTVYVYQWPAEKENNTGVVS---------QTFKC 92
Query: 134 KIK-PGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKA 192
+K GIS + +P+ V + VP H TP+++ TAGMR+L Q +
Sbjct: 93 SVKGSGISSYGNNPQDVPRAFEECMQKVKGQVPSHLHGSTPIHLGATAGMRLL-RLQNET 151
Query: 193 ILEDLLTDIPVHFDFL-FSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVN 251
++L I +F F A++ISG++EGVY WI N+++G F + + + V+
Sbjct: 152 AANEVLESIQSYFKSQPFDFRGAQIISGQEEGVYGWITANYLMGNF---LEKNLWHMWVH 208
Query: 252 IPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDV 311
G E T G LD+GG STQI SF + ++ ++ + + + +L
Sbjct: 209 PHGVE---------TTGALDLGGASTQI--------SFVAGEKMDLNTSDIMQVSL---- 247
Query: 312 HQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKNRLLG----KQTGLTPDMPYL-D 366
+VY +Y +F +G N A +++ + N+ KN L + ++ M ++ D
Sbjct: 248 --YGYVYTLYTHSFQCYGRNEAEKKFLAMLLQNSPTKNHLTNPCYPRDYSISFTMGHVFD 305
Query: 367 PCLPLDIKDEIQQNGQTIYLRGTGDFDLCRE---TIQPFMNKTNETQTSLNGVYQPPIHF 423
+D + E I GTGD LC+E +I F ++ S +GVYQP I
Sbjct: 306 SLCTVDQRPESYNPNDVITFEGTGDPSLCKEKVASIFDFKACHDQETCSFDGVYQPKI-- 363
Query: 424 QNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWS---ILRERFDRGLYASH 480
F F+ FYY T L + G ++ F + ++C+ WS +L +FD +YA
Sbjct: 364 -KGPFVAFAGFYY-TASALNLSGSFSLDTFNSSTWNFCSQNWSQLPLLLPKFDE-VYA-- 418
Query: 481 ADLHRLKYQCFKSAWMFEVFHRGFSF-PVNYKSLKTALQVYDKEVQWTLGAILYRTRFLP 539
+ CF + +++ +F G+ F + + +V + + W+LG +L T +P
Sbjct: 419 ------RSYCFSANYIYHLFVNGYKFTEETWPQIHFEKEVGNSSIAWSLGYMLSLTNQIP 472
>gi|45827718 ectonucleoside triphosphate diphosphohydrolase 2
isoform 1 [Homo sapiens]
Length = 495
Score = 142 bits (357), Expect = 1e-33
Identities = 127/466 (27%), Positives = 197/466 (42%), Gaps = 63/466 (13%)
Query: 85 PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144
P + YGIV+D GSS + +F+Y WP N ++ D GIS +A
Sbjct: 36 PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
Query: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204
+P S + L A + VP+ +H TPLY+ TAGMR+L + +A L+
Sbjct: 88 NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
Query: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264
+ F A ++SG++EGV+ W+ N++L F G RK
Sbjct: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
Query: 265 RTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVAT 324
T G +D+GG STQI +E T S A + EV +L + YRVY +
Sbjct: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQLHLYGQH------------YRVYTHS 239
Query: 325 FLGFGGNAARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379
FL +G R + R+ A+ +Q + G T + Y PC
Sbjct: 240 FLCYG----RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
Query: 380 NGQTIYLRGTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYC 437
+ + + L G+ D LCR+ + + ++ ++ S NGV+QPP+ F FS F+Y
Sbjct: 296 SAR-VSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY- 350
Query: 438 TEDVLRMGGDYNAA---KFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSA 494
T D LR A + AA + C W+ L+ R RL C +
Sbjct: 351 TVDFLRTSMGLPVATLQQLEAAAVNVCNQTWAQLQARVP-------GQRARLADYCAGAM 403
Query: 495 WMFEVFHRGFSFPVN-YKSLKTALQVYDKEVQWTLGAILYRTRFLP 539
++ ++ RG+ F + + + D V W LG +L T +P
Sbjct: 404 FVQQLLSRGYGFDERAFGGVIFQKKAADTAVGWALGYMLNLTNLIP 449
>gi|110431368 ectonucleoside triphosphate diphosphohydrolase 8
isoform 1 [Homo sapiens]
Length = 495
Score = 131 bits (329), Expect = 2e-30
Identities = 126/486 (25%), Positives = 207/486 (42%), Gaps = 85/486 (17%)
Query: 77 IEATDTNNP-NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKI 135
+EAT P ++ +GIV D GSS + +F+Y W + N ++ + + ++
Sbjct: 30 VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVS---------QALACQV 80
Query: 136 K-PGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQK--- 191
+ PGIS + ++ + + + L A +P A+H++TP ++ TAGMR+L
Sbjct: 81 EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
Query: 192 ---AILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVV 248
A + +L PV F AE+++G+ EG + WI +N+ LG +V
Sbjct: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLG----------TLV 184
Query: 249 EVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNL- 307
+ + G + G LDMGG STQI + + S+Q A+F L
Sbjct: 185 KYSFTGEWIQPP--EEMLVGALDMGGASTQITFVPGGPILDKSTQ---------ADFRLY 233
Query: 308 GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKN---------RLLGKQTGL 358
G D Y VY ++L FG R + R+ +Q L G QT L
Sbjct: 234 GSD-------YSVYTHSYLCFG----RDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTL 282
Query: 359 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN---ETQTSLNG 415
Y PC+ + QN + + GTG+ C I+ N ++ + + +G
Sbjct: 283 ALGPLYESPCVHATPPLSLPQN---LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDG 339
Query: 416 VYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRG 475
VYQPP+ +FY FS FYY T L + + ++C W ++
Sbjct: 340 VYQPPL---RGQFYAFSNFYY-TFHFLNLTSRQPLSTVNATIWEFCQRPWKLVE------ 389
Query: 476 LYASHADLHR-LKYQCFKSAWMFEVFHRGFSF-PVNYKSLKTALQVYDKEVQWTLGAILY 533
AS+ R L+ C ++ + H G+ F + SL+ Q ++ WTLG +L
Sbjct: 390 --ASYPGQDRWLRDYCASGLYILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLN 447
Query: 534 RTRFLP 539
T +P
Sbjct: 448 LTGMIP 453
>gi|4557421 ectonucleoside triphosphate diphosphohydrolase 2 isoform
2 [Homo sapiens]
Length = 472
Score = 130 bits (327), Expect = 4e-30
Identities = 111/392 (28%), Positives = 169/392 (43%), Gaps = 55/392 (14%)
Query: 85 PNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFAT 144
P + YGIV+D GSS + +F+Y WP N ++ D GIS +A
Sbjct: 36 PALKYGIVLDAGSSHTSMFIYKWPADKENDTGIVGQHSSCDVPGG--------GISSYAD 87
Query: 145 SPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVH 204
+P S + L A + VP+ +H TPLY+ TAGMR+L + +A L+
Sbjct: 88 NPSGASQSLVGCLEQALQDVPKERHAGTPLYLGATAGMRLLNLTNPEASTSVLMAVTHTL 147
Query: 205 FDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRK 264
+ F A ++SG++EGV+ W+ N++L F G RK
Sbjct: 148 TQYPFDFRGARILSGQEEGVFGWVTANYLLENFIKY-------------GWVGRWFRPRK 194
Query: 265 RTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVAT 324
T G +D+GG STQI +E T S A + EV +L + YRVY +
Sbjct: 195 GTLGAMDLGGASTQITFE---TTSPAEDRASEVQLHLYGQH------------YRVYTHS 239
Query: 325 FLGFGGNAARQRYEDRIFANTIQKNRL-----LGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379
FL +G R + R+ A+ +Q + G T + Y PC
Sbjct: 240 FLCYG----RDQVLQRLLASALQTHGFHPCWPRGFSTQVLLGDVYQSPCTMAQRPQNFNS 295
Query: 380 NGQTIYLRGTGDFDLCRETIQPFMNKTN--ETQTSLNGVYQPPIHFQNSEFYGFSEFYYC 437
+ + + L G+ D LCR+ + + ++ ++ S NGV+QPP+ F FS F+Y
Sbjct: 296 SAR-VSLSGSSDPHLCRDLVSGLFSFSSCPFSRCSFNGVFQPPV---AGNFVAFSAFFY- 350
Query: 438 TEDVLRMGGDYNAA---KFTKAAKDYCATKWS 466
T D LR A + AA + C W+
Sbjct: 351 TVDFLRTSMGLPVATLQQLEAAAVNVCNQTWA 382
>gi|4557427 ectonucleoside triphosphate diphosphohydrolase 5 [Homo
sapiens]
Length = 428
Score = 118 bits (295), Expect = 2e-26
Identities = 111/451 (24%), Positives = 180/451 (39%), Gaps = 86/451 (19%)
Query: 89 YGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGISEFATSPEK 148
YGI+ D GS+G+R+ VY + + +L+ V +KPG+S F P++
Sbjct: 49 YGIMFDAGSTGTRIHVYTFVQKMPGQLPILE---------GEVFDSVKPGLSAFVDQPKQ 99
Query: 149 VSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLTDIPVHFDFL 208
++ + LL A + +PR+ K+TP+ + TAG+R+LPE + KA+L + + +I FL
Sbjct: 100 GAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFE-VKEIFRKSPFL 158
Query: 209 FSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAG 268
++ G EG+ AW+ +NF+ G+ R+ T G
Sbjct: 159 VPKGSVSIMDGSDEGILAWVTVNFLTGQLHG----------------------HRQETVG 196
Query: 269 ILDMGGVSTQIAY--EVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFL 326
LD+GG STQI + + KT+ E+ + L F + Y++Y ++L
Sbjct: 197 TLDLGGASTQITFLPQFEKTL-------EQTPRGYLTSFEM------FNSTYKLYTHSYL 243
Query: 327 GFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQNGQTIYL 386
GFG AAR L +T T + CLP ++ E G
Sbjct: 244 GFGLKAARLA-------------TLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQY 290
Query: 387 RGTGDFDLCRETIQPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEFYYCTEDV----L 442
G + ++ E E + G P Q FY FS +Y D
Sbjct: 291 GGNQEGEVGFEPCYA------EVLRVVRGKLHQPEEVQRGSFYAFSYYYDRAVDTDMIDY 344
Query: 443 RMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQCFKSAWMFEVFHR 502
GG F + A++ C E F G + C +++ +
Sbjct: 345 EKGGILKVEDFERKAREVCDN-----LENFTSG----------SPFLCMDLSYITALLKD 389
Query: 503 GFSFPVNYKSLKTALQVYDKEVQWTLGAILY 533
GF F + L+ +V + E W LGA +
Sbjct: 390 GFGF-ADSTVLQLTKKVNNIETGWALGATFH 419
>gi|110431366 ectonucleoside triphosphate diphosphohydrolase 8
isoform 2 [Homo sapiens]
Length = 458
Score = 108 bits (269), Expect = 2e-23
Identities = 122/485 (25%), Positives = 198/485 (40%), Gaps = 120/485 (24%)
Query: 77 IEATDTNNP-NVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKI 135
+EAT P ++ +GIV D GSS + +F+Y W + N ++ + + ++
Sbjct: 30 VEATSVLLPTDIKFGIVFDAGSSHTSLFLYQWLANKENGTGVVS---------QALACQV 80
Query: 136 K-PGISEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQK--- 191
+ PGIS + ++ + + + L A +P A+H++TP ++ TAGMR+L
Sbjct: 81 EGPGISSYTSNAAQAGESLQGCLEEALVLIPEAQHRKTPTFLGATAGMRLLSRKNSSQAR 140
Query: 192 ---AILEDLLTDIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVV 248
A + +L PV F AE+++G+ EG + WI +N+ LG +V
Sbjct: 141 DIFAAVTQVLGRSPVDF------WGAELLAGQAEGAFGWITVNYGLG----------TLV 184
Query: 249 EVNIPGSESSEAIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNL- 307
+ + G + G LDMGG STQI + + S+Q A+F L
Sbjct: 185 KYSFTGEWIQPP--EEMLVGALDMGGASTQITFVPGGPILDKSTQ---------ADFRLY 233
Query: 308 GCDVHQTEHVYRVYVATFLGFGGNAARQRYEDRIFANTIQKN---------RLLGKQTGL 358
G D Y VY ++L FG R + R+ +Q L G QT L
Sbjct: 234 GSD-------YSVYTHSYLCFG----RDQMLSRLLVGLVQSRPAALLRHPCYLSGYQTTL 282
Query: 359 TPDMPYLDPCLPLDIKDEIQQNGQTIYLRGTGDFDLCRETIQPFMNKTN---ETQTSLNG 415
Y PC+ + QN + + GTG+ C I+ N ++ + + +G
Sbjct: 283 ALGPLYESPCVHATPPLSLPQN---LTVEGTGNPGACVSAIRELFNFSSCQGQEDCAFDG 339
Query: 416 VYQPPIHFQNSEFYGFSEFYYCTEDVLRMGGDYNAAKFTKAAKDYCATKWSILRERFDRG 475
VYQPP+ +FY E Y +D + +DYCA+ G
Sbjct: 340 VYQPPL---RGQFY--VEASYPGQD--------------RWLRDYCAS-----------G 369
Query: 476 LYASHADLHRLKYQCFKSAWMFEVFHRGFSF-PVNYKSLKTALQVYDKEVQWTLGAILYR 534
LY + + H G+ F + SL+ Q ++ WTLG +L
Sbjct: 370 LY------------------ILTLLHEGYGFSEETWPSLEFRKQAGGVDIGWTLGYMLNL 411
Query: 535 TRFLP 539
T +P
Sbjct: 412 TGMIP 416
>gi|166235895 ectonucleoside triphosphate diphosphohydrolase 6
isoform 2 [Homo sapiens]
Length = 467
Score = 102 bits (253), Expect = 1e-21
Identities = 115/463 (24%), Positives = 181/463 (39%), Gaps = 93/463 (20%)
Query: 80 TDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGI 139
T + V YGI+ D GS+G+RV V+ + R P + + K +KPG+
Sbjct: 76 TAADGHEVFYGIMFDAGSTGTRVHVFQFTRP---PRETPTLTHETFK-------ALKPGL 125
Query: 140 SEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLT 199
S +A EK + I LL+ A + +P K TPL + TAG+R+LP + + +L+ +
Sbjct: 126 SAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQK-VK 184
Query: 200 DIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSE 259
++ FL D +++G EGV AWI INF+ G + PG S
Sbjct: 185 EVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTG-------------SLKTPGGSS-- 229
Query: 260 AIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYR 319
G+LD+GG STQIA+ +P+ + L FN Y+
Sbjct: 230 -------VGMLDLGGGSTQIAF-LPRVEGTLQASPPGYL-TALRMFN---------RTYK 271
Query: 320 VYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379
+Y ++LG G +AR + + + L + PCL K E +
Sbjct: 272 LYSYSYLGLGLMSARLAILGGVEGQPAKDGKEL------------VSPCLSPSFKGEWEH 319
Query: 380 NGQTIYLRG----TGDFDLCRETI-QPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEF 434
T + G +LC + + N+ + T+ ++ +FY FS +
Sbjct: 320 AEVTYRVSGQKAAASLHELCAARVSEVLQNRVHRTE-----------EVKHVDFYAFSYY 368
Query: 435 YYCTEDV----LRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQC 490
Y V GG F AAK C T + C
Sbjct: 369 YDLAAGVGLIDAEKGGSLVVGDFEIAAKYVCRT---------------LETQPQSSPFSC 413
Query: 491 FKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILY 533
++ + + F FP K LK ++ + E W LGAI +
Sbjct: 414 MDLTYV-SLLLQEFGFP-RSKVLKLTRKIDNVETSWALGAIFH 454
>gi|166235893 ectonucleoside triphosphate diphosphohydrolase 6
isoform 1 [Homo sapiens]
Length = 484
Score = 102 bits (253), Expect = 1e-21
Identities = 115/463 (24%), Positives = 181/463 (39%), Gaps = 93/463 (20%)
Query: 80 TDTNNPNVNYGIVVDCGSSGSRVFVYCWPRHNGNPHDLLDIRQMRDKNRKPVVMKIKPGI 139
T + V YGI+ D GS+G+RV V+ + R P + + K +KPG+
Sbjct: 93 TAADGHEVFYGIMFDAGSTGTRVHVFQFTRP---PRETPTLTHETFK-------ALKPGL 142
Query: 140 SEFATSPEKVSDYISPLLNFAAEHVPRAKHKETPLYILCTAGMRILPESQQKAILEDLLT 199
S +A EK + I LL+ A + +P K TPL + TAG+R+LP + + +L+ +
Sbjct: 143 SAYADDVEKSAQGIRELLDVAKQDIPFDFWKATPLVLKATAGLRLLPGEKAQKLLQK-VK 201
Query: 200 DIPVHFDFLFSDSHAEVISGKQEGVYAWIGINFVLGRFEHIEDDDEAVVEVNIPGSESSE 259
++ FL D +++G EGV AWI INF+ G + PG S
Sbjct: 202 EVFKASPFLVGDDCVSIMNGTDEGVSAWITINFLTG-------------SLKTPGGSS-- 246
Query: 260 AIVRKRTAGILDMGGVSTQIAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYR 319
G+LD+GG STQIA+ +P+ + L FN Y+
Sbjct: 247 -------VGMLDLGGGSTQIAF-LPRVEGTLQASPPGYL-TALRMFN---------RTYK 288
Query: 320 VYVATFLGFGGNAARQRYEDRIFANTIQKNRLLGKQTGLTPDMPYLDPCLPLDIKDEIQQ 379
+Y ++LG G +AR + + + L + PCL K E +
Sbjct: 289 LYSYSYLGLGLMSARLAILGGVEGQPAKDGKEL------------VSPCLSPSFKGEWEH 336
Query: 380 NGQTIYLRG----TGDFDLCRETI-QPFMNKTNETQTSLNGVYQPPIHFQNSEFYGFSEF 434
T + G +LC + + N+ + T+ ++ +FY FS +
Sbjct: 337 AEVTYRVSGQKAAASLHELCAARVSEVLQNRVHRTE-----------EVKHVDFYAFSYY 385
Query: 435 YYCTEDV----LRMGGDYNAAKFTKAAKDYCATKWSILRERFDRGLYASHADLHRLKYQC 490
Y V GG F AAK C T + C
Sbjct: 386 YDLAAGVGLIDAEKGGSLVVGDFEIAAKYVCRT---------------LETQPQSSPFSC 430
Query: 491 FKSAWMFEVFHRGFSFPVNYKSLKTALQVYDKEVQWTLGAILY 533
++ + + F FP K LK ++ + E W LGAI +
Sbjct: 431 MDLTYV-SLLLQEFGFP-RSKVLKLTRKIDNVETSWALGAIFH 471
>gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens]
Length = 459
Score = 29.6 bits (65), Expect = 8.6
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 20/147 (13%)
Query: 220 KQEGVYAWIGINFVLG-RFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQ 278
+Q+ WI + VL + E IEDD +V E + S +S A K+ + I GV
Sbjct: 162 QQDANECWIQMMRVLQQKLEAIEDD--SVKETD--SSSASAATPSKKKSLIDQFFGV--- 214
Query: 279 IAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYE 338
E T+ S++EEV K + L C ++Q F G R + E
Sbjct: 215 ---EFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL---------FTGLKLRLQEE 262
Query: 339 DRIFANTIQKNRLLGKQTGLTPDMPYL 365
+ T+Q+N L K + ++ YL
Sbjct: 263 ITKQSPTLQRNALYIKSSKISRLPAYL 289
>gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens]
Length = 494
Score = 29.6 bits (65), Expect = 8.6
Identities = 40/147 (27%), Positives = 62/147 (42%), Gaps = 20/147 (13%)
Query: 220 KQEGVYAWIGINFVLG-RFEHIEDDDEAVVEVNIPGSESSEAIVRKRTAGILDMGGVSTQ 278
+Q+ WI + VL + E IEDD +V E + S +S A K+ + I GV
Sbjct: 197 QQDANECWIQMMRVLQQKLEAIEDD--SVKETD--SSSASAATPSKKKSLIDQFFGV--- 249
Query: 279 IAYEVPKTVSFASSQQEEVAKNLLAEFNLGCDVHQTEHVYRVYVATFLGFGGNAARQRYE 338
E T+ S++EEV K + L C ++Q F G R + E
Sbjct: 250 ---EFETTMKCTESEEEEVTKGKENQLQLSCFINQEVKYL---------FTGLKLRLQEE 297
Query: 339 DRIFANTIQKNRLLGKQTGLTPDMPYL 365
+ T+Q+N L K + ++ YL
Sbjct: 298 ITKQSPTLQRNALYIKSSKISRLPAYL 324
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.424
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,749,926
Number of Sequences: 37866
Number of extensions: 972243
Number of successful extensions: 1933
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1868
Number of HSP's gapped (non-prelim): 17
length of query: 616
length of database: 18,247,518
effective HSP length: 108
effective length of query: 508
effective length of database: 14,157,990
effective search space: 7192258920
effective search space used: 7192258920
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.