Search of human proteins with 40068518

Search of human proteins with 40068518

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]
         (483 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]             980   0.0  
gi|23308751 3-hydroxyisobutyrate dehydrogenase [Homo sapiens]          40   0.005
gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]          37   0.052
gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]                    32   1.3  
gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]                   32   1.3  
gi|23199991 casein kinase 1 epsilon [Homo sapiens]                     30   3.7  
gi|4503093 casein kinase 1 epsilon [Homo sapiens]                      30   3.7  
gi|16579828 zinc finger protein 91 [Homo sapiens]                      30   4.9  

>gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]
          Length = 483

 Score =  980 bits (2534), Expect = 0.0
 Identities = 483/483 (100%), Positives = 483/483 (100%)

Query: 1   MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE 60
           MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE
Sbjct: 1   MAQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKE 60

Query: 61  MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG 120
           MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG
Sbjct: 61  MVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKG 120

Query: 121 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 180
           ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG
Sbjct: 121 ILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 180

Query: 181 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL 240
           HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL
Sbjct: 181 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANIL 240

Query: 241 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA 300
           KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA
Sbjct: 241 KFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQA 300

Query: 301 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL 360
           SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL
Sbjct: 301 SKKLKGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIAL 360

Query: 361 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM 420
           MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM
Sbjct: 361 MWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPM 420

Query: 421 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS 480
           PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS
Sbjct: 421 PCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPGQFIHTNWTGHGGTVSSSS 480

Query: 481 YNA 483
           YNA
Sbjct: 481 YNA 483


>gi|23308751 3-hydroxyisobutyrate dehydrogenase [Homo sapiens]
          Length = 336

 Score = 40.0 bits (92), Expect = 0.005
 Identities = 40/191 (20%), Positives = 80/191 (41%), Gaps = 19/191 (9%)

Query: 2   AQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEM 61
           ++  +  IGL  MG  +  N+  HG+ +  +        D   +  K  +  G Q +   
Sbjct: 38  SKTPVGFIGLGNMGNPMAKNLMKHGYPLIIY--------DVFPDACKEFQDAGEQVVSSP 89

Query: 62  VSKLKKPRRIILLVKAG-QAVDDF--IEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKA 118
               +K  RII ++     A++ +     ++  +  G ++ID    +   +    ++++ 
Sbjct: 90  ADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEK 149

Query: 119 KGILFVGSGVSGGEEGARYGP-SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDE 177
            G +F+ + VSGG   AR G  + M GG ++ +       Q +   +G+    C   G  
Sbjct: 150 MGAVFMDAPVSGGVGAARSGNLTFMVGGVEDEF----AAAQELLGCMGSNVVYC---GAV 202

Query: 178 GAGHFVKMVHN 188
           G G   K+ +N
Sbjct: 203 GTGQAAKICNN 213


>gi|40556376 cytokine-like nuclear factor n-pac [Homo sapiens]
          Length = 553

 Score = 36.6 bits (83), Expect = 0.052
 Identities = 50/242 (20%), Positives = 100/242 (41%), Gaps = 26/242 (10%)

Query: 6   IALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAK----GTKVVGAQSLKEM 61
           I  +GL +MG  ++ N+   G  V  +NRT  K D F+   A+      +VV    +   
Sbjct: 270 IGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFA 329

Query: 62  VSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGI 121
                K  + ++L  +G         ++  +  G   +D    +    T   + + ++G 
Sbjct: 330 CVSDPKAAKDLVLGPSG---------VLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGG 380

Query: 122 LFVGSGVSGGEEGARYGP-SLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGAG 180
            F+ + VSG ++ +  G   ++  G++  +    + FQ +            ++G+ G  
Sbjct: 381 RFLEAPVSGNQQLSNDGMLVILAAGDRGLYEDCSSCFQAMG-------KTSFFLGEVGNA 433

Query: 181 HFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDS-FLIEITANI 239
             + ++ N ++   M  I E   L + V G +Q  +       N+ +L S FL +   NI
Sbjct: 434 AKMMLIVNMVQGSFMATIAEGLTLAQ-VTGQSQQTLLDIL---NQGQLASIFLDQKCQNI 489

Query: 240 LK 241
           L+
Sbjct: 490 LQ 491


>gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]
          Length = 417

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 26/135 (19%)

Query: 31  AFNRTVSKVDDFLANEAKGT------KVVGA------------QSLKEMVSKLKKPRRII 72
           AF  ++SK+ D   N+A GT       +VG             + L      L+ P R  
Sbjct: 149 AFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPF 208

Query: 73  LLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGE 132
           L +  G  V D I+ +  +LD  + +I GG   +         LK    + +G+ +   E
Sbjct: 209 LAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF-------TFLKVLNNMEIGTSLF-DE 260

Query: 133 EGARYGPSLMPGGNK 147
           EGA+    LM    K
Sbjct: 261 EGAKIVKDLMSKAEK 275


>gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]
          Length = 417

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 26/135 (19%)

Query: 31  AFNRTVSKVDDFLANEAKGT---------------KVVGAQSLKEM---VSKLKKPRRII 72
           AF  ++SK+ D   N+A GT               K  G    KE+      L+ P R  
Sbjct: 149 AFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPHKASGFLMKKELDYFAKALENPVRPF 208

Query: 73  LLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGE 132
           L +  G  V D I+ +  +LD  + +I GG   Y         LK    + +G+ +   E
Sbjct: 209 LAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAY-------TFLKVLNNMEIGASLF-DE 260

Query: 133 EGARYGPSLMPGGNK 147
           EGA+    +M    K
Sbjct: 261 EGAKIVKDIMAKAQK 275


>gi|23199991 casein kinase 1 epsilon [Homo sapiens]
          Length = 416

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 120 GILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGA 179
           G +++G+ ++ GEE A     L     K    HI++ F  +  + G G P   W G EG 
Sbjct: 21  GDIYLGANIASGEEVAI---KLECVKTKHPQLHIESKFYKMM-QGGVGIPSIKWCGAEGD 76

Query: 180 GHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFE 221
            + + M   G    D+   C     +K VL +A D+M    E
Sbjct: 77  YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA-DQMISRIE 117


>gi|4503093 casein kinase 1 epsilon [Homo sapiens]
          Length = 416

 Score = 30.4 bits (67), Expect = 3.7
 Identities = 29/102 (28%), Positives = 45/102 (44%), Gaps = 5/102 (4%)

Query: 120 GILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGTGEPCCDWVGDEGA 179
           G +++G+ ++ GEE A     L     K    HI++ F  +  + G G P   W G EG 
Sbjct: 21  GDIYLGANIASGEEVAI---KLECVKTKHPQLHIESKFYKMM-QGGVGIPSIKWCGAEGD 76

Query: 180 GHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFE 221
            + + M   G    D+   C     +K VL +A D+M    E
Sbjct: 77  YNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLA-DQMISRIE 117


>gi|16579828 zinc finger protein 91 [Homo sapiens]
          Length = 570

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 17/35 (48%), Positives = 20/35 (57%), Gaps = 1/35 (2%)

Query: 100 DGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEG 134
           +G +  Y   T R   L A G +FVGSG SGG EG
Sbjct: 513 EGMSKSYCSGTERV-SLMADGKIFVGSGSSGGTEG 546


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,875,059
Number of Sequences: 37866
Number of extensions: 794657
Number of successful extensions: 1675
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1672
Number of HSP's gapped (non-prelim): 8
length of query: 483
length of database: 18,247,518
effective HSP length: 106
effective length of query: 377
effective length of database: 14,233,722
effective search space: 5366113194
effective search space used: 5366113194
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.