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Search of human proteins with 27777657
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo sapiens]
(414 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27777657 serine (or cysteine) proteinase inhibitor, clade A (... 825 0.0
gi|189163542 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163540 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163538 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163536 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163534 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163532 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163530 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|189163528 serine proteinase inhibitor, clade A, member 1 [Hom... 306 3e-83
gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo... 306 3e-83
gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo... 306 3e-83
gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo... 306 3e-83
gi|194018472 serine (or cysteine) proteinase inhibitor, clade A ... 278 6e-75
gi|110225347 serine (or cysteine) proteinase inhibitor, clade A ... 272 5e-73
gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,... 270 1e-72
gi|50659080 serpin peptidase inhibitor, clade A, member 3 precur... 270 2e-72
gi|122937297 serpin peptidase inhibitor, clade A (alpha-1 antipr... 269 3e-72
gi|73858564 corticosteroid binding globulin precursor [Homo sapi... 261 8e-70
gi|21361302 serine (or cysteine) proteinase inhibitor, clade A (... 241 9e-64
gi|154759291 serine (or cysteine) proteinase inhibitor, clade A ... 216 4e-56
gi|7705879 serine (or cysteine) proteinase inhibitor, clade A (a... 216 4e-56
gi|28076869 serine (or cysteine) proteinase inhibitor, clade B (... 181 8e-46
gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Hom... 181 1e-45
gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo s... 178 7e-45
gi|5902072 serine (or cysteine) proteinase inhibitor, clade B (o... 178 7e-45
gi|41152086 serine (or cysteine) proteinase inhibitor, clade B (... 176 3e-44
gi|38504669 serine (or cysteine) proteinase inhibitor, clade B (... 176 3e-44
gi|38504673 serine (or cysteine) proteinase inhibitor, clade B (... 176 3e-44
gi|73858566 heparin cofactor II precursor [Homo sapiens] 172 5e-43
gi|4826902 serine (or cysteine) proteinase inhibitor, clade B (o... 171 1e-42
>gi|27777657 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 12 [Homo
sapiens]
Length = 414
Score = 825 bits (2130), Expect = 0.0
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLL 60
MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLL
Sbjct: 1 MNPTLGLAIFLAVLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLL 60
Query: 61 KKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYII 120
KKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYII
Sbjct: 61 KKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEKDLHEGFHYII 120
Query: 121 HELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDF 180
HELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDF
Sbjct: 121 HELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDF 180
Query: 181 ISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPM 240
ISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPM
Sbjct: 181 ISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPM 240
Query: 241 MFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLS 300
MFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLS
Sbjct: 241 MFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLS 300
Query: 301 RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKM 360
RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKM
Sbjct: 301 RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKM 360
Query: 361 DERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK 414
DERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK
Sbjct: 361 DERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK 414
>gi|189163542 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163540 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163538 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163536 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163534 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163532 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163530 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|189163528 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|50363219 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|50363221 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|50363217 serine proteinase inhibitor, clade A, member 1 [Homo
sapiens]
Length = 418
Score = 306 bits (783), Expect = 3e-83
Identities = 155/363 (42%), Positives = 228/363 (62%), Gaps = 2/363 (0%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR--KMPEKD 111
+ F L ++LA + NIF SP+SI+TAF+ML LG + T DEI +G NF ++PE
Sbjct: 56 EFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQ 115
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+HEGF ++ L Q L+L+ GN LF+ + L+ KFLED K Y +E NF + E
Sbjct: 116 IHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTE 175
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLE 231
A+KQIND++ + T GKI +L++ +D TV L NYIFF+ +W+ F+ T+EEDF ++
Sbjct: 176 EAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVD 235
Query: 232 KNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDT 291
+ ++VKVPMM R G++ + + KLS +L + Y N TAIF LPDEGKL+HLE L D
Sbjct: 236 QVTTVKVPMMKRLGMFNIQHCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDI 295
Query: 292 FSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGE 351
+++ RR + +P+L +TGT+DLK L +G++K+F DL+ + LK+ +
Sbjct: 296 ITKFLENEDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLSK 355
Query: 352 AVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
AVHKA L +DE+GTE A + +PM P VK +KP++ L+ + S LF+GK+VNP
Sbjct: 356 AVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
Query: 412 IGK 414
K
Sbjct: 416 TQK 418
>gi|194018472 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 5 [Homo
sapiens]
Length = 406
Score = 278 bits (711), Expect = 6e-75
Identities = 151/405 (37%), Positives = 237/405 (58%), Gaps = 14/405 (3%)
Query: 13 VLLTVKGLLKPSFSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNI 72
VLL+ +G PR K E + A D F L + LA P ++I
Sbjct: 10 VLLSPQGASLHRHHPREMKKRVE----DLHVGATVAPSSRRDFTFDLYRALASAAPSQSI 65
Query: 73 FLSPLSISTAFSMLCLGAQDSTLDEIKQGF--NFRKMPEKDLHEGFHYIIHELTQKTQDL 130
F SP+SIS + +ML LGA ST +I +G N +K EK+LH GF ++ EL Q
Sbjct: 66 FFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKELHRGFQQLLQELNQPRDGF 125
Query: 131 KLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKIN 190
+LS+GN LF D + Q F+ K Y A+T TNF++ A KQIND+++++T GKI
Sbjct: 126 QLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIV 185
Query: 191 NLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVG 250
+L++N+D V+++ NYIFF+A+W+ F+ T+E+DF++ + V+VPMM R Y
Sbjct: 186 DLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHYL 245
Query: 251 YDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPR 310
D LSC ++ +PYQ N TA+FILP EGK++ +E GL T +W + +R +++ +P+
Sbjct: 246 LDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMFKKRQLELYLPK 305
Query: 311 LHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAG 370
+ G++ L+K L +G+S +F H DL+ I+ H +++V E VHKA +++DE GT AA
Sbjct: 306 FSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQVSEMVHKAVVEVDESGTRAAAA 365
Query: 371 TGA----QTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
TG ++ + + +V ++P+L+ I ++LFLGK+ P
Sbjct: 366 TGTIFTFRSARLNSQRLV-FNRPFLMFIVDN---NILFLGKVNRP 406
>gi|110225347 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 9 isoform
A [Homo sapiens]
Length = 435
Score = 272 bits (695), Expect = 5e-73
Identities = 142/414 (34%), Positives = 238/414 (57%), Gaps = 9/414 (2%)
Query: 7 LAIFLAVLLTVKGLLKPSF--SPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLA 64
+A +L +L GL P + SP N + + A ++ N D F+L ++L
Sbjct: 19 MASYLYGVLFAVGLCAPIYCVSPANAPSAYPRPSSTKSTPASQVYSLNTDFAFRLYRRLV 78
Query: 65 FYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRKMPEKDLHEGFHYIIHE 122
P +NIF SP+S+ST+ +ML LGA T +I QG FN PE +H+GF +++H
Sbjct: 79 LETPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTHTPESAIHQGFQHLVHS 138
Query: 123 LTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFIS 182
LT ++DL L +G+ LF+ + LQ Q FL + K Y AE T+F N +AQ +IN +
Sbjct: 139 LTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVK 198
Query: 183 QKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEE-DFFLEKNSSVKVPMM 241
+KT GK+ ++I+ +D T M+L N+IFF+A+W+ F P T++ F + + +V VPMM
Sbjct: 199 KKTQGKVVDIIQGLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMM 258
Query: 242 FRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVDTFSRWKTLLSR 301
+ + G D +L+C +L++ Y+ + A F+LP +GK++ LE+ L T +W L +
Sbjct: 259 HQKEQFAFGVDTELNCFVLQMDYKGDAVAFFVLPSKGKMRQLEQALSARTLRKWSHSLQK 318
Query: 302 RVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMD 361
R ++V +PR ++ +++L+ L +G+ +F+++ D + IA SL+V +A HKA L +
Sbjct: 319 RWIEVFIPRFSISASYNLETILPKMGIQNVFDKNADFSGIAKRDSLQVSKATHKAVLDVS 378
Query: 362 ERGTEGAAGTGAQTLPME----TPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
E GTE A T + + + V ++ +L++I ++ +LFLGK+ NP
Sbjct: 379 EEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENP 432
>gi|205277441 serine (or cysteine) proteinase inhibitor, clade A,
member 7 [Homo sapiens]
Length = 415
Score = 270 bits (691), Expect = 1e-72
Identities = 141/367 (38%), Positives = 217/367 (59%), Gaps = 7/367 (1%)
Query: 52 NMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQ--GFNFRKMPE 109
N D F L ++ P +NIF SP+SIS A ML GA ST EI + GFN P
Sbjct: 46 NADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNLTDTPM 105
Query: 110 KDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQN 169
++ GF ++I L ++L+L IGN LFI + L+P KFL D K Y E T+F N
Sbjct: 106 VEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFSTDFSN 165
Query: 170 LEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE-EDF 228
+ A+++IN + +T GK+ LI+++ P T+M+L NYI F+A+W + FDP+ T++ F
Sbjct: 166 ISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTEDSSSF 225
Query: 229 FLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQ 288
++K ++V+VPMM + Y D +L+CT+L++ Y KN A+F+LP EG+++ +E +
Sbjct: 226 LIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMESVEAAMS 285
Query: 289 VDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLK 348
T +W LL + VD+ VP+ ++ T+DL TL +G+ + E+ D + + LK
Sbjct: 286 SKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLK 345
Query: 349 VGEAVHKAELKMDERGTEGAAGTGAQ--TLPMETPL--VVKIDKPYLLLIYSEKIPSVLF 404
+ A HKA L + E+GTE AA + P T L +++ID+ ++LLI S+LF
Sbjct: 346 LSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILF 405
Query: 405 LGKIVNP 411
LGK+VNP
Sbjct: 406 LGKVVNP 412
>gi|50659080 serpin peptidase inhibitor, clade A, member 3 precursor
[Homo sapiens]
Length = 423
Score = 270 bits (690), Expect = 2e-72
Identities = 140/373 (37%), Positives = 227/373 (60%), Gaps = 10/373 (2%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFR 105
LA N+D F L K+L P +N+ SPLSISTA + L LGA ++TL EI +G FN
Sbjct: 49 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 108
Query: 106 KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILT 165
+ E ++H+ F +++ L Q + +L+LS+GN +F+ ++L +F EDAK Y +E T
Sbjct: 109 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 168
Query: 166 NFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE 225
+FQ+ A+K IND++ T GKI +LI+++D T+M+L NYIFF+A+W+ FDP T +
Sbjct: 169 DFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQ 228
Query: 226 EDFFLEKNSSVKVPMMFRSGIYQVGY--DDKLSCTILEIPYQKNITAIFILPDEGKLKHL 283
F+L K V VPMM + + Y D++LSCT++E+ Y N +A+FILPD+ K++ +
Sbjct: 229 SRFYLSKKKWVMVPMMSLHHL-TIPYFRDEELSCTVVELKYTGNASALFILPDQDKMEEV 287
Query: 284 EKGLQVDTFSRWKTLLS-RRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIA 342
E L +T RW+ L R + ++ +P+ ++ ++L L +G+ + F DL+ I
Sbjct: 288 EAMLLPETLKRWRDSLEFREIGELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSGIT 347
Query: 343 PHRSLKVGEAVHKAELKMDERGTEGAAGTGAQ----TLPMETPLVVKIDKPYLLLIYSEK 398
R+L V + VHKA L + E GTE +A T + + +ET +V+ ++P+L++I
Sbjct: 348 GARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTD 407
Query: 399 IPSVLFLGKIVNP 411
++ F+ K+ NP
Sbjct: 408 TQNIFFMSKVTNP 420
>gi|122937297 serpin peptidase inhibitor, clade A (alpha-1
antiproteinase, antitrypsin), member 11 [Homo sapiens]
Length = 422
Score = 269 bits (688), Expect = 3e-72
Identities = 139/367 (37%), Positives = 225/367 (61%), Gaps = 10/367 (2%)
Query: 54 DLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRKMPEKD 111
+ +L K+LA PG NIF SP+SIST ++L LGAQ +T I +G FN + PE D
Sbjct: 56 NFALRLYKELAADAPG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTETPEAD 114
Query: 112 LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLE 171
+H+GF ++H L + L+L +GN+LF+D+RL+P++ +L+ K Y A NF +
Sbjct: 115 IHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSV 174
Query: 172 MAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVT-KEEDFFL 230
+QIND++ ++T+G++ + + T M+LANYIFF+A+WKH F T K+E FF+
Sbjct: 175 TTGRQINDYLRRQTYGQVVDCLPEFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFV 234
Query: 231 EKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEKGLQVD 290
++ +S++VPMM + +++ YD L+CT+L+I Y+ N A+ +LPD GK+K +E LQ
Sbjct: 235 DERTSLQVPMMHQKEMHRFLYDQDLACTVLQIEYRGNALALLVLPDPGKMKQVEAALQPQ 294
Query: 291 TFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVG 350
T +W LL ++D+ +PR ++GT++L+ L IG++ I D + + + +
Sbjct: 295 TLRKWGQLLLPSLLDLHLPRFSISGTYNLEDILPQIGLTNILNLEADFSGVTGQLNKTIS 354
Query: 351 EAVHKAELKMDERGTEGAAGTGAQTLP-----METPLVVKIDKPYLLLIYSEKIPSVLFL 405
+ HKA + M E+GTE A +G + P M P ++P+LLL++ S+LFL
Sbjct: 355 KVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDP-HAHFNRPFLLLLWEVTTQSLLFL 413
Query: 406 GKIVNPI 412
GK+VNP+
Sbjct: 414 GKVVNPV 420
>gi|73858564 corticosteroid binding globulin precursor [Homo
sapiens]
Length = 405
Score = 261 bits (667), Expect = 8e-70
Identities = 127/367 (34%), Positives = 215/367 (58%), Gaps = 2/367 (0%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFR 105
LA N+D F L K L +P +NIF+SP+SIS A +ML LG T ++ QG FN
Sbjct: 39 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 98
Query: 106 KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILT 165
+ E ++H+GF ++ + L++++GN LF+D L+ F D K++Y +E +
Sbjct: 99 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 158
Query: 166 NFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKE 225
NFQ+ A +QIN ++ KT GKI +L +D +++L NYIFF+ W FD T+E
Sbjct: 159 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 218
Query: 226 EDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNITAIFILPDEGKLKHLEK 285
E+F++++ + VKVPMM +S +D +L C ++++ Y N T FILPD+GK+ +
Sbjct: 219 ENFYVDETTVVKVPMMLQSSTISYLHDAELPCQLVQMNYVGNGTVFFILPDKGKMNTVIA 278
Query: 286 GLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHR 345
L DT +RW L+ VD+ +P++ ++G +DL L +G++ +F + ++I
Sbjct: 279 ALSRDTINRWSAGLTSSQVDLYIPKVTISGVYDLGDVLEEMGIADLFTNQANFSRITQDA 338
Query: 346 SLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFL 405
LK + VHKA L+++E G + A TG P++++ ++P++++I+ S LFL
Sbjct: 339 QLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKPIILRFNQPFIIMIFDHFTWSSLFL 398
Query: 406 GKIVNPI 412
+++NP+
Sbjct: 399 ARVMNPV 405
>gi|21361302 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 4 [Homo
sapiens]
Length = 427
Score = 241 bits (615), Expect = 9e-64
Identities = 130/379 (34%), Positives = 221/379 (58%), Gaps = 18/379 (4%)
Query: 47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNF 104
++A N D F+ +A PG+NIF SPLSIS A++ML LGA + +I +G FN
Sbjct: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109
Query: 105 RKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETIL 164
++ E D+H GF +++H L L+ +G+ LF+ L+ KFL D Y A+
Sbjct: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169
Query: 165 TNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTK 224
TNF + + IND + ++T GKI +L+ + +M+L NYI+F+A W+ F + T
Sbjct: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229
Query: 225 EEDFFLEKNSSVKVPMMFRSGIYQVGYDDK-LSCTILEIPYQKNITAIFILPDEGKLKHL 283
+DF++++N++V+VPMM + + D+ L C++L + Y+ + T FILP++GK++ +
Sbjct: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289
Query: 284 EKGLQVDTFSRWKTLLSRR----VVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLT 339
E+ L + RW LL +R +++ +P+ ++G++ L + L +G + +F + DL+
Sbjct: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349
Query: 340 KIAPHRSLKVGEAVHKAELKMDERGTEGAAGT-------GAQTLPMETPLVVKIDKPYLL 392
I + L+ ++ HKA L +DE GTE AA T AQT +++ ++P+L+
Sbjct: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT----NRHILRFNRPFLV 405
Query: 393 LIYSEKIPSVLFLGKIVNP 411
+I+S SVLFLGK+V+P
Sbjct: 406 VIFSTSTQSVLFLGKVVDP 424
>gi|154759291 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 216 bits (549), Expect = 4e-56
Identities = 119/385 (30%), Positives = 212/385 (55%), Gaps = 6/385 (1%)
Query: 31 KALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGA 90
KA E + W + ++LA++ + GF LL+K++ + G +F SP +S A + L LGA
Sbjct: 59 KASEEEKAWLMA-SRQQLAKETSNFGFSLLRKISMRHDGNMVF-SPFGMSLAMTGLMLGA 116
Query: 91 QDSTLDEIKQGFNFR--KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQR 148
T +IK+G + + K + L + E + +L L+ G+ FI + +
Sbjct: 117 TGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKE 176
Query: 149 KFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYI 208
F +K ++ E + NF+N A++ +N +I+++T GKI L + I+P T ++L +YI
Sbjct: 177 TFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYI 236
Query: 209 FFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNI 268
F+ +W FDP T+ + F L+K ++KVPMM+ +G + +D C +L++PYQ N
Sbjct: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296
Query: 269 TAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIG 327
T + +L ++ G LE L D W + R ++V P+ + +++ + L +G
Sbjct: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMG 356
Query: 328 VSKIFEEHGDLTKI-APHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKI 386
+ +IF DL+++ A R+L+V + + +++DERGTE AG ++ P V+K+
Sbjct: 357 IRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV 416
Query: 387 DKPYLLLIYSEKIPSVLFLGKIVNP 411
D+P+ +IY E +LFLG++VNP
Sbjct: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441
>gi|7705879 serine (or cysteine) proteinase inhibitor, clade A
(alpha-1 antiproteinase, antitrypsin), member 10 [Homo
sapiens]
Length = 444
Score = 216 bits (549), Expect = 4e-56
Identities = 119/385 (30%), Positives = 212/385 (55%), Gaps = 6/385 (1%)
Query: 31 KALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGA 90
KA E + W + ++LA++ + GF LL+K++ + G +F SP +S A + L LGA
Sbjct: 59 KASEEEKAWLMA-SRQQLAKETSNFGFSLLRKISMRHDGNMVF-SPFGMSLAMTGLMLGA 116
Query: 91 QDSTLDEIKQGFNFR--KMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQR 148
T +IK+G + + K + L + E + +L L+ G+ FI + +
Sbjct: 117 TGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKE 176
Query: 149 KFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYI 208
F +K ++ E + NF+N A++ +N +I+++T GKI L + I+P T ++L +YI
Sbjct: 177 TFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYI 236
Query: 209 FFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNI 268
F+ +W FDP T+ + F L+K ++KVPMM+ +G + +D C +L++PYQ N
Sbjct: 237 LFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNA 296
Query: 269 TAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIG 327
T + +L ++ G LE L D W + R ++V P+ + +++ + L +G
Sbjct: 297 TMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMG 356
Query: 328 VSKIFEEHGDLTKI-APHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKI 386
+ +IF DL+++ A R+L+V + + +++DERGTE AG ++ P V+K+
Sbjct: 357 IRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKV 416
Query: 387 DKPYLLLIYSEKIPSVLFLGKIVNP 411
D+P+ +IY E +LFLG++VNP
Sbjct: 417 DRPFHFMIYEETSGMLLFLGRVVNP 441
>gi|28076869 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 4 [Homo sapiens]
Length = 390
Score = 181 bits (460), Expect = 8e-46
Identities = 114/365 (31%), Positives = 194/365 (53%), Gaps = 24/365 (6%)
Query: 71 NIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEK--------------DLHEGF 116
NIF SP+SI++A M+ LGA+D+T +I + +F ++ E ++H F
Sbjct: 26 NIFYSPISITSALGMVLLGAKDNTAQQISKVLHFDQVTENTTEKAATYHVDRSGNVHHQF 85
Query: 117 HYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNL-EMAQK 175
++ E + T +L I N LF ++ Q +++L+ K FY T+F N E ++K
Sbjct: 86 QKLLTEFNKSTDAYELKIANKLFGEKTYQFLQEYLDAIKKFYQTSVESTDFANAPEESRK 145
Query: 176 QINDFISQKTHGKINNLIEN--IDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKN 233
+IN ++ +T+ KI NL + I T ++L N I+F+ +W+++F TKEE F+ KN
Sbjct: 146 KINSWVESQTNEKIKNLFPDGTIGNDTTLVLVNAIYFKGQWENKFKKENTKEEKFWPNKN 205
Query: 234 SSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQ-KNITAIFILPDE-GKLKHLEKGLQVDT 291
+ V MM + + + + +LEIPY+ K+++ I +LP+E L+ LE+ L +
Sbjct: 206 TYKSVQMMRQYNSFNFALLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEK 265
Query: 292 FSRWKTLLSRR--VVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKV 349
W +L + R VD+ +PR M ++DLK TL +G+ IF DL+ + L V
Sbjct: 266 LMEWTSLQNMRETCVDLHLPRFKMEESYDLKDTLRTMGMVNIFNGDADLSGMTWSHGLSV 325
Query: 350 GEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVK---IDKPYLLLIYSEKIPSVLFLG 406
+ +HKA +++ E G E AA T + + +P + + P+L I K S+LF G
Sbjct: 326 SKVLHKAFVEVTEEGVEAAAATAVVVVELSSPSTNEEFCCNHPFLFFIRQNKTNSILFYG 385
Query: 407 KIVNP 411
+ +P
Sbjct: 386 RFSSP 390
>gi|156071456 serpin peptidase inhibitor, clade B, member 11 [Homo
sapiens]
Length = 392
Score = 181 bits (459), Expect = 1e-45
Identities = 118/391 (30%), Positives = 204/391 (52%), Gaps = 29/391 (7%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKM 107
L+ N++ + K+L N G NIF S LS+ A SM+ LGA+ T +++++ +F
Sbjct: 4 LSTANVEFCLDVFKELNSNNIGDNIFFSSLSLLYALSMVLLGARGETEEQLEKVLHFSHT 63
Query: 108 PE------KD---------LHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLE 152
+ KD +H F ++ Q + LSI N L+ + + +++L
Sbjct: 64 VDSLKPGFKDSPKCSQAGRIHSEFGVEFSQINQPDSNCTLSIANRLYGTKTMAFHQQYLS 123
Query: 153 DAKNFYSAETILTNF-QNLEMAQKQINDFISQKTHGKINNLI--ENIDPGTVMLLANYIF 209
++ +Y A +F Q+ E +K IN ++ KT+GK+ NL IDP +VM+L N I+
Sbjct: 124 CSEKWYQARLQTVDFEQSTEETRKTINAWVENKTNGKVANLFGKSTIDPSSVMVLVNAIY 183
Query: 210 FRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQKNIT 269
F+ +W+++F T + F L + +V V MM++ G +++ + + +LE+PY N
Sbjct: 184 FKGQWQNKFQVRETVKSPFQLSEGKNVTVEMMYQIGTFKLAFVKEPQMQVLELPYVNNKL 243
Query: 270 AIFILPDEG--KLKHLEKGLQVDTFSRW--KTLLSRRVVDVSVPRLHMTGTFDLKKTLSY 325
++ IL G LK +EK L TF W + + R V+V +PR + ++L L
Sbjct: 244 SMIILLPVGIANLKQIEKQLNSGTFHEWTSSSNMMEREVEVHLPRFKLETKYELNSLLKS 303
Query: 326 IGVSKIFEE-HGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTG----AQTLPMET 380
+GV+ +F + DL+ ++P + L + +A+HK+ L + E GTE AA TG ++LPM
Sbjct: 304 LGVTDLFNQVKADLSGMSPTKGLYLSKAIHKSYLDVSEEGTEAAAATGDSIAVKSLPMRA 363
Query: 381 PLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
K + P+L I ++LF GK+ +P
Sbjct: 364 QF--KANHPFLFFIRHTHTNTILFCGKLASP 392
>gi|4758906 serpin peptidase inhibitor, clade B, member 9 [Homo
sapiens]
Length = 376
Score = 178 bits (452), Expect = 7e-45
Identities = 110/375 (29%), Positives = 199/375 (53%), Gaps = 13/375 (3%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKM 107
L+ + +LLK L NP N+F SP+SIS+A +M+ LGA+ +T ++ Q +
Sbjct: 4 LSNASGTFAIRLLKILCQDNPSHNVFCSPVSISSALAMVLLGAKGNTATQMAQALSLNT- 62
Query: 108 PEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNF 167
E+D+H F ++ E+ + L N LF ++ Q F E FY AE +F
Sbjct: 63 -EEDIHRAFQSLLTEVNKAGTQYLLRTANRLFGEKTCQFLSTFKESCLQFYHAELKELSF 121
Query: 168 -QNLEMAQKQINDFISQKTHGKINNLI--ENIDPGTVMLLANYIFFRARWKHEFDPNVTK 224
+ E ++K IN ++S+KT GKI L+ +ID T ++L N I+F+ +W FD T+
Sbjct: 122 IRAAEESRKHINTWVSKKTEGKIEELLPGSSIDAETRLVLVNAIYFKGKWNEPFDETYTR 181
Query: 225 EEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY-QKNITAIFILPDEG-KLKH 282
E F + + V MM++ +++ + ++ +LE+PY +K ++ + +LPD+G +L
Sbjct: 182 EMPFKINQEEQRPVQMMYQEATFKLAHVGEVRAQLLELPYARKELSLLVLLPDDGVELST 241
Query: 283 LEKGLQVDTFSRW--KTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEE-HGDLT 339
+EK L + + W + V+V +P+ + +D++ L ++G+ F++ DL+
Sbjct: 242 VEKSLTFEKLTAWTKPDCMKSTEVEVLLPKFKLQEDYDMESVLRHLGIVDAFQQGKADLS 301
Query: 340 KIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLP---METPLVVKIDKPYLLLIYS 396
++ R L + + VHK+ ++++E GTE AA + + ME+ D P+L I
Sbjct: 302 AMSAERDLCLSKFVHKSFVEVNEEGTEAAAASSCFVVAECCMESGPRFCADHPFLFFIRH 361
Query: 397 EKIPSVLFLGKIVNP 411
+ S+LF G+ +P
Sbjct: 362 NRANSILFCGRFSSP 376
>gi|5902072 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 3 [Homo sapiens]
Length = 390
Score = 178 bits (452), Expect = 7e-45
Identities = 115/365 (31%), Positives = 193/365 (52%), Gaps = 24/365 (6%)
Query: 71 NIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKMPEK--------------DLHEGF 116
NIF SP+SI++A M+ LGA+D+T +IK+ +F ++ E ++H F
Sbjct: 26 NIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQF 85
Query: 117 HYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNL-EMAQK 175
++ E + T +L I N LF ++ +++L+ K FY +F N E ++K
Sbjct: 86 QKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRK 145
Query: 176 QINDFISQKTHGKINNLIE--NIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKN 233
+IN ++ +T+ KI NLI NI T ++L N I+F+ +W+ +F+ TKEE F+ KN
Sbjct: 146 KINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKN 205
Query: 234 SSVKVPMMFRSGIYQVGYDDKLSCTILEIPYQ-KNITAIFILPDE-GKLKHLEKGLQVDT 291
+ + MM + + + + +LEIPY+ K+++ I +LP+E L+ LE+ L +
Sbjct: 206 TYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEK 265
Query: 292 FSRWKTLLSRRV--VDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKV 349
W +L + R VD+ +PR + ++DLK TL +G+ IF DL+ + R L +
Sbjct: 266 LMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVL 325
Query: 350 GEAVHKAELKMDERGTEGAAGT---GAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLG 406
+HKA +++ E G E AA T G + P T + P+L I K S+LF G
Sbjct: 326 SGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYG 385
Query: 407 KIVNP 411
+ +P
Sbjct: 386 RFSSP 390
>gi|41152086 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 6 [Homo sapiens]
Length = 376
Score = 176 bits (447), Expect = 3e-44
Identities = 117/375 (31%), Positives = 197/375 (52%), Gaps = 13/375 (3%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRKM 107
LA N LLK L N +N+F SP+S+S A +M+ +GA+ +T ++ Q +F K
Sbjct: 4 LAEANGTFALNLLKTLGKDN-SKNVFFSPMSMSCALAMVYMGAKGNTAAQMAQILSFNKS 62
Query: 108 PEK-DLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTN 166
D+H+GF ++ E+ + L + N LF ++ F + + FY AE +
Sbjct: 63 GGGGDIHQGFQSLLTEVNKTGTQYLLRMANRLFGEKSCDFLSSFRDSCQKFYQAEMEELD 122
Query: 167 FQN-LEMAQKQINDFISQKTHGKINNLIE--NIDPGTVMLLANYIFFRARWKHEFDPNVT 223
F + +E ++K IN ++++KT GKI L+ ++DP T ++L N ++FR W +FD T
Sbjct: 123 FISAVEKSRKHINTWVAEKTEGKIAELLSPGSVDPLTRLVLVNAVYFRGNWDEQFDKENT 182
Query: 224 KEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY-QKNITAIFILPDE-GKLK 281
+E F + KN V MMF+ ++ Y ++ IL +PY K + I +LPDE L+
Sbjct: 183 EERLFKVSKNEEKPVQMMFKQSTFKKTYIGEIFTQILVLPYVGKELNMIIMLPDETTDLR 242
Query: 282 HLEKGLQVDTFSRWKTL--LSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFE-EHGDL 338
+EK L + F W L + V+VS+PR + ++D++ L +G++ FE D
Sbjct: 243 TVEKELTYEKFVEWTRLDMMDEEEVEVSLPRFKLEESYDMESVLRNLGMTDAFELGKADF 302
Query: 339 TKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPLVVKI--DKPYLLLIYS 396
+ ++ L + + VHK+ ++++E GTE AA T A + V + D P+L I
Sbjct: 303 SGMS-QTDLSLSKVVHKSFVEVNEEGTEAAAATAAIMMMRCARFVPRFCADHPFLFFIQH 361
Query: 397 EKIPSVLFLGKIVNP 411
K +LF G+ +P
Sbjct: 362 SKTNGILFCGRFSSP 376
>gi|38504669 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 176 bits (446), Expect = 3e-44
Identities = 112/377 (29%), Positives = 197/377 (52%), Gaps = 17/377 (4%)
Query: 47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRK 106
+L N L K L + RN+F SP+SIS+A +M+ +GA+ ST ++ Q K
Sbjct: 3 DLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYK 62
Query: 107 MPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTN 166
+ D+H GF ++ E+ + L N LF ++ F E + FY AE +
Sbjct: 63 --DGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 167 F-QNLEMAQKQINDFISQKTHGKINNLIE--NIDPGTVMLLANYIFFRARWKHEFDPNVT 223
F ++ E +K IND++++KT GKI+ +++ +DP T ++L N I+F+ +W +FD T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 224 KEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY-QKNITAIFILPDEG-KLK 281
+ F V MMF+ +++GY D++ +LE+PY ++ ++ + +LPD+ L
Sbjct: 181 RGM-LFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239
Query: 282 HLEKGLQVDTFSRW--KTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEE-HGDL 338
+EK L + F W L++ V V +PRL + ++DL+ L +G+ F+E D
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299
Query: 339 TKIAPHRSLKVGEAVHKAELKMDERGTEGAAGT----GAQTLPMETPLVVKIDKPYLLLI 394
+ ++ +++ + + HK ++++E GTE AA T ++ ME D P+L I
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA--DHPFLFFI 357
Query: 395 YSEKIPSVLFLGKIVNP 411
K +LF G+ +P
Sbjct: 358 RHHKTNCILFCGRFSSP 374
>gi|38504673 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 8 isoform a [Homo sapiens]
Length = 374
Score = 176 bits (446), Expect = 3e-44
Identities = 112/377 (29%), Positives = 197/377 (52%), Gaps = 17/377 (4%)
Query: 47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFRK 106
+L N L K L + RN+F SP+SIS+A +M+ +GA+ ST ++ Q K
Sbjct: 3 DLCEANGTFAISLFKILGEEDNSRNVFFSPMSISSALAMVFMGAKGSTAAQMSQALCLYK 62
Query: 107 MPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTN 166
+ D+H GF ++ E+ + L N LF ++ F E + FY AE +
Sbjct: 63 --DGDIHRGFQSLLSEVNRTGTQYLLRTANRLFGEKTCDFLPDFKEYCQKFYQAELEELS 120
Query: 167 F-QNLEMAQKQINDFISQKTHGKINNLIE--NIDPGTVMLLANYIFFRARWKHEFDPNVT 223
F ++ E +K IND++++KT GKI+ +++ +DP T ++L N I+F+ +W +FD T
Sbjct: 121 FAEDTEECRKHINDWVAEKTEGKISEVLDAGTVDPLTKLVLVNAIYFKGKWNEQFDRKYT 180
Query: 224 KEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY-QKNITAIFILPDEG-KLK 281
+ F V MMF+ +++GY D++ +LE+PY ++ ++ + +LPD+ L
Sbjct: 181 RGM-LFKTNEEKKTVQMMFKEAKFKMGYADEVHTQVLELPYVEEELSMVILLPDDNTDLA 239
Query: 282 HLEKGLQVDTFSRW--KTLLSRRVVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEE-HGDL 338
+EK L + F W L++ V V +PRL + ++DL+ L +G+ F+E D
Sbjct: 240 VVEKALTYEKFKAWTNSEKLTKSKVQVFLPRLKLEESYDLEPFLRRLGMIDAFDEAKADF 299
Query: 339 TKIAPHRSLKVGEAVHKAELKMDERGTEGAAGT----GAQTLPMETPLVVKIDKPYLLLI 394
+ ++ +++ + + HK ++++E GTE AA T ++ ME D P+L I
Sbjct: 300 SGMSTEKNVPLSKVAHKCFVEVNEEGTEAAAATAVVRNSRCSRMEPRFCA--DHPFLFFI 357
Query: 395 YSEKIPSVLFLGKIVNP 411
K +LF G+ +P
Sbjct: 358 RHHKTNCILFCGRFSSP 374
>gi|73858566 heparin cofactor II precursor [Homo sapiens]
Length = 499
Score = 172 bits (436), Expect = 5e-43
Identities = 96/349 (27%), Positives = 179/349 (51%), Gaps = 10/349 (2%)
Query: 71 NIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNFR-------KMPEKDLHEGFHYIIHEL 123
NIF++P+ ISTA M+ LG + T +++ +F+ K +H F + H L
Sbjct: 150 NIFIAPVGISTAMGMISLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHRL 209
Query: 124 TQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQ 183
++ L N L+I ++ F + +Y AE + +F + K N+ I +
Sbjct: 210 FRRNFGYTLRSVNDLYIQKQFPILLDFKTKVREYYFAEAQIADFSDPAFISKT-NNHIMK 268
Query: 184 KTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFR 243
T G I + +ENIDP T M++ N I+F+ W ++F +T +F L + VKV MM
Sbjct: 269 LTKGLIKDALENIDPATQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMMQT 328
Query: 244 SGIYQVGYDDKLSCTILEIPYQKNITAIFILPDE-GKLKHLEKGLQVDTFSRWKTLLSRR 302
G + D +L C IL++ Y I+ + ++P + +K LE L RW+ ++ R
Sbjct: 329 KGNFLAANDQELDCDILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNR 388
Query: 303 VVDVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLTKIAPHRSLKVGEAVHKAELKMDE 362
+V +P+ + ++L ++L +G+ +F+++G++ I+ R + + H+ + ++E
Sbjct: 389 TREVLLPKFKLEKNYNLVESLKLMGIRMLFDKNGNMAGISDQR-IAIDLFKHQGTITVNE 447
Query: 363 RGTEGAAGTGAQTLPMETPLVVKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
GT+ T +P+ T + +D+P+L LIY + +LF+G++ NP
Sbjct: 448 EGTQATTVTTVGFMPLSTQVRFTVDRPFLFLIYEHRTSCLLFMGRVANP 496
>gi|4826902 serine (or cysteine) proteinase inhibitor, clade B
(ovalbumin), member 10 [Homo sapiens]
Length = 397
Score = 171 bits (432), Expect = 1e-42
Identities = 111/394 (28%), Positives = 208/394 (52%), Gaps = 30/394 (7%)
Query: 48 LARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQGFNF--- 104
LA +L KKLA G+NIF S SIST+ +++ LGA+ +T ++ Q F
Sbjct: 4 LATSINQFALELSKKLAESAQGKNIFFSSWSISTSLTIVYLGAKGTTAAQMAQVLQFNRD 63
Query: 105 ------------RKMP-----EKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQ 147
RKM +++H F +I E+ + D L N ++ ++
Sbjct: 64 QGVKCDPESEKKRKMEFNLSNSEEIHSDFQTLISEILKPNDDYLLKTANAIYGEKTYAFH 123
Query: 148 RKFLEDAKNFYSAETILTNF-QNLEMAQKQINDFISQKTHGKINNLI--ENIDPGTVMLL 204
K+LED K ++ AE NF + + +K IN ++ ++T GKI NL+ +++D T M+L
Sbjct: 124 NKYLEDMKTYFGAEPQPVNFVEASDQIRKDINSWVERQTEGKIQNLLPDDSVDSTTRMIL 183
Query: 205 ANYIFFRARWKHEFDPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGYDDKLSCTILEIPY 264
N ++F+ W+H+F T E+ F + + +S V MMF + + +K L++ Y
Sbjct: 184 VNALYFKGIWEHQFLVQNTTEKPFRINETTSKPVQMMFMKKKLHIFHIEKPKAVGLQLYY 243
Query: 265 Q-KNITAIFILPDE-GKLKHLEKGLQVDTFSRWKT--LLSRRVVDVSVPRLHMTGTFDLK 320
+ ++++ + +LP++ L+ LEK + + + W + ++ V + +P+ + ++DLK
Sbjct: 244 KSRDLSLLILLPEDINGLEQLEKAITYEKLNEWTSADMMELYEVQLHLPKFKLEDSYDLK 303
Query: 321 KTLSYIGVSKIF-EEHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQ-TLPM 378
TLS +G+S F + D + ++ R+L + HKA ++++E+GTE AAG+G++ + +
Sbjct: 304 STLSSMGMSDAFSQSKADFSGMSSARNLFLSNVFHKAFVEINEQGTEAAAGSGSEIDIRI 363
Query: 379 ETPLV-VKIDKPYLLLIYSEKIPSVLFLGKIVNP 411
P + + P+L I K ++LF G++ +P
Sbjct: 364 RVPSIEFNANHPFLFFIRHNKTNTILFYGRLCSP 397
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.138 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,617,791
Number of Sequences: 37866
Number of extensions: 626533
Number of successful extensions: 1640
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1393
Number of HSP's gapped (non-prelim): 63
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.