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Search of human proteins with 29171702
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor
[Homo sapiens]
(334 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Hom... 698 0.0
gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Hom... 650 0.0
gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Hom... 617 e-177
gi|11056044 pyrophosphatase 1 [Homo sapiens] 385 e-107
gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Hom... 330 1e-90
gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Hom... 246 3e-65
gi|57165424 cullin 4A isoform 1 [Homo sapiens] 30 2.3
gi|11140811 cullin 4A isoform 2 [Homo sapiens] 30 2.3
gi|221316749 carboxypeptidase A3 precursor [Homo sapiens] 30 3.9
gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 29 5.2
gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform ... 29 5.2
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 28 8.8
>gi|29171702 inorganic pyrophosphatase 2 isoform 1 precursor [Homo
sapiens]
Length = 334
Score = 698 bits (1802), Expect = 0.0
Identities = 334/334 (100%), Positives = 334/334 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
Query: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 180
VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC
Sbjct: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 180
Query: 181 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 240
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
Sbjct: 181 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 240
Query: 241 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 300
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
Sbjct: 241 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 300
Query: 301 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 301 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
>gi|77812684 inorganic pyrophosphatase 2 isoform 5 precursor [Homo
sapiens]
Length = 316
Score = 650 bits (1676), Expect = 0.0
Identities = 316/334 (94%), Positives = 316/334 (94%), Gaps = 18/334 (5%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
SPFHDIPLKVNSKEENGIPMKKARNDEYE IATKEPMNPIKQY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYE------------------IATKEPMNPIKQY 102
Query: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 180
VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC
Sbjct: 103 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 162
Query: 181 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 240
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
Sbjct: 163 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 222
Query: 241 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 300
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
Sbjct: 223 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 282
Query: 301 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 283 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 316
>gi|77812678 inorganic pyrophosphatase 2 isoform 2 precursor [Homo
sapiens]
Length = 305
Score = 617 bits (1591), Expect = e-177
Identities = 305/334 (91%), Positives = 305/334 (91%), Gaps = 29/334 (8%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY
Sbjct: 61 SPFHDIPLKVNSKEENGIPMKKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNPIKQY 120
Query: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFGDNDPIDVCEIGSKILSC 180
VKDGKLRYVANIFPYKGYIWNYGTLPQ ILSC
Sbjct: 121 VKDGKLRYVANIFPYKGYIWNYGTLPQ-----------------------------ILSC 151
Query: 181 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 240
GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL
Sbjct: 152 GEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFRL 211
Query: 241 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 300
YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF
Sbjct: 212 YKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQISDSPF 271
Query: 301 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 272 RCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 305
>gi|11056044 pyrophosphatase 1 [Homo sapiens]
Length = 289
Score = 385 bits (990), Expect = e-107
Identities = 176/283 (62%), Positives = 223/283 (78%), Gaps = 17/283 (6%)
Query: 32 MALYHTEERGQPCSQNYRLFFKNVTGHYISPFHDIPLKVNSKEENGIPMKKARNDEYENL 91
M+ + TEER P S YR+F KN G YISPFHDIP+ + +++
Sbjct: 1 MSGFSTEERAAPFSLEYRVFLKNEKGQYISPFHDIPIYAD-----------------KDV 43
Query: 92 FNMIVEIPRWTNAKMEIATKEPMNPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWED 151
F+M+VE+PRW+NAKMEIATK+P+NPIKQ VK GKLRYVAN+FPYKGYIWNYG +PQTWED
Sbjct: 44 FHMVVEVPRWSNAKMEIATKDPLNPIKQDVKKGKLRYVANLFPYKGYIWNYGAIPQTWED 103
Query: 152 PHEKDKSTNCFGDNDPIDVCEIGSKILSCGEVIHVKILGILALIDEGETDWKLIAINAND 211
P DK T C GDNDPIDVCEIGSK+ + GE+I VK+LGILA+IDEGETDWK+IAIN +D
Sbjct: 104 PGHNDKHTGCCGDNDPIDVCEIGSKVCARGEIIGVKVLGILAMIDEGETDWKVIAINVDD 163
Query: 212 PEASKFHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKST 271
P+A+ ++DI+DVK+ KPGYLEAT++WFR YKVPDGKPEN+FAFN EFK+K FA+++IKST
Sbjct: 164 PDAANYNDINDVKRLKPGYLEATVDWFRRYKVPDGKPENEFAFNAEFKDKDFAIDIIKST 223
Query: 272 HQCWKALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESV 314
H WKAL+ KK NG I+C N +S+SPF+C + AR++V+++
Sbjct: 224 HDHWKALVTKKTNGKGISCMNTTLSESPFKCDPDAARAIVDAL 266
>gi|77812680 inorganic pyrophosphatase 2 isoform 3 precursor [Homo
sapiens]
Length = 232
Score = 330 bits (845), Expect = 1e-90
Identities = 158/159 (99%), Positives = 159/159 (100%)
Query: 176 KILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 235
+ILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL
Sbjct: 74 EILSCGEVIHVKILGILALIDEGETDWKLIAINANDPEASKFHDIDDVKKFKPGYLEATL 133
Query: 236 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 295
NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI
Sbjct: 134 NWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWKALLMKKCNGGAINCTNVQI 193
Query: 296 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 194 SDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 232
Score = 153 bits (387), Expect = 2e-37
Identities = 74/74 (100%), Positives = 74/74 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFFKNVTGHYI 60
Query: 61 SPFHDIPLKVNSKE 74
SPFHDIPLKVNSKE
Sbjct: 61 SPFHDIPLKVNSKE 74
>gi|77812682 inorganic pyrophosphatase 2 isoform 4 precursor [Homo
sapiens]
Length = 168
Score = 246 bits (627), Expect = 3e-65
Identities = 116/118 (98%), Positives = 117/118 (99%)
Query: 217 FHDIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 276
F +IDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK
Sbjct: 51 FFNIDDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQCWK 110
Query: 277 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 334
ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK
Sbjct: 111 ALLMKKCNGGAINCTNVQISDSPFRCTQEEARSLVESVSSSPNKESNEEEQVWHFLGK 168
Score = 107 bits (267), Expect = 1e-23
Identities = 52/52 (100%), Positives = 52/52 (100%)
Query: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52
MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF
Sbjct: 1 MSALLRLLRTGAPAAACLRLGTSAGTGSRRAMALYHTEERGQPCSQNYRLFF 52
>gi|57165424 cullin 4A isoform 1 [Homo sapiens]
Length = 759
Score = 30.4 bits (67), Expect = 2.3
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 204 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 254
L+ + N+ + F +I + L TL L K P GK ++F F
Sbjct: 597 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 656
Query: 255 NGEFKNKAFALEV 267
NGEFK+K F +++
Sbjct: 657 NGEFKHKLFRIKI 669
>gi|11140811 cullin 4A isoform 2 [Homo sapiens]
Length = 659
Score = 30.4 bits (67), Expect = 2.3
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 9/73 (12%)
Query: 204 LIAINANDPEASKFHDIDDVKKFKPGYLEATLNWFR------LYKVPDGKPE---NQFAF 254
L+ + N+ + F +I + L TL L K P GK ++F F
Sbjct: 497 LVLLMFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIF 556
Query: 255 NGEFKNKAFALEV 267
NGEFK+K F +++
Sbjct: 557 NGEFKHKLFRIKI 569
>gi|221316749 carboxypeptidase A3 precursor [Homo sapiens]
Length = 417
Score = 29.6 bits (65), Expect = 3.9
Identities = 14/49 (28%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 115 NPIKQYVKDGKLRYVANIFPYKGYIWNYGTLPQTWEDPHEKDKSTNCFG 163
N I + D Y+ +F GYIW++ T + W K++++ C G
Sbjct: 200 NKIMTKLLDRMNFYILPVFNVDGYIWSW-TKNRMWRKNRSKNQNSKCIG 247
>gi|88501736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform a
[Homo sapiens]
Length = 277
Score = 29.3 bits (64), Expect = 5.2
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 221 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 273
DD+KK Y L W PD P+N+ +FK A A EV+ H+
Sbjct: 17 DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61
>gi|27151736 DnaJ (Hsp40) homolog, subfamily B, member 2 isoform b
[Homo sapiens]
Length = 324
Score = 29.3 bits (64), Expect = 5.2
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 8/53 (15%)
Query: 221 DDVKKFKPGYLEATLNWFRLYKVPDGKPENQFAFNGEFKNKAFALEVIKSTHQ 273
DD+KK Y L W PD P+N+ +FK A A EV+ H+
Sbjct: 17 DDIKK---AYRRKALQWH-----PDKNPDNKEFAEKKFKEVAEAYEVLSDKHK 61
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 28.5 bits (62), Expect = 8.8
Identities = 13/36 (36%), Positives = 19/36 (52%)
Query: 81 KKARNDEYENLFNMIVEIPRWTNAKMEIATKEPMNP 116
K RND + N + + E + TN EI +K+P P
Sbjct: 2383 KMVRNDMFYNHYPYVPETEQETNVASEIPSKQPETP 2418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,496,959
Number of Sequences: 37866
Number of extensions: 633370
Number of successful extensions: 1427
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1415
Number of HSP's gapped (non-prelim): 15
length of query: 334
length of database: 18,247,518
effective HSP length: 103
effective length of query: 231
effective length of database: 14,347,320
effective search space: 3314230920
effective search space used: 3314230920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.