Guide to the Human Genome
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Search of human proteins with 31543397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]                  830   0.0  
gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]                   744   0.0  
gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]              32   1.1  
gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]           30   3.1  
gi|24308251 bile acid beta-glucosidase [Homo sapiens]                  29   6.9  
gi|9558729 golgi associated, gamma adaptin ear containing, ARF b...    29   6.9  
gi|48527952 golgi associated, gamma adaptin ear containing, ARF ...    29   6.9  

>gi|31543397 phosphoglycerate kinase 2 [Homo sapiens]
          Length = 417

 Score =  830 bits (2144), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL 60
           MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL
Sbjct: 1   MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL 60

Query: 61  MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE 120
           MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE
Sbjct: 61  MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE 120

Query: 121 NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180
           NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
Sbjct: 121 NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180

Query: 181 LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM 240
           LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM
Sbjct: 181 LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM 240

Query: 241 AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK 300
           AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK
Sbjct: 241 AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK 300

Query: 301 ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV 360
           ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV
Sbjct: 301 ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV 360

Query: 361 KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM 417
           KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM
Sbjct: 361 KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM 417


>gi|4505763 phosphoglycerate kinase 1 [Homo sapiens]
          Length = 417

 Score =  744 bits (1922), Expect = 0.0
 Identities = 364/417 (87%), Positives = 395/417 (94%)

Query: 1   MSLSKKLTLDKLDVRGKRVIMRVDFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKAVVL 60
           MSLS KLTLDKLDV+GKRV+MRVDFNVPMK NQITNNQRIKA++PSIK+CLDNGAK+VVL
Sbjct: 1   MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVL 60

Query: 61  MSHLGRPDGVPMPDKYSLAPVAVELKSLLGKDVLFLKDCVGAEVEKACANPAPGSVILLE 120
           MSHLGRPDGVPMPDKYSL PVAVELKSLLGKDVLFLKDCVG EVEKACANPA GSVILLE
Sbjct: 61  MSHLGRPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLE 120

Query: 121 NLRFHVEEEGKGQDPSGKKIKAEPDKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180
           NLRFHVEEEGKG+D SG K+KAEP KIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN
Sbjct: 121 NLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVN 180

Query: 181 LPHKASGFLMKKELDYFAKALENPVRPFLAILGGAKVADKIQLIKNMLDKVNEMIIGGGM 240
           LP KA GFLMKKEL+YFAKALE+P RPFLAILGGAKVADKIQLI NMLDKVNEMIIGGGM
Sbjct: 181 LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM 240

Query: 241 AYTFLKVLNNMEIGASLFDEEGAKIVKDIMAKAQKNGVRITFPVDFVTGDKFDENAQVGK 300
           A+TFLKVLNNMEIG SLFDEEGAKIVKD+M+KA+KNGV+IT PVDFVT DKFDENA+ G+
Sbjct: 241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQ 300

Query: 301 ATVASGISPGWMGLDCGPESNKNHAQVVAQARLIVWNGPLGVFEWDAFAKGTKALMDEIV 360
           ATVASGI  GWMGLDCGPES+K +A+ V +A+ IVWNGP+GVFEW+AFA+GTKALMDE+V
Sbjct: 301 ATVASGIPAGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVV 360

Query: 361 KATSKGCITVIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKILPGVEALSNM 417
           KATS+GCIT+IGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGK+LPGV+ALSN+
Sbjct: 361 KATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEGKVLPGVDALSNI 417


>gi|40068518 phosphogluconate dehydrogenase [Homo sapiens]
          Length = 483

 Score = 32.0 bits (71), Expect = 1.1
 Identities = 36/135 (26%), Positives = 54/135 (40%), Gaps = 26/135 (19%)

Query: 149 AFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPHKASGFLMKKELDYFAKALENPVRPF 208
           AF  ++SK+ D   N+A GT               K  G    KE+      L+ P R  
Sbjct: 31  AFNRTVSKVDDFLANEAKGT---------------KVVGAQSLKEM---VSKLKKPRRII 72

Query: 209 LAILGGAKVADKIQLIKNMLDKVNEMIIGGGMAY-------TFLKVLNNMEIGASLF-DE 260
           L +  G  V D I+ +  +LD  + +I GG   Y         LK    + +G+ +   E
Sbjct: 73  LLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGE 132

Query: 261 EGAKIVKDIMAKAQK 275
           EGA+    +M    K
Sbjct: 133 EGARYGPSLMPGGNK 147


>gi|23510451 N-acylaminoacyl-peptide hydrolase [Homo sapiens]
          Length = 732

 Score = 30.4 bits (67), Expect = 3.1
 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 130 GKGQDPSGKKIKAEPDKIEAFRAS-LSKLGDVYVNDAFGTAHRAHSS----MVGVNLPHK 184
           G G++    ++  +  K+++F  S L K G VY +D FG    +HS      V      K
Sbjct: 113 GPGEEKQFLEVWEKNRKLKSFNLSALEKHGPVYEDDCFGCLSWSHSETHLLYVAEKKRPK 172

Query: 185 ASGFLMKKELDYFA 198
           A  F   K LD  A
Sbjct: 173 AESFFQTKALDVSA 186


>gi|24308251 bile acid beta-glucosidase [Homo sapiens]
          Length = 927

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 16/39 (41%), Positives = 22/39 (56%), Gaps = 4/39 (10%)

Query: 339 PLGVFEWDAFAKGTKALMDEIVKATSKGCITVIGGGDTA 377
           P+GVF WD   +G +AL   I+ +   G    +GGGD A
Sbjct: 267 PVGVFVWDVENEGDEALDVSIMFSMRNG----LGGGDDA 301


>gi|9558729 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 2   SLSKKLTLDKLDVRGKRVIMRV----DFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKA 57
           SL     LD LD+ GK ++ +        V  +K Q T    ++        C    + A
Sbjct: 413 SLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSA 472

Query: 58  VVLMSHLG----RPDGVPMPDKYSLAPVAVELKSLLGKDVL 94
             L+  +     RP   P+P + SLA + V L+S+   ++L
Sbjct: 473 TSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPSNIL 513


>gi|48527952 golgi associated, gamma adaptin ear containing, ARF
           binding protein 1 isoform 2 [Homo sapiens]
          Length = 552

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 26/101 (25%), Positives = 43/101 (42%), Gaps = 8/101 (7%)

Query: 2   SLSKKLTLDKLDVRGKRVIMRV----DFNVPMKKNQITNNQRIKASIPSIKYCLDNGAKA 57
           SL     LD LD+ GK ++ +        V  +K Q T    ++        C    + A
Sbjct: 326 SLPASSGLDDLDLLGKTLLQQSLPPESQQVRWEKQQPTPRLTLRDLQNKSSSCSSPSSSA 385

Query: 58  VVLMSHLG----RPDGVPMPDKYSLAPVAVELKSLLGKDVL 94
             L+  +     RP   P+P + SLA + V L+S+   ++L
Sbjct: 386 TSLLHTVSPEPPRPPQQPVPTELSLASITVPLESIKPSNIL 426


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,308,123
Number of Sequences: 37866
Number of extensions: 684381
Number of successful extensions: 1455
Number of sequences better than 10.0: 7
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1451
Number of HSP's gapped (non-prelim): 9
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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