Guide to the Human Genome
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Search of human proteins with 47519953

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
member 4 [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47519953 leukocyte immunoglobulin-like receptor subfamily A m...  1031   0.0  
gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A...   672   0.0  
gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B...   624   e-179
gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B...   624   e-179
gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A (...   620   e-178
gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A...   597   e-171
gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A (...   573   e-164
gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A ...   552   e-157
gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B...   541   e-154
gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B...   538   e-153
gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B...   530   e-150
gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B...   530   e-150
gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B...   530   e-150
gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B...   530   e-150
gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B, ...   523   e-148
gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B...   521   e-148
gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B...   340   1e-93
gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like...   276   3e-74
gi|32895361 leukocyte immunoglobulin-like receptor subfamily A m...   271   8e-73
gi|32490553 leukocyte immunoglobulin-like receptor subfamily A m...   268   7e-72
gi|32895365 leukocyte immunoglobulin-like receptor subfamily A m...   249   5e-66
gi|32895363 leukocyte immunoglobulin-like receptor subfamily A m...   246   5e-65
gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B...   241   1e-63
gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B...   241   1e-63
gi|134268642 killer cell immunoglobulin-like receptor, three dom...   229   4e-60
gi|134268644 killer cell immunoglobulin-like receptor, three dom...   225   8e-59
gi|46488946 killer cell immunoglobulin-like receptor, three doma...   219   6e-57
gi|134133244 killer cell immunoglobulin-like receptor, three dom...   216   4e-56
gi|62632748 killer-cell Ig-like receptor [Homo sapiens]               203   3e-52
gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo...   178   1e-44

>gi|47519953 leukocyte immunoglobulin-like receptor subfamily A
           member 4 [Homo sapiens]
          Length = 499

 Score = 1031 bits (2666), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL
Sbjct: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY 120
           DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY
Sbjct: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY 120

Query: 121 SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALF 180
           SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALF
Sbjct: 121 SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALF 180

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
           PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL
Sbjct: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHN 300
           TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHN
Sbjct: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHN 300

Query: 301 VSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGA 360
           VSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGA
Sbjct: 301 VSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGA 360

Query: 361 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGA 420
           AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGA
Sbjct: 361 AHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGA 420

Query: 421 TETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQE 480
           TETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQE
Sbjct: 421 TETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSPPRCSQE 480

Query: 481 ANSRKDNAPFRVVEPWEQI 499
           ANSRKDNAPFRVVEPWEQI
Sbjct: 481 ANSRKDNAPFRVVEPWEQI 499


>gi|110611910 leukocyte immunoglobulin-like receptor, subfamily A,
           member 6 [Homo sapiens]
          Length = 481

 Score =  672 bits (1733), Expect = 0.0
 Identities = 340/475 (71%), Positives = 382/475 (80%), Gaps = 1/475 (0%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT  LT+LL  GLSLGPRTRVQA   PKP LWAEPG VI+W +PVTIWCQG+LEAQ Y+L
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSLEAQEYQL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA- 119
           DKEG+         LE +NK + SIPSM   HAGRY C+Y S AGWSEPSDPLELV+T  
Sbjct: 61  DKEGSPEPLDRNNPLEPKNKARFSIPSMTQHHAGRYRCHYYSSAGWSEPSDPLELVMTGF 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           Y++PTLSALPSPVV SG N+TLRC S+ G   F L++EG+H+L  TL+S Q + G FQAL
Sbjct: 121 YNKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSGGFQAL 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           FP+GP+T S+R  F CY Y  NTP VWS PSDPL++L SGVSRKPSLLTLQGPV+ PG++
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPRVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQCGSDVGY R+ LYKEG     QRPG+QPQAGLSQANFTL PVS S+GGQYRCYGAH
Sbjct: 241 LTLQCGSDVGYDRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSHGGQYRCYGAH 300

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSEWSAPSDPL+IL+AGQI D  SLS QPGPTV SGE VTLLCQS     TFLLTKEG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSRGYFDTFLLTKEG 360

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS SSNP+LLS PSEPLEL+VSG
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSFPSEPLELMVSG 420

Query: 420 ATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSP 474
            +   +       S  A H +DYTVENLIRMG+AGLVL+FLGILLFEAQHSQR+P
Sbjct: 421 HSGGSSLPPTGPPSTPASHAKDYTVENLIRMGMAGLVLVFLGILLFEAQHSQRNP 475


>gi|125661043 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 1 [Homo sapiens]
          Length = 632

 Score =  624 bits (1609), Expect = e-179
 Identities = 327/476 (68%), Positives = 370/476 (77%), Gaps = 10/476 (2%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT  LT+LL  GLSLGPRTRVQA   PKP LWAEPG VI+W +PVTIWCQG+ EAQ YRL
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            KEG+         LE +NK + SIPSM   HAGRY C+Y S AGWSEPSDPLE+V+T A
Sbjct: 61  HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           YS+PTLSALPSPVV SG N+TLRC S+ G   F L++EG+H+L  TL+S Q +   FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           FP+GP+T S+R  F CY Y  NTP+VWS PSDPL++L SGVSRKPSLLTLQGPV+ PG++
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQCGSDVGY R+ LYKEG     QRPG+QPQAGLSQANFTL PVS S GGQYRCYGAH
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSEWSAPSDPL+IL+AGQI D  SLS QPGPTV SGE VTLLCQSW    TFLLTKEG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS SSNP+LLSHPSEPLELVVSG
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSG 420

Query: 420 AT--ETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLF--LGILLFEAQHSQ 471
            +   +L P    S     P L  Y +E LI + VA ++LLF  L +LL   +HS+
Sbjct: 421 HSGGSSLPPTGPPS----TPGLGRY-LEVLIGVSVAFVLLLFLLLFLLLRRQRHSK 471


>gi|125661045 leukocyte immunoglobulin-like receptor, subfamily B,
           member 3 isoform 2 [Homo sapiens]
          Length = 631

 Score =  624 bits (1609), Expect = e-179
 Identities = 327/476 (68%), Positives = 370/476 (77%), Gaps = 10/476 (2%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT  LT+LL  GLSLGPRTRVQA   PKP LWAEPG VI+W +PVTIWCQG+ EAQ YRL
Sbjct: 1   MTPALTALLCLGLSLGPRTRVQAGPFPKPTLWAEPGSVISWGSPVTIWCQGSQEAQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            KEG+         LE +NK + SIPSM   HAGRY C+Y S AGWSEPSDPLE+V+T A
Sbjct: 61  HKEGSPEPLDRNNPLEPKNKARFSIPSMTEHHAGRYRCHYYSSAGWSEPSDPLEMVMTGA 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           YS+PTLSALPSPVV SG N+TLRC S+ G   F L++EG+H+L  TL+S Q +   FQAL
Sbjct: 121 YSKPTLSALPSPVVASGGNMTLRCGSQKGYHHFVLMKEGEHQLPRTLDSQQLHSRGFQAL 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           FP+GP+T S+R  F CY Y  NTP+VWS PSDPL++L SGVSRKPSLLTLQGPV+ PG++
Sbjct: 181 FPVGPVTPSHRWRFTCYYYYTNTPWVWSHPSDPLEILPSGVSRKPSLLTLQGPVLAPGQS 240

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQCGSDVGY R+ LYKEG     QRPG+QPQAGLSQANFTL PVS S GGQYRCYGAH
Sbjct: 241 LTLQCGSDVGYNRFVLYKEGERDFLQRPGQQPQAGLSQANFTLGPVSPSNGGQYRCYGAH 300

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSEWSAPSDPL+IL+AGQI D  SLS QPGPTV SGE VTLLCQSW    TFLLTKEG
Sbjct: 301 NLSSEWSAPSDPLNILMAGQIYDTVSLSAQPGPTVASGENVTLLCQSWWQFDTFLLTKEG 360

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGS SSNP+LLSHPSEPLELVVSG
Sbjct: 361 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSYSSNPHLLSHPSEPLELVVSG 420

Query: 420 AT--ETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLF--LGILLFEAQHSQ 471
            +   +L P    S     P L  Y +E LI + VA ++LLF  L +LL   +HS+
Sbjct: 421 HSGGSSLPPTGPPS----TPGLGRY-LEVLIGVSVAFVLLLFLLLFLLLRRQRHSK 471


>gi|5803066 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 1 [Homo sapiens]
          Length = 489

 Score =  620 bits (1600), Expect = e-178
 Identities = 323/488 (66%), Positives = 364/488 (74%), Gaps = 15/488 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT I+T L+   LSLGPRT VQA  LPKP LWAEPG VIT  +PVT+WCQG LE Q YRL
Sbjct: 1   MTPIVTVLICLRLSLGPRTHVQAGTLPKPTLWAEPGSVITQGSPVTLWCQGILETQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQS-PAGWSEPSDPLELVVT- 118
            +E  +         E   K +  IPS+ WEH GRY C+Y S  AGWSEPSDPLELVVT 
Sbjct: 61  YREKKTAPWITRIPQEIVKKGQFPIPSITWEHTGRYRCFYGSHTAGWSEPSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AY +PTLSALPSPVVTSG NVTL C S++  G F L +EG+      LNS    HG  +A
Sbjct: 121 AYIKPTLSALPSPVVTSGGNVTLHCVSQVAFGSFILCKEGEDEHPQCLNSQPRTHGWSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R ++RCY Y++N+P+VWS PSD L+LLV GVS+KPSL    GP+V PGE
Sbjct: 181 IFSVGPVSPSRRWSYRCYAYDSNSPHVWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPGE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
           +LTLQC SDV Y R+ LYKEG     Q PG QPQAGLSQANFTL PVSRSYGGQYRC GA
Sbjct: 241 SLTLQCVSDVSYDRFVLYKEGERDFLQLPGPQPQAGLSQANFTLGPVSRSYGGQYRCSGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           +N+SSEWSAPSDPLDILIAGQ   RP +SV PGPTV SGE VTLLCQSW P  TFLLTK 
Sbjct: 301 YNLSSEWSAPSDPLDILIAGQFRGRPFISVHPGPTVASGENVTLLCQSWGPFHTFLLTKA 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  PLRLRS++   KYQAEFPMSPVTSAH+GTYRCYGS SSNPYLLSHPS+ LEL+VS
Sbjct: 361 GAADAPLRLRSIHEYPKYQAEFPMSPVTSAHSGTYRCYGSLSSNPYLLSHPSDSLELMVS 420

Query: 419 GATETLNPAQKKSDS-------------KTAPHLQDYTVENLIRMGVAGLVLLFLGILLF 465
           GA ETL+P Q KSDS             KTA H QDYTVENLIRMG+AGLVL+ LGILLF
Sbjct: 421 GAAETLSPPQNKSDSKAGAANTLSPSQNKTASHPQDYTVENLIRMGIAGLVLVVLGILLF 480

Query: 466 EAQHSQRS 473
           EAQHSQRS
Sbjct: 481 EAQHSQRS 488


>gi|195972797 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform a [Homo sapiens]
          Length = 483

 Score =  597 bits (1539), Expect = e-171
 Identities = 315/477 (66%), Positives = 357/477 (74%), Gaps = 5/477 (1%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VI   +PVT+ CQG+L+A+ Y L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            +E  S S  + +  E     +  IPS+ WEHAGRYHC Y S    SE SDPLELVVT A
Sbjct: 61  YRENKSAS-WVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           YS+PTLSALPSPVVT G NVTL+C S++    F L +EG+      LNSH H  G   A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           F +GP++ S R ++RCY Y++N+PYVWS PSD L+LLV GVS+KPSL    GP+V PGE+
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY R+ LYKEG     QRPG QPQAGLSQANFTL PVS S+GGQYRCY AH
Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSEWSAPSDPLDILI GQ  DRPSLSVQP PTV  G+ VTLLCQS     TFLLTKEG
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           A HPPL LRS + A + QAEF M PVTSAH GTYRCY S SSNPYLLS PS+PLELVVS 
Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVSE 419

Query: 420 ATETLNPAQKKSDSKT---APHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRS 473
           A ETL+P+Q K+DS T     H QDYTVENLIRMGVAGLVL+ LGILLFEAQHSQRS
Sbjct: 420 AAETLSPSQNKTDSTTTSLGQHPQDYTVENLIRMGVAGLVLVVLGILLFEAQHSQRS 476


>gi|5803068 leukocyte immunoglobulin-like receptor, subfamily A
           (with TM domain), member 2 isoform b [Homo sapiens]
          Length = 466

 Score =  573 bits (1478), Expect = e-164
 Identities = 305/474 (64%), Positives = 345/474 (72%), Gaps = 16/474 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VI   +PVT+ CQG+L+A+ Y L
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVIIQGSPVTLRCQGSLQAEEYHL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            +E  S S  + +  E     +  IPS+ WEHAGRYHC Y S    SE SDPLELVVT A
Sbjct: 61  YRENKSAS-WVRRIQEPGKNGQFPIPSITWEHAGRYHCQYYSHNHSSEYSDPLELVVTGA 119

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           YS+PTLSALPSPVVT G NVTL+C S++    F L +EG+      LNSH H  G   A+
Sbjct: 120 YSKPTLSALPSPVVTLGGNVTLQCVSQVAFDGFILCKEGEDEHPQRLNSHSHARGWSWAI 179

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           F +GP++ S R ++RCY Y++N+PYVWS PSD L+LLV GVS+KPSL    GP+V PGE+
Sbjct: 180 FSVGPVSPSRRWSYRCYAYDSNSPYVWSLPSDLLELLVPGVSKKPSLSVQPGPMVAPGES 239

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY R+ LYKEG     QRPG QPQAGLSQANFTL PVS S+GGQYRCY AH
Sbjct: 240 LTLQCVSDVGYDRFVLYKEGERDFLQRPGWQPQAGLSQANFTLGPVSPSHGGQYRCYSAH 299

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSEWSAPSDPLDILI GQ  DRPSLSVQP PTV  G+ VTLLCQS     TFLLTKEG
Sbjct: 300 NLSSEWSAPSDPLDILITGQFYDRPSLSVQPVPTVAPGKNVTLLCQSRGQFHTFLLTKEG 359

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           A HPPL LRS + A + QAEF M PVTSAH GTYRCY S SSNPYLLS PS+PLELVVS 
Sbjct: 360 AGHPPLHLRSEHQAQQNQAEFRMGPVTSAHVGTYRCYSSLSSNPYLLSLPSDPLELVVS- 418

Query: 420 ATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRS 473
                        +    H QDYTVENLIRMGVAGLVL+ LGILLFEAQHSQRS
Sbjct: 419 -------------ASLGQHPQDYTVENLIRMGVAGLVLVVLGILLFEAQHSQRS 459


>gi|31543056 leukocyte immunoglobulin-like receptor, subfamily A
           (without TM domain), member 3 [Homo sapiens]
          Length = 439

 Score =  552 bits (1423), Expect = e-157
 Identities = 290/436 (66%), Positives = 324/436 (74%), Gaps = 2/436 (0%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSL PRT VQA  LPKP LWAEPG VIT  +PVT+ CQG+LE Q Y L
Sbjct: 1   MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQS-PAGWSEPSDPLELVVT- 118
            +E  +         E   K +  I S+ WEHAGRY C Y S   G SE SDPLELVVT 
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTVGLSESSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AYS+PTLSALPSPVVTSG NVT++C S++    F L +EG+      LNSH H  G  +A
Sbjct: 121 AYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R ++RCYGY++  PYVWS PSD L LLV GVS+KPSL    GPVV PGE
Sbjct: 181 IFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
            LT QCGSD GY R+ LYKE      QRPGRQPQAGLSQANFTL PVSRSYGGQY C GA
Sbjct: 241 KLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAGLSQANFTLGPVSRSYGGQYTCSGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           +N+SSEWSAPSDPLDILI GQI  RP LSV+PGPTV SGE VTLLCQS   M TFLLTKE
Sbjct: 301 YNLSSEWSAPSDPLDILITGQIRARPFLSVRPGPTVASGENVTLLCQSQGGMHTFLLTKE 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  PLRL+S   +HKYQAEFPMSPVTSAHAGTYRCYGS SSNPYLL+HPS+PLELVVS
Sbjct: 361 GAADSPLRLKSKRQSHKYQAEFPMSPVTSAHAGTYRCYGSLSSNPYLLTHPSDPLELVVS 420

Query: 419 GATETLNPAQKKSDSK 434
           GA ETL+P Q KSDSK
Sbjct: 421 GAAETLSPPQNKSDSK 436


>gi|125988398 leukocyte immunoglobulin-like receptor, subfamily B,
           member 2 isoform 2 [Homo sapiens]
          Length = 597

 Score =  541 bits (1393), Expect = e-154
 Identities = 292/479 (60%), Positives = 334/479 (69%), Gaps = 14/479 (2%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT I+T L+  GLSLGPRT VQ   +PKP LWAEP  VIT  +PVT+ CQG+LEAQ YRL
Sbjct: 1   MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            +E  S S       E     +  IPS+ WEH GRY C Y S A WSE SDPL LV+T A
Sbjct: 61  YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           Y +PTLSA PSPVVTSG  VTL+C S++  G F L +EG+      LNS  H  G  +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           F +GP++ + R + RCYGY+ N+PYVWS PSD L+LLV GVS+KPSL    GPVV PGE+
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGES 240

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY R+ LYKEG   L Q PGRQPQAGLSQANFTL PVSRSYGGQYRCYGAH
Sbjct: 241 LTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAH 300

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSE SAPSDPLDILI GQI   P +SVQPGPTV SGE VTLLCQSW    TFLLTK G
Sbjct: 301 NLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAG 360

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AA  PLRLRS++   KYQAEFPMSPVTSAHAGTYRCYGS +S+PYLLSHPSEPLELVVSG
Sbjct: 361 AADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG 420

Query: 420 ATETLNPAQKKSDSKTAPHLQDYTVEN-------------LIRMGVAGLVLLFLGILLF 465
            +   +P      S   P  Q  T                +I + VA ++LL L +LLF
Sbjct: 421 PSMGSSPPPTGPISTPGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVVLLLLLLLLLF 479


>gi|125988400 leukocyte immunoglobulin-like receptor, subfamily B,
           member 2 isoform 1 [Homo sapiens]
          Length = 598

 Score =  538 bits (1385), Expect = e-153
 Identities = 279/427 (65%), Positives = 316/427 (74%), Gaps = 1/427 (0%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT I+T L+  GLSLGPRT VQ   +PKP LWAEP  VIT  +PVT+ CQG+LEAQ YRL
Sbjct: 1   MTPIVTVLICLGLSLGPRTHVQTGTIPKPTLWAEPDSVITQGSPVTLSCQGSLEAQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-A 119
            +E  S S       E     +  IPS+ WEH GRY C Y S A WSE SDPL LV+T A
Sbjct: 61  YREKKSASWITRIRPELVKNGQFHIPSITWEHTGRYGCQYYSRARWSELSDPLVLVMTGA 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           Y +PTLSA PSPVVTSG  VTL+C S++  G F L +EG+      LNS  H  G  +A+
Sbjct: 121 YPKPTLSAQPSPVVTSGGRVTLQCESQVAFGGFILCKEGEEEHPQCLNSQPHARGSSRAI 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           F +GP++ + R + RCYGY+ N+PYVWS PSD L+LLV GVS+KPSL    GPVV PGE+
Sbjct: 181 FSVGPVSPNRRWSHRCYGYDLNSPYVWSSPSDLLELLVPGVSKKPSLSVQPGPVVAPGES 240

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY R+ LYKEG   L Q PGRQPQAGLSQANFTL PVSRSYGGQYRCYGAH
Sbjct: 241 LTLQCVSDVGYDRFVLYKEGERDLRQLPGRQPQAGLSQANFTLGPVSRSYGGQYRCYGAH 300

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+SSE SAPSDPLDILI GQI   P +SVQPGPTV SGE VTLLCQSW    TFLLTK G
Sbjct: 301 NLSSECSAPSDPLDILITGQIRGTPFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAG 360

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AA  PLRLRS++   KYQAEFPMSPVTSAHAGTYRCYGS +S+PYLLSHPSEPLELVVSG
Sbjct: 361 AADAPLRLRSIHEYPKYQAEFPMSPVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVVSG 420

Query: 420 ATETLNP 426
            +   +P
Sbjct: 421 PSMGSSP 427



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 34/108 (31%), Positives = 51/108 (47%), Gaps = 8/108 (7%)

Query: 29  PILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIPS- 87
           P +  +PGP +     VT+ CQ   +   + L K G + +   L+++    K +   P  
Sbjct: 325 PFISVQPGPTVASGENVTLLCQSWRQFHTFLLTKAGAADAPLRLRSIHEYPKYQAEFPMS 384

Query: 88  -MMWEHAGRYHCY---YQSPAGWSEPSDPLELVVTAYSRPTLSALPSP 131
            +   HAG Y CY      P   S PS+PLELVV   S P++ + P P
Sbjct: 385 PVTSAHAGTYRCYGSLNSDPYLLSHPSEPLELVV---SGPSMGSSPPP 429


>gi|126362957 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 4 [Homo sapiens]
          Length = 651

 Score =  530 bits (1365), Expect = e-150
 Identities = 290/480 (60%), Positives = 332/480 (69%), Gaps = 15/480 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VIT  +PVT+ CQG  E Q YRL
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSP-AGWSEPSDPLELVVT- 118
            +E  +         E   K +  IPS+ WEHAGRY CYY S  AG SE SDPLELVVT 
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AY +PTLSA PSPVV SG NV L+C S++    F+L +EG+      LNS  H  G  +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R  +RCY Y++N+PY WS PSD L+LLV GVS+KPSL    GP+V P E
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
            LTLQCGSD GY R+ LYK+G     Q  G QPQAGLSQANFTL PVSRSYGGQYRCYGA
Sbjct: 241 TLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           HN+SSEWSAPSDPLDILIAGQ  DR SLSVQPGPTV SGE VTLLCQS   M TFLLTKE
Sbjct: 301 HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  P RLRS Y + KYQAEFPM PVTSAHAGTYRCYGS+SS PYLL+HPS+PLELVVS
Sbjct: 361 GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVS 420

Query: 419 GATETLNPAQKKSDSKTAPHLQDYTVEN-------------LIRMGVAGLVLLFLGILLF 465
           G +   +       S + P  Q  T                +I + VA ++LL L +LLF
Sbjct: 421 GPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLF 480


>gi|116488411 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 1 [Homo sapiens]
          Length = 650

 Score =  530 bits (1365), Expect = e-150
 Identities = 290/480 (60%), Positives = 332/480 (69%), Gaps = 15/480 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VIT  +PVT+ CQG  E Q YRL
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSP-AGWSEPSDPLELVVT- 118
            +E  +         E   K +  IPS+ WEHAGRY CYY S  AG SE SDPLELVVT 
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AY +PTLSA PSPVV SG NV L+C S++    F+L +EG+      LNS  H  G  +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R  +RCY Y++N+PY WS PSD L+LLV GVS+KPSL    GP+V P E
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
            LTLQCGSD GY R+ LYK+G     Q  G QPQAGLSQANFTL PVSRSYGGQYRCYGA
Sbjct: 241 TLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           HN+SSEWSAPSDPLDILIAGQ  DR SLSVQPGPTV SGE VTLLCQS   M TFLLTKE
Sbjct: 301 HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  P RLRS Y + KYQAEFPM PVTSAHAGTYRCYGS+SS PYLL+HPS+PLELVVS
Sbjct: 361 GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVS 420

Query: 419 GATETLNPAQKKSDSKTAPHLQDYTVEN-------------LIRMGVAGLVLLFLGILLF 465
           G +   +       S + P  Q  T                +I + VA ++LL L +LLF
Sbjct: 421 GPSGGPSSPTTGPTSTSGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLLF 480


>gi|126362953 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 3 [Homo sapiens]
          Length = 651

 Score =  530 bits (1364), Expect = e-150
 Identities = 290/481 (60%), Positives = 333/481 (69%), Gaps = 16/481 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VIT  +PVT+ CQG  E Q YRL
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSP-AGWSEPSDPLELVVT- 118
            +E  +         E   K +  IPS+ WEHAGRY CYY S  AG SE SDPLELVVT 
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AY +PTLSA PSPVV SG NV L+C S++    F+L +EG+      LNS  H  G  +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R  +RCY Y++N+PY WS PSD L+LLV GVS+KPSL    GP+V P E
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
            LTLQCGSD GY R+ LYK+G     Q  G QPQAGLSQANFTL PVSRSYGGQYRCYGA
Sbjct: 241 TLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           HN+SSEWSAPSDPLDILIAGQ  DR SLSVQPGPTV SGE VTLLCQS   M TFLLTKE
Sbjct: 301 HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  P RLRS Y + KYQAEFPM PVTSAHAGTYRCYGS+SS PYLL+HPS+PLELVVS
Sbjct: 361 GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVS 420

Query: 419 GAT-ETLNPAQKKSDSKTAPHLQDYTVEN-------------LIRMGVAGLVLLFLGILL 464
           G +    +P    + +   P  Q  T                +I + VA ++LL L +LL
Sbjct: 421 GPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLL 480

Query: 465 F 465
           F
Sbjct: 481 F 481


>gi|126362951 leukocyte immunoglobulin-like receptor, subfamily B,
           member 1 isoform 2 [Homo sapiens]
          Length = 652

 Score =  530 bits (1364), Expect = e-150
 Identities = 290/481 (60%), Positives = 333/481 (69%), Gaps = 16/481 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSLGPRT VQA +LPKP LWAEPG VIT  +PVT+ CQG  E Q YRL
Sbjct: 1   MTPILTVLICLGLSLGPRTHVQAGHLPKPTLWAEPGSVITQGSPVTLRCQGGQETQEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSP-AGWSEPSDPLELVVT- 118
            +E  +         E   K +  IPS+ WEHAGRY CYY S  AG SE SDPLELVVT 
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPIPSITWEHAGRYRCYYGSDTAGRSESSDPLELVVTG 120

Query: 119 AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQA 178
           AY +PTLSA PSPVV SG NV L+C S++    F+L +EG+      LNS  H  G  +A
Sbjct: 121 AYIKPTLSAQPSPVVNSGGNVILQCDSQVAFDGFSLCKEGEDEHPQCLNSQPHARGSSRA 180

Query: 179 LFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           +F +GP++ S R  +RCY Y++N+PY WS PSD L+LLV GVS+KPSL    GP+V P E
Sbjct: 181 IFSVGPVSPSRRWWYRCYAYDSNSPYEWSLPSDLLELLVLGVSKKPSLSVQPGPIVAPEE 240

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
            LTLQCGSD GY R+ LYK+G     Q  G QPQAGLSQANFTL PVSRSYGGQYRCYGA
Sbjct: 241 TLTLQCGSDAGYNRFVLYKDGERDFLQLAGAQPQAGLSQANFTLGPVSRSYGGQYRCYGA 300

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKE 358
           HN+SSEWSAPSDPLDILIAGQ  DR SLSVQPGPTV SGE VTLLCQS   M TFLLTKE
Sbjct: 301 HNLSSEWSAPSDPLDILIAGQFYDRVSLSVQPGPTVASGENVTLLCQSQGWMQTFLLTKE 360

Query: 359 GAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           GAA  P RLRS Y + KYQAEFPM PVTSAHAGTYRCYGS+SS PYLL+HPS+PLELVVS
Sbjct: 361 GAADDPWRLRSTYQSQKYQAEFPMGPVTSAHAGTYRCYGSQSSKPYLLTHPSDPLELVVS 420

Query: 419 GAT-ETLNPAQKKSDSKTAPHLQDYTVEN-------------LIRMGVAGLVLLFLGILL 464
           G +    +P    + +   P  Q  T                +I + VA ++LL L +LL
Sbjct: 421 GPSGGPSSPTTGPTSTSAGPEDQPLTPTGSDPQSGLGRHLGVVIGILVAVILLLLLLLLL 480

Query: 465 F 465
           F
Sbjct: 481 F 481


>gi|5803070 leukocyte immunoglobulin-like receptor, subfamily B,
           member 5 isoform 2 [Homo sapiens]
          Length = 590

 Score =  523 bits (1346), Expect = e-148
 Identities = 288/492 (58%), Positives = 332/492 (67%), Gaps = 16/492 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MTL L+ L+  GLS+GPRT VQA  LPKP LWAEP  VI    PVT+WCQG LE + YRL
Sbjct: 1   MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA- 119
           DKEG   +R     LE   K K  IPS +++ AGRY CYY++PAGWSEPSDPLELV T  
Sbjct: 61  DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           Y+ PTL ALPSPVV SG NVTL+C +  GL  F L+EE + +L  TL S +   G  QAL
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQAL 179

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           FP+GP+T S R  FRCY Y    P VWS PSD L++LV GVSRKPSLL  QG VV  G +
Sbjct: 180 FPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGS 239

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY  + LYKEG   L Q  G+QPQAGLSQANFTL PVSRS+GGQYRCYGAH
Sbjct: 240 LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 299

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+S  WSAPSDPLDILIAG I D P+LSVQPGP V SGE VTLLCQSW  + TF LTKEG
Sbjct: 300 NLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEG 359

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AAHPPL L+S Y ++++QAEF MSPVTSA  GTYRCY +  S PYLLS PS P ELVVSG
Sbjct: 360 AAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSG 419

Query: 420 ATETLNPAQKKSDSKTAPHLQDYTVENL-------------IRMGVAGLVLLFLGILLFE 466
            +   + +   S     P  Q  T   L               + VA ++LLFL +L   
Sbjct: 420 PSGDPSLSPTGSTPTPGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFL-LLFLL 478

Query: 467 AQHSQRSPPRCS 478
            +H  +S  R S
Sbjct: 479 LRHRHQSKHRTS 490


>gi|125987591 leukocyte immunoglobulin-like receptor, subfamily B,
           member 5 isoform 1 [Homo sapiens]
          Length = 591

 Score =  521 bits (1342), Expect = e-148
 Identities = 288/493 (58%), Positives = 334/493 (67%), Gaps = 17/493 (3%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MTL L+ L+  GLS+GPRT VQA  LPKP LWAEP  VI    PVT+WCQG LE + YRL
Sbjct: 1   MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA- 119
           DKEG   +R     LE   K K  IPS +++ AGRY CYY++PAGWSEPSDPLELV T  
Sbjct: 61  DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGF 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           Y+ PTL ALPSPVV SG NVTL+C +  GL  F L+EE + +L  TL S +   G  QAL
Sbjct: 121 YAEPTLLALPSPVVASGGNVTLQCDTLDGLLTFVLVEE-EQKLPRTLYSQKLPKGPSQAL 179

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           FP+GP+T S R  FRCY Y    P VWS PSD L++LV GVSRKPSLL  QG VV  G +
Sbjct: 180 FPVGPVTPSCRWRFRCYYYYRKNPQVWSNPSDLLEILVPGVSRKPSLLIPQGSVVARGGS 239

Query: 240 LTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAH 299
           LTLQC SDVGY  + LYKEG   L Q  G+QPQAGLSQANFTL PVSRS+GGQYRCYGAH
Sbjct: 240 LTLQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAH 299

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           N+S  WSAPSDPLDILIAG I D P+LSVQPGP V SGE VTLLCQSW  + TF LTKEG
Sbjct: 300 NLSPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEG 359

Query: 360 AAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           AAHPPL L+S Y ++++QAEF MSPVTSA  GTYRCY +  S PYLLS PS P ELVVSG
Sbjct: 360 AAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSG 419

Query: 420 AT---------ETLNPAQKKSDSKTAPHLQDYT-----VENLIRMGVAGLVLLFLGILLF 465
            +          T  PA  +    T   L   +     +  +  + VA ++LLFL +L  
Sbjct: 420 PSGDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFL-LLFL 478

Query: 466 EAQHSQRSPPRCS 478
             +H  +S  R S
Sbjct: 479 LLRHRHQSKHRTS 491


>gi|125987593 leukocyte immunoglobulin-like receptor, subfamily B,
           member 5 isoform 3 [Homo sapiens]
          Length = 491

 Score =  340 bits (873), Expect = 1e-93
 Identities = 198/371 (53%), Positives = 235/371 (63%), Gaps = 21/371 (5%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
           +PTL A P+ V+  G  VTL C   L    + L +EG   L W            +A F 
Sbjct: 28  KPTLWAEPASVIARGKPVTLWCQGPLETEEYRLDKEG---LPWARKRQNPLEPGAKAKFH 84

Query: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
           +    + + G +RCY YE  TP  WSEPSDPL+L+ +GVSRKPSLL  QG VV  G +LT
Sbjct: 85  IPSTVYDSAGRYRCY-YE--TPAGWSEPSDPLELVATGVSRKPSLLIPQGSVVARGGSLT 141

Query: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNV 301
           LQC SDVGY  + LYKEG   L Q  G+QPQAGLSQANFTL PVSRS+GGQYRCYGAHN+
Sbjct: 142 LQCRSDVGYDIFVLYKEGEHDLVQGSGQQPQAGLSQANFTLGPVSRSHGGQYRCYGAHNL 201

Query: 302 SSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAA 361
           S  WSAPSDPLDILIAG I D P+LSVQPGP V SGE VTLLCQSW  + TF LTKEGAA
Sbjct: 202 SPRWSAPSDPLDILIAGLIPDIPALSVQPGPKVASGENVTLLCQSWHQIDTFFLTKEGAA 261

Query: 362 HPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGAT 421
           HPPL L+S Y ++++QAEF MSPVTSA  GTYRCY +  S PYLLS PS P ELVVSG +
Sbjct: 262 HPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSAIRSYPYLLSSPSYPQELVVSGPS 321

Query: 422 ---------ETLNPAQKKSDSKTAPHLQDYT-----VENLIRMGVAGLVLLFLGILLFEA 467
                     T  PA  +    T   L   +     +  +  + VA ++LLFL +L    
Sbjct: 322 GDPSLSPTGSTPTPAGPEDQPLTPTGLDPQSGLGRHLGVVTGVSVAFVLLLFL-LLFLLL 380

Query: 468 QHSQRSPPRCS 478
           +H  +S  R S
Sbjct: 381 RHRHQSKHRTS 391



 Score =  266 bits (680), Expect = 3e-71
 Identities = 162/353 (45%), Positives = 207/353 (58%), Gaps = 7/353 (1%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MTL L+ L+  GLS+GPRT VQA  LPKP LWAEP  VI    PVT+WCQG LE + YRL
Sbjct: 1   MTLTLSVLICLGLSVGPRTCVQAGTLPKPTLWAEPASVIARGKPVTLWCQGPLETEEYRL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTAY 120
           DKEG   +R     LE   K K  IPS +++ AGRY CYY++PAGWSEPSDPLELV T  
Sbjct: 61  DKEGLPWARKRQNPLEPGAKAKFHIPSTVYDSAGRYRCYYETPAGWSEPSDPLELVATGV 120

Query: 121 SR-PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           SR P+L      VV  G ++TL+C S +G   F L +EG+H L    +  Q   G  QA 
Sbjct: 121 SRKPSLLIPQGSVVARGGSLTLQCRSDVGYDIFVLYKEGEHDLVQG-SGQQPQAGLSQAN 179

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSG-VSRKPSLLTLQGPVVTPGE 238
           F +GP++ S+ G +RCYG  N +P  WS PSDPL +L++G +   P+L    GP V  GE
Sbjct: 180 FTLGPVSRSHGGQYRCYGAHNLSPR-WSAPSDPLDILIAGLIPDIPALSVQPGPKVASGE 238

Query: 239 NLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA 298
           N+TL C S      + L KEGA   P     + Q+   QA F++SPV+ + GG YRCY A
Sbjct: 239 NVTLLCQSWHQIDTFFLTKEGAAHPPLCLKSKYQSYRHQAEFSMSPVTSAQGGTYRCYSA 298

Query: 299 -HNVSSEWSAPSDPLDILIAGQISDRPSLS-VQPGPTVTSGEKVTLLCQSWDP 349
             +     S+PS P +++++G   D PSLS     PT    E   L     DP
Sbjct: 299 IRSYPYLLSSPSYPQELVVSGPSGD-PSLSPTGSTPTPAGPEDQPLTPTGLDP 350


>gi|239758088 PREDICTED: similar to leucocyte immunoglobulin-like
           receptor, partial [Homo sapiens]
          Length = 256

 Score =  276 bits (706), Expect = 3e-74
 Identities = 148/256 (57%), Positives = 174/256 (67%), Gaps = 1/256 (0%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           MT ILT L+  GLSL PRT VQA  LPKP LWAEPG VIT  +PVT+ CQG+LE Q Y L
Sbjct: 1   MTPILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHL 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQS-PAGWSEPSDPLELVVTA 119
            +E  +         E   K +  I S+ WEHAGRY C Y S  AG SE SDPLELVVTA
Sbjct: 61  YREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGSHTAGLSESSDPLELVVTA 120

Query: 120 YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQAL 179
           YS+PTLSALPSPVVTSG NVT++C S++    F L +EG+      LNSH H  G  +A+
Sbjct: 121 YSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAI 180

Query: 180 FPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGEN 239
           F +GP++ S R ++RCYGY++  PYVWS PSD L LLV GVS+KPSL    GPVV PGE 
Sbjct: 181 FSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSKKPSLSVQPGPVVAPGEK 240

Query: 240 LTLQCGSDVGYIRYTL 255
           LT QCGSD GY R+ L
Sbjct: 241 LTFQCGSDPGYDRFVL 256



 Score =  141 bits (356), Expect = 1e-33
 Identities = 100/230 (43%), Positives = 128/230 (55%), Gaps = 10/230 (4%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
           +PTL A P  V+T G  VTLRC   L    + L  E    L W     Q    K Q  FP
Sbjct: 28  KPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTAL-WITRIPQELVKKGQ--FP 84

Query: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
           +  +T+ + G + C  Y ++T  + SE SDPL+L+V+  S KP+L  L  PVVT G N+T
Sbjct: 85  ILSITWEHAGRYCCI-YGSHTAGL-SESSDPLELVVTAYS-KPTLSALPSPVVTSGGNVT 141

Query: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQA-GLSQANFTLSPVSRSYGGQYRCYGAHN 300
           +QC S V +  + L KEG D  PQ       A G S+A F++ PVS S    YRCYG  +
Sbjct: 142 IQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDS 201

Query: 301 -VSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDP 349
                WS PSD L +L+ G +S +PSLSVQPGP V  GEK+T  C S DP
Sbjct: 202 RAPYVWSLPSDLLGLLVPG-VSKKPSLSVQPGPVVAPGEKLTFQCGS-DP 249



 Score =  107 bits (267), Expect = 3e-23
 Identities = 74/214 (34%), Positives = 108/214 (50%), Gaps = 8/214 (3%)

Query: 211 DPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQ 270
           DP   + +G   KP+L    G V+T G  +TL+C   +    Y LY+E    L     R 
Sbjct: 16  DPRTHVQAGPLPKPTLWAEPGSVITQGSPVTLRCQGSLETQEYHLYREKKTALWIT--RI 73

Query: 271 PQAGLSQANFTLSPVSRSYGGQYRC-YGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQ 329
           PQ  + +  F +  ++  + G+Y C YG+H      S  SDPL++++      +P+LS  
Sbjct: 74  PQELVKKGQFPILSITWEHAGRYCCIYGSHTAGL--SESSDPLELVVTAY--SKPTLSAL 129

Query: 330 PGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSA 388
           P P VTSG  VT+ C S      F+L KEG    P  L S   A    +A F + PV+ +
Sbjct: 130 PSPVVTSGGNVTIQCDSQVAFDGFILCKEGEDEHPQCLNSHSHARGSSRAIFSVGPVSPS 189

Query: 389 HAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATE 422
              +YRCYG  S  PY+ S PS+ L L+V G ++
Sbjct: 190 RRWSYRCYGYDSRAPYVWSLPSDLLGLLVPGVSK 223


>gi|32895361 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 3 [Homo sapiens]
          Length = 265

 Score =  271 bits (694), Expect = 8e-73
 Identities = 146/235 (62%), Positives = 163/235 (69%), Gaps = 1/235 (0%)

Query: 5   LTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEG 64
           L  LL  GLSLGPRT VQA NL K  LWAEPG VI+  N VTI CQGTLEAQ YRL KEG
Sbjct: 23  LMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 82

Query: 65  NSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRP 123
           +         LE +NK + SIPSM   HAGRY CYY SPAGWSEPSDPLELVVT  Y++P
Sbjct: 83  SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 142

Query: 124 TLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMG 183
           TLSALPSPVVTSG NVTL+C SRL   RF L EEGDH+LSWTL+S     G+FQALFP+G
Sbjct: 143 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 202

Query: 184 PLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
           P+T S+R   RCYG   +   VWSEPSD L++ VSG        T+QG     GE
Sbjct: 203 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 257



 Score =  130 bits (326), Expect = 4e-30
 Identities = 83/215 (38%), Positives = 121/215 (56%), Gaps = 8/215 (3%)

Query: 121 SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALF 180
           S+ TL A P  V++ G +VT+RC   L    + L++EG      T N  +    K +A F
Sbjct: 45  SKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEP---KNKARF 101

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
            +  +T  + G +RCY Y   +P  WSEPSDPL+L+V+G   KP+L  L  PVVT GEN+
Sbjct: 102 SIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 158

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGA- 298
           TLQCGS + + R+ L +EG   L      Q   +G  QA F + PV+ S+    RCYG+ 
Sbjct: 159 TLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSR 218

Query: 299 HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPT 333
            ++   WS PSD L+I ++G+ +   S ++Q   T
Sbjct: 219 RHILQVWSEPSDLLEIPVSGEEATVFSSTIQGSQT 253



 Score =  117 bits (294), Expect = 2e-26
 Identities = 76/209 (36%), Positives = 116/209 (55%), Gaps = 8/209 (3%)

Query: 218 SGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQ-PQAGLS 276
           +G   K +L    G V++ G ++T++C   +    Y L KEG+   P+    Q P    +
Sbjct: 41  AGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLEPKN 97

Query: 277 QANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTS 336
           +A F++  ++  + G+YRCY  +   + WS PSDPL++++ G   ++P+LS  P P VTS
Sbjct: 98  KARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPSPVVTS 154

Query: 337 GEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-MYGAHKYQAEFPMSPVTSAHAGTYRC 395
           GE VTL C S      F+LT+EG       L S +  + ++QA FP+ PVT +H    RC
Sbjct: 155 GENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRC 214

Query: 396 YGSRSSNPYLLSHPSEPLELVVSGATETL 424
           YGSR     + S PS+ LE+ VSG   T+
Sbjct: 215 YGSRRHILQVWSEPSDLLEIPVSGEEATV 243


>gi|32490553 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 1 [Homo sapiens]
          Length = 299

 Score =  268 bits (686), Expect = 7e-72
 Identities = 141/218 (64%), Positives = 158/218 (72%), Gaps = 1/218 (0%)

Query: 5   LTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEG 64
           L  LL  GLSLGPRT VQA NL K  LWAEPG VI+  N VTI CQGTLEAQ YRL KEG
Sbjct: 23  LMVLLCLGLSLGPRTHVQAGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEG 82

Query: 65  NSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRP 123
           +         LE +NK + SIPSM   HAGRY CYY SPAGWSEPSDPLELVVT  Y++P
Sbjct: 83  SPEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKP 142

Query: 124 TLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMG 183
           TLSALPSPVVTSG NVTL+C SRL   RF L EEGDH+LSWTL+S     G+FQALFP+G
Sbjct: 143 TLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVG 202

Query: 184 PLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVS 221
           P+T S+R   RCYG   +   VWSEPSD L++ VSG +
Sbjct: 203 PVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAA 240



 Score =  192 bits (488), Expect = 6e-49
 Identities = 113/259 (43%), Positives = 160/259 (61%), Gaps = 8/259 (3%)

Query: 218 SGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQ-PQAGLS 276
           +G   K +L    G V++ G ++T++C   +    Y L KEG+   P+    Q P    +
Sbjct: 41  AGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGS---PEPWDTQNPLEPKN 97

Query: 277 QANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTS 336
           +A F++  ++  + G+YRCY  +   + WS PSDPL++++ G   ++P+LS  P P VTS
Sbjct: 98  KARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDPLELVVTG-FYNKPTLSALPSPVVTS 154

Query: 337 GEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-MYGAHKYQAEFPMSPVTSAHAGTYRC 395
           GE VTL C S      F+LT+EG       L S +  + ++QA FP+ PVT +H    RC
Sbjct: 155 GENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRC 214

Query: 396 YGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGL 455
           YGSR     + S PS+ LE+ VSGA + L+P+Q KSDS TA HLQDY VENLIRMG+AGL
Sbjct: 215 YGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNKSDSGTASHLQDYAVENLIRMGMAGL 274

Query: 456 VLLFLGILLFEAQHSQRSP 474
           +L+ LGIL+F+  HSQRSP
Sbjct: 275 ILVVLGILIFQDWHSQRSP 293



 Score =  128 bits (321), Expect = 1e-29
 Identities = 80/200 (40%), Positives = 114/200 (57%), Gaps = 8/200 (4%)

Query: 121 SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALF 180
           S+ TL A P  V++ G +VT+RC   L    + L++EG      T N  +    K +A F
Sbjct: 45  SKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEP---KNKARF 101

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
            +  +T  + G +RCY Y   +P  WSEPSDPL+L+V+G   KP+L  L  PVVT GEN+
Sbjct: 102 SIPSMTEHHAGRYRCYYY---SPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENV 158

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGA- 298
           TLQCGS + + R+ L +EG   L      Q   +G  QA F + PV+ S+    RCYG+ 
Sbjct: 159 TLQCGSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSR 218

Query: 299 HNVSSEWSAPSDPLDILIAG 318
            ++   WS PSD L+I ++G
Sbjct: 219 RHILQVWSEPSDLLEIPVSG 238


>gi|32895365 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 4 [Homo sapiens]
          Length = 253

 Score =  249 bits (635), Expect = 5e-66
 Identities = 132/215 (61%), Positives = 149/215 (69%), Gaps = 1/215 (0%)

Query: 25  NLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84
           NL K  LWAEPG VI+  N VTI CQGTLEAQ YRL KEG+         LE +NK + S
Sbjct: 31  NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFS 90

Query: 85  IPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTLRC 143
           IPSM   HAGRY CYY SPAGWSEPSDPLELVVT  Y++PTLSALPSPVVTSG NVTL+C
Sbjct: 91  IPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQC 150

Query: 144 ASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTP 203
            SRL   RF L EEGDH+LSWTL+S     G+FQALFP+GP+T S+R   RCYG   +  
Sbjct: 151 GSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHIL 210

Query: 204 YVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGE 238
            VWSEPSD L++ VSG        T+QG     GE
Sbjct: 211 QVWSEPSDLLEIPVSGEEATVFSSTIQGSQTGCGE 245



 Score =  132 bits (331), Expect = 1e-30
 Identities = 90/246 (36%), Positives = 130/246 (52%), Gaps = 22/246 (8%)

Query: 104 AGWSEPSDPLE--------------LVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGL 149
           A WS PS  L+              L +   S+ TL A P  V++ G +VT+RC   L  
Sbjct: 2   APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61

Query: 150 GRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEP 209
             + L++EG      T N  +    K +A F +  +T  + G +RCY Y   +P  WSEP
Sbjct: 62  QEYRLVKEGSPEPWDTQNPLEP---KNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115

Query: 210 SDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGR 269
           SDPL+L+V+G   KP+L  L  PVVT GEN+TLQCGS + + R+ L +EG   L      
Sbjct: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175

Query: 270 Q-PQAGLSQANFTLSPVSRSYGGQYRCYGA-HNVSSEWSAPSDPLDILIAGQISDRPSLS 327
           Q   +G  QA F + PV+ S+    RCYG+  ++   WS PSD L+I ++G+ +   S +
Sbjct: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATVFSST 235

Query: 328 VQPGPT 333
           +Q   T
Sbjct: 236 IQGSQT 241



 Score =  122 bits (306), Expect = 8e-28
 Identities = 84/234 (35%), Positives = 123/234 (52%), Gaps = 21/234 (8%)

Query: 206 WSEPSDPLQ-------------LLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252
           WS PS  LQ             LL  G   K +L    G V++ G ++T++C   +    
Sbjct: 4   WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63

Query: 253 YTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDP 311
           Y L KEG+   P+    Q P    ++A F++  ++  + G+YRCY  +   + WS PSDP
Sbjct: 64  YRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDP 118

Query: 312 LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-M 370
           L++++ G   ++P+LS  P P VTSGE VTL C S      F+LT+EG       L S +
Sbjct: 119 LELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177

Query: 371 YGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETL 424
             + ++QA FP+ PVT +H    RCYGSR     + S PS+ LE+ VSG   T+
Sbjct: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGEEATV 231


>gi|32895363 leukocyte immunoglobulin-like receptor subfamily A
           member 5 isoform 2 [Homo sapiens]
          Length = 287

 Score =  246 bits (627), Expect = 5e-65
 Identities = 127/198 (64%), Positives = 144/198 (72%), Gaps = 1/198 (0%)

Query: 25  NLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84
           NL K  LWAEPG VI+  N VTI CQGTLEAQ YRL KEG+         LE +NK + S
Sbjct: 31  NLSKATLWAEPGSVISRGNSVTIRCQGTLEAQEYRLVKEGSPEPWDTQNPLEPKNKARFS 90

Query: 85  IPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTLRC 143
           IPSM   HAGRY CYY SPAGWSEPSDPLELVVT  Y++PTLSALPSPVVTSG NVTL+C
Sbjct: 91  IPSMTEHHAGRYRCYYYSPAGWSEPSDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQC 150

Query: 144 ASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTP 203
            SRL   RF L EEGDH+LSWTL+S     G+FQALFP+GP+T S+R   RCYG   +  
Sbjct: 151 GSRLRFDRFILTEEGDHKLSWTLDSQLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHIL 210

Query: 204 YVWSEPSDPLQLLVSGVS 221
            VWSEPSD L++ VSG +
Sbjct: 211 QVWSEPSDLLEIPVSGAA 228



 Score =  197 bits (500), Expect = 2e-50
 Identities = 121/284 (42%), Positives = 167/284 (58%), Gaps = 21/284 (7%)

Query: 206 WSEPSDPLQ-------------LLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252
           WS PS  LQ             LL  G   K +L    G V++ G ++T++C   +    
Sbjct: 4   WSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEAQE 63

Query: 253 YTLYKEGADGLPQRPGRQ-PQAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDP 311
           Y L KEG+   P+    Q P    ++A F++  ++  + G+YRCY  +   + WS PSDP
Sbjct: 64  YRLVKEGS---PEPWDTQNPLEPKNKARFSIPSMTEHHAGRYRCY--YYSPAGWSEPSDP 118

Query: 312 LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRS-M 370
           L++++ G   ++P+LS  P P VTSGE VTL C S      F+LT+EG       L S +
Sbjct: 119 LELVVTG-FYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDSQL 177

Query: 371 YGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKK 430
             + ++QA FP+ PVT +H    RCYGSR     + S PS+ LE+ VSGA + L+P+Q K
Sbjct: 178 TPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSGAADNLSPSQNK 237

Query: 431 SDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLFEAQHSQRSP 474
           SDS TA HLQDY VENLIRMG+AGL+L+ LGIL+F+  HSQRSP
Sbjct: 238 SDSGTASHLQDYAVENLIRMGMAGLILVVLGILIFQDWHSQRSP 281



 Score =  130 bits (326), Expect = 4e-30
 Identities = 87/231 (37%), Positives = 123/231 (53%), Gaps = 22/231 (9%)

Query: 104 AGWSEPSDPLE--------------LVVTAYSRPTLSALPSPVVTSGVNVTLRCASRLGL 149
           A WS PS  L+              L +   S+ TL A P  V++ G +VT+RC   L  
Sbjct: 2   APWSHPSAQLQPVGGDAVSPALMVLLCLGNLSKATLWAEPGSVISRGNSVTIRCQGTLEA 61

Query: 150 GRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEP 209
             + L++EG      T N  +    K +A F +  +T  + G +RCY Y   +P  WSEP
Sbjct: 62  QEYRLVKEGSPEPWDTQNPLEP---KNKARFSIPSMTEHHAGRYRCYYY---SPAGWSEP 115

Query: 210 SDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGR 269
           SDPL+L+V+G   KP+L  L  PVVT GEN+TLQCGS + + R+ L +EG   L      
Sbjct: 116 SDPLELVVTGFYNKPTLSALPSPVVTSGENVTLQCGSRLRFDRFILTEEGDHKLSWTLDS 175

Query: 270 Q-PQAGLSQANFTLSPVSRSYGGQYRCYGA-HNVSSEWSAPSDPLDILIAG 318
           Q   +G  QA F + PV+ S+    RCYG+  ++   WS PSD L+I ++G
Sbjct: 176 QLTPSGQFQALFPVGPVTPSHRWMLRCYGSRRHILQVWSEPSDLLEIPVSG 226


>gi|125987588 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 2 [Homo sapiens]
          Length = 447

 Score =  241 bits (614), Expect = 1e-63
 Identities = 131/238 (55%), Positives = 159/238 (66%), Gaps = 8/238 (3%)

Query: 6   TSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGN 65
           T+LL  GLSLGPRT +QA  LPKP LWAEPG VI+W N VTIWCQGTLEA+ YRLDKE +
Sbjct: 6   TALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEES 65

Query: 66  SMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-AYSRPT 124
                    LE +NK + SIPSM  ++AGRY CYY+SP GWS+PSDPLELV+T AYS+PT
Sbjct: 66  PAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPT 125

Query: 125 LSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGP 184
           LSALPSP+VTSG +VTL C SR  +  F LI+E        L S +H   + QA FPM P
Sbjct: 126 LSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRS-EHGAQQHQAEFPMSP 184

Query: 185 LTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKP------SLLTLQGPVVTP 236
           +T  + GT+RC+     + Y+ S PSDPL+L+VSG    P      S+ T  GP   P
Sbjct: 185 VTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQP 242



 Score =  191 bits (484), Expect = 2e-48
 Identities = 114/266 (42%), Positives = 157/266 (59%), Gaps = 17/266 (6%)

Query: 212 PLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQP 271
           P   + +G   KP+L    G V++ G ++T+ C   +    Y L KE +     R  + P
Sbjct: 17  PRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDR--QNP 74

Query: 272 QAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPG 331
               ++A F++  ++  Y G+YRCY    V   WS PSDPL++++ G  S +P+LS  P 
Sbjct: 75  LEPKNKARFSIPSMTEDYAGRYRCYYRSPVG--WSQPSDPLELVMTGAYS-KPTLSALPS 131

Query: 332 PTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAG 391
           P VTSG+ VTLLCQS  PM TFLL KE AAHP L LRS +GA ++QAEFPMSPVTS H G
Sbjct: 132 PLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGG 191

Query: 392 TYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDSKTA-----PHLQDYTVEN 446
           TYRC+ S   + YLLSHPS+PLEL+VSG+ E   P+  +S S  A     P +   +V +
Sbjct: 192 TYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPH 251

Query: 447 L-------IRMGVAGLVLLFLGILLF 465
                   + +GV  + +L L +LLF
Sbjct: 252 SGLRRHWEVLIGVLVVSILLLSLLLF 277



 Score =  112 bits (279), Expect = 1e-24
 Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 12/217 (5%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
           +PTL A P  V++ G +VT+ C   L    + L +E +    W   +      K  A F 
Sbjct: 28  KPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE-ESPAPWDRQNPLEPKNK--ARFS 84

Query: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
           +  +T    G +RCY     +P  WS+PSDPL+L+++G   KP+L  L  P+VT G+++T
Sbjct: 85  IPSMTEDYAGRYRCY---YRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVT 141

Query: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNV 301
           L C S      + L KE A         +  A   QA F +SPV+  +GG YRC+ +H  
Sbjct: 142 LLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGF 201

Query: 302 SSE-WSAPSDPLDILIAGQISD-RP----SLSVQPGP 332
           S    S PSDPL+++++G + D RP    S+S   GP
Sbjct: 202 SHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGP 238


>gi|125987585 leukocyte immunoglobulin-like receptor, subfamily B,
           member 4 isoform 1 [Homo sapiens]
          Length = 448

 Score =  241 bits (614), Expect = 1e-63
 Identities = 131/238 (55%), Positives = 159/238 (66%), Gaps = 8/238 (3%)

Query: 6   TSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGN 65
           T+LL  GLSLGPRT +QA  LPKP LWAEPG VI+W N VTIWCQGTLEA+ YRLDKE +
Sbjct: 6   TALLCLGLSLGPRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEES 65

Query: 66  SMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLELVVT-AYSRPT 124
                    LE +NK + SIPSM  ++AGRY CYY+SP GWS+PSDPLELV+T AYS+PT
Sbjct: 66  PAPWDRQNPLEPKNKARFSIPSMTEDYAGRYRCYYRSPVGWSQPSDPLELVMTGAYSKPT 125

Query: 125 LSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGP 184
           LSALPSP+VTSG +VTL C SR  +  F LI+E        L S +H   + QA FPM P
Sbjct: 126 LSALPSPLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRS-EHGAQQHQAEFPMSP 184

Query: 185 LTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKP------SLLTLQGPVVTP 236
           +T  + GT+RC+     + Y+ S PSDPL+L+VSG    P      S+ T  GP   P
Sbjct: 185 VTSVHGGTYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQP 242



 Score =  191 bits (484), Expect = 2e-48
 Identities = 114/266 (42%), Positives = 157/266 (59%), Gaps = 17/266 (6%)

Query: 212 PLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQP 271
           P   + +G   KP+L    G V++ G ++T+ C   +    Y L KE +     R  + P
Sbjct: 17  PRTHMQAGPLPKPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKEESPAPWDR--QNP 74

Query: 272 QAGLSQANFTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPG 331
               ++A F++  ++  Y G+YRCY    V   WS PSDPL++++ G  S +P+LS  P 
Sbjct: 75  LEPKNKARFSIPSMTEDYAGRYRCYYRSPVG--WSQPSDPLELVMTGAYS-KPTLSALPS 131

Query: 332 PTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAG 391
           P VTSG+ VTLLCQS  PM TFLL KE AAHP L LRS +GA ++QAEFPMSPVTS H G
Sbjct: 132 PLVTSGKSVTLLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGG 191

Query: 392 TYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKSDSKTA-----PHLQDYTVEN 446
           TYRC+ S   + YLLSHPS+PLEL+VSG+ E   P+  +S S  A     P +   +V +
Sbjct: 192 TYRCFSSHGFSHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGPEDQPLMPTGSVPH 251

Query: 447 L-------IRMGVAGLVLLFLGILLF 465
                   + +GV  + +L L +LLF
Sbjct: 252 SGLRRHWEVLIGVLVVSILLLSLLLF 277



 Score =  112 bits (279), Expect = 1e-24
 Identities = 76/217 (35%), Positives = 113/217 (52%), Gaps = 12/217 (5%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
           +PTL A P  V++ G +VT+ C   L    + L +E +    W   +      K  A F 
Sbjct: 28  KPTLWAEPGSVISWGNSVTIWCQGTLEAREYRLDKE-ESPAPWDRQNPLEPKNK--ARFS 84

Query: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
           +  +T    G +RCY     +P  WS+PSDPL+L+++G   KP+L  L  P+VT G+++T
Sbjct: 85  IPSMTEDYAGRYRCY---YRSPVGWSQPSDPLELVMTGAYSKPTLSALPSPLVTSGKSVT 141

Query: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNV 301
           L C S      + L KE A         +  A   QA F +SPV+  +GG YRC+ +H  
Sbjct: 142 LLCQSRSPMDTFLLIKERAAHPLLHLRSEHGAQQHQAEFPMSPVTSVHGGTYRCFSSHGF 201

Query: 302 SSE-WSAPSDPLDILIAGQISD-RP----SLSVQPGP 332
           S    S PSDPL+++++G + D RP    S+S   GP
Sbjct: 202 SHYLLSHPSDPLELIVSGSLEDPRPSPTRSVSTAAGP 238


>gi|134268642 killer cell immunoglobulin-like receptor, three
           domains, long cytoplasmic tail, 2 precursor [Homo
           sapiens]
          Length = 455

 Score =  229 bits (584), Expect = 4e-60
 Identities = 142/349 (40%), Positives = 205/349 (58%), Gaps = 23/349 (6%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGK-FQALF 180
           +P LSA PS VV  G +V L+C  R G   F L +E    +          HG+ FQ  F
Sbjct: 28  KPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIF-------HGRIFQESF 80

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
            MGP+T ++ GT+RC G   ++   WS PS+PL ++V+G  RKPSLL   GP++  GE +
Sbjct: 81  IMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETV 140

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHN 300
            LQC SDV +  + L++EG    P R   Q   G+S+ANF++ P+     G YRCYG+  
Sbjct: 141 ILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVP 200

Query: 301 VSS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
            S  + SAPSDPLDI+I G + ++PSLS QPGPTV +GE VTL C SW     + L++EG
Sbjct: 201 HSPYQLSAPSDPLDIVITG-LYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREG 259

Query: 360 AAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
            AH   RLR++   ++ +QA+FP+ P T  H GTYRC+GS  + P + S+ S+PL + V+
Sbjct: 260 EAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGSFRALPCVWSNSSDPLLVSVT 316

Query: 419 G--ATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLF 465
           G  ++   +P +  S S    HL        + +G + ++ LF+ +L F
Sbjct: 317 GNPSSSWPSPTEPSSKSGICRHLH-------VLIGTSVVIFLFILLLFF 358



 Score =  149 bits (376), Expect = 6e-36
 Identities = 111/317 (35%), Positives = 154/317 (48%), Gaps = 18/317 (5%)

Query: 28  KPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIPS 87
           KP L A P  V+     V + C        + L KE  S        +  E+ +   +  
Sbjct: 28  KPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIFQESFIMGPVTP 87

Query: 88  MMWEHAGRYHCYYQSP---AGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTLRC 143
               HAG Y C    P    GWS PS+PL ++VT  + +P+L A P P++ SG  V L+C
Sbjct: 88  A---HAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQC 144

Query: 144 ASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYENNTP 203
            S +    F L  EG       L    H+ G  +A F +GPL     GT+RCYG   ++P
Sbjct: 145 WSDVMFEHFFLHREGISEDPSRLVGQIHD-GVSKANFSIGPLMPVLAGTYRCYGSVPHSP 203

Query: 204 YVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGL 263
           Y  S PSDPL ++++G+  KPSL    GP V  GEN+TL C S   Y  Y L +EG +  
Sbjct: 204 YQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREG-EAH 262

Query: 264 PQRPGRQPQAGLS-QANFTLSPVSRSYGGQYRCYGAHN-VSSEWSAPSDPLDILIAGQIS 321
            +R    P+   + QA+F L P   ++GG YRC+G+   +   WS  SDPL + + G  S
Sbjct: 263 ERRLRAVPKVNRTFQADFPLGPA--THGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPS 320

Query: 322 DRPSLSVQPGPTVTSGE 338
                S  P PT  S +
Sbjct: 321 -----SSWPSPTEPSSK 332



 Score =  131 bits (329), Expect = 2e-30
 Identities = 83/206 (40%), Positives = 112/206 (54%), Gaps = 9/206 (4%)

Query: 219 GVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQA 278
           G   KP L      VV  G ++ LQC    G+  + LYKE    +P   GR     + Q 
Sbjct: 24  GGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGR-----IFQE 78

Query: 279 NFTLSPVSRSYGGQYRCYGAHNVS-SEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSG 337
           +F + PV+ ++ G YRC G+   S + WSAPS+PL I++ G    +PSL   PGP + SG
Sbjct: 79  SFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGN-HRKPSLLAHPGPLLKSG 137

Query: 338 EKVTLLCQSWDPMFT-FLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 396
           E V L C S D MF  F L +EG +  P RL         +A F + P+    AGTYRCY
Sbjct: 138 ETVILQCWS-DVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCY 196

Query: 397 GSRSSNPYLLSHPSEPLELVVSGATE 422
           GS   +PY LS PS+PL++V++G  E
Sbjct: 197 GSVPHSPYQLSAPSDPLDIVITGLYE 222



 Score =  112 bits (281), Expect = 6e-25
 Identities = 77/201 (38%), Positives = 106/201 (52%), Gaps = 9/201 (4%)

Query: 25  NLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSM--SRHILKTLESENKVK 82
           N  KP L A PGP++     V + C   +  + + L +EG S   SR + +  +  +K  
Sbjct: 120 NHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKAN 179

Query: 83  LSIPSMMWEHAGRYHCYYQ---SPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVN 138
            SI  +M   AG Y CY     SP   S PSDPL++V+T  Y +P+LSA P P V +G N
Sbjct: 180 FSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGEN 239

Query: 139 VTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198
           VTL C+S      + L  EG+      L +    +  FQA FP+GP T  + GT+RC+G 
Sbjct: 240 VTLSCSSWSSYDIYHLSREGEAH-ERRLRAVPKVNRTFQADFPLGPAT--HGGTYRCFGS 296

Query: 199 ENNTPYVWSEPSDPLQLLVSG 219
               P VWS  SDPL + V+G
Sbjct: 297 FRALPCVWSNSSDPLLVSVTG 317



 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 43/105 (40%), Positives = 55/105 (52%), Gaps = 7/105 (6%)

Query: 315 LIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAH 374
           L+ GQ  D+P LS +P   V  G  V L C        F+L KE  +H P+     +   
Sbjct: 22  LMGGQ--DKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPI-----FHGR 74

Query: 375 KYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
            +Q  F M PVT AHAGTYRC GSR  +    S PS PL ++V+G
Sbjct: 75  IFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTG 119


>gi|134268644 killer cell immunoglobulin-like receptor, three
           domains, long cytoplasmic tail, 1 precursor [Homo
           sapiens]
          Length = 444

 Score =  225 bits (573), Expect = 8e-59
 Identities = 139/349 (39%), Positives = 201/349 (57%), Gaps = 23/349 (6%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGK-FQALF 180
           +P LSA PS VV  G +VTLRC  R     F L +E    +          HG+ FQ  F
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPIF-------HGRIFQESF 80

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
            M P+T ++ G + C G   ++P  WS PS+P+ ++V+G  RKPSLL   GP+V  GE +
Sbjct: 81  NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTGNHRKPSLLAHPGPLVKSGERV 140

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA-H 299
            LQC SD+ +  + L+KEG    P R   Q   G+S+ANF++ P+  +  G YRCYG+  
Sbjct: 141 ILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHDGVSKANFSIGPMMLALAGTYRCYGSVT 200

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           +   + SAPSDPLDI++ G   ++PSLS QPGP V +GE VTL C S      + L++EG
Sbjct: 201 HTPYQLSAPSDPLDIVVTGPY-EKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259

Query: 360 AAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
            AH   RL ++   ++ +QA+FP+ P T  H GTYRC+GS   +PY  S PS+PL + V+
Sbjct: 260 GAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVT 316

Query: 419 G--ATETLNPAQKKSDSKTAPHLQDYTVENLIRMGVAGLVLLFLGILLF 465
           G  ++   +P +  S S    HL        I +G + +++LF+ +L F
Sbjct: 317 GNPSSSWPSPTEPSSKSGNPRHLH-------ILIGTSVVIILFILLLFF 358



 Score =  171 bits (433), Expect = 1e-42
 Identities = 122/343 (35%), Positives = 169/343 (49%), Gaps = 16/343 (4%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           M+L++ S+   GL L  R         KP L A P  V+     VT+ C        + L
Sbjct: 1   MSLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVV 117
            KE      HI        +   ++  +   HAG Y C   +  SP GWS PS+P+ ++V
Sbjct: 61  YKEDRI---HIPIFHGRIFQESFNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMV 117

Query: 118 TA-YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176
           T  + +P+L A P P+V SG  V L+C S +    F L +EG  +    L    H+ G  
Sbjct: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEGISKDPSRLVGQIHD-GVS 176

Query: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
           +A F +GP+  +  GT+RCYG   +TPY  S PSDPL ++V+G   KPSL    GP V  
Sbjct: 177 KANFSIGPMMLALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGPYEKPSLSAQPGPKVQA 236

Query: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296
           GE++TL C S   Y  Y L +EG     + P  +      QA+F L P   ++GG YRC+
Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294

Query: 297 GAHNVSS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGE 338
           G+   S  EWS PSDPL + + G  S     S  P PT  S +
Sbjct: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSK 332



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 39/98 (39%), Positives = 50/98 (51%), Gaps = 5/98 (5%)

Query: 322 DRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFP 381
           D+P LS  P   V  G  VTL C        F+L KE   H P+     +    +Q  F 
Sbjct: 27  DKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHIPI-----FHGRIFQESFN 81

Query: 382 MSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           MSPVT+AHAG Y C GS   +P   S PS P+ ++V+G
Sbjct: 82  MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPVVIMVTG 119


>gi|46488946 killer cell immunoglobulin-like receptor, three
           domains, long cytoplasmic tail, 3 [Homo sapiens]
          Length = 410

 Score =  219 bits (557), Expect = 6e-57
 Identities = 130/311 (41%), Positives = 186/311 (59%), Gaps = 12/311 (3%)

Query: 117 VTAYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176
           V    +P LSA P  VV+ G +VTL+C SRLG   F+L +E    +    N        F
Sbjct: 23  VGGQDKPFLSAWPGTVVSEGQHVTLQCRSRLGFNEFSLSKEDGMPVPELYNRI------F 76

Query: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
           +  F MGP+T ++ GT+RC     ++P  WS PS+P+ ++V+GV RKPSLL   GP+V  
Sbjct: 77  RNSFLMGPVTPAHAGTYRCCSSHPHSPTGWSAPSNPVVIMVTGVHRKPSLLAHPGPLVKS 136

Query: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296
           GE + LQC SDV + R+ L++EG    P R   Q     SQ N+++ P++ +  G YRC+
Sbjct: 137 GETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSMGPMTPALAGTYRCF 196

Query: 297 GA-HNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLL 355
           G+  ++  E SAPSDPLDI++ G +  +PSLS QPGPTV +GE VTL C S      + L
Sbjct: 197 GSVTHLPYELSAPSDPLDIVVVG-LYGKPSLSAQPGPTVQAGENVTLSCSSRSLFDIYHL 255

Query: 356 TKEGAAHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLE 414
           ++E  A   LRL ++   +  +QA FP+ PVT  H G YRC+GS  + P+  S PS+PL 
Sbjct: 256 SREAEA-GELRLTAVLRVNGTFQANFPLGPVT--HGGNYRCFGSFRALPHAWSDPSDPLP 312

Query: 415 LVVSGATETLN 425
           + V+G +  L+
Sbjct: 313 VSVTGNSRHLH 323



 Score =  171 bits (434), Expect = 1e-42
 Identities = 118/325 (36%), Positives = 164/325 (50%), Gaps = 15/325 (4%)

Query: 1   MTLILTSLLFFGLSL--GPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGY 58
           M+L++ S+   G  L  GP   V  ++  KP L A PG V++    VT+ C+  L    +
Sbjct: 1   MSLMVVSMACVGFFLLEGPWPHVGGQD--KPFLSAWPGTVVSEGQHVTLQCRSRLGFNEF 58

Query: 59  RLDKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLEL 115
            L KE       +   +   + +   +      HAG Y C   +  SP GWS PS+P+ +
Sbjct: 59  SLSKEDGMPVPELYNRIFRNSFLMGPVTPA---HAGTYRCCSSHPHSPTGWSAPSNPVVI 115

Query: 116 VVTAYSR-PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG 174
           +VT   R P+L A P P+V SG  V L+C S +   RF L  EG       L    H+ G
Sbjct: 116 MVTGVHRKPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAG 175

Query: 175 KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVV 234
             Q  + MGP+T +  GT+RC+G   + PY  S PSDPL ++V G+  KPSL    GP V
Sbjct: 176 S-QVNYSMGPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTV 234

Query: 235 TPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294
             GEN+TL C S   +  Y L +E   G  +        G  QANF L PV  ++GG YR
Sbjct: 235 QAGENVTLSCSSRSLFDIYHLSREAEAGELRLTAVLRVNGTFQANFPLGPV--THGGNYR 292

Query: 295 CYGAHN-VSSEWSAPSDPLDILIAG 318
           C+G+   +   WS PSDPL + + G
Sbjct: 293 CFGSFRALPHAWSDPSDPLPVSVTG 317



 Score =  116 bits (290), Expect = 5e-26
 Identities = 79/218 (36%), Positives = 115/218 (52%), Gaps = 15/218 (6%)

Query: 28  KPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMS--RHILKTLESENKVKLSI 85
           KP L A PGP++     V + C   +  + + L +EG +    R + +  ++ ++V  S+
Sbjct: 123 KPSLLAHPGPLVKSGETVILQCWSDVRFERFLLHREGITEDPLRLVGQLHDAGSQVNYSM 182

Query: 86  PSMMWEHAGRYHCY---YQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVTL 141
             M    AG Y C+      P   S PSDPL++VV   Y +P+LSA P P V +G NVTL
Sbjct: 183 GPMTPALAGTYRCFGSVTHLPYELSAPSDPLDIVVVGLYGKPSLSAQPGPTVQAGENVTL 242

Query: 142 RCASRLGLGRFTLIEE---GDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198
            C+SR     + L  E   G+ RL+  L  +    G FQA FP+GP+T    G +RC+G 
Sbjct: 243 SCSSRSLFDIYHLSREAEAGELRLTAVLRVN----GTFQANFPLGPVTHG--GNYRCFGS 296

Query: 199 ENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
               P+ WS+PSDPL + V+G SR   +L     V+ P
Sbjct: 297 FRALPHAWSDPSDPLPVSVTGNSRHLHVLIGTSVVIIP 334


>gi|134133244 killer cell immunoglobulin-like receptor, three
           domains, short cytoplasmic tail, 1 [Homo sapiens]
          Length = 382

 Score =  216 bits (550), Expect = 4e-56
 Identities = 130/317 (41%), Positives = 186/317 (58%), Gaps = 14/317 (4%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGK-FQALF 180
           +P LSA PS VV  G +VTLRC  R     F L +E    +          HG+ FQ  F
Sbjct: 28  KPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPIF-------HGRIFQEGF 80

Query: 181 PMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENL 240
            M P+T ++ G + C G   ++P  WS PS+P+ ++V+G  RKPSLL   GP+V  GE +
Sbjct: 81  NMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTGNHRKPSLLAHPGPLVKSGERV 140

Query: 241 TLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGA-H 299
            LQC SD+ +  + L+KE     P R   Q   G+S+ANF++  + R+  G YRCYG+  
Sbjct: 141 ILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHDGVSKANFSIGSMMRALAGTYRCYGSVT 200

Query: 300 NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEG 359
           +   + SAPSDPLDI++ G + ++PSLS QPGP V +GE VTL C S      + L++EG
Sbjct: 201 HTPYQLSAPSDPLDIVVTG-LYEKPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREG 259

Query: 360 AAHPPLRLRSMYGAHK-YQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
            AH   RL ++   ++ +QA+FP+ P T  H GTYRC+GS   +PY  S PS+PL + V+
Sbjct: 260 GAH-ERRLPAVRKVNRTFQADFPLGPAT--HGGTYRCFGSFRHSPYEWSDPSDPLLVSVT 316

Query: 419 GATETLNPAQKKSDSKT 435
           G   +  P+  +  SK+
Sbjct: 317 GNPSSSWPSPTEPSSKS 333



 Score =  164 bits (415), Expect = 2e-40
 Identities = 120/347 (34%), Positives = 167/347 (48%), Gaps = 16/347 (4%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           M L++ S+   GL L  R         KP L A P  V+     VT+ C        + L
Sbjct: 1   MLLMVVSMACVGLFLVQRAGPHMGGQDKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFML 60

Query: 61  DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVV 117
            KE           +  E     ++  +   HAG Y C   +  SP GWS PS+P+ ++V
Sbjct: 61  YKEDRIHVPIFHGRIFQEG---FNMSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMV 117

Query: 118 TA-YSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKF 176
           T  + +P+L A P P+V SG  V L+C S +    F L +E   +    L    H+ G  
Sbjct: 118 TGNHRKPSLLAHPGPLVKSGERVILQCWSDIMFEHFFLHKEWISKDPSRLVGQIHD-GVS 176

Query: 177 QALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTP 236
           +A F +G +  +  GT+RCYG   +TPY  S PSDPL ++V+G+  KPSL    GP V  
Sbjct: 177 KANFSIGSMMRALAGTYRCYGSVTHTPYQLSAPSDPLDIVVTGLYEKPSLSAQPGPKVQA 236

Query: 237 GENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCY 296
           GE++TL C S   Y  Y L +EG     + P  +      QA+F L P   ++GG YRC+
Sbjct: 237 GESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPLGPA--THGGTYRCF 294

Query: 297 GAHNVSS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTL 342
           G+   S  EWS PSDPL + + G  S     S  P PT  S +   L
Sbjct: 295 GSFRHSPYEWSDPSDPLLVSVTGNPS-----SSWPSPTEPSSKSGNL 336



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 39/98 (39%), Positives = 50/98 (51%), Gaps = 5/98 (5%)

Query: 322 DRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQAEFP 381
           D+P LS  P   V  G  VTL C        F+L KE   H P+     +    +Q  F 
Sbjct: 27  DKPFLSAWPSAVVPRGGHVTLRCHYRHRFNNFMLYKEDRIHVPI-----FHGRIFQEGFN 81

Query: 382 MSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSG 419
           MSPVT+AHAG Y C GS   +P   S PS P+ ++V+G
Sbjct: 82  MSPVTTAHAGNYTCRGSHPHSPTGWSAPSNPMVIMVTG 119



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 39/118 (33%), Positives = 53/118 (44%), Gaps = 6/118 (5%)

Query: 28  KPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLSIPS 87
           KP L A+PGP +     VT+ C        Y L +EG +  R +    +     +   P 
Sbjct: 223 KPSLSAQPGPKVQAGESVTLSCSSRSSYDMYHLSREGGAHERRLPAVRKVNRTFQADFPL 282

Query: 88  MMWEHAGRYHC---YYQSPAGWSEPSDPLELVVTAYSRPTLSALPSPVVTSGVNVTLR 142
               H G Y C   +  SP  WS+PSDPL + VT    P+ S+ PSP   S  +  LR
Sbjct: 283 GPATHGGTYRCFGSFRHSPYEWSDPSDPLLVSVT--GNPS-SSWPSPTEPSSKSGNLR 337


>gi|62632748 killer-cell Ig-like receptor [Homo sapiens]
          Length = 328

 Score =  203 bits (516), Expect = 3e-52
 Identities = 125/299 (41%), Positives = 176/299 (58%), Gaps = 12/299 (4%)

Query: 122 RPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFP 181
           +P LSA PSPVV+ G +V L+C SRLG   F+L +E    +    N        F+    
Sbjct: 28  KPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSLSKEDGMPVPELYNR------VFRNTVF 81

Query: 182 MGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLT 241
           +GP+T ++ GT+RC G   +    WS PS+PL ++V+GV RKPSLL   GP+V   E + 
Sbjct: 82  IGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTGVHRKPSLLAHPGPLVKSEETVI 141

Query: 242 LQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRCYGAHNV 301
           LQC SDV +  + L++EG      R   +   G+S+ANF++  +++   G YRCYG+   
Sbjct: 142 LQCWSDVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCYGSVPH 201

Query: 302 SS-EWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGA 360
           S  + SAPSDPLDI+I G +  +PSLS QP P V +GE VTL C S      + L++EG 
Sbjct: 202 SPYQLSAPSDPLDIVITG-LCGKPSLSAQPRPMVKAGESVTLSCSSRSSYDIYHLSREGE 260

Query: 361 AHPPLRLRSMYGAH-KYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVS 418
           AH  LR  ++   +  +QA FP+ P T  H GTYRC+GS   +PY  S  S+PL + V+
Sbjct: 261 AH-ELRFPAVPKVNGTFQANFPLGPAT--HGGTYRCFGSFRDSPYEWSDLSDPLLVSVT 316



 Score =  159 bits (403), Expect = 4e-39
 Identities = 114/331 (34%), Positives = 161/331 (48%), Gaps = 17/331 (5%)

Query: 1   MTLILTSLLFFGLSLGPRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRL 60
           M+L++ S+   G  L            KP L A P PV++    V + C+  L    + L
Sbjct: 1   MSLMVISMACVGFFLLQGAWTHEGGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSL 60

Query: 61  DKEGNSMSRHILKTLESENKV---KLSIPSMMWEHAGRYHCYYQSP---AGWSEPSDPLE 114
            KE        +   E  N+V    + I  +   HAG Y C    P    GWS PS+PL 
Sbjct: 61  SKEDG------MPVPELYNRVFRNTVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLV 114

Query: 115 LVVTAYSR-PTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNH 173
           ++VT   R P+L A P P+V S   V L+C S +    F L  EG    +  L    H+ 
Sbjct: 115 IMVTGVHRKPSLLAHPGPLVKSEETVILQCWSDVMFEHFLLHREGKFNDTLRLTGELHD- 173

Query: 174 GKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPV 233
           G  +A F +G +T    GT+RCYG   ++PY  S PSDPL ++++G+  KPSL     P+
Sbjct: 174 GVSKANFSIGRMTQDLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLCGKPSLSAQPRPM 233

Query: 234 VTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQY 293
           V  GE++TL C S   Y  Y L +EG     + P      G  QANF L P   ++GG Y
Sbjct: 234 VKAGESVTLSCSSRSSYDIYHLSREGEAHELRFPAVPKVNGTFQANFPLGPA--THGGTY 291

Query: 294 RCYGAHNVSS-EWSAPSDPLDILIAGQISDR 323
           RC+G+   S  EWS  SDPL + +   + ++
Sbjct: 292 RCFGSFRDSPYEWSDLSDPLLVSVTDSMKEK 322



 Score =  132 bits (331), Expect = 1e-30
 Identities = 82/203 (40%), Positives = 116/203 (57%), Gaps = 9/203 (4%)

Query: 219 GVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQA 278
           G   KP L     PVV+ GE++ LQC S +G+  ++L KE    +P+   R     + + 
Sbjct: 24  GGQDKPFLSAWPSPVVSEGEHVALQCRSRLGFNEFSLSKEDGMPVPELYNR-----VFRN 78

Query: 279 NFTLSPVSRSYGGQYRCYGAH-NVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSG 337
              + PV+ ++ G YRC G+H +  + WSAPS+PL I++ G +  +PSL   PGP V S 
Sbjct: 79  TVFIGPVTPAHAGTYRCRGSHPHFLTGWSAPSNPLVIMVTG-VHRKPSLLAHPGPLVKSE 137

Query: 338 EKVTLLCQSWDPMFT-FLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 396
           E V L C S D MF  FLL +EG  +  LRL         +A F +  +T   AGTYRCY
Sbjct: 138 ETVILQCWS-DVMFEHFLLHREGKFNDTLRLTGELHDGVSKANFSIGRMTQDLAGTYRCY 196

Query: 397 GSRSSNPYLLSHPSEPLELVVSG 419
           GS   +PY LS PS+PL++V++G
Sbjct: 197 GSVPHSPYQLSAPSDPLDIVITG 219


>gi|45505167 immunoglobulin superfamily, member 1 isoform 1 [Homo
           sapiens]
          Length = 1336

 Score =  178 bits (451), Expect = 1e-44
 Identities = 134/426 (31%), Positives = 205/426 (48%), Gaps = 30/426 (7%)

Query: 1   MTLILTSLLFFGLSLG---PRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTL-EA 55
           M  I+T+LL  GL  G     T +     PKP LWAE   P+  W N +T+WC+      
Sbjct: 562 MLFIVTALLCCGLCNGVLIEETEIVMPT-PKPELWAETNFPLAPWKN-LTLWCRSPSGST 619

Query: 56  QGYRLDKEGNSMSRHILKTLESENKVKLSIP--SMMWEHAGRYHCYYQSPAGWSEPSDPL 113
           + + L K+G       + T  +  +V+ + P  ++   H G YHC+       SEPS+ L
Sbjct: 620 KEFVLLKDGTGW----IATRPASEQVRAAFPLGALTQSHTGSYHCHSWEEMAVSEPSEAL 675

Query: 114 ELVVT-AYSRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHN 172
           ELV T    +P +SA P+     G  + LRC   L    F L +EG+      L +    
Sbjct: 676 ELVGTDILPKPVISASPT---IRGQELQLRCKGWLAGMGFALYKEGEQEPVQQLGAVGR- 731

Query: 173 HGKFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGP 232
               +A F +  +   + G + C  +    P+ WSEPS+PL+L++  +  KP   T   P
Sbjct: 732 ----EAFFTIQRMEDKDEGNYSCRTHTEKRPFKWSEPSEPLELVIKEMYPKPFFKTWASP 787

Query: 233 VVTPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQ 292
           VVTPG  +T  C +   ++ + LYK+G++ +          G S A+F +  V    GG 
Sbjct: 788 VVTPGARVTFNCSTPHQHMSFILYKDGSE-IASSDRSWASPGASAAHFLIISVGIGDGGN 846

Query: 293 YRCYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFT 352
           Y C   +   S WS PSDP+++++  +   +P+L  QPGP V  G+ V L CQ       
Sbjct: 847 YSC--RYYDFSIWSEPSDPVELVVT-EFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMR 903

Query: 353 FLLTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEP 412
           F L +EG AH PL+ RS+ G     A+F +  V +  +G Y C    ++     S+ S P
Sbjct: 904 FALLQEG-AHVPLQFRSVSG---NSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMP 959

Query: 413 LELVVS 418
           L + V+
Sbjct: 960 LMIWVT 965



 Score =  166 bits (419), Expect = 6e-41
 Identities = 140/453 (30%), Positives = 208/453 (45%), Gaps = 41/453 (9%)

Query: 17   PRTRVQAENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLE 76
            P   V  E  PKP L A+PGPV+     V + CQGT +   + L +EG  +         
Sbjct: 863  PVELVVTEFYPKPTLLAQPGPVVFPGKSVILRCQGTFQGMRFALLQEGAHVPLQFRSV-- 920

Query: 77   SENKVKLSIPSMMWEHAGRYHC-YYQSPAG--WSEPSDPLELVVT-AYSRPTLSALPSPV 132
            S N     + ++  E +G Y C YY++      S  S PL + VT  + +P L A PS V
Sbjct: 921  SGNSADFLLHTVGAEDSGNYSCIYYETTMSNRGSYLSMPLMIWVTDTFPKPWLFAEPSSV 980

Query: 133  VTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGT 192
            V  G NVTL C   +    + L +EG+   S  L     N G F    P+  ++ ++ G 
Sbjct: 981  VPMGQNVTLWCRGPVHGVGYILHKEGE-ATSMQLWGSTSNDGAF----PITNISGTSMGR 1035

Query: 193  FRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIR 252
            + C  + + T  +  +PS+ L+LLV+G+  KPSLL   GP+V PGEN+TLQC  ++    
Sbjct: 1036 YSCCYHPDWTSSIKIQPSNTLELLVTGLLPKPSLLAQPGPMVAPGENMTLQCQGELPDST 1095

Query: 253  YTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYRC-YGAHNVSSEWSAPSDP 311
            + L KEGA    Q P  Q +    +A+F +  V     G Y C Y   +     S  SD 
Sbjct: 1096 FVLLKEGA----QEPLEQQRPSGYRADFWMPAVRGEDSGIYSCVYYLDSTPFAASNHSDS 1151

Query: 312  LDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMY 371
            L+I +  +   +PSLS  P      G+ +TL C+   P   F+L  +G   P        
Sbjct: 1152 LEIWVTDK-PPKPSLSAWPSTMFKLGKDITLQCRGPLPGVEFVLEHDGEEAPQ------- 1203

Query: 372  GAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELVVSGATETLNPAQKKS 431
                   +F ++ V     G Y C     + P + S PS+PLELV               
Sbjct: 1204 -QFSEDGDFVINNVEGKGIGNYSCSYRLQAYPDIWSEPSDPLELV--------------- 1247

Query: 432  DSKTAPHLQDYTVENLIRMGVAGLVLLFLGILL 464
                 P  Q+ TV N++R  +  +V++ LG++L
Sbjct: 1248 -GAAGPVAQECTVGNIVRSSLIVVVVVALGVVL 1279



 Score =  128 bits (322), Expect = 1e-29
 Identities = 119/398 (29%), Positives = 176/398 (44%), Gaps = 28/398 (7%)

Query: 26  LPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKLS 84
           LPKPI W +   P +   N V I C G L+   + L KEG   +  +   + +      S
Sbjct: 129 LPKPIFWIQAETPALPGCN-VNILCHGWLQDLVFMLFKEG--YAEPVDYQVPTGTMAIFS 185

Query: 85  IPSMMWEHAGRYHC---YYQSPAGWSEPSDPLELVVTA-YSRPTLSALPSPVVTSGVNVT 140
           I ++  E  G Y C       P  WSEPS+PL+LVV   Y +PTL+A P P++  G ++ 
Sbjct: 186 IDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIMAPGESLN 245

Query: 141 LRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGYEN 200
           LRC   +    F L+   D   S+    +     K +A F    L   + G + C+ Y+ 
Sbjct: 246 LRCQGPIYGMTFALMRVEDLEKSF----YHKKTIKNEANFFFQSLKIQDTGHYLCFYYDA 301

Query: 201 NTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVVTPGENLTLQCGSDVGYIRYTLYKEGA 260
           +  Y  S  SD L++ V+    K  LL     VV  G+N++L+C   V  +   LYK+G 
Sbjct: 302 S--YRGSLLSDVLKIWVTDTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGE 359

Query: 261 DGLPQRPGRQPQAGLSQAN--FTLSPVSRSYGGQYRCYGAHNVSSEWSAPSDPLDILIAG 318
           D    +P +   A     N  F L+ V+ S  G Y C+      +    PS     L+  
Sbjct: 360 D----KPLQFLDATSIDDNTSFFLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVV 415

Query: 319 QISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFLLTKEGAAHPPLRLRSMYGAHKYQA 378
               +PSLS  P      G+ +TL C+   P+  F L  E         R  +       
Sbjct: 416 DKPPKPSLSAWPSTVFKLGKAITLQCRVSHPVLEFSLEWEE--------RETFQKFSVNG 467

Query: 379 EFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLELV 416
           +F +S V     GTY C     ++P + SH SEPL+L+
Sbjct: 468 DFIISNVDGKGTGTYSCSYRVETHPNIWSHRSEPLKLM 505



 Score =  112 bits (281), Expect = 6e-25
 Identities = 113/402 (28%), Positives = 172/402 (42%), Gaps = 26/402 (6%)

Query: 1   MTLILTSLLF-FGLSLGPRTRVQAENLPKPILWAEPG-PVITWHNPVTIWCQGTLEAQGY 58
           M    T LLF   +SLG  + V     P+P LW E   P   W N +T+WC+        
Sbjct: 12  MLKTFTVLLFCIRMSLGMTSIVMD---PQPELWIESNYPQAPWEN-ITLWCRSPSRISSK 67

Query: 59  RL---DKEGNSMSRHILKTLESENKVKLSIPSMMWEHAGRYHCYYQSPAGWSEPSDPLEL 115
            L   DK   +  R   KT +    V   I ++   +AG Y C Y    GWS+PS  LEL
Sbjct: 68  FLLLKDKTQMTWIRPSHKTFQ----VSFLIGALTESNAGLYRCCYWKETGWSKPSKVLEL 123

Query: 116 VVTAY-SRPTLSALPSPVVTSGVNVTLRCASRLGLGRFTLIEEGDHRLSWTLNSHQHNHG 174
                  +P            G NV + C   L    F L +EG          +Q   G
Sbjct: 124 EAPGQLPKPIFWIQAETPALPGCNVNILCHGWLQDLVFMLFKEGYAEPV----DYQVPTG 179

Query: 175 KFQALFPMGPLTFSNRGTFRCYGYENNTPYVWSEPSDPLQLLVSGVSRKPSLLTLQGPVV 234
              A+F +  LT  + G + C  +    P +WSEPS+PL+L+V+G+  KP+L    GP++
Sbjct: 180 TM-AIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLKLVVAGLYPKPTLTAHPGPIM 238

Query: 235 TPGENLTLQCGSDVGYIRYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294
            PGE+L L+C   +  + + L +   + L ++     +   ++ANF    +     G Y 
Sbjct: 239 APGESLNLRCQGPIYGMTFALMR--VEDL-EKSFYHKKTIKNEANFFFQSLKIQDTGHYL 295

Query: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354
           C+  ++ S   S  SD L I +      +  L  +P   V  G+ V+L C+         
Sbjct: 296 CF-YYDASYRGSLLSDVLKIWVTDTF-PKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLA 353

Query: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCY 396
           L K+G   P   L +   +      F ++ VT +  G Y C+
Sbjct: 354 LYKKGEDKPLQFLDAT--SIDDNTSFFLNNVTYSDTGIYSCH 393



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 57/185 (30%), Positives = 81/185 (43%), Gaps = 12/185 (6%)

Query: 236 PGENLTLQCGSDVGYI-RYTLYKEGADGLPQRPGRQPQAGLSQANFTLSPVSRSYGGQYR 294
           P EN+TL C S      ++ L K+       RP  +      Q +F +  ++ S  G YR
Sbjct: 50  PWENITLWCRSPSRISSKFLLLKDKTQMTWIRPSHKT----FQVSFLIGALTESNAGLYR 105

Query: 295 CYGAHNVSSEWSAPSDPLDILIAGQISDRPSLSVQPGPTVTSGEKVTLLCQSWDPMFTFL 354
           C   +   + WS PS  L++   GQ+  +P   +Q       G  V +LC  W     F+
Sbjct: 106 C--CYWKETGWSKPSKVLELEAPGQLP-KPIFWIQAETPALPGCNVNILCHGWLQDLVFM 162

Query: 355 LTKEGAAHPPLRLRSMYGAHKYQAEFPMSPVTSAHAGTYRCYGSRSSNPYLLSHPSEPLE 414
           L KEG A P +  +   G     A F +  +T    G Y C       P L S PS PL+
Sbjct: 163 LFKEGYAEP-VDYQVPTGT---MAIFSIDNLTPEDEGVYICRTHIQMLPTLWSEPSNPLK 218

Query: 415 LVVSG 419
           LVV+G
Sbjct: 219 LVVAG 223



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 52/198 (26%), Positives = 86/198 (43%), Gaps = 15/198 (7%)

Query: 24  ENLPKPILWAEPGPVITWHNPVTIWCQGTLEAQGYRLDKEGNSMSRHILKTLESENKVKL 83
           +  PK  L A P  V+     V++ C+G ++  G  L K+G       L     ++    
Sbjct: 318 DTFPKTWLLARPSAVVQMGQNVSLRCRGPVDGVGLALYKKGEDKPLQFLDATSIDDNTSF 377

Query: 84  SIPSMMWEHAGRYHCYYQSPAGWS--EPS-DPLEL-VVTAYSRPTLSALPSPVVTSGVNV 139
            + ++ +   G Y C+Y      S   PS + +EL VV    +P+LSA PS V   G  +
Sbjct: 378 FLNNVTYSDTGIYSCHYLLTWKTSIRMPSHNTVELMVVDKPPKPSLSAWPSTVFKLGKAI 437

Query: 140 TLRCASRLGLGRFTL-IEEGDHRLSWTLNSHQHNHGKFQALFPMGPLTFSNRGTFRCYGY 198
           TL+C     +  F+L  EE +    +++N            F +  +     GT+ C   
Sbjct: 438 TLQCRVSHPVLEFSLEWEERETFQKFSVNGD----------FIISNVDGKGTGTYSCSYR 487

Query: 199 ENNTPYVWSEPSDPLQLL 216
               P +WS  S+PL+L+
Sbjct: 488 VETHPNIWSHRSEPLKLM 505


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,362,534
Number of Sequences: 37866
Number of extensions: 1117143
Number of successful extensions: 4620
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 77
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 3073
Number of HSP's gapped (non-prelim): 475
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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