Search of human proteins with 4505749

Search of human proteins with 4505749

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505749 phosphofructokinase, muscle [Homo sapiens]
         (780 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505749 phosphofructokinase, muscle [Homo sapiens]                1566   0.0  
gi|11321601 phosphofructokinase, platelet [Homo sapiens]             1129   0.0  
gi|48762920 liver phosphofructokinase [Homo sapiens]                 1129   0.0  
gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]              31   5.0  
gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]               31   5.0  
gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo sapi...    30   8.6  
gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]          30   8.6  

>gi|4505749 phosphofructokinase, muscle [Homo sapiens]
          Length = 780

 Score = 1566 bits (4055), Expect = 0.0
 Identities = 780/780 (100%), Positives = 780/780 (100%)

Query: 1   MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVD 60
           MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVD
Sbjct: 1   MTHEEHHAAKTLGIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVD 60

Query: 61  GGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDG 120
           GGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDG
Sbjct: 61  GGDHIKEATWESVSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDG 120

Query: 121 SLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS 180
           SLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS
Sbjct: 121 SLTGADTFRSEWSDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDS 180

Query: 181 ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWE 240
           ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWE
Sbjct: 181 ALHRIMEIVDAITTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWE 240

Query: 241 EHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQ 300
           EHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQ
Sbjct: 241 EHLCRRLSETRTRGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQ 300

Query: 301 RGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK 360
           RGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK
Sbjct: 301 RGGTPSAFDRILGSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTK 360

Query: 361 AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVR 420
           AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVR
Sbjct: 361 AMDEKKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVR 420

Query: 421 STVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQ 480
           STVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQ
Sbjct: 421 STVRIGLIQGNRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQ 480

Query: 481 ISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSV 540
           ISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSV
Sbjct: 481 ISANITKFNIQGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSV 540

Query: 541 GADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPF 600
           GADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPF
Sbjct: 541 GADTALNTICTTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPF 600

Query: 601 TIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLG 660
           TIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLG
Sbjct: 601 TIRDLQANVEHLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLG 660

Query: 661 HMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVF 720
           HMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVF
Sbjct: 661 HMQQGGSPTPFDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVF 720

Query: 721 QPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEAAV 780
           QPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEAAV
Sbjct: 721 QPVAELKDQTDFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRKRSGEAAV 780


>gi|11321601 phosphofructokinase, platelet [Homo sapiens]
          Length = 784

 Score = 1129 bits (2921), Expect = 0.0
 Identities = 552/760 (72%), Positives = 644/760 (84%), Gaps = 4/760 (0%)

Query: 13  GIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWES 72
           G GKAI VLTSGGDAQGMNAAVRAVVR+GI+ GA+V+F++EGYQG+VDGG +I EA WES
Sbjct: 22  GAGKAIGVLTSGGDAQGMNAAVRAVVRMGIYVGAKVYFIYEGYQGMVDGGSNIAEADWES 81

Query: 73  VSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEW 132
           VS +LQ+GGT+IGSARC+ FR REGRL+AA NL++RGITNLCVIGGDGSLTGA+ FR EW
Sbjct: 82  VSSILQVGGTIIGSARCQAFRTREGRLKAACNLLQRGITNLCVIGGDGSLTGANLFRKEW 141

Query: 133 SDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAI 192
           S LL +L + G+I  E   K +YLN+VG+VGSIDNDFCGTDMTIGTDSALHRI+E+VDAI
Sbjct: 142 SGLLEELARNGQIDKEAVQKYAYLNVVGMVGSIDNDFCGTDMTIGTDSALHRIIEVVDAI 201

Query: 193 TTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRT 252
            TTAQSHQRTFVLEVMGRHCGYLALV++L+CGADWVF+PE PP++ WEE +C +LSE R 
Sbjct: 202 MTTAQSHQRTFVLEVMGRHCGYLALVSALACGADWVFLPESPPEEGWEEQMCVKLSENRA 261

Query: 253 RGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRIL 312
           R  RLNIIIVAEGAID   KPITSE IK LVV +LGYDTRVT+LGHVQRGGTPSAFDRIL
Sbjct: 262 RKKRLNIIIVAEGAIDTQNKPITSEKIKELVVTQLGYDTRVTILGHVQRGGTPSAFDRIL 321

Query: 313 GSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALK 372
            SRMGVEAV+ALLE TPDTPACVVSL+GN AVRLPLMECVQ+T+DV KAMDE++F +A++
Sbjct: 322 ASRMGVEAVIALLEATPDTPACVVSLNGNHAVRLPLMECVQMTQDVQKAMDERRFQDAVR 381

Query: 373 LRGRSFMNNWEVYKLLAHVRP--PVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQG 430
           LRGRSF  N   YK LA   P   + K+  + VAV+NVGAPAAGMNAAVRS VR+G+  G
Sbjct: 382 LRGRSFAGNLNTYKRLAIKLPDDQIPKTNCN-VAVINVGAPAAGMNAAVRSAVRVGIADG 440

Query: 431 NRVLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNI 490
           +R+L ++DGF+G AKGQI+E GW+ VGGWTGQGGS LGTKR LP K  E+I+  +   +I
Sbjct: 441 HRMLAIYDGFDGFAKGQIKEIGWTDVGGWTGQGGSILGTKRVLPGKYLEEIATQMRTHSI 500

Query: 491 QGLVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTIC 550
             L+IIGGFEAY G LEL   R++ +E C+P V++PATVSNNVPGSDFS+GADTALNTI 
Sbjct: 501 NALLIIGGFEAYLGLLELSAAREKHEEFCVPMVMVPATVSNNVPGSDFSIGADTALNTIT 560

Query: 551 TTCDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVE 610
            TCDRIKQSA+GTKRRVFIIETMGGYCGYLA M GLAAGADAAYIFEEPF IRDLQ+NVE
Sbjct: 561 DTCDRIKQSASGTKRRVFIIETMGGYCGYLANMGGLAAGADAAYIFEEPFDIRDLQSNVE 620

Query: 611 HLVQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTP 670
           HL +KMKTT++RGLVLRNE C+ENYTTDFI+ LYSEEGKG+FD RKNVLGHMQQGG+P+P
Sbjct: 621 HLTEKMKTTIQRGLVLRNESCSENYTTDFIYQLYSEEGKGVFDCRKNVLGHMQQGGAPSP 680

Query: 671 FDRNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQT 730
           FDRNF TK+ A+AM W++ K+KE+   G+ F  T DS CVLG+ KR ++FQPVAELK QT
Sbjct: 681 FDRNFGTKISARAMEWITAKLKEARGRGKKF-TTDDSICVLGISKRNVIFQPVAELKKQT 739

Query: 731 DFEHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHI 770
           DFEHRIPKEQWWLKLRP++KILAKY+   D SD   LEH+
Sbjct: 740 DFEHRIPKEQWWLKLRPLMKILAKYKASYDVSDSGQLEHV 779


>gi|48762920 liver phosphofructokinase [Homo sapiens]
          Length = 780

 Score = 1129 bits (2920), Expect = 0.0
 Identities = 535/761 (70%), Positives = 644/761 (84%), Gaps = 1/761 (0%)

Query: 13  GIGKAIAVLTSGGDAQGMNAAVRAVVRVGIFTGARVFFVHEGYQGLVDGGDHIKEATWES 72
           G GKAI VLTSGGDAQGMNAAVRAV R+GI+ GA+VF ++EGY+GLV+GG++IK+A W S
Sbjct: 13  GAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLS 72

Query: 73  VSMMLQLGGTVIGSARCKDFREREGRLRAAYNLVKRGITNLCVIGGDGSLTGADTFRSEW 132
           VS ++QLGGT+IGSARCK F  REGR  AAYNLV+ GITNLCVIGGDGSLTGA+ FRSEW
Sbjct: 73  VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEW 132

Query: 133 SDLLSDLQKAGKITDEEATKSSYLNIVGLVGSIDNDFCGTDMTIGTDSALHRIMEIVDAI 192
             LL +L   GKI++  A   S+LNI GLVGSIDNDFCGTDMTIGTDSALHRIME++DAI
Sbjct: 133 GSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAI 192

Query: 193 TTTAQSHQRTFVLEVMGRHCGYLALVTSLSCGADWVFIPECPPDDDWEEHLCRRLSETRT 252
           TTTAQSHQRTFVLEVMGRHCGYLALV++L+ GADW+FIPE PP+D WE  +C RL ETR+
Sbjct: 193 TTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRS 252

Query: 253 RGSRLNIIIVAEGAIDKNGKPITSEDIKNLVVKRLGYDTRVTVLGHVQRGGTPSAFDRIL 312
           RGSRLNIII+AEGAID+NGKPI+S  +K+LVV+RLG+DTRVTVLGHVQRGGTPSAFDRIL
Sbjct: 253 RGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRIL 312

Query: 313 GSRMGVEAVMALLEGTPDTPACVVSLSGNQAVRLPLMECVQVTKDVTKAMDEKKFDEALK 372
            S+MG+EAVMALLE TPDTPACVV+LSGNQ+VRLPLMECVQ+TK+V KAMD+K+FDEA +
Sbjct: 313 SSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQ 372

Query: 373 LRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVRIGLIQGNR 432
           LRG SF NNW +YKLLAH +PP  KS + ++A++NVGAPAAGMNAAVRS VR G+  G+ 
Sbjct: 373 LRGGSFENNWNIYKLLAHQKPPKEKS-NFSLAILNVGAPAAGMNAAVRSAVRTGISHGHT 431

Query: 433 VLVVHDGFEGLAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQG 492
           V VVHDGFEGLAKGQ++E GW  V GW G+GGS LGTKRTLPK   E I  NI  + I  
Sbjct: 432 VYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHA 491

Query: 493 LVIIGGFEAYTGGLELMEGRKQFDELCIPFVVIPATVSNNVPGSDFSVGADTALNTICTT 552
           L+++GGFEAY G L+L+E R +++ELCI   VIPAT+SNNVPG+DFS+G+DTA+N    +
Sbjct: 492 LLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMES 551

Query: 553 CDRIKQSAAGTKRRVFIIETMGGYCGYLATMAGLAAGADAAYIFEEPFTIRDLQANVEHL 612
           CDRIKQSA+GTKRRVFI+ETMGGYCGYLAT+ G+A GADAAY+FE+PF I DL+ NVEH+
Sbjct: 552 CDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHM 611

Query: 613 VQKMKTTVKRGLVLRNEKCNENYTTDFIFNLYSEEGKGIFDSRKNVLGHMQQGGSPTPFD 672
            +KMKT ++RGLVLRNEKC++ YTT+F++NLYS EGKG+FD R NVLGH+QQGG+PTPFD
Sbjct: 612 TEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFD 671

Query: 673 RNFATKMGAKAMNWMSGKIKESYRNGRIFANTPDSGCVLGMRKRALVFQPVAELKDQTDF 732
           RN+ TK+G KAM W+S K++E YR GR+FAN PDS CV+G++K+A+ F PV ELK  TDF
Sbjct: 672 RNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDF 731

Query: 733 EHRIPKEQWWLKLRPILKILAKYEIDLDTSDHAHLEHITRK 773
           EHR+P+EQWWL LR +LK+LA+Y I +       LEH+TR+
Sbjct: 732 EHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRR 772


>gi|72534680 sex comb on midleg 1 isoform 1 [Homo sapiens]
          Length = 660

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 14/109 (12%)

Query: 390 HVRPPVSKSGSHTVAVMNVGAPAAGM-NAAVRSTVRIGLIQGNRVLVVHDGFEG------ 442
           H  PP   S SH    M +   A    N        IG ++G+ VLV  DG+ G      
Sbjct: 156 HKEPP---SPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWC 212

Query: 443 -LAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNI 490
                 I   GW  +   TG      GTK  +PK  +     N  K +I
Sbjct: 213 RFDSRDIFPVGWCSL---TGDNLQPPGTKVVIPKNPYPASDVNTEKPSI 258


>gi|6912642 sex comb on midleg 1 isoform 2 [Homo sapiens]
          Length = 591

 Score = 30.8 bits (68), Expect = 5.0
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 14/109 (12%)

Query: 390 HVRPPVSKSGSHTVAVMNVGAPAAGM-NAAVRSTVRIGLIQGNRVLVVHDGFEG------ 442
           H  PP   S SH    M +   A    N        IG ++G+ VLV  DG+ G      
Sbjct: 109 HKEPP---SPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGSEVLVTFDGWRGAFDYWC 165

Query: 443 -LAKGQIEEAGWSYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNI 490
                 I   GW  +   TG      GTK  +PK  +     N  K +I
Sbjct: 166 RFDSRDIFPVGWCSL---TGDNLQPPGTKVVIPKNPYPASDVNTEKPSI 211


>gi|11761619 GDP-mannose pyrophosphorylase B isoform 1 [Homo
           sapiens]
          Length = 387

 Score = 30.0 bits (66), Expect = 8.6
 Identities = 17/79 (21%), Positives = 33/79 (41%), Gaps = 5/79 (6%)

Query: 452 GW-----SYVGGWTGQGGSKLGTKRTLPKKSFEQISANITKFNIQGLVIIGGFEAYTGGL 506
           GW      +V  W G GG + G    LP K++  +   +    + G  +I   E Y  G 
Sbjct: 309 GWRCRVGQWVSLWAGLGGERGGECACLPDKAYPLLEVRMENVTVLGEDVIVNDELYLNGA 368

Query: 507 ELMEGRKQFDELCIPFVVI 525
            ++  +   + +  P +++
Sbjct: 369 SVLPHKSIGESVPEPRIIM 387


>gi|13899309 ribosomal protein S6 kinase-like 1 [Homo sapiens]
          Length = 541

 Score = 30.0 bits (66), Expect = 8.6
 Identities = 23/81 (28%), Positives = 39/81 (48%), Gaps = 2/81 (2%)

Query: 365 KKFDEALKLRGRSFMNNWEVYKLLAHVRPPVSKSGSHTVAVMNVGAPAAGMNAAVRSTVR 424
           K+  EA+KL+   ++   E      H++ P+S SG+   AV  V  PA G    V+S  R
Sbjct: 93  KERREAVKLKITKYLRRAEEI-FNCHLQRPLS-SGASPSAVQLVQDPATGGTFVVKSLPR 150

Query: 425 IGLIQGNRVLVVHDGFEGLAK 445
             ++   R+ ++  G   + K
Sbjct: 151 CHMVSRERLTIIPHGVPYMTK 171


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,619,387
Number of Sequences: 37866
Number of extensions: 1261193
Number of successful extensions: 2400
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 2366
Number of HSP's gapped (non-prelim): 7
length of query: 780
length of database: 18,247,518
effective HSP length: 110
effective length of query: 670
effective length of database: 14,082,258
effective search space: 9435112860
effective search space used: 9435112860
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.