Guide to the Human Genome
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Search of human proteins with 25453487

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25453487 cystathionase isoform 2 [Homo sapiens]
         (361 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25453487 cystathionase isoform 2 [Homo sapiens]                    729   0.0  
gi|21361334 cystathionase isoform 1 [Homo sapiens]                    708   0.0  
gi|109948292 hypothetical protein LOC57614 [Homo sapiens]              31   1.5  
gi|187960100 ubiquitin protein ligase E3C [Homo sapiens]               29   5.7  

>gi|25453487 cystathionase isoform 2 [Homo sapiens]
          Length = 361

 Score =  729 bits (1883), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 1   MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY 60
           MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY
Sbjct: 1   MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY 60

Query: 61  SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY 120
           SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY
Sbjct: 61  SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY 120

Query: 121 FRQVASEFGLKISFVDCSKIKLLEAAITPETKRPLALGADISMYSATKYMNGHSDVVMGL 180
           FRQVASEFGLKISFVDCSKIKLLEAAITPETKRPLALGADISMYSATKYMNGHSDVVMGL
Sbjct: 121 FRQVASEFGLKISFVDCSKIKLLEAAITPETKRPLALGADISMYSATKYMNGHSDVVMGL 180

Query: 181 VSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNP 240
           VSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNP
Sbjct: 181 VSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNP 240

Query: 241 WVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGF 300
           WVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGF
Sbjct: 241 WVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGF 300

Query: 301 ESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSH 360
           ESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSH
Sbjct: 301 ESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSH 360

Query: 361 S 361
           S
Sbjct: 361 S 361


>gi|21361334 cystathionase isoform 1 [Homo sapiens]
          Length = 405

 Score =  708 bits (1828), Expect = 0.0
 Identities = 361/405 (89%), Positives = 361/405 (89%), Gaps = 44/405 (10%)

Query: 1   MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY 60
           MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY
Sbjct: 1   MQEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEY 60

Query: 61  SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY 120
           SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY
Sbjct: 61  SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY 120

Query: 121 FRQVASEFGLKISFVDCSKIKLLEAAITPETK---------------------------- 152
           FRQVASEFGLKISFVDCSKIKLLEAAITPETK                            
Sbjct: 121 FRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG 180

Query: 153 ----------------RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQ 196
                           RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQ
Sbjct: 181 DIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQ 240

Query: 197 NSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQH 256
           NSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQH
Sbjct: 241 NSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQH 300

Query: 257 ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVL 316
           ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVL
Sbjct: 301 ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVL 360

Query: 317 KNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 361
           KNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS
Sbjct: 361 KNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 405


>gi|109948292 hypothetical protein LOC57614 [Homo sapiens]
          Length = 1216

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 9/108 (8%)

Query: 26  GQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSG---NPTRNCLEKAVAALDGAK 82
           G DP    S +   P++L ++ + G PG+ S    +  G    P R  ++   A L   +
Sbjct: 46  GLDPGSAGSLSPQDPVALGSSARPGLPGEASAAAVALGGTGETPARLSIDAIAAQLLRDQ 105

Query: 83  YCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGL 130
           Y       L A    T LL++G ++  + D +     + RQ  +  G+
Sbjct: 106 YL------LTALELHTELLESGRELPRLRDYFSNPGNFERQSGTPPGM 147


>gi|187960100 ubiquitin protein ligase E3C [Homo sapiens]
          Length = 1083

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 38/135 (28%), Positives = 55/135 (40%), Gaps = 20/135 (14%)

Query: 82   KYCLAFASGLAATVTITHL----------LKAGDQI-ICMDDVYGGTNRYFRQVASEFGL 130
            ++CLAF  GLA  V++  L          L +G Q+ I ++D+   TN      A    +
Sbjct: 934  QHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVI 993

Query: 131  KI------SFVDCSKIKLLEAAITPETKRPLALGADISMYSATKYMNGHSDVVMGLVSVN 184
            K+       F D  K KLL+        RP  LG    +Y A    NG SD+     +  
Sbjct: 994  KVFWRVVEGFTDEEKRKLLK--FVTSCSRPPLLGFK-ELYPAFCIHNGGSDLERLPTAST 1050

Query: 185  CESLHNRLRFLQNSL 199
            C +L     F   +L
Sbjct: 1051 CMNLLKLPEFYDETL 1065


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,842,731
Number of Sequences: 37866
Number of extensions: 577880
Number of successful extensions: 1407
Number of sequences better than 10.0: 4
Number of HSP's better than 10.0 without gapping: 2
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1404
Number of HSP's gapped (non-prelim): 5
length of query: 361
length of database: 18,247,518
effective HSP length: 104
effective length of query: 257
effective length of database: 14,309,454
effective search space: 3677529678
effective search space used: 3677529678
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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