Guide to the Human Genome
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Search of human proteins with 41350330

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo
sapiens]
         (216 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo ...   458   e-129
gi|18677731 MOB-LAK [Homo sapiens]                                    379   e-105
gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isofor...   350   4e-97
gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isofor...   350   4e-97
gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo ...   251   4e-67
gi|148747437 Mob4B protein [Homo sapiens]                             249   1e-66
gi|34594669 HCCA2 protein [Homo sapiens]                              126   2e-29
gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [H...    55   3e-08
gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Ho...    52   5e-07
gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Ho...    52   5e-07

>gi|41350330 MOB1, Mps One Binder kinase activator-like 2B [Homo
           sapiens]
          Length = 216

 Score =  458 bits (1178), Expect = e-129
 Identities = 216/216 (100%), Positives = 216/216 (100%)

Query: 1   MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 60
           MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV
Sbjct: 1   MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 60

Query: 61  AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 120
           AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL
Sbjct: 61  AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 120

Query: 121 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 180
           LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA
Sbjct: 121 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 180

Query: 181 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216
           HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH
Sbjct: 181 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216


>gi|18677731 MOB-LAK [Homo sapiens]
          Length = 217

 Score =  379 bits (972), Expect = e-105
 Identities = 174/212 (82%), Positives = 193/212 (91%)

Query: 5   LKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHV 64
           LKQVFNKDKTFRPKRKFEPGTQRFELHK+AQASLN+G+DL+ AVQLP GED NDWVAVHV
Sbjct: 6   LKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDWVAVHV 65

Query: 65  VDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDW 124
           VDFFNR+NLIYGTI + CTE++CPVMSGGPKYEYRWQD+ K++KPTAL AP+YM+LLMDW
Sbjct: 66  VDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMDLLMDW 125

Query: 125 IEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNT 184
           IE QINNE++FPT VG PFPKNFLQ  +KIL RLFRVFVHVYIHHFDR+  MG+EAHVNT
Sbjct: 126 IEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSEAHVNT 185

Query: 185 CYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216
           CYKHFYYFV E  LID KELEPLKEMT+RMCH
Sbjct: 186 CYKHFYYFVKEFGLIDTKELEPLKEMTARMCH 217


>gi|41406059 MOB1, Mps One Binder kinase activator-like 2C isoform 1
           [Homo sapiens]
          Length = 268

 Score =  350 bits (899), Expect = 4e-97
 Identities = 155/216 (71%), Positives = 191/216 (88%)

Query: 1   MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 60
           M++ LKQVF KDKTFRP+++FEPGTQRFEL+K+AQASL SG+DL++ V+LP GE+ +DW+
Sbjct: 53  MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 112

Query: 61  AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 120
           AVHVVDFFNRINLIYGT+ E C+E +CPVM+GGP+YEYRWQD+ +Y++P  L AP+YM L
Sbjct: 113 AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 172

Query: 121 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 180
           LMDWIE  IN+EE+FPT VGVPFPKNF Q+C KIL RLFRVFVHVYIHHFD ++ MGAEA
Sbjct: 173 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 232

Query: 181 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216
           HVNTCYKHFYYF+ E +L+D++ELEPL+EMT R+CH
Sbjct: 233 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 268


>gi|41406061 MOB1, Mps One Binder kinase activator-like 2C isoform 2
           [Homo sapiens]
          Length = 216

 Score =  350 bits (899), Expect = 4e-97
 Identities = 155/216 (71%), Positives = 191/216 (88%)

Query: 1   MSIALKQVFNKDKTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWV 60
           M++ LKQVF KDKTFRP+++FEPGTQRFEL+K+AQASL SG+DL++ V+LP GE+ +DW+
Sbjct: 1   MALCLKQVFAKDKTFRPRKRFEPGTQRFELYKKAQASLKSGLDLRSVVRLPPGENIDDWI 60

Query: 61  AVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNL 120
           AVHVVDFFNRINLIYGT+ E C+E +CPVM+GGP+YEYRWQD+ +Y++P  L AP+YM L
Sbjct: 61  AVHVVDFFNRINLIYGTMAERCSETSCPVMAGGPRYEYRWQDERQYRRPAKLSAPRYMAL 120

Query: 121 LMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEA 180
           LMDWIE  IN+EE+FPT VGVPFPKNF Q+C KIL RLFRVFVHVYIHHFD ++ MGAEA
Sbjct: 121 LMDWIEGLINDEEVFPTRVGVPFPKNFQQVCTKILTRLFRVFVHVYIHHFDSILSMGAEA 180

Query: 181 HVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMCH 216
           HVNTCYKHFYYF+ E +L+D++ELEPL+EMT R+CH
Sbjct: 181 HVNTCYKHFYYFIREFSLVDQRELEPLREMTERICH 216


>gi|27735029 MOB1, Mps One Binder kinase activator-like 1A [Homo
           sapiens]
          Length = 216

 Score =  251 bits (640), Expect = 4e-67
 Identities = 112/202 (55%), Positives = 152/202 (75%), Gaps = 1/202 (0%)

Query: 13  KTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRIN 72
           KTF+PK+    G+ ++EL K A+A+L SG +L+ AV LP GED N+WVAV+ VDFFN+IN
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEWVAVNTVDFFNQIN 69

Query: 73  LIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNE 132
           ++YGTI +FCTE +CPVMS GPKYEY W D    KKP    AP+Y++ LM W++ Q+++E
Sbjct: 70  MLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 133 EIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYF 192
            +FP+ +GVPFPKNF+ + K IL RLFRV+ H+Y  HFD VI +  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEEAHLNTSFKHFIFF 189

Query: 193 VTEMNLIDRKELEPLKEMTSRM 214
           V E NLIDR+EL PL+E+  ++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|148747437 Mob4B protein [Homo sapiens]
          Length = 216

 Score =  249 bits (636), Expect = 1e-66
 Identities = 110/202 (54%), Positives = 152/202 (75%), Gaps = 1/202 (0%)

Query: 13  KTFRPKRKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRIN 72
           KTF+PK+    G+ ++EL K A+A+L SG +L+ AV LP GED N+W+AV+ VDFFN+IN
Sbjct: 11  KTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEWIAVNTVDFFNQIN 69

Query: 73  LIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNE 132
           ++YGTI EFCTE +CPVMS GP+YEY W D    KKP    AP+Y++ LM W++ Q+++E
Sbjct: 70  MLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYIDYLMTWVQDQLDDE 129

Query: 133 EIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYF 192
            +FP+ +GVPFPKNF+ + K IL RLFRV+ H+Y  HFD V+ +  EAH+NT +KHF +F
Sbjct: 130 TLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFF 189

Query: 193 VTEMNLIDRKELEPLKEMTSRM 214
           V E NLIDR+EL PL+E+  ++
Sbjct: 190 VQEFNLIDRRELAPLQELIEKL 211


>gi|34594669 HCCA2 protein [Homo sapiens]
          Length = 237

 Score =  126 bits (316), Expect = 2e-29
 Identities = 64/171 (37%), Positives = 92/171 (53%), Gaps = 3/171 (1%)

Query: 45  KAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDL 104
           K  V LP   D N+W+A +   FF+ INL Y TI EFCT  TC  M+     +Y W D+ 
Sbjct: 41  KELVVLPREIDLNEWLASNTTTFFHHINLQYSTISEFCTGETCQTMAVC-NTQYYWYDER 99

Query: 105 KYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVH 164
              K     APQY++ +M  ++  + +E++FPT  G  FP +F  + +KI   LF V  H
Sbjct: 100 G--KKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKYGREFPSSFESLVRKICRHLFHVLAH 157

Query: 165 VYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKELEPLKEMTSRMC 215
           +Y  HF   + +    H+NT Y HF  F  E NL+D KE   + ++T  +C
Sbjct: 158 IYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKETAIMDDLTEVLC 208


>gi|155030224 Mps One Binder kinase activator-like 3 isoform 3 [Homo
           sapiens]
          Length = 204

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 43/186 (23%), Positives = 82/186 (44%), Gaps = 11/186 (5%)

Query: 19  RKFEPGTQRFELHKRAQASLNSGVDLKAAVQLPSGEDQNDWVAVHVVDFFNRINLIYGTI 78
           R+  PGT+   + +  +A  ++   +   ++ P G+D+  W   H+  F   +N +   +
Sbjct: 11  RRNRPGTKAQYIQQNIRADCSN---IDKILEPPEGQDEGVWKYEHLRQFCLELNGLAVKL 67

Query: 79  CEFCTERTCPVMSGGPKYEYRWQDDLKYKKPTALPAPQYMNLLMDWIEVQINNEEIFPTC 138
              C   TC  M+   ++ +       +K P   PA  Y    +D     +N+ + FP+ 
Sbjct: 68  QSECHPDTCTQMTATEQWIFLCA---AHKTPKECPAIDYTRHTLDGAACLLNSNKYFPSR 124

Query: 139 VGVPFPKNFLQICKKILCRLFRVFVHVYIHHFDRVIVMGAEAHVNTCYKHFYYFVTEMNL 198
           V +   ++ +     +  R++R+F H Y HH  R I    E     C++ F  FV + NL
Sbjct: 125 VSIK--ESSVAKLGSVCRRIYRIFSHAYFHH--RQIFDEYENETFLCHR-FTKFVMKYNL 179

Query: 199 IDRKEL 204
           + +  L
Sbjct: 180 MSKDNL 185


>gi|41349451 Mps One Binder kinase activator-like 3 isoform 2 [Homo
           sapiens]
          Length = 193

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 8/154 (5%)

Query: 51  PSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPT 110
           P G+D+  W   H+  F   +N +   +   C   TC  M+   ++ +       +K P 
Sbjct: 29  PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA---AHKTPK 85

Query: 111 ALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHF 170
             PA  Y    +D     +N+ + FP+ V +   ++ +     +  R++R+F H Y HH 
Sbjct: 86  ECPAIDYTRHTLDGAACLLNSNKYFPSRVSIK--ESSVAKLGSVCRRIYRIFSHAYFHH- 142

Query: 171 DRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKEL 204
            R I    E     C++ F  FV + NL+ +  L
Sbjct: 143 -RQIFDEYENETFLCHR-FTKFVMKYNLMSKDNL 174


>gi|41349449 Mps One Binder kinase activator-like 3 isoform 1 [Homo
           sapiens]
          Length = 225

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 38/154 (24%), Positives = 67/154 (43%), Gaps = 8/154 (5%)

Query: 51  PSGEDQNDWVAVHVVDFFNRINLIYGTICEFCTERTCPVMSGGPKYEYRWQDDLKYKKPT 110
           P G+D+  W   H+  F   +N +   +   C   TC  M+   ++ +       +K P 
Sbjct: 61  PEGQDEGVWKYEHLRQFCLELNGLAVKLQSECHPDTCTQMTATEQWIFLCA---AHKTPK 117

Query: 111 ALPAPQYMNLLMDWIEVQINNEEIFPTCVGVPFPKNFLQICKKILCRLFRVFVHVYIHHF 170
             PA  Y    +D     +N+ + FP+ V +   ++ +     +  R++R+F H Y HH 
Sbjct: 118 ECPAIDYTRHTLDGAACLLNSNKYFPSRVSIK--ESSVAKLGSVCRRIYRIFSHAYFHH- 174

Query: 171 DRVIVMGAEAHVNTCYKHFYYFVTEMNLIDRKEL 204
            R I    E     C++ F  FV + NL+ +  L
Sbjct: 175 -RQIFDEYENETFLCHR-FTKFVMKYNLMSKDNL 206


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,737,370
Number of Sequences: 37866
Number of extensions: 394318
Number of successful extensions: 858
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 842
Number of HSP's gapped (non-prelim): 10
length of query: 216
length of database: 18,247,518
effective HSP length: 98
effective length of query: 118
effective length of database: 14,536,650
effective search space: 1715324700
effective search space used: 1715324700
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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