Guide to the Human Genome
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Search of human proteins with 4501901

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4501901 aminoacylase 1 [Homo sapiens]
         (408 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4501901 aminoacylase 1 [Homo sapiens]                              840   0.0  
gi|47458827 peptidase M20 domain containing 1 [Homo sapiens]           59   6e-09
gi|21071039 carnosinase 1 [Homo sapiens]                               43   6e-04
gi|239747578 PREDICTED: hypothetical protein XP_002347666 [Homo ...    31   2.3  
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       30   3.9  
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto...    30   3.9  

>gi|4501901 aminoacylase 1 [Homo sapiens]
          Length = 408

 Score =  840 bits (2170), Expect = 0.0
 Identities = 408/408 (100%), Positives = 408/408 (100%)

Query: 1   MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVV 60
           MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVV
Sbjct: 1   MTSKGPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYVV 60

Query: 61  TVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQ 120
           TVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQ
Sbjct: 61  TVLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQ 120

Query: 121 YLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP 180
           YLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP
Sbjct: 121 YLEAVRRLKVEGHRFPRTIHMTFVPDEEVGGHQGMELFVQRPEFHALRAGFALDEGIANP 180

Query: 181 TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSN 240
           TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSN
Sbjct: 181 TDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDTAAEKLHKVVNSILAFREKEWQRLQSN 240

Query: 241 PHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEG 300
           PHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEG
Sbjct: 241 PHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAPDVDFKAFEEQLQSWCQAAGEG 300

Query: 301 VTLEFAQKWMHPQVTPTDDSNPWWAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVPAL 360
           VTLEFAQKWMHPQVTPTDDSNPWWAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVPAL
Sbjct: 301 VTLEFAQKWMHPQVTPTDDSNPWWAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVPAL 360

Query: 361 GFSPMNRTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSDS 408
           GFSPMNRTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSDS
Sbjct: 361 GFSPMNRTPVLLHDHDERLHEAVFLRGVDIYTRLLPALASVPALPSDS 408


>gi|47458827 peptidase M20 domain containing 1 [Homo sapiens]
          Length = 502

 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 67/261 (25%), Positives = 106/261 (40%), Gaps = 44/261 (16%)

Query: 62  VLTWPGTNPTLSSILLNSHTDVVPVFKEHWSHDPFEAFKDSEGYIYARGAQDMKCVSIQY 121
           + T  G++P+L   LL +H DVVP  +E W   PF    + +G IY RG  D K   +  
Sbjct: 107 LFTIQGSDPSLQPYLLMAHFDVVPAPEEGWEVPPFSGL-ERDGVIYGRGTLDDKNSVMAL 165

Query: 122 LEAVRRLKVEGHRFPRTIHMTFVPDEEVG--GHQGMELFVQ----RPEFHALRAGFALDE 175
           L+A+  L +  +   R+  ++   DEE    G Q +   +Q    +  F     GF LD+
Sbjct: 166 LQALELLLIRKYIPRRSFFISLGHDEESSGTGAQRISALLQSRGVQLAFIVDEGGFILDD 225

Query: 176 GIAN-PTDAFTVFYSERSPWWVRVTSTGRPGHASRFMEDT-------AAEKLHKV----- 222
            I N       +  SE+    + +      GH+S   ++T       A  +L +      
Sbjct: 226 FIPNFKKPIALIAVSEKGSMNLMLQVNMTSGHSSAPPKETSIGILAAAVSRLEQTPMPII 285

Query: 223 --------------------VNSILA----FREKEWQRLQSNPHLKEGSVTSVNLTKLEG 258
                               VN IL+    F     + ++ NP       T+  LT  + 
Sbjct: 286 FGSGTVVTVLQQLANEFPFPVNIILSNPWLFEPLISRFMERNPLTNAIIRTTTALTIFKA 345

Query: 259 GVAYNVIPATMSASFDFRVAP 279
           GV +NVIP    A+ +FR+ P
Sbjct: 346 GVKFNVIPPVAQATVNFRIHP 366


>gi|21071039 carnosinase 1 [Homo sapiens]
          Length = 507

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 7/120 (5%)

Query: 32  GAAVAFFEETARQLGLGCQKVEVAPGYVVTVLTWPGTNPTLSSILLNSHTDVVPVFK-EH 90
           GA VA  +   +QL  G Q + + P     +L   G++PT  ++    H DV P  + + 
Sbjct: 89  GARVASVDMGPQQLPDG-QSLPIPP----VILAELGSDPTKGTVCFYGHLDVQPADRGDG 143

Query: 91  WSHDPFEAFKDSEGYIYARGAQDMKCVSIQYLEAVRRLKVEGHRFPRTIHMTFVPDEEVG 150
           W  DP+    + +G +Y RGA D K   + ++ AV   +      P  I       EE G
Sbjct: 144 WLTDPY-VLTEVDGKLYGRGATDNKGPVLAWINAVSAFRALEQDLPVNIKFIIEGMEEAG 202


>gi|239747578 PREDICTED: hypothetical protein XP_002347666 [Homo
           sapiens]
          Length = 294

 Score = 30.8 bits (68), Expect = 2.3
 Identities = 15/43 (34%), Positives = 23/43 (53%)

Query: 237 LQSNPHLKEGSVTSVNLTKLEGGVAYNVIPATMSASFDFRVAP 279
           ++ NP       T+  LT  + GV +NVIP    A+ +FR+ P
Sbjct: 140 MERNPLTNAIIRTTTALTIFKAGVKFNVIPPVAQATVNFRIHP 182


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)

Query: 2    TSK--GPEEEHPSVTLFRQYLRIRTVQPKPDYGAAVAFFEETARQLGLGCQKVEVAPGYV 59
            TSK  G  +  P++   +Q  +++ ++ +  + A       TA + G+G  ++  APG +
Sbjct: 2133 TSKTVGAAQLKPTLNQLKQTQKLQDMEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPGPL 2192

Query: 60   VTVLTWPGTNPTLS 73
             T +  PG  PTLS
Sbjct: 2193 STTVI-PGAAPTLS 2205


>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
           factor-associated, 170kDa [Homo sapiens]
          Length = 1849

 Score = 30.0 bits (66), Expect = 3.9
 Identities = 10/35 (28%), Positives = 20/35 (57%)

Query: 324 WAAFSRVCKDMNLTLEPEIMPAATDNRYIRAVGVP 358
           WAA  + CK + L ++P ++   +++ Y   + VP
Sbjct: 736 WAALQKECKAVTLAVQPRLLDILSEHLYYDEIAVP 770


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.134    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,496,503
Number of Sequences: 37866
Number of extensions: 740575
Number of successful extensions: 1346
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1340
Number of HSP's gapped (non-prelim): 8
length of query: 408
length of database: 18,247,518
effective HSP length: 105
effective length of query: 303
effective length of database: 14,271,588
effective search space: 4324291164
effective search space used: 4324291164
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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