Search of human proteins with 4503325

Search of human proteins with 4503325

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503325 deoxyhypusine synthase isoform a [Homo sapiens]
         (369 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503325 deoxyhypusine synthase isoform a [Homo sapiens]            743   0.0  
gi|7108338 deoxyhypusine synthase isoform b [Homo sapiens]            627   e-180
gi|7108340 deoxyhypusine synthase isoform c [Homo sapiens]            565   e-161
gi|54607014 TBC1 domain family, member 25 [Homo sapiens]               32   1.2  
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]         29   7.7  
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]         29   7.7  

>gi|4503325 deoxyhypusine synthase isoform a [Homo sapiens]
          Length = 369

 Score =  743 bits (1917), Expect = 0.0
 Identities = 369/369 (100%), Positives = 369/369 (100%)

Query: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60
           MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
Sbjct: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60

Query: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120
           RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
Sbjct: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120

Query: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180
           QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
Sbjct: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180

Query: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240
           DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
Sbjct: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240

Query: 241 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA 300
           LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA
Sbjct: 241 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA 300

Query: 301 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 360
           DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
Sbjct: 301 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 360

Query: 361 AFMHEKNED 369
           AFMHEKNED
Sbjct: 361 AFMHEKNED 369


>gi|7108338 deoxyhypusine synthase isoform b [Homo sapiens]
          Length = 322

 Score =  627 bits (1616), Expect = e-180
 Identities = 322/369 (87%), Positives = 322/369 (87%), Gaps = 47/369 (12%)

Query: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60
           MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
Sbjct: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60

Query: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120
           RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
Sbjct: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120

Query: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180
           QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
Sbjct: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180

Query: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240
           DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
Sbjct: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240

Query: 241 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA 300
           LGDMIFFHSYKNPGLVLDIVE                                       
Sbjct: 241 LGDMIFFHSYKNPGLVLDIVE--------------------------------------- 261

Query: 301 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 360
                   AQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
Sbjct: 262 --------AQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 313

Query: 361 AFMHEKNED 369
           AFMHEKNED
Sbjct: 314 AFMHEKNED 322


>gi|7108340 deoxyhypusine synthase isoform c [Homo sapiens]
          Length = 313

 Score =  565 bits (1456), Expect = e-161
 Identities = 297/369 (80%), Positives = 301/369 (81%), Gaps = 56/369 (15%)

Query: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60
           MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG
Sbjct: 1   MEGSLEREAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFG 60

Query: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120
           RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV
Sbjct: 61  RAVQQVNAMIEKKLEPLSQDEDQHADLTQSRRPLTSCTIFLGYTSNLISSGIRETIRYLV 120

Query: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180
           QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE
Sbjct: 121 QHNMVDVLVTTAGGVEEDLIKCLAPTYLGEFSLRGKELRENGINRIGNLLVPNENYCKFE 180

Query: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240
           DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS
Sbjct: 181 DWLMPILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVYYWAQKNHIPVFSPALTDGS 240

Query: 241 LGDMIFFHSYKNPGLVLDIVEDLRLINTQAIFAKCTGMIILGGGVVKHHIANANLMRNGA 300
                                                   LG  +  H   N  L+ +  
Sbjct: 241 ----------------------------------------LGDMIFFHSYKNPGLVLDIV 260

Query: 301 DYAVYINTAQEFDGSDSGARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 360
           +                GARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD
Sbjct: 261 E----------------GARPDEAVSWGKIRVDAQPVKVYADASLVFPLLVAETFAQKMD 304

Query: 361 AFMHEKNED 369
           AFMHEKNED
Sbjct: 305 AFMHEKNED 313


>gi|54607014 TBC1 domain family, member 25 [Homo sapiens]
          Length = 688

 Score = 31.6 bits (70), Expect = 1.2
 Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 17/104 (16%)

Query: 172 PNENYCKFEDW--LMP--------ILDQMVMEQNTEGVKWTPSKMIARLGKEINNPESVY 221
           P+E+    EDW  + P        +L +      T  + +T S ++ ++G+ ++  + V 
Sbjct: 126 PSEDSPLLEDWDIISPKDVIGSDVLLAEKRSSLTTAALPFTQS-ILTQVGRTLSKVQQVL 184

Query: 222 YWAQKNHIPVFSPALTDGSLGDMIFFHSYKNPGLVLDIVEDLRL 265
            W+    +  F P L+D        FH+Y N    L   E+LRL
Sbjct: 185 SWSYGEDVKPFKPPLSDAE------FHTYLNHEGQLSRPEELRL 222


>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
          Length = 1251

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 2/88 (2%)

Query: 8   EAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVN 67
           E PA A A  L  S  +PPE T+ R    NR  + + L  +      +     R V +  
Sbjct: 631 EEPAAADA--LGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSK 688

Query: 68  AMIEKKLEPLSQDEDQHADLTQSRRPLT 95
             IE +    S   D   +  Q   PL+
Sbjct: 689 EFIETESSSSSSSSDSDLESEQEEYPLS 716


>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
          Length = 1226

 Score = 28.9 bits (63), Expect = 7.7
 Identities = 24/88 (27%), Positives = 34/88 (38%), Gaps = 2/88 (2%)

Query: 8   EAPAGALAAVLKHSSTLPPESTQVRGYDFNRGVNYRALLEAFGTTGFQATNFGRAVQQVN 67
           E PA A A  L  S  +PPE T+ R    NR  + + L  +      +     R V +  
Sbjct: 606 EEPAAADA--LGTSVVVPPEPTKTRPCGNNRASHRKELRSSVTCEKRRTRGLSRIVPKSK 663

Query: 68  AMIEKKLEPLSQDEDQHADLTQSRRPLT 95
             IE +    S   D   +  Q   PL+
Sbjct: 664 EFIETESSSSSSSSDSDLESEQEEYPLS 691


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,382,312
Number of Sequences: 37866
Number of extensions: 566412
Number of successful extensions: 999
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 994
Number of HSP's gapped (non-prelim): 8
length of query: 369
length of database: 18,247,518
effective HSP length: 104
effective length of query: 265
effective length of database: 14,309,454
effective search space: 3792005310
effective search space used: 3792005310
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.