Search of human proteins with 41352693

Search of human proteins with 41352693

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41352693 iron-responsive element binding protein 2 [Homo
sapiens]
         (963 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41352693 iron-responsive element binding protein 2 [Homo sapi...  1932   0.0  
gi|8659555 aconitase 1 [Homo sapiens]                                1030   0.0  
gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens]        172   2e-42
gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]           31   4.9  
gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo ...    31   4.9  
gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo ...    31   4.9  

>gi|41352693 iron-responsive element binding protein 2 [Homo
           sapiens]
          Length = 963

 Score = 1932 bits (5005), Expect = 0.0
 Identities = 963/963 (100%), Positives = 963/963 (100%)

Query: 1   MDAPKAGYAFEYLIETLNDSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKK 60
           MDAPKAGYAFEYLIETLNDSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKK
Sbjct: 1   MDAPKAGYAFEYLIETLNDSSHKKFFDVSKLGTKYDVLPYSIRVLLEAAVRNCDGFLMKK 60

Query: 61  EDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPAC 120
           EDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPAC
Sbjct: 61  EDVMNILDWKTKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPAC 120

Query: 121 PTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDS 180
           PTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDS
Sbjct: 121 PTDLTVDHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDS 180

Query: 181 GELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFK 240
           GELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFK
Sbjct: 181 GELGRNSGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFK 240

Query: 241 NVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIE 300
           NVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIE
Sbjct: 241 NVAVIPPGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIE 300

Query: 301 TEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGV 360
           TEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGV
Sbjct: 301 TEAVMLGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGV 360

Query: 361 SQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRN 420
           SQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRN
Sbjct: 361 SQLSIVDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRN 420

Query: 421 DQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIA 480
           DQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIA
Sbjct: 421 DQNSSGEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIA 480

Query: 481 AEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKP 540
           AEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKP
Sbjct: 481 AEKQKDIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKP 540

Query: 541 YIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGD 600
           YIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGD
Sbjct: 541 YIRTSLSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGD 600

Query: 601 LVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIY 660
           LVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIY
Sbjct: 601 LVTCGILSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIY 660

Query: 661 LHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRC 720
           LHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRC
Sbjct: 661 LHDIWPSREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRC 720

Query: 721 PSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPRE 780
           PSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPRE
Sbjct: 721 PSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPRE 780

Query: 781 FNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIP 840
           FNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIP
Sbjct: 781 FNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIP 840

Query: 841 LIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENAD 900
           LIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENAD
Sbjct: 841 LIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENAD 900

Query: 901 SLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVAR 960
           SLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVAR
Sbjct: 901 SLGLSGRETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVAR 960

Query: 961 KFS 963
           KFS
Sbjct: 961 KFS 963


>gi|8659555 aconitase 1 [Homo sapiens]
          Length = 889

 Score = 1030 bits (2663), Expect = 0.0
 Identities = 517/957 (54%), Positives = 686/957 (71%), Gaps = 76/957 (7%)

Query: 10  FEYLIETLND-SSHKKFFDVSKL-GTKYDVLPYSIRVLLEAAVRNCDGFLMKKEDVMNIL 67
           F +L E L+     KKFF+++KL  ++Y  LP+SIRVLLEAA+RNCD FL+KK+D+ NIL
Sbjct: 5   FAHLAEPLDPVQPGKKFFNLNKLEDSRYGRLPFSIRVLLEAAIRNCDEFLVKKQDIENIL 64

Query: 68  DWK-TKQSNVEVPFFPARVLLQDFTGIPAMVDFAAMREAVKTLGGDPEKVHPACPTDLTV 126
            W  T+  N+E                   V F   R  ++   G P  V          
Sbjct: 65  HWNVTQHKNIE-------------------VPFKPARVILQDFTGVPAVV---------- 95

Query: 127 DHSLQIDFSKCAIQNAPNPGGGDLQKAGKLSPLKVQPKKLPCRGQTTCRGSCDSGELGRN 186
                 DF+  A+++A    GGD +K   + P  +                         
Sbjct: 96  ------DFA--AMRDAVKKLGGDPEKINPVCPADL------------------------- 122

Query: 187 SGTFSSQIENTPILCPFHLQPVPEPETVLKNQEVEFGRNRERLQFFKWSSRVFKNVAVIP 246
                  + +  I   F+ +     +++ KNQ++EF RNRER +F KW S+ F N+ +IP
Sbjct: 123 -------VIDHSIQVDFNRRA----DSLQKNQDLEFERNRERFEFLKWGSQAFHNMRIIP 171

Query: 247 PGTGMAHQINLEYLSRVVFEEKDLLFPDSVVGTDSHITMVNGLGILGWGVGGIETEAVML 306
           PG+G+ HQ+NLEYL+RVVF++    +PDS+VGTDSH TM++GLGILGWGVGGIE EAVML
Sbjct: 172 PGSGIIHQVNLEYLARVVFDQDGYYYPDSLVGTDSHTTMIDGLGILGWGVGGIEAEAVML 231

Query: 307 GLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSIV 366
           G P+S+ LP+V+G  L G  +P VTS D+VL ITKHLRQVGV GKFVEFFG GV+QLSI 
Sbjct: 232 GQPISMVLPQVIGYRLMGKPHPLVTSTDIVLTITKHLRQVGVVGKFVEFFGPGVAQLSIA 291

Query: 367 DRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSSG 426
           DR TIANMCPEYGA  +FFPVD V++ +L  TG  + KL+ ++ YL+AV +FR+  + S 
Sbjct: 292 DRATIANMCPEYGATAAFFPVDEVSITYLVQTGRDEEKLKYIKKYLQAVGMFRDFNDPSQ 351

Query: 427 EPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQKD 486
           +P+++QV++++L ++VP  SGPKRPQD+VAV+DMK DF++CL  K GFKGFQ+A E   D
Sbjct: 352 DPDFTQVVELDLKTVVPCCSGPKRPQDKVAVSDMKKDFESCLGAKQGFKGFQVAPEHHND 411

Query: 487 IVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTSL 546
             +  Y+ +E+ L+HGSVVIAA+ SCTN  NPSVML AGLLAKKAV+AGL V PYI+TSL
Sbjct: 412 HKTFIYDNTEFTLAHGSVVIAAITSCTNTSNPSVMLGAGLLAKKAVDAGLNVMPYIKTSL 471

Query: 547 SPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGDLVTCGI 606
           SPGSG+VT+YL  SGV+PYLS+LGF++VGYGC TC+GN+ PL + V+ A+ QGDLV  G+
Sbjct: 472 SPGSGVVTYYLQESGVMPYLSQLGFDVVGYGCMTCIGNSGPLPEPVVEAITQGDLVAVGV 531

Query: 607 LSGNKNFEGRLCDCVRANYLASPPLVVAYAIAGTVNIDFQTEPLGTDPTGKNIYLHDIWP 666
           LSGN+NFEGR+    RANYLASPPLV+AYAIAGT+ IDF+ EPLG +  G+ ++L DIWP
Sbjct: 532 LSGNRNFEGRVHPNTRANYLASPPLVIAYAIAGTIRIDFEKEPLGVNAKGQQVFLKDIWP 591

Query: 667 SREEVHRVEEEHVILSMFKALKDKIEMGNKRWNSLEAPDSVLFPWDLKSTYIRCPSFFDK 726
           +R+E+  VE ++VI  MFK +  KIE  N+ WN+L  P   LF W+ KSTYI+ P FF+ 
Sbjct: 592 TRDEIQAVERQYVIPGMFKEVYQKIETVNESWNALATPSDKLFFWNSKSTYIKSPPFFEN 651

Query: 727 LTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLTPREFNSYGA 786
           LT +    ++I +A+VLL LGDSVTTDHISPAG+IARNS AA+YLTNRGLTPREFNSYG+
Sbjct: 652 LTLDLQPPKSIVDAYVLLNLGDSVTTDHISPAGNIARNSPAARYLTNRGLTPREFNSYGS 711

Query: 787 RRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKEGIPLIILAG 846
           RRGNDAVM RGTFANI+L N+F+ K AP+TIH PSG+ LDVF+AAE YQ+ G+PLI+LAG
Sbjct: 712 RRGNDAVMARGTFANIRLLNRFLNKQAPQTIHLPSGEILDVFDAAERYQQAGLPLIVLAG 771

Query: 847 KKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGENADSLGLSG 906
           K+YG+G+SRDWAAKGP+LLG+KAVLAESYE+IH+ +L+G+G+ PL++LPGENAD+LGL+G
Sbjct: 772 KEYGAGSSRDWAAKGPFLLGIKAVLAESYERIHRSNLVGMGVIPLEYLPGENADALGLTG 831

Query: 907 RETFSLTFPEELSPGITLNIQTSTGKVFSVIASFEDDVEITLYKHGGLLNFVARKFS 963
           +E +++  PE L P + + ++  TGK F  +  F+ DVE+T + +GG+LN++ RK +
Sbjct: 832 QERYTIIIPENLKPQMKVQVKLDTGKTFQAVMRFDTDVELTYFLNGGILNYMIRKMA 888


>gi|4501867 aconitase 2, mitochondrial precursor [Homo sapiens]
          Length = 780

 Score =  172 bits (435), Expect = 2e-42
 Identities = 189/722 (26%), Positives = 306/722 (42%), Gaps = 128/722 (17%)

Query: 247 PGTGMAHQINLEYLSRVVFEEKDLLFPDSV-VGTDSHITMVNGLGILGWGVGGIETEAVM 305
           PG+G+ HQI LE          +  +P  + +GTDSH     GLG +  GVGG +   VM
Sbjct: 168 PGSGIIHQIILE----------NYAYPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVM 217

Query: 306 LGLPVSLTLPEVVGCELTGSSNPFVTSIDVVLGITKHLRQVGVAGKFVEFFGSGVSQLSI 365
            G+P  L  P+V+G +LTGS + + +  DV+L +   L   G  G  VE+ G GV  +S 
Sbjct: 218 AGIPWELKCPKVIGVKLTGSLSGWSSPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISC 277

Query: 366 VDRTTIANMCPEYGAILSFFPVDNVTLKHLEHTGFSKAKLESMETYLKAVKLFRNDQNSS 425
               TI NM  E GA  S FP ++   K+L  TG         E        F++     
Sbjct: 278 TGMATICNMGAEIGATTSVFPYNHRMKKYLSKTG--------REDIANLADEFKDHLVPD 329

Query: 426 GEPEYSQVIQINLNSIVPSVSGPKRPQDRVAVTDMKSDFQACLNEKVGFKGFQIAAEKQK 485
               Y Q+I+INL+ + P ++GP  P     V ++                    AEK+ 
Sbjct: 330 PGCHYDQLIEINLSELKPHINGPFTPDLAHPVAEVGK-----------------VAEKEG 372

Query: 486 DIVSIHYEGSEYKLSHGSVVIAAVISCTNNCNPSVMLAAGLLAKKAVEAGLRVKPYIRTS 545
             + I               +  + SCTN+    +  +A  +AK+A+  GL+ K   + +
Sbjct: 373 WPLDIR--------------VGLIGSCTNSSYEDMGRSAA-VAKQALAHGLKCKS--QFT 415

Query: 546 LSPGSGMVTHYLSSSGVLPYLSKLGFEIVGYGCSTCVGNTAPLSDAVLNAVKQGDLVTCG 605
           ++PGS  +   +   G    L  LG  ++   C  C+G            +K+G+  T  
Sbjct: 416 ITPGSEQIRATIERDGYAQILRDLGGIVLANACGPCIGQWD------RKDIKKGEKNTI- 468

Query: 606 ILSGNKNFEGRL-CDCVRANYLASPPLVVAYAIAGTVNIDFQTEPL-GTDPTGKNIYLHD 663
           + S N+NF GR   +     ++ SP +V A AIAGT+  + +T+ L GTD  GK   L  
Sbjct: 469 VTSYNRNFTGRNDANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTD--GKKFRLEA 526

Query: 664 IWPSREEVHRVEEEHVILSMFKALKDK------IEMGNKRWNSLEAPDSVLFPWDLKSTY 717
             P  +E+ + E +    +     KD       +   ++R   LE  D     WD K   
Sbjct: 527 --PDADELPKGEFDPGQDTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDK----WDGKD-- 578

Query: 718 IRCPSFFDKLTKEPIALQAIENAHVLLYLGDSVTTDHISPAGSIARNSAAAKYLTNRGLT 777
                              +E+  +L+ +    TTDHIS AG   +       ++N  L 
Sbjct: 579 -------------------LEDLQILIKVKGKCTTDHISAAGPWLKFRGHLDNISNNLL- 618

Query: 778 PREFNSYGARRGNDAVMTRGTFANIKLFNKFIGKPAPKTIHFPSGQTLDVFEAAELYQKE 837
                  GA    +        A  + F      P P T              A  Y+K 
Sbjct: 619 ------IGAINIENGKANSVRNAVTQEFG-----PVPDT--------------ARYYKKH 653

Query: 838 GIPLIILAGKKYGSGNSRDWAAKGPYLLGVKAVLAESYEKIHKDHLIGIGIAPLQFLPGE 897
           GI  +++  + YG G+SR+ AA  P  LG +A++ +S+ +IH+ +L   G+ PL F   +
Sbjct: 654 GIRWVVIGDENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTF--AD 711

Query: 898 NADSLGLSGRETFSLTFPEELSPGITLN--IQTSTGKVFSVIASFE-DDVEITLYKHGGL 954
            AD   +   +  ++   ++ +PG  L   I+   G   +++ +   ++ +I  ++ G  
Sbjct: 712 PADYNKIHPVDKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSA 771

Query: 955 LN 956
           LN
Sbjct: 772 LN 773


>gi|239754889 PREDICTED: similar to hCG2036697 [Homo sapiens]
          Length = 1029

 Score = 31.2 bits (69), Expect = 4.9
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 833 LYQKEGIP--LIILAGKKYGSGNSRDWAAKGPYLLGVKAVL 871
           LY+ E +P  LI+   ++YG+ N R W   G +LL  KA+L
Sbjct: 748 LYRDETVPTSLILKGAEEYGTRN-RTWGTAGSFLLQKKAIL 787


>gi|239749428 PREDICTED: hypothetical protein XP_002347033 [Homo
           sapiens]
          Length = 1029

 Score = 31.2 bits (69), Expect = 4.9
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 833 LYQKEGIP--LIILAGKKYGSGNSRDWAAKGPYLLGVKAVL 871
           LY+ E +P  LI+   ++YG+ N R W   G +LL  KA+L
Sbjct: 748 LYRDETVPTSLILKGAEEYGTRN-RTWGTAGSFLLQKKAIL 787


>gi|239743562 PREDICTED: hypothetical protein XP_002342894 [Homo
           sapiens]
          Length = 1029

 Score = 31.2 bits (69), Expect = 4.9
 Identities = 17/41 (41%), Positives = 25/41 (60%), Gaps = 3/41 (7%)

Query: 833 LYQKEGIP--LIILAGKKYGSGNSRDWAAKGPYLLGVKAVL 871
           LY+ E +P  LI+   ++YG+ N R W   G +LL  KA+L
Sbjct: 748 LYRDETVPTSLILKGAEEYGTRN-RTWGTAGSFLLQKKAIL 787


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,122,442
Number of Sequences: 37866
Number of extensions: 1738930
Number of successful extensions: 3485
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3474
Number of HSP's gapped (non-prelim): 10
length of query: 963
length of database: 18,247,518
effective HSP length: 112
effective length of query: 851
effective length of database: 14,006,526
effective search space: 11919553626
effective search space used: 11919553626
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.