Search of human proteins with 37537527

Search of human proteins with 37537527

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|37537527 monoacylglycerol O-acyltransferase 2 [Homo sapiens]
         (334 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|37537527 monoacylglycerol O-acyltransferase 2 [Homo sapiens]       689   0.0  
gi|148746191 monoacylglycerol O-acyltransferase 1 [Homo sapiens]      380   e-106
gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens]         325   3e-89
gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens]       303   2e-82
gi|61888902 wax synthase 1 [Homo sapiens]                             290   9e-79
gi|38348340 diacylglycerol O-acyltransferase 2-like 6 [Homo sapi...   285   4e-77
gi|51317389 wax synthase 2 [Homo sapiens]                             281   4e-76
gi|156231067 TBC1 domain family, member 8 [Homo sapiens]               30   3.9  

>gi|37537527 monoacylglycerol O-acyltransferase 2 [Homo sapiens]
          Length = 334

 Score =  689 bits (1778), Expect = 0.0
 Identities = 334/334 (100%), Positives = 334/334 (100%)

Query: 1   MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLD 60
           MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLD
Sbjct: 1   MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLD 60

Query: 61  RDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFAN 120
           RDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFAN
Sbjct: 61  RDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFAN 120

Query: 121 LCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNL 180
           LCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNL
Sbjct: 121 LCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNL 180

Query: 181 LGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG 240
           LGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG
Sbjct: 181 LGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSG 240

Query: 241 SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEE 300
           SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEE
Sbjct: 241 SWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEE 300

Query: 301 VNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC 334
           VNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC
Sbjct: 301 VNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC 334


>gi|148746191 monoacylglycerol O-acyltransferase 1 [Homo sapiens]
          Length = 335

 Score =  380 bits (976), Expect = e-106
 Identities = 177/330 (53%), Positives = 239/330 (72%)

Query: 2   VEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDR 61
           VEFAPL +   RRLQT+AVLQ+V  +L L  +     + L+   +  L + Y  W Y D 
Sbjct: 3   VEFAPLNIQLARRLQTVAVLQWVLKYLLLGPMSIGITVMLIIHNYLFLYIPYLMWLYFDW 62

Query: 62  DKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANL 121
             P +GGR    I+ WT+WK+ KDYFPI L+KT +LDPS NYI GFHPHG++AVGAF N 
Sbjct: 63  HTPERGGRRSSWIKNWTLWKHFKDYFPIHLIKTQDLDPSHNYIFGFHPHGIMAVGAFGNF 122

Query: 122 CTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLL 181
               + F  +FPG   +L +L LWF  P FR+Y+MS GLV+  K+S +++++++GGGN+ 
Sbjct: 123 SVNYSDFKDLFPGFTSYLHVLPLWFWCPVFREYVMSVGLVSVSKKSVSYMVSKEGGGNIS 182

Query: 182 GIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGS 241
            I++GGA+E+LDA PG FTL +R RKGFV++ALTHGA LVP+ SFGEN+LF Q  N  GS
Sbjct: 183 VIVLGGAKESLDAHPGKFTLFIRQRKGFVKIALTHGASLVPVVSFGENELFKQTDNPEGS 242

Query: 242 WLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEV 301
           W+R +QN+LQKIMG +LPLFH RGVFQY+FGL+ YR+ I TVVG+PI V++TL+P++E++
Sbjct: 243 WIRTVQNKLQKIMGFALPLFHARGVFQYNFGLMTYRKAIHTVVGRPIPVRQTLNPTQEQI 302

Query: 302 NQLHQRYIKELCNLFEAHKLKFNIPADQHL 331
            +LHQ Y++EL  LFE HK K+ IP  + L
Sbjct: 303 EELHQTYMEELRKLFEEHKGKYGIPEHETL 332


>gi|26024197 diacylglycerol O-acyltransferase 2 [Homo sapiens]
          Length = 388

 Score =  325 bits (833), Expect = 3e-89
 Identities = 151/322 (46%), Positives = 219/322 (68%), Gaps = 1/322 (0%)

Query: 12  ERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHI 71
           E++LQ ++VLQ+V SFL L   C+   + +  T  WL+ VLY  W   D + P++GGR  
Sbjct: 65  EKQLQVISVLQWVLSFLVLGVACSAILMYIFCTDCWLIAVLYFTWLVFDWNTPKKGGRRS 124

Query: 72  QAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSI 131
           Q +R W +W+Y +DYFPI LVKT  L  +RNYI G+HPHG++ +GAF N  TE+T  S  
Sbjct: 125 QWVRNWAVWRYFRDYFPIQLVKTHNLLTTRNYIFGYHPHGIMGLGAFCNFSTEATEVSKK 184

Query: 132 FPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEA 191
           FPGIRP+L  L   FR P  R+Y+MS G+    +++  ++L++ G GN + I+VGGA E+
Sbjct: 185 FPGIRPYLATLAGNFRMPVLREYLMSGGICPVSRDTIDYLLSKNGSGNAIIIVVGGAAES 244

Query: 192 LDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQ 251
           L + PG   + LRNRKGFV+LAL HGA LVPI+SFGEN+++ Q+    GSW R++Q + Q
Sbjct: 245 LSSMPGKNAVTLRNRKGFVKLALRHGADLVPIYSFGENEVYKQVIFEEGSWGRWVQKKFQ 304

Query: 252 KIMGISLPLFHGRGVFQY-SFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIK 310
           K +G +  +FHGRG+F   ++GL+PY +PITTVVG+PI + K  HP++++++  H  Y++
Sbjct: 305 KYIGFAPCIFHGRGLFSSDTWGLVPYSKPITTVVGEPITIPKLEHPTQQDIDLYHTMYME 364

Query: 311 ELCNLFEAHKLKFNIPADQHLE 332
            L  LF+ HK KF +P  + LE
Sbjct: 365 ALVKLFDKHKTKFGLPETEVLE 386


>gi|30039700 monoacylglycerol O-acyltransferase 3 [Homo sapiens]
          Length = 341

 Score =  303 bits (775), Expect = 2e-82
 Identities = 154/323 (47%), Positives = 204/323 (63%), Gaps = 1/323 (0%)

Query: 12  ERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHI 71
           ++ L+ +   Q+V +FL +    ++    LLFT  W  +V Y  W Y+D D P QGGR  
Sbjct: 18  KQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRRS 77

Query: 72  QAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSI 131
           + IR   IW+ ++DY+P+ LVKTAEL P RNY+ G HPHG++  G   N  TES GFS +
Sbjct: 78  EWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQL 137

Query: 132 FPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEA 191
           FPG+RP L +L   F  P +RDYIMS GL    ++S   IL++   G  + I+VGGA EA
Sbjct: 138 FPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHEA 197

Query: 192 LDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQ 251
           L + PG   L L+ RKGFVRLAL HGA LVP++SFGEND+F     ++GSW  + Q   +
Sbjct: 198 LYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFK 257

Query: 252 KIMGISLPLFHGRGVFQ-YSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIK 310
           K+MG S  +F GRG+F   S+GL+P+  PITTVVG+PI V + LHP+EEEVN  H  Y+ 
Sbjct: 258 KLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYHALYMT 317

Query: 311 ELCNLFEAHKLKFNIPADQHLEF 333
            L  LFE HK    +PA   L F
Sbjct: 318 ALEQLFEEHKESCGVPASTCLTF 340


>gi|61888902 wax synthase 1 [Homo sapiens]
          Length = 328

 Score =  290 bits (743), Expect = 9e-79
 Identities = 146/318 (45%), Positives = 203/318 (63%), Gaps = 1/318 (0%)

Query: 16  QTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHIQAIR 75
           Q+L +LQ+  S+LA+  I    F+ LLFT  W L VLY AW +LD   P +GGR    +R
Sbjct: 11  QSLMLLQWPLSYLAIFWILQPLFVYLLFTSLWPLPVLYFAWLFLDWKTPERGGRRSAWVR 70

Query: 76  CWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSIFPGI 135
            W +W +++DYFPI+++KT +L P  NY+ G HPHG+L  GAF N CTE+TGFS  FPGI
Sbjct: 71  NWCVWTHIRDYFPITILKTKDLSPEHNYLMGVHPHGLLTFGAFCNFCTEATGFSKTFPGI 130

Query: 136 RPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEALDAR 195
            PHL  L+ +F+ PF R+Y+M+ G V S  + A + L   G GNL+GI+VGG  EAL + 
Sbjct: 131 TPHLATLSWFFKIPFVREYLMAKG-VCSVSQPAINYLLSHGTGNLVGIVVGGVGEALQSV 189

Query: 196 PGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQKIMG 255
           P + TL+L+ RKGFVR AL HGA LVP F+FGE +++DQ+     S +   Q+  ++I G
Sbjct: 190 PNTTTLILQKRKGFVRTALQHGAHLVPTFTFGETEVYDQVLFHKDSRMYKFQSCFRRIFG 249

Query: 256 ISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIKELCNL 315
               +F+G+   Q S GL+PY RPI TVVG+P+ + +   PS+E V++ H  Y+  L  L
Sbjct: 250 FYCCVFYGQSFCQGSTGLLPYSRPIVTVVGEPLPLPQIEKPSQEMVDKYHALYMDALHKL 309

Query: 316 FEAHKLKFNIPADQHLEF 333
           F+ HK  +     Q L F
Sbjct: 310 FDQHKTHYGCSETQKLFF 327


>gi|38348340 diacylglycerol O-acyltransferase 2-like 6 [Homo
           sapiens]
          Length = 337

 Score =  285 bits (729), Expect = 4e-77
 Identities = 145/323 (44%), Positives = 202/323 (62%), Gaps = 7/323 (2%)

Query: 15  LQTLAVLQF--VFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHIQ 72
           LQT  VLQ+  V+ FL    I  + +  LLF++FW L VL  AW   D +   QGGR   
Sbjct: 13  LQTFFVLQWIPVYIFLGAIPILLIPYF-LLFSKFWPLAVLSLAWLTYDWNTHSQGGRRSA 71

Query: 73  AIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSIF 132
            +R WT+WKY ++YFP+ LVKT +L P  NYI   HPHG+L+ G F N  TE+TG + IF
Sbjct: 72  WVRNWTLWKYFRNYFPVKLVKTHDLSPKHNYIIANHPHGILSFGVFINFATEATGIARIF 131

Query: 133 PGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEAL 192
           P I P +  L   F  P  R+Y+MS G+      +  ++L +KG GN + I+VGGA EAL
Sbjct: 132 PSITPFVGTLERIFWIPIVREYVMSMGVCPVSSSALKYLLTQKGSGNAVVIVVGGAAEAL 191

Query: 193 DARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQ- 251
             RPG+ TL L+ RKGFV++AL  GA LVP +SFGEN++F+Q     G+WLR  Q   Q 
Sbjct: 192 LCRPGASTLFLKQRKGFVKMALQTGAYLVPSYSFGENEVFNQETFPEGTWLRLFQKTFQD 251

Query: 252 ---KIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRY 308
              KI+G++   FHGRG  + S+G +P+ RPITTVVG+P+ + +   P+++ V++ H  Y
Sbjct: 252 TFKKILGLNFCTFHGRGFTRGSWGFLPFNRPITTVVGEPLPIPRIKRPNQKTVDKYHALY 311

Query: 309 IKELCNLFEAHKLKFNIPADQHL 331
           I  L  LF+ HK+++ +P  Q L
Sbjct: 312 ISALRKLFDQHKVEYGLPETQEL 334


>gi|51317389 wax synthase 2 [Homo sapiens]
          Length = 333

 Score =  281 bits (720), Expect = 4e-76
 Identities = 138/319 (43%), Positives = 198/319 (62%), Gaps = 1/319 (0%)

Query: 15  LQTLAVLQFVFSFLALAE-ICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHIQA 73
           L   AV Q+ FS L +   +  V    ++FT +W +TVL   W   D   P++GGR    
Sbjct: 13  LDVFAVFQWSFSALLITTTVIAVNLYLVVFTPYWPVTVLILTWLAFDWKTPQRGGRRFTC 72

Query: 74  IRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSIFP 133
           +R W +WK+  DYFP+ L+KT ++ PSRNYI   HPHG+ A G F +  TE++GFS IFP
Sbjct: 73  VRHWRLWKHYSDYFPLKLLKTHDICPSRNYILVCHPHGLFAHGWFGHFATEASGFSKIFP 132

Query: 134 GIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEALD 193
           GI P+++ L  +F  PF R+Y+MS G  +  + S   +L  KG GN++ +++GG  E   
Sbjct: 133 GITPYILTLGAFFWMPFLREYVMSTGACSVSRSSIDFLLTHKGTGNMVIVVIGGLAECRY 192

Query: 194 ARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQKI 253
           + PGS TL+L+NR GFVR+AL HG PL+P ++FGE DL+DQ   + G ++   Q   Q +
Sbjct: 193 SLPGSSTLVLKNRSGFVRMALQHGVPLIPAYAFGETDLYDQHIFTPGGFVNRFQKWFQSM 252

Query: 254 MGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIKELC 313
           + I    F+GRG  + S+GL+PY RP+TT+VG+P+ + K  +PS+E V + H  YI  L 
Sbjct: 253 VHIYPCAFYGRGFTKNSWGLLPYSRPVTTIVGEPLPMPKIENPSQEIVAKYHTLYIDALR 312

Query: 314 NLFEAHKLKFNIPADQHLE 332
            LF+ HK KF I   Q LE
Sbjct: 313 KLFDQHKTKFGISETQELE 331


>gi|156231067 TBC1 domain family, member 8 [Homo sapiens]
          Length = 1140

 Score = 29.6 bits (65), Expect = 3.9
 Identities = 47/180 (26%), Positives = 66/180 (36%), Gaps = 44/180 (24%)

Query: 160 LVTSEKESAAHILNRK-----GGGNLLGIIVGGAQEALD--ARPGSFTLLLRNRKGFVRL 212
           L  ++K S   IL R+     GGG L G +VG     LD  AR   F +LL+     V  
Sbjct: 16  LWVTQKSSCYFILQRRRGHGEGGGRLTGRLVGALDAVLDSNARVAPFRILLQVPGSQVYS 75

Query: 213 ALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQKIMGISLPLFHGRGVFQYSFG 272
            +  GA L  I             N    WL   QN           L H   VF     
Sbjct: 76  PIACGATLEEI-------------NQHWDWLE--QN-----------LLHTLSVFDNKDD 109

Query: 273 LIPY-RRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIKELCNLFEAHKLKFNIPADQHL 331
           +  + +  +  ++ +  E    L   EEE  +  +  +K     FEA   +FN P  + L
Sbjct: 110 IASFVKGKVKALIAE--ETSSRLAEQEEEPEKFREALVK-----FEA---RFNFPEAEKL 159


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,926,077
Number of Sequences: 37866
Number of extensions: 576951
Number of successful extensions: 1346
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1335
Number of HSP's gapped (non-prelim): 8
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.